FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

H White

Research Profile

Chemicals & Drugs

Living Beings

Disorders

Anatomy

Procedures

Concepts & Ideas

Drug Dose Response Relationship

Co-author Network

Publications

TOP 3
Brad R Green; Karen L White; Daniel R McDougle; Liuyin Zhang; Brian Klein; Erika Adkins Scholl; Timothy H Pruess; H White; Grzegorz Bulaj
Introduction of lipidization-cationization motifs affords systemically bioavailable neuropeptide Y and neurotensin analogs with anticonvulsant activities.
Jane E Libbey; Nikki J Kirkman; Karen S Wilcox; H White; Robert S Fujinami
Role for complement in the development of seizures following acute viral infection.
Karsten K Madsen; H White; Arne Schousboe
Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of H White (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2010: Brad R Green; Karen L White; Daniel R McDougle; Liuyin Zhang; Brian Klein; Erika Adkins Scholl; Timothy H Pruess; H White; Grzegorz Bulaj
Introduction of lipidization-cationization motifs affords systemically bioavailable neuropeptide Y and neurotensin analogs with anticonvulsant activities.
Journal of peptide science : an official publication of the European Peptide Society 2010;16(9):486-95.
2010: Jane E Libbey; Nikki J Kirkman; Karen S Wilcox; H White; Robert S Fujinami
Role for complement in the development of seizures following acute viral infection.
Journal of virology 2010;84(13):6452-60.
2010: Karsten K Madsen; H White; Arne Schousboe
Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs.
Pharmacology & therapeutics 2010;125(3):394-401.
2010: Nikki J Kirkman; Jane E Libbey; Karen S Wilcox; H White; Robert S Fujinami
Innate but not adaptive immune responses contribute to behavioral seizures following viral infection.
Epilepsia 2010;51(3):454-64.
2010: Charles R Robertson; Erika Adkins Scholl; Timothy H Pruess; Brad R Green; H White; Grzegorz Bulaj
Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery.
Journal of medicinal chemistry 2010;53(4):1871-5.
2010: Meir Bialer; H White
Key factors in the discovery and development of new antiepileptic drugs.
Nature reviews. Drug discovery 2010;9(1):68-82.
2009: Michael H Parker; Virginia L Smith-Swintosky; David F McComsey; Yifang Huang; Douglas Brenneman; Brian Klein; Ewa Malatynska; H White; Michael E Milewski; Mark Herb; Michael F A Finley; Yi Liu; Mary Lou Lubin; Ning Qin; Robert Iannucci; Laurent Leclercq; Filip Cuyckens; Allen B Reitz; Bruce E Maryanoff
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
Journal of medicinal chemistry 2009;52(23):7528-36.
2009: K D Statler; P Scheerlinck; W Pouliot; M Hamilton; H White; F Edward Dudek
A potential model of pediatric posttraumatic epilepsy.
Epilepsy research 2009;86(2-3):221-3.
2009: Nanda A Singh; Chris Pappas; E Jill Dahle; Lieve R F Claes; Timothy H Pruess; Peter De Jonghe; Joel Thompson; Missy Dixon; Christina Gurnett; Andy P Peiffer; H White; Francis M Filloux; Mark F Leppert
A role of SCN9A in human epilepsies, as a cause of febrile seizures and as a potential modifier of Dravet syndrome.
PLoS genetics 2009;5(9):e1000649.
2009: Hee-Kyoung Lee; Misty Smith; Brian J Smith; Joel Grussendorf; Liping Xu; Robert J Gillies; H White; Grzegorz Bulaj
Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain.
ACS chemical biology 2009;4(8):659-71.
2009: James F Otto; Nanda A Singh; E Jill Dahle; Mark F Leppert; Chris M Pappas; Timothy H Pruess; Karen S Wilcox; H White
Electroconvulsive seizure thresholds and kindling acquisition rates are altered in mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions.
Epilepsia 2009;50(7):1752-9.
2009: Karsten K Madsen; Rasmus P Clausen; Orla M Larsson; Povl Krogsgaard-Larsen; Arne Schousboe; H White
Synaptic and extrasynaptic GABA transporters as targets for anti-epileptic drugs.
