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JOAQUIM ROCA

Research Profile

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Publications

TOP 3
Erika Ercolini; Francesco Valle; Jozef Adamcik; Guillaume Witz; Ralf Metzler; Paolo De los Rios; JOAQUIM ROCA; Giovanni Dietler
Fractal dimension and localization of DNA knots.
Sonia Trigueros; JOAQUIM ROCA
Production of highly knotted DNA by means of cosmid circularization inside phage capsids.
Javier Salceda; Xavier Fernández; JOAQUIM ROCA
Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA.

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All Publications

2007: Erika Ercolini; Francesco Valle; Jozef Adamcik; Guillaume Witz; Ralf Metzler; Paolo De los Rios; JOAQUIM ROCA; Giovanni Dietler
Fractal dimension and localization of DNA knots.
Physical review letters 2007;98(5):058102.
2007: Sonia Trigueros; JOAQUIM ROCA
Production of highly knotted DNA by means of cosmid circularization inside phage capsids.
BMC biotechnology 2007;7():94.
2006: Javier Salceda; Xavier Fernández; JOAQUIM ROCA
Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA.
The EMBO journal 2006;25(11):2575-83.
2006: Chaysavanh Manichanh; L Rigottier-Gois; E Bonnaud; Karine Gloux; E Pelletier; L Frangeul; Renaud Nalin; Cyrille Jarrin; P Chardon; Philippe Marteau; JOAQUIM ROCA; J Dore
Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach.
Gut 2006;55(2):205-11.
2005: Juan Luis Arsuaga Ferreras; Mariel Vazquez; Paul McGuirk; Sonia Trigueros; De Witt Sumners; JOAQUIM ROCA
DNA knots reveal a chiral organization of DNA in phage capsids.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9165-9.
2004: JOAQUIM ROCA
The path of the DNA along the dimer interface of topoisomerase II.
The Journal of biological chemistry 2004;279(24):25783-8.
2004: Sonia Trigueros; Javier Salceda; Ignacio Bermúdez; Xavier Fernández; JOAQUIM ROCA
Asymmetric removal of supercoils suggests how topoisomerase II simplifies DNA topology.
Journal of molecular biology 2004;335(3):723-31.
2002: Sonia Trigueros; JOAQUIM ROCA
Failure to relax negative supercoiling of DNA is a primary cause of mitotic hyper-recombination in topoisomerase-deficient yeast cells.
The Journal of biological chemistry 2002;277(40):37207-11.
2002: Juan Luis Arsuaga Ferreras; Mariel Vázquez; Sonia Trigueros; De Witt Sumners; JOAQUIM ROCA
Knotting probability of DNA molecules confined in restricted volumes: DNA knotting in phage capsids.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5373-7.
2002: Sonia Trigueros; JOAQUIM ROCA
A GyrB-GyrA fusion protein expressed in yeast cells is able to remove DNA supercoils but cannot substitute eukaryotic topoisomerase II.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(3):249-57.
2001: Sonia Trigueros; Juan Luis Arsuaga Ferreras; M E Vazquez; De Witt Sumners; JOAQUIM ROCA
Novel display of knotted DNA molecules by two-dimensional gel electrophoresis.
Nucleic acids research 2001;29(13):E67-7.
2001: JOAQUIM ROCA
Varying levels of positive and negative supercoiling differently affect the efficiency with which topoisomerase II catenates and decatenates DNA.
Journal of molecular biology 2001;305(3):441-50.
2001: Sonia Trigueros; JOAQUIM ROCA
Circular minichromosomes become highly recombinogenic in topoisomerase-deficient yeast cells.
The Journal of biological chemistry 2001;276(3):2243-8.
2001: JOAQUIM ROCA
Filter binding assays for topoisomerase-DNA complexes.
Methods in molecular biology (Clifton, N.J.) 2001;95():75-80.
1999: Ryo Hanai; JOAQUIM ROCA
Two-dimensional agarose-gel electrophoresis of DNA topoisomers.
Methods in molecular biology (Clifton, N.J.) 1999;94():19-27.
1996: JOAQUIM ROCA; J M Berger; S C Harrison; James C Wang
DNA transport by a type II topoisomerase: direct evidence for a two-gate mechanism.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4057-62.
1996: JOAQUIM ROCA; James C Wang
The probabilities of supercoil removal and decatenation by yeast DNA topoisomerase II.
Genes to cells : devoted to molecular & cellular mechanisms 1996;1(1):17-27.
1995: JOAQUIM ROCA
The mechanisms of DNA topoisomerases.
Trends in biochemical sciences 1995;20(4):156-60.
1994: JOAQUIM ROCA; James C Wang
DNA transport by a type II DNA topoisomerase: evidence in favor of a two-gate mechanism.
Cell 1994;77(4):609-16.
1994: JOAQUIM ROCA; R Ishida; J M Berger; T Andoh; James C Wang
Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1781-5.
1993: JOAQUIM ROCA; J M Berger; James C Wang
On the simultaneous binding of eukaryotic DNA topoisomerase II to a pair of double-stranded DNA helices.
The Journal of biological chemistry 1993;268(19):14250-5.
1993: J Boix; JOAQUIM ROCA
Separation of rooster spermatogenic nuclei by means of centrifugal elutriation.
Cytometry 1993;14(4):465-7.
1992: JOAQUIM ROCA; James C Wang
The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases.
Cell 1992;71(5):833-40.
1992: JOAQUIM ROCA; M R Gartenberg; Y Oshima; J C Wang
A hit-and-run system for targeted genetic manipulations in yeast.
Nucleic acids research 1992;20(17):4671-2.
1989: JOAQUIM ROCA; Cristobal Mezquita
DNA topoisomerase II activity in nonreplicating, transcriptionally inactive, chicken late spermatids.
The EMBO journal 1989;8(6):1855-60.