FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Gary Nabel

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Co-author Network

Publications

TOP 3
Kylie M Quinn; Mario Roederer; Lingshu Wang; Linda S Wyatt; Ayako Yamamoto; Robert T Bailer; Dana Berry; Cheng Cheng; Stefano Colloca; Riccardo Cortese; Andreia Da Costa; Patricia A Darrah; Mariano Esteban; Antonella Folgori; Jason G D Gall; Carmen E Gomez; Emma Gostick; Wing-Pui Kong; Richard A Koup; Ross W B Lindsay; Cecilia Morgan; Bernard Moss; Gary Nabel; Alfredo Nicosia; David A Price; Robert A Seder
Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization.
Gary Nabel
Designing tomorrow's vaccines.
M Gordon Joyce; Masaru Kanekiyo; Peter D Kwong; John R Mascola; Stephanie Moquin; Christian Biertümpfel; Jeffrey C Boyington; Wei Shi; Xueling Wu; Ling Xu; Yongping Yang; Zhi-Yong Yang; Baoshan Zhang; Anqi Zheng; Tongqing Zhou; Jiang Zhu; Gary Nabel
Outer domain of HIV-1 gp120: antigenic optimization, structural malleability, and crystal structure with antibody VRC-PG04.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Gary Nabel (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Kylie M Quinn; Mario Roederer; Lingshu Wang; Linda S Wyatt; Ayako Yamamoto; Robert T Bailer; Dana Berry; Cheng Cheng; Stefano Colloca; Riccardo Cortese; Andreia Da Costa; Patricia A Darrah; Mariano Esteban; Antonella Folgori; Jason G D Gall; Carmen E Gomez; Emma Gostick; Wing-Pui Kong; Richard A Koup; Ross W B Lindsay; Cecilia Morgan; Bernard Moss; Gary Nabel; Alfredo Nicosia; David A Price; Robert A Seder
Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(6):2720-35.
2013: Gary Nabel
Designing tomorrow's vaccines.
The New England journal of medicine 2013;368(6):551-60.
2013: M Gordon Joyce; Masaru Kanekiyo; Peter D Kwong; John R Mascola; Stephanie Moquin; Christian Biertümpfel; Jeffrey C Boyington; Wei Shi; Xueling Wu; Ling Xu; Yongping Yang; Zhi-Yong Yang; Baoshan Zhang; Anqi Zheng; Tongqing Zhou; Jiang Zhu; Gary Nabel
Outer domain of HIV-1 gp120: antigenic optimization, structural malleability, and crystal structure with antibody VRC-PG04.
Journal of virology 2013;87(4):2294-306.
2013: Barney S Graham; Richard A Koup; Julie E Ledgerwood; John R Mascola; Gary Nabel; Martha C Nason; Sheila A Peel; Sarah A Plummer; Mario Roederer; Robert T Bailer; Mary E Enama; Ingelise J Gordon
DNA vaccine delivered by a needle-free injection device improves potency of priming for antibody and CD8+ T-cell responses after rAd5 boost in a randomized clinical trial.
PloS one 2013;8(4):e59340.
2012: Will Fischer; Rajeev Gautam; Beatrice H Hahn; Norman L Letvin; Yingying Li; Gary Nabel; Ivona Pandrea; Mario L Santiago; George M Shaw; Cristian Apetrei; Bette T Korber
Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages.
Journal of virology 2012;86(24):13217-31.
2012: J E Ledgerwood; John R Mascola; Gary Nabel; M B Pearce; S Plummer; T M Tumpey; G Yamshchikov; Robert T Bailer; Mary E Enama; I J Gordon; Barney S Graham; Z Hu; Richard A Koup
Influenza virus h5 DNA vaccination is immunogenic by intramuscular and intradermal routes in humans.
Clinical and vaccine immunology : CVI 2012;19(11):1792-7.
2012: Daniel Lingwood; Patrick M McTamney; Jeffrey C Boyington; Xiaoti Guo; Chih-Jen Wei; James R R Whittle; Hadi M Yassine; Gary Nabel
Structural and genetic basis for development of broadly neutralizing influenza antibodies.
Nature 2012;489(7417):566-70.
2012: Gwo-Yu Chuang; Jeffrey C Boyington; M Gordon Joyce; Peter D Kwong; Gary Nabel; Jiang Zhu; Ivelin Georgiev
Computational prediction of N-linked glycosylation incorporating structural properties and patterns.
Bioinformatics (Oxford, England) 2012;28(17):2249-55.
2012: Chih-Jen Wei; James R R Whittle; Hadi M Yassine; Jeffrey C Boyington; Jason G D Gall; Patrick M McTamney; Gary Nabel
Elicitation of broadly neutralizing influenza antibodies in animals with previous influenza exposure.
Science translational medicine 2012;4(147):147ra114.
2012: Adjoa Smalls-Mantey; Hing Wong; Lijing You; Nicole Doria-Rose; Claire W Hallahan; John C Kappes; Rachel Klein; Sung-Youl Ko; Bai Liu; John R Mascola; Stephen A Migueles; Gary Nabel; Christina Ochsenbauer; Andy Patamawenu; Johannes Scheid; Mark Connors
Antibody-dependent cellular cytotoxicity against primary HIV-infected CD4+ T cells is directly associated with the magnitude of surface IgG binding.
Journal of virology 2012;86(16):8672-80.
2012: Christopher D O'Donnell; Leatrice N Vogel; Chih-Jen Wei; Amber Wright; Gary Nabel; Kanta Subbarao
Effect of priming with H1N1 influenza viruses of variable antigenic distances on challenge with 2009 pandemic H1N1 virus.
Journal of virology 2012;86(16):8625-33.
2012: Wataru Akahata; Gary Nabel
A specific domain of the Chikungunya virus E2 protein regulates particle formation in human cells: implications for alphavirus vaccine design.
Journal of virology 2012;86(16):8879-83.
2012: Lukas Flatz; Kathryn E Foulds; Jason G D Gall; Sung-Youl Ko; Wing-Pui Kong; Norman L Letvin; John R Mascola; Daniel D Pinschewer; SRINIVAS RAO; Mario Roederer; Rahul Roychoudhuri; Stephen D Schmidt; Ling Shen; Wei Shi; John-Paul Todd; Lingshu Wang; Mohammed Asmal; Saran Bao; Cheng Cheng; Mitzi Donaldson; Gary Nabel
Gene-based vaccination with a mismatched envelope protects against simian immunodeficiency virus infection in nonhuman primates.
Journal of virology 2012;86(15):7760-70.
2012: Sampa Santra; Sydeaka Watson; Zhi-Yong Yang; Harikrishnan Balachandran; Adam P Buzby; Kevin R Carlson; Wing-Pui Kong; Bette T Korber; Linh Mach; John R Mascola; Krisha McKee; Mark Muldoon; Gary Nabel; SRINIVAS RAO; Norman L Letvin
Breadth of cellular and humoral immune responses elicited in rhesus monkeys by multi-valent mosaic and consensus immunogens.
Virology 2012;428(2):121-7.
2012: Rebecca M Lynch; Salim Abdool Karim; Myron Cohen; Rebecca DerSimonian; Zelda Euler; Elin S Gray; Barton F Haynes; Jennifer Kirchherr; Mark K Louder; David C Montefiori; Lynn Morris; Gary Nabel; Stephen D Schmidt; Hanneke Schuitemaker; Sengeziwe Sibeko; Kelly Soderberg; Georgia D Tomaras; Lillian Tran; Zhi-Yong Yang; John R Mascola
The development of CD4 binding site antibodies during HIV-1 infection.
Journal of virology 2012;86(14):7588-95.
2012: Wendy W Yeh; Jinrong Zhang; Aravind Basavapathruni; Laura M Brassard; Norman L Letvin; John R Mascola; Caroline A Miller; Gary Nabel; SRINIVAS RAO; Michael S Seaman
Envelope variable region 4 is the first target of neutralizing antibodies in early simian immunodeficiency virus mac251 infection of rhesus monkeys.
Journal of virology 2012;86(13):7052-9.
2012: Gary Nabel; Steven M Wolinsky; Barton F Haynes
Retrospective. Norman L. Letvin (1949-2012).
Science (New York, N.Y.) 2012;336(6089):1653.
2012: Kevin O Saunders; Rebecca S Rudicell; Gary Nabel
The design and evaluation of HIV-1 vaccines.
AIDS (London, England) 2012;26(10):1293-302.
2012: Alida Ault; Udeni B R Balasuriya; Saran Bao; Thomas M Chambers; Jennifer Donofrio-Newman; J Patrick Gorres; David W Horohov; Wing-Pui Kong; Gary Nabel; Allen E Page; Stephanie E Reedy; Michael Royals; Tracy L Sturgill; Chih-Jen Wei; Zhi-Yong Yang; Alyse M Zajac; Amanda A Adams; SRINIVAS RAO
Immunogenicity and clinical protection against equine influenza by DNA vaccination of ponies.
Vaccine 2012;30(26):3965-74.
2012: Takuya Yamamoto; Wendy W Yeh; Jorge R Almeida; Daniel C Douek; Elias K Haddad; Matthew J Johnson; Francois Lefebvre; Norman L Letvin; Adrian B McDermott; Gary Nabel; Martha Nason; Constantinos Petrovas; David A Price; SRINIVAS RAO; Mario Roederer; Ling Shen; David I Wolinsky; Richard A Koup
Virus inhibition activity of effector memory CD8(+) T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection.
Journal of virology 2012;86(10):5877-84.
2012: Mayra García; Daniel Kalman; William Bornmann; Ricardo Carrion; Arik Cooper; Wei Shi; Gary Nabel
Productive replication of Ebola virus is regulated by the c-Abl1 tyrosine kinase.
Science translational medicine 2012;4(123):123ra24.
2012: Gary Nabel
Rational design of vaccines for AIDS and influenza.
Transactions of the American Clinical and Climatological Association 2012;123():9-15; discussion 15-6.
2012: Peter D Kwong; John R Mascola; Gary Nabel
The changing face of HIV vaccine research.
Journal of the International AIDS Society 2012;15(2):17407.
2012: Cheng Cheng; Lawrence Corey; Steven C DeRosa; Jason G D Gall; John Hural; M Juliana McElrath; Martha Nason; Richard M Schwartz; Lingshu Wang; LingShu Wang; Susan P Buchbinder; Gary Nabel
Decreased pre-existing Ad5 capsid and Ad35 neutralizing antibodies increase HIV-1 infection risk in the Step trial independent of vaccination.
PloS one 2012;7(4):e33969.
2011: Jason S McLellan; Zhi-Yong Yang; Mark K Louder; Jason Gorman; Doyung Lee; Stephen D Schmidt; John A Crump; John R Mascola; Tongqing Zhou; Kaifan Dai; Andrew B Ward; Sanjay Phogat; Lai-Xi Wang; Syed Shahzad-ul-Hussan; Robert Louder; Jean-Philippe Julien; Mattia Bonsignori; Wayne C Koff; Robert Pejchal; Noel E Sam; Richard Wyatt; Marie Pancera; Jared Orwenyo; Reza Khayat; Carole A Bewley; Mallika Sastry; Laura M Walker; Chris Carrico; Baoshan Zhang; Ivelin Georgiev; Stephanie Moquin; Gwo-Yu Chuang; Young Do Kwon; James Arthos; Devan Diwanji; Sijy O'Dell; Yongping Yang; Ian A Wilson; Saidi H Kapiga; Dennis R Burton; Jiang Zhu; Gary Nabel; William R Schief; Jeffrey C Boyington; Nikita Patel; Barton F Haynes; Peter D Kwong
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature 2011;480(7377):336-43.
2011: Julie E Ledgerwood; Ingelise J Gordon; Barney S Graham; John R Mascola; Robert Bailer; Chih-Jen Wei; Mary E Enama; Melissa B Pearce; Cynthia S Hendel; Gary Nabel; Terrence M Tumpey; Richard A Koup; Patrick M McTamney; Jeffrey C Boyington; Hadi M Yassine; Zonghui Hu
DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials.
The Lancet infectious diseases 2011;11(12):916-24.
2011: Jeffrey I Cohen; Anthony S Fauci; Harold Varmus; Gary Nabel
Epstein-Barr virus: an important vaccine target for cancer prevention.
Science translational medicine 2011;3(107):107fs7.
2011: J Patrick Gorres; Bruce H Janke; Marcus E Kehrli; Wing-Pui Kong; Kelly M Lager; Crystal L Loving; Gary Nabel; Michael Royals; John-Paul Todd; Amy L Vincent; Chih-Jen Wei; Eraldo L Zanella; SRINIVAS RAO
DNA vaccination elicits protective immune responses against pandemic and classic swine influenza viruses in pigs.
Clinical and vaccine immunology : CVI 2011;18(11):1987-95.
2011: Gary Nabel; Peter D Kwong; John R Mascola
Progress in the rational design of an AIDS vaccine.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2011;366(1579):2759-65.
2011: Mattia Bonsignori; Xi Chen; John A Crump; Elin Gray; S Munir Alam; Kwan-Ki Hwang; Saidi H Kapiga; Garnett Kelsoe; Thomas B Kepler; Peter D Kwong; Hua-Xin Liao; Dawn J Marshall; John R Mascola; David C Montefiori; M Anthony Moody; Lynn Morris; Gary Nabel; Sijy O'Dell; Marie Pancera; Sanjay Phogat; Noel E Sam; Michael S Seaman; George M Shaw; Faruk Sinangil; Joseph Sodroski; Georgia D Tomaras; Chun-Yen Tsao; John F Whitesides; Lan Wu; Xinzhen Yang; Yang Yongping; Baoshan Zhang; Jiang Zhu; Barton F Haynes
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors.
Journal of virology 2011;85(19):9998-10009.
2011: Wendy W Yeh; Jinrong Zhang; Laura M Brassard; Adam P Buzby; Alan Dodson; Peter T Hraber; Bette T Korber; So-Yon Lim; Corinne Luedemann; John R Mascola; Gary Nabel; SRINIVAS RAO; Ling Shen; John Paul Todd; James B Whitney; Norman L Letvin
The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys.
