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Mohammad Azhar Kamal

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TOP 3
Muhammad Faisal Wadiwala; Mohammad Azhar Kamal
What is better antiplatelet agent to prevent recurrent stroke?
Quratulain Shaikh; Mohammad Azhar Kamal
HDL cholesterol--how do I raise my patients good cholesterol?
Muhammad Faisal Wadiwala; Ambreen Sonawalla; Mohammad Azhar Kamal
What is the role of free radical scavengers in acute stroke?

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All Publications

2012: Muhammad Faisal Wadiwala; Mohammad Azhar Kamal
What is better antiplatelet agent to prevent recurrent stroke?
JPMA. The Journal of the Pakistan Medical Association 2012;62(9):976-7.
2012: Quratulain Shaikh; Mohammad Azhar Kamal
HDL cholesterol--how do I raise my patients good cholesterol?
JPMA. The Journal of the Pakistan Medical Association 2012;62(6):623-4.
2012: Muhammad Faisal Wadiwala; Ambreen Sonawalla; Mohammad Azhar Kamal
What is the role of free radical scavengers in acute stroke?
JPMA. The Journal of the Pakistan Medical Association 2012;62(5):512-3.
2012: Quratulain Shaikh; Mohammad Azhar Kamal
My patient has a lot of variability in his blood pressure measurements? Should I be worried? What can I do which may be better?
JPMA. The Journal of the Pakistan Medical Association 2012;62(4):407-8.
2012: Farzin Majeed; Mohammad Azhar Kamal
Can community based interventions control hypertension in developing countries? What is the evidence from Pakistan?
JPMA. The Journal of the Pakistan Medical Association 2012;62(3):301-2.
2012: Maria Khan; Emmon Raza; Mohammad Azhar Kamal
My patient has an elevated hs-CRP. What does this mean? What should I do now?
JPMA. The Journal of the Pakistan Medical Association 2012;62(2):182-3.
2012: Emmon Raza; Mohammad Azhar Kamal
Recurrent non-aneurysmal, metastatic intraparenchymal haemorrhages following resection of atrial myxoma - case report and literature review.
BMJ case reports 2012;2012():.
2012: Shaista Anwar Sidddiqi; Mohammad Azhar Kamal
A new antiplatelet agent cilostazol--what is the evidence for its use and tolerability?
JPMA. The Journal of the Pakistan Medical Association 2012;62(1):78-9.
2012: Maria Khan; Anoosh Moin; Myda Najeeb; Emmon Raza; Dania Shujaat; Bilal Ahmed; Maryam Ahmed; Ahmed Arshad; Farid Khan; Mohammad Azhar Kamal
Functional, cognitive and psychological outcomes, and recurrent vascular events in Pakistani stroke survivors: a cross sectional study.
BMC research notes 2012;5():89.
2011: Shaista Anwar Siddiqi; Mohammad Azhar Kamal
Ambulatory blood pressure monitoring in stroke survivors: what do we add to the care of our patients?
JPMA. The Journal of the Pakistan Medical Association 2011;61(12):1250-1.
2011: Farzin Majeed; Mohammad Azhar Kamal
Can selective serotonin reuptake inhibitors (SSRI) improve motor recovery after stroke? What is the role of neuroplasticity?
JPMA. The Journal of the Pakistan Medical Association 2011;61(11):1147-8.
2011: Shaista Anwar Siddiqi; Mohammad Azhar Kamal
My patient's brain MRI has cerebral microbleeds--what does this finding mean?
JPMA. The Journal of the Pakistan Medical Association 2011;61(10):1029-30.
2011: Shaista Anwar Sidddiqi; Mohammad Azhar Kamal
Use of traditional Chinese medication for post-stroke recovery.
JPMA. The Journal of the Pakistan Medical Association 2011;61(9):933-4.
2011: Mohammad Azhar Kamal; T Lakshmi Narayan Reddy; A Mallareddy; S Prabhakar; S N C V L Pushpavalli; Ch Ratna Reddy; N Shankaraiah; P Venkat Reddy; M Janaki Ramaiah; Manika Pal-Bhadra
Synthesis and anticancer activity of chalcone-pyrrolobenzodiazepine conjugates linked via 1,2,3-triazole ring side-armed with alkane spacers.
European journal of medicinal chemistry 2011;46(9):3820-31.
2011: Maria Khan; Emmon Raza; Mohammad Azhar Kamal
What is the role of B-vitamins in stroke prevention in Pakistan?
JPMA. The Journal of the Pakistan Medical Association 2011;61(8):825-6.
2011: Mohammad Azhar Kamal; G Ramakrishna; P Raju; A V Subba Rao; A Viswanath; V Lakshma Nayak; Sistla Ramakrishna
Synthesis and anticancer activity of oxindole derived imidazo[1,5-a]pyrazines.
European journal of medicinal chemistry 2011;46(6):2427-35.
2011: Mohammad Azhar Kamal; Paidakula Suresh; Aarti Juvekar; B Ashwini Kumar; Surekha M Zingde
Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents.
Bioorganic & medicinal chemistry 2011;19(9):2975-9.
2011: Maria Khan; Mohammad Azhar Kamal
What modifiable risk factors lead to strokes in our part of the world?
JPMA. The Journal of the Pakistan Medical Association 2011;61(1):94-5.
2011: Maria Khan; Imama Naqvi; Asha Bansari; Mohammad Azhar Kamal
Intracranial atherosclerotic disease.
Stroke research and treatment 2011;2011():282845.
