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George Nomikos

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Vanessa N Barth; B Giros; S D Gleason; A M Johansson; A B Need; George Nomikos; C Overshiner; K Perry; Eleni T Tzavara; M Wade; Jeffrey M Witkin
In vivo occupancy of dopamine D3 receptors by antagonists produces neurochemical and behavioral effects of potential relevance to attention-deficit-hyperactivity disorder.
Maria Mavrikaki; George Nomikos; George Panagis
Efficacy of the atypical antipsychotic aripiprazole in d-amphetamine-based preclinical models of mania.
Eleni T Tzavara; Aldemar Degroot; Mark R Wade; Richard J Davis; George Nomikos
CB1 receptor knockout mice are hyporesponsive to the behavior-stimulating actions of d-amphetamine: role of mGlu5 receptors.

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2013: Vanessa N Barth; B Giros; S D Gleason; A M Johansson; A B Need; George Nomikos; C Overshiner; K Perry; Eleni T Tzavara; M Wade; Jeffrey M Witkin
In vivo occupancy of dopamine D3 receptors by antagonists produces neurochemical and behavioral effects of potential relevance to attention-deficit-hyperactivity disorder.
The Journal of pharmacology and experimental therapeutics 2013;344(2):501-10.
2010: Maria Mavrikaki; George Nomikos; George Panagis
Efficacy of the atypical antipsychotic aripiprazole in d-amphetamine-based preclinical models of mania.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2010;13(4):541-8.
2009: Eleni T Tzavara; Aldemar Degroot; Mark R Wade; Richard J Davis; George Nomikos
CB1 receptor knockout mice are hyporesponsive to the behavior-stimulating actions of d-amphetamine: role of mGlu5 receptors.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2009;19(3):196-204.
2009: Maria Mavrikaki; George Nomikos; George Panagis
Effects of mood stabilizers on brain reward processes in rats: studies using the intracranial self-stimulation paradigm.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2009;19(3):205-14.
2008: Eleni T Tzavara; Mark R Wade; Richard J Davis; Marie-Anne El Khoury; George Nomikos
Role of metabotropic glutamate receptor 5 in the procholinergic effects of neuropsychotherapeutic compounds.
Synapse (New York, N.Y.) 2008;62(12):940-3.
2008: Styliani Vlachou; Fygaleia Stamatopoulou; George Nomikos; George Panagis
Enhancement of endocannabinoid neurotransmission through CB1 cannabinoid receptors counteracts the reinforcing and psychostimulant effects of cocaine.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2008;11(7):905-23.
2008: Kenneth W Perry; Julie F Falcone; Matthew J Fell; John W Ryder; Hong Yu; Patrick L Love; Jason Katner; Kimberly D Gordon; Mark R Wade; Teresa Man; George Nomikos; Lee A Phebus; Annick J Cauvin; Kirk W Johnson; Carrie K Jones; Beth J Hoffmann; George E Sandusky; Magnus W Walter; Warren J Porter; Lijuan Yang; Kalpana M Merchant; Harlan E Shannon; Kjell A Svensson
Neurochemical and behavioral profiling of the selective GlyT1 inhibitors ALX5407 and LY2365109 indicate a preferential action in caudal vs. cortical brain areas.
Neuropharmacology 2008;55(5):743-54.
2008: Kunrong Cheng; Roxana Samimi; Guofeng Xie; Jasleen Shant; Cinthia Drachenberg; Mark Wade; Richard J Davis; George Nomikos; Jean-Pierre Raufman
Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(3):G591-7.
2008: Katerina Antoniou; Georgia Papathanasiou; Eugenia Papalexi; Thomas Hyphantis; George Nomikos; Christina Spyraki; Zeta Papadopoulou-Daifoti
Individual responses to novelty are associated with differences in behavioral and neurochemical profiles.
Behavioural brain research 2008;187(2):462-72.
2008: R J Davis; George Nomikos
Oral administration of the antiobesity drugs, sibutramine and rimonabant, increases acetylcholine efflux selectively in the medial prefrontal cortex of the rat.
Molecular psychiatry 2008;13(3):240-1.
2008: Christelle Gras; Bénédicte Amilhon; Eve M Lepicard; Odile Poirel; Jacqueline Vinatier; Marc Herbin; Sylvie Dumas; Eleni T Tzavara; Mark R Wade; George Nomikos; Naïma Hanoun; Françoise Saurini; Marie-Louise Kemel; Bruno Gasnier; Bruno GIROS; Salah El Mestikawy
The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone.
Nature neuroscience 2008;11(3):292-300.
2008: Daniel G Smith; Hongshi Qi; Per Svenningsson; Mark Wade; Richard J Davis; Donald R Gehlert; George Nomikos
Behavioral and biochemical responses to d-amphetamine in MCH1 receptor knockout mice.
Synapse (New York, N.Y.) 2008;62(2):128-36.
2007: Styliani Vlachou; George Nomikos; Dai stephens; George Panagis
Lack of evidence for appetitive effects of Delta 9-tetrahydrocannabinol in the intracranial self-stimulation and conditioned place preference procedures in rodents.
Behavioural pharmacology 2007;18(4):311-9.
