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Jeffrey Deschamps

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André A Adams; Paul T Charles; Jeffrey Deschamps; Alfred Hanson; Scott P Veitch; Anne W Kusterbeck
REMUS100 AUV with an integrated microfluidic system for explosives detection.
Dagmar Hajkova Leary; Robert W Li; Jeffrey Deschamps; W Judson Hervey; Anne W Kusterbeck; Gary J Vora
Method development for metaproteomic analyses of marine biofilms.
Terrence L Boos; Kejun Cheng; Jeffrey Deschamps; Elisabeth Greiner; Arthur E Jacobson; Kenner C Rice
Configurational reassignment and improved preparation of the competitive IL-6 receptor antagonist 20R,21R-epoxyresibufogenin-3-formate.

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2013: André A Adams; Paul T Charles; Jeffrey Deschamps; Alfred Hanson; Scott P Veitch; Anne W Kusterbeck
REMUS100 AUV with an integrated microfluidic system for explosives detection.
Analytical and bioanalytical chemistry 2013;405(15):5171-8.
2012: Dagmar Hajkova Leary; Robert W Li; Jeffrey Deschamps; W Judson Hervey; Anne W Kusterbeck; Gary J Vora
Method development for metaproteomic analyses of marine biofilms.
Analytical chemistry 2012;84(9):4006-13.
2012: Terrence L Boos; Kejun Cheng; Jeffrey Deschamps; Elisabeth Greiner; Arthur E Jacobson; Kenner C Rice
Configurational reassignment and improved preparation of the competitive IL-6 receptor antagonist 20R,21R-epoxyresibufogenin-3-formate.
Journal of natural products 2012;75(4):661-8.
2012: Susan Buckhout-White; Philip E Dawson; Jeffrey Deschamps; Ellen R Goldman; Mario Ancona; Juan B Blanco-Canosa; Eunkeu Oh; Michael H Stewart; Igor L Medintz
Multimodal characterization of a linear DNA-based nanostructure.
ACS nano 2012;6(2):1026-43.
2012: Rahul V Edwankar; Ojas A Namjoshi; Jeffrey Deschamps; Chitra R Edwankar; James M Cook
Brønsted acid mediated cyclization of enaminones. Rapid and efficient access to the tetracyclic framework of the Strychnos alkaloids.
Journal of natural products 2012;75(2):181-8.
2012: Kelly Boeneman; James B Delehanty; Jeffrey Deschamps; Michael H Stewart; Kimihiro Susumu; Igor L Medintz
Quantum dots and fluorescent protein FRET-based biosensors.
Advances in experimental medicine and biology 2012;733():63-74.
2011: Avital Steinberg; Damon A Parrish; Jeffrey Deschamps; Mark Froimowitz; Robert Glaser
Solution- and solid-state conformations of C(α)-alkyl analogues of methylphenidate (Ritalin) salts: avoidance of gauche(+)gauche(-) interactions.
The Journal of organic chemistry 2011;76(22):9239-45.
2011: André A Adams; Paul T Charles; Jeffrey Deschamps; Anne W Kusterbeck
Demonstration of submersible high-throughput microfluidic immunosensors for underwater explosives detection.
Analytical chemistry 2011;83(22):8411-9.
2011: Feng Li; Richard B Rothman; Kejun Cheng; Jason A Deck; Christina M Dersch; Jeffrey Deschamps; John E Folk; Arthur E Jacobson; Muneaki Kurimura; Kenner C Rice
Probes for narcotic receptor mediated phenomena. 43. Synthesis of the ortho-a and para-a, and improved synthesis and optical resolution of the ortho-b and para-b oxide-bridged phenylmorphans: compounds with moderate to low opioid-receptor affinity.
Bioorganic & medicinal chemistry 2011;19(14):4330-7.
2011: Ojas A Namjoshi; Angelica Gryboski; German O Fonseca; Michael L Van Linn; Zhi-jian Wang; Jeffrey Deschamps; James M Cook
Development of a two-step route to 3-PBC and βCCt, two agents active against alcohol self-administration in rodent and primate models.
The Journal of organic chemistry 2011;76(11):4721-7.
2011: Jin-Hee Kim; Jeffrey Deschamps; Richard B Rothman; Christina M Dersch; John E Folk; Kejun Cheng; Arthur E Jacobson; Kenner C Rice
Probes for narcotic receptor mediated phenomena. Part 42: synthesis and in vitro pharmacological characterization of the N-methyl and N-phenethyl analogues of the racemic ortho-c and para-c oxide-bridged phenylmorphans.
Bioorganic & medicinal chemistry 2011;19(11):3434-43.
2011: Kim E Sapsford; Jessica Granek; Jeffrey Deschamps; Kelly Boeneman; Juan Bautista Blanco-Canosa; Philip E Dawson; Kimihiro Susumu; Michael H Stewart; Igor L Medintz
Monitoring botulinum neurotoxin a activity with peptide-functionalized quantum dot resonance energy transfer sensors.