2011: Mohammad Azhar Kamal; Imama Naqvi; Muhammad R Husain; Bhojo A Khealani
Cilostazol versus aspirin for secondary prevention of vascular events after stroke of arterial origin.
Cochrane database of systematic reviews (Online) 2011;(1):CD008076.
2011: Mohammad Azhar Kamal; B Ashwini Kumar; Paidakula Suresh; N Shankaraiah; M Shiva Kumar
An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activity.
Bioorganic & medicinal chemistry letters 2011;21(1):350-3.
2010: Mohammad Azhar Kamal; D Dastagiri; M Janaki Ramaiah; E Vijaya Bharathi; J Surendranadha Reddy; G Balakishan; Pranjal Sarma; S N C V L Pushpavalli; Manika Pal-Bhadra; Aarti Juvekar; Subrata Sen; Surekha M Zingde
Synthesis, anticancer activity and mitochondrial mediated apoptosis inducing ability of 2,5-diaryloxadiazole-pyrrolobenzodiazepine conjugates.
Bioorganic & medicinal chemistry 2010;18(18):6666-77.
2010: Robbert G E Notenboom; Geert M J Ramakers; Mohammad Azhar Kamal; Berry M Spruijt; P N E De Graan
Long-lasting modulation of synaptic plasticity in rat hippocampus after early-life complex febrile seizures.
The European journal of neuroscience 2010;32(5):749-58.
2010: Mohammad Azhar Kamal; K Srinivasa Reddy; M Naseer A Khan; Rajesh V C R N C Shetti; M Janaki Ramaiah; S N C V L Pushpavalli; Chatla Srinivas; Manika Pal-Bhadra; Mukesh Chourasia; G Narahari Sastry; Aarti Juvekar; Surekha M Zingde; Madan Barkume
Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole-pyrrolo[2,1-c][1,4]benzodiazepine conjugates.
Bioorganic & medicinal chemistry 2010;18(13):4747-61.
2010: Mohammad Azhar Kamal; E Vijaya Bharathi; M Janaki Ramaiah; J Surendranadha Reddy; D Dastagiri; A Viswanath; Farheen Sultana; S N C V L Pushpavalli; Manika Pal-Bhadra; Aarti Juvekar; Subrata Sen; Surekha M Zingde
Synthesis, anticancer activity and apoptosis inducing ability of anthranilamide-PBD conjugates.
Bioorganic & medicinal chemistry letters 2010;20(11):3310-3.
2010: Mohammad Azhar Kamal; E Vijaya Bharathi; M Janaki Ramaiah; D Dastagiri; J Surendranadha Reddy; A Viswanath; Farheen Sultana; S N C V L Pushpavalli; Manika Pal-Bhadra; Hemant Kumar Srivastava; G Narahari Sastry; Aarti Juvekar; Subrata Sen; Surekha M Zingde
Quinazolinone linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates: Design, synthesis and biological evaluation as potential anticancer agents.
Bioorganic & medicinal chemistry 2010;18(2):526-42.
2009: Mohammad Azhar Kamal; D Rajasekhar Reddy; M Kashi Reddy; G Balakishan; T Basha Shaik; Mukesh Chourasia; G Narahari Sastry
Remarkable enhancement in the DNA-binding ability of C2-fluoro substituted pyrrolo[2,1-c][1,4]benzodiazepines and their anticancer potential.
Bioorganic & medicinal chemistry 2009;17(4):1557-72.
2009: Mohammad Azhar Kamal; Ahmed Itrat; Muhammed Murtaza; Maria Khan; Asif Rasheed; Amin Ali; Amna Akber; Zainab Akber; Naved Iqbal; Sana Shoukat; Farzin Majeed; Danish Saleheen
The burden of stroke and transient ischemic attack in Pakistan: a community-based prevalence study.
BMC neurology 2009;9():58.
2009: Sana Shoukat; Ahmed Itrat; Ather M Taqui; Moazzam Zaidi; Mohammad Azhar Kamal
Moyamoya disease: a clinical spectrum, literature review and case series from a tertiary care hospital in Pakistan.
BMC neurology 2009;9():15.
2008: Mohammad Azhar Kamal; P Praveen Kumar; K Sreekanth; B N Seshadri; P Ramulu
Synthesis of new benzimidazole linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates with efficient DNA-binding affinity and potent cytotoxicity.
Bioorganic & medicinal chemistry letters 2008;18(8):2594-8.
2008: Mohammad Azhar Kamal; N Shankaraiah; S Prabhakar; Ch Ratna Reddy; N Markandeya; K Laxma Reddy; V Devaiah
Solid-phase synthesis of new pyrrolobenzodiazepine-chalcone conjugates: DNA-binding affinity and anticancer activity.
Bioorganic & medicinal chemistry letters 2008;18(7):2434-9.
2008: Mohammad Azhar Kamal; P Praveen Kumar; B N Seshadri; O Srinivas; M Shiva Kumar; Subrata Sen; Nisha Kurian; Aarti Juvekar; Surekha M Zingde
Phosphonate-linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: synthesis, DNA-binding affinity and cytotoxicity.
Bioorganic & medicinal chemistry 2008;16(7):3895-906.
2008: Mohammad Azhar Kamal; N Shankaraiah; V Devaiah; K Laxma Reddy; Aarti Juvekar; Subrata Sen; Nisha Kurian; Surekha Zingde
Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing 'click' chemistry: DNA-binding affinity and anticancer activity.
Bioorganic & medicinal chemistry letters 2008;18(4):1468-73.
2008: Peter Sandercock; Carl Counsell; Mohammad Azhar Kamal
Anticoagulants for acute ischaemic stroke.