2007: stephanie weiss; Eleni T Tzavara; Richard J Davis; George Nomikos; J Michael McIntosh; Bruno GIROS; Marie-Pascale Martres
Functional alterations of nicotinic neurotransmission in dopamine transporter knock-out mice.
Neuropharmacology 2007;52(7):1496-508.
2007: Per Svenningsson; Eleni T Tzavara; Hongshi Qi; Robert Carruthers; Jeffrey M Witkin; George Nomikos; Paul Greengard
Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(15):4201-9.
2007: Aldemar Degroot; George Nomikos
In vivo neurochemical effects induced by changes in endocannabinoid neurotransmission.
Current opinion in pharmacology 2007;7(1):62-8.
2006: Mark R Wade; Aldemar Degroot; George Nomikos
Cannabinoid CB1 receptor antagonism modulates plasma corticosterone in rodents.
European journal of pharmacology 2006;551(1-3):162-7.
2006: Susanne H M Gruber; George Nomikos; Aleksander A Mathé
Effects of acute and subchronic d-amphetamine on ventral striatal concentrations of neurotensin and neuropeptide Y in rats treated with antipsychotic drugs.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2006;16(8):592-600.
2006: Daniel G Smith; Richard J Davis; Donald R Gehlert; George Nomikos
Exposure to predator odor stress increases efflux of frontal cortex acetylcholine and monoamines in mice: comparisons with immobilization stress and reversal by chlordiazepoxide.
Brain research 2006;1114(1):24-30.
2006: Styliani Vlachou; George Nomikos; George Panagis
Effects of endocannabinoid neurotransmission modulators on brain stimulation reward.
Psychopharmacology 2006;188(3):293-305.
2006: Aldemar Degroot; Attila Köfalvi; Mark R Wade; Richard J Davis; Ricardo Jorge Rodrigues; Nelson Rebola; Rodrigo A Cunha; George Nomikos
CB1 receptor antagonism increases hippocampal acetylcholine release: site and mechanism of action.
Molecular pharmacology 2006;70(4):1236-45.
2006: Eleni T Tzavara; Frank P Bymaster; George Nomikos
The procholinergic effects of the atypical antipsychotic olanzapine are independent of muscarinic autoreceptor inhibition.
Molecular psychiatry 2006;11(7):619-21.
2006: Amy K Dickason-Chesterfield; Stephanie R Kidd; Steven A Moore; John M Schaus; Bin Liu; George Nomikos; Christian Felder
Pharmacological characterization of endocannabinoid transport and fatty acid amide hydrolase inhibitors.
Cellular and molecular neurobiology 2006;26(4-6):407-23.
2006: Daniel G Smith; Richard J Davis; Linda M Rorick-Kehn; Michelle Morin; Jeffrey M Witkin; David L McKinzie; George Nomikos; Donald R Gehlert
Melanin-concentrating hormone-1 receptor modulates neuroendocrine, behavioral, and corticolimbic neurochemical stress responses in mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(6):1135-45.
2006: Eleni T Tzavara; Dominic L Li; Larissa Moutsimilli; Tiziana Bisogno; Vincenzo Di Marzo; Lee A Phebus; George Nomikos; Bruno GIROS
Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications.
Biological psychiatry 2006;59(6):508-15.
2006: Kelly R Bales; Eleni T Tzavara; Su Wu; Mark R Wade; Frank P Bymaster; Steven M Paul; George Nomikos
Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody.
The Journal of clinical investigation 2006;116(3):825-32.
2006: Aldemar Degroot; George Nomikos
Genetic deletion of muscarinic M4 receptors is anxiolytic in the shock-probe burying model.
European journal of pharmacology 2006;531(1-3):183-6.
2006: Eleni T Tzavara; Frank P Bymaster; C D Overshiner; Richard J Davis; Kenneth W Perry; M Wolff; David L McKinzie; Jeffrey M Witkin; George Nomikos
Procholinergic and memory enhancing properties of the selective norepinephrine uptake inhibitor atomoxetine.
Molecular psychiatry 2006;11(2):187-95.
2006: Per Svenningsson; Karima Chergui; Ilan Rachleff; Marc Flajolet; Xiaoqun Zhang; Malika El Yacoubi; Jean-Marie Vaugeois; George Nomikos; Paul Greengard
Alterations in 5-HT1B receptor function by p11 in depression-like states.
Science (New York, N.Y.) 2006;311(5757):77-80.
2006: Anne B Need; Richard J Davis; Jesline Alexander-Chacko; Brian J Eastwood; Eyassu Chernet; Lee A Phebus; Dana K Sindelar; George Nomikos
The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats.
Psychopharmacology 2006;184(1):26-35.
2005: Steven A Moore; George Nomikos; Amy K Dickason-Chesterfield; Douglas A Schober; John M Schaus; Bai-Ping Ying; Yao-Chang Xu; Lee A Phebus; Rosa Maria A Simmons; D Li; Smriti Iyengar; Christian Felder
Identification of a high-affinity binding site involved in the transport of endocannabinoids.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(49):17852-7.
2005: Jeffrey M Witkin; Eleni T Tzavara; Richard J Davis; Xia Li; George Nomikos
A therapeutic role for cannabinoid CB1 receptor antagonists in major depressive disorders.
Trends in pharmacological sciences 2005;26(12):609-17.