Journal of neurochemistry 2009;109 Suppl 1():139-44.
2009: H White; Erika Adkins Scholl; Brian D Klein; Sean P Flynn; Timothy H Pruess; Brad R Green; Liuyin Zhang; Grzegorz Bulaj
Developing novel antiepileptic drugs: characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2009;6(2):372-80.
2009: Liuyin Zhang; Hee-Kyoung Lee; Timothy H Pruess; H White; Grzegorz Bulaj
Synthesis and applications of polyamine amino acid residues: improving the bioactivity of an analgesic neuropeptide, neurotensin.
Journal of medicinal chemistry 2009;52(6):1514-7.
2009: Liuyin Zhang; Charles R Robertson; Brad R Green; Timothy H Pruess; H White; Grzegorz Bulaj
Structural requirements for a lipoamino acid in modulating the anticonvulsant activities of systemically active galanin analogues.
Journal of medicinal chemistry 2009;52(5):1310-6.
2009: Hee-Kyoung Lee; Liuyin Zhang; Misty Smith; H White; Grzegorz Bulaj
Glycosylated neurotensin analogues exhibit sub-picomolar anticonvulsant potency in a pharmacoresistant model of epilepsy.
ChemMedChem 2009;4(3):400-5.
2009: David C Henshall; Nick Dürmüller; H White; Robert Williams; Paul Moser; Mark Dunleavy; Peter H Silverstone
Electroencephalographic and behavioral convulsant effects of hydrobromide and hydrochloride salts of bupropion in conscious rodents.
Neuropsychiatric disease and treatment 2009;5():189-206.
2009: Meir Bialer; Svein I Johannessen; René H Levy; Emilio Perucca; Torbjörn Tomson; H White
Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX).
Epilepsy research 2009;83(1):1-43.
2008: Kimberly D Statler; Seth Swank; Tracy Abildskov; Erin D Bigler; H White
Traumatic brain injury during development reduces minimal clonic seizure thresholds at maturity.
Epilepsy research 2008;80(2-3):163-70.
2008: H White; Michael R Franklin; Harvey J Kupferberg; Markus Schmutz; James P Stables; HH Wolf
The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models.
Epilepsia 2008;49(7):1213-20.
2008: Mark Foreman; Taleen Hanania; Sharon C Stratton; Karen S Wilcox; H White; James P Stables; Mark Eller
In vivo pharmacological effects of JZP-4, a novel anticonvulsant, in models for anticonvulsant, antimania and antidepressant activity.
Pharmacology, biochemistry, and behavior 2008;89(4):523-34.
2008: Jane E Libbey; Nikki J Kirkman; Matthew C P Smith; Tomoko Tanaka; Karen S Wilcox; H White; Robert S Fujinami
Seizures following picornavirus infection.
Epilepsia 2008;49(6):1066-74.
2008: Misty Smith; Gerald W Saunders; Rasmus P Clausen; Bente Frølund; Povl Krogsgaard-Larsen; Orla M Larsson; Arne Schousboe; Karen S Wilcox; H White
Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC).
Epilepsy research 2008;79(1):6-13.
2008: Kimberly D Statler; Seth Swank; H White
Strain and age affect electroconvulsive seizure testing in rats.
Epilepsy research 2008;78(2-3):232-4.
2007: Thomas Stoehr; Harvey J Kupferberg; James P Stables; Daeock Choi; Robert H Harris; Harold Kohn; Nancy Walton; H White
Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy.
Epilepsy research 2007;74(2-3):147-54.
2007: Misty Smith; Amy C Adams; Gerald W Saunders; H White; Karen S Wilcox
Phenytoin- and carbamazepine-resistant spontaneous bursting in rat entorhinal cortex is blocked by retigabine in vitro.
Epilepsy research 2007;74(2-3):97-106.
2007: Paul W Lenkowski; Timothy W Batts; Misty Smith; Seong-Hoon Ko; Paulianda J Jones; Catherine H Taylor; Ashley K McCusker; Gary C Davis; Hali A Hartmann; H White; Milton L Brown; Manoj K Patel
A pharmacophore derived phenytoin analogue with increased affinity for slow inactivated sodium channels exhibits a desired anticonvulsant profile.