Cochrane database of systematic reviews (Online) 2008;(4):CD000024.
2008: Mohammad Azhar Kamal; M Naseer A Khan; K Srinivasa Reddy; Y V V Srikanth; Balasubramanian Sridhar
Synthesis, structural characterization and biological evaluation of novel [1,2,4]triazolo [1,5-b][1,2,4]benzothiadiazine-benzothiazole conjugates as potential anticancer agents.
Chemical biology & drug design 2008;71(1):78-86.
2007: Mohammad Azhar Kamal; Ravirala Ramu; Venkatesh Tekumalla; G B Ramesh Khanna; Madan S Barkume; Aarti Juvekar; Surekha M Zingde
Synthesis, DNA binding, and cytotoxicity studies of pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates.
Bioorganic & medicinal chemistry 2007;15(22):6868-75.
2007: Zarmeneh Aly; Fawad Taj; Mohammad Azhar Kamal
Reformulating the lacunae hypothesis.
JPMA. The Journal of the Pakistan Medical Association 2007;57(10):524.
2007: Mohammad Azhar Kamal; M Naseer A Khan; K Srinivasa Reddy; S Kaleem Ahmed; M Shiva Kumar; Aarti Juvekar; Subrata Sen; Surekha Zingde
1,2,4-benzothiadiazine linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: synthesis, DNA-binding affinity and cytotoxicity.
Bioorganic & medicinal chemistry letters 2007;17(19):5345-8.
2007: Mohammad Azhar Kamal; M Naseer A Khan; K Srinivasa Reddy; K Rohini; G Narahari Sastry; B Sateesh; Balasubramanian Sridhar
Synthesis, structure analysis, and antibacterial activity of some novel 10-substituted 2-(4-piperidyl/phenyl)-5,5-dioxo[1,2,4]triazolo[1,5-b][1,2,4]benzothiadiazine derivatives.
Bioorganic & medicinal chemistry letters 2007;17(19):5400-5.
2007: Mohammad Azhar Kamal; S Kaleem Ahmed; K Srinivasa Reddy; M Naseer A Khan; Rajesh V C R N C Shetty; B Siddhardha; U S N Murthy; Inshad Ali Khan; Manoj Kumar; Sandeep Sharma; Anshu Beulah Ram
Anti-tubercular agents. Part IV: Synthesis and antimycobacterial evaluation of nitroheterocyclic-based 1,2,4-benzothiadiazines.
Bioorganic & medicinal chemistry letters 2007;17(19):5419-22.
2007: Fawad Taj; Mohammad Azhar Kamal
Inflammatory biomarkers of stroke.
JPMA. The Journal of the Pakistan Medical Association 2007;57(7):381-2.
2007: Srinivas R Kasibhatla; Kevin Hong; Marco A Biamonte; David J Busch; Patricia L Karjian; John L Sensintaffar; Mohammad Azhar Kamal; Rachel E Lough; John Brekken; Karen Lundgren; Roy Grecko; Gregg A Timony; Yingqing Ran; Robert Mansfield; Lawrence C Fritz; Edgar Ulm; Francis Burrows; Marcus F Boehm
Rationally designed high-affinity 2-amino-6-halopurine heat shock protein 90 inhibitors that exhibit potent antitumor activity.
Journal of medicinal chemistry 2007;50(12):2767-78.
2007: Mohammad Azhar Kamal; V Devaiah; K Laxma Reddy; Rajesh V C R N C Shetti; N Shankaraiah
Efficient solid-phase synthesis of a library of imidazo[1,2-a]pyridine-8-carboxamides.
Journal of combinatorial chemistry 2007;9(2):267-74.
2007: Chad A Dickey; Mohammad Azhar Kamal; Karen Lundgren; Natalia Klosak; Rachel M Bailey; Judith Dunmore; Peter Ash; Sareh Shoraka; Jelena Zlatkovic; Christopher B Eckman; Winston Patterson; dennis dickson; N Stanley Nahman; Michael Hutton; Francis Burrows; Leonard Petrucelli
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins.
The Journal of clinical investigation 2007;117(3):648-58.
2007: Mohammad Azhar Kamal; D Rajasekhar Reddy; P S Murali Mohan Reddy
Synthesis and DNA-binding ability of C2R-fluoro substituted DC-81 and its dimers.
Bioorganic & medicinal chemistry letters 2007;17(3):803-6.
2007: Mohammad Azhar Kamal; M Naseer A Khan; K Srinivasa Reddy; K Rohini
Synthesis of a new class of 2-anilino substituted nicotinyl arylsulfonylhydrazides as potential anticancer and antibacterial agents.
Bioorganic & medicinal chemistry 2007;15(2):1004-13.
2007: Khadija Masood; Zohair J Gazzaz; Khalid Ismail; Khalid O Dhafar; Mohammad Azhar Kamal
Pattern of psychiatry morbidity during Hajj period at Al-Noor Specialist Hospital.
International journal of psychiatry in medicine 2007;37(2):163-72.
2007: Mohammad Azhar Kamal; K Laxma Reddy; V Devaiah; N Shankaraiah; G Suresh Kumar Reddy; Sadagopan Raghavan
Solid-phase synthesis of a library of pyrrolo[2,1-c][1,4]benzodiazepine-5,11-diones with potential antitubercular activity.
Journal of combinatorial chemistry 2007;9(1):29-42.
