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Jason Gestwicki

Research Profile

Chemicals & Drugs

Phenomena

Protein Binding

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Umesh Jinwal; Pengfei Li; Eckhard Mandelkow; Bryce A Nordhues; John C O'Leary; Andrea D Thompson; Vladimir N Uversky; Bo Zhang; Juan Zhang; Markus Zweckstetter; Jose F Abisambra; Elias Akoury; Justin Bacon; Jacek Biernat; Laura J Blair; Sergiy Borysov; Matthew Cockman; Jason E Gestwicki; Ying Jin; Chad A Dickey
Imbalance of Hsp70 family variants fosters tau accumulation.
Adrienne M Wang; Jason P Chua; Catherine A Collins; Jason E Gestwicki; Susan Klinedinst; Tomoko Komiyama; Xiaokai Li; Diane E Merry; Yoshinari Miyata; Yoshihiro Morishima; Yoichi Osawa; Hwei-Ming Peng; William B Pratt; Andrew P Lieberman
Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation.
Leah N Makley; Jason E Gestwicki
Expanding the number of 'druggable' targets: non-enzymes and protein-protein interactions.

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All Publications

2013: Umesh Jinwal; Pengfei Li; Eckhard Mandelkow; Bryce A Nordhues; John C O'Leary; Andrea D Thompson; Vladimir N Uversky; Bo Zhang; Juan Zhang; Markus Zweckstetter; Jose F Abisambra; Elias Akoury; Justin Bacon; Jacek Biernat; Laura J Blair; Sergiy Borysov; Matthew Cockman; Jason E Gestwicki; Ying Jin; Chad A Dickey
Imbalance of Hsp70 family variants fosters tau accumulation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013;27(4):1450-9.
2013: Adrienne M Wang; Jason P Chua; Catherine A Collins; Jason E Gestwicki; Susan Klinedinst; Tomoko Komiyama; Xiaokai Li; Diane E Merry; Yoshinari Miyata; Yoshihiro Morishima; Yoichi Osawa; Hwei-Ming Peng; William B Pratt; Andrew P Lieberman
Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation.
Nature chemical biology 2013;9(2):112-8.
2013: Leah N Makley; Jason E Gestwicki
Expanding the number of 'druggable' targets: non-enzymes and protein-protein interactions.
Chemical biology & drug design 2013;81(1):22-32.
2013: Victoria A Assimon; Anne T Gillies; Jennifer N Rauch; Jason E Gestwicki
Hsp70 protein complexes as drug targets.
Current pharmaceutical design 2013;19(3):404-17.
2013: Erik R P Zuiderweg; Eric B Bertelsen; Jason E Gestwicki; Matthias P Mayer; Aikaterini Rousaki; Atta Ahmad
Allostery in the Hsp70 chaperone proteins.
Topics in current chemistry 2013;328():99-153.
2012: Yoshinari Miyata; Jennifer N Rauch; Sharan Srinivasan; Andrea D Thompson; Chad A Dickey; Umesh Jinwal; Jason E Gestwicki
Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70.
Chemistry & biology 2012;19(11):1391-9.
2012: Anne T Gillies; Rebecca Taylor; Jason E Gestwicki
Synthetic lethal interactions in yeast reveal functional roles of J protein co-chaperones.
Molecular bioSystems 2012;8(11):2901-8.
2012: Sandlin P Seguin; Peter Wipf; Christine M Wright; Jason E Gestwicki; Tushar Gupta; Alex W Ireland; Yoshinari Miyata; James M Pipas; Jeffrey L Brodsky
A screen for modulators of large T antigen's ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication.
Antiviral research 2012;96(1):70-81.
2012: Sidhartha M Chafekar; AnaLisa Echeverria; Christopher G Evans; Jason E Gestwicki; Leah N Makley; Andrea D Thompson; Gladis M Walter; Susanne Wisén; Martin L Duennwald
Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation.
ACS chemical biology 2012;7(9):1556-64.
