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Patrizia Lavia

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Mouse

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Wen Fong Ooi; Valentina Adami; Natalia Arseni; Valentina Canella; Maria Giubettini; Giulia Guarguaglini; Patrizia Lavia; Angela Re; Paola Scaruffi; Viktoryia Sidarovich; Sara Stigliani; Gian Paolo Tonini; Alessandro Quattrone
Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high-risk neuroblastoma.
Emanuele Roscioli; Maria Eugenia Schininà; Serena Orlando; Alessio Bolognesi; Laura Di Francesco; Maria Giubettini; Amnon Harel; Patrizia Lavia
Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores.
Gianluca Sbardella; Ilaria Sciamanna; Annalucia Serafino; Sara Bartolini; Sabrina Castellano; Roberto Cirilli; Patrizia Lavia; Antonello Mai; Ciro Milite; Serena Orlando; dante rotili; Marisabella Santoriello; Corrado Spadafora
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors.

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All Publications

2012: Wen Fong Ooi; Valentina Adami; Natalia Arseni; Valentina Canella; Maria Giubettini; Giulia Guarguaglini; Patrizia Lavia; Angela Re; Paola Scaruffi; Viktoryia Sidarovich; Sara Stigliani; Gian Paolo Tonini; Alessandro Quattrone
Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high-risk neuroblastoma.
Genes, chromosomes & cancer 2012;51(6):545-56.
2012: Emanuele Roscioli; Maria Eugenia Schininà; Serena Orlando; Alessio Bolognesi; Laura Di Francesco; Maria Giubettini; Amnon Harel; Patrizia Lavia
Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores.
The Journal of cell biology 2012;196(4):435-50.
2011: Gianluca Sbardella; Ilaria Sciamanna; Annalucia Serafino; Sara Bartolini; Sabrina Castellano; Roberto Cirilli; Patrizia Lavia; Antonello Mai; Ciro Milite; Serena Orlando; dante rotili; Marisabella Santoriello; Corrado Spadafora
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors.
Journal of medicinal chemistry 2011;54(16):5927-36.
2011: Italia A Asteriti; Maria Giubettini; Patrizia Lavia; Giulia Guarguaglini
Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces.
Molecular cancer 2011;10():131.
2011: Maria Giubettini; Italia A Asteriti; Jacopo Scrofani; Maria De Luca; Catherine Lindon; Patrizia Lavia; Giulia Guarguaglini
Control of Aurora-A stability through interaction with TPX2.
Journal of cell science 2011;124(Pt 1):113-22.
2010: Emanuele Roscioli; Alessio Bolognesi; Giulia Guarguaglini; Patrizia Lavia
Ran control of mitosis in human cells: gradients and local signals.
Biochemical Society transactions 2010;38(6):1709-14.
2010: Italia Anna Asteriti; Wilhelmina Maria Rensen; Catherine Lindon; Patrizia Lavia; Giulia Guarguaglini
The Aurora-A/TPX2 complex: a novel oncogenic holoenzyme?
Biochimica et biophysica acta 2010;1806(2):230-9.
2010: Marilena Ciciarello; Emanuele Roscioli; Barbara Di Fiore; Laura Di Francesco; Fabrizia Sobrero; Delphine Bernard; Rosamaria Mangiacasale; Amnon Harel; Maria Eugenia Schininà; Patrizia Lavia
Nuclear reformation after mitosis requires downregulation of the Ran GTPase effector RanBP1 in mammalian cells.
Chromosoma 2010;119(6):651-68.
2009: W M Rensen; E Roscioli; A Tedeschi; Rosamaria Mangiacasale; Marilena Ciciarello; S A Di Gioia; Patrizia Lavia
RanBP1 downregulation sensitizes cancer cells to taxol in a caspase-3-dependent manner.
Oncogene 2009;28(15):1748-58.
2008: Maria De Luca; L Brunetto; I A Asteriti; M Giubettini; Patrizia Lavia; Giulia Guarguaglini
Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity.
Oncogene 2008;27(51):6539-49.
2008: Liliana Torosantucci; Maria De Luca; Giulia Guarguaglini; Patrizia Lavia; Francesca Degrassi
Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells.
Molecular biology of the cell 2008;19(5):1873-82.
2008: Wilhelmina M Rensen; Rosamaria Mangiacasale; Marilena Ciciarello; Patrizia Lavia
The GTPase Ran: regulation of cell life and potential roles in cell transformation.