2006: Cinzia Dello Russo; Paul E Polak; Pilar Mercado; Alessandra Spagnolo; Anthony Sharp; Patricia Murphy; Mohammad Azhar Kamal; Francis Burrows; Lawrence C Fritz; Douglas L Feinstein
The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis.
Journal of neurochemistry 2006;99(5):1351-62.
2006: Fazeel Mukhtar Siddiqui; Mohammad Azhar Kamal
Complications associated with cerebral venous thrombosis.
JPMA. The Journal of the Pakistan Medical Association 2006;56(11):547-51.
2006: Saad Shafqat; Mohammad Azhar Kamal; Mohammad Wasay
Heparin in the treatment of cerebral venous thrombosis.
JPMA. The Journal of the Pakistan Medical Association 2006;56(11):541-3.
2006: Mohammad Azhar Kamal
Thrombolytic therapy in cerebral venous sinus thrombosis.
JPMA. The Journal of the Pakistan Medical Association 2006;56(11):538-40.
2006: Ahmed Itrat; Sana Shoukat; Mohammad Azhar Kamal
Pathophysiology of cerebral venous thrombosis--an overview.
JPMA. The Journal of the Pakistan Medical Association 2006;56(11):506-8.
2006: Fazeel Mukhtar Siddiqui; Mohammad Azhar Kamal
Incidence and epidemiology of cerebral venous thrombosis.
JPMA. The Journal of the Pakistan Medical Association 2006;56(11):485-7.
2006: Mohammad Wasay; Mohammad Azhar Kamal
Cerebral venous thrombosis: recent advances and need for an Asian registry.
JPMA. The Journal of the Pakistan Medical Association 2006;56(11):483-4.
2006: Lin Zhang; Junhua Fan; Khang Vu; Kevin Hong; Jean-Yves Le Brazidec; Jiandong Shi; Marco A Biamonte; David J Busch; Rachel E Lough; Roy Grecko; Yingqing Ran; John L Sensintaffar; Mohammad Azhar Kamal; Karen Lundgren; Francis Burrows; Robert Mansfield; Gregg A Timony; Edgar H Ulm; Srinivas R Kasibhatla; Marcus F Boehm
7'-substituted benzothiazolothio- and pyridinothiazolothio-purines as potent heat shock protein 90 inhibitors.
Journal of medicinal chemistry 2006;49(17):5352-62.
2006: Junghee Kang; Mohammad Azhar Kamal; Francis J Burrows; B Mark Evers; Dai H Chung
Inhibition of neuroblastoma xenograft growth by Hsp90 inhibitors.
Anticancer research 2006;26(3A):1903-8.
2006: Mohammad Azhar Kamal; Robbert G E Notenboom; P N E De Graan; Geert M J Ramakers
Persistent changes in action potential broadening and the slow afterhyperpolarization in rat CA1 pyramidal cells after febrile seizures.
The European journal of neuroscience 2006;23(8):2230-4.
2006: Chad A Dickey; Judith Dunmore; Bingwei Lu; Ji-Wu Wang; Wing C Lee; Mohammad Azhar Kamal; Francis Burrows; Christopher B Eckman; Michael Hutton; Leonard Petrucelli
HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(6):753-5.
2006: Mohammad Azhar Kamal; D Rajasekhar Reddy; P S M M Reddy
Synthesis and DNA-binding ability of pyrrolo[2,1-c][1,4]benzodiazepine-azepane conjugates.
Bioorganic & medicinal chemistry letters 2006;16(5):1160-3.
2006: Mohammad Azhar Kamal; Geert Jan Biessels; Willem Hendrik Gispen; Geert M J Ramakers
Synaptic transmission changes in the pyramidal cells of the hippocampus in streptozotocin-induced diabetes mellitus in rats.
Brain research 2006;1073-1074():276-80.
2006: Mohammad Azhar Kamal; K Srinivasa Reddy; S Kaleem Ahmed; M Naseer A Khan; Rakesh K Sinha; JS Yadav; Sudershan K Arora
Anti-tubercular agents. Part 3. Benzothiadiazine as a novel scaffold for anti-Mycobacterium activity.
Bioorganic & medicinal chemistry 2006;14(3):650-8.
2006: Marco A Biamonte; Jiandong Shi; Kevin Hong; David C Hurst; Lin Zhang; Junhua Fan; David J Busch; Patricia L Karjian; Angelica A Maldonado; John L Sensintaffar; Yong-Ching Yang; Mohammad Azhar Kamal; Rachel E Lough; Karen Lundgren; Francis Burrows; Gregg A Timony; Marcus F Boehm; Srinivas R Kasibhatla
Orally active purine-based inhibitors of the heat shock protein 90.
Journal of medicinal chemistry 2006;49(2):817-28.
2006: Mohammad Azhar Kamal; P S M M Reddy; D Rajasekhar Reddy; E Laxman
DNA binding potential and cytotoxicity of newly designed pyrrolobenzodiazepine dimers linked through a piperazine side-armed-alkane spacer.
Bioorganic & medicinal chemistry 2006;14(2):385-94.
2006: Mohammad Azhar Kamal; K Laxma Reddy; V Devaiah; N Shankaraiah; Maddamsetty V Rao
Recent advances in the solid-phase combinatorial synthetic strategies for the quinoxaline, quinazoline and benzimidazole based privileged structures.
Mini reviews in medicinal chemistry 2006;6(1):71-89.
2006: Mohammad Azhar Kamal; K Laxma Reddy; V Devaiah; N Shankaraiah; D Rajasekhar Reddy
Recent advances in the solid-phase combinatorial synthetic strategies for the benzodiazepine based privileged structures.