Journal of virology 2011;85(19):10389-98.
2011: Xueling Wu; Yongping Yang; Zhongjia Yang; Zhi-Yong Yang; Baoshan Zhang; Zhenhai Zhang; Tongqing Zhou; Jiang Zhu; Mattia Bonsignori; Dennis R Burton; Xuejun Chen; Mark Connors; John A Crump; Nicole A Doria-Rose; Ivelin Georgiev; Barton F Haynes; Saidi H Kapiga; Wayne C Koff; Peter D Kwong; Nancy S Longo; Mark Louder; Krisha McKee; James C Mullikin; Gary Nabel; Sijy O'Dell; Stephen Perfetto; Mario Roederer; Noel E Sam; Stephen D Schmidt; Lawrence Shapiro; Wei Shi; Melissa Simek; Charlene Wang; Lan Wu; John R Mascola
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
Science (New York, N.Y.) 2011;333(6049):1593-602.
2011: Stephen C De Rosa; Allan deCamp; Barney S Graham; Yunda Huang; Spyros A Kalams; Chuen-Yen Lau; M Juliana McElrath; Cecilia Morgan; Gary Nabel; Evan P Thomas; Georgia D Tomaras; Rafi Ahmed; Rama Akondy; John Bui
HIV-DNA priming alters T cell responses to HIV-adenovirus vaccine even when responses to DNA are undetectable.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(6):3391-401.
2011: Peter D Kwong; John R Mascola; Gary Nabel
Rational design of vaccines to elicit broadly neutralizing antibodies to HIV-1.
Cold Spring Harbor perspectives in medicine 2011;1(1):a007278.
2011: Nancy J Sullivan; Gene Garrard Olinger; SRINIVAS RAO; Keith A Reimann; Mario Roederer; Daphne Stanley; Clement Asiedu; Michael Bailey; Saran Bao; Joan B Geisbert; Thomas W Geisbert; Lisa E Hensley; Anna N Honko; Peter B Jahrling; Joshua Johnson; Richard A Koup; Gary Nabel
CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates.
Nature medicine 2011;17(9):1128-31.
2011: Mallika Sastry; Ling Xu; Carole A Bewley; Ivelin S Georgiev; Gary Nabel; Peter D Kwong
Mammalian production of an isotopically enriched outer domain of the HIV-1 gp120 glycoprotein for NMR spectroscopy.
Journal of biomolecular NMR 2011;50(3):197-207.
2011: Julie E Ledgerwood; Theodore C Pierson; Sarah A Hubka; Niraj Desai; Steve Rucker; Ingelise J Gordon; Mary E Enama; Steevenson Nelson; Martha Nason; Wenjuan Gu; Nikkida Bundrant; Richard A Koup; Robert T Bailer; John R Mascola; Gary Nabel; Barney S Graham
A West Nile virus DNA vaccine utilizing a modified promoter induces neutralizing antibody in younger and older healthy adults in a phase I clinical trial.
The Journal of infectious diseases 2011;203(10):1396-404.
2011: Norman L Letvin; SRINIVAS RAO; David C Montefiori; Michael S Seaman; Yue Sun; So-Yon Lim; Wendy W Yeh; Mohammed Asmal; Rebecca S Gelman; Ling Shen; James B Whitney; Cathal Seoighe; Miguel Lacerda; Sheila Keating; Philip J Norris; Michael G Hudgens; Peter B Gilbert; Adam P Buzby; Linh V Mach; Jinrong Zhang; Harikrishnan Balachandran; George M Shaw; Stephen D Schmidt; John-Paul Todd; Alan Dodson; John R Mascola; Gary Nabel
Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys.
Science translational medicine 2011;3(81):81ra36.
2011: Lawrence Corey; Gary Nabel; Carl Dieffenbach; Peter Gilbert; Barton F Haynes; Margaret Johnston; James Kublin; H Clifford Lane; Giuseppe Pantaleo; Louis J Picker; Anthony S Fauci
HIV-1 vaccines and adaptive trial designs.
Science translational medicine 2011;3(79):79ps13.
2011: Lukas Flatz; Rahul Roychoudhuri; Mitsuo Honda; Abdelali Filali-Mouhim; Jean-Philippe Goulet; Nadia Kettaf; Min Lin; Mario Roederer; Elias K Haddad; Rafick P Sékaly; Gary Nabel
Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(14):5724-9.
2011: Gary Nabel; Chih-Jen Wei; Julie E Ledgerwood
Vaccinate for the next H2N2 pandemic now.
Nature 2011;471(7337):157-8.
2011: James B Whitney; Peter T Hraber; Corinne Luedemann; Elena E Giorgi; Marcus G Daniels; Tanmoy Bhattacharya; SRINIVAS RAO; John R Mascola; Gary Nabel; Bette T Korber; Norman L Letvin
Genital tract sequestration of SIV following acute infection.
PLoS pathogens 2011;7(2):e1001293.
2011: Gavin J Churchyard; Lawrence Corey; Stephen C De Rosa; Olivier Defawe; Raphael Dolin; J Peter Figueroa; Paul Goepfert; Barney S Graham; Glenda Gray; Doug Grove; John Hural; Spyros Kalams; Artur Kalichman; Michael C Keefer; Michelle Lally; M Juliana McElrath; David C Montefiori; Zoe Moodie; Cecilia Morgan; Gary Nabel; Jean Pape; Mauro Schechter; Georgia D Tomaras; Elizabeth Adams; Lindsey R Baden; Linda-Gail Bekker; William A Blattner
A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204).
PloS one 2011;6(8):e21225.
2011: Daniel C Douek; Gary Nabel
Vaccines.
Immunological reviews 2011;239(1):5-7.
2010: Kaimei Song; Diane L Bolton; Chih-Jen Wei; Robert L Wilson; Jeremy V Camp; Saran Bao; Joseph J Mattapallil; Leonore A Herzenberg; Leonard A Herzenberg; Charla A Andrews; Jerald C Sadoff; Jaap Goudsmit; Maria G Pau; Robert A Seder; Pamela A Kozlowski; Gary Nabel; Mario Roederer; SRINIVAS RAO
Genetic immunization in the lung induces potent local and systemic immune responses.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(51):22213-8.
2010: J E Ledgerwood; P Costner; N Desai; L Holman; Mary E Enama; G Yamshchikov; S Mulangu; Z Hu; Charla A Andrews; R A Sheets; Richard A Koup; Mario Roederer; Robert T Bailer; John R Mascola; Maria G Pau; Nancy J Sullivan; Jaap Goudsmit; Gary Nabel; Barney S Graham
A replication defective recombinant Ad5 vaccine expressing Ebola virus GP is safe and immunogenic in healthy adults.
Vaccine 2010;29(2):304-13.
2010: Gary Nabel; Anthony S Fauci
Induction of unnatural immunity: prospects for a broadly protective universal influenza vaccine.
Nature medicine 2010;16(12):1389-91.
2010: Yue Sun; Sampa Santra; Adam P Buzby; John R Mascola; Gary Nabel; Norman L Letvin
Recombinant vector-induced HIV/SIV-specific CD4+ T lymphocyte responses in rhesus monkeys.
Virology 2010;406(1):48-55.
2010: Chih-Jen Wei; Jeffrey C Boyington; Patrick M McTamney; Wing-Pui Kong; Melissa B Pearce; Ling Xu; Hanne Andersen; SRINIVAS RAO; Terrence M Tumpey; Zhi-Yong Yang; Gary Nabel
Induction of broadly neutralizing H1N1 influenza antibodies by vaccination.
Science (New York, N.Y.) 2010;329(5995):1060-4.
2010: Xueling Wu; Zhi-Yong Yang; Yuxing Li; Carl-Magnus Hogerkorp; William R Schief; Michael S Seaman; Tongqing Zhou; Stephen D Schmidt; Lan Wu; Ling Xu; Nancy S Longo; Krisha McKee; Sijy O'Dell; Mark K Louder; Diane L Wycuff; Yu Feng; Martha Nason; Nicole Doria-Rose; Mark Connors; Peter D Kwong; Mario Roederer; Richard Wyatt; Gary Nabel; John R Mascola
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1.
Science (New York, N.Y.) 2010;329(5993):856-61.
2010: Tongqing Zhou; Ivelin Georgiev; Xueling Wu; Zhi-Yong Yang; Kaifan Dai; Andrés Finzi; Young Do Kwon; Johannes F Scheid; Wei Shi; Ling Xu; Yongping Yang; Jiang Zhu; Michel C Nussenzweig; Joseph Sodroski; Lawrence Shapiro; Gary Nabel; John R Mascola; Peter D Kwong
Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.
Science (New York, N.Y.) 2010;329(5993):811-7.
2010: Chih-Jen Wei; Jeffrey C Boyington; Kaifan Dai; Katherine V Houser; Melissa B Pearce; Wing-Pui Kong; Zhi-Yong Yang; Terrence M Tumpey; Gary Nabel
Cross-neutralization of 1918 and 2009 influenza viruses: role of glycans in viral evolution and vaccine design.
Science translational medicine 2010;2(24):24ra21.
2010: Lukas Flatz; Ahmed N Hegazy; Andreas Bergthaler; Admar Verschoor; Christina Claus; Marylise Fernandez; Luca Gattinoni; Susan Johnson; Florian Kreppel; Stefan Kochanek; Maries van den Broek; Andreas Radbruch; Frédéric Lévy; Paul-Henri Lambert; Claire-Anne Siegrist; Nicholas P Restifo; Max Löhning; Adrian F Ochsenbein; Gary Nabel; Daniel D Pinschewer
Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity.
Nature medicine 2010;16(3):339-45.
2010: Wataru Akahata; Zhi-Yong Yang; Hanne Andersen; Siyang Sun; Heather A Holdaway; Wing-Pui Kong; Mark G Lewis; Stephen Higgs; Michael G Rossmann; SRINIVAS RAO; Gary Nabel
A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection.
Nature medicine 2010;16(3):334-8.
2010: Chantelle Ahlenstiel; Jonathan Abraham; Jeffrey C Boyington; Kwanyee Leung; Peter D Kwong; Gary Nabel
Biochemical and structural characterization of cathepsin L-processed Ebola virus glycoprotein: implications for viral entry and immunogenicity.
Journal of virology 2010;84(6):2972-82.
2010: Gilad Ofek; Krisha McKee; Yongping Yang; Zhi-Yong Yang; Jeff Skinner; F Javier Guenaga; Richard Wyatt; Michael B Zwick; Gary Nabel; John R Mascola; Peter D Kwong
Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region.
Journal of virology 2010;84(6):2955-62.
2010: Duncan McVey; Mohammed Zuber; Damodar Ettyreddy; Christopher D Reiter; Douglas E Brough; Gary Nabel; C Richter King; Jason G D Gall
Characterization of human adenovirus 35 and derivation of complex vectors.
Virology journal 2010;7():276.
2010: Walter Jaoko; Etienne Karita; Kayitesi Kayitenkore; Gloria Omosa-Manyonyi; Susan Allen; Soe Than; Elizabeth M Adams; Barney S Graham; Richard A Koup; Robert T Bailer; Carol Smith; Len Dally; Bashir Farah; Omu Anzala; Claude M Muvunyi; Jean Bizimana; Tony Tarragona-Fiol; Philip J Bergin; Peter Hayes; Martin Ho; Kelley Loughran; Wendy Komaroff; Gwynneth Stevens; Helen Thomson; Mark J Boaz; Josephine H Cox; Claudia Schmidt; Jill Gilmour; Gary Nabel; Patricia Fast; Job Bwayo
Safety and immunogenicity study of Multiclade HIV-1 adenoviral vector vaccine alone or as boost following a multiclade HIV-1 DNA vaccine in Africa.
PloS one 2010;5(9):e12873.
2010: Eric S Rosenberg; Barney S Graham; Ellen S Chan; Ronald J Bosch; Vicki Stocker; Janine Maenza; Martin Markowitz; Susan Little; Paul E Sax; Ann C Collier; Gary Nabel; Suzanne Saindon; Theresa Flynn; Daniel Kuritzkes; Dan H Barouch
Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection.
PloS one 2010;5(5):e10555.
2010: SRINIVAS RAO; Wing-Pui Kong; Chih-Jen Wei; Neal Van Hoeven; J Patrick Gorres; Martha Nason; Hanne Andersen; Terrence M Tumpey; Gary Nabel
Comparative efficacy of hemagglutinin, nucleoprotein, and matrix 2 protein gene-based vaccination against H5N1 influenza in mouse and ferret.
PloS one 2010;5(3):e9812.
2010: Richard A Koup; Mario Roederer; Laurie Lamoreaux; Jennifer Fischer; Laura Novik; Martha C Nason; Brenda D Larkin; Mary E Enama; Julie E Ledgerwood; Robert T Bailer; John R Mascola; Gary Nabel; Barney S Graham
Priming immunization with DNA augments immunogenicity of recombinant adenoviral vectors for both HIV-1 specific antibody and T-cell responses.
PloS one 2010;5(2):e9015.
2010: Aravind Basavapathruni; Wendy W Yeh; Rory T Coffey; James B Whitney; Peter T Hraber; Ayush Giri; Bette T Korber; SRINIVAS RAO; Gary Nabel; John R Mascola; Michael S Seaman; Norman L Letvin
Envelope vaccination shapes viral envelope evolution following simian immunodeficiency virus infection in rhesus monkeys.
Journal of virology 2010;84(2):953-63.
2010: Cheng Cheng; Jason G D Gall; Martha Nason; C Richter King; Richard A Koup; Mario Roederer; M Juliana McElrath; Cecilia A Morgan; Gavin Churchyard; Lindsey R Baden; Ann C Duerr; Michael C Keefer; Barney S Graham; Gary Nabel
Differential specificity and immunogenicity of adenovirus type 5 neutralizing antibodies elicited by natural infection or immunization.
Journal of virology 2010;84(1):630-8.
