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Miguel Vidal

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David Aguado-Llera; Rosa Doménech; Marco Marenchino; Miguel Vidal; José L Neira
Non-canonical residues of the marginally stable monomeric ubiquitin conjugase from goldfish are involved in binding to the C terminus of Ring 1B.
Kaori Hisada; Haruhiko Koseki; Mónica Román-Trufero; Carmen Sánchez; Jafar Sharif; Takaho A Endo; Mitsuhiro Endoh; Miguel Vidal
RYBP represses endogenous retroviruses and preimplantation- and germ line-specific genes in mouse embryonic stem cells.
Mitsuhiro Endoh; Tamie Endoh; Ragnhild Eskeland; Kyo-ichi Isono; Takashi Ito; Osamu Ohara; Jafar Sharif; Tetsuro Toyoda; Miguel Vidal; Bradley E Bernstein; Wendy A Bickmore; Takaho A Endo; Haruhiko Koseki
Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity.

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2012: David Aguado-Llera; Rosa Doménech; Marco Marenchino; Miguel Vidal; José L Neira
Non-canonical residues of the marginally stable monomeric ubiquitin conjugase from goldfish are involved in binding to the C terminus of Ring 1B.
Biochimica et biophysica acta 2012;1824(8):991-1001.
2012: Kaori Hisada; Haruhiko Koseki; Mónica Román-Trufero; Carmen Sánchez; Jafar Sharif; Takaho A Endo; Mitsuhiro Endoh; Miguel Vidal
RYBP represses endogenous retroviruses and preimplantation- and germ line-specific genes in mouse embryonic stem cells.
Molecular and cellular biology 2012;32(6):1139-49.
2012: Mitsuhiro Endoh; Tamie Endoh; Ragnhild Eskeland; Kyo-ichi Isono; Takashi Ito; Osamu Ohara; Jafar Sharif; Tetsuro Toyoda; Miguel Vidal; Bradley E Bernstein; Wendy A Bickmore; Takaho A Endo; Haruhiko Koseki
Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity.
PLoS genetics 2012;8(7):e1002774.
2009: Mónica Román-Trufero; Hector R. Mendez-Gomez; Claudia Pérez; Atsushi Hijikata; Yu-ichi Fujimura; Takaho Endo; Haruhiko Koseki; Carlos Vicario-Abejón; Miguel Vidal
Maintenance of undifferentiated state and self-renewal of embryonic neural stem cells by Polycomb protein Ring1B.
Stem cells (Dayton, Ohio) 2009;27(7):1559-70.
2009: José L Neira; Mónica Román-Trufero; Lellys M Contreras; Jesús Prieto; Gagandeep Singh; Francisco Barrera; María L Renart; Miguel Vidal
The transcriptional repressor RYBP is a natively unfolded protein which folds upon binding to DNA.
Biochemistry 2009;48(6):1348-60.
2009: Miguel Vidal
Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression.
The International journal of developmental biology 2009;53(2-3):355-70.
2008: Mitsuhiro Endoh; Takaho A Endo; Tamie Endoh; Yu-ichi Fujimura; Osamu Ohara; Tetsuro Toyoda; Arie P Otte; Masaki Okano; Neil Brockdorff; Miguel Vidal; Haruhiko Koseki
Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity.
Development (Cambridge, England) 2008;135(8):1513-24.
2008: Carmela Calés; Mónica Román-Trufero; Leticia Pavón; Iván Serrano; Teresa Melgar; Mitsuhiro Endoh; Claudia Pérez; Haruhiko Koseki; Miguel Vidal
Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion.
Molecular and cellular biology 2008;28(3):1018-28.
2007: Julie K Stock; Sara Giadrossi; Miguel Casanova; Emily Brookes; Miguel Vidal; Haruhiko Koseki; Neil Brockdorff; Amanda G Fisher; Ana Pombo
Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells.
Nature cell biology 2007;9(12):1428-35.