2005: Mark R Wade; George Nomikos
Tolerance to the procholinergic action of the D1 receptor full agonist dihydrexidine.
Psychopharmacology 2005;182(3):393-9.
2005: Jeffrey M Witkin; Eleni T Tzavara; George Nomikos
A role for cannabinoid CB1 receptors in mood and anxiety disorders.
Behavioural pharmacology 2005;16(5-6):315-31.
2005: Aldemar Degroot; Craig Salhoff; Richard J Davis; George Nomikos
Genetic deletion of CB1 receptors improves non-associative learning.
Behavioural brain research 2005;162(1):161-4.
2005: Luciano Minuzzi; George Nomikos; Mark R Wade; Svend B Jensen; Aage Kristian Olsen; Paul Cumming
Interaction between LSD and dopamine D2/3 binding sites in pig brain.
Synapse (New York, N.Y.) 2005;56(4):198-204.
2005: Styliani Vlachou; George Nomikos; George Panagis
CB1 cannabinoid receptor agonists increase intracranial self-stimulation thresholds in the rat.
Psychopharmacology 2005;179(2):498-508.
2005: Aldemar Degroot; George Nomikos
Fluoxetine disrupts the integration of anxiety and aversive memories.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(2):391-400.
2005: Daniel G Smith; Eleni T Tzavara; Janice Shaw; Susan Luecke; Mark Wade; Richard Davis; Craig Salhoff; George Nomikos; Donald R Gehlert
Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(4):914-22.
2005: Aldemar Degroot; Mary C Wolff; George Nomikos
Acute exposure to a novel object during consolidation enhances cognition.
Neuroreport 2005;16(1):63-7.
2004: Eleni T Tzavara; Frank P Bymaster; Richard J Davis; Mark R Wade; Kenneth W Perry; Jürgen Wess; David L McKinzie; Christian Felder; George Nomikos
M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(12):1410-2.
2004: Aldemar Degroot; George Nomikos
Genetic deletion and pharmacological blockade of CB1 receptors modulates anxiety in the shock-probe burying test.
The European journal of neuroscience 2004;20(4):1059-64.
2004: Aldemar Degroot; Mark Wade; Craig Salhoff; Richard J Davis; Eleni T Tzavara; George Nomikos
Exposure to an elevated platform increases plasma corticosterone and hippocampal acetylcholine in the rat: reversal by chlordiazepoxide.
European journal of pharmacology 2004;493(1-3):103-9.
2004: Mark R Wade; Eleni T Tzavara; George Nomikos
Cannabinoids reduce cAMP levels in the striatum of freely moving rats: an in vivo microdialysis study.
Brain research 2004;1005(1-2):117-23.
2004: Katerina Antoniou; Georgia Papathanasiou; George Panagis; George Nomikos; Thomas Hyphantis; Zeta Papadopoulou-Daifoti
Individual responses to novelty predict qualitative differences in d-amphetamine-induced open field but not reward-related behaviors in rats.
Neuroscience 2004;123(3):613-23.
2003: Per Svenningsson; Eleni T Tzavara; Robert Carruthers; Ilan Rachleff; Sigrid Wattler; Michael Nehls; David L McKinzie; Allen Fienberg; George Nomikos; Paul Greengard
Diverse psychotomimetics act through a common signaling pathway.
Science (New York, N.Y.) 2003;302(5649):1412-5.
2003: Kirk W Johnson; Amy Clemens-Smith; George Nomikos; Richard Davis; Lee A Phebus; Harlan Shannon; Patrick Love; Ken Perry; Jason Katner; Frank P Bymaster; Hong Yu; Beth J Hoffman
In vivo characterization of changes in glycine levels induced by GlyT1 inhibitors.
Annals of the New York Academy of Sciences 2003;1003():412-4.
2003: Eleni T Tzavara; Mark Wade; George Nomikos
Biphasic effects of cannabinoids on acetylcholine release in the hippocampus: site and mechanism of action.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(28):9374-84.
2003: Frank P Bymaster; Christian Felder; Eleni T Tzavara; George Nomikos; David O Calligaro; David L McKinzie
Muscarinic mechanisms of antipsychotic atypicality.
Progress in neuro-psychopharmacology & biological psychiatry 2003;27(7):1125-43.
2003: Eleni T Tzavara; Frank P Bymaster; Christian Felder; Mark Wade; Jesus Gomeza; Jürgen Wess; David L McKinzie; George Nomikos
Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice.
Molecular psychiatry 2003;8(7):673-9.
2003: Styliani Vlachou; George Nomikos; George Panagis
WIN 55,212-2 decreases the reinforcing actions of cocaine through CB1 cannabinoid receptor stimulation.
Behavioural brain research 2003;141(2):215-22.
2003: Björn Schilström; Nina Rawal; Monica Mameli-Engvall; George Nomikos; Torgny H Svensson
Dual effects of nicotine on dopamine neurons mediated by different nicotinic receptor subtypes.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2003;6(1):1-11.
2003: Eleni T Tzavara; Richard J Davis; Kenneth W Perry; Xia Li; Craig Salhoff; Frank P Bymaster; Jeffrey M Witkin; George Nomikos
The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions.
British journal of pharmacology 2003;138(4):544-53.