2009: Lei Chen; Young Do Kwon; Tongqing Zhou; Xueling Wu; Sijy O'Dell; Lisa Cavacini; Ann J Hessell; Marie Pancera; Min Tang; Ling Xu; Zhi-Yong Yang; Mei-Yun Zhang; James Arthos; Dennis R Burton; Dimiter S Dimitrov; Gary Nabel; Marshall R Posner; Joseph Sodroski; Richard Wyatt; John R Mascola; Peter D Kwong
Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science (New York, N.Y.) 2009;326(5956):1123-7.
2009: Peter D Kwong; John R Mascola; Gary Nabel
Mining the B cell repertoire for broadly neutralizing monoclonal antibodies to HIV-1.
Cell host & microbe 2009;6(4):292-4.
2009: Gary Nabel
Philosophy of science. The coordinates of truth.
Science (New York, N.Y.) 2009;326(5949):53-4.
2009: Rino Rappuoli; Giuseppe Del Giudice; Gary Nabel; Albert D M E Osterhaus; Robin Robinson; David Salisbury; Klaus Stöhr; John J Treanor
Public health. Rethinking influenza.
Science (New York, N.Y.) 2009;326(5949):50.
2009: Yue Sun; Robert T Bailer; SRINIVAS RAO; John R Mascola; Gary Nabel; Richard A Koup; Norman L Letvin
Systemic and mucosal T-lymphocyte activation induced by recombinant adenovirus vaccines in rhesus monkeys.
Journal of virology 2009;83(20):10596-604.
2009: James B Whitney; Corinne Luedemann; Peter Hraber; SRINIVAS RAO; John R Mascola; Gary Nabel; Norman L Letvin
T-cell vaccination reduces simian immunodeficiency virus levels in semen.
Journal of virology 2009;83(20):10840-3.
2009: Sampa Santra; Yue Sun; Birgit Korioth-Schmitz; Julie Fitzgerald; Cherie Charbonneau; Giannina Santos; Michael S Seaman; Sarah J Ratcliffe; David C Montefiori; Gary Nabel; Hildegund C J Ertl; Norman L Letvin
Heterologous prime/boost immunizations of rhesus monkeys using chimpanzee adenovirus vectors.
Vaccine 2009;27(42):5837-45.
2009: B S Graham; J E Ledgerwood; Gary Nabel
Vaccine development in the twenty-first century: changing paradigms for elusive viruses.
Clinical pharmacology and therapeutics 2009;86(3):234-6.
2009: Mitsuo Honda; Rui Wang; Wing-Pui Kong; Masaru Kanekiyo; Wataru Akahata; Ling Xu; Kazuhiro Matsuo; Kannan Natarajan; Howard Robinson; Tedi E Asher; David A Price; Daniel C Douek; David Margulies; Gary Nabel
Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2425-34.
2009: Gary Nabel
Protecting against future shock--inhalational anthrax.
The New England journal of medicine 2009;361(2):191-3.
2009: Lingshu Wang; Cheng Cheng; Sung-Youl Ko; Wing-Pui Kong; Masaru Kanekiyo; David Einfeld; Richard M Schwartz; C Richter King; Jason G D Gall; Gary Nabel
Delivery of human immunodeficiency virus vaccine vectors to the intestine induces enhanced mucosal cellular immunity.
Journal of virology 2009;83(14):7166-75.
2009: Brandon F Keele; Hui Li; Gerald Learn; Peter Hraber; Elena E Giorgi; Truman Grayson; Chuanxi Sun; Yalu Chen; Wendy W Yeh; Norman L Letvin; John R Mascola; Gary Nabel; Barton F Haynes; Tanmoy Bhattacharya; Alan S Perelson; Bette T Korber; Beatrice H Hahn; George M Shaw
Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1.
The Journal of experimental medicine 2009;206(5):1117-34.
2009: Barna Dey; Krisha Svehla; Ling Xu; Dianne Wycuff; Tongqing Zhou; Gerald Voss; Adhuna Phogat; Bimal K Chakrabarti; Yuxing Li; George Shaw; Peter D Kwong; Gary Nabel; John R Mascola; Richard Wyatt
Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site.
PLoS pathogens 2009;5(5):e1000445.
2009: Nancy J Sullivan; Julie E Martin; Barney S Graham; Gary Nabel
Correlates of protective immunity for Ebola vaccines: implications for regulatory approval by the animal rule.
Nature reviews. Microbiology 2009;7(5):393-400.
2009: Lan Wu; Tongqing Zhou; Zhi-Yong Yang; Krisha Svehla; Sijy O'Dell; Mark K Louder; Ling Xu; John R Mascola; Dennis R Burton; James A Hoxie; Robert W Doms; Peter D Kwong; Gary Nabel
Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain.
Journal of virology 2009;83(10):5077-86.
2009: SRINIVAS RAO; D Styles; W Kong; C Andrews; J P Gorres; Gary Nabel
A gene-based avian influenza vaccine in poultry.
Poultry science 2009;88(4):860-6.
2009: Wing-Pui Kong; Lan Wu; Timothy C Wallstrom; Will Fischer; Zhi-Yong Yang; Sung-Youl Ko; Norman L Letvin; Barton F Haynes; Beatrice H Hahn; Bette Korber; Gary Nabel
Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination.
Journal of virology 2009;83(5):2201-15.
2009: Cameron P Keating; Melissa K Hill; David J Hawkes; Redmond P Smyth; Catherine Isel; Shu-Yun Le; Ann C Palmenberg; John A Marshall; Roland Marquet; Gary Nabel; Johnson Mak
The A-rich RNA sequences of HIV-1 pol are important for the synthesis of viral cDNA.
Nucleic acids research 2009;37(3):945-56.
2009: Sung-Youl Ko; Cheng Cheng; Wing-Pui Kong; Lingshu Wang; Masaru Kanekiyo; David Einfeld; C Richter King; Jason G D Gall; Gary Nabel
Enhanced induction of intestinal cellular immunity by oral priming with enteric adenovirus 41 vectors.
Journal of virology 2009;83(2):748-56.
2008: Julie E Martin; Mark K Louder; LaSonji A Holman; Ingelise J Gordon; Mary E Enama; Brenda D Larkin; Charla A Andrews; Leatrice Vogel; Richard A Koup; Mario Roederer; Robert T Bailer; Phillip L Gomez; Martha Nason; John R Mascola; Gary Nabel; Barney S Graham
A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial.
Vaccine 2008;26(50):6338-43.
2008: Igor M Belyakov; Jeffrey D Ahlers; Gary Nabel; Bernard Moss; Jay A Berzofsky
Generation of functionally active HIV-1 specific CD8+ CTL in intestinal mucosa following mucosal, systemic or mixed prime-boost immunization.
Virology 2008;381(1):106-15.
2008: Xueling Wu; Anna Sambor; Martha C Nason; Zhi-Yong Yang; Lan Wu; Susan Zolla-Pazner; Gary Nabel; John R Mascola
Soluble CD4 broadens neutralization of V3-directed monoclonal antibodies and guinea pig vaccine sera against HIV-1 subtype B and C reference viruses.
Virology 2008;380(2):285-95.
2008: Sampa Santra; Bette T Korber; Mark Muldoon; Dan H Barouch; Gary Nabel; Feng Gao; Beatrice H Hahn; Barton F Haynes; Norman L Letvin
A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(30):10489-94.
2008: Wei Shi; Yue Huang; Mark Sutton-Smith; Berangere Tissot; Maria Panico; Howard R Morris; Anne Dell; Stuart M Haslam; Jeffrey Boyington; Barney S Graham; Zhi-Yong Yang; Gary Nabel
A filovirus-unique region of Ebola virus nucleoprotein confers aberrant migration and mediates its incorporation into virions.
Journal of virology 2008;82(13):6190-9.
2008: Chih-Jen Wei; Ling Xu; Wing-Pui Kong; Wei Shi; Kevin Canis; James Stevens; Zhi-Yong Yang; Anne Dell; Stuart M Haslam; Ian A Wilson; Gary Nabel
Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus.
Journal of virology 2008;82(13):6200-8.
2008: Kwanyee Leung; Jae-Ouk Kim; Lakshmanan Ganesh; Juraj Kabat; Owen Schwartz; Gary Nabel
HIV-1 assembly: viral glycoproteins segregate quantally to lipid rafts that associate individually with HIV-1 capsids and virions.
Cell host & microbe 2008;3(5):285-92.
2008: SRINIVAS RAO; Wing-Pui Kong; Chih-Jen Wei; Zhi-Yong Yang; Martha Nason; Darrel Styles; Louis J DeTolla; Aruna Panda; Erin M Sorrell; Haichen Song; Hongquan Wan; Gloria C Ramirez-Nieto; Daniel Perez; Gary Nabel
Multivalent HA DNA vaccination protects against highly pathogenic H5N1 avian influenza infection in chickens and mice.
PloS one 2008;3(6):e2432.
2007: Julie E Martin; Theodore C Pierson; Sarah Hubka; Steve Rucker; Ingelise J Gordon; Mary E Enama; Charla A Andrews; Qing Xu; Brent S Davis; Martha Nason; Michael Fay; Richard A Koup; Mario Roederer; Robert T Bailer; Phillip L Gomez; John R Mascola; Gwong-Jen J Chang; Gary Nabel; Barney S Graham
A West Nile virus DNA vaccine induces neutralizing antibody in healthy adults during a phase 1 clinical trial.
The Journal of infectious diseases 2007;196(12):1732-40.
2007: Carisa A Zampieri; Nancy J Sullivan; Gary Nabel
Immunopathology of highly virulent pathogens: insights from Ebola virus.
Nature immunology 2007;8(11):1159-64.
2007: Norman L Letvin; SRINIVAS RAO; Vi Dang; Adam P Buzby; Birgit Korioth-Schmitz; Dilani Dombagoda; Jenny G Parvani; Ryon H Clarke; Liat Bar; Kevin R Carlson; Pamela A Kozlowski; Vanessa M Hirsch; John R Mascola; Gary Nabel
No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys.
Journal of virology 2007;81(22):12368-74.
2007: Zhi-Yong Yang; Chih-Jen Wei; Wing-Pui Kong; Lan Wu; Ling Xu; David Smith; Gary Nabel
Immunization by avian H5 influenza hemagglutinin mutants with altered receptor binding specificity.
Science (New York, N.Y.) 2007;317(5839):825-8.
2007: Zhongyu Zhu; Samitabh Chakraborti; Yuxian He; Anjeanette Roberts; Timothy Sheahan; Xiaodong Xiao; Lisa E Hensley; Prabakaran Ponraj; Barry Rockx; Igor Sidorov; Davide Corti; Leatrice Vogel; Yang Feng; Jae-Ouk Kim; Lin-Fa Wang; Ralph S Baric; Antonio Lanzavecchia; Kris Curtis; Gary Nabel; Kanta Subbarao; Shibo Jiang; Dimiter S Dimitrov
Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):12123-8.
2007: Gary Nabel
Mapping the future of HIV vaccines.
Nature reviews. Microbiology 2007;5(7):482-4.
2007: Andrew T Catanzaro; Mario Roederer; Richard A Koup; Robert T Bailer; Mary E Enama; Martha C Nason; Julie E Martin; Steve Rucker; Charla A Andrews; Phillip L Gomez; John R Mascola; Gary Nabel; Barney S Graham
Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine.
Vaccine 2007;25(20):4085-92.
2007: Jorge A Tavel; Julie E Martin; Grace G Kelly; Mary E Enama; Jean M Shen; Phillip L Gomez; Charla A Andrews; Richard A Koup; Robert T Bailer; Judy A Stein; Mario Roederer; Gary Nabel; Barney S Graham
Safety and immunogenicity of a Gag-Pol candidate HIV-1 DNA vaccine administered by a needle-free device in HIV-1-seronegative subjects.
Journal of acquired immune deficiency syndromes (1999) 2007;44(5):601-5.
2007: Franck Lemiale; Hedi Haddada; Gary Nabel; Douglas E Brough; C Richter King; Jason G D Gall
Novel adenovirus vaccine vectors based on the enteric-tropic serotype 41.
Vaccine 2007;25(11):2074-84.
2007: Alvin L Smith; Lakshmanan Ganesh; Kwanyee Leung; Jenny Jongstra-Bilen; Jan Jongstra; Gary Nabel
Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells.
The Journal of experimental medicine 2007;204(2):421-30.
2007: Tongqing Zhou; Ling Xu; Barna Dey; Ann J Hessell; Donald Van Ryk; Shi-Hua Xiang; Xinzhen Yang; Mei-Yun Zhang; Michael B Zwick; James Arthos; Dennis R Burton; Dimiter S Dimitrov; Joseph Sodroski; Richard Wyatt; Gary Nabel; Peter D Kwong
Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature 2007;445(7129):732-7.
2007: Yuuei Shu; Sarah Winfrey; Zhi-Yong Yang; Ling Xu; SRINIVAS RAO; Indresh K Srivastava; Susan W Barnett; Gary Nabel; John R Mascola
Efficient protein boosting after plasmid DNA or recombinant adenovirus immunization with HIV-1 vaccine constructs.
Vaccine 2007;25(8):1398-408.
2007: Cheng Cheng; Jason G D Gall; Wing-Pui Kong; Rebecca L Sheets; Phillip L Gomez; C Richter King; Gary Nabel
Mechanism of ad5 vaccine immunity and toxicity: fiber shaft targeting of dendritic cells.
PLoS pathogens 2007;3(2):e25.
2007: Carisa A Zampieri; Jean-Francois Fortin; Garry P Nolan; Gary Nabel
The ERK mitogen-activated protein kinase pathway contributes to Ebola virus glycoprotein-induced cytotoxicity.
Journal of virology 2007;81(3):1230-40.
2007: Jae-Ouk Kim; Bimal K Chakrabarti; Anuradha Guha-Niyogi; Mark K Louder; John R Mascola; Lakshmanan Ganesh; Gary Nabel
Lysis of human immunodeficiency virus type 1 by a specific secreted human phospholipase A2.