2012: Neal D Hammer; Bryan A McGuffie; Anders Olofsson; Ashley A Reinke; Yizhou Zhou; Fredrik Almqvist; Matthew P Badtke; Kristoffer Brännström; Jason E Gestwicki; Matthew R Chapman
The C-terminal repeating units of CsgB direct bacterial functional amyloid nucleation.
Journal of molecular biology 2012;422(3):376-89.
2012: Sharan R Srinivasan; Andrea D Thompson; Lyra Chang; Anne T Gillies; Jason E Gestwicki
Molecular chaperones DnaK and DnaJ share predicted binding sites on most proteins in the E. coli proteome.
Molecular bioSystems 2012;8(9):2323-33.
2012: Andrea D Thompson; Amanda Dugan; Jason E Gestwicki; Anna K Mapp
Fine-tuning multiprotein complexes using small molecules.
ACS chemical biology 2012;7(8):1311-20.
2012: Umesh Jinwal; John C O'Leary; Tina Patel; Juan Zhang; Jose F Abisambra; Kaitlyn Braswell; Sheetal Dharia; Jason E Gestwicki; Twisha Jani; Chad A Dickey
Cdc37/Hsp90 protein complex disruption triggers an autophagic clearance cascade for TDP-43 protein.
The Journal of biological chemistry 2012;287(29):24814-20.
2012: Andrea D Thompson; Leah N Makley; Kathryn McMenimen; Jason E Gestwicki
The three cornerstones of chemical biology: innovative probes, new discoveries, and enabling tools.
ACS chemical biology 2012;7(5):791-6.
2012: Andrea D Thompson; georgios skiniotis; Steffen M Bernard; Jason E Gestwicki
Visualization and functional analysis of the oligomeric states of Escherichia coli heat shock protein 70 (Hsp70/DnaK).
Cell stress & chaperones 2012;17(3):313-27.
2012: Erin E Congdon; Chad A Dickey; Yvette H Figueroa; Jason E Gestwicki; Mathieu Herman; Paul S Marinec; Natura Myeku; Jessica W Wu; W Haung Yu; Karen E Duff
Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo.
Autophagy 2012;8(4):609-22.
2012: Matthew C Smith; Jason E Gestwicki
Features of protein-protein interactions that translate into potent inhibitors: topology, surface area and affinity.
Expert reviews in molecular medicine 2012;14():e16.
2012: John Koren; Xiaokai Li; Yoshinari Miyata; Lana Nguyen; John C O'Leary; Xiokai Li; Jason E Gestwicki; Jianping Guo; Umesh Jinwal; Janine Kiray; Laura J Blair; Jin Q Cheng; Chad A Dickey
Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance.
PloS one 2012;7(4):e35566.
2012: Jason E Gestwicki; Dan Garza
Protein quality control in neurodegenerative disease.
Progress in molecular biology and translational science 2012;107():327-53.
2011: Gladis M Walter; Susanne Wisén; Anuj Kumar; Matthew C Smith; venkatesha basrur; Martin L Duennwald; Kojo Seys John Elenitoba-Johnson; Jason E Gestwicki
Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes.
The Journal of biological chemistry 2011;286(47):40486-93.
2011: Yoshinari Miyata; Chad A Dickey; Janine Kiray; John Koren; Jason E Gestwicki
Molecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies.
Future medicinal chemistry 2011;3(12):1523-37.
2011: Yoshihiro Morishima; Jason E Gestwicki; Miranda Lau; Yoshinari Miyata; Hwei-Ming Peng; William B Pratt; Yoichi Osawa
Heme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleft.
Biochemistry 2011;50(33):7146-56.
2011: kenneth Scaglione; Sokol Todi; Ping Xu; Eszter Zavodszky; Ana Djarmati; Svetlana Fischer; Jason E Gestwicki; John Konen; Srikanth Patury; Junmin Peng; Edgardo Rodriguez; Henry L Paulson
Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP.
Molecular cell 2011;43(4):599-612.
2011: Aikaterini Rousaki; Chad A Dickey; Jason E Gestwicki; Umesh Jinwal; Yoshinari Miyata; Erik R P Zuiderweg
Allosteric drugs: the interaction of antitumor compound MKT-077 with human Hsp70 chaperones.