2002: Eleni T Tzavara; Krisztina Monory; Jacques Hanoune; George Nomikos
Nicotine withdrawal syndrome: behavioural distress and selective up-regulation of the cyclic AMP pathway in the amygdala.
The European journal of neuroscience 2002;16(1):149-53.
2002: Susanne H M Gruber; George Nomikos; Aleksander A Mathé
d-Amphetamine-induced increase in neurotensin and neuropeptide Y outflow in the ventral striatum is mediated via stimulation of dopamine D1 and D2/3 receptors.
Journal of neuroscience research 2002;69(1):133-9.
2002: Amy C Porter; John-Michael Sauer; Michael D Knierman; Gerald Becker; Michael J Berna; Jingqi Bao; George Nomikos; Petra Carter; Frank P Bymaster; Andrea Baker Leese; Christian Felder
Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor.
The Journal of pharmacology and experimental therapeutics 2002;301(3):1020-4.
2002: Susanne H M Gruber; George Nomikos; Aleksander A Mathé
Effects of haloperidol and risperidone on neurotensin levels in brain regions and neurotensin efflux in the ventral striatum of the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;26(5):595-604.
2002: Sudabeh Shirazi-Southall; Dana Ellen Rodriguez; George Nomikos
Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;26(5):583-94.
2002: Per Svenningsson; Eleni T Tzavara; Feng Liu; Allen Fienberg; George Nomikos; Paul Greengard
DARPP-32 mediates serotonergic neurotransmission in the forebrain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3188-93.
2002: Per Svenningsson; Eleni T Tzavara; Jeffrey M Witkin; Allen Fienberg; George Nomikos; Paul Greengard
Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac).
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3182-7.
2001: M Iurlo; G Leone; Björn Schilström; L Linnér; George Nomikos; Peter Klaus Hertel; B Silvestrini; H Svensson
Effects of harmine on dopamine output and metabolism in rat striatum: role of monoamine oxidase-A inhibition.
Psychopharmacology 2001;159(1):98-104.
2001: John S Kennedy; Frank P Bymaster; Leslie M Schuh; David O Calligaro; George Nomikos; Christian Felder; M Bernauer; Bruce J Kinon; Robert W Baker; D Hay; H J Roth; Martin Dossenbach; C Kaiser; Charles Beasley; John H Holcombe; M B Effron; Alan Breier
A current review of olanzapine's safety in the geriatric patient: from pre-clinical pharmacology to clinical data.
International journal of geriatric psychiatry 2001;16 Suppl 1():S33-61.
2001: John S Kennedy; A Zagar; Frank P Bymaster; George Nomikos; Paula T Trzepacz; Julie A Gilmore; Matthew D Rotelli; Alan Breier; Gary D Tollefson
The central cholinergic system profile of olanzapine compared with placebo in Alzheimer's disease.
International journal of geriatric psychiatry 2001;16 Suppl 1():S24-32.
2001: Eleni T Tzavara; Kenneth W Perry; D E Rodriguez; Frank P Bymaster; George Nomikos
The cannabinoid CB(1) receptor antagonist SR141716A increases norepinephrine outflow in the rat anterior hypothalamus.
European journal of pharmacology 2001;426(3):R3-4.
2001: Susanne H M Gruber; George Nomikos; Aleksander A Mathé
Dopamine receptor antagonists prevent the d-amphetamine-induced increase in calcitonin gene-related peptide levels in ventral striatum.
Journal of neuroscience research 2001;64(6):606-11.
2001: Monica Marcus; Jan M Mathé; George Nomikos; Torgny H Svensson
Effects of competitive and non-competitive NMDA receptor antagonists on dopamine output in the shell and core subdivisions of the nucleus accumbens.
Neuropharmacology 2001;40(4):482-90.
2001: Peter Klaus Hertel; Nina Lindblom; George Nomikos; Torgny H Svensson
Receptor-mediated regulation of serotonin output in the rat dorsal raphe nucleus: effects of risperidone.
Psychopharmacology 2001;153(3):307-14.
2000: Björn Schilström; MV Fagerquist; X Zhang; Peter Klaus Hertel; George Panagis; George Nomikos; Torgny H Svensson
Putative role of presynaptic alpha7* nicotinic receptors in nicotine stimulated increases of extracellular levels of glutamate and aspartate in the ventral tegmental area.
Synapse (New York, N.Y.) 2000;38(4):375-83.
2000: George Nomikos; S Gruber; Torgny H Svensson; A A Mathé
Effects of acute and chronic electroconvulsive stimuli on cAMP and cGMP efflux in the rat striatum and hippocampus.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2000;10(6):495-500.
2000: Olof Zachrisson; George Nomikos; Monica Marcus; Torgny H Svensson; Nils Lindefors
Effects of antipsychotic drugs on cholecystokinin and preprotachykinin (substance P) mRNA expression in the rat hippocampal formation.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2000;10(5):355-63.
2000: George Nomikos; Björn Schilström; BE Hildebrand; George Panagis; J Grenhoff; Torgny H Svensson
Role of alpha7 nicotinic receptors in nicotine dependence and implications for psychiatric illness.
Behavioural brain research 2000;113(1-2):97-103.