Journal of virology 2007;81(3):1444-50.
2006: Barney S Graham; Richard A Koup; Mario Roederer; Robert T Bailer; Mary E Enama; Zoe Moodie; Julie E Martin; Margaret M McCluskey; Bimal K Chakrabarti; Laurie Lamoreaux; Charla A Andrews; Phillip L Gomez; John R Mascola; Gary Nabel
Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 DNA candidate vaccine.
The Journal of infectious diseases 2006;194(12):1650-60.
2006: Andrew T Catanzaro; Richard A Koup; Mario Roederer; Robert T Bailer; Mary E Enama; Zoe Moodie; Lin Gu; Julie E Martin; Laura Novik; Bimal K Chakrabarti; Bryan Butman; Jason G D Gall; C Richter King; Charla A Andrews; Rebecca L Sheets; Phillip L Gomez; John R Mascola; Gary Nabel; Barney S Graham
Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector.
The Journal of infectious diseases 2006;194(12):1638-49.
2006: Julie E Martin; Nancy J Sullivan; Mary E Enama; Ingelise J Gordon; Mario Roederer; Richard A Koup; Robert T Bailer; Bimal K Chakrabarti; Michael A Bailey; Phillip L Gomez; Charla A Andrews; Zoe Moodie; Lin Gu; Judith A Stein; Gary Nabel; Barney S Graham
A DNA vaccine for Ebola virus is safe and immunogenic in a phase I clinical trial.
Clinical and vaccine immunology : CVI 2006;13(11):1267-77.
2006: Yue Sun; Joern schmitz; Adam P Buzby; Brianne R Barker; SRINIVAS RAO; Ling Xu; Zhi-Yong Yang; John R Mascola; Gary Nabel; Norman L Letvin
Virus-specific cellular immune correlates of survival in vaccinated monkeys after simian immunodeficiency virus challenge.
Journal of virology 2006;80(22):10950-6.
2006: Jae-Sung Yu; Hua-Xin Liao; Aren E Gerdon; Brian Huffman; Richard M Scearce; Mildred McAdams; S Munir Alam; Paul M Popernack; Nancy J Sullivan; David Wright; David E Cliffel; Gary Nabel; Barton F Haynes
Detection of Ebola virus envelope using monoclonal and polyclonal antibodies in ELISA, surface plasmon resonance and a quartz crystal microbalance immunosensor.
Journal of virological methods 2006;137(2):219-28.
2006: Wing-Pui Kong; Chantelle Ahlenstiel; Zhi-Yong Yang; Chih-Jen Wei; Ling Xu; Adolfo García-Sastre; Terrence M Tumpey; Gary Nabel
Protective immunity to lethal challenge of the 1918 pandemic influenza virus by vaccination.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(43):15987-91.
2006: Hua-Xin Liao; Laura L Sutherland; Shi-Mao Xia; Mary E Brock; Richard M Scearce; Stacie Vanleeuwen; S Munir Alam; Mildred McAdams; Eric A Weaver; Zenaido T Camacho; Ben-Jiang Ma; Yingying Li; Julie M Decker; Gary Nabel; David C Montefiori; Beatrice H Hahn; Bette T Korber; Feng Gao; Barton F Haynes
A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses.
Virology 2006;353(2):268-82.
2006: Eric A Weaver; Zhongjing Lu; Zenaido T Camacho; Fatiha Moukdar; Hua-Xin Liao; Ben-Jiang Ma; Mark Muldoon; James Theiler; Gary Nabel; Norman L Letvin; Bette T Korber; Beatrice H Hahn; Barton F Haynes; Feng Gao
Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen.
Journal of virology 2006;80(14):6745-56.
2006: Joseph J Mattapallil; Daniel C Douek; Alicia Buckler-White; David Montefiori; Norman L Letvin; Gary Nabel; Mario Roederer
Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge.
The Journal of experimental medicine 2006;203(6):1533-41.
2006: Norman L Letvin; John R Mascola; Yue Sun; Darci A Gorgone; Adam P Buzby; Ling Xu; Zhi-Yong Yang; Bimal K Chakrabarti; SRINIVAS RAO; Joern schmitz; David C Montefiori; Brianne R Barker; Fred L Bookstein; Gary Nabel
Preserved CD4+ central memory T cells and survival in vaccinated SIV-challenged monkeys.
Science (New York, N.Y.) 2006;312(5779):1530-3.
2006: Lan Wu; Zhi-Yong Yang; Ling Xu; Brent Welcher; Sarah Winfrey; Yiming Shao; John R Mascola; Gary Nabel
Cross-clade recognition and neutralization by the V3 region from clade C human immunodeficiency virus-1 envelope.
Vaccine 2006;24(23):4995-5002.
2006: Nancy J Sullivan; Thomas W Geisbert; Joan B Geisbert; Devon Shedlock; Ling Xu; Laurie Lamoreaux; Jerome H H V Custers; Paul M Popernack; Zhi-Yong Yang; Maria G Pau; Mario Roederer; Richard A Koup; Jaap Goudsmit; Peter B Jahrling; Gary Nabel
Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs.
PLoS medicine 2006;3(6):e177.
2006: Rebecca L Sheets; Judith Stein; Timothy Scott Manetz; Chris Duffy; Martha Nason; Charla Andrews; Wing-Pui Kong; Gary Nabel; Phillip L Gomez
Biodistribution of DNA plasmid vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile virus is similar, without integration, despite differing plasmid backbones or gene inserts.
Toxicological sciences : an official journal of the Society of Toxicology 2006;91(2):610-9.
2006: Lakshmanan Ganesh; Takanobu Yoshimoto; Narayani C Moorthy; Wataru Akahata; Manfred Boehm; Elizabeth G Nabel; Gary Nabel
Protein methyltransferase 2 inhibits NF-kappaB function and promotes apoptosis.
Molecular and cellular biology 2006;26(10):3864-74.
2006: Paula M Acierno; Joern schmitz; Darci A Gorgone; Yue Sun; Sampa Santra; Michael S Seaman; Michael H Newberg; John R Mascola; Gary Nabel; Dennis Panicali; Norman L Letvin
Preservation of functional virus-specific memory CD8+ T lymphocytes in vaccinated, simian human immunodeficiency virus-infected rhesus monkeys.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(9):5338-45.
2006: Daniel C Douek; Peter D Kwong; Gary Nabel
The rational design of an AIDS vaccine.
Cell 2006;124(4):677-81.
2006: SRINIVAS RAO; Phillip Gomez; John R Mascola; Vi Dang; Georgia R Krivulka; Faye Yu; Carol I Lord; Ling Shen; Robert T Bailer; Gary Nabel; Norman L Letvin
Comparative evaluation of three different intramuscular delivery methods for DNA immunization in a nonhuman primate animal model.
Vaccine 2006;24(3):367-73.
2005: Suzanne L Epstein; Wing-Pui Kong; Julia A Misplon; Chia-Yun Lo; Terrence M Tumpey; Ling Xu; Gary Nabel
Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein.
Vaccine 2005;23(46-47):5404-10.
2005: Wing-Pui Kong; Ling Xu; Konrad Stadler; Jeffrey B Ulmer; Sergio Abrignani; Rino Rappuoli; Gary Nabel
Modulation of the immune response to the severe acute respiratory syndrome spike glycoprotein by gene-based and inactivated virus immunization.
Journal of virology 2005;79(22):13915-23.
2005: Keith A Reimann; Robert A Parker; Michael S Seaman; Kristin Beaudry; Margaret H Beddall; Lauren Peterson; Kenneth C Williams; Ronald S Veazey; David C Montefiori; John R Mascola; Gary Nabel; Norman L Letvin
Pathogenicity of simian-human immunodeficiency virus SHIV-89.6P and SIVmac is attenuated in cynomolgus macaques and associated with early T-lymphocyte responses.
Journal of virology 2005;79(14):8878-85.
2005: Dan H Barouch; Zhi-Yong Yang; Wing-Pui Kong; Birgit Korioth-Schmitz; Shawn M Sumida; Diana M Truitt; Michael G Kishko; Janelle C Arthur; Ayako Miura; John R Mascola; Norman L Letvin; Gary Nabel
A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates.
Journal of virology 2005;79(14):8828-34.
2005: Greg M Podsakoff; Barbara C Engel; Denise A Carbonaro; Chris Choi; Elzbieta Monika Smogorzewska; Gerhard Bauer; David Selander; Susan Csik; Kathy Wilson; Michael R Betts; Richard A Koup; Gary Nabel; D Keith Bishop; Steven R King; Manfred Schmidt; Christof von Kalle; Joseph A Church; Donald B Kohn
Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34(+) cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(1):77-86.
2005: Lan Wu; Wing-Pui Kong; Gary Nabel
Enhanced breadth of CD4 T-cell immunity by DNA prime and adenovirus boost immunization to human immunodeficiency virus Env and Gag immunogens.
Journal of virology 2005;79(13):8024-31.
2005: Gary Nabel
Immunology. Close to the edge: neutralizing the HIV-1 envelope.
Science (New York, N.Y.) 2005;308(5730):1878-9.
2005: Bimal K Chakrabarti; Xu Ling; Zhi-Yong Yang; David C Montefiori; Amos Panet; Wing-Pui Kong; Brent Welcher; Mark K Louder; John R Mascola; Gary Nabel
Expanded breadth of virus neutralization after immunization with a multiclade envelope HIV vaccine candidate.
Vaccine 2005;23(26):3434-45.
2005: Sampa Santra; Michael S Seaman; Ling Xu; Dan H Barouch; Carol I Lord; Michelle A Lifton; Darci A Gorgone; Kristin Beaudry; Krisha Svehla; Brent Welcher; Bimal K Chakrabarti; Yue Huang; Zhi-Yong Yang; John R Mascola; Gary Nabel; Norman L Letvin
Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates.
Journal of virology 2005;79(10):6516-22.
2005: Yue Sun; Joern schmitz; Paula M Acierno; Sampa Santra; Ramu A Subbramanian; Dan H Barouch; Darci A Gorgone; Michelle A Lifton; Kristin Beaudry; Kelledy Manson; Valerie Philippon; Ling Xu; Holden T Maecker; John R Mascola; Dennis Panicali; Gary Nabel; Norman L Letvin
Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):4753-60.
2005: Michael S Seaman; Sampa Santra; Michael H Newberg; Valerie Philippon; Kelledy Manson; Ling Xu; Rebecca Gelman; Dennis Panicali; John R Mascola; Gary Nabel; Norman L Letvin
Vaccine-elicited memory cytotoxic T lymphocytes contribute to Mamu-A*01-associated control of simian/human immunodeficiency virus 89.6P replication in rhesus monkeys.
Journal of virology 2005;79(8):4580-8.
2005: Michael S Seaman; Ling Xu; Kristin Beaudry; Kristi L Martin; Margaret H Beddall; Ayako Miura; Anna Sambor; Bimal K Chakrabarti; Yue Huang; Robert T Bailer; Richard A Koup; John R Mascola; Gary Nabel; Norman L Letvin
Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys.
Journal of virology 2005;79(5):2956-63.
2005: Dan H Barouch; Gary Nabel
Adenovirus vector-based vaccines for human immunodeficiency virus type 1.
Human gene therapy 2005;16(2):149-56.
2005: Zhi-Yong Yang; Heidi C Werner; Wing-Pui Kong; Kwanyee Leung; Elisabetta Traggiai; Antonio Lanzavecchia; Gary Nabel
Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):797-801.
2005: John R Mascola; Anna Sambor; Kristin Beaudry; Sampa Santra; Brent Welcher; Mark K Louder; Thomas C VanCott; Yue Huang; Bimal K Chakrabarti; Wing-Pui Kong; Zhi-Yong Yang; Ling Xu; David C Montefiori; Gary Nabel; Norman L Letvin
Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins.
Journal of virology 2005;79(2):771-9.
2005: Wataru Akahata; Zhi-Yong Yang; Gary Nabel
Comparative immunogenicity of human immunodeficiency virus particles and corresponding polypeptides in a DNA vaccine.
Journal of virology 2005;79(1):626-31.
2005: Nancy J Sullivan; Mary Peterson; Zhi-Yong Yang; Wing-Pui Kong; Heinricus Duckers; Elizabeth G Nabel; Gary Nabel
Ebola virus glycoprotein toxicity is mediated by a dynamin-dependent protein-trafficking pathway.
Journal of virology 2005;79(1):547-53.
2004: Yue Huang; Zhi-Yong Yang; Wing-Pui Kong; Gary Nabel
Generation of synthetic severe acute respiratory syndrome coronavirus pseudoparticles: implications for assembly and vaccine production.
Journal of virology 2004;78(22):12557-65.
2004: Lakshmanan Ganesh; Kwanyee Leung; Karin Loré; Reuven Levin; Amos Panet; Owen Schwartz; Richard A Koup; Gary Nabel
Infection of specific dendritic cells by CCR5-tropic human immunodeficiency virus type 1 promotes cell-mediated transmission of virus resistant to broadly neutralizing antibodies.
Journal of virology 2004;78(21):11980-7.
2004: Norman L Letvin; Yue Huang; Bimal K Chakrabarti; Ling Xu; Michael S Seaman; Kristin Beaudry; Birgit Korioth-Schmitz; Faye Yu; Daniela Rohne; Kristi L Martin; Ayako Miura; Wing-Pui Kong; Zhi-Yong Yang; Rebecca Gelman; Olga G Golubeva; David C Montefiori; John R Mascola; Gary Nabel
Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys.
Journal of virology 2004;78(14):7490-7.
2004: Zhi-Yong Yang; Yue Huang; Lakshmanan Ganesh; Kwanyee Leung; Wing-Pui Kong; Owen Schwartz; Kanta Subbarao; Gary Nabel
pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN.
Journal of virology 2004;78(11):5642-50.