Mini reviews in medicinal chemistry 2006;6(1):53-69.
2006: ALAIN ARTOLA; Josefien C von Frijtag; Patrick C J Fermont; Willem Hendrik Gispen; Loes H Schrama; Mohammad Azhar Kamal; Berry M Spruijt
Long-lasting modulation of the induction of LTD and LTP in rat hippocampal CA1 by behavioural stress and environmental enrichment.
The European journal of neuroscience 2006;23(1):261-72.
2005: Mohammad Azhar Kamal; N Lakshmi Gayatri; D Rajasekhar Reddy; P S Murali Mohan Reddy; M Arifuddin; Sunanda G Dastidar; Anand K Kondapi; M Rajkumar
Synthesis and biological evaluation of new 4beta-anilino- and 4beta-imido-substituted podophyllotoxin congeners.
Bioorganic & medicinal chemistry 2005;13(22):6218-25.
2005: Siddiq Khalil; Mohammad Azhar Kamal; Shakeel Ahmed
Acute myocardial infarction in a patient with dextrocardia and situs inversus.
Journal of electrocardiology 2005;38(4):412-3.
2005: Januario E Castro; Carlos E Prada; Olivier Loria; Mohammad Azhar Kamal; Liguang Chen; Francis J Burrows; Thomas Kipps
ZAP-70 is a novel conditional heat shock protein 90 (Hsp90) client: inhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic leukemia.
Blood 2005;106(7):2506-12.
2005: Mohammad Azhar Kamal; Geert Jan Biessels; Geert M J Ramakers; Willim Hendrik Gispen
The effect of short duration streptozotocin-induced diabetes mellitus on the late phase and threshold of long-term potentiation induction in the rat.
Brain research 2005;1053(1-2):126-30.
2005: Lars van der Heide; Mohammad Azhar Kamal; ALAIN ARTOLA; Willem Hendrik Gispen; Geert M J Ramakers
Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner.
Journal of neurochemistry 2005;94(4):1158-66.
2005: Mohammad Azhar Kamal; S F Adil; M Arifuddin
Ultrasonic activated efficient method for the cleavage of epoxides with aromatic amines.
Ultrasonics sonochemistry 2005;12(6):429-31.
2005: ALAIN ARTOLA; Mohammad Azhar Kamal; Geert M J Ramakers; Geert Jan Biessels; Willem Hendrik Gispen
Diabetes mellitus concomitantly facilitates the induction of long-term depression and inhibits that of long-term potentiation in hippocampus.
The European journal of neuroscience 2005;22(1):169-78.
2005: Mohammad Azhar Kamal; A Hari Babu; Venkata Ramana; K Venkata Ramana; E Vijaya Bharathi; M Shiva Kumar
Synthesis of pyrrolo[2,1-c][1,4]benzodiazepines and their conjugates by azido reductive cyclization strategy as potential DNA-binding agents.
Bioorganic & medicinal chemistry letters 2005;15(10):2621-3.
2005: Jin Jun Luo; Mercedes Jacobson; Mohammad Azhar Kamal; S Ausim Azizi
Ethmoid abscess with findings simulating Weber syndrome.
Neurology 2005;64(7):1266.
2005: Chad A Dickey; Jason Eriksen; Mohammad Azhar Kamal; Francis Burrows; Srinivas Kasibhatla; Christopher B Eckman; Michael Hutton; Leonard Petrucelli
Development of a high throughput drug screening assay for the detection of changes in tau levels -- proof of concept with HSP90 inhibitors.
Current Alzheimer research 2005;2(2):231-8.
2005: Mohammad Azhar Kamal; Ahmad Ali Shaik; Rakesh Sinha; JS Yadav; Sudershan K Arora
Antitubercular agents. Part 2: new thiolactomycin analogues active against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 2005;15(7):1927-9.
2005: Mohammad Azhar Kamal; A Hari Babu; Venkata Ramana; Rakesh Sinha; JS Yadav; Sudershan K Arora
Antitubercular agents. Part 1: synthesis of phthalimido- and naphthalimido-linked phenazines as new prototype antitubercular agents.
Bioorganic & medicinal chemistry letters 2005;15(7):1923-6.
2005: Mohammad Azhar Kamal; V Devaiah; K Laxma Reddy; M Shiva Kumar
Synthesis and biological activity of fluoroquinolone-pyrrolo[2,1-c][1,4]benzodiazepine conjugates.
Bioorganic & medicinal chemistry 2005;13(6):2021-9.
2005: Mohammad Azhar Kamal; Roderick J Flower; Mauro Perretti
An overview of the effects of annexin 1 on cells involved in the inflammatory process.
Memórias do Instituto Oswaldo Cruz 2005;100 Suppl 1():39-47.
2005: Geert Jan Biessels; Mariël P ter Laak; Mohammad Azhar Kamal; Willem Hendrik Gispen
Effects of the Ca2+ antagonist nimodipine on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats.
Brain research 2005;1035(1):86-93.
2005: Mohammad Azhar Kamal; G B Ramesh Khanna; T Krishnaji; Ravirala Ramu
A new facile chemoenzymatic synthesis of levamisole.
Bioorganic & medicinal chemistry letters 2005;15(3):613-5.
2005: Daniel S Mathon; Heidi M B Lesscher; Mirjam A F M Gerrits; Mohammad Azhar Kamal; John E Pintar; A G P Schuller; Berry M Spruijt; J Peter H Burbach; Marten P Smidt; Jan M van Ree; Geert M J Ramakers
Increased gabaergic input to ventral tegmental area dopaminergic neurons associated with decreased cocaine reinforcement in mu-opioid receptor knockout mice.
