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Wolf-Dieter Schubert

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Jürgen Moser; Johannes Rebelein; Markus W Ribbe; Wolf-Dieter Schubert; Dirk W Heinz; Joern Krausze; Christiane Lange; Dieter Jahn
Structure of ADP-aluminium fluoride-stabilized protochlorophyllide oxidoreductase complex.
Markus J Bröcker; Sebastian Schomburg; Dirk W Heinz; Dieter Jahn; Wolf-Dieter Schubert; Jürgen Moser
Crystal structure of the nitrogenase-like dark operative protochlorophyllide oxidoreductase catalytic complex (ChlN/ChlB)2.
Ilka U Heinemann; Claudia Schulz; Wolf-Dieter Schubert; Dirk W Heinz; Yang-G Wang; Yuichi Kobayashi; Yuuki Awa; Masaaki Wachi; Dieter Jahn; Martina Jahn
Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin.

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All Publications

2013: Jürgen Moser; Johannes Rebelein; Markus W Ribbe; Wolf-Dieter Schubert; Dirk W Heinz; Joern Krausze; Christiane Lange; Dieter Jahn
Structure of ADP-aluminium fluoride-stabilized protochlorophyllide oxidoreductase complex.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(6):2094-8.
2010: Markus J Bröcker; Sebastian Schomburg; Dirk W Heinz; Dieter Jahn; Wolf-Dieter Schubert; Jürgen Moser
Crystal structure of the nitrogenase-like dark operative protochlorophyllide oxidoreductase catalytic complex (ChlN/ChlB)2.
The Journal of biological chemistry 2010;285(35):27336-45.
2010: Ilka U Heinemann; Claudia Schulz; Wolf-Dieter Schubert; Dirk W Heinz; Yang-G Wang; Yuichi Kobayashi; Yuuki Awa; Masaaki Wachi; Dieter Jahn; Martina Jahn
Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin.
Antimicrobial agents and chemotherapy 2010;54(1):267-72.
2009: Maike Bublitz; Lilia Polle; Christin Holland; Dirk W Heinz; Manfred Nimtz; Wolf-Dieter Schubert
Structural basis for autoinhibition and activation of Auto, a virulence-associated peptidoglycan hydrolase of Listeria monocytogenes.
Molecular microbiology 2009;71(6):1509-22.
2009: Gregor Hagelueken; Simone C Albrecht; Heinrich Steinmetz; Rolf Jansen; Dirk W Heinz; Markus Kalesse; Wolf-Dieter Schubert
The absolute configuration of rhizopodin and its inhibition of actin polymerization by dimerization.
Angewandte Chemie (International ed. in English) 2009;48(3):595-8.
2008: Maike Bublitz; Christin Holland; Christophe Sabet; Joachim Reichelt; Pascale Cossart; Dirk W Heinz; Helene bierne; Wolf-Dieter Schubert
Crystal structure and standardized geometric analysis of InlJ, a listerial virulence factor and leucine-rich repeat protein with a novel cysteine ladder.
Journal of molecular biology 2008;378(1):87-96.
2008: Markus J Bröcker; Simone Virus; Stefanie Ganskow; Peter Heathcote; Dirk W Heinz; Wolf-Dieter Schubert; Dieter Jahn; Jürgen Moser
ATP-driven reduction by dark-operative protochlorophyllide oxidoreductase from Chlorobium tepidum mechanistically resembles nitrogenase catalysis.
The Journal of biological chemistry 2008;283(16):10559-67.
2007: Corinna Lüer; Stefan Schauer; Simone Virus; Wolf-Dieter Schubert; Dirk W Heinz; Jürgen Moser; Dieter Jahn
Glutamate recognition and hydride transfer by Escherichia coli glutamyl-tRNA reductase.
The FEBS journal 2007;274(17):4609-14.
2007: Thomas Wollert; Dirk W Heinz; Wolf-Dieter Schubert
Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):13960-5.
2007: Gregor Hagelueken; Lutz Wiehlmann; Thorsten M Adams; Harald Kolmar; Dirk W Heinz; Burkhard Tümmler; Wolf-Dieter Schubert
Crystal structure of the electron transfer complex rubredoxin rubredoxin reductase of Pseudomonas aeruginosa.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(30):12276-81.
2007: Thomas Wollert; Bastian Pasche; Maike Rochon; Stefanie Deppenmeier; Joop van den Heuvel; Achim D Gruber; Dirk W Heinz; Andreas Lengeling; Wolf-Dieter Schubert
Extending the host range of Listeria monocytogenes by rational protein design.
Cell 2007;129(5):891-902.
2006: Jörg O Schulze; Ava Masoumi; Daniel Nickel; Martina Jahn; Dieter Jahn; Wolf-Dieter Schubert; Dirk W Heinz
Crystal structure of a non-discriminating glutamyl-tRNA synthetase.
Journal of molecular biology 2006;361(5):888-97.
