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Andrew Darnel

Research Profile

Procedures

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Publications

TOP 3
Matei Mireuta; Andrew Darnel; Michael Pollak
IGFBP-2 expression in MCF-7 cells is regulated by the PI3K/AKT/mTOR pathway through Sp1-induced increase in transcription.
Anas Alazzam; Etienne Mfoumou; Ion Stiharu; Amal Kassab; Andrew Darnel; Amber Yasmeen; Narayanswamy Sivakumar; Rama Bhat; Ala-Eddin Al Moustafa
Identification of deregulated genes by single wall carbon-nanotubes in human normal bronchial epithelial cells.
Andrew Darnel; Emy Behmoaram; Robin T Vollmer; Jacques Corcos; Krikor Bijian; Kanishka Sircar; Jie Su; Jinsong Jiao; Moulay A Alaoui-Jamali; Tarek A Bismar
Fascin regulates prostate cancer cell invasion and is associated with metastasis and biochemical failure in prostate cancer.

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All Publications

2010: Matei Mireuta; Andrew Darnel; Michael Pollak
IGFBP-2 expression in MCF-7 cells is regulated by the PI3K/AKT/mTOR pathway through Sp1-induced increase in transcription.
Growth factors (Chur, Switzerland) 2010;28(4):243-55.
2010: Anas Alazzam; Etienne Mfoumou; Ion Stiharu; Amal Kassab; Andrew Darnel; Amber Yasmeen; Narayanswamy Sivakumar; Rama Bhat; Ala-Eddin Al Moustafa
Identification of deregulated genes by single wall carbon-nanotubes in human normal bronchial epithelial cells.
Nanomedicine : nanotechnology, biology, and medicine 2010;6(4):563-9.
2009: Andrew Darnel; Emy Behmoaram; Robin T Vollmer; Jacques Corcos; Krikor Bijian; Kanishka Sircar; Jie Su; Jinsong Jiao; Moulay A Alaoui-Jamali; Tarek A Bismar
Fascin regulates prostate cancer cell invasion and is associated with metastasis and biochemical failure in prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(4):1376-83.
2008: Emy Behmoaram; Krikor Bijian; Su Jie; Yingjie Xu; Andrew Darnel; Tarek A Bismar; Moulay A Alaoui-Jamali
Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness.
The American journal of pathology 2008;173(5):1540-50.
2008: N Akil; A Yasmeen; A Kassab; L Ghabreau; Andrew Darnel; A-E Al Moustafa
High-risk human papillomavirus infections in breast cancer in Syrian women and their association with Id-1 expression: a tissue microarray study.
British journal of cancer 2008;99(3):404-7.
2008: N Akil; A Kassab; Amber Yasmeen; Andrew Darnel; Tarek A Bismar; Ala-Eddin Al Moustafa
Human breast cancer and sexual activities.
British journal of cancer 2008;98(2):508-9; author reply 510-11.
2008: Ala-Eddin Al Moustafa; Amal Kassab; Andrew Darnel; Amber Yasmeen
High-risk HPV/ErbB-2 interaction on E-cadherin/catenin regulation in human carcinogenesis.
Current pharmaceutical design 2008;14(22):2159-72.
2007: William D Foulkes; Parviz Ghadirian; Mohammed Reza Akbari; Nancy Hamel; Sylvie Giroux; Nelly Sabbaghian; Andrew Darnel; Robert Royer; Aletta Poll; Eve Fafard; André Robidoux; Ginette Martin; Tarek A Bismar; Marc Tischkowitz; Francois Rousseau; Steven A Narod
Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women.
Breast cancer research : BCR 2007;9(6):R83.
2004: Masato Ishizuka; Masahito Hatori; Takashi Suzuki; Yasuhiro Miki; Andrew Darnel; Chika Tazawa; Takashi Sawai; Miwa Uzuki; Yasuhisa Tanaka; Shoichi Kokubun; Hironobu Sasano
Sex steroid receptors in rheumatoid arthritis.
Clinical science (London, England : 1979) 2004;106(3):293-300.
2003: Yuichiro Kimura; Takashi Suzuki; Chika Kaneko; Andrew Darnel; Jun-ichi Akahira; Masahito Ebina; Toshihiro Nukiwa; Hironobu Sasano