ACS nano 2011;5(4):2687-99.
2011: Brandy J Johnson; Anthony P Malanoski; Brian J Melde; Mansoor Nasir; Nicole E Anderson; Paul T Charles; Jeffrey Deschamps
Porphyrin-embedded silicate materials for detection of hydrocarbon solvents.
Sensors (Basel, Switzerland) 2011;11(1):886-904.
2010: Kelly Boeneman; Jeffrey Deschamps; Susan Buckhout-White; Duane E Prasuhn; Juan B Blanco-Canosa; Philip E Dawson; Michael H Stewart; Kimihiro Susumu; Ellen R Goldman; Mario Ancona; Igor L Medintz
Quantum dot DNA bioconjugates: attachment chemistry strongly influences the resulting composite architecture.
ACS nano 2010;4(12):7253-66.
2010: Haiying Sun; Jianfeng Lu; Liu Liu; Han Yi; Su Qiu; Chao-Yie Yang; Jeffrey Deschamps; Shaomeng Wang
Nonpeptidic and potent small-molecule inhibitors of cIAP-1/2 and XIAP proteins.
Journal of medicinal chemistry 2010;53(17):6361-7.
2010: Christopher M Spillmann; John H Konnert; James M Adams; Jeffrey Deschamps; Jawad naciri; Banahalli R Ratna
Strain analysis of a chiral smectic-A elastomer.
Physical review. E, Statistical, nonlinear, and soft matter physics 2010;82(3 Pt 1):031705.
2010: Duane E Prasuhn; Jeffrey Deschamps; Kimihiro Susumu; Michael H Stewart; Kelly Boeneman; Juan B Blanco-Canosa; Philip E Dawson; Igor L Medintz
Polyvalent display and packing of peptides and proteins on semiconductor quantum dots: predicted versus experimental results.
Small (Weinheim an der Bergstrasse, Germany) 2010;6(4):555-64.
2010: Paul T Charles; Jeffrey Deschamps; Peter B Howell; Andre A Adams; Scott A Trammell; Anne W Kusterbeck
Fluorescence-based sensing of 2,4,6-trinitrotoluene (TNT) using a multi-channeled poly(methyl methacrylate) (PMMA) microimmunosensor.
Sensors (Basel, Switzerland) 2010;10(1):876-89.
2010: Brandy J Johnson; Iwona A Leska; Anthony P Malanoski; Brian J Melde; Damon A Parrish; Cassandra Thomas; Paul T Charles; Jeffrey Deschamps
Fluorescent silicate materials for the detection of paraoxon.
Sensors (Basel, Switzerland) 2010;10(3):2315-31.
2010: Malliga R Iyer; Yong-Sok Lee; Jeffrey Deschamps; Richard B Rothman; Christina M Dersch; Arthur E Jacobson; Kenner C Rice
Probes for narcotic receptor mediated phenomena. 40. N-substituted cis-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ols.
Bioorganic & medicinal chemistry 2010;18(1):91-9.
2009: Yi Zhang; Yong-Sok Lee; Richard B Rothman; Christina M Dersch; Jeffrey Deschamps; Arthur E Jacobson; Kenner C Rice
Probes for narcotic receptor mediated phenomena. 39. Enantiomeric N-substituted benzofuro[2,3-c]pyridin-6-ols: synthesis and topological relationship to oxide-bridged phenylmorphans.
Journal of medicinal chemistry 2009;52(23):7570-9.
2009: Pamela L Russ; Maria J Gonzalez-Moa; B Christie Vu; Dina M Sigano; James A Kelley; Christopher C Lai; Jeffrey Deschamps; Stephen H Hughes; Victor E Marquez
North- and south-bicyclo[3.1.0]hexene nucleosides: the effect of ring planarity on anti-HIV activity.
ChemMedChem 2009;4(8):1354-63.
2009: Igor L Medintz; Dorothy Farrell; Kimihiro Susumu; Scott A Trammell; Jeffrey Deschamps; Florence Brunel; Philip E Dawson; Hedi Mattoussi
Multiplex charge-transfer interactions between quantum dots and peptide-bridged ruthenium complexes.
Analytical chemistry 2009;81(12):4831-9.
2009: Santosh S Kulkarni; Mu-Fa Zou; Jianjing Cao; Jeffrey Deschamps; Alice L Rodriguez; P Jeffrey Conn; Amy Hauck Newman
Structure-activity relationships comparing N-(6-methylpyridin-yl)-substituted aryl amides to 2-methyl-6-(substituted-arylethynyl)pyridines or 2-methyl-4-(substituted-arylethynyl)thiazoles as novel metabotropic glutamate receptor subtype 5 antagonists.
Journal of medicinal chemistry 2009;52(11):3563-75.