Neuropharmacology 2007;52(3):1044-54.
2007: Paulianda J Jones; Yuesheng Wang; Misty Smith; Nicholas J Hargus; Hilary S Eidam; H White; Jaideep Kapur; Milton L Brown; Manoj K Patel
Hydroxyamide analogs of propofol exhibit state-dependent block of sodium channels in hippocampal neurons: implications for anticonvulsant activity.
The Journal of pharmacology and experimental therapeutics 2007;320(2):828-36.
2007: H White; Misty Smith; Karen S Wilcox
Mechanisms of action of antiepileptic drugs.
International review of neurobiology 2007;81():85-110.
2007: Misty Smith; Karen S Wilcox; H White
Discovery of antiepileptic drugs.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2007;4(1):12-7.
2007: Eyal Sobol; Boris Yagen; John G Lamb; H White; Bogdan Wlodarczyk; Richard Finnell; Meir Bialer
Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.
Epilepsy research 2007;73(1):75-84.
2006: Timothy A Simeone; James Otto; Karen S Wilcox; H White
Felbamate is a subunit selective modulator of recombinant gamma-aminobutyric acid type A receptors expressed in Xenopus oocytes.
European journal of pharmacology 2006;552(1-3):31-5.
2006: Sara Eyal; John G Lamb; Misty Smith; Boris Yagen; E Fibach; Yoram Altschuler; H White; Meir Bialer
The antiepileptic and anticancer agent, valproic acid, induces P-glycoprotein in human tumour cell lines and in rat liver.
British journal of pharmacology 2006;149(3):250-60.
2006: Timothy A Simeone; Karen S Wilcox; H White
Subunit selectivity of topiramate modulation of heteromeric GABA(A) receptors.
Neuropharmacology 2006;50(7):845-57.
2006: C F Poulsen; I Schousboe; Alan Sarup; H White; Arne Schousboe
Effect of topiramate and dBcAMP on expression of the glutamate transporters GLAST and GLT-1 in astrocytes cultured separately, or together with neurons.
Neurochemistry international 2006;48(6-7):657-61.
2006: Rasmus P Clausen; Bente Frølund; Orla M Larsson; Arne Schousboe; Povl Krogsgaard-Larsen; H White
A novel selective gamma-aminobutyric acid transport inhibitor demonstrates a functional role for GABA transporter subtype GAT2/BGT-1 in the CNS.
Neurochemistry international 2006;48(6-7):637-42.
2006: James Otto; Yan Yang; Wayne N Frankel; H White; Karen S Wilcox
A spontaneous mutation involving Kcnq2 (Kv7.2) reduces M-current density and spike frequency adaptation in mouse CA1 neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(7):2053-9.
2006: Ilo E Leppik; Kevin M Kelly; Leyla deToledo-Morrell; Peter R Patrylo; Robert J DeLorenzo; Gary W Mathern; H White
Basic research in epilepsy and aging.
Epilepsy research 2006;68 Suppl 1():S21-37.
2005: H White
Molecular pharmacology of topiramate: managing seizures and preventing migraine.
Headache 2005;45 Suppl 1():S48-56.
2005: H White; William P Watson; Suzanne L Hansen; Scott Slough; Jens Perregaard; Alan Sarup; Tina Bolvig; Gitte Petersen; Orla M Larsson; Rasmus P Clausen; Bente Frølund; Erik Falch; Povl Krogsgaard-Larsen; Arne Schousboe
First demonstration of a functional role for central nervous system betaine/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors of mGAT1 and mGAT2.
The Journal of pharmacology and experimental therapeutics 2005;312(2):866-74.
2005: Brian D Klein; Ying-Hui Fu; Louis J Ptacek; H White
Auditory deficits associated with the frings mgr1 (mass1) mutation in mice.
Developmental neuroscience 2005;27(5):321-32.
2004: Meir Bialer; Roy E Twyman; H White
Correlation analysis between anticonvulsant ED50 values of antiepileptic drugs in mice and rats and their therapeutic doses and plasma levels.
Epilepsy & behavior : E&B 2004;5(6):866-72.