2004: Dan H Barouch; Maria G Pau; Jerome H H V Custers; Wouter Koudstaal; Stefan Kostense; Menzo J E Havenga; Diana M Truitt; Shawn M Sumida; Michael G Kishko; Janelle C Arthur; Birgit Korioth-Schmitz; Michael H Newberg; Darci A Gorgone; Michelle A Lifton; Dennis Panicali; Gary Nabel; Norman L Letvin; Jaap Goudsmit
Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):6290-7.
2004: Zhi-Yong Yang; Bimal K Chakrabarti; Ling Xu; Brent Welcher; Wing-Pui Kong; Kwanyee Leung; Amos Panet; John R Mascola; Gary Nabel
Selective modification of variable loops alters tropism and enhances immunogenicity of human immunodeficiency virus type 1 envelope.
Journal of virology 2004;78(8):4029-36.
2004: Zhi-Yong Yang; Wing-Pui Kong; Yue Huang; Anjeanette Roberts; Brian Murphy; Kanta Subbarao; Gary Nabel
A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice.
Nature 2004;428(6982):561-4.
2004: Dennis R Burton; Ronald C Desrosiers; Robert W Doms; Wayne C Koff; Peter D Kwong; John P Moore; Gary Nabel; Joseph Sodroski; Ian A Wilson; Richard Wyatt
HIV vaccine design and the neutralizing antibody problem.
Nature immunology 2004;5(3):233-6.
2004: Gary Nabel
Genetic, cellular and immune approaches to disease therapy: past and future.
Nature medicine 2004;10(2):135-41.
2004: Ezra Burstein; Lakshmanan Ganesh; Robert D Dick; Bart van De Sluis; John C Wilkinson; Leo W J Klomp; Cisca Wijmenga; George J Brewer; Gary Nabel; Colin S Duckett
A novel role for XIAP in copper homeostasis through regulation of MURR1.
The EMBO journal 2004;23(1):244-54.
2004: Shan Cen; Meijuan Niu; Jenan Saadatmand; Fei Guo; Yue Huang; Gary Nabel; Lawrence Kleiman
Incorporation of pol into human immunodeficiency virus type 1 Gag virus-like particles occurs independently of the upstream Gag domain in Gag-pol.
Journal of virology 2004;78(2):1042-9.
2003: Lakshmanan Ganesh; Ezra Burstein; Anuradha Guha-Niyogi; Mark K Louder; John R Mascola; Leo W J Klomp; Cisca Wijmenga; Colin S Duckett; Gary Nabel
The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes.
Nature 2003;426(6968):853-7.
2003: Wing-Pui Kong; Yue Huang; Zhi-Yong Yang; Bimal K Chakrabarti; Zoe Moodie; Gary Nabel
Immunogenicity of multiple gene and clade human immunodeficiency virus type 1 DNA vaccines.
Journal of virology 2003;77(23):12764-72.
2003: Franck Lemiale; Wing-Pui Kong; Levent M Akyürek; Xu Ling; Yue Huang; Bimal K Chakrabarti; Michael Eckhaus; Gary Nabel
Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system.
Journal of virology 2003;77(18):10078-87.
2003: Nancy J Sullivan; Zhi-Yong Yang; Gary Nabel
Ebola virus pathogenesis: implications for vaccines and therapies.
Journal of virology 2003;77(18):9733-7.
2003: Marc Tritel; Amy M Stoddard; Barbara J Flynn; Patricia A Darrah; Chang-you Wu; Ulrike Wille; Javeed A Shah; Yue Huang; Ling Xu; Michael R Betts; Gary Nabel; Robert A Seder
Prime-boost vaccination with HIV-1 Gag protein and cytosine phosphate guanosine oligodeoxynucleotide, followed by adenovirus, induces sustained and robust humoral and cellular immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2538-47.
2003: Nancy J Sullivan; Thomas W Geisbert; Joan B Geisbert; Ling Xu; Zhi-Yong Yang; Mario Roederer; Richard A Koup; Peter B Jahrling; Gary Nabel
Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates.
Nature 2003;424(6949):681-4.
2003: Dan H Barouch; Paul F McKay; Shawn M Sumida; Sampa Santra; Shawn S Jackson; Darci A Gorgone; Michelle A Lifton; Bimal K Chakrabarti; Ling Xu; Gary Nabel; Norman L Letvin
Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines.
Journal of virology 2003;77(16):8729-35.
2003: Richard D Klausner; Anthony Fauci; Lawrence Corey; Gary Nabel; Helene Gayle; Seth Berkley; Barton F Haynes; David Baltimore; Chris Collins; R Gordon Douglas; Jose Esparza; Donald P Francis; N K Ganguly; Julie L Gerberding; Margaret I Johnston; Michel D Kazatchkine; Andrew J McMichael; Malegapuru W Makgoba; Giuseppe Pantaleo; Peter Piot; Yiming Shao; Edmund C Tramont; Harold Varmus; Judith N Wasserheit
Medicine. The need for a global HIV vaccine enterprise.
Science (New York, N.Y.) 2003;300(5628):2036-9.
2003: Gary Nabel
Vaccine for AIDS and Ebola virus infection.
Virus research 2003;92(2):213-7.
2003: Gary Nabel
Cancer gene therapy: present status and future directions.
Ernst Schering Research Foundation workshop 2003;(43):81-8.
2003: Gary Nabel
The future of gene therapy.
Ernst Schering Research Foundation workshop 2003;(43):1-16.
2003: Zhi-Yong Yang; Linda S Wyatt; Wing-Pui Kong; Zoe Moodie; Bernard Moss; Gary Nabel
Overcoming immunity to a viral vaccine by DNA priming before vector boosting.
Journal of virology 2003;77(1):799-803.
2002: Jamal Baig; Daniel B Levy; Paul F McKay; Joern schmitz; Sampa Santra; Ramu A Subbramanian; Marcelo J Kuroda; Michelle A Lifton; Darci A Gorgone; Linda S Wyatt; Bernard Moss; Yue Huang; Bimal K Chakrabarti; Ling Xu; Wing-Pui Kong; Zhi-Yong Yang; John R Mascola; Gary Nabel; Angela Carville; Andrew Lackner; Ronald S Veazey; Norman L Letvin
Elicitation of simian immunodeficiency virus-specific cytotoxic T lymphocytes in mucosal compartments of rhesus monkeys by systemic vaccination.
Journal of virology 2002;76(22):11484-90.
2002: Yue Huang; Ling Xu; Yongnian Sun; Gary Nabel
The assembly of Ebola virus nucleocapsid requires virion-associated proteins 35 and 24 and posttranslational modification of nucleoprotein.
Molecular cell 2002;10(2):307-16.
2002: Manfred Boehm; Takanobu Yoshimoto; Martin F Crook; Shriram Nallamshetty; Andrea L True; Gary Nabel; Elizabeth G Nabel
A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.
The EMBO journal 2002;21(13):3390-401.
2002: Gary Nabel; William Makgoba; Jose Esparza
HIV-1 diversity and vaccine development.
Science (New York, N.Y.) 2002;296(5577):2335.
2002: Bimal K Chakrabarti; Wing-Pui Kong; Bei-yue Wu; Zhi-Yong Yang; Jacques Friborg; Xu Ling; Steven R King; David C Montefiori; Gary Nabel
Modifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization.
Journal of virology 2002;76(11):5357-68.
2002: Luciana Borio; Thomas V Inglesby; Clarence Peters; Alan L Schmaljohn; James Hughes; Peter B Jahrling; Thomas Ksiazek; Karl M Johnson; Andrea Nikki Meyerhoff; Tara O'Toole; Michael S Ascher; John G Bartlett; Joel G Breman; Edward M Eitzen; Margaret Hamburg; Jerry Hauer; Donald A Henderson; Richard T Johnson; Gigi Kwik; Marcelle Layton; Scott R Lillibridge; Gary Nabel; Michael Osterholm; Trish M Perl; Philip Russell; Kevin Tonat
Hemorrhagic fever viruses as biological weapons: medical and public health management.
JAMA : the journal of the American Medical Association 2002;287(18):2391-405.
2002: Gary Nabel
HIV vaccine strategies.
Vaccine 2002;20(15):1945-7.
2002: Masayuki Kurooka; Gerard J Nuovo; Michael A Caligiuri; Gary Nabel
Cellular localization and function of Fas ligand (CD95L) in tumors.
Cancer research 2002;62(5):1261-5.
2002: Anne Moore; Wing-Pui Kong; Bimal K Chakrabarti; Gary Nabel
Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice.
Journal of virology 2002;76(1):243-50.
2001: John R Mascola; Gary Nabel
Vaccines for the prevention of HIV-1 disease.
Current opinion in immunology 2001;13(4):489-95.
2001: Kimberly E Foreman; Jacques Friborg; bala chandran; H Katano; T Sata; M Mercader; Gary Nabel; Brian J Nickoloff
Injection of human herpesvirus-8 in human skin engrafted on SCID mice induces Kaposi's sarcoma-like lesions.
Journal of dermatological science 2001;26(3):182-93.
2001: Heinricus Duckers; Manfred Boehm; Andrea L True; S F Yet; Hong San; J L Park; R Clinton Webb; M E Lee; Gary Nabel; Elizabeth G Nabel
Heme oxygenase-1 protects against vascular constriction and proliferation.
Nature medicine 2001;7(6):693-8.
2001: C Woffendin; Udaykumar Ranga; Gary Nabel
Development of molecular genetic interventions for HIV infection.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2001;Chapter 13():Unit 13.6.
2001: Levent M Akyürek; Shriram Nallamshetty; K Aoki; Hong San; Z Y Yang; Gary Nabel; Elizabeth G Nabel
Coexpression of guanylate kinase with thymidine kinase enhances prodrug cell killing in vitro and suppresses vascular smooth muscle cell proliferation in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(5 Pt 1):779-86.
2001: Yue Huang; Wing-Pui Kong; Gary Nabel
Human immunodeficiency virus type 1-specific immunity after genetic immunization is enhanced by modification of Gag and Pol expression.
Journal of virology 2001;75(10):4947-51.
2001: Gary Nabel
Challenges and opportunities for development of an AIDS vaccine.
Nature 2001;410(6831):1002-7.
2001: K Aoki; M Kurooka; J J Chen; J Petryniak; Elizabeth G Nabel; Gary Nabel
Extracellular matrix interacts with soluble CD95L: retention and enhancement of cytotoxicity.
Nature immunology 2001;2(4):333-7.
2001: R Rappuoli; Gary Nabel
Vaccines: ideal drugs for the 21st century?
Current opinion in investigational drugs (London, England : 2000) 2001;2(1):45-6.
2001: Gary Nabel
The Gordon Wilson Lecture: viruses and human disease.
Transactions of the American Clinical and Climatological Association 2001;112():79-84; discussion 86-8.
2000: Michael Hottiger; Gary Nabel
Viral replication and the coactivators p300 and CBP.
Trends in microbiology 2000;8(12):560-5.
2000: Nancy J Sullivan; A Sanchez; P E Rollin; Zhi-Yong Yang; Gary Nabel
Development of a preventive vaccine for Ebola virus infection in primates.
Nature 2000;408(6812):605-9.
2000: Y Sun; Frank T Kolligs; M O Hottiger; R Mosavin; Eric R Fearon; Gary Nabel
Regulation of beta -catenin transformation by the p300 transcriptional coactivator.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12613-8.
2000: Levent M Akyürek; ZY Yang; K Aoki; Hong San; Gary Nabel; M S Parmacek; Elizabeth G Nabel
SM22alpha promoter targets gene expression to vascular smooth muscle cells in vitro and in vivo.
Molecular medicine (Cambridge, Mass.) 2000;6(11):983-91.
2000: Gary Nabel; N J Sullivan
Antibodies and resistance to natural HIV infection.
The New England journal of medicine 2000;343(17):1263-5.
2000: Zhi-Yong Yang; Heinricus Duckers; Nancy J Sullivan; A Sanchez; Elizabeth G Nabel; Gary Nabel
Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury.
Nature medicine 2000;6(8):886-9.
2000: K Aoki; Levent M Akyürek; Hong San; K Leung; M S Parmacek; Elizabeth G Nabel; Gary Nabel
Restricted expression of an adenoviral vector encoding Fas ligand (CD95L) enhances safety for cancer gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(6):555-65.
2000: FC Tanner; Manfred Boehm; Levent M Akyürek; Hong San; ZY Yang; J Tashiro; Gary Nabel; Elizabeth G Nabel
Differential effects of the cyclin-dependent kinase inhibitors p27(Kip1), p21(Cip1), and p16(Ink4) on vascular smooth muscle cell proliferation.
Circulation 2000;101(17):2022-5.
2000: STEVEN ROSENBERG; R. Michael Blaese; M K Brenner; A B Deisseroth; F D Ledley; M T Lotze; J M Wilson; Gary Nabel; K Cornetta; J S Economou; S M Freeman; S R Riddell; M Brenner; E Oldfield; B Gansbacher; C Dunbar; Robert E Walker; F G Schuening; J A Roth; R G Crystal; M J Welsh; K Culver; H E Heslop; J Simons; R W Wilmott; R C Boucher; H F Siegler; J A Barranger; S Karlsson; D Kohn; J E Galpin; C Raffel; Charles Hesdorffer; J Ilan; Peter A Cassileth; J O'Shaughnessy; L E Kun; T K Das; F Wong-Staal; R E Sobol; R Haubrich; M Sznol; J Rubin; E J Sorcher; Joseph D Rosenblatt; R Walker; K Brigham; N Vogelzang; E Hersh; S L Eck
Human gene marker/therapy clinical protocols.
Human gene therapy 2000;11(6):919-79.
2000: E Aruga; Keishi Tanigawa; Atsushi Aruga; H Arai; J W Smith; B J Nickoloff; Gary Nabel; Alfred E Chang
CD95-mediated tumor recognition by CD4+ effector cells in a murine mammary model.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(2):225-34.
2000: S Ferrone; J F Finerty; Elizabeth M Jaffee; Gary Nabel
How much longer will tumour cells fool the immune system?
Immunology today 2000;21(2):70-2.
