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Pang-hsien Tu

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Han-Yun Hsiao; Pang-hsien Tu; Hui-Mei Chen; Yu-Chen Chen; Yijuang Chern
A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease.
Bing-Wen Soong; Pei-Chien Tsai; Pang-hsien Tu; Ming-Hong Chang; Hsin-Ju Chien; Chien-Chang Huang; Yen-Hua Huang; Lung-Sen Kao; Kon-Ping Lin; Tze-Tze Liu; Yi-Chun Lu; Hung-Chuan Pan; Yi-Chung Lee
Exome sequencing identifies GNB4 mutations as a cause of dominant intermediate Charcot-Marie-Tooth disease.
Ching-Paio Tsai; Pei-Chien Tsai; Pang-hsien Tu; Jong-Ling Fuh; I-Hui Lee; Kon-Ping Lin; Yi-Chun Lu; Bing-Wen Soong; Yi-Chung Lee
A hexanucleotide repeat expansion in C9ORF72 causes familial and sporadic ALS in Taiwan.

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2013: Han-Yun Hsiao; Pang-hsien Tu; Hui-Mei Chen; Yu-Chen Chen; Yijuang Chern
A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease.
Human molecular genetics 2013;22(9):1826-42.
2013: Bing-Wen Soong; Pei-Chien Tsai; Pang-hsien Tu; Ming-Hong Chang; Hsin-Ju Chien; Chien-Chang Huang; Yen-Hua Huang; Lung-Sen Kao; Kon-Ping Lin; Tze-Tze Liu; Yi-Chun Lu; Hung-Chuan Pan; Yi-Chung Lee
Exome sequencing identifies GNB4 mutations as a cause of dominant intermediate Charcot-Marie-Tooth disease.
American journal of human genetics 2013;92(3):422-30.
2012: Ching-Paio Tsai; Pei-Chien Tsai; Pang-hsien Tu; Jong-Ling Fuh; I-Hui Lee; Kon-Ping Lin; Yi-Chun Lu; Bing-Wen Soong; Yi-Chung Lee
A hexanucleotide repeat expansion in C9ORF72 causes familial and sporadic ALS in Taiwan.
Neurobiology of aging 2012;33(9):2232.e11-2232.e18.
2012: Min-Shu Hsieh; Long-Wei Lin; Arie Perry; Pang-hsien Tu; Joseph Tien-Min Ho; Abel Po-Hao Huang
Cerebellar anaplastic pilocytic astrocytoma in a patient of neurofibromatosis type-1: case report and review of the literature.
Clinical neurology and neurosurgery 2012;114(7):1027-9.
2012: Pei-Ming Chu; Pei-Chen Hsieh; Bo-Hua Jiang; Yi-Hui Lin; Hsin-I Ma; Yang-Hsin Shih; Tsann-Long Su; Pang-hsien Tu; Li-Hsin Chen; Ming-Teh Chen; Yu-Chih Chen; Chian-Shiu Chien; Shih-Hwa Chiou
Targeting autophagy enhances BO-1051-induced apoptosis in human malignant glioma cells.
Cancer chemotherapy and pharmacology 2012;69(3):621-33.
2012: Wen-Liang Lo; Tsann-Long Su; Ling-Ming Tseng; Pang-hsien Tu; Yi-Wei Chen; Yueh Chien; Pen-Yuan Chu; Pin-I Huang; Shou-Yen Kao; Tsung-Heng Lee; Jeng-Fan Lo
A Combined DNA-Affinic Molecule and N-Mustard Alkylating Agent Has an Anti-Cancer Effect and Induces Autophagy in Oral Cancer Cells.
International journal of molecular sciences 2012;13(3):3277-90.
2012: Li-Hsin Chen; Chin-Wen Chi; Pei-Ming Chu; Hsin-Chen Lee; Yi-Jang Lee; Pang-hsien Tu; Shih-Hwa Chiou
Targeting Protective Autophagy Exacerbates UV-Triggered Apoptotic Cell Death.
International journal of molecular sciences 2012;13(1):1209-24.
2011: Yi-Wei Wang; Jenq-Yuh Ko; Kuen-Tyng Lin; Shu-Chen Lin; Pang-hsien Tu; Yuh-Shan Jou
Identification of oncogenic point mutations and hyperphosphorylation of anaplastic lymphoma kinase in lung cancer.
