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Philip Tsichlis

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Chemicals & Drugs

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Molecular Sequence Data

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Alicia Arranz; Christina Doxaki; Eleftheria Ieronymaki; Eleni D Lagoudaki; Andrew N Margioris; Yeny Martinez de la Torre; Efstathios N Stathopoulos; Philip Tsichlis; Katerina Vaporidi; Maria Venihaki; Eleni Vergadi; Ariadne Androulidaki; Christos Tsatsanis
Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization.
Scott A Ezell; Ailan Guo; Maria Hatziapostolou; Christos Polytarchou; Ioannis Sanidas; George Sourvinos; Teeru Bihani; Michael J Comb; Philip Tsichlis
The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY.
Maria Hatziapostolou; Filippos Kottakis; Georgios Koukos; Athan Kuliopulos; Christos Polytarchou; Oksana Serebrennikova; Philip Tsichlis
Tumor progression locus 2 mediates signal-induced increases in cytoplasmic calcium and cell migration.

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All Publications

2012: Alicia Arranz; Christina Doxaki; Eleftheria Ieronymaki; Eleni D Lagoudaki; Andrew N Margioris; Yeny Martinez de la Torre; Efstathios N Stathopoulos; Philip Tsichlis; Katerina Vaporidi; Maria Venihaki; Eleni Vergadi; Ariadne Androulidaki; Christos Tsatsanis
Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(24):9517-22.
2012: Scott A Ezell; Ailan Guo; Maria Hatziapostolou; Christos Polytarchou; Ioannis Sanidas; George Sourvinos; Teeru Bihani; Michael J Comb; Philip Tsichlis
The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(10):E613-21.
2011: Maria Hatziapostolou; Filippos Kottakis; Georgios Koukos; Athan Kuliopulos; Christos Polytarchou; Oksana Serebrennikova; Philip Tsichlis
Tumor progression locus 2 mediates signal-induced increases in cytoplasmic calcium and cell migration.
Science signaling 2011;4(187):ra55.
2011: Filippos Kottakis; Christos Polytarchou; Ioannis Sanidas; Parthena Foltopoulou; Sotirios C Kampranis; Philip Tsichlis
FGF-2 regulates cell proliferation, migration, and angiogenesis through an NDY1/KDM2B-miR-101-EZH2 pathway.
Molecular cell 2011;43(2):285-98.
2011: Sanda Stankovic; Raffi Gugasyan; Konstantinos Kyparissoudis; Raelene Grumont; Ashish Banerjee; Philip Tsichlis; Steve Gerondakis; Dale I Godfrey
Distinct roles in NKT cell maturation and function for the different transcription factors in the classical NF-κB pathway.
Immunology and cell biology 2011;89(2):294-303.
2010: Dimitrios Iliopoulos; Marianne Lindahl-Allen; Christos Polytarchou; Heather A Hirsch; Philip Tsichlis; Kevin Struhl
Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells.
Molecular cell 2010;39(5):761-72.
2010: Heather A Hirsch; Dimitrios Iliopoulos; Amita Joshi; Yong Zhang; Savina A Jaeger; Martha Bulyk; Philip Tsichlis; X Shirley Liu; Kevin Struhl
A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases.
Cancer cell 2010;17(4):348-61.
2010: Wendy T Watford; Chun-Chi Wang; Christos Tsatsanis; Lisa A Mielke; Aristides G Eliopoulos; Constantine Daskalakis; Nicolas Charles; Sandra Odom; Juan Rivera; John O'Shea; Philip Tsichlis
Ablation of tumor progression locus 2 promotes a type 2 Th cell response in Ovalbumin-immunized mice.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(1):105-13.
2009: Lisa A Mielke; Karen L Elkins; Lai Wei; Robyn Starr; Philip Tsichlis; John J O'Shea; Wendy T Watford
Tumor progression locus 2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1 beta production.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(12):7984-93.
2009: Ariadne Androulidaki; Dimitrios Iliopoulos; Alicia Arranz; Christina Doxaki; Steffen Schworer; Vassiliki Zacharioudaki; Andrew N Margioris; Philip Tsichlis; Christos Tsatsanis
The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs.
Immunity 2009;31(2):220-31.
2009: Alexandros Tzatsos; Raymond Pfau; Sotirios C Kampranis; Philip Tsichlis
Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2641-6.
2009: Miaofen G Hu; Amit Deshpande; Miriam Enos; Daqin Mao; Elisabeth A Hinds; Guo-fu Hu; Rui Chang; Zhuyan Guo; Marei Dose; Changchuin Mao; Philip Tsichlis; Fotini Gounari; Philip W Hinds
A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis.
Cancer research 2009;69(3):810-8.
2009: Dimitrios Iliopoulos; Christos Polytarchou; Maria Hatziapostolou; Filippos Kottakis; Ioanna G Maroulakou; Kevin Struhl; Philip Tsichlis
MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.
Science signaling 2009;2(92):ra62.
2008: Christos Polytarchou; Raymond Pfau; Maria Hatziapostolou; Philip Tsichlis
The JmjC domain histone demethylase Ndy1 regulates redox homeostasis and protects cells from oxidative stress.
Molecular and cellular biology 2008;28(24):7451-64.
2008: Wendy T Watford; Bruce D Hissong; Lydia Durant; Hidehiro Yamane; Linda Muul; Yuka Kanno; Cristina M Tato; Haydeé L Ramos; Alan E Berger; Lisa Mielke; Marko Pesu; Benjamin Solomon; David M Frucht; William Paul; Alan Sher; Dragana Jankovic; Philip Tsichlis; John O'Shea
Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii.