2000: Andrei L Kindzelskii; Z Yang; Gary Nabel; Robert F Todd III; Howard R Petty
Ebola virus secretory glycoprotein (sGP) diminishes Fc gamma RIIIB-to-CR3 proximity on neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):953-8.
1999: J Friborg; W Kong; M O Hottiger; Gary Nabel
p53 inhibition by the LANA protein of KSHV protects against cell death.
Nature 1999;402(6764):889-94.
1999: STEVEN ROSENBERG; R. Michael Blaese; M K Brenner; A B Deisseroth; F D Ledley; M T Lotze; J M Wilson; Gary Nabel; Kenneth Cornetta; J S Economou; S M Freeman; S R Riddell; E Oldfield; B Gansbacher; Cynthia Dunbar; Robert E Walker; F G Schuening; J A Roth; R G Crystal; M J Welsh; KW Culver; H E Heslop; J Simons; R W Wilmott; N A Habib
Human gene marker/therapy clinical protocols.
Human gene therapy 1999;10(18):3067-123.
1999: Michael Hottiger; T N Dam; Brian J Nickoloff; Timothy R B Johnson; Gary Nabel
Liposome-mediated gene transfer into human basal cell carcinoma.
Gene therapy 1999;6(12):1929-35.
1999: Kathleen L Collins; Gary Nabel
Naturally attenuated HIV--lessons for AIDS vaccines and treatment.
The New England journal of medicine 1999;340(22):1756-7.
1999: LK Felzien; S Farrell; J C Betts; R Mosavin; Gary Nabel
Specificity of cyclin E-Cdk2, TFIIB, and E1A interactions with a common domain of the p300 coactivator.
Molecular and cellular biology 1999;19(6):4241-6.
1999: T Koseki; Naohiro Inohara; Shiming Chen; R Carrio; J Merino; Michael Hottiger; Gary Nabel; Gabriel Núñez
CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10.
The Journal of biological chemistry 1999;274(15):9955-61.
1999: K Aoki; C Barker; Xavier Danthinne; Michael J Imperiale; Gary Nabel
Efficient generation of recombinant adenoviral vectors by Cre-lox recombination in vitro.
Molecular medicine (Cambridge, Mass.) 1999;5(4):224-31.
1999: Gary Nabel
Surviving Ebola virus infection.
Nature medicine 1999;5(4):373-4.
1999: Gary Nabel
A transformed view of cyclosporine.
Nature 1999;397(6719):471-2.
1999: Gary Nabel
Development of optimized vectors for gene therapy.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(2):324-6.
1999: S Yang; R Delgado; Steven R King; C Woffendin; C S Barker; ZY Yang; Li Xu; G P Nolan; Gary Nabel
Generation of retroviral vector for clinical studies using transient transfection.
Human gene therapy 1999;10(1):123-32.
1998: Jacques Friborg; Wing-Pui Kong; CC Flowers; S L Flowers; Y Sun; Kimberly E Foreman; Brian J Nickoloff; Gary Nabel
Distinct biology of Kaposi's sarcoma-associated herpesvirus from primary lesions and body cavity lymphomas.
Journal of virology 1998;72(12):10073-82.
1998: J J Chen; Y Sun; Gary Nabel
Regulation of the proinflammatory effects of Fas ligand (CD95L).
Science (New York, N.Y.) 1998;282(5394):1714-7.
1998: Robert D Simari; ZY Yang; X Ling; D Stephan; N D Perkins; Gary Nabel; Elizabeth G Nabel
Requirements for enhanced transgene expression by untranslated sequences from the human cytomegalovirus immediate-early gene.
Molecular medicine (Cambridge, Mass.) 1998;4(11):700-6.
1998: Xavier Danthinne; K Aoki; A L Kurachi; Gary Nabel; Elizabeth G Nabel
Combination gene delivery of the cell cycle inhibitor p27 with thymidine kinase enhances prodrug cytotoxicity.
Journal of virology 1998;72(11):9201-7.
1998: Gary Nabel; P Hobart
Keystone symposia on: molecular and cellular biology of gene therapy and synthetic non-viral gene delivery systems, Keystone, CO, USA, January 19-25, 1998.
Biochimica et biophysica acta 1998;1378(2):R19-26.
1998: SY Chan; M C Louie; JR Piccotti; Gopa V Iyer; X Ling; ZY Yang; Gary Nabel; D Keith Bishop
Genetic vaccination-induced immune responses to the human immunodeficiency virus protein Rev: emergence of the interleukin 2-producing helper T lymphocyte.
Human gene therapy 1998;9(15):2187-96.
1998: Michael Hottiger; Gary Nabel
Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.
Journal of virology 1998;72(10):8252-6.
1998: Mark D Rekhter; N Shah; RD Simari; CW Work; J S Kim; Gary Nabel; Elizabeth G Nabel; David F Gordon
Graft permeabilization facilitates gene therapy of transplant arteriosclerosis in a rabbit model.
Circulation 1998;98(13):1335-41.
1998: Anthony Sanchez; Z Y Yang; L Xu; Gary Nabel; T Crews; Clarence Peters
Biochemical analysis of the secreted and virion glycoproteins of Ebola virus.
Journal of virology 1998;72(8):6442-7.
1998: Mark D Rekhter; RD Simari; CW Work; Gary Nabel; Elizabeth G Nabel; David F Gordon
Gene transfer into normal and atherosclerotic human blood vessels.
Circulation research 1998;82(12):1243-52.
1998: CC Flowers; S P Flowers; Gary Nabel
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor confers resistance to the antiproliferative effect of interferon-alpha.
Molecular medicine (Cambridge, Mass.) 1998;4(6):402-12.
1998: Michael Hottiger; LK Felzien; Gary Nabel
Modulation of cytokine-induced HIV gene expression by competitive binding of transcription factors to the coactivator p300.
The EMBO journal 1998;17(11):3124-34.
1998: S Verma; C Woffendin; Ingrid Bahner; Udaykumar Ranga; Li Xu; ZY Yang; Steven R King; Donald B Kohn; Gary Nabel
Gene transfer into human umbilical cord blood-derived CD34+ cells by particle-mediated gene transfer.
Gene therapy 1998;5(5):692-9.
1998: Gary Nabel
Immune recognition of malignancies: relevance to immunotherapy.
The cancer journal from Scientific American 1998;4 Suppl 1():S106-11.
1998: Gary Nabel
From rhyme to reason.
Nature 1998;392(6679 Suppl):3-4.
1998: LK Felzien; C Woffendin; Michael Hottiger; R A Subbramanian; E A Cohen; Gary Nabel
HIV transcriptional activation by the accessory protein, VPR, is mediated by the p300 co-activator.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(9):5281-6.
1998: FC Tanner; ZY Yang; E Duckers; David F Gordon; Gary Nabel; Elizabeth G Nabel
Expression of cyclin-dependent kinase inhibitors in vascular disease.
Circulation research 1998;82(3):396-403.
1998: Zhenglin Yang; R Delgado; Li Xu; Robert F Todd III; Elizabeth G Nabel; A Sanchez; Gary Nabel
Distinct cellular interactions of secreted and transmembrane Ebola virus glycoproteins.
Science (New York, N.Y.) 1998;279(5353):1034-7.
1998: Udaykumar Ranga; C Woffendin; S Verma; Li Xu; C H June; D Keith Bishop; Gary Nabel
Enhanced T cell engraftment after retroviral delivery of an antiviral gene in HIV-infected individuals.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(3):1201-6.
1998: Li Xu; A Sanchez; Zhenglin Yang; S R Zaki; Elizabeth G Nabel; Stuart T Nichol; Gary Nabel
Immunization for Ebola virus infection.
Nature medicine 1998;4(1):37-42.
1997: STEVEN ROSENBERG; R. Michael Blaese; M K Brenner; A B Deisseroth; F D Ledley; M T Lotze; J M Wilson; Gary Nabel; Kenneth Cornetta; J S Economou; S M Freeman; S R Riddell; E Oldfield; B Gansbacher; Cynthia Dunbar; Robert E Walker; F G Schuening; J A Roth; R G Crystal; M J Welsh; KW Culver; H E Heslop; J Simons; R W Wilmott; R C Boucher
Human gene marker/therapy clinical protocols.
Human gene therapy 1997;8(18):2301-38.
1997: H Arai; David F Gordon; Elizabeth G Nabel; Gary Nabel
Gene transfer of Fas ligand induces tumor regression in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13862-7.
1997: Z Li; Gary Nabel
A new member of the I kappaB protein family, I kappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription.
Molecular and cellular biology 1997;17(10):6184-90.
1997: FC Tanner; D P Carr; Gary Nabel; Elizabeth G Nabel
Transfection of human endothelial cells.
Cardiovascular research 1997;35(3):522-8.
1997: D Stephan; Hong San; ZY Yang; David F Gordon; S Goelz; Gary Nabel; Elizabeth G Nabel
Inhibition of vascular smooth muscle cell proliferation and intimal hyperplasia by gene transfer of beta-interferon.
Molecular medicine (Cambridge, Mass.) 1997;3(9):593-9.
1997: Udaykumar Ranga; C Woffendin; ZY Yang; Li Xu; S Verma; Dan R Littman; Gary Nabel
Cell and viral regulatory elements enhance the expression and function of a human immunodeficiency virus inhibitory gene.
Journal of virology 1997;71(9):7020-9.
1997: D Stephan; B Gasser; Hong San; M Schubnel; Gary Nabel; Elizabeth G Nabel
[Direct gene transfer in the rat kidney in vivo].
Archives des maladies du coeur et des vaisseaux 1997;90(8):1127-30.
1997: D Stephan; Hong San; David F Gordon; Gary Nabel; Elizabeth G Nabel
[Gene transfer of interferon beta inhibits vascular smooth muscle cell proliferation in vitro and in animal model of arterial injury].
Archives des maladies du coeur et des vaisseaux 1997;90(8):1121-5.
1997: H Arai; SY Chan; D Keith Bishop; Gary Nabel
Inhibition of the alloantibody response by CD95 ligand.
Nature medicine 1997;3(8):843-8.
1997: David M Rodman; Hong San; R Simari; D Stephan; FC Tanner; Z Yang; Gary Nabel; Elizabeth G Nabel
In vivo gene delivery to the pulmonary circulation in rats: transgene distribution and vascular inflammatory response.
American journal of respiratory cell and molecular biology 1997;16(6):640-9.
1997: Elizabeth G Nabel; R Simari; Z Yang; Hong San; Gary Nabel
In vivo gene transfer: a biological tool.
Annals of the New York Academy of Sciences 1997;811():289-92.
1997: T Ohno; Z Yang; X Ling; M Jaffe; Elizabeth G Nabel; Daniel Normolle; Gary Nabel
Combination gene transfer to potentiate tumor regression.
Gene therapy 1997;4(4):361-6.
1997: B Y Wu; C Woffendin; I MacLachlan; Gary Nabel
Distinct domains of IkappaB-alpha inhibit human immunodeficiency virus type 1 replication through NF-kappaB and Rev.
Journal of virology 1997;71(4):3161-7.
1997: CC Flowers; C Woffendin; Jerzy Petryniak; S Yang; Gary Nabel
Inhibition of recombinant human immunodeficiency virus type 1 replication by a site-specific recombinase.
Journal of virology 1997;71(4):2685-92.
1997: Arul M Chinnaiyan; C Woffendin; V M Dixit; Gary Nabel
The inhibition of pro-apoptotic ICE-like proteases enhances HIV replication.
Nature medicine 1997;3(3):333-7.
1997: S F Parker; LK Felzien; N D Perkins; Michael J Imperiale; Gary Nabel
Distinct domains of adenovirus E1A interact with specific cellular factors to differentially modulate human immunodeficiency virus transcription.
Journal of virology 1997;71(3):2004-12.
1997: N D Perkins; LK Felzien; J C Betts; K Leung; D H Beach; Gary Nabel
Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator.
Science (New York, N.Y.) 1997;275(5299):523-7.
1997: Kimberly E Foreman; Jacques Friborg; Wing-Pui Kong; C Woffendin; Peter J Polverini; Brian J Nickoloff; Gary Nabel
Propagation of a human herpesvirus from AIDS-associated Kaposi's sarcoma.
The New England journal of medicine 1997;336(3):163-71.
1996: Gary Nabel; David F Gordon; D Keith Bishop; Brian J Nickoloff; ZY Yang; Atsushi Aruga; Mark Cameron; Elizabeth G Nabel; Alfred E Chang
Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(26):15388-93.
1996: STEVEN ROSENBERG; R. Michael Blaese; M K Brenner; A B Deisseroth; F D Ledley; M T Lotze; J M Wilson; Gary Nabel; Kenneth Cornetta; J S Economou; SM Freeman; S R Riddell; E Oldfield; B Gansbacher; Cynthia Dunbar; Robert E Walker; F G Schuening; J A Roth; Helen-Ann Brown Epstein; M J Welsh; KW Culver; H E Heslop; J Simons; R W Wilmott; P Tiberghien
Human gene marker/therapy clinical protocols.
Human gene therapy 1996;7(18):2287-313.
1996: M L Jaffe; H Arai; Gary Nabel
Mechanisms of tumor-induced immunosuppression: evidence for contact-dependent T cell suppression by monocytes.
Molecular medicine (Cambridge, Mass.) 1996;2(6):692-701.
1996: J C Betts; Gary Nabel
Differential regulation of NF-kappaB2(p100) processing and control by amino-terminal sequences.
Molecular and cellular biology 1996;16(11):6363-71.
1996: D J Stephan; ZY Yang; Hong San; Robert D Simari; C J Wheeler; Philip L Felgner; David F Gordon; Gary Nabel; Elizabeth G Nabel
A new cationic liposome DNA complex enhances the efficiency of arterial gene transfer in vivo.
Human gene therapy 1996;7(15):1803-12.
1996: Z Yang; Robert D Simari; FC Tanner; D Stephan; Gary Nabel; Elizabeth G Nabel
Gene transfer approaches to the regulation of vascular cell proliferation.
Seminars in interventional cardiology : SIIC 1996;1(3):181-4.