Expression of androgen receptor and 5alpha-reductase types 1 and 2 in early gestation fetal lung: a possible correlation with branching morphogenesis.
Clinical science (London, England : 1979) 2003;105(6):709-13.
2003: Yasuhiro Nakamura; Yasuhiro Miki; Takashi Suzuki; Taisuke Nakata; Andrew Darnel; Takuya Moriya; Chika Tazawa; Haruo Saito; Tadashi Ishibashi; Shoki Takahashi; Shogo Yamada; Hironobu Sasano
Steroid sulfatase and estrogen sulfotransferase in the atherosclerotic human aorta.
The American journal of pathology 2003;163(4):1329-39.
2003: Satoshi Suzuki; Hiroyoshi Tsubochi; Andrew Darnel; Takashi Suzuki; Hironobu Sasano; Zygmunt Krozowski; Takashi Kondo
Expression of 11 beta-hydroxysteroid dehydrogenase type 1 in alveolar epithelial cells in rats.
Endocrine journal 2003;50(4):445-51.
2003: Masao Nakabayashi; Takashi Suzuki; Kazuhiro Takahashi; Kazuhito Totsune; Yasunari Muramatsu; Chika Kaneko; Fumiko Date; Junji Takeyama; Andrew Darnel; Takuya Moriya; Hironobu Sasano
Orexin-A expression in human peripheral tissues.
Molecular and cellular endocrinology 2003;205(1-2):43-50.
2003: Akinobu Konishi; Chika Tazawa; Yasuhiro Miki; Andrew Darnel; Takashi Suzuki; Yoshio Ohta; Tsuneyuki Suzuki; Koichi Tabayashi; Hironobu Sasano
The possible roles of mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type 2 in cardiac fibrosis in the spontaneously hypertensive rat.
The Journal of steroid biochemistry and molecular biology 2003;85(2-5):439-42.
2003: Satoshi Suzuki; Kaori Koyama; Andrew Darnel; Hironori Ishibashi; Seiichi Kobayashi; Hiroshi Kubo; Takashi Suzuki; Hironobu Sasano; Zygmunt Krozowski
Dexamethasone upregulates 11beta-hydroxysteroid dehydrogenase type 2 in BEAS-2B cells.
American journal of respiratory and critical care medicine 2003;167(9):1244-9.
2002: Yasuhiro Miki; Taisuke Nakata; Takashi Suzuki; Andrew Darnel; Takuya Moriya; Chika Kaneko; Kumiko Hidaka; Yukimasa Shiotsu; Hideaki Kusaka; Hironobu Sasano
Systemic distribution of steroid sulfatase and estrogen sulfotransferase in human adult and fetal tissues.
The Journal of clinical endocrinology and metabolism 2002;87(12):5760-8.
2002: Yuichiro Kimura; Takashi Suzuki; Chika Kaneko; Andrew Darnel; Takuya Moriya; Satoshi Suzuki; Masashi Handa; Masahito Ebina; Toshihiro Nukiwa; Hironobu Sasano
Retinoid receptors in the developing human lung.
Clinical science (London, England : 1979) 2002;103(6):613-21.
2002: Tsukasa Inoue; Jun-ichi Akahira; Takashi Suzuki; Andrew Darnel; Chika Kaneko; Kazuhiro Takahashi; Masahito Hatori; Reizo Shirane; Toshihiro Kumabe; Yoshimochi Kurokawa; Susumu Satomi; Hironobu Sasano
Progesterone production and actions in the human central nervous system and neurogenic tumors.
The Journal of clinical endocrinology and metabolism 2002;87(11):5325-31.
2002: Takashi Suzuki; Barbara A Murry; Andrew Darnel; Hironobu Sasano
Progesterone metabolism in human leukemic monoblast U937 cells.
Endocrine journal 2002;49(5):539-46.
2002: Jun-ichi Akahira; Takashi Suzuki; Kiyoshi Ito; Chika Kaneko; Andrew Darnel; Takuya Moriya; Kunihiro Okamura; Nobuo Yaegashi; Hironobu Sasano
Differential expression of progesterone receptor isoforms A and B in the normal ovary, and in benign, borderline, and malignant ovarian tumors.
Japanese journal of cancer research : Gann 2002;93(7):807-15.
2002: Yuichiro Kimura; Kazuhiro Takahashi; Kazuhito Totsune; Yasunari Muramatsu; Chika Kaneko; Andrew Darnel; Takashi Suzuki; Masahito Ebina; Toshihiro Nukiwa; Hironobu Sasano
Expression of urocortin and corticotropin-releasing factor receptor subtypes in the human heart.