2009: Amy Hauck Newman; Peter Grundt; George Cyriac; Jeffrey Deschamps; Michelle Taylor; Rakesh Kumar; David Ho; Robert R Luedtke
N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists.
Journal of medicinal chemistry 2009;52(8):2559-70.
2009: Hephzibah J Kumpaty; Michael L Van Linn; M Shahjahan Kabir; F Holger Försterling; Jeffrey Deschamps; James M Cook
Study of the cis to trans isomerization of 1-phenyl-2,3-disubstituted tetrahydro-beta-carbolines at C(1). Evidence for the carbocation-mediated mechanism.
The Journal of organic chemistry 2009;74(7):2771-9.
2009: Kelly Boeneman; Bing C Mei; Allison M Dennis; Gang Bao; Jeffrey Deschamps; Hedi Mattoussi; Igor L Medintz
Sensing caspase 3 activity with quantum dot-fluorescent protein assemblies.
Journal of the American Chemical Society 2009;131(11):3828-9.
2008: Muneaki Kurimura; Hehua Liu; Agnieszka Sulima; Akihiro Hashimoto; Anna K Przybyl; Etsuo Ohshima; Shinichi Kodato; Jeffrey Deschamps; Christina M Dersch; Richard B Rothman; Yong Sok Lee; Arthur E Jacobson; Kenner C Rice
Probes for narcotic receptor mediated phenomena. 37. Synthesis and opioid binding affinity of the final pair of oxide-bridged phenylmorphans, the ortho- and para-b-isomers and their N-phenethyl analogues, and the synthesis of the N-phenethyl analogues of the ortho- and para-d-isomers.
Journal of medicinal chemistry 2008;51(24):7866-81.
2008: Noel M Paul; Michelle Taylor; Rakesh Kumar; Jeffrey Deschamps; Robert R Luedtke; Amy Hauck Newman
Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol.
Journal of medicinal chemistry 2008;51(19):6095-109.
2008: Dongmei Han; F Holger Försterling; Xiaoyan Li; Jeffrey Deschamps; Damon Parrish; Hui Cao; Sundari Rallapalli; Terry Clayton; Yun Teng; Samarpan Majumder; Subramaniam Sankar; Bryan L Roth; Werner Sieghart; Roman Furtmuller; James K Rowlett; Michael Weed; James M Cook
A study of the structure-activity relationship of GABA(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis.
Bioorganic & medicinal chemistry 2008;16(19):8853-62.
2008: Dehui Duan; Dina M Sigano; James A Kelley; Christopher C Lai; Nancy E Lewin; Noemi Kedei; Megan L Peach; Jeewoo Lee; Thushara P Abeyweera; Susan A Rotenberg; Hee Kim; Young Ho Kim; Saïd El Kazzouli; Jae-Uk Chung; Howard A Young; Matthew R Young; Alyson Baker; Nancy H Colburn; Adriana Haimovitz-Friedman; Jean-Philip Truman; Damon Parrish; Jeffrey Deschamps; Nicholas A Perry; Robert J Surawski; Peter M Blumberg; Victor E Marquez
Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities.
Journal of medicinal chemistry 2008;51(17):5198-220.
2008: Josef Zezula; Lisa Singer; Anna K Przybył; Akihiro Hashimoto; Christina M Dersch; Richard B Rothman; Jeffrey Deschamps; Yong-Sok Lee; Arthur E Jacobson; Kenner C Rice
Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans.
Organic & biomolecular chemistry 2008;6(16):2868-83.
2008: Jie Yang; Xiangyu Z Wearing; Philip W Le Quesne; Jeffrey Deschamps; James M Cook
Enantiospecific synthesis of (+)-alstonisine via a stereospecific osmylation process.
Journal of natural products 2008;71(8):1431-40.
2008: Carlos A Valdez; Joseph E Saavedra; Brett M Showalter; Keith M Davies; Thomas C Wilde; Michael L Citro; Joseph J Barchi; Jeffrey Deschamps; Damon Parrish; Stefan El-Gayar; Ulrike Schleicher; Christian Bogdan; Larry K Keefer
Hydrolytic reactivity trends among potential prodrugs of the O2-glycosylated diazeniumdiolate family. Targeting nitric oxide to macrophages for antileishmanial activity.
Journal of medicinal chemistry 2008;51(13):3961-70.
2008: Stanislav Engel; Amanda P Skoumbourdis; John Childress; Susanne Neumann; Jeffrey Deschamps; Craig J Thomas; Anny-Odile Colson; Stefano Costanzi; Marvin C Gershengorn
A virtual screen for diverse ligands: discovery of selective G protein-coupled receptor antagonists.
Journal of the American Chemical Society 2008;130(15):5115-23.
