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Curt Mazur

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Clotilde Lagier-Tourenne; Tiffany Y Liang; Shuo-Chien Ling; Curt Mazur; Magdalini Polymenidou; John Ravits; Lily Shiue; Anthony Q Vu; Edward V Wancewicz; Andy Watt; Michael Baughn; C Frank Bennett; Don W Cleveland; Kevin M Clutario; John Paul Donohue; Sue Freier; Geoffrey G Hicks; Stephanie C Huelga; Kasey R Hutt; Aneeza S Kim; Gene Yeo
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.
Holly B Kordasiewicz; Curt Mazur; Melissa M McAlonis; Kimberly A Pytel; Lamya S Shihabuddin; Lisa M Stanek; Edward V Wancewicz; Andreas Weiss; Jonathan W Artates; C Frank Bennett; Seng H Cheng; Gene Hung; Don W Cleveland
Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.
Devin M Swanson; Chandra R Shah; Brian Lord; Kirsten Morton; Lisa K Dvorak; Curt Mazur; Richard Apodaca; Wei Xiao; Jamin D Boggs; Mark Feinstein; Sandy J Wilson; Ann J Barbier; Pascal Bonaventure; Timothy W Lovenberg; Nicholas I Carruthers
Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.

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All Publications

2012: Clotilde Lagier-Tourenne; Tiffany Y Liang; Shuo-Chien Ling; Curt Mazur; Magdalini Polymenidou; John Ravits; Lily Shiue; Anthony Q Vu; Edward V Wancewicz; Andy Watt; Michael Baughn; C Frank Bennett; Don W Cleveland; Kevin M Clutario; John Paul Donohue; Sue Freier; Geoffrey G Hicks; Stephanie C Huelga; Kasey R Hutt; Aneeza S Kim; Gene Yeo
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.
Nature neuroscience 2012;15(11):1488-97.
2012: Holly B Kordasiewicz; Curt Mazur; Melissa M McAlonis; Kimberly A Pytel; Lamya S Shihabuddin; Lisa M Stanek; Edward V Wancewicz; Andreas Weiss; Jonathan W Artates; C Frank Bennett; Seng H Cheng; Gene Hung; Don W Cleveland
Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.
Neuron 2012;74(6):1031-44.
2009: Devin M Swanson; Chandra R Shah; Brian Lord; Kirsten Morton; Lisa K Dvorak; Curt Mazur; Richard Apodaca; Wei Xiao; Jamin D Boggs; Mark Feinstein; Sandy J Wilson; Ann J Barbier; Pascal Bonaventure; Timothy W Lovenberg; Nicholas I Carruthers
Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.
European journal of medicinal chemistry 2009;44(11):4413-25.
2009: Ying Qu; Leah Aluisio; Brian Lord; Jamin Boggs; Kenway Hoey; Curt Mazur; Timothy Lovenberg
Pharmacokinetics and pharmacodynamics of norfluoxetine in rats: Increasing extracellular serotonin level in the frontal cortex.
Pharmacology, biochemistry, and behavior 2009;92(3):469-73.
2009: JIll Jablonowski; Kiev S Ly; Michael Bogenstaetter; Curt A Dvorak; Jamin D Boggs; Lisa K Dvorak; Brian Lord; Kirsten L Miller; Curt Mazur; Sandy J Wilson; Timothy W Lovenberg; Nicholas I Carruthers
Novel imidazole-based histamine H3 antagonists.
Bioorganic & medicinal chemistry letters 2009;19(3):903-7.
2009: Changlu Liu; Jiejun Wu; Jessica Zhu; Chester Kuei; Jingxue Yu; Jonathan Shelton; Steven W Sutton; Xiaorong Li; su jin yun; Taraneh Mirzadegan; Curt Mazur; Fredrik Kamme; Timothy W Lovenberg
Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81.
The Journal of biological chemistry 2009;284(5):2811-22.
2007: Ann J Barbier; Leah Aluisio; Brian Lord; Ying Qu; Sandy J Wilson; Jamin D Boggs; Pascal Bonaventure; Kirsten Miller; Ian Fraser; Lisa Dvorak; Cindy Pudiak; Christine Dugovic; Jonathan Shelton; Curt Mazur; Michael A Letavic; Nicholas I Carruthers; Timothy W Lovenberg
Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor.
European journal of pharmacology 2007;576(1-3):43-54.
2007: John M Keith; Ann J Barbier; Sandy J Wilson; Kirstin Miller; Jamin D Boggs; Ian C Fraser; Curt Mazur; Timothy W Lovenberg; Nicholas I Carruthers
Dual serotonin transporter inhibitor/histamine H3 antagonists: development of rigidified H3 pharmacophores.
Bioorganic & medicinal chemistry letters 2007;17(19):5325-9.
2007: John M Keith; Leslie A Gomez; Ann J Barbier; Sandy J Wilson; Jamin D Boggs; Brian Lord; Curt Mazur; Leah Aluisio; Timothy W Lovenberg; Nicholas I Carruthers
Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H3 antagonist and serotonin transporter inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(15):4374-7.