2000: Monica Marcus; George Nomikos; Torgny H Svensson
Effects of atypical antipsychotic drugs on dopamine output in the shell and core of the nucleus accumbens: role of 5-HT(2A) and alpha(1)-adrenoceptor antagonism.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2000;10(4):245-53.
2000: Björn Schilström; Sabina H L de Villiers; A Malmerfelt; Torgny H Svensson; George Nomikos
Nicotine-induced Fos expression in the nucleus accumbens and the medial prefrontal cortex of the rat: role of nicotinic and NMDA receptors in the ventral tegmental area.
Synapse (New York, N.Y.) 2000;36(4):314-21.
2000: George Panagis; Andreas Kastellakis; Christina Spyraki; George Nomikos
Effects of methyllycaconitine (MLA), an alpha 7 nicotinic receptor antagonist, on nicotine- and cocaine-induced potentiation of brain stimulation reward.
Psychopharmacology 2000;149(4):388-96.
2000: George Panagis; BE Hildebrand; Torgny H Svensson; George Nomikos
Selective c-fos induction and decreased dopamine release in the central nucleus of amygdala in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome.
Synapse (New York, N.Y.) 2000;35(1):15-25.
1999: BE Hildebrand; George Panagis; Torgny H Svensson; George Nomikos
Behavioral and biochemical manifestations of mecamylamine-precipitated nicotine withdrawal in the rat: role of nicotinic receptors in the ventral tegmental area.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;21(4):560-74.
1999: Love Linnér; Lotta Arborelius; George Nomikos; L Bertilsson; Torgny H Svensson
Locus coeruleus neuronal activity and noradrenaline availability in the frontal cortex of rats chronically treated with imipramine: effect of alpha 2-adrenoceptor blockade.
Biological psychiatry 1999;46(6):766-74.
1999: Peter Klaus Hertel; George Nomikos; Torgny H Svensson
The antipsychotic drug risperidone interacts with auto- and hetero-receptors regulating serotonin output in the rat frontal cortex.
Neuropharmacology 1999;38(8):1175-84.
1999: P Svenningsson; George Nomikos; Bertil B. Fredholm
The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(10):4011-22.
1999: Peter Klaus Hertel; George Nomikos; Torgny H Svensson
Idazoxan preferentially increases dopamine output in the rat medial prefrontal cortex at the nerve terminal level.
European journal of pharmacology 1999;371(2-3):153-8.
1999: George Nomikos; BE Hildebrand; George Panagis; Torgny H Svensson
Nicotine withdrawal in the rat: role of alpha7 nicotinic receptors in the ventral tegmental area.
Neuroreport 1999;10(4):697-702.
1999: Jan M Mathé; George Nomikos; K H Blakeman; Torgny H Svensson
Differential actions of dizocilpine (MK-801) on the mesolimbic and mesocortical dopamine systems: role of neuronal activity.
Neuropharmacology 1999;38(1):121-8.
1998: Björn Schilström; H M Svensson; Torgny H Svensson; George Nomikos
Nicotine and food induced dopamine release in the nucleus accumbens of the rat: putative role of alpha7 nicotinic receptors in the ventral tegmental area.
Neuroscience 1998;85(4):1005-9.
1998: Peter Klaus Hertel; Nina Lindblom; George Nomikos; Torgny H Svensson
Modulation of central serotonergic neurotransmission by risperidone: underlying mechanism(s) and significance of action.
Progress in neuro-psychopharmacology & biological psychiatry 1998;22(5):815-34.
1998: Jan M Mathé; George Nomikos; Björn Schilström; Torgny H Svensson
Non-NMDA excitatory amino acid receptors in the ventral tegmental area mediate systemic dizocilpine (MK-801) induced hyperlocomotion and dopamine release in the nucleus accumbens.
Journal of neuroscience research 1998;51(5):583-92.
1998: Björn Schilström; George Nomikos; M Nisell; Peter Klaus Hertel; Torgny H Svensson
N-methyl-D-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens.
Neuroscience 1998;82(3):781-9.
1998: Torgny H Svensson; Jan M Mathé; George Nomikos; Björn Schilström
Role of excitatory amino acids in the ventral tegmental area for central actions of non-competitive NMDA-receptor antagonists and nicotine.
Amino acids 1998;14(1-3):51-6.
1998: BE Hildebrand; George Nomikos; Peter Klaus Hertel; Björn Schilström; Torgny H Svensson
Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome.
Brain research 1998;779(1-2):214-25.
1998: Torgny H Svensson; Jan M Mathé; George Nomikos; Björn Schilström; M Marcus; MV Fagerquist
Interactions between catecholamines and serotonin: relevance to the pharmacology of schizophrenia.
Advances in pharmacology (San Diego, Calif.) 1998;42():814-8.
1997: Peter Klaus Hertel; George Nomikos; Torgny H Svensson
Risperidone inhibits 5-hydroxytryptaminergic neuronal activity in the dorsal raphe nucleus by local release of 5-hydroxytryptamine.
British journal of pharmacology 1997;122(8):1639-46.
1997: Karima Chergui; Per Svenningsson; George Nomikos; François Gonon; Bertil B. Fredholm; T H Svennson
Increased expression of NGFI-A mRNA in the rat striatum following burst stimulation of the medial forebrain bundle.