2004: Richard T Layer; John D Wagstaff; H White
Conantokins: peptide antagonists of NMDA receptors.
Current medicinal chemistry 2004;11(23):3073-84.
2004: Brian D Klein; Ying-Hui Fu; Louis J Ptacek; H White
c-Fos immunohistochemical mapping of the audiogenic seizure network and tonotopic neuronal hyperexcitability in the inferior colliculus of the Frings mouse.
Epilepsy research 2004;62(1):13-25.
2004: Arne Schousboe; Alan Sarup; Orla M Larsson; H White
GABA transporters as drug targets for modulation of GABAergic activity.
Biochemical pharmacology 2004;68(8):1557-63.
2004: Arne Schousboe; Orla M Larsson; Alan Sarup; H White
Role of the betaine/GABA transporter (BGT-1/GAT2) for the control of epilepsy.
European journal of pharmacology 2004;500(1-3):281-7.
2004: James Otto; Yan Yang; Wayne N Frankel; Karen S Wilcox; H White
Mice carrying the szt1 mutation exhibit increased seizure susceptibility and altered sensitivity to compounds acting at the m-channel.
Epilepsia 2004;45(9):1009-16.
2004: Rachel Hoover; Melissa Motta; Jason Davis; Kathryn E Saatman; Scott T Fujimoto; Hilaire J Thompson; John F Stover; Marc A Dichter; Roy Twyman; H White; Tracy K McIntosh
Differential effects of the anticonvulsant topiramate on neurobehavioral and histological outcomes following traumatic brain injury in rats.
Journal of neurotrauma 2004;21(5):501-12.
2004: Matthew E Barton; H White; Karen S Wilcox
The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on NMDA receptor-mediated EPSCs.
Epilepsy research 2004;59(1):13-24.
2004: Matthew E Barton; H White
The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on kindling acquisition and expression.
Epilepsy research 2004;59(1):1-12.
2004: Nina Isoherranen; René H Levy; Boris Yagen; José H Woodhead; H White; Meir Bialer
Metabolism of a new antiepileptic drug, N-methyl-tetramethylcyclopropanecarboxamide, and anticonvulsant activity of its metabolites.
Epilepsy research 2004;58(1):1-12.
2004: Claus F Poulsen; Timothy A Simeone; Thomas E Maar; Virginia L Smith-Swintosky; H White; Arne Schousboe
Modulation by topiramate of AMPA and kainate mediated calcium influx in cultured cerebral cortical, hippocampal and cerebellar neurons.
Neurochemical research 2004;29(1):275-82.
2003: James P Stables; Ed Bertram; F E Dudek; Greg Holmes; Gary W Mathern; Asla Pitkanen; H White
Therapy discovery for pharmacoresistant epilepsy and for disease-modifying therapeutics: summary of the NIH/NINDS/AES models II workshop.
Epilepsia 2003;44(12):1472-8.
2003: Sean D Donevan; H White; Gail D Anderson; Jong M Rho
Voltage-dependent block of N-methyl-D-aspartate receptors by the novel anticonvulsant dibenzylamine, a bioactive constituent of L-(+)-beta-hydroxybutyrate.
Epilepsia 2003;44(10):1274-9.
2003: Nina Isoherranen; H White; Brian D Klein; Michael Roeder; José H Woodhead; Volker Schurig; Boris Yagen; Meir Bialer
Pharmacokinetic-pharmacodynamic relationships of (2S,3S)-valnoctamide and its stereoisomer (2R,3S)-valnoctamide in rodent models of epilepsy.
Pharmaceutical research 2003;20(8):1293-301.
2003: Nina Isoherranen; Boris Yagen; Ofer Spiegelstein; Richard Finnell; Michelle Merriweather; José H Woodhead; Bogdan Wlodarczyk; H White; Meir Bialer
Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice.
British journal of pharmacology 2003;139(4):755-64.
2003: Yan Yang; Barbara Beyer; James Otto; Timothy P O'Brien; Verity A Letts; H White; Wayne N Frankel
Spontaneous deletion of epilepsy gene orthologs in a mutant mouse with a low electroconvulsive threshold.
