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William Paul

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Marina Harvie; Mali Camberis; Shiau-Choot Tang; Brett Delahunt; William Paul; Graham Le Gros
The lung is an important site for priming CD4 T-cell-mediated protective immunity against gastrointestinal helminth parasites.
Liying Guo; Gang Wei; Jinfang Zhu; Wei Liao; Warren J Leonard; Keji Zhao; William Paul
IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells.
Shane R Horman; Chinavenmeni S Velu; Aditya Chaubey; Tristan Bourdeau; Jinfang Zhu; William Paul; Brian Gebelein; H Leighton Grimes
Gfi1 integrates progenitor versus granulocytic transcriptional programming.

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All Publications

2010: Marina Harvie; Mali Camberis; Shiau-Choot Tang; Brett Delahunt; William Paul; Graham Le Gros
The lung is an important site for priming CD4 T-cell-mediated protective immunity against gastrointestinal helminth parasites.
Infection and immunity 2010;78(9):3753-62.
2009: Liying Guo; Gang Wei; Jinfang Zhu; Wei Liao; Warren J Leonard; Keji Zhao; William Paul
IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(32):13463-8.
2009: Shane R Horman; Chinavenmeni S Velu; Aditya Chaubey; Tristan Bourdeau; Jinfang Zhu; William Paul; Brian Gebelein; H Leighton Grimes
Gfi1 integrates progenitor versus granulocytic transcriptional programming.
Blood 2009;113(22):5466-75.
2009: Shlomo Z Ben-Sasson; Jane Hu-Li; Juan Quiel; Stephane Cauchetaux; Maya Ratner; Ilan Shapira; Charles A Dinarello; William Paul
IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(17):7119-24.
2009: Jinfang Zhu; Todd S Davidson; Gang Wei; Dragana Jankovic; Kairong Cui; Dustin E Schones; Liying Guo; Keji Zhao; Ethan M Shevach; William Paul
Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.
The Journal of experimental medicine 2009;206(2):329-41.
2009: Gang Wei; Lai Wei; Jinfang Zhu; Chongzhi Zang; Jane Hu-Li; Zhengju Yao; Kairong Cui; Yuka Kanno; Tae-Young Roh; Wendy T Watford; Dustin E Schones; Weiqun Peng; Hong-Wei Sun; William Paul; John O'Shea; Keji Zhao
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells.
Immunity 2009;30(1):155-67.
2008: Wendy T Watford; Bruce D Hissong; Lydia Durant; Hidehiro Yamane; Linda Muul; Yuka Kanno; Cristina M Tato; Haydeé L Ramos; Alan E Berger; Lisa Mielke; Marko Pesu; Benjamin Solomon; David M Frucht; William Paul; Alan Sher; Dragana Jankovic; Philip Tsichlis; John O'Shea
Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii.
The Journal of experimental medicine 2008;205(12):2803-12.
2008: Joshua Milner; William Paul
Limited T-cell receptor diversity predisposes to Th2 immunopathology: involvement of Tregs and conventional CD4 T cells.
Journal of clinical immunology 2008;28(6):631-4.
2008: Ilkka S Junttila; Kiyoshi Mizukami; Harold Dickensheets; Martin Meier-Schellersheim; Hidehiro Yamane; Raymond P Donnelly; William Paul
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity.
The Journal of experimental medicine 2008;205(11):2595-608.
2008: William Paul
Th1 fate determination in CD4+ T cells: notice is served of the importance of IL-12!
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4435-6.
2008: Lie Wang; Kathryn F Wildt; Jinfang Zhu; Xianyu Zhang; Lionel Feigenbaum; Lino Tessarollo; William Paul; B J Fowlkes; Rémy Bosselut
Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells.
Nature immunology 2008;9(10):1122-30.
2008: Liying Guo; Joseph F Urban; Jinfang Zhu; William Paul
Elevating calcium in Th2 cells activates multiple pathways to induce IL-4 transcription and mRNA stabilization.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):3984-93.
2008: Jinfang Zhu; William Paul
CD4 T cells: fates, functions, and faults.
Blood 2008;112(5):1557-69.
2008: Graham Le Gros; Shlomo Z Ben-Sasson; Robert Seder; Fred D Finkelman; William Paul
Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(5):2943-51.
2008: Nicholas van Panhuys; Shiau-Choot Tang; Melanie Prout; Mali Camberis; Debbie Scarlett; Joanna Roberts; Jane Hu-Li; William Paul; Graham Le Gros
In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(34):12423-8.
2008: Anmol Chandele; Nikhil S Joshi; Jinfang Zhu; William Paul; Warren J Leonard; Susan M Kaech
Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(8):5309-19.