The European journal of neuroscience 1997;9(11):2370-82.
1997: George Nomikos; C S Tham; H C Fibiger; Torgny H Svensson
The putative atypical antipsychotic drug amperozide preferentially increases c-fos expression in rat medial prefrontal cortex and lateral septum.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;17(3):197-201.
1997: M Nisell; George Nomikos; Karima Chergui; Pernilla Grillner; Torgny H Svensson
Chronic nicotine enhances basal and nicotine-induced Fos immunoreactivity preferentially in the medial prefrontal cortex of the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;17(3):151-61.
1997: Per Svenningsson; George Nomikos; Ennio Ongini; Bertil B. Fredholm
Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens.
Neuroscience 1997;79(3):753-64.
1997: Peter Klaus Hertel; George Nomikos; Björn Schilström; Lotta Arborelius; Torgny H Svensson
Risperidone dose-dependently increases extracellular concentrations of serotonin in the rat frontal cortex: role of alpha 2-adrenoceptor antagonism.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;17(1):44-55.
1997: Monica Marcus; George Nomikos; A Malmerfelt; Olof Zachrisson; Nils Lindefors; Torgny H Svensson
Effect of chronic antipsychotic drug treatment on preprosomatostatin and preprotachykinin A mRNA levels in the medial prefrontal cortex, the nucleus accumbens and the caudate putamen of the rat.
Brain research. Molecular brain research 1997;45(2):275-82.
1997: George Panagis; George Nomikos; E Miliaressis; Karima Chergui; Andreas Kastellakis; Torgny H Svensson; Christina Spyraki
Ventral pallidum self-stimulation induces stimulus dependent increase in c-fos expression in reward-related brain regions.
Neuroscience 1997;77(1):175-86.
1997: BE Hildebrand; George Nomikos; C Bondjers; M Nisell; Torgny H Svensson
Behavioral manifestations of the nicotine abstinence syndrome in the rat: peripheral versus central mechanisms.
Psychopharmacology 1997;129(4):348-56.
1997: M Nisell; M Marcus; George Nomikos; Torgny H Svensson
Differential effects of acute and chronic nicotine on dopamine output in the core and shell of the rat nucleus accumbens.
Journal of neural transmission (Vienna, Austria : 1996) 1997;104(1):1-10.
1996: Aleksander A Mathé; Peter Klaus Hertel; George Nomikos; S Gruber; Jan M Mathé; Torgny H Svensson
The psychotomimetic drugs D-amphetamine and phencyclidine release calcitonin gene-related peptide in the limbic forebrain of the rat.
Journal of neuroscience research 1996;46(3):316-23.
1996: George Panagis; M Nisell; George Nomikos; Karima Chergui; Torgny H Svensson
Nicotine injections into the ventral tegmental area increase locomotion and Fos-like immunoreactivity in the nucleus accumbens of the rat.
Brain research 1996;730(1-2):133-42.
1996: Jan M Mathé; George Nomikos; BE Hildebrand; Peter Klaus Hertel; Torgny H Svensson
Prazosin inhibits MK-801-induced hyperlocomotion and dopamine release in the nucleus accumbens.
European journal of pharmacology 1996;309(1):1-11.
1996: Lotta Arborelius; George Nomikos; Peter Klaus Hertel; Peter Salmi; P Grillner; B B Höök; Uli Hacksell; Torgny H Svensson
The 5-HT1A receptor antagonist (S)-UH-301 augments the increase in extracellular concentrations of 5-HT in the frontal cortex produced by both acute and chronic treatment with citalopram.
Naunyn-Schmiedeberg's archives of pharmacology 1996;353(6):630-40.
1996: Karima Chergui; George Nomikos; Jan M Mathé; François Gonon; Torgny H Svensson
Burst stimulation of the medial forebrain bundle selectively increase Fos-like immunoreactivity in the limbic forebrain of the rat.
Neuroscience 1996;72(1):141-56.
1996: M Nisell; George Nomikos; Peter Klaus Hertel; George Panagis; Torgny H Svensson
Condition-independent sensitization of locomotor stimulation and mesocortical dopamine release following chronic nicotine treatment in the rat.
Synapse (New York, N.Y.) 1996;22(4):369-81.
1996: Peter Klaus Hertel; George Nomikos; M Iurlo; Torgny H Svensson
Risperidone: regional effects in vivo on release and metabolism of dopamine and serotonin in the rat brain.
Psychopharmacology 1996;124(1-2):74-86.
1996: M M Marcus; George Nomikos; Torgny H Svensson
Differential actions of typical and atypical antipsychotic drugs on dopamine release in the core and shell of the nucleus accumbens.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1996;6(1):29-38.
1996: George Nomikos; Lotta Arborelius; B B Höök; Uli Hacksell; Torgny H Svensson
The 5-HT1A receptor antagonist (S)-UH-301 decreases dopamine release in the rat nucleus accumbens and striatum.
Journal of neural transmission (Vienna, Austria : 1996) 1996;103(5):541-54.
1995: Peter Klaus Hertel; Jan M Mathé; George Nomikos; M Iurlo; Aleksander A Mathé; Torgny H Svensson
Effects of D-amphetamine and phencyclidine on behavior and extracellular concentrations of neurotensin and dopamine in the ventral striatum and the medial prefrontal cortex of the rat.