2008: Emilie D Smith; N Ariane Vinson; Desong Zhong; Bertold D Berrang; Jennifer L Catanzaro; James B Thomas; Hernán A Navarro; Brian P Gilmour; Jeffrey Deschamps; Frank carroll
A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay.
Bioorganic & medicinal chemistry 2008;16(2):822-9.
2007: Huifang Wu; Trudy A Smith; Hongyan Huang; Jia Bei Wang; Jeffrey Deschamps; Andrew Coop
Functionalization of the 6,14-bridge of the orvinols. Part 3: preparation and pharmacological evaluation of 18- and 19-hydroxyl substituted orvinols.
Bioorganic & medicinal chemistry letters 2007;17(17):4829-31.
2007: Anne-Cécile Hiebel; Yong-Sok Lee; Edward J Bilsky; Denise Giuvelis; Jeffrey Deschamps; Damon Parrish; Mario D Aceto; Everette L May; Louis S Harris; Andrew Coop; Christina M Dersch; John S Partilla; Richard B Rothman; Kejun Cheng; Arthur E Jacobson; Kenner C Rice
Probes for narcotic receptor mediated phenomena. 34. Synthesis and structure-activity relationships of a potent mu-agonist delta-antagonist and an exceedingly potent antinociceptive in the enantiomeric C9-substituted 5-(3-hydroxyphenyl)-N-phenylethylmorphan series.
Journal of medicinal chemistry 2007;50(16):3765-76.
2007: Denise S Simpson; Peter L Katavic; Anthony Lozama; Wayne W Harding; Damon Parrish; Jeffrey Deschamps; Christina M Dersch; John S Partilla; Richard B Rothman; Hernan Navarro; Thomas E Prisinzano
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: preparation and opioid receptor activity of salvinicin analogues.
Journal of medicinal chemistry 2007;50(15):3596-603.
2007: Maria J Comin; Riad Agbaria; Tsipi Ben-Kasus; Mahmoud Huleihel; Chenzhong Liao; Guangyu Sun; Marc C Nicklaus; Jeffrey Deschamps; Damon Parrish; Victor E Marquez
Sculpting the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve recognition by herpes thymidine kinase.
Journal of the American Chemical Society 2007;129(19):6216-22.
2007: Mark Froimowitz; Yonghong Gu; Les A Dakin; Pamela M Nagafuji; Charles J Kelley; Damon Parrish; Jeffrey Deschamps; Aaron Janowsky
Slow-onset, long-duration, alkyl analogues of methylphenidate with enhanced selectivity for the dopamine transporter.
Journal of medicinal chemistry 2007;50(2):219-32.
2007: Duy-Phong Pham-Huu; Jeffrey Deschamps; Shanghao Liu; Bertha K Madras; Peter C Meltzer
Synthesis of 8-thiabicyclo[3.2.1]octanes and their binding affinity for the dopamine and serotonin transporters.
Bioorganic & medicinal chemistry 2007;15(2):1067-82.
2007: Dongmei Han; F Holger Försterling; Jeffrey Deschamps; Damon Parrish; Xiaoxiang Liu; Wenyuan Yin; Shengming Huang; James M Cook
Conformational analysis of the cis- and trans-adducts of the Pictet - Spengler reaction. Evidence for the structural basis for the C(1) - N(2) scission process in the cis- to trans-isomerization.
Journal of natural products 2007;70(1):75-82.
2006: Frank carroll; Bruce E Blough; Xiaodong Huang; Zhe Nie; Wayne Mascarella; Jeffrey Deschamps; Hernán A Navarro
Synthesis and monoamine transporter binding properties of 2,3-cyclo analogues of 3beta-(4'-aminophenyl)-2beta-tropanemethanol.
Journal of medicinal chemistry 2006;49(15):4589-94.
2006: Shijun Zhang; Fernando Fernandez; Stuart T Hazeldine; Jeffrey Deschamps; Juan Zhen; Maarten E A Reith; Aloke Dutta
Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters.
Journal of medicinal chemistry 2006;49(14):4239-47.
2006: Igor L Medintz; Aaron R Clapp; Florence Brunel; Theresa Tiefenbrunn; H Tetsuo Uyeda; Eddie L Chang; Jeffrey Deschamps; Philip E Dawson; Hedi Mattoussi
Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates.
Nature materials 2006;5(7):581-9.
2006: Kevin Tidgewell; Wayne W Harding; Anthony Lozama; Howard Cobb; Kushal Shah; Pavitra Kannan; Christina M Dersch; Damon Parrish; Jeffrey Deschamps; Richard B Rothman; Thomas E Prisinzano
Synthesis of salvinorin A analogues as opioid receptor probes.
Journal of natural products 2006;69(6):914-8.
2006: Frank carroll; Xingding Hu; Hernán A Navarro; Jeffrey Deschamps; Galya R Abdrakhmanova; M Imad Damaj; Billy R Martin
Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes.
Journal of medicinal chemistry 2006;49(11):3244-50.