2008: Joshua D Milner; Jason M Brenchley; Arian Dominic John laurence; Alexandra F Freeman; Brenna J Hill; Kevin M Elias; Yuka Kanno; Christine Spalding; Houda Z Elloumi; Michelle L Paulson; Joie Davis; Amy Hsu; Ava I Asher; John O'Shea; Steven M Holland; William Paul; Daniel C Douek
Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome.
Nature 2008;452(7188):773-6.
2008: Booki Min; William Paul
Basophils: in the spotlight at last.
Nature immunology 2008;9(3):223-5.
2008: Nicola M Heller; Xiulan Qi; Ilkka S Junttila; Kari Ann Shirey; Stefanie N Vogel; William Paul; Achsah D Keegan
Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages.
Science signaling 2008;1(51):ra17.
2008: William Paul
Multichain immune recognition receptor signaling from spatiotemporal organization to human disease. Foreword.
Advances in experimental medicine and biology 2008;640():vii-viii.
2008: Booki Min; William Paul
Basophils and type 2 immunity.
Current opinion in hematology 2008;15(1):59-63.
2007: Joshua Milner; Jerrold Ward; Andrea Keane-Myers; Booki Min; William Paul
Repertoire-dependent immunopathology.
Journal of autoimmunity 2007;29(4):257-61.
2007: Melvin Cohn; N Av Mitchison; William Paul; Arthur M Silverstein; David W Talmage; Martin Weigert
Reflections on the clonal-selection theory.
Nature reviews. Immunology 2007;7(10):823-30.
2007: William Paul
Dendritic cells bask in the limelight.
Cell 2007;130(6):967-70.
2007: Booki Min; Angela Thornton; Stephan M Caucheteux; Souheil-Antoine Younes; Keunhee Oh; Jane Hu-Li; William Paul
Gut flora antigens are not important in the maintenance of regulatory T cell heterogeneity and homeostasis.
European journal of immunology 2007;37(7):1916-23.
2007: S Prakash; William Paul; P W Robbins
Fibrosin, a novel fibrogenic cytokine, modulates expression of myofibroblasts.
Experimental and molecular pathology 2007;82(1):42-8.
2007: Joshua D Milner; Jerrold M Ward; Andrea Keane-Myers; William Paul
Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(2):576-81.
2006: Jinfang Zhu; Dragana Jankovic; Alex Grinberg; Liying Guo; William Paul
Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18214-9.
2006: Booki Min; Graham Le Gros; William Paul
Basophils: a potential liaison between innate and adaptive immunity.
Allergology international : official journal of the Japanese Society of Allergology 2006;55(2):99-104.
2006: Zvi Grossman; Martin Meier-Schellersheim; William Paul; Louis J Picker
Pathogenesis of HIV infection: what the virus spares is as important as what it destroys.
Nature medicine 2006;12(3):289-95.
2006: Jinfang Zhu; Hidehiro Yamane; Javier Cote-Sierra; Liying Guo; William Paul
GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors.
Cell research 2006;16(1):3-10.
2005: Liying Guo; Jane Hu-Li; William Paul
Probabilistic regulation of IL-4 production.
Journal of clinical immunology 2005;25(6):573-81.
2005: Kunihiro Yamaoka; Booki Min; Yong-Jie Zhou; William Paul; John O'Shea
Jak3 negatively regulates dendritic-cell cytokine production and survival.
Blood 2005;106(9):3227-33.
2005: Hidehiro Yamane; Jinfang Zhu; William Paul
Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment.
The Journal of experimental medicine 2005;202(6):793-804.
2005: Lars Tykocinski; Petra Hajkova; Hyun-Dong Chang; Torsten Stamm; Osman Sözeri; Max Löhning; Jane Hu-Li; Uwe Niesner; Stephan Kreher; Beate Friedrich; Christophe Pannetier; Gerald Grütz; Jörn Walter; William Paul; Andreas Radbruch
A critical control element for interleukin-4 memory expression in T helper lymphocytes.
The Journal of biological chemistry 2005;280(31):28177-85.
2005: Liying Guo; Jane Hu-Li; William Paul
Probabilistic regulation in TH2 cells accounts for monoallelic expression of IL-4 and IL-13.
Immunity 2005;23(1):89-99.
2005: Booki Min; William Paul
Endogenous proliferation: burst-like CD4 T cell proliferation in lymphopenic settings.
Seminars in immunology 2005;17(3):201-7.
2005: Booki Min; Hidehiro Yamane; Jane Hu-Li; William Paul
Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(10):6039-44.