Behavioural brain research 1995;72(1-2):103-14.
1995: Per Svenningsson; George Nomikos; Bertil B. Fredholm
Biphasic changes in locomotor behavior and in expression of mRNA for NGFI-A and NGFI-B in rat striatum following acute caffeine administration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(11):7612-24.
1995: J L Andersson; George Nomikos; M Marcus; Peter Klaus Hertel; Jan M Mathé; Torgny H Svensson
Ritanserin potentiates the stimulatory effects of raclopride on neuronal activity and dopamine release selectivity in the mesolimbic dopaminergic system.
Naunyn-Schmiedeberg's archives of pharmacology 1995;352(4):374-85.
1995: Lotta Arborelius; George Nomikos; P Grillner; Peter Klaus Hertel; B B Höök; Uli Hacksell; Torgny H Svensson
5-HT1A receptor antagonists increase the activity of serotonergic cells in the dorsal raphe nucleus in rats treated acutely or chronically with citalopram.
Naunyn-Schmiedeberg's archives of pharmacology 1995;352(2):157-65.
1995: C Wilson; George Nomikos; Maria Collu; HC Fibiger
Dopaminergic correlates of motivated behavior: importance of drive.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(7 Pt 2):5169-78.
1995: N P Kerezoudis; George Nomikos; L M Olgart; Torgny H Svensson
Serotonin in rat oral tissues: role of 5-HT1 receptors in sympathetic vascular control.
European journal of pharmacology 1995;275(2):191-8.
1995: M Nisell; George Nomikos; Torgny H Svensson
Nicotine dependence, midbrain dopamine systems and psychiatric disorders.
Pharmacology & toxicology 1995;76(3):157-62.
1995: Torgny H Svensson; Jan M Mathé; J L Andersson; George Nomikos; BE Hildebrand; M Marcus
Mode of action of atypical neuroleptics in relation to the phencyclidine model of schizophrenia: role of 5-HT2 receptor and alpha 1-adrenoceptor antagonism [corrected].
Journal of clinical psychopharmacology 1995;15(1 Suppl 1):11S-18S.
1994: M Nisell; George Nomikos; Torgny H Svensson
Infusion of nicotine in the ventral tegmental area or the nucleus accumbens of the rat differentially affects accumbal dopamine release.
Pharmacology & toxicology 1994;75(6):348-52.
1994: George Nomikos; Athanasios P Zis; G Damsma; HC Fibiger
Electroconvulsive shock increases interstitial concentrations of uric acid in the rat brain.
Brain research 1994;660(1):50-6.
1994: George Nomikos; M Iurlo; J L Andersson; K Kimura; Torgny H Svensson
Systemic administration of amperozide, a new atypical antipsychotic drug, preferentially increases dopamine release in the rat medial prefrontal cortex.
Psychopharmacology 1994;115(1-2):147-56.
1994: J L Andersson; M Marcus; George Nomikos; Torgny H Svensson
Prazosin modulates the changes in firing pattern and transmitter release induced by raclopride in the mesolimbic, but not in the nigrostriatal dopaminergic system.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(3):236-43.
1994: M Nisell; George Nomikos; Torgny H Svensson
Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area.
Synapse (New York, N.Y.) 1994;16(1):36-44.
1993: S Morgan; George Nomikos; Joseph P Huston
Behavioral analysis of asymmetries induced by unilateral 6-OHDA injections into the substantia nigra.
Behavioral and neural biology 1993;60(3):241-50.
1993: K A McGarvey; Athanasios P Zis; E E Brown; George Nomikos; HC Fibiger
ECS-induced dopamine release: effects of electrode placement, anticonvulsant treatment, and stimulus intensity.
Biological psychiatry 1993;34(3):152-7.
1993: Lotta Arborelius; George Nomikos; Uli Hacksell; Torgny H Svensson
(R)-8-OH-DPAT preferentially increases dopamine release in rat medial prefrontal cortex.
Acta physiologica Scandinavica 1993;148(4):465-6.
1993: Lotta Arborelius; Karima Chergui; S Murase; George Nomikos; B B Höök; Guy Chouvet; Uli Hacksell; Torgny H Svensson
The 5-HT1A receptor selective ligands, (R)-8-OH-DPAT and (S)-UH-301, differentially affect the activity of midbrain dopamine neurons.
Naunyn-Schmiedeberg's archives of pharmacology 1993;347(4):353-62.
1993: A A Mathé; George Nomikos; T H Svensson
In vivo release of somatostatin from rat hippocampus and striatum.
Neuroscience letters 1993;149(2):201-4.
1993: K Kimura; George Nomikos; T H Svensson
Effects of amperozide on psychostimulant-induced hyperlocomotion and dopamine release in the nucleus accumbens.
Pharmacology, biochemistry, and behavior 1993;44(1):27-36.
1992: N P Kerezoudis; L Olgart; L Edwall; B Gazelius; George Nomikos
Activation of sympathetic fibres in the pulp by electrical stimulation of rat incisor teeth.
Archives of oral biology 1992;37(12):1013-9.
1992: Athanasios P Zis; George Nomikos; E E Brown; G Damsma; HC Fibiger
Neurochemical effects of electrically and chemically induced seizures: an in vivo microdialysis study in the rat hippocampus.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1992;7(3):189-95.