Neuroscience 2005;130(2):359-67.
2004: Francis Burrows; Hong Zhang; Mohammad Azhar Kamal
Hsp90 activation and cell cycle regulation.
Cell cycle (Georgetown, Tex.) 2004;3(12):1530-6.
2004: Mohammad Azhar Kamal; P S M M Reddy; D Rajasekhar Reddy; E Laxman; Y L N Murthy
Synthesis of fluorinated analogues of SJG-136 and their DNA-binding potential.
Bioorganic & medicinal chemistry letters 2004;14(22):5699-702.
2004: Mohammad Azhar Kamal; G Ramesh; O Srinivas; P Ramulu; N Laxman; Tasneem Rehana; M Deepak; Sridhar Achary Malkaram; Hampapathalu Nagarajaram
Design, synthesis, and evaluation of mixed imine-amine pyrrolobenzodiazepine dimers with efficient DNA binding affinity and potent cytotoxicity.
Bioorganic & medicinal chemistry 2004;12(20):5427-36.
2004: Mohammad Azhar Kamal; Ravirala Ramu; G B Ramesh Khanna; Ajit Kumar Saxena; Mutiah Shanmugavel; Renu Moti Pandita
Pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates. Synthesis, DNA binding and cytotoxicity.
Bioorganic & medicinal chemistry letters 2004;14(19):4907-9.
2004: Mohammad Azhar Kamal; P Ramulu; O Srinivas; G Ramesh; P Praveen Kumar
Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity.
Bioorganic & medicinal chemistry letters 2004;14(18):4791-4.
2004: Mohammad Azhar Kamal; Mahendra Sandbhor; Ahmad Ali Shaik
Chemoenzymatic synthesis of (S) and (R)-propranolol and sotalol employing one-pot lipase resolution protocol.
Bioorganic & medicinal chemistry letters 2004;14(17):4581-3.
2004: Mohammad Azhar Kamal; O Srinivas; P Ramulu; G Ramesh; P Praveen Kumar; M Shiva Kumar
Synthesis and DNA binding affinity of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers.
Bioorganic & medicinal chemistry 2004;12(16):4337-50.
2004: Mohammad Azhar Kamal; O Srinivas; P Ramulu; G Ramesh; P Praveen Kumar
Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids as potential DNA-binding agents.
Bioorganic & medicinal chemistry letters 2004;14(15):4107-11.
2004: Mohammad Azhar Kamal; E Laxman; G B Ramesh Khanna; P S M M Reddy; Tasneem Rehana; M Arifuddin; K Neelima; Anand K Kondapi; Sunanda G Dastidar
Design, synthesis, biological evaluation and QSAR studies of novel bisepipodophyllotoxins as cytotoxic agents.
Bioorganic & medicinal chemistry 2004;12(15):4197-209.
2004: Jean-Yves Le Brazidec; Mohammad Azhar Kamal; David Busch; Lia Thao; Lin Zhang; Gregg A Timony; Roy Grecko; Katy Trent; Rachel E Lough; Tim Salazar; Samina Khan; Francis Burrows; Marcus F Boehm
Synthesis and biological evaluation of a new class of geldanamycin derivatives as potent inhibitors of Hsp90.
Journal of medicinal chemistry 2004;47(15):3865-73.
2004: Mohammad Azhar Kamal; Marcus F Boehm; Francis Burrows
Therapeutic and diagnostic implications of Hsp90 activation.
Trends in molecular medicine 2004;10(6):283-90.
2004: Mohammad Azhar Kamal; P S M M Reddy; D Rajasekhar Reddy
The effect of C2-fluoro group on the biological activity of DC-81 and its dimers.
Bioorganic & medicinal chemistry letters 2004;14(10):2669-72.
2004: Mohammad Azhar Kamal; G Ramesh; O Srinivas; P Ramulu
Synthesis and antitumour activity of pyrene-linked pyrrolo [2,1-c]benzodiazepine hybrids.
Bioorganic & medicinal chemistry letters 2004;14(2):471-4.
2004: Els J M van Dam; Mohammad Azhar Kamal; ALAIN ARTOLA; P N E De Graan; Willem Hendrik Gispen; Geert M J Ramakers
Group I metabotropic glutamate receptors regulate the frequency-response function of hippocampal CA1 synapses for the induction of LTP and LTD.
The European journal of neuroscience 2004;19(1):112-8.
2004: Aziz Ulug; Thomas Grünewald; Michael T Lin; Mohammad Azhar Kamal; Christopher G Filippi; Robert D Zimmerman; M Flint Beal
Diffusion tensor imaging in the diagnosis of primary lateral sclerosis.
Journal of magnetic resonance imaging : JMRI 2004;19(1):34-9.
2003: Mohammad Azhar Kamal; B Ashwini Kumar; M Arifuddin; Sunanda G Dastidar
Synthesis of 4beta-amido and 4beta-sulphonamido analogues of podophyllotoxin as potential antitumour agents.
Bioorganic & medicinal chemistry 2003;11(23):5135-42.
2003: Mohammad Azhar Kamal; P Ramulu; O Srinivas; G Ramesh
Synthesis and DNA-binding affinity of A-C8/C-C2 alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers.
Bioorganic & medicinal chemistry letters 2003;13(22):3955-8.
2003: Daniel S Mathon; Mohammad Azhar Kamal; Marten P Smidt; Geert M J Ramakers
Modulation of cellular activity and synaptic transmission in the ventral tegmental area.