1996: LA Debruyne; Alfred E Chang; Mark Cameron; Z Yang; David F Gordon; Elizabeth G Nabel; Gary Nabel; D Keith Bishop
Direct transfer of a foreign MHC gene into human melanoma alters T cell receptor V beta usage by tumor-infiltrating lymphocytes.
Cancer immunology, immunotherapy : CII 1996;43(1):49-58.
1996: STEVEN ROSENBERG; R. Michael Blaese; M K Brenner; A B Deisseroth; F D Ledley; M T Lotze; J M Wilson; Gary Nabel; Kenneth Cornetta; J S Economou; SM Freeman; S R Riddell; E Oldfield; B Gansbacher; Cynthia Dunbar; Robert E Walker; F G Schuening; J A Roth; Helen-Ann Brown Epstein; M J Welsh; KW Culver; H E Heslop; J Simons; R W Wilmott; P Aebischer
Human gene marker/therapy clinical protocols.
Human gene therapy 1996;7(13):1621-47.
1996: S F Parker; N D Perkins; Scott D Gitlin; Gary Nabel
A cooperative interaction of human T-cell leukemia virus type 1 Tax with the p21 cyclin-dependent kinase inhibitor activates the human immunodeficiency virus type 1 enhancer.
Journal of virology 1996;70(8):5731-4.
1996: ZY Yang; Robert D Simari; N D Perkins; Hong San; David F Gordon; Gary Nabel; Elizabeth G Nabel
Role of the p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7905-10.
1996: Robert D Simari; Hong San; Mark D Rekhter; T Ohno; David F Gordon; Gary Nabel; Elizabeth G Nabel
Regulation of cellular proliferation and intimal formation following balloon injury in atherosclerotic rabbit arteries.
The Journal of clinical investigation 1996;98(1):225-35.
1996: C Woffendin; Udaykumar Ranga; Z Yang; Li Xu; Gary Nabel
Expression of a protective gene-prolongs survival of T cells in human immunodeficiency virus-infected patients.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2889-94.
1996: Gary Nabel; C Grunfeld
Calories lost--another mediator of cancer cachexia?
Nature medicine 1996;2(4):397-8.
1995: V J Pompili; David F Gordon; Hong San; Z Yang; D W Muller; Gary Nabel; Elizabeth G Nabel
Expression and function of a recombinant PDGF B gene in porcine arteries.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(12):2254-64.
1995: Gary Nabel; ZY Yang; Elizabeth G Nabel; D Keith Bishop; M Marquet; P L Felgner; David F Gordon; Alfred E Chang
Direct gene transfer for treatment of human cancer.
Annals of the New York Academy of Sciences 1995;772():227-31.
1995: Z Y Yang; N D Perkins; T Ohno; Elizabeth G Nabel; Gary Nabel
The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo.
Nature medicine 1995;1(10):1052-6.
1995: Colin S Duckett; N D Perkins; K Leung; A B Agranoff; Gary Nabel
Cytokine induction of nuclear factor kappa B in cycling and growth-arrested cells. Evidence for cell cycle-independent activation.
The Journal of biological chemistry 1995;270(32):18836-40.
1995: Fox Bernard; C Woffendin; ZY Yang; Hong San; Udaykumar Ranga; David F Gordon; John Osterholzer; Gary Nabel
Genetic modification of human peripheral blood lymphocytes with a transdominant negative form of Rev: safety and toxicity.
Human gene therapy 1995;6(8):997-1004.
1995: Antonio Gualberto; Mary L Hixon; T S Finco; N D Perkins; Gary Nabel; Albert S Baldwin
A proliferative p53-responsive element mediates tumor necrosis factor alpha induction of the human immunodeficiency virus type 1 long terminal repeat.
Molecular and cellular biology 1995;15(6):3450-9.
1995: Gary Nabel
The MD PhD physician scientist--endangered species or the next generation?
Molecular medicine (Cambridge, Mass.) 1995;1(4):369-70.
1995: D Lew; SE Parker; T Latimer; Anna Maria Abai; A Kuwahara-Rundell; S G Doh; Z Y Yang; D Laface; S H Gromkowski; Gary Nabel
Cancer gene therapy using plasmid DNA: pharmacokinetic study of DNA following injection in mice.
Human gene therapy 1995;6(5):553-64.
1995: B Y Wu; C Woffendin; Colin S Duckett; T Ohno; Gary Nabel
Regulation of human retroviral latency by the NF-kappa B/I kappa B family: inhibition of human immunodeficiency virus replication by I kappa B through a Rev-dependent mechanism.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1480-4.
1995: M W Chang; E Barr; J Seltzer; Y Q Jiang; Gary Nabel; Elizabeth G Nabel; Michael S Parmacek; Jeffrey M Leiden
Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product.
Science (New York, N.Y.) 1995;267(5197):518-22.
1995: M W Chang; T Ohno; David F Gordon; Min Min Lu; Gary Nabel; Elizabeth G Nabel; Jeffrey M Leiden
Adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene inhibits vascular smooth muscle cell proliferation and neointima formation following balloon angioplasty of the rat carotid artery.
Molecular medicine (Cambridge, Mass.) 1995;1(2):172-81.
1995: Wendy L Wahl; Scott E Strome; Gary Nabel; Gregory E Plautz; Mark Cameron; Hong San; Fox Bernard; Suyu Shu; Alfred E Chang
Generation of therapeutic T-lymphocytes after in vivo tumor transfection with an allogeneic class I major histocompatibility complex gene.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1995;17(1):1-11.
1994: Roland M Schmid; Susanne Liptay; J C Betts; Gary Nabel
Structural and functional analysis of NF-kappa B. Determinants of DNA binding specificity and protein interaction.
The Journal of biological chemistry 1994;269(51):32162-7.
1994: Susanne Liptay; Roland M Schmid; Elizabeth G Nabel; Gary Nabel
Transcriptional regulation of NF-kappa B2: evidence for kappa B-mediated positive and negative autoregulation.
Molecular and cellular biology 1994;14(12):7695-703.
1994: D W Muller; David F Gordon; Hong San; Z Yang; V J Pompili; Gary Nabel; Elizabeth G Nabel
Catheter-mediated pulmonary vascular gene transfer and expression.
Circulation research 1994;75(6):1039-49.
1994: C Woffendin; ZY Yang; Li Xu; Ning-Sun Yang; M J Sheehy; Gary Nabel
Nonviral and viral delivery of a human immunodeficiency virus protective gene into primary human T cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11581-5.
1994: N D Perkins; A B Agranoff; Colin S Duckett; Gary Nabel
Transcription factor AP-2 regulates human immunodeficiency virus type 1 gene expression.
Journal of virology 1994;68(10):6820-3.
1994: N D Perkins; A B Agranoff; E Pascal; Gary Nabel
An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation.
Molecular and cellular biology 1994;14(10):6570-83.
1994: Elizabeth G Nabel; Z Yang; D Muller; Alfred E Chang; Xiang Gao; L Huang; Kyung J Cho; Gary Nabel
Safety and toxicity of catheter gene delivery to the pulmonary vasculature in a patient with metastatic melanoma.
Human gene therapy 1994;5(9):1089-94.
1994: T Ohno; David F Gordon; Hong San; V J Pompili; Michael J Imperiale; Gary Nabel; Elizabeth G Nabel
Gene therapy for vascular smooth muscle cell proliferation after arterial injury.
Science (New York, N.Y.) 1994;265(5173):781-4.
1994: Gregory E Plautz; Elizabeth G Nabel; B Fox; ZY Yang; M Jaffe; David F Gordon; Alfred E Chang; Gary Nabel
Direct gene transfer for the understanding and treatment of human disease.
Annals of the New York Academy of Sciences 1994;716():144-53.
1994: Lizhi Zhang; Gary Nabel
Positive and negative regulation of IL-2 gene expression: role of multiple regulatory sites.
Cytokine 1994;6(3):221-8.
1994: Elizabeth G Nabel; Gregory E Plautz; Gary Nabel
Recombinant growth factor gene expression in vascular cells in vivo.
Annals of the New York Academy of Sciences 1994;714():247-52.
1994: Elizabeth G Nabel; V J Pompili; Gregory E Plautz; Gary Nabel
Gene transfer and vascular disease.
Cardiovascular research 1994;28(4):445-55.
1994: M C Hannibal; David M Markovitz; Gary Nabel
Multiple cis-acting elements in the human immunodeficiency virus type 2 enhancer mediate the response to T-cell receptor stimulation by antigen in a T-cell hybridoma line.
Blood 1994;83(7):1839-46.
1994: J C Betts; A B Agranoff; Gary Nabel; James A Shayman
Dissociation of endogenous cellular ceramide from NF-kappa B activation.
The Journal of biological chemistry 1994;269(11):8455-8.
1994: K Leung; J C Betts; L Xu; Gary Nabel
The cytoplasmic domain of the interleukin-1 receptor is required for nuclear factor-kappa B signal transduction.
The Journal of biological chemistry 1994;269(3):1579-82.
1994: Gary Nabel; Fox Bernard; L Post; Craig Thompson; C Woffendin
A molecular genetic intervention for AIDS--effects of a transdominant negative form of Rev.
Human gene therapy 1994;5(1):79-92.
1994: Gary Nabel; Alfred E Chang; Elizabeth G Nabel; Gregory E Plautz; William D Ensminger; Fox Bernard; Philip L Felgner; Suyu Shu; Kyung J Cho
Immunotherapy for cancer by direct gene transfer into tumors.
Human gene therapy 1994;5(1):57-77.
1994: Elizabeth G Nabel; Gary Nabel
Complex models for the study of gene function in cardiovascular biology.
Annual review of physiology 1994;56():741-61.
1994: Gary Nabel; Elizabeth G Nabel; Z Yang; Fox Bernard; Gregory E Plautz; Xiang Gao; L Huang; Suyu Shu; David F Gordon; Alfred E Chang
Molecular genetic interventions for cancer.
Cold Spring Harbor symposia on quantitative biology 1994;59():699-707.
1994: J Liu; C Woffendin; ZY Yang; Gary Nabel
Regulated expression of a dominant negative form of Rev improves resistance to HIV replication in T cells.
Gene therapy 1994;1(1):32-7.
1993: Gary Nabel; Elizabeth G Nabel; ZY Yang; Fox Bernard; Gregory E Plautz; Xiang Gao; L Huang; Suyu Shu; David F Gordon; Alfred E Chang
Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11307-11.
1993: Gary Nabel; Inder M Verma
Proposed NF-kappa B/I kappa B family nomenclature.
Genes & development 1993;7(11):2063.
1993: S L Eck; N D Perkins; D P Carr; Gary Nabel
Inhibition of phorbol ester-induced cellular adhesion by competitive binding of NF-kappa B in vivo.
Molecular and cellular biology 1993;13(10):6530-6.
1993: H B Shu; A B Agranoff; Elizabeth G Nabel; K Leung; Colin S Duckett; A S Neish; T Collins; Gary Nabel
Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-kappa B subunits in endothelial and epithelial cells.
Molecular and cellular biology 1993;13(10):6283-9.
1993: D A Potter; C J Larson; P Eckes; R M Schmid; Gary Nabel; Gregory L Verdine; Phillip A Sharp
Purification of the major histocompatibility complex class I transcription factor H2TF1. The full-length product of the nfkb2 gene.
The Journal of biological chemistry 1993;268(25):18882-90.
1993: N D Perkins; N L Edwards; Colin S Duckett; A B Agranoff; Roland M Schmid; Gary Nabel
A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation.
The EMBO journal 1993;12(9):3551-8.
1993: M C Hannibal; David M Markovitz; Nina M Clark; Gary Nabel
Differential activation of human immunodeficiency virus type 1 and 2 transcription by specific T-cell activation signals.
Journal of virology 1993;67(8):5035-40.
1993: Salvatore T Butera; BD Roberts; K Leung; Gary Nabel; Thomas M Folks
Tumor necrosis factor receptor expression and signal transduction in HIV-1-infected cells.
AIDS (London, England) 1993;7(7):911-8.
1993: Elizabeth G Nabel; Gary Nabel
Direct gene transfer: basic studies and human therapies.
Thrombosis and haemostasis 1993;70(1):202-3.
1993: Gregory E Plautz; ZY Yang; B Y Wu; Xiang Gao; L Huang; Gary Nabel
Immunotherapy of malignancy by in vivo gene transfer into tumors.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(10):4645-9.
1993: Gary Nabel; P L Felgner
Direct gene transfer for immunotherapy and immunization.
Trends in biotechnology 1993;11(5):211-5.
1993: Elizabeth G Nabel; ZY Yang; Gregory E Plautz; R Forough; Steven Zhan; Christian Haudenschild; Thomas Maciag; Gary Nabel
Recombinant fibroblast growth factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo.
Nature 1993;362(6423):844-6.
1993: Elizabeth G Nabel; Z Yang; Susanne Liptay; Hong San; David F Gordon; Christian Haudenschild; Gary Nabel
Recombinant platelet-derived growth factor B gene expression in porcine arteries induce intimal hyperplasia in vivo.
The Journal of clinical investigation 1993;91(4):1822-9.
1993: Colin S Duckett; N D Perkins; T F Kowalik; Roland M Schmid; Eng-Shang Huang; Albert S Baldwin; Gary Nabel
Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3).
Molecular and cellular biology 1993;13(3):1315-22.
1992: Elizabeth G Nabel; David F Gordon; ZY Yang; Li Xu; Hong San; Gregory E Plautz; B Y Wu; Xiang Gao; L Huang; Gary Nabel
Gene transfer in vivo with DNA-liposome complexes: lack of autoimmunity and gonadal localization.
Human gene therapy 1992;3(6):649-56.
1992: L D Kerr; Colin S Duckett; P Wamsley; Q Zhang; P Chiao; Gary Nabel; T W McKeithan; P A Baeuerle; Inder M Verma
The proto-oncogene bcl-3 encodes an I kappa B protein.
Genes & development 1992;6(12A):2352-63.