Human molecular genetics 2003;12(9):975-84.
2003: Nina Isoherranen; Boris Yagen; José H Woodhead; Ofer Spiegelstein; Simcha Blotnik; Karen S Wilcox; Richard Finnell; Gregory D Bennett; H White; Meir Bialer
Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents.
British journal of pharmacology 2003;138(4):602-13.
2003: H White
Preclinical development of antiepileptic drugs: past, present, and future directions.
Epilepsia 2003;44 Suppl 7():2-8.
2003: H White
Mechanism of action of newer anticonvulsants.
The Journal of clinical psychiatry 2003;64 Suppl 8():5-8.
2002: H White
Animal models of epileptogenesis.
Neurology 2002;59(9 Suppl 5):S7-S14.
2002: James P Stables; Edward H Bertram; H White; Douglas A Coulter; Marc A Dichter; Margaret P Jacobs; Wolfgang Loscher; Daniel H Lowenstein; Solomon L Moshe; Jeffrey L Noebels; Mirian Davis
Models for epilepsy and epileptogenesis: report from the NIH workshop, Bethesda, Maryland.
Epilepsia 2002;43(11):1410-20.
2002: Elsie C Jimenez; Sean D Donevan; Craig Walker; Li-Ming Zhou; Jake Nielsen; Lourdes J Cruz; Heather Armstrong; H White; Baldomero M Olivera
Conantokin-L, a new NMDA receptor antagonist: determinants for anticonvulsant potency.
Epilepsy research 2002;51(1-2):73-80.
2002: H White; Alan Sarup; Tina Bolvig; Anders Skov Kristensen; Gitte Petersen; Nathan Nelson; Darryl S Pickering; Orla M Larsson; Bente Frølund; Povl Krogsgaard-Larsen; Arne Schousboe
Correlation between anticonvulsant activity and inhibitory action on glial gamma-aminobutyric acid uptake of the highly selective mouse gamma-aminobutyric acid transporter 1 inhibitor 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole and its N-alkylated analogs.
The Journal of pharmacology and experimental therapeutics 2002;302(2):636-44.
2002: Jong M Rho; Gail D Anderson; Sean D Donevan; H White
Acetoacetate, acetone, and dibenzylamine (a contaminant in l-(+)-beta-hydroxybutyrate) exhibit direct anticonvulsant actions in vivo.
Epilepsia 2002;43(4):358-61.
2002: Nina Isoherranen; H White; Richard Finnell; Boris Yagen; José H Woodhead; Gregory D Bennett; Karen S Wilcox; Matthew E Barton; Meir Bialer
Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug.
Epilepsia 2002;43(2):115-26.
2001: Matthew E Barton; Brian D Klein; HH Wolf; H White
Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy.
Epilepsy research 2001;47(3):217-27.
2001: SL Skradski; A M Clark; H Jiang; H White; Ying-Hui Fu; Louis J Ptácek
A novel gene causing a mendelian audiogenic mouse epilepsy.
Neuron 2001;31(4):537-44.
2001: Nina Isoherranen; José H Woodhead; H White; Meir Bialer
Anticonvulsant profile of valrocemide (TV1901): a new antiepileptic drug.
Epilepsia 2001;42(7):831-6.
2001: Wayne N Frankel; L Taylor; Barbara Beyer; Bruce Tempel; H White
Electroconvulsive thresholds of inbred mouse strains.
Genomics 2001;74(3):306-12.
2000: H Lian; S S Steiner; R D Sofia; JH Woodhead; HH Wolf; H White; G S Shen; C A Rhodes; RT McCabe
A self-complementary, self-assembling microsphere system: application for intravenous delivery of the antiepileptic and neuroprotectant compound felbamate.
Journal of pharmaceutical sciences 2000;89(7):867-75.
2000: Brian D Klein; H White; Karleen S Callahan
Cytokine and intracellular signaling regulation of tissue factor expression in astrocytes.
Neurochemistry international 2000;36(4-5):441-9.
2000: SL Skradski; H White
Topiramate blocks kainate-evoked cobalt influx into cultured neurons.
Epilepsia 2000;41 Suppl 1():S45-7.