The Journal of experimental medicine 2008;205(12):2803-12.
2008: Ioanna G Maroulakou; William Oemler; Stephen P Naber; Ina Klebba; Charlotte Kuperwasser; Philip Tsichlis
Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.
Journal of cellular physiology 2008;217(2):468-77.
2008: Gary L Wright; Ioanna G Maroulakou; Juanita Eldridge; Tiera L Liby; Vijayalakshmi Sridharan; Philip Tsichlis; Robin C Muise-Helmericks
VEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(9):3264-75.
2008: Maria Hatziapostolou; Christos Polytarchou; Dimitrios Panutsopulos; Lidija Covic; Philip Tsichlis
Proteinase-activated receptor-1-triggered activation of tumor progression locus-2 promotes actin cytoskeleton reorganization and cell migration.
Cancer research 2008;68(6):1851-61.
2008: Christos Tsatsanis; Katerina Vaporidi; Vassiliki Zacharioudaki; Ariadne Androulidaki; Yuri Sykulev; Andrew N Margioris; Philip Tsichlis
Tpl2 and ERK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(8):2987-92.
2008: Raymond Pfau; Alexandros Tzatsos; Sotirios C Kampranis; Oksana B Serebrennikova; Susan E Bear; Philip Tsichlis
Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(6):1907-12.
2007: Osama Odat; Samer Matta; Hadi Khalil; Sotirios C Kampranis; Raymond Pfau; Philip Tsichlis; Antonios M Makris
Old yellow enzymes, highly homologous FMN oxidoreductases with modulating roles in oxidative stress and programmed cell death in yeast.
The Journal of biological chemistry 2007;282(49):36010-23.
2007: M J Robinson; Sören Beinke; A Kouroumalis; Philip Tsichlis; Steven C Ley
Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages.
Molecular and cellular biology 2007;27(21):7355-64.
2007: Gijs J D van Acker; George Perides; Eric R Weiss; Santasabuj Das; Philip Tsichlis; Michael L Steer
Tumor progression locus-2 is a critical regulator of pancreatic and lung inflammation during acute pancreatitis.
The Journal of biological chemistry 2007;282(30):22140-9.
2007: Alexandros Tzatsos; Philip Tsichlis
Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794.
The Journal of biological chemistry 2007;282(25):18069-82.
2007: Terrence M Black; Christine L Andrews; Geoffrey Kilili; Mircea Ivan; Philip Tsichlis; Paul Vouros
Characterization of phosphorylation sites on Tpl2 using IMAC enrichment and a linear ion trap mass spectrometer.
Journal of proteome research 2007;6(6):2269-76.
2007: Changchuin Mao; Esmerina G Tili; Marei Dose; Mariëlle C Haks; Susan E Bear; Ioanna G Maroulakou; Kyoji Horie; George A Gaitanaris; Vincenzo Fidanza; Thomas Ludwig; David L. Wiest; Fotini Gounari; Philip Tsichlis
Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5443-53.
2007: Philip Tsichlis; Maria Hatziapostolou; Philip W Hinds
Timing is everything: regulation of Cdk1 and aneuploidy.
Developmental cell 2007;12(4):477-9.
2007: Ioanna G Maroulakou; William Oemler; Stephen P Naber; Philip Tsichlis
Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice.
Cancer research 2007;67(1):167-77.
2006: Aristides G Eliopoulos; Santasabuj Das; Philip Tsichlis
The tyrosine kinase Syk regulates TPL2 activation signals.
The Journal of biological chemistry 2006;281(3):1371-80.
2006: Michal F Tomczak; Mihaela Gadjeva; Yan Yan Wang; Ketorah Brown; Ioanna G Maroulakou; Philip Tsichlis; Susan E Erdman; James G Fox; Bruce H Horwitz
Defective activation of ERK in macrophages lacking the p50/p105 subunit of NF-kappaB is responsible for elevated expression of IL-12 p40 observed after challenge with Helicobacter hepaticus.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(2):1244-51.
2006: Zhili Shao; Kausik Bhattacharya; Eileen Hsich; Larry Park; Brian Walters; ursula germann; Yow-Ming Wang; John Kyriakis; Ramon Mohanlal; Keisuke Kuida; Mark Namchuk; Francesco Salituro; Yung-mae Yao; Wei-min Hou; Xin Chen; Mark Aronovitz; Philip Tsichlis; Susmita Bhattacharya; Thomas Force; Heiko Kilter
c-Jun N-terminal kinases mediate reactivation of Akt and cardiomyocyte survival after hypoxic injury in vitro and in vivo.
Circulation research 2006;98(1):111-8.
2006: Antonio Cittadini; Maria Gaia Monti; guido iaccarino; Francesca Di Rella; Philip Tsichlis; Angela Di Gianni; Hinrik Strömer; Daniela Sorriento; Cesare Peschle; Bruno Trimarco; Luigi Saccà; Gianluigi Condorelli
Adenoviral gene transfer of Akt enhances myocardial contractility and intracellular calcium handling.
Gene therapy 2006;13(1):8-19.
2005: Katerina Vaporidi; Christos Tsatsanis; Dimitris Georgopoulos; Philip Tsichlis
Effects of hypoxia and hypercapnia on surfactant protein expression proliferation and apoptosis in A549 alveolar epithelial cells.
Life sciences 2005;78(3):284-93.
2005: Keyong Du; Philip Tsichlis
Regulation of the Akt kinase by interacting proteins.
Oncogene 2005;24(50):7401-9.
2005: Joseph R Testa; Philip Tsichlis
AKT signaling in normal and malignant cells.
Oncogene 2005;24(50):7391-3.