Neoplasia (New York, N.Y.) 2011;13(8):704-15.
2011: Tz-Chuen Ju; Jheng-Jie Kang; Jiun-Tsai Lin; Cheng-Pu Sun; Mi-Hua Tao; Pang-hsien Tu; Chen Chang; Ching-Pang Chang; Wei-Cheng Chang; Hui-Mei Chen; dennis dickson; Yijuang Chern
Nuclear translocation of AMPK-alpha1 potentiates striatal neurodegeneration in Huntington's disease.
The Journal of cell biology 2011;194(2):209-27.
2011: Li-Hsin Chen; Che-Chuan Loong; Tsann-Long Su; Yi-Jang Lee; Pei-Ming Chu; Ming-Long Tsai; Ping-Hsin Tsai; Pang-hsien Tu; Chin-Wen Chi; Hsin-Chen Lee; Shih-Hwa Chiou
Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway.
Biochemical pharmacology 2011;81(5):594-605.
2011: Ching-Paio Tsai; Bing-Wen Soong; Kon-Ping Lin; Pang-hsien Tu; Jer-Li Lin; Yi-Chung Lee
FUS, TARDBP, and SOD1 mutations in a Taiwanese cohort with familial ALS.
Neurobiology of aging 2011;32(3):553.e13-21.
2011: Pei-Ming Chu; Shih-Hwa Chiou; Tsann-Long Su; Yi-Jang Lee; Li-Hsin Chen; Yi-Wei Chen; Sang-Hue Yen; Ming-Teh Chen; Ming-Hsiung Chen; Yang-Hsin Shih; Pang-hsien Tu; Hsin-I Ma
Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response.
Radiation oncology (London, England) 2011;6():7.
2010: Chian-Feng Chen; En-Chi Hsu; Kuen-Tyng Lin; Pang-hsien Tu; Hung-Wei Chang; Chin-Hui Lin; Yann-Jang Chen; De-Leung Gu; Chi-Hung Lin; Jer-Yuarn Wu; Yuan-Tsong Chen; Ming-Ta Hsu; Yuh-Shan Jou
Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2010;52(5):1690-701.
2010: Allan K-H Chen; Ryan Y-Y Lin; Eva Z-J Hsieh; Pang-hsien Tu; Rita P-Y Chen; Tai-Yan Liao; Wenlung Chen; Chih-Hsien Wang; Joseph J-T Huang
Induction of amyloid fibrils by the C-terminal fragments of TDP-43 in amyotrophic lateral sclerosis.
Journal of the American Chemical Society 2010;132(4):1186-7.
2008: Szu-Yi Chou; Ju-Yun Weng; Hsing-Lin Lai; Fang Liao; Synthia H Sun; Pang-hsien Tu; dennis dickson; Yijuang Chern
Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(13):3277-90.
2007: Maria I Behrens; Odity Mukherjee; Pang-hsien Tu; Rajka Liscic; Lea Tenenholz Grinberg; Deborah Carter; Katherine Paulsmeyer; Lisa Taylor-Reinwald; Michael Gitcho; Joanne B Norton; Sumi Chakraverty; Alison Goate; John C Morris; Nigel J Cairns
Neuropathologic heterogeneity in HDDD1: a familial frontotemporal lobar degeneration with ubiquitin-positive inclusions and progranulin mutation.
Alzheimer disease and associated disorders 2007;21(1):1-7.
2006: Odity Mukherjee; Pau Pastor; Nigel J Cairns; Sumi Chakraverty; John S K Kauwe; Shantia Shears; Maria I Behrens; John Budde; Anthony L Hinrichs; Joanne Norton; Denise Levitch; Lisa Taylor-Reinwald; Michael Gitcho; Pang-hsien Tu; Lea Tenenholz Grinberg; Rajka Liscic; Javier Armendariz; John C Morris; Alison Goate
HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulin.
Annals of neurology 2006;60(3):314-22.
2006: Andrew J Hope; David B Mansur; Pang-hsien Tu; Joseph R Simpson
Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2006;22(9):1201-7.
2006: Mark S Forman; Ian R A Mackenzie; Nigel J Cairns; Eric Swanson; Philip J Boyer; David Drachman; Bharati S Jhaveri; Jason H T Karlawish; Alan Pestronk; Thomas W Smith; Pang-hsien Tu; Giles D J Watts; William R Markesbery; Charles D Smith; Virginia E Kimonis
Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations.