2006: Susanne Frese; Wolf-Dieter Schubert; Antje C Findeis; Tobias Marquardt; Yvette S Roske; Theresia E B Stradal; Dirk W Heinz
The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.
The Journal of biological chemistry 2006;281(26):18236-45.
2006: Jörg O Schulze; Wolf-Dieter Schubert; Jürgen Moser; Dieter Jahn; Dirk W Heinz
Evolutionary relationship between initial enzymes of tetrapyrrole biosynthesis.
Journal of molecular biology 2006;358(5):1212-20.
2006: Gregor Hagelueken; Thorsten M Adams; Lutz Wiehlmann; Ute Widow; Harald Kolmar; Burkhard Tümmler; Dirk W Heinz; Wolf-Dieter Schubert
The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7631-6.
2005: Gunhild Layer; Eric Kervio; Gaby Morlock; Dirk W Heinz; Dieter Jahn; Janos Retey; Wolf-Dieter Schubert
Structural and functional comparison of HemN to other radical SAM enzymes.
Biological chemistry 2005;386(10):971-80.
2005: Isabel Astner; Jörg O Schulze; Joop van den Heuvel; Dieter Jahn; Wolf-Dieter Schubert; Dirk W Heinz
Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans.
The EMBO journal 2005;24(18):3166-77.
2005: Corinna Lüer; Stefan Schauer; Kalle Möbius; Jörg O Schulze; Wolf-Dieter Schubert; Dirk W Heinz; Dieter Jahn; Jürgen Moser
Complex formation between glutamyl-tRNA reductase and glutamate-1-semialdehyde 2,1-aminomutase in Escherichia coli during the initial reactions of porphyrin biosynthesis.
The Journal of biological chemistry 2005;280(19):18568-72.
2005: Marina Eiting; Gregor Hagelüken; Wolf-Dieter Schubert; Dirk W Heinz
The mutation G145S in PrfA, a key virulence regulator of Listeria monocytogenes, increases DNA-binding affinity by stabilizing the HTH motif.
Molecular microbiology 2005;56(2):433-46.
2005: Dirk W Heinz; Wolf-Dieter Schubert; Gerhard Höfle
Much anticipated--the bioactive conformation of epothilone and its binding to tubulin.
Angewandte Chemie (International ed. in English) 2005;44(9):1298-301.
2005: Frederic Frère; Heike Reents; Wolf-Dieter Schubert; Dirk W Heinz; Dieter Jahn
Tracking the evolution of porphobilinogen synthase metal dependence in vitro.
Journal of molecular biology 2005;345(5):1059-70.
2005: Ulrike Fock; Brigitte M Jockusch; Wolf-Dieter Schubert; Horst Hinssen
Topological assignment of the N-terminal extension of plasma gelsolin to the gelsolin surface.
The Biochemical journal 2005;385(Pt 3):659-65.
2004: Stefanie Ehinger; Wolf-Dieter Schubert; Simone Bergmann; Sven Hammerschmidt; Dirk W Heinz
Plasmin(ogen)-binding alpha-enolase from Streptococcus pneumoniae: crystal structure and evaluation of plasmin(ogen)-binding sites.
Journal of molecular biology 2004;343(4):997-1005.
2004: Gunhild Layer; Dirk W Heinz; Dieter Jahn; Wolf-Dieter Schubert
Structure and function of radical SAM enzymes.
Current opinion in chemical biology 2004;8(5):468-76.
2004: Alexander Freiberg; Matthias Machner; Wolfgang Pfeil; Wolf-Dieter Schubert; Dirk W Heinz; Robert Seckler
Folding and stability of the leucine-rich repeat domain of internalin B from Listeri monocytogenes.
Journal of molecular biology 2004;337(2):453-61.
2004: Hartmut H Niemann; Wolf-Dieter Schubert; Dirk W Heinz
Adhesins and invasins of pathogenic bacteria: a structural view.
Microbes and infection / Institut Pasteur 2004;6(1):101-12.
2003: Wolf-Dieter Schubert; Dirk W Heinz
Structural aspects of adhesion to and invasion of host cells by the human pathogen Listeria monocytogenes.
Chembiochem : a European journal of chemical biology 2003;4(12):1285-91.
2003: Gunhild Layer; Jürgen Moser; Dirk W Heinz; Dieter Jahn; Wolf-Dieter Schubert
Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes.
The EMBO journal 2003;22(23):6214-24.
2003: Matthias Machner; Susanne Frese; Wolf-Dieter Schubert; Veronique Orian-Rousseau; Ermanno Gherardi; Jürgen Wehland; Hartmut H Niemann; Dirk W Heinz
Aromatic amino acids at the surface of InlB are essential for host cell invasion by Listeria monocytogenes.
Molecular microbiology 2003;48(6):1525-36.
2002: Wolf-Dieter Schubert; Claus Urbanke; Thilo Ziehm; Viola Beier; Matthias Machner; Eugen Domann; Jürgen Wehland; Trinad Chakraborty; Dirk W Heinz
Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin.
Cell 2002;111(6):825-36.
