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Douglas Lowy

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Patricia M Day; Douglas Lowy; Rachel M Schowalter; Cynthia D Thompson; John T Schiller
Identification of a role for the trans-Golgi network in human papillomavirus 16 pseudovirus infection.
Aimée R Kreimer; Douglas Lowy; Carolina Porras; Wim Quint; Ana Cecilia Rodriguez; Mark Schiffman; John T Schiller; John E Schussler; Mark E Sherman; Diane Solomon; Sholom Wacholder; Paula González; Rolando Herrero; Allan Hildesheim; Silvia Jiménez
Proof-of-principle evaluation of the efficacy of fewer than three doses of a bivalent HPV16/18 vaccine.
Jeffrey N Roberts; Rhonda C Kines; Hormuzd A Katki; Douglas Lowy; John T Schiller
Effect of Pap smear collection and carrageenan on cervicovaginal human papillomavirus-16 infection in a rhesus macaque model.

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All Publications

2013: Patricia M Day; Douglas Lowy; Rachel M Schowalter; Cynthia D Thompson; John T Schiller
Identification of a role for the trans-Golgi network in human papillomavirus 16 pseudovirus infection.
Journal of virology 2013;87(7):3862-70.
2011: Aimée R Kreimer; Douglas Lowy; Carolina Porras; Wim Quint; Ana Cecilia Rodriguez; Mark Schiffman; John T Schiller; John E Schussler; Mark E Sherman; Diane Solomon; Sholom Wacholder; Paula González; Rolando Herrero; Allan Hildesheim; Silvia Jiménez
Proof-of-principle evaluation of the efficacy of fewer than three doses of a bivalent HPV16/18 vaccine.
Journal of the National Cancer Institute 2011;103(19):1444-51.
2011: Jeffrey N Roberts; Rhonda C Kines; Hormuzd A Katki; Douglas Lowy; John T Schiller
Effect of Pap smear collection and carrageenan on cervicovaginal human papillomavirus-16 infection in a rhesus macaque model.
Journal of the National Cancer Institute 2011;103(9):737-43.
2011: Makoto Mitsunaga; Nobuyuki Kosaka; Rhonda C Kines; Jeffrey N Roberts; Douglas Lowy; John T Schiller; Yasushige Ishihara; Akira Hasegawa; Peter L Choyke; Hisataka Kobayashi
In vivo longitudinal imaging of experimental human papillomavirus infection in mice with a multicolor fluorescence mini-endoscopy system.
Cancer prevention research (Philadelphia, Pa.) 2011;4(5):767-73.
2010: L Asnaghi; William C Vass; R Quadri; Patricia M Day; Xiaolan Qian; Richard Braverman; Alex G Papageorge; Douglas Lowy
E-cadherin negatively regulates neoplastic growth in non-small cell lung cancer: role of Rho GTPases.
Oncogene 2010;29(19):2760-71.
2009: Rhonda C Kines; Cynthia D Thompson; Douglas Lowy; John T Schiller; Patricia M Day
The initial steps leading to papillomavirus infection occur on the basement membrane prior to cell surface binding.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(48):20458-63.
2009: Xiaolan Qian; Guorong Li; William C Vass; Alex Papageorge; Renard C Walker; Laura Asnaghi; Peter J Steinbach; Giovanna Tosato; Kent Hunter; Douglas Lowy
The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis.
Cancer cell 2009;16(3):246-58.
2009: John T Schiller; Douglas Lowy
Immunogenicity testing in human papillomavirus virus-like-particle vaccine trials.
The Journal of infectious diseases 2009;200(2):166-71.
2009: Subhashini Jagu; Balasubramanyam Karanam; Ratish Gambhira; Sudha V Chivukula; Revathi J Chaganti; Douglas Lowy; John T Schiller; Richard B S Roden
Concatenated multitype L2 fusion proteins as candidate prophylactic pan-human papillomavirus vaccines.
Journal of the National Cancer Institute 2009;101(11):782-92.
2009: X-Y Yang; M Guan; Dominico Vigil; Channing J Der; Douglas Lowy; Nicholas C Popescu
p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities.
Oncogene 2009;28(11):1401-9.
2009: Katherine M Johnson; Rhonda C Kines; Jeffrey N Roberts; Douglas Lowy; John T Schiller; Patricia M Day
Role of heparan sulfate in attachment to and infection of the murine female genital tract by human papillomavirus.
Journal of virology 2009;83(5):2067-74.
2009: Alfonso J García-Piñeres; Allan Hildesheim; Lori Dodd; Troy J Kemp; Jun Yang; Brandie Fullmer; Clayton D Harro; Douglas Lowy; Richard A Lempicki; Ligia A Pinto
Gene expression patterns induced by HPV-16 L1 virus-like particles in leukocytes from vaccine recipients.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(3):1706-29.
2009: Christopher B Buck; Douglas Lowy
Getting stronger: the relationship between a newly identified virus and Merkel cell carcinoma.
The Journal of investigative dermatology 2009;129(1):9-11.
2008: Patricia M Day; Douglas Lowy; John T Schiller
Heparan sulfate-independent cell binding and infection with furin-precleaved papillomavirus capsids.
Journal of virology 2008;82(24):12565-8.
2008: Maura L Gillison; Anil K Chaturvedi; Douglas Lowy
HPV prophylactic vaccines and the potential prevention of noncervical cancers in both men and women.
Cancer 2008;113(10 Suppl):3036-46.
2008: Douglas Lowy; Diane Solomon; Allan Hildesheim; John T Schiller; Mark Schiffman
Human papillomavirus infection and the primary and secondary prevention of cervical cancer.
Cancer 2008;113(7 Suppl):1980-93.
2008: Rolando Herrero; Allan Hildesheim; Ana C Rodríguez; Sholom Wacholder; Concepción Bratti; Diane Solomon; Paula González; Carolina Porras; Silvia Jiménez; Diego Guillen; Jorge Morales; Mario Alfaro; Jean Cyr; Kerrygrace Morrisey; Yenory Estrada; Bernal Cortés; Lidia Ana Morera; Enrique Freer; John Schussler; John Schiller; Douglas Lowy; Mark Schiffman
Rationale and design of a community-based double-blind randomized clinical trial of an HPV 16 and 18 vaccine in Guanacaste, Costa Rica.
Vaccine 2008;26(37):4795-808.
2008: Douglas Lowy
Human papillomavirus, cervical cancer prevention, and more.
Vaccine 2008;26 Suppl 10():iii-iv.
2008: Christopher B Buck; Naiqian Cheng; Cynthia D Thompson; Douglas Lowy; Alasdair C Steven; John T Schiller; Benes Trus
Arrangement of L2 within the papillomavirus capsid.
Journal of virology 2008;82(11):5190-7.
2008: Patricia M Day; Ratish Gambhira; Richard B S Roden; Douglas Lowy; John T Schiller
Mechanisms of human papillomavirus type 16 neutralization by l2 cross-neutralizing and l1 type-specific antibodies.
Journal of virology 2008;82(9):4638-46.
2008: Troy J Kemp; Allan Hildesheim; Roni T Falk; John T Schiller; Douglas Lowy; Ana Cecilia Rodriguez; Ligia A Pinto
Evaluation of two types of sponges used to collect cervical secretions and assessment of antibody extraction protocols for recovery of neutralizing anti-human papillomavirus type 16 antibodies.
Clinical and vaccine immunology : CVI 2008;15(1):60-4.
2007: Nigel Crawford; Xiaolan Qian; Argyrios Ziogas; Alex G Papageorge; Brenda J Boersma; Renard C Walker; Luanne Lukes; William L Rowe; Jinghui Zhang; Stefan Ambs; Douglas Lowy; Hoda Anton-Culver; Kent W Hunter
Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis.