Journal of molecular biology 2011;411(3):614-32.
2011: Christopher G Evans; Matthew C Smith; James P Carolan; Jason E Gestwicki
Improved synthesis of 15-deoxyspergualin analogs using the Ugi multi-component reaction.
Bioorganic & medicinal chemistry letters 2011;21(9):2587-90.
2011: Anthony Bainor; Lyra Chang; Thomas J McQuade; Brian Webb; Jason E Gestwicki
Bicinchoninic acid (BCA) assay in low volume.
Analytical biochemistry 2011;410(2):310-2.
2011: Lyra Chang; Yoshinari Miyata; Peter M U Ung; Eric B Bertelsen; Thomas J McQuade; Heather A Carlson; Erik R P Zuiderweg; Jason E Gestwicki
Chemical screens against a reconstituted multiprotein complex: myricetin blocks DnaJ regulation of DnaK through an allosteric mechanism.
Chemistry & biology 2011;18(2):210-21.
2011: Christopher G Evans; Umesh K Jinwal; Leah N Makley; Chad A Dickey; Jason E Gestwicki
Identification of dihydropyridines that reduce cellular tau levels.
Chemical communications (Cambridge, England) 2011;47(1):529-31.
2010: Ashley A Reinke; Peter M U Ung; Jerome J Quintero; Heather A Carlson; Jason E Gestwicki
Chemical probes that selectively recognize the earliest Aβ oligomers in complex mixtures.
Journal of the American Chemical Society 2010;132(50):17655-7.
2010: Yoshinari Miyata; Lyra Chang; Anthony Bainor; Thomas J McQuade; Christopher P Walczak; Yaru Zhang; Martha J Larsen; Paul Kirchhoff; Jason E Gestwicki
High-throughput screen for Escherichia coli heat shock protein 70 (Hsp70/DnaK): ATPase assay in low volume by exploiting energy transfer.
Journal of biomolecular screening 2010;15(10):1211-9.
2010: Tao Xu; Cole A Johnson; Jason E Gestwicki; Anuj Kumar
Conditionally controlling nuclear trafficking in yeast by chemical-induced protein dimerization.
Nature protocols 2010;5(11):1831-43.
2010: Ashley A Reinke; Gelareh A Abulwerdi; Jason E Gestwicki
Quantifying prefibrillar amyloids in vitro by using a "thioflavin-like" spectroscopic method.
Chembiochem : a European journal of chemical biology 2010;11(13):1889-95.
2010: Lyra Chang; Andrea D Thompson; Peter Ung; Heather A Carlson; Jason E Gestwicki
Mutagenesis reveals the complex relationships between ATPase rate and the chaperone activities of Escherichia coli heat shock protein 70 (Hsp70/DnaK).
The Journal of biological chemistry 2010;285(28):21282-91.
2010: Christopher G Evans; Lyra Chang; Jason E Gestwicki
Heat shock protein 70 (hsp70) as an emerging drug target.
Journal of medicinal chemistry 2010;53(12):4585-602.
2010: Susanne Wisén; Eric B Bertelsen; Andrea D Thompson; Srikanth Patury; Peter Ung; Lyra Chang; Christopher G Evans; Gladis M Walter; Peter Wipf; Heather A Carlson; Jeffrey L Brodsky; Erik R P Zuiderweg; Jason E Gestwicki
Binding of a small molecule at a protein-protein interface regulates the chaperone activity of hsp70-hsp40.
ACS chemical biology 2010;5(6):611-22.
2010: Umesh Jinwal; John C O'Leary; Sergiy I Borysov; Jeffrey R Jones; Qingyou Li; John Koren; Jose F Abisambra; Grant D Vestal; Lisa Y Lawson; Amelia G Johnson; Laura J Blair; Ying Jin; Yoshinari Miyata; Jason E Gestwicki; Chad A Dickey
Hsc70 rapidly engages tau after microtubule destabilization.
The Journal of biological chemistry 2010;285(22):16798-805.
2010: Adrienne M Wang; Yoshihiro Morishima; Kelly M Clapp; Hwei-Ming Peng; William B Pratt; Jason E Gestwicki; Yoichi Osawa; Andrew P Lieberman
Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation.