European journal of pharmacology 2003;480(1-3):97-115.
2003: Mohammad Azhar Kamal; O Srinivas; P Ramulu; G Ramesh; P Praveen Kumar
Synthesis of novel C2 and C2-C8 linked pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide hybrids as DNA-binding agents.
Bioorganic & medicinal chemistry letters 2003;13(20):3577-81.
2003: Mohammad Azhar Kamal; P Ramulu; O Srinivas; G Ramesh
Synthesis of C-8 methanesulphonate substituted pyrrolobenzodiazepines as potential antitumour agents.
Bioorganic & medicinal chemistry letters 2003;13(20):3517-9.
2003: Mohammad Azhar Kamal; G Ramesh; P Ramulu; O Srinivas; Tasneem Rehana; Gurrala Sheelu
Design and synthesis of novel chrysene-linked pyrrolo[2,1-c][1,4]-benzodiazepine hybrids as potential DNA-binding agents.
Bioorganic & medicinal chemistry letters 2003;13(20):3451-4.
2003: Mohammad Azhar Kamal; Lia Thao; John L Sensintaffar; Lin Zhang; Marcus F Boehm; Lawrence C Fritz; Francis Burrows
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors.
Nature 2003;425(6956):407-10.
2003: Mohammad Azhar Kamal
Exploiting membrane trafficking pathways: cytoskeletal motors and cargo as targets for drug discovery.
Drug discovery today 2003;8(18):828-9.
2003: Mohammad Azhar Kamal; Jonathan P Dyke; Jeffrey M Katz; Bernardo Liberato; Christopher G Filippi; Robert D Zimmerman; Aziz Ulug
Temporal evolution of diffusion after spontaneous supratentorial intracranial hemorrhage.
AJNR. American journal of neuroradiology 2003;24(5):895-901.
2003: Patrick J G H Kamphuis; Fabrizio Gardoni; Mohammad Azhar Kamal; Gerda Croiset; Joost M Bakker; Flaminio Nicola Cattabeni; Willem Hendrik Gispen; Frank van Bel; Monica Di Luca; Victor M Wiegant
Long-lasting effects of neonatal dexamethasone treatment on spatial learning and hippocampal synaptic plasticity: involvement of the NMDA receptor complex.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(8):911-3.
2003: Sanne M Manschot; Geert Jan Biessels; Norman E Cameron; Mary A Cotter; Mohammad Azhar Kamal; L Jaap Kappelle; Willem Hendrik Gispen
Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats.
Brain research 2003;966(2):274-82.
2003: Mohammad Azhar Kamal; Geert M J Ramakers; Geert Jan Biessels; Willem Hendrik Gispen
Effects of a phorbol ester and cyclosporin A on hippocampal synaptic plasticity in streptozotocin-induced-diabetic rats: reduced sensitivity to phorbol esters.
Neuroscience letters 2003;339(1):45-8.
2003: Mohammad Azhar Kamal; ALAIN ARTOLA; Geert Jan Biessels; Willem Hendrik Gispen; Geert M J Ramakers
Increased spike broadening and slow afterhyperpolarization in CA1 pyramidal cells of streptozotocin-induced diabetic rats.
Neuroscience 2003;118(2):577-83.
2002: Mohammad Azhar Kamal; G Ramesh; N Laxman; P Ramulu; O Srinivas; K Neelima; Anand K Kondapi; Vattipally B Sreenu; Hampapathalu Nagarajaram
Design, synthesis, and evaluation of new noncross-linking pyrrolobenzodiazepine dimers with efficient DNA binding ability and potent antitumor activity.
Journal of medicinal chemistry 2002;45(21):4679-88.
2002: Mohammad Azhar Kamal; Alan Z Segal; Aziz Ulug
Quantitative diffusion-weighted MR imaging in transient ischemic attacks.
AJNR. American journal of neuroradiology 2002;23(9):1533-8.
2002: Mohammad Azhar Kamal; B S Narayan Reddy; G Suresh Kumar Reddy; G Ramesh
Design and synthesis of C-8 linked pyrrolobenzodiazepine-naphthalimide hybrids as anti-tumour agents.
Bioorganic & medicinal chemistry letters 2002;12(15):1933-5.
2002: Mohammad Azhar Kamal; N Laxman; G Ramesh; O Srinivas; P Ramulu
Synthesis of C-8 alkylamino substituted pyrrolo[2,1-c][1,4]benzodiazepines as potential anti-cancer agents.
Bioorganic & medicinal chemistry letters 2002;12(15):1917-9.
2002: Mohammad Azhar Kamal; Mahendra Sandbhor
Efficient chemoenzymatic synthesis of (S)- and (R)-5-(1-aminoethyl)-2-(cyclohexylmethoxy)benzamide: key intermediate for Src-SH2 inhibitor.
Bioorganic & medicinal chemistry letters 2002;12(13):1735-8.
2002: Geert Jan Biessels; Lars van der Heide; Mohammad Azhar Kamal; Ronald L A W Bleys; Willem Hendrik Gispen
Ageing and diabetes: implications for brain function.
European journal of pharmacology 2002;441(1-2):1-14.
2002: Els J M van Dam; Bert Ruiter; Mohammad Azhar Kamal; Geert M J Ramakers; Willem Hendrik Gispen; P N E De Graan
N-methyl-D-aspartate-induced long-term depression is associated with a decrease in postsynaptic protein kinase C substrate phosphorylation in rat hippocampal slices.
Neuroscience letters 2002;320(3):129-32.