2000: H White; S D Brown; JH Woodhead; GA Skeen; HH Wolf
Topiramate modulates GABA-evoked currents in murine cortical neurons by a nonbenzodiazepine mechanism.
Epilepsia 2000;41 Suppl 1():S17-20.
2000: H White; RT McCabe; H Armstrong; Sean D Donevan; Lourdes J Cruz; Fe C Abogadie; Josep Torres; Jean E Rivier; I Paarmann; Michael Hollmann; Baldomero M Olivera
In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus.
The Journal of pharmacology and experimental therapeutics 2000;292(1):425-32.
1999: Erik Falch; Jens Perregaard; B FrŁlund; B SŁkilde; Anders Buur; L M Hansen; Karla Frydenvang; Lotte Brehm; Tina Bolvig; Orla M Larsson; Connie Sanchez; H White; Arne Schousboe; Povl Krogsgaard-Larsen
Selective inhibitors of glial GABA uptake: synthesis, absolute stereochemistry, and pharmacology of the enantiomers of 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole (exo-THPO) and analogues.
Journal of medicinal chemistry 1999;42(26):5402-14.
1999: Glen R Hanson; M Jensen; M Johnson; H White
Distinct features of seizures induced by cocaine and amphetamine analogs.
European journal of pharmacology 1999;377(2-3):167-73.
1999: Patricia Salvati; Roberto Maj; Carla Caccia; MA Cervini; MG Fornaretto; E Lamberti; Paolo Pevarello; GA Skeen; H White; HH Wolf; Laura Faravelli; Michele Mazzanti; Enzo Mancinelli; Mario Varasi; Ruggero G Fariello
Biochemical and electrophysiological studies on the mechanism of action of PNU-151774E, a novel antiepileptic compound.
The Journal of pharmacology and experimental therapeutics 1999;288(3):1151-9.
1999: H White
Comparative anticonvulsant and mechanistic profile of the established and newer antiepileptic drugs.
Epilepsia 1999;40 Suppl 5():S2-10.
1998: Scott W Rogers; Lorise C Gahring; H White
Glutamate receptor GluR1 expression is altered selectively by chronic audiogenic seizures in the Frings mouse brain.
Journal of neurobiology 1998;35(2):209-16.
1998: Ruggero G Fariello; Robert McArthur; A Bonsignori; MA Cervini; Roberto Maj; P Marrari; Paolo Pevarello; HH Wolf; J W Woodhead; H White; Mario Varasi; Patricia Salvati; C Post
Preclinical evaluation of PNU-151774E as a novel anticonvulsant.
The Journal of pharmacology and experimental therapeutics 1998;285(2):397-403.
1998: SL Skradski; H White; Louis J Ptácek
Genetic mapping of a locus (mass1) causing audiogenic seizures in mice.
Genomics 1998;49(2):188-92.
1998: H White; HH Wolf; JH Woodhead; Harvey J Kupferberg
The National Institutes of Health Anticonvulsant Drug Development Program: screening for efficacy.
Advances in neurology 1998;76():29-39.
1997: H White; S D Brown; JH Woodhead; GA Skeen; HH Wolf
Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold.
Epilepsy research 1997;28(3):167-79.
1997: A S Bender; D M Woodbury; H White
The rapid L- and D-aspartate uptake in cultured astrocytes.
Neurochemical research 1997;22(6):721-6.
1997: Lorise C Gahring; H White; SL Skradski; Noel G Carlson; Scott W Rogers
Interleukin-1alpha in the brain is induced by audiogenic seizure.
Neurobiology of disease 1997;3(4):263-9.
1997: H White
Clinical significance of animal seizure models and mechanism of action studies of potential antiepileptic drugs.
Epilepsia 1997;38 Suppl 1():S9-17.
1996: A Rostock; C Tober; Chris Rundfeldt; R Bartsch; J Engel; E E Polymeropoulos; B Kutscher; W Löscher; D Hönack; H White; HH Wolf
D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures.
Epilepsy research 1996;23(3):211-23.
1995: GC Palmer; M L Stagnitto; G E Garske; J J Napier; E W Harris; F C Kaiser; R C Griffith; JH Woodhead; H White; HH Wolf
Anticonvulsant efficacy/safety properties of 2-amino-N-(1,2-diphenylethyl)acetamide hydrochloride.