PLoS genetics 2007;3(11):e214.
2007: Ian H Frazer; Douglas Lowy; John T Schiller
Prevention of cancer through immunization: Prospects and challenges for the 21st century.
European journal of immunology 2007;37 Suppl 1():S148-55.
2007: Marian E Durkin; Bao-Zhu Yuan; Xiaoling Zhou; Drazen Zimonjic; Douglas Lowy; Snorri S Thorgeirsson; Nicholas C Popescu
DLC-1:a Rho GTPase-activating protein and tumour suppressor.
Journal of cellular and molecular medicine 2007;11(5):1185-207.
2007: Douglas Lowy
Aaron Lerner: a mentor and friend.
The Journal of investigative dermatology 2007;127(9):2092.
2007: Allan Hildesheim; Rolando Herrero; Sholom Wacholder; Ana Cecilia Rodriguez; Diane Solomon; M Concepcion Bratti; John T Schiller; Paula Gonzalez; Gary Dubin; Carolina Porras; Silvia E Jimenez; Douglas Lowy
Effect of human papillomavirus 16/18 L1 viruslike particle vaccine among young women with preexisting infection: a randomized trial.
JAMA : the journal of the American Medical Association 2007;298(7):743-53.
2007: Alfonso J García-Piñeres; Allan Hildesheim; Lori Dodd; Troy J Kemp; Marcus Williams; Clayton D Harro; Douglas Lowy; John T Schiller; Ligia A Pinto
Cytokine and chemokine profiles following vaccination with human papillomavirus type 16 L1 Virus-like particles.
Clinical and vaccine immunology : CVI 2007;14(8):984-9.
2007: Patricia M Day; Cynthia D Thompson; Christopher B Buck; Yuk-Ying S Pang; Douglas Lowy; John T Schiller
Neutralization of human papillomavirus with monoclonal antibodies reveals different mechanisms of inhibition.
Journal of virology 2007;81(16):8784-92.
2007: Jeffrey N Roberts; Christopher B Buck; Cynthia D Thompson; Rhonda Kines; Marcelino Bernardo; Peter L Choyke; Douglas Lowy; John T Schiller
Genital transmission of HPV in a mouse model is potentiated by nonoxynol-9 and inhibited by carrageenan.
Nature medicine 2007;13(7):857-61.
2007: Xiaolan Qian; Guorong Li; Holly K Asmussen; Laura Asnaghi; William C Vass; Richard Braverman; Kenneth M Yamada; Nicholas C Popescu; Alex G Papageorge; Douglas Lowy
Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):9012-7.
2006: John T Schiller; Douglas Lowy
Prospects for cervical cancer prevention by human papillomavirus vaccination.
Cancer research 2006;66(21):10229-32.
2006: Ligia A Pinto; Raphael P Viscidi; Clayton D Harro; Troy J Kemp; Alfonso J García-Piñeres; Matthew Trivett; Franklin Demuth; Douglas Lowy; John T Schiller; Jay A Berzofsky; Allan Hildesheim
Cellular immune responses to HPV-18, -31, and -53 in healthy volunteers immunized with recombinant HPV-16 L1 virus-like particles.
Virology 2006;353(2):451-62.
2006: Margaret Stanley; Douglas Lowy; Ian Frazer
Chapter 12: Prophylactic HPV vaccines: underlying mechanisms.
Vaccine 2006;24 Suppl 3():S3/106-13.
2006: Christopher B Buck; Cynthia D Thompson; Jeffrey N Roberts; Martin Müller; Douglas Lowy; John T Schiller
Carrageenan is a potent inhibitor of papillomavirus infection.
PLoS pathogens 2006;2(7):e69.
2006: Douglas Lowy; John T Schiller
Prophylactic human papillomavirus vaccines.
The Journal of clinical investigation 2006;116(5):1167-73.
2006: Christopher B Buck; Patricia M Day; Cynthia D Thompson; Jacek Lubkowski; Wuyuan Lu; Douglas Lowy; John T Schiller
Human alpha-defensins block papillomavirus infection.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1516-21.
2006: Rebecca M Richards; Douglas Lowy; John T Schiller; Patricia M Day
Cleavage of the papillomavirus minor capsid protein, L2, at a furin consensus site is necessary for infection.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1522-7.
2005: Yeong-Gwan Park; Xiaohong Zhao; Fabienne LESUEUR; Douglas Lowy; Mindy Lancaster; Paul Pharoah; Xiaolan Qian; Kent W Hunter
Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1.
Nature genetics 2005;37(10):1055-62.
2005: Diana V Pastrana; Ratish Gambhira; Christopher B Buck; Yuk-Ying S Pang; Cynthia D Thompson; Timothy D Culp; Neil Christensen; Douglas Lowy; John T Schiller; Richard B S Roden
Cross-neutralization of cutaneous and mucosal Papillomavirus types with anti-sera to the amino terminus of L2.
Virology 2005;337(2):365-72.
2005: Denise Nardelli-Haefliger; Floriana Lurati; Daniel Wirthner; François Spertini; John T Schiller; Douglas Lowy; Françoise Ponci; Pierre De Grandi
Immune responses induced by lower airway mucosal immunisation with a human papillomavirus type 16 virus-like particle vaccine.
Vaccine 2005;23(28):3634-41.
2005: Ligia A Pinto; Philip E Castle; Richard B S Roden; Clayton D Harro; Douglas Lowy; John T Schiller; Dora Wallace; Marcus Williams; William Kopp; Ian H Frazer; Jay A Berzofsky; Allan Hildesheim
HPV-16 L1 VLP vaccine elicits a broad-spectrum of cytokine responses in whole blood.
Vaccine 2005;23(27):3555-64.
2005: Petra Lenz; Douglas Lowy; John T Schiller
Papillomavirus virus-like particles induce cytokines characteristic of innate immune responses in plasmacytoid dendritic cells.
European journal of immunology 2005;35(5):1548-56.
2005: Christopher B Buck; Cynthia D Thompson; Yuk-Ying S Pang; Douglas Lowy; John T Schiller
Maturation of papillomavirus capsids.
Journal of virology 2005;79(5):2839-46.
2005: Christopher B Buck; Diana V Pastrana; Douglas Lowy; John T Schiller
Generation of HPV pseudovirions using transfection and their use in neutralization assays.
Methods in molecular medicine 2005;119():445-62.
2004: Patricia M Day; Carl Baker; Douglas Lowy; John T Schiller
Establishment of papillomavirus infection is enhanced by promyelocytic leukemia protein (PML) expression.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(39):14252-7.
2004: Maura L Gillison; Douglas Lowy
A causal role for human papillomavirus in head and neck cancer.
Lancet 2004;363(9420):1488-9.
2004: Xiaolan Qian; Tatiana S Karpova; Allan M Sheppard; James McNally; Douglas Lowy
E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases.
The EMBO journal 2004;23(8):1739-48.
2004: Diana V Pastrana; Christopher B Buck; Yuk-Ying S Pang; Cynthia D Thompson; Philip E Castle; Peter C FitzGerald; Susanne Krüger-Kjaer; Douglas Lowy; John T Schiller
Reactivity of human sera in a sensitive, high-throughput pseudovirus-based papillomavirus neutralization assay for HPV16 and HPV18.
Virology 2004;321(2):205-16.
2004: Bryce Chackerian; Lindsey Briglio; Paul S Albert; Douglas Lowy; John T Schiller
Induction of autoantibodies to CCR5 in macaques and subsequent effects upon challenge with an R5-tropic simian/human immunodeficiency virus.
Journal of virology 2004;78(8):4037-47.
2004: Christopher B Buck; Diana V Pastrana; Douglas Lowy; John T Schiller
Efficient intracellular assembly of papillomaviral vectors.
Journal of virology 2004;78(2):751-7.