2007: John M Keith; Leslie A Gomez; Ronald L Wolin; Ann J Barbier; Sandy J Wilson; Jamin D Boggs; Curt Mazur; Ian C Fraser; Brian Lord; Leah Aluisio; Timothy W Lovenberg; Nicholas I Carruthers
Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(9):2603-7.
2007: Pascal Bonaventure; Michael A Letavic; Christine Dugovic; S Wilson; Leah Aluisio; Cindy Pudiak; Brian Lord; Curt Mazur; Fredrik Kamme; S Nishino; Nicholas I Carruthers; Timothy W Lovenberg
Histamine H3 receptor antagonists: from target identification to drug leads.
Biochemical pharmacology 2007;73(8):1084-96.
2007: John M Keith; Leslie A Gomez; Michael A Letavic; Kiev S Ly; JIll Jablonowski; Mark Seierstad; Ann J Barbier; Sandy J Wilson; Jamin D Boggs; Ian C Fraser; Curt Mazur; Timothy W Lovenberg; Nicholas I Carruthers
Dual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore.
Bioorganic & medicinal chemistry letters 2007;17(3):702-6.
2005: Jingcai Chen; Chester Kuei; Steven Sutton; Sandy Wilson; Jingxue Yu; Fredrik Kamme; Curt Mazur; Timothy W Lovenberg; Changlu Liu
Identification and pharmacological characterization of prokineticin 2 beta as a selective ligand for prokineticin receptor 1.
Molecular pharmacology 2005;67(6):2070-6.
2005: Devin M Swanson; Adrienne E Dubin; Chandra Shah; Nadia Nasser; Leon Chang; Scott L Dax; Michele C Jetter; J Guy Breitenbucher; Changlu Liu; Curt Mazur; Brian Lord; Lisa Gonzales; Kenway Hoey; Michele Rizzolio; Michael Bogenstaetter; Ellen E Codd; Doo H Lee; Sui-Po Zhang; Sandra R Chaplan; Nicholas I Carruthers
Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist.
Journal of medicinal chemistry 2005;48(6):1857-72.
2004: Ann J Barbier; C Berridge; Christine Dugovic; Aaron D Laposky; Sandy J Wilson; Jamin D Boggs; Leah Aluisio; Brian Lord; Curt Mazur; Cindy Pudiak; Xavier Langlois; Wei Xiao; Richard Apodaca; Nicholas I Carruthers; Timothy W Lovenberg
Acute wake-promoting actions of JNJ-5207852, a novel, diamine-based H3 antagonist.
British journal of pharmacology 2004;143(5):649-61.
2004: Peter B Hedlund; Lisa Kelly; Curt Mazur; Timothy W Lovenberg; J Gregor Sutcliffe; Pascal Bonaventure
8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents.
European journal of pharmacology 2004;487(1-3):125-32.
2004: Pascal Bonaventure; Diane Nepomuceno; Curt Mazur; Brian Lord; Dale A Rudolph; JIll Jablonowski; Nicholas I Carruthers; Timothy W Lovenberg
Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor.
The Journal of pharmacology and experimental therapeutics 2004;308(3):1130-7.
2003: Wenying Chai; J Guy Breitenbucher; Annette Kwok; Xiaobing Li; Victoria Wong; Nicholas I Carruthers; Timothy W Lovenberg; Curt Mazur; Sandy J Wilson; Frank U Axe; Todd K Jones
Non-imidazole heterocyclic histamine H3 receptor antagonists.
Bioorganic & medicinal chemistry letters 2003;13(10):1767-70.
2002: Chandra Shah; Laura C McAtee; J Guy Breitenbucher; Dale A Rudolph; Xiaobing Li; Timothy W Lovenberg; Curt Mazur; Sandy J Wilson; Nicholas I Carruthers
Novel human histamine H(3) receptor antagonists.
Bioorganic & medicinal chemistry letters 2002;12(22):3309-12.
2000: Takeo Abumiya; R Fitridge; Curt Mazur; BR Copeland; James A Koziol; J F Tschopp; M D Pierschbacher; Gregory J del Zoppo
Integrin alpha(IIb)beta(3) inhibitor preserves microvascular patency in experimental acute focal cerebral ischemia.
Stroke; a journal of cerebral circulation 2000;31(6):1402-09; discussion 1409-10.
1994: Curt Mazur; J F Tschopp; E C Faliakou; K E Gould; J T Diehl; M D Pierschbacher; R J Connolly
Selective alpha IIb beta 3 receptor blockage with peptide TP9201 prevents platelet uptake on Dacron vascular grafts without significant effect on bleeding time.
The Journal of laboratory and clinical medicine 1994;124(4):589-99.
1994: J F Tschopp; Curt Mazur; K Gould; R Connolly; M D Pierschbacher
Inhibition of thrombosis by a selective fibrinogen receptor antagonist without effect on bleeding time.
Thrombosis and haemostasis 1994;72(1):119-24.
1994: J F Tschopp; W S Craig; J Tolley; J Blevitt; Curt Mazur; M D Pierschbacher
Therapeutic application of matrix biology.
Methods in enzymology 1994;245():556-69.