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Yuanqing Tang

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Chemicals & Drugs

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Susan A Charman; Sarah Arbe-Barnes; Ian C Bathurst; Reto Brun; Michael Campbell; William N Charman; Francis C K Chiu; Jacques Chollet; J Carl Craft; Darren J Creek; Yuxiang Dong; Hugues Matile; Melanie Maurer; Julia Morizzi; Tien Nguyen; Petros Papastogiannidis; Christian Scheurer; David M Shackleford; Kamaraj Sriraghavan; Lukas Stingelin; Yuanqing Tang; Heinrich Urwyler; Xiaofang Wang; Karen L White; Sergio Wittlin; Lin Zhou; Jonathan L Vennerstrom
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.
Yuanqing Tang; Sergio Wittlin; Susan A Charman; Jacques Chollet; Francis C K Chiu; Julia Morizzi; Lisa M Johnson; Josefina Santo Tomas; Christian Scheurer; Chistopher Snyder; Lin Zhou; Yuxiang Dong; William N Charman; Hugues Matile; Heinrich Urwyler; Arnulf Dorn; Jonathan L Vennerstrom
The comparative antimalarial properties of weak base and neutral synthetic ozonides.
Yuxiang Dong; Sergio Wittlin; Kamaraj Sriraghavan; Jacques Chollet; Susan A Charman; William N Charman; Christian Scheurer; Heinrich Urwyler; Josefina Santo Tomas; Christopher Snyder; Darren J Creek; Julia Morizzi; Maria Koltun; Hugues Matile; Xiaofang Wang; Maniyan Padmanilayam; Yuanqing Tang; Arnulf Dorn; Reto Brun; Jonathan L Vennerstrom
The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).

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All Publications

2011: Susan A Charman; Sarah Arbe-Barnes; Ian C Bathurst; Reto Brun; Michael Campbell; William N Charman; Francis C K Chiu; Jacques Chollet; J Carl Craft; Darren J Creek; Yuxiang Dong; Hugues Matile; Melanie Maurer; Julia Morizzi; Tien Nguyen; Petros Papastogiannidis; Christian Scheurer; David M Shackleford; Kamaraj Sriraghavan; Lukas Stingelin; Yuanqing Tang; Heinrich Urwyler; Xiaofang Wang; Karen L White; Sergio Wittlin; Lin Zhou; Jonathan L Vennerstrom
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(11):4400-5.
2010: Yuanqing Tang; Sergio Wittlin; Susan A Charman; Jacques Chollet; Francis C K Chiu; Julia Morizzi; Lisa M Johnson; Josefina Santo Tomas; Christian Scheurer; Chistopher Snyder; Lin Zhou; Yuxiang Dong; William N Charman; Hugues Matile; Heinrich Urwyler; Arnulf Dorn; Jonathan L Vennerstrom
The comparative antimalarial properties of weak base and neutral synthetic ozonides.
Bioorganic & medicinal chemistry letters 2010;20(2):563-6.
2010: Yuxiang Dong; Sergio Wittlin; Kamaraj Sriraghavan; Jacques Chollet; Susan A Charman; William N Charman; Christian Scheurer; Heinrich Urwyler; Josefina Santo Tomas; Christopher Snyder; Darren J Creek; Julia Morizzi; Maria Koltun; Hugues Matile; Xiaofang Wang; Maniyan Padmanilayam; Yuanqing Tang; Arnulf Dorn; Reto Brun; Jonathan L Vennerstrom
The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).
Journal of medicinal chemistry 2010;53(1):481-91.
2007: Yuanqing Tang; Yuxiang Dong; Sergio Wittlin; Susan A Charman; Jacques Chollet; Francis C K Chiu; William N Charman; Hugues Matile; Heinrich Urwyler; Arnulf Dorn; Saroj Bajpai; Xiaofang Wang; Maniyan Padmanilayam; Jean M Karle; Reto Brun; Jonathan L Vennerstrom
Weak base dispiro-1,2,4-trioxolanes: potent antimalarial ozonides.
Bioorganic & medicinal chemistry letters 2007;17(5):1260-5.
2006: Yuxiang Dong; Yuanqing Tang; Jacques Chollet; Hugues Matile; Sergio Wittlin; Susan A Charman; William N Charman; Josefina Santo Tomas; Christian Scheurer; Christopher Snyder; Bernard Scorneaux; Saroj Bajpai; Scott A Alexander; Xiaofang Wang; Maniyan Padmanilayam; Srinivasa R Cheruku; Reto Brun; Jonathan L Vennerstrom
Effect of functional group polarity on the antimalarial activity of spiro and dispiro-1,2,4-trioxolanes.
Bioorganic & medicinal chemistry 2006;14(18):6368-82.
2005: Yuxiang Dong; Jacques Chollet; Hugues Matile; Susan A Charman; Francis C K Chiu; William N Charman; Bernard Scorneaux; Heinrich Urwyler; Josefina Santo Tomas; Christian Scheurer; Christopher Snyder; Arnulf Dorn; Xiaofang Wang; Jean M Karle; Yuanqing Tang; Sergio Wittlin; Reto Brun; Jonathan L Vennerstrom
Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes.
Journal of medicinal chemistry 2005;48(15):4953-61.
2005: Yuanqing Tang; Yuxiang Dong; Xiaofang Wang; Kamaraj Sriraghavan; James K Wood; Jonathan L Vennerstrom
Dispiro-1,2,4-trioxane analogues of a prototype dispiro-1,2,4-trioxolane: mechanistic comparators for artemisinin in the context of reaction pathways with iron(II).
The Journal of organic chemistry 2005;70(13):5103-10.
2004: Yuanqing Tang; Yuxiang Dong; Jean M Karle; Charles A DiTusa; Jonathan L Vennerstrom
Synthesis of tetrasubstituted ozonides by the Griesbaum coozonolysis reaction: diastereoselectivity and functional group transformations by post-ozonolysis reactions.
The Journal of organic chemistry 2004;69(19):6470-3.
2004: Jonathan L Vennerstrom; Sarah Arbe-Barnes; Reto Brun; Susan A Charman; Francis C K Chiu; Jacques Chollet; Yuxiang Dong; Arnulf Dorn; Daniel Hunziker; Hugues Matile; Kylie McIntosh; Maniyan Padmanilayam; Josefina Santo Tomas; Christian Scheurer; Bernard Scorneaux; Yuanqing Tang; Heinrich Urwyler; Sergio Wittlin; William N Charman
Identification of an antimalarial synthetic trioxolane drug development candidate.
Nature 2004;430(7002):900-4.
2004: Yuanqing Tang; Yuxiang Dong; Jonathan L Vennerstrom
Synthetic peroxides as antimalarials.
Medicinal research reviews 2004;24(4):425-48.