2007: Anna Czypionka; Olga Ruiz de los Paños; Mauricio G Mateu; Francisco Barrera; Estefanía Hurtado-Gómez; Javier Gómez; Miguel Vidal; José L Neira
The isolated C-terminal domain of Ring1B is a dimer made of stable, well-structured monomers.
Biochemistry 2007;46(44):12764-76.
2007: Carmen Sánchez; Inés Sánchez; Jeroen A A Demmers; Patrick Rodriguez; John Strouboulis; Miguel Vidal
Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor.
Molecular & cellular proteomics : MCP 2007;6(5):820-34.
2007: Yuko Kato; Haruhiko Koseki; Miguel Vidal; Hiromitsu Nakauchi; Atsushi Iwama
Unique composition of polycomb repressive complex 1 in hematopoietic stem cells.
International journal of hematology 2007;85(2):179-81.
2006: Yu-ichi Fujimura; Kyo-ichi Isono; Miguel Vidal; Mitsuhiro Endoh; Hiroshi Kajita; Yoko Mizutani-Koseki; Yoshihiro Takihara; Maarten van Lohuizen; Arie Otte; Thomas Jenuwein; Jacqueline Deschamps; Haruhiko Koseki
Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8.
Development (Cambridge, England) 2006;133(12):2371-81.
2006: Laurie A Boyer; Kathrin Plath; Julia Zeitlinger; Tobias Brambrink; Lea A Medeiros; Tong Ihn Lee; Stuart S Levine; Marius Wernig; Adriana Tajonar; Mridula K Ray; George W Bell; Arie P Otte; Miguel Vidal; David K Gifford; Richard A Young; Rudolf Jaenisch
Polycomb complexes repress developmental regulators in murine embryonic stem cells.
Nature 2006;441(7091):349-53.
2006: Margarita Sánchez-Beato; Esther Sánchez; Joaquín González-Carreró; Manuel Morente; Ana Díez; Lydia Sánchez-Verde; María Carmen Martín; Juan C Cigudosa; Miguel Vidal; Miguel A Piris
Variability in the expression of polycomb proteins in different normal and tumoral tissues. A pilot study using tissue microarrays.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006;19(5):684-94.
2006: Mar Lorente; Claudia Pérez; Carmen Sánchez; Mary Donohoe; Yang Shi; Miguel Vidal
Homeotic transformations of the axial skeleton of YY1 mutant mice and genetic interaction with the Polycomb group gene Ring1/Ring1A.
Mechanisms of development 2006;123(4):312-20.
2005: Fernando Bejarano; Inma González; Miguel Vidal; Ana Busturia
The Drosophila RYBP gene functions as a Polycomb-dependent transcriptional repressor.
Mechanisms of development 2005;122(10):1118-29.
2004: Margarita Sánchez-Beato; Esther Sánchez; Juan F García; Alberto Pérez-Rosado; María C Montoya; Máximo Fraga; María-Jesús Artiga; Mercedes Navarrete; Víctor Abraira; Manuel Morente; Manel Esteller; Haruhiko Koseki; Miguel Vidal; Miguel A Piris
Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFkappaB transcription factors.
The Journal of pathology 2004;204(5):528-37.
2004: Mariana de Napoles; Jacqueline E Mermoud; Rika Wakao; Y Amy Tang; Mitusuhiro Endoh; Ruth Appanah; Tatyana B Nesterova; Jose Silva; Arie P Otte; Miguel Vidal; Haruhiko Koseki; Neil Brockdorff
Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.
Developmental cell 2004;7(5):663-76.
2004: Hengbin Wang; Liangjun Wang; Hediye Erdjument-Bromage; Miguel Vidal; Paul Tempst; Richard S Jones; Yi Zhang
Role of histone H2A ubiquitination in Polycomb silencing.
Nature 2004;431(7010):873-8.
2004: Nicole Gorfinkiel; Laura Fanti; Teresa Melgar; Emiliano García; Sergio Pimpinelli; Isabel Guerrero; Miguel Vidal
The Drosophila Polycomb group gene Sex combs extra encodes the ortholog of mammalian Ring1 proteins.
Mechanisms of development 2004;121(5):449-62.