2003: Valery Bliskovsky; Edward S Ramsay; John Scott; Wendy DuBois; Wei Shi; Shuling Zhang; Xiaolan Qian; Douglas Lowy; Beverly A Mock
Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14982-7.
2003: Douglas Lowy; Maura L Gillison
A new link between Fanconi anemia and human papillomavirus-associated malignancies.
Journal of the National Cancer Institute 2003;95(22):1648-50.
2003: Denise Nardelli-Haefliger; Daniel Wirthner; John T Schiller; Douglas Lowy; Allan Hildesheim; Françoise Ponci; Pierre De Grandi
Specific antibody levels at the cervix during the menstrual cycle of women vaccinated with human papillomavirus 16 virus-like particles.
Journal of the National Cancer Institute 2003;95(15):1128-37.
2003: Ligia A Pinto; Jessica Edwards; Philip E Castle; Clayton D Harro; Douglas Lowy; John T Schiller; Dora Wallace; William Kopp; Joseph W Adelsberger; Michael Baseler; Jay A Berzofsky; Allan Hildesheim
Cellular immune responses to human papillomavirus (HPV)-16 L1 in healthy volunteers immunized with recombinant HPV-16 L1 virus-like particles.
The Journal of infectious diseases 2003;188(2):327-38.
2003: Shaowei Li; Richard Braverman; Hongzhen Li; William C Vass; Douglas Lowy; Jeffrey E DeClue
Regulation of cell morphology and adhesion by the tuberous sclerosis complex (TSC1/2) gene products in human kidney epithelial cells through increased E-cadherin/beta-catenin activity.
Molecular carcinogenesis 2003;37(2):98-109.
2003: Shuling Zhang; Xiaolan Qian; Chanelle Redman; Valery Bliskovski; Edward S Ramsay; Douglas Lowy; Beverly A Mock
p16 INK4a gene promoter variation and differential binding of a repressor, the ras-responsive zinc-finger transcription factor, RREB.
Oncogene 2003;22(15):2285-95.
2003: Petra Lenz; Cynthia D Thompson; Patricia M Day; Silvia M Bacot; Douglas Lowy; John T Schiller
Interaction of papillomavirus virus-like particles with human myeloid antigen-presenting cells.
Clinical immunology (Orlando, Fla.) 2003;106(3):231-7.
2003: Patricia M Day; Douglas Lowy; John T Schiller
Papillomaviruses infect cells via a clathrin-dependent pathway.
Virology 2003;307(1):1-11.
2003: Douglas Lowy; Ian H Frazer
Chapter 16: Prophylactic human papillomavirus vaccines.
Journal of the National Cancer Institute. Monographs 2003;(31):111-6.
2002: Bryce Chackerian; Petra Lenz; Douglas Lowy; John T Schiller
Determinants of autoantibody induction by conjugated papillomavirus virus-like particles.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(11):6120-6.
2001: Richard B S Roden; Patricia M Day; B K Bronzo; Wil Yutzy; Y Yang; Douglas Lowy; John T Schiller
Positively charged termini of the L2 minor capsid protein are necessary for papillomavirus infection.
Journal of virology 2001;75(21):10493-7.
2001: F X Bosch; N Muñoz; S de Sanjosé; E L Franco; Douglas Lowy; M Schiffman; S Franceschi; S K Kjaer; C J Meijer; I H Frazer; Jack Cuzick
Re: Cervical carcinoma and human papillomavirus: on the road to preventing a major human cancer.
Journal of the National Cancer Institute 2001;93(17):1349-50.
2001: Bryce Chackerian; Douglas Lowy; John T Schiller
Conjugation of a self-antigen to papillomavirus-like particles allows for efficient induction of protective autoantibodies.
The Journal of clinical investigation 2001;108(3):415-23.
2001: John T Schiller; Douglas Lowy
Papillomavirus-like particle based vaccines: cervical cancer and beyond.
Expert opinion on biological therapy 2001;1(4):571-81.
2001: Petra Lenz; Patricia M Day; Yuk-Ying S Pang; Stephan Frye; P N Jensen; Douglas Lowy; John T Schiller
Papillomavirus-like particles induce acute activation of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(9):5346-55.
2001: M M Okun; Patricia M Day; HL Greenstone; frank booy; Douglas Lowy; John T Schiller; Richard B S Roden
L1 interaction domains of papillomavirus l2 necessary for viral genome encapsidation.
Journal of virology 2001;75(9):4332-42.
2001: Clayton D Harro; Yuk-Ying S Pang; Richard B S Roden; Allan Hildesheim; Z Wang; M J Reynolds; T C Mast; R Robinson; Brian Murphy; Ruth A Karron; J Dillner; John T Schiller; Douglas Lowy
Safety and immunogenicity trial in adult volunteers of a human papillomavirus 16 L1 virus-like particle vaccine.
Journal of the National Cancer Institute 2001;93(4):284-92.
2001: Susanne Krüger Kjaer; Bryce Chackerian; Adriaan J C van den Brule; Edith Ingerslev Svare; G Paull; J M Walbomers; John T Schiller; Johannes E Bock; Mark E Sherman; Douglas Lowy; C L Meijer
High-risk human papillomavirus is sexually transmitted: evidence from a follow-up study of virgins starting sexual activity (intercourse).
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(2):101-6.
2001: Diana V Pastrana; William C Vass; Douglas Lowy; John T Schiller
NHPV16 VLP vaccine induces human antibodies that neutralize divergent variants of HPV16.
Virology 2001;279(1):361-9.
2001: John T Schiller; Douglas Lowy
Papillomavirus-like particle vaccines.
Journal of the National Cancer Institute. Monographs 2001;(28):50-4.
2000: Richard B S Roden; Wil Yutzy; R Fallon; S Inglis; Douglas Lowy; John T Schiller
Minor capsid protein of human genital papillomaviruses contains subdominant, cross-neutralizing epitopes.
Virology 2000;270(2):254-7.
2000: Xiaolan Qian; Luis Miguel Esteban; William C Vass; C Upadhyaya; Alex G Papageorge; K Yienger; Jerrold M Ward; Douglas Lowy; Eugenio Santos
The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties.
The EMBO journal 2000;19(4):642-54.
1999: P H Anborgh; Xiaolan Qian; Alex G Papageorge; William C Vass; Jeffrey E DeClue; Douglas Lowy
Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.
Molecular and cellular biology 1999;19(7):4611-22.
1999: Bryce Chackerian; Douglas Lowy; John T Schiller
Induction of autoantibodies to mouse CCR5 with recombinant papillomavirus particles.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2373-8.
1999: Douglas Lowy; John T Schiller
Papillomaviruses: prophylactic vaccine prospects.
Biochimica et biophysica acta 1999;1423(1):M1-8.
1998: ML De Bruijn; HL Greenstone; H Vermeulen; Cornelis J M Melief; Douglas Lowy; John T Schiller; W Martin Kast
L1-specific protection from tumor challenge elicited by HPV16 virus-like particles.
Virology 1998;250(2):371-6.
1998: HL Greenstone; JD Nieland; Karin E de Visser; ML De Bruijn; Reinhard Kirnbauer; Richard B S Roden; Douglas Lowy; W Martin Kast; John T Schiller
Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1800-5.
1998: Xiaolan Qian; William C Vass; Alex G Papageorge; P H Anborgh; Douglas Lowy
N terminus of Sos1 Ras exchange factor: critical roles for the Dbl and pleckstrin homology domains.
Molecular and cellular biology 1998;18(2):771-8.
1998: Douglas Lowy; John T Schiller
Papillomaviruses and cervical cancer: pathogenesis and vaccine development.
Journal of the National Cancer Institute. Monographs 1998;(23):27-30.