2006: Krzysztof Krajewski; Yijun Zhang; Damon Parrish; Jeffrey Deschamps; Peter P Roller; Vinay Pathak
New HIV-1 reverse transcriptase inhibitors based on a tricyclic benzothiophene scaffold: synthesis, resolution, and inhibitory activity.
Bioorganic & medicinal chemistry letters 2006;16(11):3034-8.
2006: Peter C Meltzer; David Butler; Jeffrey Deschamps; Bertha K Madras
1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.
Journal of medicinal chemistry 2006;49(4):1420-32.
2006: Maria J Comin; Damon Parrish; Jeffrey Deschamps; Victor E Marquez
Synthesis of bicyclo[3.1.0]hexanes functionalized at the tip of the cyclopropane ring. Application to the synthesis of carbocyclic nucleosides.
Organic letters 2006;8(4):705-8.
2006: Joseph E Saavedra; Aloka Srinivasan; Gregory S Buzard; Keith M Davies; David J Waterhouse; Keiko Inami; Thomas C Wilde; Michael L Citro; Matthew Cuellar; Jeffrey Deschamps; Damon Parrish; Paul J Shami; Victoria J Findlay; Danyelle M Townsend; Kenneth D Tew; Shivendra Singh; Lee Jia; Xinhua Ji; Larry K Keefer
PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.
Journal of medicinal chemistry 2006;49(3):1157-64.
2006: Igor L Medintz; Jeffrey Deschamps
Maltose-binding protein: a versatile platform for prototyping biosensing.
Current opinion in biotechnology 2006;17(1):17-27.
2005: Frank carroll; Sachin Chaudhari; James B Thomas; Wayne Mascarella; Kenneth M Gigstad; Jeffrey Deschamps; Hernán A Navarro
N-substituted cis-4a-(3-hydroxyphenyl)-8a-methyloctahydroisoquinolines are opioid receptor pure antagonists.
Journal of medicinal chemistry 2005;48(26):8182-93.
2005: Hongfeng Deng; Andrew N Gifford; Alexander M Zvonok; Guangjian Cui; Xiuyan Li; Pusheng Fan; Jeffrey Deschamps; Judith L Flippen-Anderson; S John Gatley; Alexandros Makriyannis
Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor.
Journal of medicinal chemistry 2005;48(20):6386-92.
2005: Agnieszka Sulima; Thomas E Prisinzano; Thomas Spande; Jeffrey Deschamps; Noel Whittaker; Zeev Hochberg; Arthur E Jacobson; Kenner C Rice
A concise method for the preparation of deuterium-labeled cortisone: synthesis of [6,7-2H]cortisone.
Steroids 2005;70(11):763-9.
2005: Ke Ding; Yipin Lu; Zaneta Nikolovska-Coleska; Su Qiu; Yousong Ding; Wei Gao; Jeanne A Stuckey; Krzysztof Krajewski; Peter P Roller; York Tomita; Damon Parrish; Jeffrey Deschamps; Shaomeng Wang
Structure-based design of potent non-peptide MDM2 inhibitors.
Journal of the American Chemical Society 2005;127(29):10130-1.
2005: Amy Szuchmacher Blum; Tong Ren; Damon A Parish; Scott A Trammell; Martin H Moore; James G Kushmerick; Guo-Lin Xu; Jeffrey Deschamps; Steven K Pollack; Ranganathan Shashidhar
Ru2(ap)4(sigma-oligo(phenyleneethynyl)) molecular wires: synthesis and electronic characterization.
Journal of the American Chemical Society 2005;127(28):10010-1.
2005: Dai Lu; Zhaoxing Meng; Ganesh A Thakur; Pusheng Fan; John Steed; Cindy L Tartal; Dow P Hurst; Patricia H Reggio; Jeffrey Deschamps; Damon Parrish; Clifford George; Torbjörn U C Järbe; Richard J Lamb; Alexandros Makriyannis
Adamantyl cannabinoids: a novel class of cannabinergic ligands.
Journal of medicinal chemistry 2005;48(14):4576-85.
2005: Wayne W Harding; Kevin Tidgewell; Matthew Schmidt; Kushal Shah; Christina M Dersch; John Snyder; Damon Parrish; Jeffrey Deschamps; Richard B Rothman; Thomas E Prisinzano
Salvinicins A and B, new neoclerodane diterpenes from Salvia divinorum.
Organic letters 2005;7(14):3017-20.
2005: Huifang Wu; Linn N Thatcher; Denzil Bernard; Damon Parrish; Jeffrey Deschamps; Kenner C Rice; Alexander D. Mackerell; Andrew Coop
Position of coordination of the lithium ion determines the regioselectivity of demethylations of 3,4-dimethoxymorphinans with L-selectride.
Organic letters 2005;7(13):2531-4.