2005: Santasabuj Das; Jeonghee Cho; Irina Lambertz; Michelle A Kelliher; Aristides G Eliopoulos; Keyong Du; Philip Tsichlis
Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner.
The Journal of biological chemistry 2005;280(25):23748-57.
2005: Jeonghee Cho; Michael Melnick; Georgios P Solidakis; Philip Tsichlis
Tpl2 (tumor progression locus 2) phosphorylation at Thr290 is induced by lipopolysaccharide via an Ikappa-B Kinase-beta-dependent pathway and is required for Tpl2 activation by external signals.
The Journal of biological chemistry 2005;280(21):20442-8.
2005: Jeonghee Cho; Philip Tsichlis
Phosphorylation at Thr-290 regulates Tpl2 binding to NF-kappaB1/p105 and Tpl2 activation and degradation by lipopolysaccharide.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(7):2350-5.
2004: Pawel Bieganowski; Kara Shilinski; Philip Tsichlis; Charles Brenner
Cdc123 and checkpoint forkhead associated with RING proteins control the cell cycle by controlling eIF2gamma abundance.
The Journal of biological chemistry 2004;279(43):44656-66.
2004: loretta doan; Susan D Porter; Zhijun Duan; Marcella M Flubacher; Diego Montoya; Philip Tsichlis; Marshall Horwitz; C Blake Gilks; H Leighton Grimes
Targeted transcriptional repression of Gfi1 by GFI1 and GFI1B in lymphoid cells.
Nucleic acids research 2004;32(8):2508-19.
2003: Aristides G Eliopoulos; Chun-Chi Wang; Calin D Dumitru; Philip Tsichlis
Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40.
The EMBO journal 2003;22(15):3855-64.
2003: Sylvia Julien Grille; Alfonso Bellacosa; John Upson; Andres J P Klein-Szanto; Frans van Roy; Whaseon L Kwon; Mark Donowitz; Philip Tsichlis; Lionel Larue
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines.
Cancer research 2003;63(9):2172-8.
2003: Carolyn R Hoyal; Abel Gutierrez; Brandon M Young; Sergio D Catz; Jun-Hsiang Lin; Philip Tsichlis; Bernard M Babior
Modulation of p47PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5130-5.
2003: loretta doan; Mary Kate Kitay; Qing Yu; Alfred Singer; Sabine Herblot; Trang Hoang; Susan E Bear; Herbert C Morse; Philip Tsichlis; H Leighton Grimes
Growth factor independence-1B expression leads to defects in T cell activation, IL-7 receptor alpha expression, and T cell lineage commitment.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2356-66.
2002: Dimitris L Kontoyiannis; George Boulougouris; Menelaos Manoloukos; Maria Armaka; Maria Apostolaki; Theresa T Pizarro; Alexey Kotlyarov; Irmgard Forster; Richard Flavell; Matthias Gaestel; Philip Tsichlis; Fabio Cominelli; george kollias
Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease.
The Journal of experimental medicine 2002;196(12):1563-74.
2002: Santasabuj Das; Jun-Hsiang Lin; Joseph Papamatheakis; Yuri Sykulev; Philip Tsichlis
Differential splicing generates Tvl-1/RFXANK isoforms with different functions.
The Journal of biological chemistry 2002;277(47):45172-80.
2002: Gianluigi Condorelli; Carmine Morisco; Michael V G Latronico; Pier Paolo Claudio; Paul Dent; Philip Tsichlis; Gerolama Condorelli; Giacomo Frati; Alessandra Drusco; Carlo M Croce; Claudio Napoli
TNF-alpha signal transduction in rat neonatal cardiac myocytes: definition of pathways generating from the TNF-alpha receptor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(13):1732-7.
2002: Andrea D Basso; David B Solit; Gabriela Chiosis; Banabihari Giri; Philip Tsichlis; Neal Rosen
Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function.
The Journal of biological chemistry 2002;277(42):39858-66.
2002: Giuseppe Viglietto; Maria Letizia Motti; Paola Bruni; Rosa Marina Melillo; Amelia D'Alessio; Daniela Califano; Floriana Vinci; Gennaro Chiappetta; Philip Tsichlis; Alfonso Bellacosa; Alfredo Fusco; Massimo Santoro
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.
Nature medicine 2002;8(10):1136-44.
2002: Aristides G Eliopoulos; Calin D Dumitru; Chun-Chi Wang; Jeonghee Cho; Philip Tsichlis
Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals.
The EMBO journal 2002;21(18):4831-40.
2002: Jinfang Zhu; Liying Guo; Booki Min; Cynthia J Watson; Jane Hu-Li; Howard A Young; Philip Tsichlis; William Paul
Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation.
Immunity 2002;16(5):733-44.
2002: Aristides G Eliopoulos; Clare Davies; Sarah S M Blake; Paul Murray; Sohrab Najafipour; Philip Tsichlis; Lawrence S Young
The oncogenic protein kinase Tpl-2/Cot contributes to Epstein-Barr virus-encoded latent infection membrane protein 1-induced NF-kappaB signaling downstream of TRAF2.
Journal of virology 2002;76(9):4567-79.
2002: Tung O Chan; Ulrich Rodeck; Andrew M Chan; Alec C Kimmelman; Susan E Rittenhouse; George Panayotou; Philip Tsichlis
Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit.
Cancer cell 2002;1(2):181-91.
2001: SE Malstrom; E Tili; D Kappes; JD Ceci; Philip Tsichlis
Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):14967-72.