Frontiers in bioscience : a journal and virtual library 2008;13():4097-121.
2007: Antonio Tedeschi; Marilena Ciciarello; Rosamaria Mangiacasale; Emanuele Roscioli; Wilhelmina M Rensen; Patrizia Lavia
RANBP1 localizes a subset of mitotic regulatory factors on spindle microtubules and regulates chromosome segregation in human cells.
Journal of cell science 2007;120(Pt 21):3748-61.
2007: Marilena Ciciarello; Rosamaria Mangiacasale; Patrizia Lavia
Spatial control of mitosis by the GTPase Ran.
Cellular and molecular life sciences : CMLS 2007;64(15):1891-914.
2006: Maria De Luca; Patrizia Lavia; Giulia Guarguaglini
A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association.
Cell cycle (Georgetown, Tex.) 2006;5(3):296-303.
2006: Paola Sinibaldi-Vallebona; Patrizia Lavia; Enrico Garaci; Corrado Spadafora
A role for endogenous reverse transcriptase in tumorigenesis and as a target in differentiating cancer therapy.
Genes, chromosomes & cancer 2006;45(1):1-10.
2005: Paola Merlo; Marcella Fulco; Antonio Costanzo; Rosamaria Mangiacasale; Sabrina Strano; Giovanni Blandino; Yoichi Taya; Patrizia Lavia; Massimo Levrero
A role of p73 in mitotic exit.
The Journal of biological chemistry 2005;280(34):30354-60.
2005: Marilena Ciciarello; Patrizia Lavia
New CRIME plots. Ran and transport factors regulate mitosis.
EMBO reports 2005;6(8):714-6.
2004: Marilena Ciciarello; Rosamaria Mangiacasale; Catherine Thibier; Giulia Guarguaglini; Enzo Marchetti; Barbara Di Fiore; Patrizia Lavia
Importin beta is transported to spindle poles during mitosis and regulates Ran-dependent spindle assembly factors in mammalian cells.
Journal of cell science 2004;117(Pt 26):6511-22.
2004: A Tritarelli; E Oricchio; Marilena Ciciarello; Rosamaria Mangiacasale; Antonella Palena; Patrizia Lavia; Silvia Soddu; Enrico Cundari
p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation.
Molecular biology of the cell 2004;15(8):3751-7.
2004: Barbara Di Fiore; Marilena Ciciarello; Patrizia Lavia
Mitotic functions of the Ran GTPase network: the importance of being in the right place at the right time.
Cell cycle (Georgetown, Tex.) 2004;3(3):305-13.
2003: Marcella Fulco; Antonio Costanzo; Paola Merlo; Rosamaria Mangiacasale; Sabrina Strano; Giovanni Blandino; Clara Balsano; Patrizia Lavia; Massimo Levrero
p73 is regulated by phosphorylation at the G2/M transition.
The Journal of biological chemistry 2003;278(49):49196-202.
2003: Guy Keryer; Barbara Di Fiore; Claude Celati; Karl-Ferdinand Lechtreck; Mette M Mogensen; Annie Delouvee; Patrizia Lavia; Michel Bornens; Anne-Marie Tassin
Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity.
Molecular biology of the cell 2003;14(10):4260-71.
2003: Patrizia Lavia; Anna Maria Mileo; Antonio Giordano; Marco Giorgio Paggi
Emerging roles of DNA tumor viruses in cell proliferation: new insights into genomic instability.
Oncogene 2003;22(42):6508-16.
2003: Barbara Di Fiore; Marilena Ciciarello; Rosamaria Mangiacasale; Antonella Palena; Anne-Marie Tassin; Enrico Cundari; Patrizia Lavia
Mammalian RanBP1 regulates centrosome cohesion during mitosis.
Journal of cell science 2003;116(Pt 16):3399-411.
2003: Rosamaria Mangiacasale; Carmine Pittoggi; Ilaria Sciamanna; Angela Careddu; Elisabetta Mattei; Rodolfo Lorenzini; Lorena Travaglini; Matteo Landriscina; Carlo Barone; Clara Nervi; Patrizia Lavia; Corrado Spadafora
Exposure of normal and transformed cells to nevirapine, a reverse transcriptase inhibitor, reduces cell growth and promotes differentiation.
Oncogene 2003;22(18):2750-61.
