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Neil stahl

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Chemicals & Drugs

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Neil stahl; Allen Radin; Scott Mellis
Rilonacept--CAPS and beyond.
Hal M Hoffman; Martin L Throne; N J Amar; Mohamed Sebai; Alan J Kivitz; Arthur Kavanaugh; Steven P Weinstein; Pavel Belomestnov; George D Yancopoulos; Neil stahl; Scott Mellis
Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies.
John S Rudge; Jocelyn Holash; Donna Hylton; Michelle Russell; Shelly Jiang; Raymond Leidich; Nick Papadopoulos; Erica A Pyles; Al Torri; Stanley J Wiegand; Gavin Thurston; Neil stahl; George D Yancopoulos
VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade.

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All Publications

2009: Neil stahl; Allen Radin; Scott Mellis
Rilonacept--CAPS and beyond.
Annals of the New York Academy of Sciences 2009;1182():124-34.
2008: Hal M Hoffman; Martin L Throne; N J Amar; Mohamed Sebai; Alan J Kivitz; Arthur Kavanaugh; Steven P Weinstein; Pavel Belomestnov; George D Yancopoulos; Neil stahl; Scott Mellis
Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies.
Arthritis and rheumatism 2008;58(8):2443-52.
2007: John S Rudge; Jocelyn Holash; Donna Hylton; Michelle Russell; Shelly Jiang; Raymond Leidich; Nick Papadopoulos; Erica A Pyles; Al Torri; Stanley J Wiegand; Gavin Thurston; Neil stahl; George D Yancopoulos
VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(47):18363-70.
2003: David L Glaser; Aris N Economides; Lili Wang; Xia Liu; Robert D Kimble; James P Fandl; James M Wilson; Neil stahl; Frederick S Kaplan; Eileen M Shore
In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification.
The Journal of bone and joint surgery. American volume 2003;85-A(12):2332-42.
2003: Aris N Economides; Laura Rocco Carpenter; John S Rudge; Vivien Wong; Ellen M Koehler-Stec; Christopher Hartnett; Erica A Pyles; Xiaobing Xu; Thomas J Daly; Michael R Young; James P Fandl; Frank Lee; Scott Carver; Jennifer McNay; Kevin Bailey; Swayampakula Ramakanth; Renta Hutabarat; Tammy T Huang; Czeslaw Radziejewski; George D Yancopoulos; Neil stahl
Cytokine traps: multi-component, high-affinity blockers of cytokine action.
Nature medicine 2003;9(1):47-52.
2000: Etsuko Abe; M Yamamoto; Y Taguchi; Beata Lecka-Czernik; Charles A O'Brien; Aris N Economides; Neil stahl; Robert L Jilka; Stavros C Manolagas
Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(4):663-73.
1999: Ramón Merino; Domingo Macias; Yolanda Gañan; Aris N Economides; X Wang; Q Wu; Neil stahl; K T Sampath; P Varona; Juan M Hurle
Expression and function of Gdf-5 during digit skeletogenesis in the embryonic chick leg bud.
Developmental biology 1999;206(1):33-45.
1998: Jay Groppe; K Rumpel; Aris N Economides; Neil stahl; W Sebald; Markus Affolter
Biochemical and biophysical characterization of refolded Drosophila DPP, a homolog of bone morphogenetic proteins 2 and 4.
The Journal of biological chemistry 1998;273(44):29052-65.
1998: Joachim Weis; DC Lie; U Ragoss; Stephan Zuchner; J Michael Schröder; G Karpati; TJ Farruggella; Neil stahl; George D Yancopoulos; P S DiStefano
Increased expression of CNTF receptor alpha in denervated human skeletal muscle.
Journal of neuropathology and experimental neurology 1998;57(9):850-7.
1998: Laura Rocco Carpenter; TJ Farruggella; AJ Symes; M L Karow; George D Yancopoulos; Neil stahl
Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6061-6.
1998: Laura Rocco Carpenter; George D Yancopoulos; Neil stahl
General mechanisms of cytokine receptor signaling.
Advances in protein chemistry 1998;52():109-40.
1997: Beth A Habecker; AJ Symes; Neil stahl; Nicole Francis; Aris N Economides; J Stephen Fink; George D Yancopoulos; Story C Landis
A sweat gland-derived differentiation activity acts through known cytokine signaling pathways.