2001: Whaseon L Kwon; David C Johns; Boyoung Cha; Megan Cavet; J Park; Philip Tsichlis; Mark Donowitz
Constitutively active phosphatidylinositol 3-kinase and AKT are sufficient to stimulate the epithelial Na+/H+ exchanger 3.
The Journal of biological chemistry 2001;276(33):31296-304.
2001: M Sun; G Wang; June E Paciga; Richard I Feldman; Zeng-qiang Yuan; X L Ma; Sue A Shelley; Richard Jove; Philip Tsichlis; Santo V Nicosia; Jin Q Cheng
AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells.
The American journal of pathology 2001;159(2):431-7.
2001: I Mende; SE Malstrom; Philip Tsichlis; Peter K Vogt; Masahiro Aoki
Oncogenic transformation induced by membrane-targeted Akt2 and Akt3.
Oncogene 2001;20(32):4419-23.
2001: Christos Patriotis; Maria Russeva; Jun-Hsiang Lin; S M Srinivasula; D Z Markova; Christos Tsatsanis; AM Makris; E S Alnemri; Philip Tsichlis
Tpl-2 induces apoptosis by promoting the assembly of protein complexes that contain caspase-9, the adapter protein Tvl-1, and procaspase-3.
Journal of cellular physiology 2001;187(2):176-87.
2001: Tung O Chan; Philip Tsichlis
PDK2: a complex tail in one Akt.
Science's STKE : signal transduction knowledge environment 2001;2001(66):pe1.
2000: Calin D Dumitru; JD Ceci; Christos Tsatsanis; Dimitris L Kontoyiannis; K Stamatakis; Jun-Hsiang Lin; Christos Patriotis; N A Jenkins; N G Copeland; george kollias; Philip Tsichlis
TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway.
Cell 2000;103(7):1071-83.
2000: Jean-Luc Poyet; Srinivasa M Srinivasula; Jun-Hsiang Lin; Teresa Fernandes-Alnemri; S Yamaoka; Philip Tsichlis; Emad S Alnemri
Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization.
The Journal of biological chemistry 2000;275(48):37966-77.
2000: Sotirios C Kampranis; R Damianova; M Atallah; Garabet G Toby; G Kondi; Philip Tsichlis; Antonios M Makris
A novel plant glutathione S-transferase/peroxidase suppresses Bax lethality in yeast.
The Journal of biological chemistry 2000;275(38):29207-16.
2000: Gabriella De Vita; Maria Teresa Berlingieri; Roberta Visconti; Maria Domenica Castellone; Giuseppe Viglietto; Gustavo Baldassarre; Mariastella Zannini; A Bellacosa; Philip Tsichlis; Alfredo Fusco; Massimo Santoro
Akt/protein kinase B promotes survival and hormone-independent proliferation of thyroid cells in the absence of dedifferentiating and transforming effects.
Cancer research 2000;60(14):3916-20.
2000: Gabriella De Vita; Rosa Marina Melillo; Francesca Carlomagno; Roberta Visconti; Maria Domenica Castellone; A Bellacosa; Marc Billaud; Alfredo Fusco; Philip Tsichlis; Massimo Santoro
Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival.
Cancer research 2000;60(14):3727-31.
2000: Carmine Morisco; David C Zebrowski; Gianluigi Condorelli; Philip Tsichlis; Stephen F Vatner; Junichi Sadoshima
The Akt-glycogen synthase kinase 3beta pathway regulates transcription of atrial natriuretic factor induced by beta-adrenergic receptor stimulation in cardiac myocytes.
The Journal of biological chemistry 2000;275(19):14466-75.
2000: yuri pekarsky; Anatoliy Koval; Cora Hallas; Roberta Bichi; M Tresini; SE Malstrom; Giandomenico Russo; Philip Tsichlis; Carlo M Croce
Tcl1 enhances Akt kinase activity and mediates its nuclear translocation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3028-33.
1999: M Osada; T Tolkacheva; Weiqun Li; Tung O Chan; Philip Tsichlis; R Saez; Alec C Kimmelman; Andrew M Chan
Differential roles of Akt, Rac, and Ral in R-Ras-mediated cellular transformation, adhesion, and survival.
Molecular and cellular biology 1999;19(9):6333-44.
1999: Srinivasa M Srinivasula; M Ahmad; Jun-Hsiang Lin; Jean-Luc Poyet; Teresa Fernandes-Alnemri; Philip Tsichlis; Emad S Alnemri
CLAP, a novel caspase recruitment domain-containing protein in the tumor necrosis factor receptor pathway, regulates NF-kappaB activation and apoptosis.
The Journal of biological chemistry 1999;274(25):17946-54.
1999: Jun-Hsiang Lin; AM Makris; C McMahon; Susan E Bear; Christos Patriotis; Vinayaka R Prasad; R Brent; Erica A Golemis; Philip Tsichlis
The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1.
The Journal of biological chemistry 1999;274(21):14706-15.
1999: Theodore G Kurowski; Y Lin; Z Luo; Philip Tsichlis; Maria G Buse; Stanley J Heydrick; Neil B Ruderman
Hyperglycemia inhibits insulin activation of Akt/protein kinase B but not phosphatidylinositol 3-kinase in rat skeletal muscle.
Diabetes 1999;48(3):658-63.
1999: Nicholas Grammatikakis; J H Lin; A Grammatikakis; Philip Tsichlis; Brent H Cochran
p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function.
Molecular and cellular biology 1999;19(3):1661-72.
1999: Tung O Chan; Susan E Rittenhouse; Philip Tsichlis
AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation.
Annual review of biochemistry 1999;68():965-1014.
1998: Masahiro Aoki; O Batista; Alfonso Bellacosa; Philip Tsichlis; Peter K Vogt
The akt kinase: molecular determinants of oncogenicity.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14950-5.