The Journal of biological chemistry 2010;285(21):15714-23.
2010: Jason E Gestwicki
Special series: Molecular chaperones in protein folding and disease.
Biopolymers 2010;93(3):209-10.
2010: John Koren; Umesh Jinwal; Ying Jin; John O'Leary; Jeff R Jones; Amelia G Johnson; Laura J Blair; Jose F Abisambra; Lyra Chang; Yoshinari Miyata; Anna M Cheng; Jianping Guo; Jin Q Cheng; Jason E Gestwicki; Chad A Dickey
Facilitating Akt clearance via manipulation of Hsp70 activity and levels.
The Journal of biological chemistry 2010;285(4):2498-505.
2010: John C O'Leary; Qingyou Li; Paul Marinec; Laura J Blair; Erin E Congdon; Amelia G Johnson; Umesh Jinwal; John Koren; Jeffrey R Jones; Clara Kraft; Melinda Peters; Jose F Abisambra; Karen E Duff; Edwin J Weeber; Jason E Gestwicki; Chad A Dickey
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden.
Molecular neurodegeneration 2010;5():45.
2009: Umesh Jinwal; Yoshinari Miyata; John Koren; Jeffrey R Jones; Justin H Trotter; Lyra Chang; John O'Leary; Dave Morgan; Daniel C Lee; Cody L Shults; Aikaterini Rousaki; Edwin J Weeber; Erik R P Zuiderweg; Jason E Gestwicki; Chad A Dickey
Chemical manipulation of hsp70 ATPase activity regulates tau stability.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(39):12079-88.
2009: Ashley A Reinke; Han Yiau Seh; Jason E Gestwicki
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
Bioorganic & medicinal chemistry letters 2009;19(17):4952-7.
2009: Paul S Marinec; Christopher G Evans; Garrett S Gibbons; Malloree A Tarnowski; Daniel L Overbeek; Jason E Gestwicki
Synthesis of orthogonally reactive FK506 derivatives via olefin cross metathesis.
Bioorganic & medicinal chemistry 2009;17(16):5763-8.
2009: Christopher G Evans; Jason E Gestwicki
Enantioselective organocatalytic Hantzsch synthesis of polyhydroquinolines.
Organic letters 2009;11(14):2957-9.
2009: Eric B Bertelsen; Lyra Chang; Jason E Gestwicki; Erik R P Zuiderweg
Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(21):8471-6.
2009: Katrina W Lexa; Kelly L Damm; Jerome J Quintero; Jason E Gestwicki; Heather A Carlson
Clarifying allosteric control of flap conformations in the 1TW7 crystal structure of HIV-1 protease.
Proteins 2009;74(4):872-80.
2009: Paul S Marinec; Lei Chen; Kenneth J Barr; Mitchell W Mutz; Gerald R Crabtree; Jason E Gestwicki
FK506-binding protein (FKBP) partitions a modified HIV protease inhibitor into blood cells and prolongs its lifetime in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(5):1336-41.
2009: Srikanth Patury; Yoshinari Miyata; Jason E Gestwicki
Pharmacological targeting of the Hsp70 chaperone.
Current topics in medicinal chemistry 2009;9(15):1337-51.
2009: Srikanth Patury; Prasanthi Geda; Craig J Dobry; Anuj Kumar; Jason E Gestwicki
Conditional nuclear import and export of yeast proteins using a chemical inducer of dimerization.
Cell biochemistry and biophysics 2009;53(3):127-34.
2008: Prasanthi Geda; Srikanth Patury; Jun Ma; Nike Bharucha; Craig J Dobry; Sarah K Lawson; Jason E Gestwicki; Anuj Kumar
A small molecule-directed approach to control protein localization and function.
Yeast (Chichester, England) 2008;25(8):577-94.
2008: Kelly L Damm; Peter M U Ung; Jerome J Quintero; Jason E Gestwicki; Heather A Carlson
A poke in the eye: inhibiting HIV-1 protease through its flap-recognition pocket.
Biopolymers 2008;89(8):643-52.