2003: Antonio De Luca; Rosamaria Mangiacasale; Anna Severino; Lorenzo Malquori; Alfonso Baldi; Antonella Palena; Anna Maria Mileo; Patrizia Lavia; Marco Giorgio Paggi
E1A deregulates the centrosome cycle in a Ran GTPase-dependent manner.
Cancer research 2003;63(6):1430-7.
2001: Marilena Ciciarello; Rosamaria Mangiacasale; M Casenghi; M Zaira Limongi; M D'Angelo; Silvia Soddu; Patrizia Lavia; Enrico Cundari
p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle.
The Journal of biological chemistry 2001;276(22):19205-13.
2001: Rosamaria Mangiacasale; A Tritarelli; Ilaria Sciamanna; Maria Cannone; Patrizia Lavia; Matteo Barberis; Rodolfo Lorenzini; Enrico Cundari
Normal and cancer-prone human cells respond differently to extremely low frequency magnetic fields.
FEBS letters 2001;487(3):397-403.
2000: Antonella Palena; Rosamaria Mangiacasale; Anna Rosa Magnano; Laura Barberi; Roberto Giordano; Corrado Spadafora; Patrizia Lavia
E2F transcription factors are differentially expressed in murine gametes and early embryos.
Mechanisms of development 2000;97(1-2):211-5.
2000: Pasquale Buanne; Giuseppina Corrente; Laura Micheli; Antonella Palena; Patrizia Lavia; Corrado Spadafora; Madepalli K Lakshmana; A Rinaldi; Sandro Banfi; M Quarto; Alessandro Bulfone; Felice Tirone
Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium.
Genomics 2000;68(3):253-63.
2000: Domenica Taruscio; Grigor K Zoraqi; Mario Falchi; F Iosi; Silvia Paradisi; Barbara Di Fiore; Patrizia Lavia; Vincenzo Falbo
The human per1 gene: genomic organization and promoter analysis of the first human orthologue of the Drosophila period gene.
Gene 2000;253(2):161-70.
2000: Giulia Guarguaglini; Luca Renzi; F D'Ottavio; Barbara Di Fiore; M Casenghi; Enrico Cundari; Patrizia Lavia
Regulated Ran-binding protein 1 activity is required for organization and function of the mitotic spindle in mammalian cells in vivo.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2000;11(8):455-65.
1999: Carmine Pittoggi; Luca Renzi; G Zaccagnini; Daniela Cimini; Francesca Degrassi; Roberto Giordano; Anna Rosa Magnano; Rodolfo Lorenzini; Patrizia Lavia; Corrado Spadafora
A fraction of mouse sperm chromatin is organized in nucleosomal hypersensitive domains enriched in retroposon DNA.
Journal of cell science 1999;112 ( Pt 20)():3537-48.
1999: M Casenghi; Rosamaria Mangiacasale; Marcel Tuynder; P Caillet-Fauquet; Azeddine Elhajouji; Patrizia Lavia; S Mousset; Micheline Kirsch-Volders; Enrico Cundari
p53-independent apoptosis and p53-dependent block of DNA rereplication following mitotic spindle inhibition in human cells.
Experimental cell research 1999;250(2):339-50.
1999: Barbara Di Fiore; Antonella Palena; Armando Felsani; F Palitti; M Caruso; Patrizia Lavia
Cytosine methylation transforms an E2F site in the retinoblastoma gene promoter into a binding site for the general repressor methylcytosine-binding protein 2 (MeCP2).
Nucleic acids research 1999;27(14):2852-9.
1999: Barbara Di Fiore; Giulia Guarguaglini; Antonella Palena; Ron Kerkhoven; René Bernards; Patrizia Lavia
Two E2F sites control growth-regulated and cell cycle-regulated transcription of the Htf9-a/RanBP1 gene through functionally distinct mechanisms.
The Journal of biological chemistry 1999;274(15):10339-48.
1999: Patrizia Lavia; P Jansen-Dürr
E2F target genes and cell-cycle checkpoint control.
BioEssays : news and reviews in molecular, cellular and developmental biology 1999;21(3):221-30.
1998: G Di Matteo; M Salerno; Giulia Guarguaglini; Barbara Di Fiore; F Palitti; Patrizia Lavia
Interactions with single-stranded and double-stranded DNA-binding factors and alternative promoter conformation upon transcriptional activation of the Htf9-a/RanBP1 and Htf9-c genes.