1998: Christos Tsatsanis; Christos Patriotis; Philip Tsichlis
Tpl-2 induces IL-2 expression in T-cell lines by triggering multiple signaling pathways that activate NFAT and NF-kappaB.
Oncogene 1998;17(20):2609-18.
1998: Robin C Muise-Helmericks; H Leighton Grimes; Alfonso Bellacosa; SE Malstrom; Philip Tsichlis; Neal Rosen
Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway.
The Journal of biological chemistry 1998;273(45):29864-72.
1998: Alfonso Bellacosa; Tung O Chan; N N Ahmed; K Datta; SE Malstrom; David Stokoe; F McCormick; J Feng; Philip Tsichlis
Akt activation by growth factors is a multiple-step process: the role of the PH domain.
Oncogene 1998;17(3):313-25.
1998: Y Wang; M Falasca; J Schlessinger; SE Malstrom; Philip Tsichlis; Jeffrey Settleman; W Hu; B Lim; Ron Prywes
Activation of the c-fos serum response element by phosphatidyl inositol 3-kinase and rho pathways in HeLa cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(7):513-22.
1998: B Tong; H Leighton Grimes; T Y Yang; Susan E Bear; Z Qin; K Du; Wafik S El-Deiry; Philip Tsichlis
The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation.
Molecular and cellular biology 1998;18(5):2462-73.
1998: Eva M Eves; Wencheng Xiong; A Bellacosa; SG Kennedy; Philip Tsichlis; Marsha Rich Rosner; Nissim Hay
Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line.
Molecular and cellular biology 1998;18(4):2143-52.
1998: Christos Tsatsanis; Christos Patriotis; Susan E Bear; Philip Tsichlis
The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3827-32.
1997: Tomasz Skorski; Alfonso Bellacosa; Margaret Nieborowska-Skorska; M Majewski; Robert Martinez; John K Choi; Rossana Trotta; Pawel Wlodarski; Danilo Perrotti; Tung O Chan; Mariusz A Wasik; Philip Tsichlis; Bruno Calabretta
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.
The EMBO journal 1997;16(20):6151-61.
1997: WG King; M D Mattaliano; Tung O Chan; Philip Tsichlis; Joan S Brugge
Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation.
Molecular and cellular biology 1997;17(8):4406-18.
1997: Hwai Wen Chang; Masahiro Aoki; David A Fruman; KR Auger; Alfonso Bellacosa; Philip Tsichlis; L C Cantley; Thomas M Roberts; Peter K Vogt
Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase.
Science (New York, N.Y.) 1997;276(5320):1848-50.
1997: N N Ahmed; H Leighton Grimes; Alfonso Bellacosa; Tung O Chan; Philip Tsichlis
Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3627-32.
1997: SG Kennedy; Andrew J Wagner; Suzanne D Conzen; Joaquín Jordán; A Bellacosa; Philip Tsichlis; Nissim Hay
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.
Genes & development 1997;11(6):701-13.
1997: JD Ceci; Christos Patriotis; Christos Tsatsanis; AM Makris; R Kovatch; D A Swing; N A Jenkins; Philip Tsichlis; N G Copeland
Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation.
Genes & development 1997;11(6):688-700.
1996: H Leighton Grimes; C Blake Gilks; Tung O Chan; S Porter; Philip Tsichlis
The Gfi-1 protooncoprotein represses Bax expression and inhibits T-cell death.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14569-73.
1996: K Datta; Alfonso Bellacosa; Tung O Chan; Philip Tsichlis
Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells.
The Journal of biological chemistry 1996;271(48):30835-9.
1996: H Leighton Grimes; Tung O Chan; Patrick A Zweidler-McKay; B Tong; Philip Tsichlis
The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal.
Molecular and cellular biology 1996;16(11):6263-72.
1996: Patrick A Zweidler-McKay; H Leighton Grimes; M M Flubacher; Philip Tsichlis
Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor.
Molecular and cellular biology 1996;16(8):4024-34.
1995: T F Franke; S I Yang; Tung O Chan; K Datta; Andrius Kazlauskas; D K Morrison; D R Kaplan; Philip Tsichlis
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase.
Cell 1995;81(5):727-36.
1995: C Blake Gilks; Susan D Porter; C Barker; Philip Tsichlis; Peter W Gout
Prolactin (PRL)-dependent expression of a zinc finger protein-encoding gene, Gfi-1, in Nb2 lymphoma cells: constitutive expression in autonomous sublines.
Endocrinology 1995;136(4):1805-8.
1995: K Datta; T F Franke; Tung O Chan; A Makris; S I Yang; D R Kaplan; D K Morrison; Erica A Golemis; Philip Tsichlis
AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation.
Molecular and cellular biology 1995;15(4):2304-10.
1995: DW Bell; T Taguchi; Nancy A Jenkins; D J Gilbert; Neal G Copeland; C Blake Gilks; Patrick A Zweidler-McKay; H Leighton Grimes; Philip Tsichlis; Joseph R Testa
Chromosomal localization of a gene, GF1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents.
Cytogenetics and cell genetics 1995;70(3-4):263-7.
1994: Christos Patriotis; Philip Tsichlis
The activated Mlvi-4 locus in Moloney murine leukemia virus-induced rat T-cell lymphomas encodes an env/Mlvi-4 fusion protein.
Journal of virology 1994;68(12):7927-32.
1994: M M Flubacher; Susan E Bear; Philip Tsichlis
Replacement of interleukin-2 (IL-2)-generated mitogenic signals by a mink cell focus-forming (MCF) or xenotropic virus-induced IL-9-dependent autocrine loop: implications for MCF virus-induced leukemogenesis.