2005: Mark Froimowitz; Yonghong Gu; Les A Dakin; Charles J Kelley; Damon Parrish; Jeffrey Deschamps
Vinylogous amide analogs of methylphenidate.
Bioorganic & medicinal chemistry letters 2005;15(12):3044-7.
2005: P V V Srirama Sarma; Dongmei Han; Jeffrey Deschamps; James M Cook
Confirmation of the structure of (3S)-3-hydroxyquinine: synthesis and X-ray crystal structure of its 9-aceto analogue.
Journal of natural products 2005;68(6):942-4.
2005: Marco Crisma; Jeffrey Deschamps; C George; Judith L Flippen-Anderson; Bernard Kaptein; Quirinus B Broxterman; Alessandro Moretto; Simona Oancea; Micha Jost; Fernando Formaggio; Claudio Toniolo
A topographically and conformationally constrained, spin-labeled, alpha-amino acid: crystallographic characterization in peptides.
The journal of peptide research : official journal of the American Peptide Society 2005;65(6):564-79.
2005: Ellen R Goldman; Igor L Medintz; Jessica L Whitley; Andrew Hayhurst; Aaron R Clapp; H Tetsuo Uyeda; Jeffrey Deschamps; Michael E Lassman; Hedi Mattoussi
A hybrid quantum dot-antibody fragment fluorescence resonance energy transfer-based TNT sensor.
Journal of the American Chemical Society 2005;127(18):6744-51.
2005: Ke Ding; Jianyong Chen; Min Ji; Xihan Wu; Judith Varady; Chao-Yie Yang; Yipin Lu; Jeffrey Deschamps; Beth Levant; Shaomeng Wang
Enantiomerically pure hexahydropyrazinoquinolines as potent and selective dopamine 3 subtype receptor ligands.
Journal of medicinal chemistry 2005;48(9):3171-81.
2005: Yan-Ni Wang; D Scott Bohle; Challice L Bonifant; Gwendolyn N Chmurny; Jack R Collins; Keith M Davies; Jeffrey Deschamps; Judith L Flippen-Anderson; Larry K Keefer; John R Klose; Joseph E Saavedra; David J Waterhouse; Joseph Ivanic
Chemistry of the diazeniumdiolates: Z right harpoon over left harpoon E isomerism.
Journal of the American Chemical Society 2005;127(15):5388-95.
2005: Scott P Runyon; Jason P Burgess; Philip Abraham; Kathryn I Keverline-Frantz; Judith L Flippen-Anderson; Jeffrey Deschamps; Anita H Lewin; Hernán A Navarro; John W Boja; Michael J Kuhar; Frank carroll
Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product.
Bioorganic & medicinal chemistry 2005;13(7):2439-49.
2005: Huifang Wu; Denzil Bernard; Weibin Chen; Gary Strahan; Jeffrey Deschamps; Damon Parrish; John W Lewis; Alexander D. Mackerell; Andrew Coop
Functionalization of the 6,14-bridge of the orvinols. 2. Preparation of 18- and 19-hydroxyl-substituted thevinols and their treatment with benzyl bromide.
The Journal of organic chemistry 2005;70(5):1907-10.
2005: Weiming Luo; Qian-Sheng Yu; Ming Zhan; Damon Parrish; Jeffrey Deschamps; Santosh S Kulkarni; Harold W Holloway; George M Alley; Debomoy K Lahiri; Arnold Brossi; Nigel H Greig
Novel anticholinesterases based on the molecular skeletons of furobenzofuran and methanobenzodioxepine.
Journal of medicinal chemistry 2005;48(4):986-94.
2005: Hui Cao; Scott G Van Ornum; Jeffrey Deschamps; Judith L Flippen-Anderson; Frank Laib; James M Cook
Synthesis of dicyclopenta[a,e]pentalenes via a molybdenum carbonyl mediated tandem allenic Pauson-Khand reaction and the X-ray crystal structure of a planar dicyclopenta[a,e]pentalene.
Journal of the American Chemical Society 2005;127(3):933-43.
2005: Igor L Medintz; Ellen R Goldman; Michael E Lassman; Andrew Hayhurst; Anne W Kusterbeck; Jeffrey Deschamps
Self-assembled TNT biosensor based on modular multifunctional surface-tethered components.
Analytical chemistry 2005;77(2):365-72.
2005: Jeffrey Deschamps
The role of crystallography in drug design.
The AAPS journal 2005;7(4):E813-9.
2004: Joseph E Saavedra; D Scott Bohle; Kamilah N Smith; Clifford George; Jeffrey Deschamps; Damon Parrish; Joseph Ivanic; Yan-Ni Wang; Michael L Citro; Larry K Keefer
Chemistry of the diazeniumdiolates. O- versus N-alkylation of the RNH[N(O)NO](-) ion.
Journal of the American Chemical Society 2004;126(40):12880-7.