2008: Jason E Gestwicki
The interface of chemistry and biology is actually a continuum.
ACS chemical biology 2008;3(6):328-34.
2008: Paul S Marinec; Jody K Lancia; Jason E Gestwicki
Bifunctional molecules evade cytochrome P(450) metabolism by forming protective complexes with FK506-binding protein.
Molecular bioSystems 2008;4(6):571-8.
2008: Susanne Wisén; Jason E Gestwicki
Identification of small molecules that modify the protein folding activity of heat shock protein 70.
Analytical biochemistry 2008;374(2):371-7.
2008: Lyra Chang; Eric B Bertelsen; Susanne Wisén; Erik M Larsen; Erik R P Zuiderweg; Jason E Gestwicki
High-throughput screen for small molecules that modulate the ATPase activity of the molecular chaperone DnaK.
Analytical biochemistry 2008;372(2):167-76.
2008: Susanne Wisén; John Androsavich; Christopher G Evans; Lyra Chang; Jason E Gestwicki
Chemical modulators of heat shock protein 70 (Hsp70) by sequential, microwave-accelerated reactions on solid phase.
Bioorganic & medicinal chemistry letters 2008;18(1):60-5.
2007: M Kyle Hadden; Lakshmi Galam; Jason E Gestwicki; Robert L Matts; Brian S J Blagg
Derrubone, an inhibitor of the Hsp90 protein folding machinery.
Journal of natural products 2007;70(12):2014-8.
2007: Jason E Gestwicki; Paul S Marinec
Chemical control over protein-protein interactions: beyond inhibitors.
Combinatorial chemistry & high throughput screening 2007;10(8):667-75.
2007: Ashley A Reinke; Jason E Gestwicki
Structure-activity relationships of amyloid beta-aggregation inhibitors based on curcumin: influence of linker length and flexibility.
Chemical biology & drug design 2007;70(3):206-15.
2007: Kryn Stankunas; J Henri Bayle; James J Havranek; Thomas J Wandless; David Baker; Gerald R Crabtree; Jason E Gestwicki
Rescue of degradation-prone mutants of the FK506-rapamycin binding (FRB) protein with chemical ligands.
Chembiochem : a European journal of chemical biology 2007;8(10):1162-9.
2007: David C Rubinsztein; Jason E Gestwicki; Leon O Murphy; Daniel J Klionsky
Potential therapeutic applications of autophagy.
Nature reviews. Drug discovery 2007;6(4):304-12.
2006: Christopher G Evans; Susanne Wisén; Jason E Gestwicki
Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro.
The Journal of biological chemistry 2006;281(44):33182-91.
2006: Jason E Gestwicki
Reclamation of proteins from the cellular scrap heap.
ACS chemical biology 2006;1(4):201-3.
2006: Laura L Kiessling; Jason E Gestwicki; Laura E Strong
Synthetic multivalent ligands as probes of signal transduction.
Angewandte Chemie (International ed. in English) 2006;45(15):2348-68.
2006: J Henri Bayle; Joshua S Grimley; Kryn Stankunas; Jason E Gestwicki; Thomas J Wandless; Gerald R Crabtree
Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity.
Chemistry & biology 2006;13(1):99-107.
2005: M Bose; Jason E Gestwicki; V Devasthali; Gerald R Crabtree; ISabella Graef
'Nature-inspired' drug-protein complexes as inhibitors of Abeta aggregation.
Biochemical Society transactions 2005;33(Pt 4):543-7.
2005: Jason E Gestwicki
Target identification for a promising anti-lupus drug.
Chemistry & biology 2005;12(4):414-5.
2004: Jason E Gestwicki; Gerald R Crabtree; ISabella Graef
Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation.
Science (New York, N.Y.) 2004;306(5697):865-9.
2004: Ching-Pin Chang; Joel R Neilson; J Henri Bayle; Jason E Gestwicki; Ann Kuo; Kryn Stankunas; ISabella Graef; Gerald R Crabtree
A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesis.
Cell 2004;118(5):649-63.
