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Michael Routledge

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Clara Ersson; Magdalena Ferlinska; Lykke Forchhammer; Roger Godschalk; Jennifer A Higgins; George D D Jones; Mahsa Karbaschi; Blanca Laffon; Steffen Loft; Adela López de Cerain; Giuseppe Matullo; Vilas Mistry; Peter Møller; Kirsty Nelson-Smith; David H Phillips; Marisa Porrini; Patrizia Riso; Michael Routledge; Osman Sozeri; Maciej Stepnik; João Paulo Teixeira; Vanessa Valdiglesias; Frederik-Jan van Schooten; Alessandra Allione; Amaia Azqueta; Andrew R Collins; Marcus S Cooke; Laura-Ana Corcuera; Solange Costa; Lennart Möller
An ECVAG inter-laboratory validation study of the comet assay: inter-laboratory and intra-laboratory variations of DNA strand breaks and FPG-sensitive sites in human mononuclear cells.
Lykke Forchhammer; Roger Godschalk; Jennifer A Higgins; George D D Jones; Mahsa Karbaschi; Magdalena Komorowska; Blanca Laffon; Steffen Loft; Adela López de Cerain; Giuseppe Matullo; Vilas Mistry; Lennart Möller; Kirsty Nelson-Smith; David H Phillips; Marisa Porrini; Patrizia Riso; Michael Routledge; Osman Sozeri; Maciej Steepnik; João Paulo Teixeira; Vanessa Valdiglesias; Frederik J Van Schooten; Maciej Stępnik; Alessandra Allione; Amaia Azqueta; Andrew R Collins; Marcus Cooke; Laura-Ana Corcuera; Solange Costa; Clara Ersson; Peter Møller
Inter-laboratory variation in DNA damage using a standard comet assay protocol.
Qingshan Mu; Andy P Brown; Nicole S Hondow; Lars J C Jeuken; Lukasz Krzemiński; Michael Routledge
Mechanism of cellular uptake of genotoxic silica nanoparticles.

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All Publications

2013: Clara Ersson; Magdalena Ferlinska; Lykke Forchhammer; Roger Godschalk; Jennifer A Higgins; George D D Jones; Mahsa Karbaschi; Blanca Laffon; Steffen Loft; Adela López de Cerain; Giuseppe Matullo; Vilas Mistry; Peter Møller; Kirsty Nelson-Smith; David H Phillips; Marisa Porrini; Patrizia Riso; Michael Routledge; Osman Sozeri; Maciej Stepnik; João Paulo Teixeira; Vanessa Valdiglesias; Frederik-Jan van Schooten; Alessandra Allione; Amaia Azqueta; Andrew R Collins; Marcus S Cooke; Laura-Ana Corcuera; Solange Costa; Lennart Möller
An ECVAG inter-laboratory validation study of the comet assay: inter-laboratory and intra-laboratory variations of DNA strand breaks and FPG-sensitive sites in human mononuclear cells.
Mutagenesis 2013;28(3):279-86.
2012: Lykke Forchhammer; Roger Godschalk; Jennifer A Higgins; George D D Jones; Mahsa Karbaschi; Magdalena Komorowska; Blanca Laffon; Steffen Loft; Adela López de Cerain; Giuseppe Matullo; Vilas Mistry; Lennart Möller; Kirsty Nelson-Smith; David H Phillips; Marisa Porrini; Patrizia Riso; Michael Routledge; Osman Sozeri; Maciej Steepnik; João Paulo Teixeira; Vanessa Valdiglesias; Frederik J Van Schooten; Maciej Stępnik; Alessandra Allione; Amaia Azqueta; Andrew R Collins; Marcus Cooke; Laura-Ana Corcuera; Solange Costa; Clara Ersson; Peter Møller
Inter-laboratory variation in DNA damage using a standard comet assay protocol.
Mutagenesis 2012;27(6):665-72.
2012: Qingshan Mu; Andy P Brown; Nicole S Hondow; Lars J C Jeuken; Lukasz Krzemiński; Michael Routledge
Mechanism of cellular uptake of genotoxic silica nanoparticles.
Particle and fibre toxicology 2012;9():29.