2004: Rohit Kolhatkar; charlie cook; Sujit K Ghorai; Jeffrey Deschamps; Patrick M Beardsley; Maarten E A Reith; Aloke Dutta
Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters.
Journal of medicinal chemistry 2004;47(21):5101-13.
2004: Kim E Sapsford; Igor L Medintz; Joel P Golden; Jeffrey Deschamps; H Tetsuo Uyeda; Hedi Mattoussi
Surface-immobilized self-assembled protein-based quantum dot nanoassemblies.
Langmuir : the ACS journal of surfaces and colloids 2004;20(18):7720-8.
2004: Akihiro Hashimoto; Anna K Przybyl; Joannes T M Linders; Shinichi Kodato; Xinrong Tian; Jeffrey Deschamps; Clifford George; Judith L Flippen-Anderson; Arthur E Jacobson; Kenner C Rice
Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans.
The Journal of organic chemistry 2004;69(16):5322-7.
2004: Igor L Medintz; John H Konnert; Aaron R Clapp; I Stanish; M E Twigg; Hedi Mattoussi; J Matthew Mauro; Jeffrey Deschamps
A fluorescence resonance energy transfer-derived structure of a quantum dot-protein bioconjugate nanoassembly.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9612-7.
2004: Nurulain Zaveri; Faming Jiang; Cris M Olsen; Jeffrey Deschamps; Damon Parrish; Willma E Polgar; Lawrence Toll
A novel series of piperidin-4-yl-1,3-dihydroindol-2-ones as agonist and antagonist ligands at the nociceptin receptor.
Journal of medicinal chemistry 2004;47(12):2973-6.
2004: Dongmei Han; F Holger Försterling; Xiaoyan Li; Jeffrey Deschamps; Hui Cao; James M Cook
Determination of the stable conformation of GABA(A)-benzodiazepine receptor bivalent ligands by low temperature NMR and X-ray analysis.
Bioorganic & medicinal chemistry letters 2004;14(6):1465-9.
2004: Shinichi Kodato; Joannes T M Linders; Xiao-Hui Gu; Koichiro Yamada; Judith L Flippen-Anderson; Jeffrey Deschamps; Arthur E Jacobson; Kenner C Rice
Synthesis of rac-(1R,4aR,9aR)-2-methyl-1,3,4,9a-tetrahydro-2H-1,4a-propanobenzofuro[2,3-c]pyridin-6-ol. An unusual double rearrangement leading to the ortho- and para-f oxide-bridged phenylmorphan isomers.
Organic & biomolecular chemistry 2004;2(3):330-6.
2004: Paul T Charles; Lisa C Shriver-Lake; Stephen C Francesconi; Albert M Churilla; Jermain G Rangasammy; Charles H Patterson; Jeffrey Deschamps; Anne W Kusterbeck
Characterization and performance evaluation of in vivo and in vitro produced monoclonal anti-TNT antibodies for the detection of TNT.
Journal of immunological methods 2004;284(1-2):15-26.
2003: Xiaoyan Li; Hui Cao; Chunchun Zhang; Roman Furtmueller; Karoline Fuchs; Sigismund Huck; Werner Sieghart; Jeffrey Deschamps; James M Cook
Synthesis, in vitro affinity, and efficacy of a bis 8-ethynyl-4H-imidazo[1,5a]- [1,4]benzodiazepine analogue, the first bivalent alpha5 subtype selective BzR/GABA(A) antagonist.
Journal of medicinal chemistry 2003;46(26):5567-70.
2003: Jianming Yu; Tao Wang; Xiaoxiang Liu; Jeffrey Deschamps; Judith L Flippen-Anderson; Xuebin Liao; James M Cook
General approach for the synthesis of sarpagine indole alkaloids. Enantiospecific total synthesis of (+)-vellosimine, (+)-normacusine B, (-)-alkaloid Q3, (-)-panarine, (+)-Na-methylvellosimine, and (+)-Na-methyl-16-epipericyclivine.
The Journal of organic chemistry 2003;68(20):7565-81.
2003: Weibin Chen; Huifang Wu; Denzil Bernard; Matthew D Metcalf; Jeffrey Deschamps; Judith L Flippen-Anderson; Alexander D. Mackerell; Andrew Coop
Rearrangement of 5-trimethylsilylthebaine on treatment with L-selectride: an efficient synthesis of (+)-bractazonine.
The Journal of organic chemistry 2003;68(5):1929-32.
2002: Sharon D Bryant; Clifford George; Judith L Flippen-Anderson; Jeffrey Deschamps; Severo Salvadori; Gianfranco Balboni; Remo Guerrini; Lawrence H Lazarus
Crystal structures of dipeptides containing the Dmt-Tic pharmacophore.
Journal of medicinal chemistry 2002;45(25):5506-13.