Journal of virology 1994;68(12):7709-16.
1994: Christos Patriotis; A Makris; Jonathan Chernoff; Philip Tsichlis
Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9755-9.
1994: Alfonso Bellacosa; K Datta; Susan E Bear; Christos Patriotis; P A Lazo; Neal G Copeland; Nancy A Jenkins; Philip Tsichlis
Effects of provirus integration in the Tpl-1/Ets-1 locus in Moloney murine leukemia virus-induced rat T-cell lymphomas: levels of expression, polyadenylation, transcriptional initiation, and differential splicing of the Ets-1 mRNA.
Journal of virology 1994;68(4):2320-30.
1994: T F Franke; K D Tartof; Philip Tsichlis
The SH2-like Akt homology (AH) domain of c-akt is present in multiple copies in the genome of vertebrate and invertebrate eucaryotes. Cloning and characterization of the Drosophila melanogaster c-akt homolog Dakt1.
Oncogene 1994;9(1):141-8.
1993: N N Ahmed; T F Franke; Alfonso Bellacosa; K Datta; Maria Eugenia González; T Taguchi; Joseph R Testa; Philip Tsichlis
The proteins encoded by c-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential.
Oncogene 1993;8(7):1957-63.
1993: A Makris; Christos Patriotis; Susan E Bear; Philip Tsichlis
Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: activation by provirus insertion.
Journal of virology 1993;67(7):4283-9.
1993: C Barker; A Makris; Christos Patriotis; Susan E Bear; Philip Tsichlis
Identification of the gene encoding the mitochondrial elongation factor G in mammals.
Nucleic acids research 1993;21(11):2641-7.
1993: Christos Patriotis; A Makris; Susan E Bear; Philip Tsichlis
Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2251-5.
1993: C Blake Gilks; Susan E Bear; H Leighton Grimes; Philip Tsichlis
Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein.
Molecular and cellular biology 1993;13(3):1759-68.
1993: Alfonso Bellacosa; T F Franke; Maria Eugenia González; K Datta; T Taguchi; J Gardner; Jin Q Cheng; Joseph R Testa; Philip Tsichlis
Structure, expression and chromosomal mapping of c-akt: relationship to v-akt and its implications.
Oncogene 1993;8(3):745-54.
1993: A Makris; Christos Patriotis; Susan E Bear; Philip Tsichlis
Structure of a Moloney murine leukemia virus-virus-like 30 recombinant: implications for transduction of the c-Ha-ras proto-oncogene.
Journal of virology 1993;67(3):1286-91.
1993: Raymond S Yeung; T Taguchi; Christos Patriotis; A Makris; Philip Tsichlis; K K Levan; G Levan; K Tartof; O Hino; Alfred G Knudson; Joseph R Testa
New markers, D16FC1 and Tp12, differentiate between rat chromosomes 16 and 17.
Cytogenetics and cell genetics 1993;62(2-3):149-52.
1993: T Taguchi; Alfonso Bellacosa; J Y Zhou; D J Gilbert; P A Lazo; Neal G Copeland; Nancy A Jenkins; Philip Tsichlis; Joseph R Testa
Chromosomal localization of the Ox-44 (CD53) leukocyte antigen gene in man and rodents.
Cytogenetics and cell genetics 1993;64(3-4):217-21.
1992: C S Barker; Susan E Bear; T Keler; Neal G Copeland; D J Gilbert; Nancy A Jenkins; Raymond S Yeung; Philip Tsichlis
Activation of the prolactin receptor gene by promoter insertion in a Moloney murine leukemia virus-induced rat thymoma.
Journal of virology 1992;66(11):6763-8.
1992: Jin Q Cheng; A K Godwin; Alfonso Bellacosa; T Taguchi; T F Franke; Thomas C Hamilton; Philip Tsichlis; Joseph R Testa
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9267-71.
1991: Alfonso Bellacosa; Joseph R Testa; S P Staal; Philip Tsichlis
A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region.
Science (New York, N.Y.) 1991;254(5029):274-7.
1991: Philip Tsichlis; Susan E Bear
Infection by mink cell focus-forming viruses confers interleukin 2 (IL-2) independence to an IL-2-dependent rat T-cell lymphoma line.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4611-5.
1991: Alfonso Bellacosa; P A Lazo; Susan E Bear; Philip Tsichlis
The rat leukocyte antigen MRC OX-44 is a member of a new family of cell surface proteins which appear to be involved in growth regulation.
Molecular and cellular biology 1991;11(5):2864-72.
1991: Philip Tsichlis; P A Lazo
Virus-host interactions and the pathogenesis of murine and human oncogenic retroviruses.
Current topics in microbiology and immunology 1991;171():95-171.
1990: Antonio Palumbo; Mario Boccadoro; Silvano Battaglio; Paolo Corradini; Philip Tsichlis; K Huebner; Alessandro Pileri; C M Croce
Human homologue of Moloney leukemia virus integration-4 locus (MLVI-4), located 20 kilobases 3' of the myc gene, is rearranged in multiple myelomas.
Cancer research 1990;50(20):6478-82.
1990: P A Lazo; A J Klein-Szanto; Philip Tsichlis
T-cell lymphoma lines derived from rat thymomas induced by Moloney murine leukemia virus: phenotypic diversity and its implications.
Journal of virology 1990;64(8):3948-59.
1990: P A Lazo; Philip Tsichlis
Biology and pathogenesis of retroviruses.
Seminars in oncology 1990;17(3):269-94.