2005: Irina Rochman; William Paul; Shlomo Z Ben-Sasson
IL-6 increases primed cell expansion and survival.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):4761-7.
2004: Jinfang Zhu; Booki Min; Jane Hu-Li; Cynthia J Watson; Alex Grinberg; Qi Wang; Nigel Killeen; Joseph F Urban; Liying Guo; William Paul
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.
Nature immunology 2004;5(11):1157-65.
2004: Booki Min; Melanie Prout; Jane Hu-Li; Jinfang Zhu; Dragana Jankovic; Ellen S Morgan; Joseph F Urban; Ann M Dvorak; Fred D Finkelman; Graham Le Gros; William Paul
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite.
The Journal of experimental medicine 2004;200(4):507-17.
2004: Petr Bocek; Gilles Foucras; William Paul
Interferon gamma enhances both in vitro and in vivo priming of CD4+ T cells for IL-4 production.
The Journal of experimental medicine 2004;199(12):1619-30.
2004: Zvi Grossman; Booki Min; Martin Meier-Schellersheim; William Paul
Concomitant regulation of T-cell activation and homeostasis.
Nature reviews. Immunology 2004;4(5):387-95.
2004: Javier Cote-Sierra; Gilles Foucras; Liying Guo; Lynda Chiodetti; Howard A Young; Jane Hu-Li; Jinfang Zhu; William Paul
Interleukin 2 plays a central role in Th2 differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(11):3880-5.
2004: Booki Min; Gilles Foucras; Martin Meier-Schellersheim; William Paul
Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(11):3874-9.
2004: Liying Guo; Jane Hu-Li; William Paul
Probabilistic regulation of IL-4 production in Th2 cells: accessibility at the Il4 locus.
Immunity 2004;20(2):193-203.
2003: Masaki Terabe; So Matsui; Jong Myun Park; Mizuko Mamura; Nancy Noben-Trauth; Debra D Donaldson; Wanjun Chen; Sharon M Wahl; Steve Ledbetter; Bruce Pratt; John J Letterio; William Paul; Jay A Berzofsky
Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence.
The Journal of experimental medicine 2003;198(11):1741-52.
2003: Jinfang Zhu; Javier Cote-Sierra; Liying Guo; William Paul
Stat5 activation plays a critical role in Th2 differentiation.
Immunity 2003;19(5):739-48.
2003: Max Löhning; Anne Richter; Torsten Stamm; Jane Hu-Li; Mario Assenmacher; William Paul; Andreas Radbruch
Establishment of memory for IL-10 expression in developing T helper 2 cells requires repetitive IL-4 costimulation and does not impair proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(21):12307-12.
2003: Hey Jin Chong; L Andrew Bouton; Daniel P Bailey; Harry Wright; Carlos D Ramirez; Anita Gharse; Carole A Oskeritzian; Han-Zhang Xia; Jinfang Zhu; William Paul; Christopher L Kepley; Lawrence B Schwartz; John J Ryan
IL-4 selectively enhances FcgammaRIII expression and signaling on mouse mast cells.
Cellular immunology 2003;224(2):65-73.
2003: Jean-Louis Boulay; John O'Shea; William Paul
Molecular phylogeny within type I cytokines and their cognate receptors.
Immunity 2003;19(2):159-63.
2003: Tracy L McGaha; Maithao N Le; Takao Kodera; Cristina Stoica; Jinfang Zhu; William Paul; Constantin A Bona
Molecular mechanisms of interleukin-4-induced up-regulation of type I collagen gene expression in murine fibroblasts.
Arthritis and rheumatism 2003;48(8):2275-84.
2003: William Paul; Ronald N Germain
Obituary: Charles A. Janeway Jr (1943-2003).
Nature 2003;423(6937):237.
2003: Nancy Noben-Trauth; Rosalia Lira; Hisashi Nagase; William Paul; David L Sacks
The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):5152-8.
2003: Tomohiro Yoshimoto; Booki Min; Takaaki Sugimoto; Nobuki Hayashi; Yuriko Ishikawa; Yuki Sasaki; Hitomi Hata; Kazuyoshi Takeda; Ko Okumura; Luc Van Kaer; William Paul; Kenji Nakanishi
Nonredundant roles for CD1d-restricted natural killer T cells and conventional CD4+ T cells in the induction of immunoglobulin E antibodies in response to interleukin 18 treatment of mice.
The Journal of experimental medicine 2003;197(8):997-1005.
2003: Booki Min; Rebecca S McHugh; Gregory D Sempowski; CRYSTAL MACKALL; Gilles Foucras; William Paul
Neonates support lymphopenia-induced proliferation.
Immunity 2003;18(1):131-40.