The Journal of biological chemistry 1997;272(48):30421-8.
1997: Azad Bonni; Yi E Sun; M Nadal-Vicens; A Bhatt; David A Frank; I Rozovsky; Neil stahl; George D Yancopoulos; Michael E Greenberg
Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway.
Science (New York, N.Y.) 1997;278(5337):477-83.
1997: AJ Symes; Neil stahl; Steven A Reeves; TJ Farruggella; T Servidei; Tom Gearan; George D Yancopoulos; J Stephen Fink
The protein tyrosine phosphatase SHP-2 negatively regulates ciliary neurotrophic factor induction of gene expression.
Current biology : CB 1997;7(9):697-700.
1997: M Faris; N Kokot; Neil stahl; Andre E Nel
Involvement of Stat3 in interleukin-6-induced IgM production in a human B-cell line.
Immunology 1997;90(3):350-7.
1996: M Faris; B Ensoli; Neil stahl; George D Yancopoulos; A Nguyen; S Wang; Andre E Nel
Differential activation of the extracellular signal-regulated kinase, Jun kinase and Janus kinase-Stat pathways by oncostatin M and basic fibroblast growth factor in AIDS-derived Kaposi's sarcoma cells.
AIDS (London, England) 1996;10(4):369-78.
1996: Teresita Bellido; Neil stahl; T J Farruggella; V Borba; George D Yancopoulos; Stavros C Manolagas
Detection of receptors for interleukin-6, interleukin-11, leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in bone marrow stromal/osteoblastic cells.
The Journal of clinical investigation 1996;97(2):431-7.
1995: Aris N Economides; J V Ravetch; George D Yancopoulos; Neil stahl
Designer cytokines: targeting actions to cells of choice.
Science (New York, N.Y.) 1995;270(5240):1351-3.
1995: Thomas M DeChiara; R Vejsada; W T Poueymirou; AL Acheson; Chitra Suri; J C Conover; B Friedman; Joyce McClain; L Pan; Neil stahl; Nancy Y Ip; George D Yancopoulos
Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth.
Cell 1995;83(2):313-22.
1995: T G Boulton; Z Zhong; Z Wen; James E Darnell; Neil stahl; George D Yancopoulos
STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(15):6915-9.
1995: Neil stahl; T J Farruggella; T G Boulton; Z Zhong; James E Darnell; George D Yancopoulos
Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors.
Science (New York, N.Y.) 1995;267(5202):1349-53.
1995: V Wong; D Pearsall; R Arriaga; Nancy Y Ip; Neil stahl; RM Lindsay
Binding characteristics of ciliary neurotrophic factor to sympathetic neurons and neuronal cell lines.
The Journal of biological chemistry 1995;270(1):313-8.
1994: Neil stahl; George D Yancopoulos
The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines.
Journal of neurobiology 1994;25(11):1454-66.
1994: T G Boulton; Neil stahl; George D Yancopoulos
Ciliary neurotrophic factor/leukemia inhibitory factor/interleukin 6/oncostatin M family of cytokines induces tyrosine phosphorylation of a common set of proteins overlapping those induced by other cytokines and growth factors.
The Journal of biological chemistry 1994;269(15):11648-55.
1994: Neil stahl; T G Boulton; Nancy Y Ip; Samuel Davis; George D Yancopoulos
The tails of two proteins: the scrapie prion protein and the ciliary neurotrophic factor receptor.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(2):297-301.
1994: Neil stahl; T G Boulton; T Farruggella; Nancy Y Ip; Samuel Davis; bruce witthuhn; F W Quelle; O Silvennoinen; G Barbieri; Sandra Pellegrini
Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.
Science (New York, N.Y.) 1994;263(5143):92-5.
1993: T M Lamb; A K Knecht; W C Smith; S E Stachel; Aris N Economides; Neil stahl; G D Yancopolous; Richard M Harland
Neural induction by the secreted polypeptide noggin.
Science (New York, N.Y.) 1993;262(5134):713-8.
1993: Neil stahl; George D Yancopoulos
The alphas, betas, and kinases of cytokine receptor complexes.
Cell 1993;74(4):587-90.
1993: David R Borchelt; M Rogers; Neil stahl; Glenn C Telling; Stanley B Prusiner
Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor.
Glycobiology 1993;3(4):319-29.