The Journal of pharmacology and experimental therapeutics 1995;273(3):1023-31.
1995: H White; M Johnson; HH Wolf; H J Kupferberg
The early identification of anticonvulsant activity: role of the maximal electroshock and subcutaneous pentylenetetrazol seizure models.
Italian journal of neurological sciences 1995;16(1-2):73-7.
1995: H White; W L Harmsworth; R D Sofia; HH Wolf
Felbamate modulates the strychnine-insensitive glycine receptor.
Epilepsy research 1995;20(1):41-8.
1994: Francis M Filloux; R C Fitts; G A Skeen; H White
The dihydropyridine nitrendipine inhibits [3H]MK 801 binding to mouse brain sections.
European journal of pharmacology 1994;269(3):325-30.
1994: A S Bender; D M Woodbury; H White
Ionic dependence of adenosine uptake into cultured astrocytes.
Brain research 1994;661(1-2):1-8.
1994: G A Skeen; H White; Roy E Twyman
The dihydropyridine nitrendipine reduces N-methyl-D-aspartate (NMDA)-evoked currents of rodent cortical neurons through a direct interaction with the NMDA receptor-associated ion channel.
The Journal of pharmacology and experimental therapeutics 1994;271(1):30-8.
1993: G A Skeen; Roy E Twyman; H White
The dihydropyridine nitrendipine modulates N-methyl-D-aspartate receptor channel function in mammalian neurons.
Molecular pharmacology 1993;44(2):443-50.
1993: H White; J Hunt; HH Wolf; E A Swinyard; Erik Falch; P Krogsgaard-Larsen; A Schousboe
Anticonvulsant activity of the gamma-aminobutyric acid uptake inhibitor N-4,4-diphenyl-3-butenyl-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol .
European journal of pharmacology 1993;236(1):147-9.
1993: E A Swinyard; HH Wolf; H White; G A Skeen; L G Stark; Timothy E Albertson; S F Pong; E G Drust
Characterization of the anticonvulsant properties of F-721.
Epilepsy research 1993;15(1):35-45.
1992: H White; S Patel; B S Meldrum
Anticonvulsant profile of MDL 27,266: an orally active, broad-spectrum anticonvulsant agent.
Epilepsy research 1992;12(3):217-26.
1992: B M Baron; B L Harrison; Ian McDonald; B S Meldrum; M G Palfreyman; F G Salituro; B W Siegel; A L Slone; J P Turner; H White
Potent indole- and quinoline-containing N-methyl-D-aspartate antagonists acting at the strychnine-insensitive glycine binding site.
The Journal of pharmacology and experimental therapeutics 1992;262(3):947-56.
1992: F G Salituro; B L Harrison; B M Baron; P L Nyce; K T Stewart; John H Kehne; H White; Ian McDonald
3-(2-Carboxyindol-3-yl)propionic acid-based antagonists of the N-methyl-D-aspartic acid receptor associated glycine binding site.
Journal of medicinal chemistry 1992;35(10):1791-9.
1992: H White; HH Wolf; E A Swinyard; G A Skeen; R D Sofia
A neuropharmacological evaluation of felbamate as a novel anticonvulsant.
Epilepsia 1992;33(3):564-72.
1992: H White; G A Skeen; James Allen Edwards
Pharmacological regulation of astrocytic calcium channels: implications for the treatment of seizure disorders.
Progress in brain research 1992;94():77-87.
1992: H White; S Y Chow; Y C Yen-Chow; D M Woodbury
Effect of elevated potassium on the ion content of mouse astrocytes and neurons.
Canadian journal of physiology and pharmacology 1992;70 Suppl():S263-8.
1991: S Y Chow; Y C Yen-Chow; H White; L Hertz; D M Woodbury
Effects of potassium on the anion and cation contents of primary cultures of mouse astrocytes and neurons.
Neurochemical research 1991;16(12):1275-83.