1998: Patricia M Day; Richard B S Roden; Douglas Lowy; John T Schiller
The papillomavirus minor capsid protein, L2, induces localization of the major capsid protein, L1, and the viral transcription/replication protein, E2, to PML oncogenic domains.
Journal of virology 1998;72(1):142-50.
1997: K H Nielsen; Alex G Papageorge; William C Vass; Berthe M Willumsen; Douglas Lowy
The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1.
Molecular and cellular biology 1997;17(12):7132-8.
1997: Richard B S Roden; Douglas Lowy; John T Schiller
Papillomavirus is resistant to desiccation.
The Journal of infectious diseases 1997;176(4):1076-9.
1997: Edith Ingerslev Svare; Susanne Krüger Kjaer; Bernadete Nonnenmacher; AM Worm; H Moi; R B Christensen; Adriaan J C van den Brule; JM Walboomers; Chris J L M Meijer; NL Hubbert; Douglas Lowy; John T Schiller
Seroreactivity to human papillomavirus type 16 virus-like particles is lower in high-risk men than in high-risk women.
The Journal of infectious diseases 1997;176(4):876-83.
1997: Richard B S Roden; A Armstrong; P Haderer; Neil Christensen; NL Hubbert; Douglas Lowy; John T Schiller; Reinhard Kirnbauer
Characterization of a human papillomavirus type 16 variant-dependent neutralizing epitope.
Journal of virology 1997;71(8):6247-52.
1997: Douglas Lowy
HPV infection: future prospects.
Clinics in dermatology 1997;15(2):299-302.
1997: A F Ferrier; M Lee; Wayne B Anderson; G Benvenuto; D K Morrison; Douglas Lowy; Jeffrey E DeClue
Sequential modification of serines 621 and 624 in the Raf-1 carboxyl terminus produces alterations in its electrophoretic mobility.
The Journal of biological chemistry 1997;272(4):2136-42.
1996: B Nonnenmacher; S Kruger Kjaer; Edith Ingerslev Svare; J D Scott; N L Hubbert; Adriaan J C van den Brule; Reinhard Kirnbauer; JM Walboomers; Douglas Lowy; John T Schiller
Seroreactivity to HPV16 virus-like particles as a marker for cervical cancer risk in high-risk populations.
International journal of cancer. Journal international du cancer 1996;68(6):704-9.
1996: John T Schiller; Douglas Lowy
Papillomavirus-like particles and HPV vaccine development.
Seminars in cancer biology 1996;7(6):373-82.
1996: L Leonardsen; Jeffrey E DeClue; H Lybaek; Douglas Lowy; Berthe M Willumsen
Rasp21 sequences opposite the nucleotide binding pocket are required for GRF-mediated nucleotide release.
Oncogene 1996;13(10):2177-87.
1996: Louise Wideroff; Mark Schiffman; Robert Hoover; R E Tarone; B Nonnenmacher; N Hubbert; Reinhard Kirnbauer; CE Greer; Attila T Lorincz; M Michele Manos; Andrew G. Glass; David R Scott; Mark E Sherman; J Buckland; Douglas Lowy; J Schiller
Epidemiologic determinants of seroreactivity to human papillomavirus (HPV) type 16 virus-like particles in cervical HPV-16 DNA-positive and-negative women.
The Journal of infectious diseases 1996;174(5):937-43.
1996: C Han; G Qiao; N L Hubbert; L Li; C Sun; Y Wang; M Yan; D Xu; Y Li; Douglas Lowy; John T Schiller
Serologic association between human papillomavirus type 16 infection and esophageal cancer in Shaanxi Province, China.
Journal of the National Cancer Institute 1996;88(20):1467-71.
1996: Richard B S Roden; HL Greenstone; Reinhard Kirnbauer; frank booy; J Jessie; Douglas Lowy; John T Schiller
In vitro generation and type-specific neutralization of a human papillomavirus type 16 virion pseudotype.
Journal of virology 1996;70(9):5875-83.
1996: Richard B S Roden; N L Hubbert; Reinhard Kirnbauer; Neil Christensen; Douglas Lowy; John T Schiller
Assessment of the serological relatedness of genital human papillomaviruses by hemagglutination inhibition.
Journal of virology 1996;70(5):3298-301.
1996: Reinhard Kirnbauer; L M Chandrachud; BW O'Neil; E R Wagner; G Joan Grindlay; A Armstrong; G M McGarvie; John T Schiller; Douglas Lowy; M Saveria Campo
Virus-like particles of bovine papillomavirus type 4 in prophylactic and therapeutic immunization.
Virology 1996;219(1):37-44.
1996: Douglas Lowy; John T Schiller
Human papillomavirus biology.
Journal of the National Cancer Institute. Monographs 1996;(21):141-3.
1995: G Cheng; Joseph P Icenogle; Reinhard Kirnbauer; N L Hubbert; Michael St. Louis; C Han; Edith Ingerslev Svare; Susanne Krüger Kjaer; Douglas Lowy; John T Schiller
Divergent human papillomavirus type 16 variants are serologically cross-reactive.
The Journal of infectious diseases 1995;172(6):1584-7.
1995: Louise Wideroff; Mark Schiffman; B Nonnenmacher; N Hubbert; Reinhard Kirnbauer; CE Greer; Douglas Lowy; Attila T Lorincz; M Michele Manos; Andrew G. Glass
Evaluation of seroreactivity to human papillomavirus type 16 virus-like particles in an incident case-control study of cervical neoplasia.
The Journal of infectious diseases 1995;172(6):1425-30.
1995: Douglas Lowy; Berthe M Willumsen
Rational cancer therapy.
Nature medicine 1995;1(8):747-8.
1995: Richard B S Roden; N L Hubbert; Reinhard Kirnbauer; Françoise Breitburd; Douglas Lowy; John T Schiller
Papillomavirus L1 capsids agglutinate mouse erythrocytes through a proteinaceous receptor.
Journal of virology 1995;69(8):5147-51.
1995: B Nonnenmacher; N L Hubbert; Reinhard Kirnbauer; Keerti V Shah; N Muñoz; F X Bosch; S de Sanjosé; Raphael P Viscidi; Douglas Lowy; John T Schiller
Serologic response to human papillomavirus type 16 (HPV-16) virus-like particles in HPV-16 DNA-positive invasive cervical cancer and cervical intraepithelial neoplasia grade III patients and controls from Colombia and Spain.
The Journal of infectious diseases 1995;172(1):19-24.
1995: Françoise Breitburd; Reinhard Kirnbauer; N L Hubbert; B Nonnenmacher; C Trin-Dinh-Desmarquet; Gérard Orth; John T Schiller; Douglas Lowy
Immunization with viruslike particles from cottontail rabbit papillomavirus (CRPV) can protect against experimental CRPV infection.
Journal of virology 1995;69(6):3959-63.
1994: R M Melillo; K Helin; Douglas Lowy; John T Schiller
Positive and negative regulation of cell proliferation by E2F-1: influence of protein level and human papillomavirus oncoproteins.
Molecular and cellular biology 1994;14(12):8241-9.
1994: Richard B S Roden; Reinhard Kirnbauer; A B Jenson; Douglas Lowy; John T Schiller
Interaction of papillomaviruses with the cell surface.
Journal of virology 1994;68(11):7260-6.
1994: Richard B S Roden; Eva M Weissinger; DW Henderson; frank booy; Reinhard Kirnbauer; J Frederic Mushinski; Douglas Lowy; John T Schiller
Neutralization of bovine papillomavirus by antibodies to L1 and L2 capsid proteins.
Journal of virology 1994;68(11):7570-4.
1994: Reinhard Kirnbauer; N L Hubbert; Cosette M Wheeler; Thomas M Becker; Douglas Lowy; John T Schiller
A virus-like particle enzyme-linked immunosorbent assay detects serum antibodies in a majority of women infected with human papillomavirus type 16.