1993: Samuel Davis; Thomas H Aldrich; Neil stahl; L Pan; T Taga; T Kishimoto; Nancy Y Ip; George D Yancopoulos
LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor.
Science (New York, N.Y.) 1993;260(5115):1805-8.
1993: Neil stahl; S Davis; V Wong; Tetsuya Taga; Tadamitsu Kishimoto; N Y Ip; George D Yancopoulos
Cross-linking identifies leukemia inhibitory factor-binding protein as a ciliary neurotrophic factor receptor component.
The Journal of biological chemistry 1993;268(11):7628-31.
1993: Stanley B Prusiner; Darlene Groth; A Serban; Neil stahl; Ruth Gabizon
Attempts to restore scrapie prion infectivity after exposure to protein denaturants.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2793-7.
1993: Samuel Davis; Thomas H Aldrich; Nancy Y Ip; Neil stahl; S Scherer; T Farruggella; PS DiStefano; Rory Curtis; N Panayotatos; H Gascan
Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses.
Science (New York, N.Y.) 1993;259(5102):1736-9.
1993: Neil stahl; Michael A Baldwin; David B Teplow; L Hood; Bradford W Gibson; Al L Burlingame; Stanley B Prusiner
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.
Biochemistry 1993;32(8):1991-2002.
1992: K M Pan; Neil stahl; Stanley B Prusiner
Purification and properties of the cellular prion protein from Syrian hamster brain.
Protein science : a publication of the Protein Society 1992;1(10):1343-52.
1992: Neil stahl; Michael A Baldwin; R Hecker; K M Pan; Al L Burlingame; Stanley B Prusiner
Glycosylinositol phospholipid anchors of the scrapie and cellular prion proteins contain sialic acid.
Biochemistry 1992;31(21):5043-53.
1991: Neil stahl; Stanley B Prusiner
Prions and prion proteins.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(13):2799-807.
1991: Neil stahl; Michael A Baldwin; Stanley B Prusiner
Electrospray mass spectrometry of the glycosylinositol phospholipid of the scrapie prion protein.
Cell biology international reports 1991;15(9):853-62.
1990: Michael A Baldwin; Neil stahl; L G Reinders; Bradford W Gibson; Stanley B Prusiner; Al L Burlingame
Permethylation and tandem mass spectrometry of oligosaccharides having free hexosamine: analysis of the glycoinositol phospholipid anchor glycan from the scrapie prion protein.
Analytical biochemistry 1990;191(1):174-82.
1990: Neil stahl; Michael A Baldwin; Al L Burlingame; Stanley B Prusiner
Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein.
Biochemistry 1990;29(38):8879-84.
1990: Bruno Oesch; David B Teplow; Neil stahl; D Serban; L E Hood; Stanley B Prusiner
Identification of cellular proteins binding to the scrapie prion protein.
Biochemistry 1990;29(24):5848-55.
1990: Neil stahl; David R Borchelt; Stanley B Prusiner
Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C.
Biochemistry 1990;29(22):5405-12.
1990: David R Borchelt; Michael Scott; A Taraboulos; Neil stahl; Stanley B Prusiner
Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells.
The Journal of cell biology 1990;110(3):743-52.
1988: Christopher Miller; Neil stahl; M Barrol
A thermodynamic analysis of monovalent cation permeation through a K(+)-selective ion channel.
Neuron 1988;1(2):159-64.
1988: Stanley B Prusiner; Neil stahl; Stephen J DeArmond
Novel mechanisms of degeneration of the central nervous system--prion structure and biology.
Ciba Foundation symposium 1988;135():239-60.
1987: Neil stahl; W P Jencks
Reactions of the sarcoplasmic reticulum calcium adenosinetriphosphatase with adenosine 5'-triphosphate and Ca2+ that are not satisfactorily described by an E1-E2 model.
Biochemistry 1987;26(24):7654-67.
1987: Neil stahl; David R Borchelt; Karen K. Hsiao Ashe; Stanley B Prusiner
Scrapie prion protein contains a phosphatidylinositol glycolipid.
Cell 1987;51(2):229-40.
1984: Neil stahl; W P Jencks
Adenosine 5'-triphosphate at the active site accelerates binding of calcium to calcium adenosinetriphosphatase.
Biochemistry 1984;23(23):5389-92.