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Michael Mühlebach

Research Profile

Living Beings

Physiology

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Virus Internalization

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Publications

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Katrin Friedrich; Jan Rh Hanauer; Kay-Martin Hanschmann; Christian Jost; Christian J Buchholz; Roberto Cattaneo; Klaus Cichutek; Christodoulos Filippis; Robert C Münch; Kah-Whye Peng; Andreas Plückthun; Steffen Prüfer; Iris Völker; Michael Mühlebach
DARPin-targeting of measles virus: unique bispecificity, effective oncolysis, and enhanced safety.
Patricia Bach; Claudia R Ball; Gundula Braun; Tobias Abel; Zoltan Gal; Hanno Glimm; Christel Herold-Mende; Christopher Hoffmann; Ian C D Johnston; Ulrich M Lauer; Michael Mühlebach; Iris Voelker; Christian J Buchholz
Specific elimination of CD133+ tumor cells with targeted oncolytic measles virus.
Michael Mühlebach; Steffen Prüfer; Marc Lopez; Xiao X Wong; Paul B McCray; Klaus Cichutek; Mathieu Mateo; Vincent H J Leonard; Patrick L Sinn; Marie Frenzke; Shyam Ramachandran; Katharina M Uhlig; Veronika von Messling; Chanakha K Navaratnarajah; Bevan Sawatsky; Roberto Cattaneo
Adherens junction protein nectin-4 is the epithelial receptor for measles virus.

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All Publications

2013: Katrin Friedrich; Jan Rh Hanauer; Kay-Martin Hanschmann; Christian Jost; Christian J Buchholz; Roberto Cattaneo; Klaus Cichutek; Christodoulos Filippis; Robert C Münch; Kah-Whye Peng; Andreas Plückthun; Steffen Prüfer; Iris Völker; Michael Mühlebach
DARPin-targeting of measles virus: unique bispecificity, effective oncolysis, and enhanced safety.
Molecular therapy : the journal of the American Society of Gene Therapy 2013;21(4):849-59.
2013: Patricia Bach; Claudia R Ball; Gundula Braun; Tobias Abel; Zoltan Gal; Hanno Glimm; Christel Herold-Mende; Christopher Hoffmann; Ian C D Johnston; Ulrich M Lauer; Michael Mühlebach; Iris Voelker; Christian J Buchholz
Specific elimination of CD133+ tumor cells with targeted oncolytic measles virus.
Cancer research 2013;73(2):865-74.
2011: Michael Mühlebach; Steffen Prüfer; Marc Lopez; Xiao X Wong; Paul B McCray; Klaus Cichutek; Mathieu Mateo; Vincent H J Leonard; Patrick L Sinn; Marie Frenzke; Shyam Ramachandran; Katharina M Uhlig; Veronika von Messling; Chanakha K Navaratnarajah; Bevan Sawatsky; Roberto Cattaneo
Adherens junction protein nectin-4 is the epithelial receptor for measles virus.
Nature 2011;480(7378):530-3.
2011: Robert C Münch; Michael Mühlebach; Thomas Schaser; Sabrina Kneissl; Christian Jost; Andreas Plückthun; Klaus Cichutek; Christian J Buchholz
DARPins: an efficient targeting domain for lentiviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(4):686-93.
2011: Ulrich Tschulena; Ralf Sanzenbacher; Michael Mühlebach; André Berger; Jan Münch; Michael Schindler; Frank Kirchhoff; Roland Plesker; Cheick Coulibaly; Sylvia Panitz; Steffen Prüfer; Heide Muckenfuss; Matthias Hamdorf; Matthias Schweizer; Klaus Cichutek; Egbert Flory
Mutation of a diacidic motif in SIV-PBj Nef impairs T-cell activation and enteropathic disease.
Retrovirology 2011;8():14.
2010: Michael Mühlebach; Thomas Schaser; Martina Zimmermann; Sorin Armeanu; Kay-Martin O Hanschmann; Roberto Cattaneo; Michael Bitzer; Ulrich M Lauer; Klaus Cichutek; Christian J Buchholz
Liver cancer protease activity profiles support therapeutic options with matrix metalloproteinase-activatable oncolytic measles virus.
Cancer research 2010;70(19):7620-9.
2010: Björn-Philipp Kloke; Silke Schüle; Michael Mühlebach; Nina Wolfrum; Klaus Cichutek; Matthias Schweizer
Functional HIV-2- and SIVsmmPBj- derived lentiviral vectors generated by a novel polymerase chain reaction-based approach.
The journal of gene medicine 2010;12(5):446-52.
2009: Christian J Buchholz; Michael Mühlebach; Klaus Cichutek
Lentiviral vectors with measles virus glycoproteins - dream team for gene transfer?
Trends in biotechnology 2009;27(5):259-65.
2009: S Funke; I C Schneider; S Glaser; Michael Mühlebach; T Moritz; Roberto Cattaneo; Klaus Cichutek; Christian J Buchholz
Pseudotyping lentiviral vectors with the wild-type measles virus glycoproteins improves titer and selectivity.
Gene therapy 2009;16(5):700-5.
2008: Michael Mühlebach; Vincent H J Leonard; Roberto Cattaneo
The measles virus fusion protein transmembrane region modulates availability of an active glycoprotein complex and fusion efficiency.
Journal of virology 2008;82(22):11437-45.
2008: Sabrina Funke; Andrea Maisner; Michael Mühlebach; Ulrike Koehl; Manuel Grez; Roberto Cattaneo; Klaus Cichutek; Christian J Buchholz
Targeted cell entry of lentiviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(8):1427-36.
2007: Nina Wolfrum; Michael Mühlebach; Silke Schüle; Julia K Kaiser; Björn-Philipp Kloke; Klaus Cichutek; Matthias Schweizer
Impact of viral accessory proteins of SIVsmmPBj on early steps of infection of quiescent cells.
Virology 2007;364(2):330-41.
2005: Michael Mühlebach; Nina Wolfrum; Silke Schüle; Ulrich Tschulena; Ralf Sanzenbacher; Egbert Flory; Klaus Cichutek; Matthias Schweizer
Stable transduction of primary human monocytes by simian lentiviral vector PBj.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(6):1206-16.
2004: Stefanie Steidl; Silke Schüle; Michael Mühlebach; Jörn Stitz; Klaus Boller; Klaus Cichutek; Matthias Schweizer
Genetic engineering of onco/lentivirus hybrids results in formation of infectious but not of replication-competent viruses.
The Journal of general virology 2004;85(Pt 3):665-78.
2003: Michael Mühlebach; Isabel Schmitt; Stefanie Steidl; Jörn Stitz; Matthias Schweizer; Thomas Blankenstein; Klaus Cichutek; Wolfgang Uckert
Transduction efficiency of MLV but not of HIV-1 vectors is pseudotype dependent on human primary T lymphocytes.
Journal of molecular medicine (Berlin, Germany) 2003;81(12):801-10.
2001: Jörn Stitz; Michael Mühlebach; Ulrike Blömer; Michaela Scherr; M Selbert; P Wehner; Stefanie Steidl; Isabel Schmitt; Renate König; Matthias Schweizer; Klaus Cichutek
A novel lentivirus vector derived from apathogenic simian immunodeficiency virus.
Virology 2001;291(2):191-7.