Journal of the National Cancer Institute 1994;86(7):494-9.
1994: Douglas Lowy; Reinhard Kirnbauer; John T Schiller
Genital human papillomavirus infection.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2436-40.
1994: M R Johnson; Jeffrey E DeClue; S Felzmann; William C Vass; G Xu; R White; Douglas Lowy
Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function.
Molecular and cellular biology 1994;14(1):641-5.
1993: H Cen; Alex G Papageorge; William C Vass; K E Zhang; Douglas Lowy
Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor.
Molecular and cellular biology 1993;13(12):7718-24.
1993: Reinhard Kirnbauer; J Taub; HL Greenstone; Richard B S Roden; M Dürst; L Gissmann; Douglas Lowy; John T Schiller
Efficient self-assembly of human papillomavirus type 16 L1 and L1-L2 into virus-like particles.
Journal of virology 1993;67(12):6929-36.
1993: Jeffrey E DeClue; William C Vass; M R Johnson; D W Stacey; Douglas Lowy
Functional role of GTPase-activating protein in cell transformation by pp60v-src.
Molecular and cellular biology 1993;13(11):6799-809.
1993: B D Cohen; Douglas Lowy; John T Schiller
The conserved C-terminal domain of the bovine papillomavirus E5 oncoprotein can associate with an alpha-adaptin-like molecule: a possible link between growth factor receptors and viral transformation.
Molecular and cellular biology 1993;13(10):6462-8.
1993: B D Cohen; D J Goldstein; L Rutledge; William C Vass; Douglas Lowy; Richard Schlegel; John T Schiller
Transformation-specific interaction of the bovine papillomavirus E5 oncoprotein with the platelet-derived growth factor receptor transmembrane domain and the epidermal growth factor receptor cytoplasmic domain.
Journal of virology 1993;67(9):5303-11.
1993: M R Johnson; A T Look; Jeffrey E DeClue; M B Valentine; Douglas Lowy
Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5539-43.
1993: W D Ju; J T Schiller; M K Kazempour; Douglas Lowy
TGF alpha enhances locomotion of cultured human keratinocytes.
The Journal of investigative dermatology 1993;100(5):628-32.
1993: Douglas Lowy; S A Sedman; B D Cohen; John T Schiller
Human papillomaviruses and cancer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;128():351-2.
1993: Douglas Lowy; Berthe M Willumsen
Function and regulation of ras.
Annual review of biochemistry 1993;62():851-91.
1993: Douglas Lowy; M R Johnson; Jeffrey E DeClue; H Cen; K Zhang; Alex G Papageorge; William C Vass; Berthe M Willumsen; M B Valentine; A T Look
Cell transformation by ras and regulation of its protein product.
Ciba Foundation symposium 1993;176():67-80; discussion 80-4.
1992: Reinhard Kirnbauer; frank booy; Naiqian Cheng; Douglas Lowy; John T Schiller
Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):12180-4.
1992: H Cen; Alex G Papageorge; R Zippel; Douglas Lowy; K Zhang
Isolation of multiple mouse cDNAs with coding homology to Saccharomyces cerevisiae CDC25: identification of a region related to Bcr, Vav, Dbl and CDC24.
The EMBO journal 1992;11(11):4007-15.
1992: K Zhang; Alex G Papageorge; Douglas Lowy
Mechanistic aspects of signaling through Ras in NIH 3T3 cells.
Science (New York, N.Y.) 1992;257(5070):671-4.
1992: S A Sedman; N L Hubbert; William C Vass; Douglas Lowy; John T Schiller
Mutant p53 can substitute for human papillomavirus type 16 E6 in immortalization of human keratinocytes but does not have E6-associated trans-activation or transforming activity.
Journal of virology 1992;66(7):4201-8.
1992: Jeffrey E DeClue; Alex G Papageorge; J A Fletcher; S R Diehl; Nancy Ratner; William C Vass; Douglas Lowy
Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis.
Cell 1992;69(2):265-73.
1991: K Zhang; Alex G Papageorge; P Martin; William C Vass; Zoltan Olah; P G Polakis; F McCormick; Douglas Lowy
Heterogeneous amino acids in Ras and Rap1A specifying sensitivity to GAP proteins.
Science (New York, N.Y.) 1991;254(5038):1630-4.
1991: Berthe M Willumsen; William C Vass; T J Velu; Alex G Papageorge; J T Schiller; Douglas Lowy
The bovine papillomavirus E5 oncogene can cooperate with ras: identification of p21 amino acids critical for transformation by c-rasH but not v-rasH.
Molecular and cellular biology 1991;11(12):6026-33.
1991: Jeffrey E DeClue; B D Cohen; Douglas Lowy
Identification and characterization of the neurofibromatosis type 1 protein product.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):9914-8.
1991: Douglas Lowy; K Zhang; Jeffrey E DeClue; Berthe M Willumsen
Regulation of p21ras activity.
Trends in genetics : TIG 1991;7(11-12):346-51.
1991: S A Sedman; M S Barbosa; William C Vass; N L Hubbert; J A Haas; Douglas Lowy; John T Schiller
The full-length E6 protein of human papillomavirus type 16 has transforming and trans-activating activities and cooperates with E7 to immortalize keratinocytes in culture.
Journal of virology 1991;65(9):4860-6.
1991: Jeffrey E DeClue; James C Stone; R A Blanchard; Alex G Papageorge; P Martin; K Zhang; Douglas Lowy
A ras effector domain mutant which is temperature sensitive for cellular transformation: interactions with GTPase-activating protein and NF-1.
Molecular and cellular biology 1991;11(6):3132-8.
1991: Jeffrey E DeClue; K Zhang; P Redford; William C Vass; Douglas Lowy
Suppression of src transformation by overexpression of full-length GTPase-activating protein (GAP) or of the GAP C terminus.
Molecular and cellular biology 1991;11(5):2819-25.
1991: K Helin; T Velu; P Martin; William C Vass; G Allevato; Douglas Lowy; L Beguinot
The biological activity of the human epidermal growth factor receptor is positively regulated by its C-terminal tyrosines.
Oncogene 1991;6(5):825-32.
1991: W D Ju; T J Velu; William C Vass; Alex G Papageorge; Douglas Lowy
Tumorigenic transformation of NIH 3T3 cells by the autocrine synthesis of transforming growth factor alpha.
The New biologist 1991;3(4):380-8.
1991: Jeffrey E DeClue; William C Vass; Alex G Papageorge; Douglas Lowy; Berthe M Willumsen
Inhibition of cell growth by lovastatin is independent of ras function.
Cancer research 1991;51(2):712-7.
1991: M S Barbosa; William C Vass; Douglas Lowy; John T Schiller
In vitro biological activities of the E6 and E7 genes vary among human papillomaviruses of different oncogenic potential.
Journal of virology 1991;65(1):292-8.
1990: C Collin; A G Papageorge; Douglas Lowy; Daniel L Alkon
Early enhancement of calcium currents by H-ras oncoproteins injected into Hermissenda neurons.
Science (New York, N.Y.) 1990;250(4988):1743-5.
1990: B Binétruy; J Schiller; Douglas Lowy; Christa Cerni; François Cuzin
Non-selective analysis of the transformation of FR3T3 rat cells by bovine papillomavirus type 1: regulations of viral transcription associated with phenotypic transformation.
Oncogene 1990;5(11):1645-51.
1990: C Collin; A G Papageorge; Manabu Sakakibara; P L Huddie; Douglas Lowy; Daniel L Alkon
Early regulation of membrane excitability by ras oncogene proteins.
Biophysical journal 1990;58(3):785-90.
1990: K Zhang; Jeffrey E DeClue; William C Vass; Alex G Papageorge; F McCormick; Douglas Lowy
Suppression of c-ras transformation by GTPase-activating protein.
