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Donald Kirkpatrick

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Tatiana Goncharov; Anita Izrael-Tomasevic; Donald Kirkpatrick; Kyle Niessen; Eugene Varfolomeev; David Arnott; Maria Cristina de Almagro; Kurt Deshayes; Anna V Fedorova; Domagoj Vucic
OTUB1 modulates c-IAP1 stability to regulate signalling pathways.
Jasmin Dynek; Tatiana Goncharov; Erin C Dueber; Anna V Fedorova; Anita Izrael-Tomasevic; Lilian Phu; Elizabeth Helgason; Wayne J Fairbrother; Kurt Deshayes; Donald Kirkpatrick; Domagoj Vucic
c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling.
John W Blankenship; Eugene Varfolomeev; Tatiana Goncharov; Anna V Fedorova; Donald Kirkpatrick; Anita Izrael-Tomasevic; Lilian Phu; David Arnott; Mariam Aghajan; Kerry Zobel; J. Fernando Bazan; Wayne J Fairbrother; Kurt Deshayes; Domagoj Vucic
Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1).

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All Publications

2013: Tatiana Goncharov; Anita Izrael-Tomasevic; Donald Kirkpatrick; Kyle Niessen; Eugene Varfolomeev; David Arnott; Maria Cristina de Almagro; Kurt Deshayes; Anna V Fedorova; Domagoj Vucic
OTUB1 modulates c-IAP1 stability to regulate signalling pathways.
The EMBO journal 2013;32(8):1103-14.
2010: Jasmin Dynek; Tatiana Goncharov; Erin C Dueber; Anna V Fedorova; Anita Izrael-Tomasevic; Lilian Phu; Elizabeth Helgason; Wayne J Fairbrother; Kurt Deshayes; Donald Kirkpatrick; Domagoj Vucic
c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling.
The EMBO journal 2010;29(24):4198-209.
2009: John W Blankenship; Eugene Varfolomeev; Tatiana Goncharov; Anna V Fedorova; Donald Kirkpatrick; Anita Izrael-Tomasevic; Lilian Phu; David Arnott; Mariam Aghajan; Kerry Zobel; J. Fernando Bazan; Wayne J Fairbrother; Kurt Deshayes; Domagoj Vucic
Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1).
The Biochemical journal 2009;417(1):149-60.
2008: Yulia Matiuhin; Donald Kirkpatrick; Inbal Ziv; Woong Kim; Arun Dakshinamurthy; Oded Kleifeld; Steven P Gygi; Noa Reis; Michael H Glickman
Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome.
Molecular cell 2008;32(3):415-25.
2008: Kim Newton; Marissa L Matsumoto; Ingrid E Wertz; Donald Kirkpatrick; Jennie R Lill; Jenille Tan; Debra Dugger; Nathaniel Gordon; Sachdev S Sidhu; Frederic A Fellouse; Laszlo Komuves; Dorothy M French; Ronald E Ferrando; Cynthia Lam; Deanne Compaan; Christine Yu; Ivan Bosanac; Sarah G Hymowitz; Robert F Kelley; Xiaodong Huang
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell 2008;134(4):668-78.
2008: Marisa J Wainszelbaum; Audra J Charron; Chen Kong; Donald Kirkpatrick; Priya Srikanth; M Alejandro Barbieri; Steven P Gygi; Philip D Stahl
The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking.
The Journal of biological chemistry 2008;283(19):13233-42.
2008: Jeanne Tan; Esther S P Wong; Donald Kirkpatrick; Olga Pletnikova; Han Seok Ko; Shiam-Peng Tay; Michelle W L Ho; Juan C Troncoso; Steven P Gygi; Michael K Lee; Valina Dawson; Ted M Dawson; Kah Leong Lim
Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases.
Human molecular genetics 2008;17(3):431-9.
2007: Jean-François Ménétret; Julia Schaletzky; William M Clemons; Andrew R Osborne; Sigrid S Skånland; Carilee Denison; Steven P Gygi; Donald Kirkpatrick; Eunyong Park; Steven J Ludtke; Tom A Rapoport; Christopher W Akey
Ribosome binding of a single copy of the SecY complex: implications for protein translocation.
Molecular cell 2007;28(6):1083-92.
2007: Maurits F Kleijnen; Donald Kirkpatrick; Steven P Gygi
The ubiquitin-proteasome system regulates membrane fusion of yeast vacuoles.
The EMBO journal 2007;26(2):275-87.
2006: Bernat Crosas; John Hanna; Donald Kirkpatrick; Dan Phoebe Zhang; Yoshiko Tone; Nathaniel A Hathaway; Christa Buecker; David S Leggett; Marion Schmidt; Randall W King; Steven P Gygi; Daniel Finley
Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities.
Cell 2006;127(7):1401-13.
2006: John Hanna; Nathaniel A Hathaway; Yoshiko Tone; Bernat Crosas; Suzanne Elsasser; Donald Kirkpatrick; David S Leggett; Steven P Gygi; Randall W King; Daniel Finley
Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.
Cell 2006;127(1):99-111.
2006: Donald Kirkpatrick; Nathaniel A Hathaway; John Hanna; Suzanne Elsasser; John Rush; Daniel Finley; Randall W King; Steven P Gygi
Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology.
Nature cell biology 2006;8(7):700-10.
2005: Donald Kirkpatrick; Carilee Denison; Steven P Gygi
Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics.
Nature cell biology 2005;7(8):750-7.
2005: Donald Kirkpatrick; Stephen F Weldon; George Tsaprailis; Daniel C Liebler; A Gandolfi
Proteomic identification of ubiquitinated proteins from human cells expressing His-tagged ubiquitin.
Proteomics 2005;5(8):2104-11.
2005: Donald Kirkpatrick; Scott A Gerber; Steven P Gygi
The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications.
Methods (San Diego, Calif.) 2005;35(3):265-73.
2005: Carilee Denison; Donald Kirkpatrick; Steven P Gygi
Proteomic insights into ubiquitin and ubiquitin-like proteins.
Current opinion in chemical biology 2005;9(1):69-75.
2004: Jason Tanny; Donald Kirkpatrick; Scott A Gerber; Steven P Gygi; Danesh Moazed
Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions.
Molecular and cellular biology 2004;24(16):6931-46.
2003: Jeffrey M Catania; Alan R Parrish; Donald Kirkpatrick; M Chitkara; George Bowden; Colin Henderson; C R Wolf; A J Clark; Klaus Brendel; Robyn L Fisher; A Gandolfi
Precision-cut tissue slices from transgenic mice as an in vitro toxicology system.
Toxicology in vitro : an international journal published in association with BIBRA 2003;17(2):201-5.
2003: Donald Kirkpatrick; K V Dale; Jeffrey M Catania; A Gandolfi
Low-level arsenite causes accumulation of ubiquitinated proteins in rabbit renal cortical slices and HEK293 cells.
Toxicology and applied pharmacology 2003;186(2):101-9.