1992: T Tanaka; Steven R Vincent; George Nomikos; HC Fibiger
Effect of quinine on autoreceptor-regulated dopamine release in the rat striatum.
Journal of neurochemistry 1992;59(5):1640-5.
1992: K Gradin; F Qadri; George Nomikos; V Hillegaart; Torgny H Svensson
Substance P injection into the dorsal raphe increases blood pressure and serotonin release in hippocampus of conscious rats.
European journal of pharmacology 1992;218(2-3):363-7.
1992: George Nomikos; G Damsma; D Wenkstern; HC Fibiger
Effects of chronic bupropion on interstitial concentrations of dopamine in rat nucleus accumbens and striatum.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1992;7(1):7-14.
1992: George Nomikos; Lotta Arborelius; Torgny H Svensson
The novel 5-HT1A receptor antagonist (S)-UH-301 prevents (R)-8-OH-DPAT-induced decrease in interstitial concentrations of serotonin in the rat hippocampus.
European journal of pharmacology 1992;216(3):373-8.
1992: HC Fibiger; George Nomikos; J G Pfaus; G Damsma
Sexual behavior, eating and mesolimbic dopamine.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():566A-567A.
1992: George Nomikos; Aleksander A Mathé; Jan M Mathé; Torgny H Svensson
MK-801 prevents the enhanced behavioural response to apomorphine elicited by repeated electroconvulsive treatment in mice.
Psychopharmacology 1992;108(3):367-70.
1991: S Morgan; George Nomikos; Joseph P Huston
Changes in the nigrostriatal projection associated with recovery from lesion-induced behavioral asymmetry.
Behavioural brain research 1991;46(2):157-65.
1991: E E Brown; George Nomikos; C Wilson; HC Fibiger
Chronic desipramine enhances the effect of locally applied amphetamine on interstitial concentrations of dopamine in the nucleus accumbens.
European journal of pharmacology 1991;202(1):125-7.
1991: Christina Spyraki; George Nomikos
On the role of serotonin in drug reward: studies with the place conditioning procedure.
Polish journal of pharmacology and pharmacy 1991;43(3):221-9.
1991: George Nomikos; G Damsma; D Wenkstern; HC Fibiger
Chronic desipramine enhances amphetamine-induced increases in interstitial concentrations of dopamine in the nucleus accumbens.
European journal of pharmacology 1991;195(1):63-73.
1991: George Nomikos; Athanasios P Zis; G Damsma; HC Fibiger
Effects of chronic electroconvulsive shock on interstitial concentrations of dopamine in the nucleus accumbens.
Psychopharmacology 1991;105(2):230-8.
1991: Athanasios P Zis; George Nomikos; G Damsma; HC Fibiger
In vivo neurochemical effects of electroconvulsive shock studied by microdialysis in the rat striatum.
Psychopharmacology 1991;103(3):343-50.
1991: George Nomikos; Athanasios P Zis; G Damsma; HC Fibiger
Electroconvulsive shock produces large increases in interstitial concentrations of dopamine in the rat striatum: an in vivo microdialysis study.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1991;4(1):65-9.
1990: J G Pfaus; G Damsma; George Nomikos; D G Wenkstern; Charles D Blaha; Anthony G Phillips; HC Fibiger
Sexual behavior enhances central dopamine transmission in the male rat.
Brain research 1990;530(2):345-8.
1990: George Nomikos; G Damsma; D Wenkstern; HC Fibiger
In vivo characterization of locally applied dopamine uptake inhibitors by striatal microdialysis.
Synapse (New York, N.Y.) 1990;6(1):106-12.
1989: George Nomikos; G Damsma; D Wenkstern; HC Fibiger
Acute effects of bupropion on extracellular dopamine concentrations in rat striatum and nucleus accumbens studied by in vivo microdialysis.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1989;2(4):273-9.
1988: George Nomikos; Christina Spyraki
Effects of ritanserin on the rewarding properties of d-amphetamine, morphine and diazepam revealed by conditioned place preference in rats.
Pharmacology, biochemistry, and behavior 1988;30(4):853-8.
1988: George Nomikos; Christina Spyraki
Influence of oestrogen on spontaneous and diazepam-induced exploration of rats in an elevated plus maze.
Neuropharmacology 1988;27(7):691-6.
1988: Christina Spyraki; George Nomikos; P Galanopoulou; Z Daïfotis
Drug-induced place preference in rats with 5,7-dihydroxytryptamine lesions of the nucleus accumbens.
Behavioural brain research 1988;29(1-2):127-34.
1988: George Nomikos; Christina Spyraki
Cocaine-induced place conditioning: importance of route of administration and other procedural variables.
Psychopharmacology 1988;94(1):119-25.
1987: Christina Spyraki; George Nomikos; D D Varonos
Intravenous cocaine-induced place preference: attenuation by haloperidol.
Behavioural brain research 1987;26(1):57-62.
1987: George Nomikos; Christina Spyraki; A Kazandjian; Anastasia Sfikakis
Estrogen treatment to ovariectomized rats modifies morphine-induced behavior.
Pharmacology, biochemistry, and behavior 1987;27(4):611-7.