Nature 1990;346(6286):754-6.
1990: K Zhang; M Noda; William C Vass; Alex G Papageorge; Douglas Lowy
Identification of small clusters of divergent amino acids that mediate the opposing effects of ras and Krev-1.
Science (New York, N.Y.) 1990;249(4965):162-5.
1990: P S Kedar; Douglas Lowy; S G Widen; Samuel H Wilson
Transfected human beta-polymerase promoter contains a ras-responsive element.
Molecular and cellular biology 1990;10(7):3852-6.
1990: K D Cooper; E J Androphy; Douglas Lowy; Stephen I Katz
Antigen presentation and T-cell activation in epidermodysplasia verruciformis.
The Journal of investigative dermatology 1990;94(6):769-76.
1990: Ricardo A Feldman; Douglas Lowy; William C Vass
Selective potentiation of c-fps/fes transforming activity by a phosphatase inhibitor.
Oncogene research 1990;5(3):187-97.
1990: M S Barbosa; C Edmonds; C Fisher; John T Schiller; Douglas Lowy; Karen H Vousden
The region of the HPV E7 oncoprotein homologous to adenovirus E1a and Sv40 large T antigen contains separate domains for Rb binding and casein kinase II phosphorylation.
The EMBO journal 1990;9(1):153-60.
1989: Ricardo A Feldman; Douglas Lowy; William C Vass; T J Velu
A highly efficient retroviral vector allows detection of the transforming activity of the human c-fps/fes proto-oncogene.
Journal of virology 1989;63(12):5469-74.
1989: P Hawley-Nelson; Karen H Vousden; N L Hubbert; Douglas Lowy; John T Schiller
HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes.
The EMBO journal 1989;8(12):3905-10.
1989: P Martin; William C Vass; John T Schiller; Douglas Lowy; T J Velu
The bovine papillomavirus E5 transforming protein can stimulate the transforming activity of EGF and CSF-1 receptors.
Cell 1989;59(1):21-32.
1989: Douglas Lowy; B M Willumsen
Protein modification: new clue to Ras lipid glue.
Nature 1989;341(6241):384-5.
1989: W S Sawchuk; P J Weber; Douglas Lowy; L M Dzubow
Infectious papillomavirus in the vapor of warts treated with carbon dioxide laser or electrocoagulation: detection and protection.
Journal of the American Academy of Dermatology 1989;21(1):41-9.
1989: Christa Cerni; B Binétruy; John T Schiller; Douglas Lowy; G Meneguzzi; François Cuzin
Successive steps in the process of immortalization identified by transfer of separate bovine papillomavirus genes into rat fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3266-70.
1989: Karen H Vousden; E J Androphy; John T Schiller; Douglas Lowy
Mutational analysis of bovine papillomavirus E6 gene.
Journal of virology 1989;63(5):2340-2.
1989: T J Velu; William C Vass; Douglas Lowy; L Beguinot
Functional heterogeneity of proto-oncogene tyrosine kinases: the C terminus of the human epidermal growth factor receptor facilitates cell proliferation.
Molecular and cellular biology 1989;9(4):1772-8.
1989: D R Bickers; Douglas Lowy
Carcinogenesis: a fifty-year historical perspective.
The Journal of investigative dermatology 1989;92(4 Suppl):121S-131S.
1989: John T Schiller; E Kleiner; E J Androphy; Douglas Lowy; H Pfister
Identification of bovine papillomavirus E1 mutants with increased transforming and transcriptional activity.
Journal of virology 1989;63(4):1775-82.
1989: M S Barbosa; Douglas Lowy; John T Schiller
Papillomavirus polypeptides E6 and E7 are zinc-binding proteins.
Journal of virology 1989;63(3):1404-7.
1989: T J Velu; William C Vass; Douglas Lowy; P E Tambourin
Harvey murine sarcoma virus: influences of coding and noncoding sequences on cell transformation in vitro and oncogenicity in vivo.
Journal of virology 1989;63(3):1384-92.
1989: T J Velu; L Beguinot; William C Vass; K Zhang; Ira Pastan; Douglas Lowy
Retroviruses expressing different levels of the normal epidermal growth factor receptor: biological properties and new bioassay.
Journal of cellular biochemistry 1989;39(2):153-66.
1988: Karen H Vousden; Jay Doniger; Joseph A Dipaolo; Douglas Lowy
The E7 open reading frame of human papillomavirus type 16 encodes a transforming gene.
Oncogene research 1988;3(2):167-75.
1988: J C Stone; William C Vass; Berthe M Willumsen; Douglas Lowy
p21-ras effector domain mutants constructed by "cassette" mutagenesis.
Molecular and cellular biology 1988;8(8):3565-9.
1988: N L Hubbert; John T Schiller; Douglas Lowy; E J Androphy
Bovine papilloma virus-transformed cells contain multiple E2 proteins.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):5864-8.
1988: H Adari; Douglas Lowy; B M Willumsen; Channing J Der; F McCormick
Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain.
Science (New York, N.Y.) 1988;240(4851):518-21.
1988: T J Velu; Douglas Lowy
Proto-oncogene activation in lung cancer.
The New England journal of medicine 1988;318(15):992.
1988: P Hawley-Nelson; E J Androphy; Douglas Lowy; John T Schiller
The specific DNA recognition sequence of the bovine papillomavirus E2 protein is an E2-dependent enhancer.
The EMBO journal 1988;7(2):525-31.
1987: T J Velu; L Beguinot; William C Vass; M C Willingham; G T Merlino; Ira Pastan; Douglas Lowy
Epidermal-growth-factor-dependent transformation by a human EGF receptor proto-oncogene.
Science (New York, N.Y.) 1987;238(4832):1408-10.
1987: E J Androphy; N L Hubbert; John T Schiller; Douglas Lowy
Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines.
The EMBO journal 1987;6(4):989-92.
1987: Douglas Lowy
Potential oncogenic hazards posed by oncogene encoded proteins.
Developments in biological standardization 1987;68():63-7.
1987: E J Androphy; Douglas Lowy; J T Schiller
Bovine papillomavirus E2 trans-activating gene product binds to specific sites in papillomavirus DNA.
Nature 1987;325(6099):70-3.
1986: D R Roop; Douglas Lowy; P E Tambourin; J Strickland; J R Harper; M Balaschak; E F Spangler; S H Yuspa
An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue.
Nature 1986;323(6091):822-4.
1986: Berthe M Willumsen; Alex G Papageorge; H F Kung; E Bekesi; T Robins; M Johnsen; William C Vass; Douglas Lowy
Mutational analysis of a ras catalytic domain.
Molecular and cellular biology 1986;6(7):2646-54.
1986: Alex G Papageorge; Berthe M Willumsen; M Johnsen; H F Kung; D W Stacey; William C Vass; Douglas Lowy
A transforming ras gene can provide an essential function ordinarily supplied by an endogenous ras gene.
Molecular and cellular biology 1986;6(5):1843-6.
1986: A Levitzki; J Rudick; Ira Pastan; W C Vass; Douglas Lowy
Adenylate cyclase activity of NIH 3T3 cells morphologically transformed by ras genes.
FEBS letters 1986;197(1-2):134-8.
1986: Douglas Lowy; B M Willumsen
The ras gene family.
Cancer surveys 1986;5(2):275-89.
1986: J T Schiller; W C Vass; K H Vousden; Douglas Lowy
E5 open reading frame of bovine papillomavirus type 1 encodes a transforming gene.
Journal of virology 1986;57(1):1-6.
1985: Douglas Lowy
Oncogenes are here to stay.
The Journal of investigative dermatology 1985;85(6):495-7.