The Journal of biological chemistry 1998;273(1):495-505.
1997: A Battistoni; Giulia Guarguaglini; Francesca Degrassi; Carmine Pittoggi; Antonella Palena; G Di Matteo; Claudio Pisano; Enrico Cundari; Patrizia Lavia
Deregulated expression of the RanBP1 gene alters cell cycle progression in murine fibroblasts.
Journal of cell science 1997;110 ( Pt 19)():2345-57.
1997: Giulia Guarguaglini; A Battistoni; Carmine Pittoggi; G Di Matteo; Barbara Di Fiore; Patrizia Lavia
Expression of the murine RanBP1 and Htf9-c genes is regulated from a shared bidirectional promoter during cell cycle progression.
The Biochemical journal 1997;325 ( Pt 1)():277-86.
1996: D Carotti; S Funiciello; Patrizia Lavia; Paola Caiafa; Roberto Strom
Different effects of histone H1 on de novo DNA methylation in vitro depend on both the DNA base composition and the DNA methyltransferase.
Biochemistry 1996;35(36):11660-7.
1995: G Di Matteo; P Fuschi; K Zerfass; S Moretti; Ruggero Ricordy; C Cenciarelli; M Tripodi; P Jansen-Durr; Patrizia Lavia
Transcriptional control of the Htf9-A/RanBP-1 gene during the cell cycle.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(10):1213-24.
1993: G Stapleton; M P Somma; Patrizia Lavia
Cell type-specific interactions of transcription factors with a housekeeping promoter in vivo.
Nucleic acids research 1993;21(10):2465-71.
1991: M P Somma; I Gambino; Patrizia Lavia
Transcription factors binding to the mouse HTF9 housekeeping promoter differ between cell types.
Nucleic acids research 1991;19(16):4451-8.
1991: A Bressan; M P Somma; J Lewis; C Santolamazza; N G Copeland; D J Gilbert; N A Jenkins; Patrizia Lavia
Characterization of the opposite-strand genes from the mouse bidirectionally transcribed HTF9 locus.
Gene 1991;103(2):201-9.
1991: M P Somma; C Pisano; Patrizia Lavia
The housekeeping promoter from the mouse CpG island HTF9 contains multiple protein-binding elements that are functionally redundant.
Nucleic acids research 1991;19(11):2817-24.
1989: D Carotti; Fabrizio Palitti; Patrizia Lavia; Roberto Strom
In vitro methylation of CpG-rich islands.
Nucleic acids research 1989;17(22):9219-29.
1989: D Carotti; Fabrizio Palitti; C Santolamazza; Patrizia Lavia; Roberto Strom
CpG frequency-dependence in the activity of eukaryotic DNA methyltransferase: in vitro methylation of CpG-rich islands.
The Italian journal of biochemistry 1989;38(6):379A-382A.
1987: Patrizia Lavia; D Macleod; A Bird
Coincident start sites for divergent transcripts at a randomly selected CpG-rich island of mouse.
The EMBO journal 1987;6(9):2773-9.
1985: Patrizia Lavia; M Ferraro; A Micheli; G Olivieri
Effect of 5-azacytidine (5-azaC) on the induction of chromatid aberrations (CA) and sister-chromatid exchanges (SCE).
Mutation research 1985;149(3):463-7.
1985: M Ferraro; Patrizia Lavia
Differential gene activity visualized on sister chromatids after replication in the presence of 5-azacytidine.
Chromosoma 1985;91(3-4):307-12.
1983: M Ferraro; Patrizia Lavia
Activation of human ribosomal genes by 5-azacytidine.
Experimental cell research 1983;145(2):452-7.
1982: M Ferraro; Patrizia Lavia; Franca Pelliccia; Adriana de Capoa
Effects of potassium cyanide on silver stainability of specific cell structures.
Stain technology 1982;57(5):259-63.
1982: Adriana de Capoa; M Ferraro; Patrizia Lavia; Franca Pelliccia; A Finazzi-Agrò
Silver staining of the nucleolus organizer regions (NOR) requires clusters of sulfhydryl groups.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1982;30(9):908-11.
1981: M Ferraro; Patrizia Lavia; Franca Pelliccia; Adriana de Capoa
Clonal inheritance of rRNA gene activity: cytological evidence in human cells.
Chromosoma 1981;84(3):345-51.