2003: Hiro Miyagishima; Kyo-ichi Isono; Yuichi Fujimura; Masaomi Iyo; Yoshihiro Takihara; Hiroshi Masumoto; Miguel Vidal; Haruhiko Koseki
Dissociation of mammalian Polycomb-group proteins, Ring1B and Rae28/Ph1, from the chromatin correlates with configuration changes of the chromatin in mitotic and meiotic prophase.
Histochemistry and cell biology 2003;120(2):111-9.
2002: Suzanne Schlisio; Terri Halperin; Miguel Vidal; Joseph R Nevins
Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function.
The EMBO journal 2002;21(21):5775-86.
2002: Maki Suzuki; Yoko Mizutani-Koseki; Yu-Ichi Fujimura; Hiro Miyagishima; Tomomi Kaneko; Yuki Takada; Takeshi Akasaka; Hideki Tanzawa; Yoshihiro Takihara; Megumi Nakano; Hiroshi Masumoto; Miguel Vidal; Kyo-ichi Isono; Haruhiko Koseki
Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice.
Development (Cambridge, England) 2002;129(18):4171-83.
2001: Bettina Peters; Jutta Kirfel; Heinrich Büssow; Miguel Vidal; Thomas M Magin
Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex.
Molecular biology of the cell 2001;12(6):1775-89.
2001: A Ramírez; E Milot; Immaculada Ponsa; C Marcos-Gutiérrez; A Page; M Santos; J Jorcano; Miguel Vidal
Sequence and chromosomal context effects on variegated expression of keratin 5/lacZ constructs in stratified epithelia of transgenic mice.
Genetics 2001;158(1):341-50.
2001: Takeshi Akasaka; Maarten van Lohuizen; NM Van der Lugt; Yoko Mizutani-Koseki; M Kanno; Masaru Taniguchi; Miguel Vidal; MJ Alkema; Anton Berns; Haruhiko Koseki
Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression.
Development (Cambridge, England) 2001;128(9):1587-97.
2001: T Atsuta; S Fujimura; H Moriya; Miguel Vidal; T Akasaka; H Koseki
Production of monoclonal antibodies against mammalian Ring1B proteins.
Hybridoma 2001;20(1):43-6.
2000: M del Mar Lorente; C Marcos-Gutiérrez; C Pérez; J Schoorlemmer; A Ramírez; T Magin; Miguel Vidal
Loss- and gain-of-function mutations show a polycomb group function for Ring1A in mice.
Development (Cambridge, England) 2000;127(23):5093-100.
1999: E García; C Marcos-Gutiérrez; M del Mar Lorente; J C Moreno; Miguel Vidal
RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1.
The EMBO journal 1999;18(12):3404-18.
1999: M Llanos Casanova; A Bravo; A Ramírez; G Morreale de Escobar; F Were; G Merlino; Miguel Vidal; José L Jorcano
Exocrine pancreatic disorders in transsgenic mice expressing human keratin 8.
The Journal of clinical investigation 1999;103(11):1587-95.
1997: J Schoorlemmer; C Marcos-Gutiérrez; F Were; R Martínez; E García; David P E Satijn; A P Otte; Miguel Vidal
Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain.
The EMBO journal 1997;16(19):5930-42.
1995: A Ramírez; Miguel Vidal; A Bravo; F Larcher; José L Jorcano
A 5'-upstream region of a bovine keratin 6 gene confers tissue-specific expression and hyperproliferation-related induction in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4783-7.
1995: L Casanova; A Bravo; F Were; A Ramírez; J J Jorcano; Miguel Vidal
Tissue-specific and efficient expression of the human simple epithelial keratin 8 gene in transgenic mice.
Journal of cell science 1995;108 ( Pt 2)():811-20.
1994: A Ramírez; A Bravo; José L Jorcano; Miguel Vidal
Sequences 5' of the bovine keratin 5 gene direct tissue- and cell-type-specific expression of a lacZ gene in the adult and during development.
Differentiation; research in biological diversity 1994;58(1):53-64.