1985: Berthe M Willumsen; Alex G Papageorge; N Hubbert; E Bekesi; H F Kung; Douglas Lowy
Transforming p21 ras protein: flexibility in the major variable region linking the catalytic and membrane-anchoring domains.
The EMBO journal 1985;4(11):2893-6.
1985: E J Androphy; J T Schiller; Douglas Lowy
Identification of the protein encoded by the E6 transforming gene of bovine papillomavirus.
Science (New York, N.Y.) 1985;230(4724):442-5.
1985: R J Muschel; J E Williams; Douglas Lowy; L A Liotta
Harvey ras induction of metastatic potential depends upon oncogene activation and the type of recipient cell.
The American journal of pathology 1985;121(1):1-8.
1985: Douglas Lowy; John T Schiller
Papillomaviruses.
Clinics in dermatology 1985;3(4):1-7.
1985: E J Androphy; I Dvoretzky; Douglas Lowy
X-linked inheritance of epidermodysplasia verruciformis. Genetic and virologic studies of a kindred.
Archives of dermatology 1985;121(7):864-8.
1985: A Kasid; Marc Lippman; A G Papageorge; Douglas Lowy; E P Gelmann
Transfection of v-rasH DNA into MCF-7 human breast cancer cells bypasses dependence on estrogen for tumorigenicity.
Science (New York, N.Y.) 1985;228(4700):725-8.
1985: D DeFeo-Jones; K Tatchell; L C Robinson; I S Sigal; W C Vass; Douglas Lowy; E M Scolnick
Mammalian and yeast ras gene products: biological function in their heterologous systems.
Science (New York, N.Y.) 1985;228(4696):179-84.
1984: J T Schiller; W C Vass; Douglas Lowy
Identification of a second transforming region in bovine papillomavirus DNA.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(24):7880-4.
1984: W L Epstein; J C Bystryn; R Edelson; P M Elias; Douglas Lowy; S Yuspa
Nonmelanoma skin cancer, melanomas, warts, and viral oncogenesis.
Journal of the American Academy of Dermatology 1984;11(5 Pt 2):960-70.
1984: Berthe M Willumsen; K Norris; Alex G Papageorge; N L Hubbert; Douglas Lowy
Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.
The EMBO journal 1984;3(11):2581-5.
1984: Berthe M Willumsen; A Christensen; N L Hubbert; Alex G Papageorge; Douglas Lowy
The p21 ras C-terminus is required for transformation and membrane association.
Nature 1984;310(5978):583-6.
1984: E J Androphy; I Dvoretzky; A E Maluish; H J Wallace; Douglas Lowy
Response of warts in epidermodysplasia verruciformis to treatment with systemic and intralesional alpha interferon.
Journal of the American Academy of Dermatology 1984;11(2 Pt 1):197-202.
1984: Y Nakabayashi; I Dvoretzky; S K Chattopadhyay; Douglas Lowy
In vitro transformation by bovine papillomavirus.
The Journal of investigative dermatology 1984;83(1 Suppl):12s-17s.
1984: B M Willumsen; R W Ellis; E M Scolnick; Douglas Lowy
Further genetic localization of the transforming sequences of the p21 v-ras gene of Harvey murine sarcoma virus.
Journal of virology 1984;49(2):601-3.
1984: E J Androphy; Douglas Lowy
Tumor viruses, oncogenes, and human cancer.
Journal of the American Academy of Dermatology 1984;10(1):125-41.
1983: Y Nakabayashi; S K Chattopadhyay; Douglas Lowy
The transforming function of bovine papillomavirus DNA.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(19):5832-6.
1983: S J O'Brien; W G Nash; J L Goodwin; Douglas Lowy; E H Chang
Dispersion of the ras family of transforming genes to four different chromosomes in man.
Nature 1983;302(5911):839-42.
1983: L D Smyth; Douglas Lowy
Auditory vigilance during hypnosis: a brief communication.
The International journal of clinical and experimental hypnosis 1983;31(2):67-71.
1983: M S McCoy; J J Toole; J M Cunningham; E H Chang; Douglas Lowy; Robert A. Weinberg
Characterization of a human colon/lung carcinoma oncogene.
Nature 1983;302(5903):79-81.
1983: J Even; S J Anderson; A Hampe; F Galibert; Douglas Lowy; G Khoury; C J Sherr
Mutant feline sarcoma proviruses containing the viral oncogene (v-fes) and either feline or murine control elements.
Journal of virology 1983;45(3):1004-16.
1983: M Kelly; C A Holland; M L Lung; S K Chattopadhyay; Douglas Lowy; N H Hopkins
Nucleotide sequence of the 3' end of MCF 247 murine leukemia virus.
Journal of virology 1983;45(1):291-8.
1982: L P Turek; J C Byrne; Douglas Lowy; I Dvoretzky; R M Friedman; Peter M Howley
Interferon induces morphologic reversion with elimination of extrachromosomal viral genomes in bovine papillomavirus-transformed mouse cells.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(24):7914-8.
1982: C J Tabin; S M Bradley; C I Bargmann; Robert A. Weinberg; A G Papageorge; E M Scolnick; R Dhar; Douglas Lowy; E H Chang
Mechanism of activation of a human oncogene.
Nature 1982;300(5888):143-9.
1982: A Papageorge; Douglas Lowy; E M Scolnick
Comparative biochemical properties of p21 ras molecules coded for by viral and cellular ras genes.
Journal of virology 1982;44(2):509-19.
1982: R Dhar; R W Ellis; T Y Shih; S Oroszlan; B Shapiro; J Maizel; Douglas Lowy; E Scolnick
Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus.
Science (New York, N.Y.) 1982;217(4563):934-6.
1982: E H Chang; M A Gonda; R W Ellis; E M Scolnick; Douglas Lowy
Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(16):4848-52.
1982: E H Chang; Mark E Furth; E M Scolnick; Douglas Lowy
Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus.
Nature 1982;297(5866):479-83.
1982: Carole Heilman; L Engel; Douglas Lowy; Peter M Howley
Virus-specific transcription in bovine papillomavirus-transformed mouse cells.
Virology 1982;119(1):22-34.
1982: S K Chattopadhyay; E H Chang; M R Lander; R W Ellis; E M Scolnick; Douglas Lowy
Amplification and rearrangement of onc genes in mammalian species.
Nature 1982;296(5855):361-3.
1982: I Dvoretzky; Douglas Lowy
Infections by human papillomavirus (warts).
The American Journal of dermatopathology 1982;4(1):85-9.
1982: Alan Rein; Douglas Lowy; B I Gerwin; S K Ruscetti; R H Bassin
Molecular properties of a gag- pol- env+ murine leukemia virus from cultured AKR lymphoma cells.
Journal of virology 1982;41(2):626-34.
1982: C Van Beveren; E Rands; S K Chattopadhyay; Douglas Lowy; Inder M Verma
Long terminal repeat of murine retroviral DNAs: sequence analysis, host-proviral junctions, and preintegration site.
Journal of virology 1982;41(2):542-56.
1982: S K Chattopadhyay; M W Cloyd; David Linemeyer; M R Lander; E Rands; Douglas Lowy
Cellular origin and role of mink cell focus-forming viruses in murine thymic lymphomas.
Nature 1982;295(5844):25-31.
1981: S K Chattopadhyay; A I Oliff; David Linemeyer; M R Lander; Douglas Lowy
Genomes of murine leukemia viruses isolated from wild mice.
Journal of virology 1981;39(3):777-91.
1981: S K Chattopadhyay; M R Lander; S Gupta; E Rands; Douglas Lowy
Origin of mink cytopathic focus-forming (MCF) viruses:comparison with ecotropic and xenotropic murine leukemia virus genomes.
Virology 1981;113(2):465-83.
1981: R W Ellis; D Defeo; T Y Shih; M A Gonda; H A Young; N Tsuchida; Douglas Lowy; E M Scolnick
The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes.