1991: E A Swinyard; H White; HH Wolf; W E Bondinell
Anticonvulsant profiles of the potent and orally active GABA uptake inhibitors SK&F 89976-A and SK&F 100330-A and four prototype antiepileptic drugs in mice and rats.
Epilepsia 1991;32(4):569-77.
1991: S Y Chow; Y C Yen-Chow; H White; D M Woodbury
pH regulation after acid load in primary cultures of mouse astrocytes.
Brain research. Developmental brain research 1991;60(1):69-78.
1991: GC Palmer; M L Stagnitto; J M Ordy; R C Griffith; J J Napier; R J Gentile; JH Woodhead; H White; E A Swinyard
Preclinical profile of stereoisomers of the anticonvulsant remacemide in mice.
Epilepsy research 1991;8(1):36-48.
1991: D N Johnson; H White; E A Swinyard; Timothy E Albertson; B F Kilpatrick
AHR-12245: a potential anti-absence drug.
Epilepsy research 1991;8(1):64-70.
1990: J P Whitten; B M Baron; D Muench; F Miller; H White; Ian McDonald
(R)-4-oxo-5-phosphononorvaline: a new competitive glutamate antagonist at the NMDA receptor complex.
Journal of medicinal chemistry 1990;33(11):2961-3.
1990: B M Baron; B L Harrison; F P Miller; Ian McDonald; F G Salituro; CJ Schmidt; S M Sorensen; H White; M G Palfreyman
Activity of 5,7-dichlorokynurenic acid, a potent antagonist at the N-methyl-D-aspartate receptor-associated glycine binding site.
Molecular pharmacology 1990;38(4):554-61.
1989: S Y Chow; H White; Y C Yen-Chow; D M Woodbury
Uptakes of iodide and chloride by primary cultures of mouse astrocytes and neurons.
Neurochemical research 1989;14(10):963-9.
1989: A S Bender; D M Woodbury; H White
Beta-DL-methylene-aspartate, an inhibitor of aspartate aminotransferase, potently inhibits L-glutamate uptake into astrocytes.
Neurochemical research 1989;14(7):641-6.
1989: Leif Hertz; A S Bender; D M Woodbury; H White
Potassium-stimulated calcium uptake in astrocytes and its potent inhibition by nimodipine.
Journal of neuroscience research 1989;22(2):209-15.
1988: H White; A S Bender; E A Swinyard
Effect of the selective N-methyl-D-aspartate receptor agonist 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid on [3H]flunitrazepam binding.
European journal of pharmacology 1988;147(1):149-51.
1987: S Y Chow; Y C Yen-Chow; H White; D M Woodbury
Effects of 4,4'-di-isothiocyano-2,2'-stilbene disulphonate on iodide uptake by primary cultures of turtle thyroid follicular cells.
The Journal of endocrinology 1987;113(3):403-12.
1986: S Y Chow; Y C Yen-Chow; H White; D M Woodbury
Effects of sodium on iodide transport in primary cultures of turtle thyroid cells.
The American journal of physiology 1986;250(4 Pt 1):E464-9.
1986: H White; D M Woodbury; C F Chen; J W Kemp; S Y Chow; Y C Yen-Chow
Role of glial cation and anion transport mechanisms in etiology and arrest of seizures.
Advances in neurology 1986;44():695-712.
1986: F L Engstrom; H White; J W Kemp; D M Woodbury
Acute and chronic acetazolamide administration in DBA and C57 mice: effects of age.
Epilepsia 1986;27(1):19-26.
1985: H White; Y C Yen-Chow; S Y Chow; J W Kemp; D M Woodbury
Effects of phenytoin on primary glial cell cultures.
Epilepsia 1985;26(1):58-68.
1985: H White; C F Chen; J W Kemp; D M Woodbury
Effects of acute and chronic phenytoin on the electrolyte content and the activities of Na+, K+-, Ca2+, Mg2+-, and HCO3- -ATPases and carbonic anhydrase of neonatal and adult rat cerebral cortex.
Epilepsia 1985;26(1):43-57.
1984: D M Woodbury; F L Engstrom; H White; C F Chen; J W Kemp; S Y Chow
Ionic and acid-base regulation of neurons and glia during seizures.
Annals of neurology 1984;16 Suppl():S135-44.