1990: Philip Tsichlis; J S Lee; Susan E Bear; P A Lazo; Christos Patriotis; E Gustafson; Susan A Shinton; Nancy A Jenkins; Neal G Copeland; K Huebner
Activation of multiple genes by provirus integration in the Mlvi-4 locus in T-cell lymphomas induced by Moloney murine leukemia virus.
Journal of virology 1990;64(5):2236-44.
1990: P A Lazo; J S Lee; Philip Tsichlis
Long-distance activation of the Myc protooncogene by provirus insertion in Mlvi-1 or Mlvi-4 in rat T-cell lymphomas.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(1):170-3.
1989: Susan E Bear; Alfonso Bellacosa; P A Lazo; Nancy A Jenkins; Neal G Copeland; Charles Hanson; G Levan; Philip Tsichlis
Provirus insertion in Tpl-1, an Ets-1-related oncogene, is associated with tumor progression in Moloney murine leukemia virus-induced rat thymic lymphomas.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7495-9.
1989: N P Anagnou; A Economou-Pachnis; S J O'Brien; W S Modi; A W Nienhuis; Philip Tsichlis
The human homolog of the Moloney leukemia virus integration 2 locus (MLV12) maps to band p14 of chromosome 5.
Genomics 1989;5(2):354-8.
1989: Philip Tsichlis; B M Shepherd; Susan E Bear
Activation of the Mlvi-1/mis1/pvt-1 locus in Moloney murine leukemia virus-induced T-cell lymphomas.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5487-91.
1989: Alfonso Bellacosa; P A Lazo; Susan E Bear; Susan A Shinton; Philip Tsichlis
Induction of multiple independent T-cell lymphomas in rats inoculated with MOloney murine leukemia virus.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(11):4269-72.
1989: C F Koehne; P A Lazo; K Alves; J S Lee; Philip Tsichlis; P V O'Donnell
The Mlvi-1 locus involved in the induction of rat T-cell lymphomas and the pvt-1/Mis-1 locus are identical.
Journal of virology 1989;63(5):2366-9.
1988: P A Lazo; Philip Tsichlis
Recombination between two integrated proviruses, one of which was inserted near c-myc in a retrovirus-induced rat thymoma: implications for tumor progression.
Journal of virology 1988;62(3):788-94.
1987: J A Bassuk; Philip Tsichlis; S Sorof
Liver fatty acid binding protein is the mitosis-associated polypeptide target of a carcinogen in rat hepatocytes.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(21):7547-51.
1987: P A Lazo; Vinayaka R Prasad; Philip Tsichlis
Splice acceptor site for the env message of Moloney murine leukemia virus.
Journal of virology 1987;61(6):2038-41.
1987: Philip Tsichlis
Oncogenesis by Moloney murine leukemia virus.
Anticancer research 1987;7(2):171-80.
1986: Zvi Wirschubsky; Philip Tsichlis; G Klein; Janos Sumegi
Rearrangement of c-myc, pim-1 and Mlvi-1 and trisomy of chromosome 15 in MCF- and Moloney-MuLV-induced murine T-cell leukemias.
International journal of cancer. Journal international du cancer 1986;38(5):739-45.
1986: A V Furano; C C Somerville; Philip Tsichlis; E D'Ambrosio
Target sites for the transposition of rat long interspersed repeated DNA elements (LINEs) are not random.
Nucleic acids research 1986;14(9):3717-27.
1985: A Economou-Pachnis; Philip Tsichlis
Insertion of an Alu SINE in the human homologue of the Mlvi-2 locus.
Nucleic acids research 1985;13(23):8379-87.
1985: Philip Tsichlis; M A Lohse; Claude Szpirer; J Szpirer; G Levan
Cellular DNA regions involved in the induction of rat thymic lymphomas (Mlvi-1, Mlvi-2, Mlvi-3, and c-myc) represent independent loci as determined by their chromosomal map location in the rat.
Journal of virology 1985;56(3):938-42.
1985: Philip Tsichlis; P G Strauss; M A Lohse
Concerted DNA rearrangements in Moloney murine leukemia virus-induced thymomas: a potential synergistic relationship in oncogenesis.
Journal of virology 1985;56(1):258-67.
1985: P R Shank; P J Schatz; L M Jensen; Philip Tsichlis; John M Coffin; Harriet L Robinson
Sequences in the gag-pol-5'env region of avian leukosis viruses confer the ability to induce osteopetrosis.
Virology 1985;145(1):94-104.
1985: A Economou-Pachnis; M A Lohse; A V Furano; Philip Tsichlis
Insertion of long interspersed repeated elements at the Igh (immunoglobulin heavy chain) and Mlvi-2 (Moloney leukemia virus integration 2) loci of rats.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(9):2857-61.
1985: C A Kozak; P G Strauss; Philip Tsichlis
Genetic mapping of a cellular DNA region involved in induction of thymic lymphomas (Mlvi-1) to mouse chromosome 15.
Molecular and cellular biology 1985;5(4):894-7.
1985: Esther H Chang; P L Morgan; E J Lee; Kathleen F Pirollo; E A White; D H Patrick; Philip Tsichlis
Pathogenicity of retroviruses containing either the normal human c-Ha-ras1 gene or its mutated form derived from the bladder carcinoma EJ/T24 cell line.
Journal of experimental pathology 1985;2(3):177-89.
1984: L A Laimins; Philip Tsichlis; G Khoury
Multiple enhancer domains in the 3' terminus of the Prague strain of Rous sarcoma virus.
Nucleic acids research 1984;12(16):6427-42.