2002: Jeffrey Deschamps; Clifford George; Judith L Flippen-Anderson
(1R)-2-[(3R,4S)-3-Methyl-4-(N-phenyl-N-propionylamino)piperidin-1-yl]-1-phenylethyl p-bromobenzoate and N-[(3R,4S)-1-[(2S)-2-(4-bromophenyl)-2-hydroxyethyl]-3-methyl-piperidin-4-yl]-N-phenylacrylamide.
Acta crystallographica. Section C, Crystal structure communications 2002;58(Pt 6):o362-4.
2002: Judith L Flippen-Anderson; Jeffrey Deschamps; Clifford George; V J Hruby; Aleksandra Misicka; Andrzej W Lipkowski
Crystal structure of biphalin sulfate: a multireceptor opioid peptide.
The journal of peptide research : official journal of the American Peptide Society 2002;59(3):123-33.
2002: Jeffrey Deschamps; Judith L Flippen-Anderson; Clifford George
X-ray studies on ligands.
Biopolymers 2002;66(5):287-93.
1999: V Monaco; Fernando Formaggio; Marco Crisma; Claudio Toniolo; P Hanson; Glenn L Millhauser; C George; Jeffrey Deschamps; Judith L Flippen-Anderson
Determining the occurrence of a 3(10)-helix and an alpha-helix in two different segments of a lipopeptaibol antibiotic using TOAC, a nitroxide spin-labeled C(alpha)-tetrasubstituted alpha-aminoacid.
Bioorganic & medicinal chemistry 1999;7(1):119-31.
1997: Jeffrey Deschamps; Judith L Flippen-Anderson; C Moore; R Cudney; Clifford George
Tyrosinium-D-tetrahydroisoquinoline-3-carboxylate 1.5-hydrate and tyrosyl-D-tetrahydroisoquinoline-3-carboxamide hydrate.
Acta crystallographica. Section C, Crystal structure communications 1997;53 ( Pt 10)():1478-82.
1997: Judith L Flippen-Anderson; Jeffrey Deschamps; Clifford George; P A Reddy; A H Lewin; G A Brine; G Sheldrick; G Nikiforovich
X-ray structure of Tyr-D-Tic-Phe-Phe-NH2 (D-TIPP-NH2), a highly potent mu-receptor selective opioid agonist. Comparison with proposed model structures.
The journal of peptide research : official journal of the American Peptide Society 1997;49(5):384-93.
1996: Jeffrey Deschamps; Clifford George; Judith L Flippen-Anderson
[D-Ala2,D-Leu5]-enkephalin hydrochloride.
Acta crystallographica. Section C, Crystal structure communications 1996;52 ( Pt 6)():1583-5.
1996: Jeffrey Deschamps; Clifford George; Judith L Flippen-Anderson
A diacetylmorphine polymorph.
Acta crystallographica. Section C, Crystal structure communications 1996;52 ( Pt 3)():698-700.
1996: Jeffrey Deschamps; Clifford George; Judith L Flippen-Anderson
Structural studies of opioid peptides: a review of recent progress in x-ray diffraction studies.
Biopolymers 1996;40(1):121-39.
1995: Jeffrey Deschamps; C E Miller; K B Ward
Rapid purification of recombinant green fluorescent protein using the hydrophobic properties of an HPLC size-exclusion column.
Protein expression and purification 1995;6(4):555-8.
1994: Judith L Flippen-Anderson; Jeffrey Deschamps; K B Ward; Clifford George; R Houghten
Crystal structure of deltakephalin: a delta-selective opioid peptide with a novel beta-bend-like conformation.
International journal of peptide and protein research 1994;44(2):97-104.
1994: Judith L Flippen-Anderson; Clifford George; Jeffrey Deschamps
Methyl N,N-diallyl-O-tert-butyltyrosyl-alpha-aminoisobutyrl-alpha- aminoisobutyrate, C28H43N3O5.
Acta crystallographica. Section C, Crystal structure communications 1994;50 ( Pt 7)():1095-7.
1993: Jeffrey Deschamps; K Kopec-Smyth; J L Poppino; S L Futrovsky; K B Ward
Comparison of organophosphorous acid anhydrolases from different species using monoclonal antibodies.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1993;106(3):765-8.
1993: K Kopec-Smyth; Jeffrey Deschamps; L D Loomis; K B Ward
A partial primary structure of squid hepatopancreas organophosphorus acid anhydrolase.
Chemico-biological interactions 1993;87(1-3):49-54.
1993: L I Hannick; Douglas Prasher; L W Schultz; Jeffrey Deschamps; K B Ward
Preparation and initial characterization of crystals of the photoprotein aequorin from Aequorea victoria.
Proteins 1993;15(1):103-7.
1985: Jeffrey Deschamps; James E K Hildreth; D Derr; Thomas August
A high-performance liquid chromatographic procedure for the purification of mouse monoclonal antibodies.
Analytical biochemistry 1985;147(2):451-4.