The Journal of clinical endocrinology and metabolism 2002;87(1):340-6.
2001: T Sano; G Hirasawa; Junji Takeyama; Andrew Darnel; Takashi Suzuki; Takuya Moriya; K Kato; Hitoshi Sekine; Shuichi Ohara; Tooru Shimosegawa; J Nakamura; M Yoshihama; N Harada; Hironobu Sasano
17 beta-Hydroxysteroid dehydrogenase type 2 expression and enzyme activity in the human gastrointestinal tract.
Clinical science (London, England : 1979) 2001;101(5):485-91.
2001: Jun-ichi Akahira; Takashi Suzuki; Kiyoshi Ito; Andrew Darnel; Takuya Moriya; S Sato; Nobuo Yaegashi; K Okamura; Hironobu Sasano
Expression of 5alpha-reductases in human epithelial ovarian cancer: its correlation with androgen receptor status.
Japanese journal of cancer research : Gann 2001;92(9):926-32.
2001: T Inoue; Jun-ichi Akahira; Junji Takeyama; Takashi Suzuki; Andrew Darnel; Chika Kaneko; Yoshimochi Kurokawa; S Satomi; Hironobu Sasano
Spatial and topological distribution of progesterone receptor A and B isoforms during human development.
Molecular and cellular endocrinology 2001;182(1):83-9.
2001: Takashi Suzuki; Andrew Darnel; Jun-ichi Akahira; N Ariga; S Ogawa; Chika Kaneko; Junji Takeyama; Takuya Moriya; Hironobu Sasano
5alpha-reductases in human breast carcinoma: possible modulator of in situ androgenic actions.
The Journal of clinical endocrinology and metabolism 2001;86(5):2250-7.
2001: Satoshi Suzuki; Hiroyoshi Tsubochi; Takashi Suzuki; Andrew Darnel; Zygmunt Krozowski; Hironobu Sasano; Takashi Kondo
Modulation of transalveolar fluid absorption by endogenous aldosterone in adult rats.
Experimental lung research 2001;27(2):143-55.
2001: Takashi Suzuki; Hironobu Sasano; Chika Kaneko; S Ogawa; Andrew Darnel; Zygmunt Krozowski
Immunohistochemical distribution of 11beta-hydroxysteroid dehydrogenase in human eye.
Molecular and cellular endocrinology 2001;173(1-2):121-5.
2000: Takashi Suzuki; Kazuhiro Takahashi; Andrew Darnel; O Murakami; Toshiaki Narasaka; Junji Takeyama; Hironobu Sasano
Chicken ovalbumin upstream promoter transcription factor II in the human adrenal cortex and its disorders.
The Journal of clinical endocrinology and metabolism 2000;85(8):2752-7.
2000: Takashi Suzuki; Takuya Moriya; Andrew Darnel; Junji Takeyama; Hironobu Sasano
Immunohistochemical distribution of chicken ovalbumin upstream promoter transcription factor II in human tissues.
Molecular and cellular endocrinology 2000;164(1-2):69-75.
2000: G Hirasawa; Junji Takeyama; Hironobu Sasano; K Fukushima; Takashi Suzuki; Y Muramatu; Andrew Darnel; Chika Kaneko; N Hiwatashi; T Toyota; Hiroshi Nagura; Zygmunt Krozowski
11Beta-hydroxysteroid dehydrogenase type II and mineralocorticoid receptor in human placenta.
The Journal of clinical endocrinology and metabolism 2000;85(3):1306-9.
1999: Andrew Darnel; Trevor K Archer; Kaiping Yang
Regulation of 11beta-hydroxysteroid dehydrogenase type 2 by steroid hormones and epidermal growth factor in the Ishikawa human endometrial cell line.
The Journal of steroid biochemistry and molecular biology 1999;70(4-6):203-10.
1997: H Asano; K Shearman; Andrew Darnel; Bryan S Richardson; Kaiping Yang
Effects of sustained hypoxaemia with 72 hours recovery on 11beta-hydroxysteroid dehydrogenase types 1 and 2 gene expression in near-term fetal sheep.
Reproduction, fertility, and development 1997;9(8):755-61.
1996: Kaiping Yang; M Fraser; M Yu; M Krkosek; John R G Challis; G E Lamming; L E Campbell; Andrew Darnel
Pattern of 11 beta-hydroxysteroid dehydrogenase type 1 messenger ribonucleic acid expression in the ovine uterus during the estrous cycle and pregnancy.
Biology of reproduction 1996;55(6):1231-6.