2010: Clara Johansson; Peter Møller; Lykke Forchhammer; Steffen Loft; Roger Godschalk; Sabine A S Langie; Stijn Lumeij; George D D Jones; Rachel W L Kwok; Amaya Azqueta; David H Phillips; Osman Sozeri; Michael Routledge; Alexander J Charlton; Patrizia Riso; Marisa Porrini; Alessandra Allione; Giuseppe Matullo; Jadwiga Palus; Maciej Stepnik; Andrew R Collins; Lennart Möller
An ECVAG trial on assessment of oxidative damage to DNA measured by the comet assay.
Mutagenesis 2010;25(2):125-32.
2010: Sofian Metassan; Michael Routledge; Andrew J Lucking; Shirley Uitte de Willige; Helen Philippou; Nicholas L Mills; David E Newby; Robert A S Ariëns
Fibrin clot structure remains unaffected in young, healthy individuals after transient exposure to diesel exhaust.
Particle and fibre toxicology 2010;7():17.
2008: Charlotta Ryk; Michael Routledge; James M Allan; Christopher P Wild; Rajiv Kumar; Bo Lambert; Saimei Hou
Influence of DNA repair gene polymorphisms on the initial repair of MMS-induced DNA damage in human lymphocytes as measured by the alkaline comet assay.
Environmental and molecular mutagenesis 2008;49(9):669-75.
2008: P D Lewis; B Manshian; Michael Routledge; G B Scott; P A Burns
Comparison of induced and cancer-associated mutational spectra using multivariate data analysis.
Carcinogenesis 2008;29(4):772-8.
2007: Nicole T Watt; Michael Routledge; Christopher P Wild; Nigel M Hooper
Cellular prion protein protects against reactive-oxygen-species-induced DNA damage.
Free radical biology & medicine 2007;43(6):959-67.
2007: Tom G Hopkins; Philip A Burns; Michael Routledge
DNA methylation of GSTP1 as biomarker in diagnosis of prostate cancer.
Urology 2007;69(1):11-6.
2007: J Davies; D Burke; Joanna R Olliver; Laura J Hardie; Christopher P Wild; Michael Routledge
Methylene blue but not indigo carmine causes DNA damage to colonocytes in vitro and in vivo at concentrations used in clinical chromoendoscopy.
Gut 2007;56(1):155-6.
2006: Katherine Healey; Elizabeth C Smith; Christopher P Wild; Michael Routledge
The mutagenicity of urban particulate matter in an enzyme free system is associated with the generation of reactive oxygen species.
Mutation research 2006;602(1-2):1-6.
2005: Rebecca A Crallan; Eileen Ingham; Michael Routledge
Wavelength dependent responses of primary human keratinocytes to combined treatment with benzo[a]pyrene and UV light.
Mutagenesis 2005;20(4):305-10.
2005: Keith McLuckie; Robert J R Crookston; Margaret Gaskell; Peter B Farmer; Michael Routledge; Elizabeth A Martin; Karen Brown
Mutation spectra induced by alpha-acetoxytamoxifen-DNA adducts in human DNA repair proficient and deficient (xeroderma pigmentosum complementation group A) cells.
Biochemistry 2005;44(22):8198-205.
2005: Katherine Healey; Justin J N Lingard; Alison S Tomlin; Adam Hughes; K L M White; Christopher P Wild; Michael Routledge
Genotoxicity of size-fractionated samples of urban particulate matter.
Environmental and molecular mutagenesis 2005;45(4):380-7.
2004: Keith McLuckie; Margaret Gaskell; Peter B Farmer; Elizabeth A Martin; George D D Jones; Michael Routledge
Effects of the order of exposure to a binary mixture of mutagens on the induced mutation spectra in the supF gene.
Mutagenesis 2004;19(2):137-41.
2003: Csilla Misl'anová; Katherine Healey; K L M White; Elizabeth C Smith; Laura J Hardie; Mária Dusinská; Christopher P Wild; Michael Routledge
Binary exposure of A549 cells to benzo[a]pyrene and UVC radiation yields enhanced DNA damage in the comet assay but no enhancement of 8-oxo-deoxyguanosine.
Environmental and molecular mutagenesis 2003;42(3):228-30.
2002: Keith McLuckie; Michael Routledge; Karen Brown; Margaret Gaskell; Peter B Farmer; Gordon Roberts; Elizabeth A Martin
DNA adducts formed from 4-hydroxytamoxifen are more mutagenic than those formed by alpha-acetoxytamoxifen in a shuttle vector target gene replicated in human Ad293 cells.
Biochemistry 2002;41(28):8899-906.