1992: B Y Wu; E W Hanley; Laurence A Turka; Gary Nabel
Isolation of a cDNA clone encoding a zinc finger protein highly expressed in T-leukemia lines.
Blood 1992;80(10):2571-6.
1992: A R Freedman; R J Sharma; Gary Nabel; S G Emerson; George E Griffin
Cellular distribution of nuclear factor kappa B binding activity in rat liver.
The Biochemical journal 1992;287 ( Pt 2)():645-9.
1992: Jeffrey M Leiden; C Y Wang; B Petryniak; David M Markovitz; Gary Nabel; Craig Thompson
A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells.
Journal of virology 1992;66(10):5890-7.
1992: Barbara S Adams; K Leung; Paul S Meltzer; K A Lewis; C Wagner-McPherson; G A Evans; Gary Nabel
Localization of the gene encoding R kappa B (NFRKB), a tissue-specific DNA binding protein, to chromosome 11q24-q25.
Genomics 1992;14(2):270-4.
1992: Michael H Malim; W W Freimuth; J Liu; T J Boyle; H K Lyerly; Bryan R Cullen; Gary Nabel
Stable expression of transdominant Rev protein in human T cells inhibits human immunodeficiency virus replication.
The Journal of experimental medicine 1992;176(4):1197-201.
1992: David M Markovitz; M J Smith; John M Hilfinger; M C Hannibal; B Petryniak; Gary Nabel
Activation of the human immunodeficiency virus type 2 enhancer is dependent on purine box and kappa B regulatory elements.
Journal of virology 1992;66(9):5479-84.
1992: M J Stewart; Gregory E Plautz; L Del Buono; ZY Yang; Li Xu; Xiang Gao; L Huang; Elizabeth G Nabel; Gary Nabel
Gene transfer in vivo with DNA-liposome complexes: safety and acute toxicity in mice.
Human gene therapy 1992;3(3):267-75.
1992: Susanne Liptay; Roland M Schmid; N D Perkins; Paul Meltzer; M R Altherr; J D McPherson; JJ Wasmuth; Gary Nabel
Related subunits of NF-kappa B map to two distinct loci associated with translocations in leukemia, NFKB1 and NFKB2.
Genomics 1992;13(2):287-92.
1992: Elizabeth G Nabel; Gregory E Plautz; Gary Nabel
Transduction of a foreign histocompatibility gene into the arterial wall induces vasculitis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):5157-61.
1992: J Liu; N D Perkins; Roland M Schmid; Gary Nabel
Specific NF-kappa B subunits act in concert with Tat to stimulate human immunodeficiency virus type 1 transcription.
Journal of virology 1992;66(6):3883-7.
1992: David M Markovitz; M C Hannibal; M J Smith; R Cossman; Gary Nabel
Activation of the human immunodeficiency virus type 1 enhancer is not dependent on NFAT-1.
Journal of virology 1992;66(6):3961-5.
1992: Craig Thompson; C Y Wang; I C Ho; P R Bohjanen; B Petryniak; Carl H June; Susan Miesfeldt; L Zhang; Gary Nabel; B Karpinski
cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.
Molecular and cellular biology 1992;12(3):1043-53.
1992: N D Perkins; Roland M Schmid; Colin S Duckett; K Leung; N R Rice; Gary Nabel
Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1529-33.
1991: S L Eck; Gary Nabel
Antisense oligonucleotides for therapeutic intervention.
Current opinion in biotechnology 1991;2(6):897-904.
1991: Barbara S Adams; K Y Leung; E W Hanley; Gary Nabel
Cloning of R kappa B, a novel DNA-binding protein that recognizes the interleukin-2 receptor alpha chain kappa B site.
The New biologist 1991;3(11):1063-73.
1991: S W Krasnow; L Q Zhang; K Y Leung; L Osborn; Steven Kunkel; Gary Nabel
Tumor necrosis factor-alpha, interleukin 1, and phorbol myristate acetate are independent activators of NF-kappa B which differentially activate T cells.
Cytokine 1991;3(5):372-9.
1991: Salvatore T Butera; V L Perez; B Y Wu; Gary Nabel; Thomas M Folks
Oscillation of the human immunodeficiency virus surface receptor is regulated by the state of viral activation in a CD4+ cell model of chronic infection.
Journal of virology 1991;65(9):4645-53.
1991: Roland M Schmid; N D Perkins; Colin S Duckett; Philip C Andrews; Gary Nabel
Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65.
Nature 1991;352(6337):733-6.
1991: L J Baier; M C Hannibal; E W Hanley; Gary Nabel
Lymphoid expression and TATAA binding of a human protein containing an Antennapedia homeodomain.
Blood 1991;78(4):1047-55.
1991: Gregory E Plautz; Elizabeth G Nabel; Gary Nabel
Selective elimination of recombinant genes in vivo with a suicide retroviral vector.
The New biologist 1991;3(7):709-15.
1991: Elizabeth G Nabel; Gregory E Plautz; Gary Nabel
Gene transfer into vascular cells.
Journal of the American College of Cardiology 1991;17(6 Suppl B):189B-194B.
1991: Gary Nabel
HIV. Tampering with transcription.
Nature 1991;350(6320):658.
1991: Salvatore T Butera; V L Perez; N J Besansky; W C Chan; B Y Wu; Gary Nabel; Thomas M Folks
Extrachromosomal human immunodeficiency virus type-1 DNA can initiate a spreading infection of HL-60 cells.
Journal of cellular biochemistry 1991;45(4):366-73.
1991: George E Griffin; K Leung; Thomas M Folks; Steven Kunkel; Gary Nabel
Induction of NF-kappa B during monocyte differentiation is associated with activation of HIV-gene expression.
Research in virology 1991;142(2-3):233-8.
1991: Anna U Bielinska; L Baier; N Hailat; J R Strahler; Gary Nabel; S Hanash
Expression of a novel nuclear protein in activated and in tat-I expressing T cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(3):1031-6.
1991: Gregory E Plautz; Elizabeth G Nabel; Gary Nabel
Introduction of vascular smooth muscle cells expressing recombinant genes in vivo.
Circulation 1991;83(2):578-83.
1991: Elizabeth G Nabel; Gary Nabel
Gene transfer and cardiovascular disease.
Trends in cardiovascular medicine 1991;1(1):12-7.
1990: David M Markovitz; M Hannibal; V L Perez; C Gauntt; Thomas M Folks; Gary Nabel
Differential regulation of human immunodeficiency viruses (HIVs): a specific regulatory element in HIV-2 responds to stimulation of the T-cell antigen receptor.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(23):9098-102.
1990: Anna U Bielinska; Ramesh A Shivdasani; L Q Zhang; Gary Nabel
Regulation of gene expression with double-stranded phosphorothioate oligonucleotides.
Science (New York, N.Y.) 1990;250(4983):997-1000.
1990: Elizabeth G Nabel; Gregory E Plautz; Gary Nabel
Site-specific gene expression in vivo by direct gene transfer into the arterial wall.
Science (New York, N.Y.) 1990;249(4974):1285-8.
1989: W W Freimuth; J M Depper; Gary Nabel
Regulation of the IL-2 receptor alpha-gene. Interaction of a kappa B binding protein with cell-specific transcription factors.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(9):3064-8.
1989: Anna U Bielinska; S Krasnow; Gary Nabel
NF-kappa B-mediated activation of the human immunodeficiency virus enhancer: site of transcriptional initiation is independent of the TATA box.
Journal of virology 1989;63(9):4097-100.
1989: Elizabeth G Nabel; Gregory E Plautz; F M Boyce; James C Stanley; Gary Nabel
Recombinant gene expression in vivo within endothelial cells of the arterial wall.
Science (New York, N.Y.) 1989;244(4910):1342-4.
1989: G E Griffin; K Leung; Thomas M Folks; Steven Kunkel; Gary Nabel
Activation of HIV gene expression during monocyte differentiation by induction of NF-kappa B.
Nature 1989;339(6219):70-3.
1989: L Osborn; Steven Kunkel; Gary Nabel
Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2336-40.
1988: K Leung; Gary Nabel
HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-kappa B-like factor.
Nature 1988;333(6175):776-8.
1988: Gary Nabel
Activation of human immunodeficiency virus.
The Journal of laboratory and clinical medicine 1988;111(5):495-500.
1988: Gary Nabel; C Gorka; David Baltimore
T-cell-specific expression of interleukin 2: evidence for a negative regulatory site.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(9):2934-8.
1988: Gary Nabel; S A Rice; D M Knipe; David Baltimore
Alternative mechanisms for activation of human immunodeficiency virus enhancer in T cells.
Science (New York, N.Y.) 1988;239(4845):1299-302.
1987: Gary Nabel; David Baltimore
An inducible transcription factor activates expression of human immunodeficiency virus in T cells.
Nature 1987;326(6114):711-3.
1986: B Mathey-Prevot; Gary Nabel; R Palacios; David Baltimore
Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line.
Molecular and cellular biology 1986;6(11):4133-5.
1986: D C Seldin; J P Caulfield; A Hein; R Osathanondh; Gary Nabel; S F Schlossman; R L Stevens; K F Austen
Biochemical and phenotypic characterization of human basophilic cells derived from dispersed fetal liver with murine T cell factors.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(6):2222-30.
1985: Gary Nabel
Order and human biology.
The American journal of medicine 1985;78(4):545-8.
1985: D M Rennick; F D Lee; T Yokota; K I Arai; Harvey Cantor; Gary Nabel
A cloned MCGF cDNA encodes a multilineage hematopoietic growth factor: multiple activities of interleukin 3.
Journal of immunology (Baltimore, Md. : 1950) 1985;134(2):910-4.
1984: E Razin; R L Stevens; K F Austen; J P Caulfield; A Hein; Fu-Tong Liu; M Clabby; Gary Nabel; Harvey Cantor; S Friedman
Cloned mouse mast cells derived from immunized lymph node cells and from foetal liver cells exhibit characteristics of bone marrow-derived mast cells containing chondroitin sulphate E proteoglycan.
Immunology 1984;52(3):563-75.
1984: T Yokota; F Lee; Donna Rennick; C Hall; N Arai; T Mosmann; Gary Nabel; Harvey Cantor; K Arai
Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(4):1070-4.
1983: J S Greenberger; R J Eckner; M Sakakeeny; P Marks; D Reid; Gary Nabel; A Hapel; J N Ihle; K C Humphries
Interleukin 3-dependent hematopoietic progenitor cell lines.
Federation proceedings 1983;42(10):2762-71.
1983: A M Dvorak; S J Galli; J A Marcum; Gary Nabel; H der Simonian; J Goldin; R A Monahan; K Pyne; Harvey Cantor; R D Rosenberg; H F Dvorak
Cloned mouse cells with natural killer function and cloned suppressor T cells express ultrastructural and biochemical features not shared by cloned inducer T cells.
The Journal of experimental medicine 1983;157(3):843-61.
1983: S J Galli; A M Dvorak; J A Marcum; Gary Nabel; J M Goldin; R D Rosenberg; Harvey Cantor; H F Dvorak
Mouse mast cell clones: modulation of functional maturity in vitro.
Monographs in allergy 1983;18():166-70.
1982: S J Galli; A M Dvorak; J A Marcum; TERUKO ISHIZAKA; Gary Nabel; H Der Simonian; K Pyne; J M Goldin; R D Rosenberg; Harvey Cantor; H F Dvorak
Mast cell clones: a model for the analysis of cellular maturation.
The Journal of cell biology 1982;95(2 Pt 1):435-44.
1982: M Fresno; H Der Simonian; Gary Nabel; Harvey Cantor
Proteins synthesized by inducer T cells: evidence for a mitogenic peptide shared by inducer molecules that stimulate different cell types.
Cell 1982;30(3):707-13.
1982: Gary Nabel; W J Allard; Harvey Cantor
A cloned cell line mediating natural killer cell function inhibits immunoglobulin secretion.
The Journal of experimental medicine 1982;156(2):658-63.
1982: S J Galli; A M Dvorak; TERUKO ISHIZAKA; Gary Nabel; H Der Simonian; Harvey Cantor; H F Dvorak
A cloned cell with NK function resembles basophils by ultrastructure and expresses IgE receptors.
Nature 1982;298(5871):288-90.
1982: A M Dvorak; Gary Nabel; K Pyne; Harvey Cantor; H F Dvorak; S J Galli
Ultrastructural identification of the mouse basophil.
Blood 1982;59(6):1279-85.
1981: Gary Nabel; L R Bucalo; J Allard; H Wigzell; Harvey Cantor
Multiple activities of a cloned cell line mediating natural killer cell function.
The Journal of experimental medicine 1981;153(6):1582-91.
1981: Gary Nabel; S J Galli; A M Dvorak; H F Dvorak; Harvey Cantor
Inducer T lymphocytes synthesize a factor that stimulates proliferation of cloned mast cells.
Nature 1981;291(5813):332-4.
1981: M Fresno; L McVay-Boudreau; Gary Nabel; Harvey Cantor
Antigen-specific T lymphocyte clones. II. Purification and biological characterization of an antigen-specific suppressive protein synthesized by cloned T cells.
The Journal of experimental medicine 1981;153(5):1260-74.
1981: M Fresno; Gary Nabel; L McVay-Boudreau; H Furthmayer; Harvey Cantor
Antigen-specific T lymphocyte clones. I. Characterization of a T lymphocyte clone expressing antigen-specific suppressive activity.
The Journal of experimental medicine 1981;153(5):1246-59.
1981: M Fresno; L Mc-Vay Boudreau; Gary Nabel; Harvey Cantor
Biologic properties of a purified antigen-specific suppressive glycopeptide.
Transplantation proceedings 1981;13(1 Pt 2):1124-7.
1981: Gary Nabel; J S Greenberger; M A Sakakeeny; Harvey Cantor
Multiple biologic activities of a cloned inducer T-cell population.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(2):1157-61.
1981: Gary Nabel; M Fresno; A Chessman; Harvey Cantor
Use of cloned populations of mouse lymphocytes to analyze cellular differentiation.
Cell 1981;23(1):19-28.