1984: Philip Tsichlis; P G Strauss; C A Kozak
Cellular DNA region involved in induction of thymic lymphomas (Mlvi-2) maps to mouse chromosome 15.
Molecular and cellular biology 1984;4(5):997-1000.
1983: John M Coffin; Philip Tsichlis; K F Conklin; A Senior; H L Robinson
Genomes of endogenous and exogenous avian retroviruses.
Virology 1983;126(1):51-72.
1983: Philip Tsichlis; P G Strauss; L F Hu
A common region for proviral DNA integration in MoMuLV-induced rat thymic lymphomas.
Nature 1983;302(5907):445-9.
1983: Harriet L Robinson; John M Coffin; Philip Tsichlis; P R Shank; P Schatz; L Jensen
Cancer induction by insertional mutagenesis: the role of viral genes in avian leukosis virus induced cancers.
Progress in clinical and biological research 1983;119():37-42.
1983: A M Skalka; Philip Tsichlis; R Malavarca; B Cullen; G Ju
Viral sequences determining the oncogenicity of avian leukosis viruses.
Progress in clinical and biological research 1983;119():105-18.
1982: Philip Tsichlis; L Donehower; G Hager; N Zeller; R Malavarca; S Astrin; A M Skalka
Sequence comparison in the crossover region of an oncogenic avian retrovirus recombinant and its nononcogenic parent: genetic regions that control growth rate and oncogenic potential.
Molecular and cellular biology 1982;2(11):1331-8.
1982: H L Robinson; B M Blais; Philip Tsichlis; John M Coffin
At least two regions of the viral genome determine the oncogenic potential of avian leukosis viruses.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(4):1225-9.
1981: J A Lautenberger; R A Schulz; C F Garon; Philip Tsichlis; TS Papas
Molecular cloning of avian myelocytomatosis virus (MC29) transforming sequences.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(3):1518-22.
1981: John M Coffin; Philip Tsichlis; H L Robinson
Genetics of leukemogenesis by avian leukosis viruses.
Haematology and blood transfusion 1981;26():432-8.
1981: J A Lautenberger; R A Schulz; C F Garon; Philip Tsichlis; Demetri D Spyropoulos; T W Pry; K E Rushlow; TS Papas
The transforming sequences of avian myelocytomatosis virus (MC29).
Journal of supramolecular structure and cellular biochemistry 1981;16(2):193-207.
1980: N Green; H Hiai; J H Elder; Robert S Schwartz; R H Khiroya; C Y Thomas; Philip Tsichlis; John M Coffin
Expression of leukemogenic recombinant viruses associated with a recessive gene in HRS/J mice.
The Journal of experimental medicine 1980;152(2):249-64.
1980: John M Coffin; Philip Tsichlis; C S Barker; S Voynow; H L Robinson
Variation in avian retrovirus genomes.
Annals of the New York Academy of Sciences 1980;354():410-25.
1980: H L Robinson; M N Pearson; D W DeSimone; Philip Tsichlis; John M Coffin
Subgroup-E avian-leukosis-virus-associated disease in chickens.
Cold Spring Harbor symposia on quantitative biology 1980;44 Pt 2,():1133-41.
1980: Philip Tsichlis; John M Coffin
Role of the C region in relative growth rates of endogenous and exogenous avian oncoviruses.
Cold Spring Harbor symposia on quantitative biology 1980;44 Pt 2,():1123-32.
1980: Philip Tsichlis; John M Coffin
Recombinants between endogenous and exogenous avian tumor viruses: role of the C region and other portions of the genome in the control of replication and transformation.
Journal of virology 1980;33(1):238-49.
1980: Philip Tsichlis; K F Conklin; John M Coffin
Mutant and recombinant avian retroviruses with extended host range.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(1):536-40.
1980: Susan E Bear; Philip Tsichlis; Robert S Schwartz
H-2-mediated resistance to an ecotropic type C retrovirus: localization of controlling genes and ontogenic studies of resistance.
Immunogenetics 1980;11(5):451-65.
1979: Philip Tsichlis; John M Coffin
Recombination between the defective component of an acute leukemia virus and Rous associated virus O, an endogenous virus of chickens.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(6):3001-5.
1979: A A Andrianakos; Philip Tsichlis; E G Merikas; A D Efstratopoulos; J T Sharp; S G Marketos; G E Merikas
The effect of glucocorticosteroids on antigen-induced leukocyte migration inhibition.
Materia medica Polona. Polish journal of medicine and pharmacy 1979;11(1):10-4.
1978: S K Datta; Philip Tsichlis; Robert S Schwartz; S K Chattophadhyay; C J Melief
Genetic differences unrelated toH-2 inH-2 congenic mice.
Immunogenetics 1978;7(1):359-65.
1977: A A Andrianakos; Philip Tsichlis; E G Merikas; S G Marketos; J T Sharp; G E Merikas
Cell-mediated immunity in systemic lupus erythematosus.
Clinical and experimental immunology 1977;30(1):89-96.
1977: C Safran; Philip Tsichlis; A Z Bluming; J F Desforges
Diagnostic planning using computer assisted decision-making for patients with Hodgkin's disease.
Cancer 1977;39(6):2426-34.
1977: C Safran; J F Desforges; Philip Tsichlis; A Z Bluming
Decision analysis to evaluate lymphangiography in the management of patients with Hodgkin's disease.
The New England journal of medicine 1977;296(19):1088-92.
1977: J Weens; Philip Tsichlis; Robert S Schwartz; R Khiroya; J Donnelly
Influence of H-2 complex on susceptibility to infection by murine leukemia virus.
Journal of immunology (Baltimore, Md. : 1950) 1977;118(4):1239-43.