2002: Mohammad Azhar Kamal; Maddamsetty V Rao; N Laxman; G Ramesh; G S K Reddy
Recent developments in the design, synthesis and structure-activity relationship studies of pyrrolo[2,1-c][1,4]benzodiazepines as DNA-interactive antitumour antibiotics.
Current medicinal chemistry. Anti-cancer agents 2002;2(2):215-54.
2002: Mohammad Azhar Kamal; Lawrence S B Goldstein
Principles of cargo attachment to cytoplasmic motor proteins.
Current opinion in cell biology 2002;14(1):63-8.
2002: ALAIN ARTOLA; Mohammad Azhar Kamal; Geert M J Ramakers; Fabrizio Gardoni; M Di Luca; Geert Jan Biessels; Flaminio Nicola Cattabeni; Willem Hendrik Gispen
Synaptic plasticity in the diabetic brain: advanced aging?
Progress in brain research 2002;138():305-14.
2001: Josefien C von Frijtag; Mohammad Azhar Kamal; LG Reijmers; Loes H Schrama; Ruud van den Bos; Berry M Spruijt
Chronic imipramine treatment partially reverses the long-term changes of hippocampal synaptic plasticity in socially stressed rats.
Neuroscience letters 2001;309(3):153-6.
2001: Mohammad Azhar Kamal; G Suresh Kumar Reddy; S Raghavan
Solid-phase synthesis of pyrrolo[2,1-c][1,4]benzodiazepine-5,11-diones.
Bioorganic & medicinal chemistry letters 2001;11(3):387-9.
2001: Mohammad Azhar Kamal; K V Ramana; Maddamsetty V Rao
Chemoenzymatic synthesis of pyrrolo[2,1-b]quinazolinones: lipase-catalyzed resolution of vasicinone.
The Journal of organic chemistry 2001;66(3):997-1001.
2001: Geert Jan Biessels; S Smale; Simone Duis; Mohammad Azhar Kamal; Willem Hendrik Gispen
The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats.
Journal of the neurological sciences 2001;182(2):99-106.
2000: A B Bowman; Mohammad Azhar Kamal; B W Ritchings; alastair philp; M McGrail; J G Gindhart; Lawrence S B Goldstein
Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein.
Cell 2000;103(4):583-94.
2000: Mohammad Azhar Kamal; Gorazd B Stokin; Zhaohai Yang; C H Xia; Lawrence S B Goldstein
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I.
Neuron 2000;28(2):449-59.
2000: Mohammad Azhar Kamal; N Laxman; G Ramesh
Facile and efficient one-pot synthesis of 4beta-arylaminopodophyllotoxins: synthesis of DNA topoisomerase II inhibitors (NPF and W-68).
Bioorganic & medicinal chemistry letters 2000;10(18):2059-62.
2000: Mohammad Azhar Kamal; Takashi Okiji; Hideaki Suda
Response of Class II molecule-expressing cells and macrophages to cavity preparation and restoration with 4-META/MMA-TBB resin.
International endodontic journal 2000;33(4):367-73.
2000: Mohammad Azhar Kamal; Geert Jan Biessels; Simone Duis; Willem Hendrik Gispen
Learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: interaction of diabetes and ageing.
Diabetologia 2000;43(4):500-6.
1999: Mohammad Azhar Kamal; Geert M J Ramakers; IJ Urban; P N E De Graan; Willem Hendrik Gispen
Chemical LTD in the CA1 field of the hippocampus from young and mature rats.
The European journal of neuroscience 1999;11(10):3512-6.
1999: A Rahman; Mohammad Azhar Kamal; Elizabeth A Roberts; Lawrence S B Goldstein
Defective kinesin heavy chain behavior in mouse kinesin light chain mutants.
The Journal of cell biology 1999;146(6):1277-88.
1999: Mohammad Azhar Kamal; K Spoelstra; Geert Jan Biessels; IJ Urban; Willem Hendrik Gispen
Effects of changes in glucose concentration on synaptic plasticity in hippocampal slices.
Brain research 1999;824(2):238-42.
1999: Mohammad Azhar Kamal; Geert Jan Biessels; IJ Urban; Willem Hendrik Gispen
Hippocampal synaptic plasticity in streptozotocin-diabetic rats: impairment of long-term potentiation and facilitation of long-term depression.
Neuroscience 1999;90(3):737-45.
1998: Mohammad Azhar Kamal; N L Gayatri; N V Rao
Facile and improved synthesis of 4 beta-aminopodophyllotoxin congeners.
Bioorganic & medicinal chemistry letters 1998;8(21):3097-100.
1998: Geert Jan Biessels; Mohammad Azhar Kamal; IJ Urban; Berry M Spruijt; D W Erkelens; Willem Hendrik Gispen
Water maze learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: effects of insulin treatment.
Brain research 1998;800(1):125-35.
1998: Mohammad Azhar Kamal; Geert Jan Biessels; Willem Hendrik Gispen; IJ Urban
Increasing age reduces expression of long-term depression and dynamic range of transmission plasticity in CA1 field of the rat hippocampus.
Neuroscience 1998;83(3):707-15.
1997: S Webber; R Zheng; Mohammad Azhar Kamal; M Withnall; JA Karlsson
IFN-gamma production from human Th1 cells is controlled by Raf kinase.
International archives of allergy and immunology 1997;113(1-3):275-8.
1996: Geert Jan Biessels; Mohammad Azhar Kamal; Geert M J Ramakers; IJ Urban; Berry M Spruijt; D Willem Erkelens; Willem Hendrik Gispen
Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats.
Diabetes 1996;45(9):1259-66.