Nature 1981;292(5823):506-11.
1981: D DeFeo; M A Gonda; H A Young; E H Chang; Douglas Lowy; E M Scolnick; R W Ellis
Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(6):3328-32.
1981: M F Law; Douglas Lowy; I Dvoretzky; Peter M Howley
Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(5):2727-31.
1981: E Rands; Douglas Lowy; M R Lander; S K Chattopadhyay
Restriction endonuclease mapping of ecotropic murine leukemia viral DNAs: size and sequence heterogeneity of the long terminal repeat.
Virology 1981;108(2):445-52.
1980: E H Chang; R W Ellis; E M Scolnick; Douglas Lowy
Transformation by cloned Harvey murine sarcoma virus DNA: efficiency increased by long terminal repeat DNA.
Science (New York, N.Y.) 1980;210(4475):1249-51.
1980: R W Ellis; D DeFeo; J M Maryak; H A Young; T Y Shih; E H Chang; Douglas Lowy; E M Scolnick
Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus.
Journal of virology 1980;36(2):408-20.
1980: S K Chattopadhyay; M R Lander; E Rands; Douglas Lowy
Structure of endogenous murine leukemia virus DNA in mouse genomes.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(10):5774-8.
1980: Douglas Lowy; I Dvoretzky; R Shober; M F Law; L Engel; Peter M Howley
In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA.
Nature 1980;287(5777):72-4.
1980: A Oliff; D Linemeyer; S Ruscetti; R Lowe; Douglas Lowy; E Scolnick
Subgenomic fragment of molecular cloned Friend murine leukemia virus DNA contains the gene(s) responsible for Friend murine leukemia virus-induced disease.
Journal of virology 1980;35(3):924-36.
1980: C M Wei; Douglas Lowy; E M Scolnick
Mapping of transforming region of the Harvey murine sarcoma virus genome by using insertion-deletion mutants constructed in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(8):4674-8.
1980: E H Chang; J M Maryak; C M Wei; T Y Shih; R Shober; H L Cheung; R W Ellis; G L Hager; E M Scolnick; Douglas Lowy
Functional organization of the Harvey murine sarcoma virus genome.
Journal of virology 1980;35(1):76-92.
1980: I Dvoretzky; R Shober; S K Chattopadhyay; Douglas Lowy
A quantitative in vitro focus assay for bovine papilloma virus.
Virology 1980;103(2):369-75.
1980: H W Chang; C F Garon; E H Chang; Douglas Lowy; G L Hager; E M Scolnick; R Repaske; Malcolm Martin
Molecular cloning of the Harvey sarcoma virus circular DNA intermediates. II. Further structural analyses.
Journal of virology 1980;33(2):845-55.
1980: E M Scolnick; T Y Shih; J Maryak; R Ellis; E Chang; Douglas Lowy
Guanine nucleotide binding activity of the src gene product of rat-derived murine sarcoma viruses.
Annals of the New York Academy of Sciences 1980;354():398-409.
1980: Douglas Lowy; E Rands; S K Chattopadhyay; G L Hager
Structure and infectivity of integrated murine leukemia virus DNA.
Cold Spring Harbor symposia on quantitative biology 1980;44 Pt 2,():1143-51.
1980: A I Oliff; G L Hager; E H Chang; E M Scolnick; H W Chan; Douglas Lowy
Transfection of molecularly cloned Friend murine leukemia virus DNA yields a highly leukemogenic helper-independent type C virus.
Journal of virology 1980;33(1):475-86.
1980: Douglas Lowy; E Rands; S K Chattopadhyay; C F Garon; G L Hager
Molecular cloning of infectious integrated murine leukemia virus DNA from infected mouse cells.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(1):614-8.
1979: G L Hager; E H Chang; H W Chan; C F Garon; Mark Israel; Malcolm Martin; E M Scolnick; Douglas Lowy
Molecular cloning of the Harvey sarcoma virus closed circular DNA intermediates: initial structural and biological characterization.
Journal of virology 1979;31(3):795-809.
1978: Douglas Lowy
Infectious murine leukemia virus from DNA of virus-negative AKR mouse embryo cells.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(11):5539-43.
1978: Douglas Lowy; E Rands; E M Scolnick
Helper-independent transformation by unintegrated Harvey sarcoma virus DNA.
Journal of virology 1978;26(2):291-8.
1978: Douglas Lowy; E M Scolnick
Glucocorticoids induce focus formation and increase sarcoma viral expression in a mink cell line that contains a murine sarcoma viral genome.
Journal of virology 1978;25(1):157-63.
1978: R S Howk; D H Troxler; Douglas Lowy; P H Duesberg; E M Scolnick
Identification of a 30S RNA with properties of a defective type C virus in murine cells.
Journal of virology 1978;25(1):115-23.
1977: N M Teich; R A Weiss; G R Martin; Douglas Lowy
Virus infection of murine teratocarcinoma stem cell lines.
Cell 1977;12(4):973-82.
1977: D H Troxler; Douglas Lowy; R Howk; H Young; E M Scolnick
Friend strain of spleen focus-forming virus is a recombinant between ecotropic murine type C virus and the env gene region of xenotropic type C virus.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(10):4671-5.
1975: S K Chattopadhyay; W P Rowe; N M Teich; Douglas Lowy
Definitive evidence that the murine C-type virus inducing locus Akv-1 is viral genetic material.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(3):906-10.
1975: S K Chattopadhyay; Douglas Lowy; N M Teich; A S Levine; W P Rowe
Qualitative and quantitative studies of AKR-type murine leukemia virus sequences in mouse DNA.
Cold Spring Harbor symposia on quantitative biology 1975;39 Pt 2():1085-101.
1974: Douglas Lowy; N M Teich; S K Chattopadhyay
Expression and detection of endogenous mouse C-type RNA viruses.
In vitro 1974;10(5-6):253-9.
1974: Douglas Lowy; S K Chattopadhyay; N M Teich; W P Rowe; A S Levine
AKR murine leukemia virus genome: frequency of sequences in DNA of high-, low-, and non-virus-yielding mouse strains.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(9):3555-9.
1974: S K Chattopadhyay; Douglas Lowy; N M Teich; A S Levine; W P Rowe
Evidence that the AKR murine-leukemia-virus genome is complete in DNA of the high-virus AKR mouse and incomplete in the DNA of the "virus-negative" NIH mouse.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(1):167-71.
1973: PAULA PITHA-ROWE; N M Teich; Douglas Lowy; J Pitha
Inhibition of murine leukemia virus replication by poly(vinyluracil) and poly(vinyladenine).
Proceedings of the National Academy of Sciences of the United States of America 1973;70(4):1204-8.
1973: N Teich; Douglas Lowy; J W Hartley; W P Rowe
Studies of the mechanism of induction of infectious murine leukemia virus from AKR mouse embryo cell lines by 5-iododeoxyuridine and 5-bromodeoxyuridine.
Virology 1973;51(1):163-73.
1972: Douglas Lowy; L Lowy; R S Warner
A survey of physicians' awareness of drug costs.
Journal of medical education 1972;47(5):349-51.
1972: W P Rowe; Douglas Lowy; N Teich; J W Hartley
Some implications of the activation of murine leukemia virus by halogenated pyrimidines.
Proceedings of the National Academy of Sciences of the United States of America 1972;69(4):1033-5.
1971: Douglas Lowy; W P Rowe; N Teich; J W Hartley
Murine leukemia virus: high-frequency activation in vitro by 5-iododeoxyuridine and 5-bromodeoxyuridine.
Science (New York, N.Y.) 1971;174(4005):155-6.
1967: J Vilcek; Douglas Lowy
Interaction of interferon with chick embryo cells.
Archiv für die gesamte Virusforschung 1967;21(2):253-64.