2003: Kryn Stankunas; J Henri Bayle; Jason E Gestwicki; Yun-Ming Lin; Thomas J Wandless; Gerald R Crabtree
Conditional protein alleles using knockin mice and a chemical inducer of dimerization.
Molecular cell 2003;12(6):1615-24.
2003: Jason E Gestwicki; Christopher W Cairo; M Jack Borrok; Laura L Kiessling
Visualization and characterization of receptor clusters by transmission electron microscopy.
Methods in enzymology 2003;362():301-12.
2002: Jason E Gestwicki; Christopher W Cairo; Laura E Strong; Karolyn A Oetjen; Laura L Kiessling
Influencing receptor-ligand binding mechanisms with multivalent ligand architecture.
Journal of the American Chemical Society 2002;124(50):14922-33.
2002: Allison C Lamanna; Jason E Gestwicki; Laura E Strong; Sara L Borchardt; Robert M. Owen; Laura L Kiessling
Conserved amplification of chemotactic responses through chemoreceptor interactions.
Journal of bacteriology 2002;184(18):4981-7.
2002: Robert M. Owen; Jason E Gestwicki; Travis Young; Laura L Kiessling
Synthesis and applications of end-labeled neoglycopolymers.
Organic letters 2002;4(14):2293-6.
2002: Jason E Gestwicki; Christopher W Cairo; David A Mann; Robert M. Owen; Laura L Kiessling
Selective immobilization of multivalent ligands for surface plasmon resonance and fluorescence microscopy.
Analytical biochemistry 2002;305(2):149-55.
2002: Christopher W Cairo; Jason E Gestwicki; Motomu Kanai; Laura L Kiessling
Control of multivalent interactions by binding epitope density.
Journal of the American Chemical Society 2002;124(8):1615-9.
2002: Jason E Gestwicki; Laura E Strong; Christopher W Cairo; Frederick J Boehm; Laura L Kiessling
Cell aggregation by scaffolded receptor clusters.
Chemistry & biology 2002;9(2):163-9.
2002: Jason E Gestwicki; Laura L Kiessling
Inter-receptor communication through arrays of bacterial chemoreceptors.
Nature 2002;415(6867):81-4.
2001: Jason E Gestwicki; H V Hsieh; J Bruce Pitner
Using receptor conformational change to detect low molecular weight analytes by surface plasmon resonance.
Analytical chemistry 2001;73(23):5732-7.
2001: Jason E Gestwicki; Laura E Strong; S L Borchardt; Christopher W Cairo; A M Schnoes; Laura L Kiessling
Designed potent multivalent chemoattractants for Escherichia coli.
Bioorganic & medicinal chemistry 2001;9(9):2387-93.
2000: Laura L Kiessling; Jason E Gestwicki; Laura E Strong
Synthetic multivalent ligands in the exploration of cell-surface interactions.
Current opinion in chemical biology 2000;4(6):696-703.
2000: Jason E Gestwicki; Allison C Lamanna; R M Harshey; L L McCarter; Laura L Kiessling; J Adler
Evolutionary conservation of methyl-accepting chemotaxis protein location in Bacteria and Archaea.
Journal of bacteriology 2000;182(22):6499-502.
2000: Kathleen A Hoag; K Clise-Dwyer; Y H Lim; Faye E Nashold; Jason E Gestwicki; Michael P Cancro; Colleen E Hayes
A quantitative-trait locus controlling peripheral B-cell deficiency maps to mouse Chromosome 15.
Immunogenetics 2000;51(11):924-9.
2000: Jason E Gestwicki; Laura E Strong; Laura L Kiessling
Tuning chemotactic responses with synthetic multivalent ligands.
Chemistry & biology 2000;7(8):583-91.
2000: N Maki; Jason E Gestwicki; E M Lake; Laura L Kiessling; J Adler
Motility and chemotaxis of filamentous cells of Escherichia coli.
Journal of bacteriology 2000;182(15):4337-42.
2000: Eva J Gordon; Jason E Gestwicki; Laura E Strong; Laura L Kiessling
Synthesis of end-labeled multivalent ligands for exploring cell-surface-receptor-ligand interactions.
Chemistry & biology 2000;7(1):9-16.