2002: William P Patton; Michael Routledge; George D D Jones; Sheena E M Lewis; Desmond B Archer; R Jeremy H Davies; Usha Chakravarthy
Retinal pigment epithelial cell DNA is damaged by exposure to benzo[a]pyrene, a constituent of cigarette smoke.
Experimental eye research 2002;74(4):513-22.
2001: Michael Routledge; Keith McLuckie; George D D Jones; Peter B Farmer; Elizabeth A Martin
Presence of benzo[a]pyrene diol epoxide adducts in target DNA leads to an increase in UV-induced DNA single strand breaks and supF gene mutations.
Carcinogenesis 2001;22(8):1231-8.
2000: Michael Routledge
Mutations induced by reactive nitrogen oxide species in the supF forward mutation assay.
Mutation research 2000;450(1-2):95-105.
1999: George D D Jones; L Dickinson; Joseph Lunec; Michael Routledge
SVPD-post-labeling detection of oxidative damage negates the problem of adventitious oxidative effects during 32P-labeling.
Carcinogenesis 1999;20(3):503-7.
1997: Michael Routledge; James M Allan; R Colin Garner
Detection of DNA damage by Escherichia coli UvrB-binding competition assay is limited by the stability of the UvrB-DNA complex.
Carcinogenesis 1997;18(7):1407-13.
1996: J M Allan; Michael Routledge; R Colin Garner
The Escherichia coli DNA repair protein UvrA can re-associate with the UvrB: aflatoxin B1-DNA complex in vitro.
Mutation research 1996;362(3):261-8.
1994: Michael Routledge; F J Mirsky; David A Wink; L K Keefer; Anthony Dipple
Nitrite-induced mutations in a forward mutation assay: influence of nitrite concentration and pH.
Mutation research 1994;322(4):341-6.
1994: Michael Routledge; David A Wink; L K Keefer; Anthony Dipple
DNA sequence changes induced by two nitric oxide donor drugs in the supF assay.
Chemical research in toxicology 1994;7(5):628-32.
1994: J Szeliga; H Lee; R G Harvey; JE Page; H L Ross; Michael Routledge; B D Hilton; Anthony Dipple
Reaction with DNA and mutagenic specificity of syn-benzo[g]chrysene 11,12-dihydrodiol 13,14-epoxide.
Chemical research in toxicology 1994;7(3):420-7.
1993: Paul T Strickland; Michael Routledge; Anthony Dipple
Methodologies for measuring carcinogen adducts in humans.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1993;2(6):607-19.
1993: M M King; Jack Cuzick; D Jenkins; Michael Routledge; R Colin Garner
Immunoaffinity concentration of human lung DNA adducts using an anti-benzo[a]pyrene-diol-epoxide-DNA antibody. Analysis by 32P-postlabelling or ELISA.
Mutation research 1993;292(2):113-22.
1993: Michael Routledge; David A Wink; L K Keefer; Anthony Dipple
Mutations induced by saturated aqueous nitric oxide in the pSP189 supF gene in human Ad293 and E. coli MBM7070 cells.
Carcinogenesis 1993;14(7):1251-4.
1992: Michael Routledge; R Colin Garner; M Kirsch-Volders
Comparison of 32P-postlabelling and cytogenetic analysis of human blood treated in vitro with melphalan.
Mutagenesis 1992;7(5):329-33.
1992: Michael Routledge; R Colin Garner; D Jenkins; Jack Cuzick
32P-postlabelling analysis of DNA from human tissues.
Mutation research 1992;282(3):139-45.
1990: Jack Cuzick; Michael Routledge; D Jenkins; R Colin Garner
DNA adducts in different tissues of smokers and non-smokers.
International journal of cancer. Journal international du cancer 1990;45(4):673-8.
1990: Michael Routledge; Terry C Orton; Peter Lord; R Colin Garner
Effect of butylated hydroxyanisole on the level of DNA adduction by aristolochic acid in the rat forestomach and liver.
Japanese journal of cancer research : Gann 1990;81(3):220-4.
1990: R Colin Garner; Jack Cuzick; D Jenkins; D H Phillips; A Hewer; M M King; Michael Routledge
Linear relationship between DNA adducts in human lung and cigarette smoking.
IARC scientific publications 1990;(104):421-6.
1989: L A Iwanejko; Michael Routledge; GS Stewart
Cloning in Escherichia coli of the enterotoxin gene from Clostridium perfringens type A.
Journal of general microbiology 1989;135(4):903-9.