Journal of neuropathology and experimental neurology 2006;65(6):571-81.
2005: Pang-hsien Tu; Caterina Giannini; Alexander R Judkins; Jason M Schwalb; Richard Burack; Brian P O'Neill; Anthony T Yachnis; Peter C Burger; Bernd W Scheithauer; Arie Perry
Clinicopathologic and genetic profile of intracranial marginal zone lymphoma: a primary low-grade CNS lymphoma that mimics meningioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(24):5718-27.
2005: William Ashley; Prithvi Narayan; Tae Sung Park; Pang-hsien Tu; Arie Perry; Jeffrey R Leonard
Incidental pediatric intraparenchymal xanthogranuloma: case report and review of the literature.
Journal of neurosurgery 2005;102(3 Suppl):307-10.
2005: Eyas M Hattab; Pang-hsien Tu; Jon D Wilson; Liang Cheng
OCT4 immunohistochemistry is superior to placental alkaline phosphatase (PLAP) in the diagnosis of central nervous system germinoma.
The American journal of surgical pathology 2005;29(3):368-71.
2005: Oxana Kloub; Arie Perry; Pang-hsien Tu; Maurice H Lipper; M Beatriz S Lopes
Spindle cell oncocytoma of the adenohypophysis: report of two recurrent cases.
The American journal of surgical pathology 2005;29(2):247-53.
1999: Scott T Brady; AS Witt; L L Kirkpatrick; S M de Waegh; C Readhead; Pang-hsien Tu; Virginia M-Y Lee
Formation of compact myelin is required for maturation of the axonal cytoskeleton.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(17):7278-88.
1999: Gregory A Elder; Victor L Friedrich; D Pereira; Pang-hsien Tu; B Zhang; Virginia M-Y Lee; Robert A Lazzarini
Mice with disrupted midsized and heavy neurofilament genes lack axonal neurofilaments but have unaltered numbers of axonal microtubules.
Journal of neuroscience research 1999;57(1):23-32.
1999: James E Galvin; Virginia M-Y Lee; M Luise Schmidt; Pang-hsien Tu; Takeshi Iwatsubo; John Q Trojanowski
Pathobiology of the Lewy body.
Advances in neurology 1999;80():313-24.
1998: Gregory A Elder; Victor L Friedrich; C Kang; P Bosco; A Gourov; Pang-hsien Tu; B Zhang; Virginia M-Y Lee; Robert A Lazzarini
Requirement of heavy neurofilament subunit in the development of axons with large calibers.
The Journal of cell biology 1998;143(1):195-205.
1998: Pang-hsien Tu; James E Galvin; M Baba; Benoit I Giasson; Taisuke Tomita; Susan Leight; S Nakajo; Takeshi Iwatsubo; John Q Trojanowski; Virginia M-Y Lee
Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.
Annals of neurology 1998;44(3):415-22.
1998: Gregory A Elder; Victor L Friedrich; P Bosco; C Kang; A Gourov; Pang-hsien Tu; Virginia M-Y Lee; Robert A Lazzarini
Absence of the mid-sized neurofilament subunit decreases axonal calibers, levels of light neurofilament (NF-L), and neurofilament content.
The Journal of cell biology 1998;141(3):727-39.
1998: M Baba; S Nakajo; Pang-hsien Tu; Taisuke Tomita; K Nakaya; Virginia M-Y Lee; John Q Trojanowski; Takeshi Iwatsubo
Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.
The American journal of pathology 1998;152(4):879-84.
1997: Pang-hsien Tu; M E Gurney; J P Julien; Virginia M-Y Lee; John Q Trojanowski
Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease.
Laboratory investigation; a journal of technical methods and pathology 1997;76(4):441-56.
1997: Pang-hsien Tu; K A Robinson; F de Snoo; Joël Eyer; A Peterson; Virginia M-Y Lee; John Q Trojanowski
Selective degeneration fo Purkinje cells with Lewy body-like inclusions in aged NFHLACZ transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(3):1064-74.
1996: Pang-hsien Tu; P Raju; K A Robinson; M E Gurney; John Q Trojanowski; Virginia M-Y Lee
Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):3155-60.
1995: Pang-hsien Tu; Gregory A Elder; Robert A Lazzarini; D Nelson; John Q Trojanowski; Virginia M-Y Lee
Overexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunits.
The Journal of cell biology 1995;129(6):1629-40.