2002: Stefan Schauer; Shalini Chaturvedi; Lennart Randau; Jürgen Moser; Makoto Kitabatake; Stefan Lorenz; Elizabeth Verkamp; Wolf-Dieter Schubert; Toru Nakayashiki; Masatoshi Murai; Kristen Wall; Hans-Ulrich Thomann; Dirk W Heinz; Hachiro Inokuchi; Dieter Söll; Dieter Jahn
Escherichia coli glutamyl-tRNA reductase. Trapping the thioester intermediate.
The Journal of biological chemistry 2002;277(50):48657-63.
2002: Jürgen Moser; Wolf-Dieter Schubert; Dirk W Heinz; Dieter Jahn
Structure and function of glutamyl-tRNA reductase involved in 5-aminolaevulinic acid formation.
Biochemical Society transactions 2002;30(4):579-84.
2002: Frederic Frère; Wolf-Dieter Schubert; Frédéric Stauffer; Nicole Frankenberg; Reinhard Neier; Dieter Jahn; Dirk W Heinz
Structure of porphobilinogen synthase from Pseudomonas aeruginosa in complex with 5-fluorolevulinic acid suggests a double Schiff base mechanism.
Journal of molecular biology 2002;320(2):237-47.
2001: Jürgen Moser; Wolf-Dieter Schubert; V Beier; I Bringemeier; Dieter Jahn; Dirk W Heinz
V-shaped structure of glutamyl-tRNA reductase, the first enzyme of tRNA-dependent tetrapyrrole biosynthesis.
The EMBO journal 2001;20(23):6583-90.
2001: Kazuaki Harata; Wolf-Dieter Schubert; muraki michiro
Structure of Urtica dioica agglutinin isolectin I: dimer formation mediated by two zinc ions bound at the sugar-binding site.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 11):1513-7.
2001: Wolf-Dieter Schubert; G Göbel; M Diepholz; Ayub Darji; D Kloer; Torsten Hain; Trinad Chakraborty; Jürgen Wehland; Eugen Domann; Dirk W Heinz
Internalins from the human pathogen Listeria monocytogenes combine three distinct folds into a contiguous internalin domain.
Journal of molecular biology 2001;312(4):783-94.
2001: M Barzik; Uwe D Carl; Wolf-Dieter Schubert; R Frank; Jürgen Wehland; Dirk W Heinz
The N-terminal domain of Homer/Vesl is a new class II EVH1 domain.
Journal of molecular biology 2001;309(1):155-69.
2000: M Barzik; Wolf-Dieter Schubert; Uwe D Carl; Jürgen Wehland; Dirk W Heinz
Crystallization and preliminary X-ray analysis of the EVH1 domain of Vesl-2b.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 7):930-2.
1999: O Klukas; Wolf-Dieter Schubert; Patrick Jordan; N Krau; Petra Fromme; Heike Witt; Wolfram Saenger
Localization of two phylloquinones, QK and QK', in an improved electron density map of photosystem I at 4-A resolution.
The Journal of biological chemistry 1999;274(11):7361-7.
1999: O Klukas; Wolf-Dieter Schubert; Patrick Jordan; Norbert Krauss; Petra Fromme; Heike Witt; Wolfram Saenger
Photosystem I, an improved model of the stromal subunits PsaC, PsaD, and PsaE.
The Journal of biological chemistry 1999;274(11):7351-60.
1998: Wolf-Dieter Schubert; O Klukas; Wolfram Saenger; Heike Witt; Petra Fromme; Norbert Krauss
A common ancestor for oxygenic and anoxygenic photosynthetic systems: a comparison based on the structural model of photosystem I.
Journal of molecular biology 1998;280(2):297-314.
1997: Wolf-Dieter Schubert; O Klukas; Norbert Krauss; Wolfram Saenger; Petra Fromme; Heike Witt
Photosystem I of Synechococcus elongatus at 4 A resolution: comprehensive structure analysis.
Journal of molecular biology 1997;272(5):741-69.
1997: A Kamlowski; Art van der Est; Petra Fromme; Norbert Krauss; Wolf-Dieter Schubert; O Klukas; Dietmar Stehlik
The structural organization of the PsaC protein in Photosystem I from single crystal EPR and X-ray crystallographic studies.
Biochimica et biophysica acta 1997;1319(2-3):199-213.
1996: Norbert Krauss; Wolf-Dieter Schubert; O Klukas; Petra Fromme; Heike Witt; Wolfram Saenger
Photosystem I at 4 A resolution represents the first structural model of a joint photosynthetic reaction centre and core antenna system.
Nature structural biology 1996;3(11):965-73.
1994: Wolf-Dieter Schubert; G Schluckebier; Jan Backmann; Joachim Granzin; Caroline Kisker; Hui-Woog Choe; Ulrich Hahn; W Pfeil; Wolfram Saenger
X-ray crystallographic and calorimetric studies of the effects of the mutation Trp59-->Tyr in ribonuclease T1.
European journal of biochemistry / FEBS 1994;220(2):527-34.