2002: Liying Guo; Jane Hu-Li; Jinfang Zhu; Cynthia J Watson; Michael J Difilippantonio; Christophe Pannetier; William Paul
In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10623-8.
2002: John O'Shea; William Paul
Regulation of T(H)1 differentiation--controlling the controllers.
Nature immunology 2002;3(6):506-8.
2002: Jinfang Zhu; Liying Guo; Booki Min; Cynthia J Watson; Jane Hu-Li; Howard A Young; Philip Tsichlis; William Paul
Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation.
Immunity 2002;16(5):733-44.
2002: Nancy Noben-Trauth; Jane Hu-Li; William Paul
IL-4 secreted from individual naive CD4+ T cells acts in an autocrine manner to induce Th2 differentiation.
European journal of immunology 2002;32(5):1428-33.
2002: Nobuki Hayashi; Dacai Liu; Booki Min; Shlomo Z Ben-Sasson; William Paul
Antigen challenge leads to in vivo activation and elimination of highly polarized TH1 memory T cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):6187-91.
2002: Zvi Grossman; Martin Meier-Schellersheim; Ana Sousa; Rui M M Victorino; William Paul
CD4+ T-cell depletion in HIV infection: are we closer to understanding the cause?
Nature medicine 2002;8(4):319-23.
2002: Takao Kodera; Tracy L McGaha; Robert Phelps; William Paul; Constantin A Bona
Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3800-5.
2002: Shlomo Z Ben-Sasson; Irena Zukovsky; Aliza Biton; Ron Vogel; Gilles Foucras; Nobuki Hayashi; William Paul
Generation and characterization of memory CD4 T cells.
Advances in experimental medicine and biology 2002;512():129-34.
2002: Booki Min; Gregory D Sempowski; William Paul
Neonates support "homeostatic" proliferation.
Advances in experimental medicine and biology 2002;512():91-5.
2001: A A Lighvani; David M Frucht; Dragana Jankovic; H Yamane; Julio Aliberti; Bruce D Hissong; B V Nguyen; Massimo Gadina; A Sher; William Paul; John O'Shea
T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15137-42.
2001: Zvi Grossman; William Paul
Autoreactivity, dynamic tuning and selectivity.
Current opinion in immunology 2001;13(6):687-98.
2001: Yongkang zhang; R Apilado; John Coleman; Shlomo Z Ben-Sasson; S Tsang; J Hu-Li; William Paul; Hua Huang
Interferon gamma stabilizes the T helper cell type 1 phenotype.
The Journal of experimental medicine 2001;194(2):165-72.
2001: Jinfang Zhu; Liying Guo; Cynthia J Watson; Jane Hu-Li; William Paul
Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansion.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7276-81.
2001: Liying Guo; Jane Hu-Li; Jinfang Zhu; Christophe Pannetier; C Watson; GJ McKenzie; Andrew N J McKenzie; William Paul
Disrupting Il13 impairs production of IL-4 specified by the linked allele.
Nature immunology 2001;2(5):461-6.
2001: Tracy L McGaha; S Saito; Robert G Phelps; R Gordon; Nancy Noben-Trauth; William Paul; Constantin A Bona
Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes.
The Journal of investigative dermatology 2001;116(1):136-43.
2001: Jane Hu-Li; Christophe Pannetier; Liying Guo; Max Löhning; Hua Gu; C Watson; Mario Assenmacher; Andreas Radbruch; William Paul
Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene.
Immunity 2001;14(1):1-11.
2001: Shlomo Z Ben-Sasson; R Gerstel; Jane Hu-Li; William Paul
Cell division is not a "clock" measuring acquisition of competence to produce IFN-gamma or IL-4.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):112-20.
2000: Masaki Terabe; S Matsui; Nancy Noben-Trauth; H Chen; C Watson; Debra D Donaldson; David P Carbone; William Paul; Jay A Berzofsky
NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway.
Nature immunology 2000;1(6):515-20.
2000: Dorel Radu; Nancy Noben-Trauth; Jane Hu-Li; William Paul; Constantin A Bona
A targeted mutation in the IL-4Ralpha gene protects mice against autoimmune diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12700-4.
2000: Jinfang Zhu; Hua Huang; L Guo; T Stonehouse; C J Watson; Jane Hu-Li; William Paul
Transient inhibition of interleukin 4 signaling by T cell receptor ligation.
The Journal of experimental medicine 2000;192(8):1125-34.
2000: Nancy Noben-Trauth; Jane Hu-Li; William Paul
Conventional, naive CD4+ T cells provide an initial source of IL-4 during Th2 differentiation.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(7):3620-5.
2000: William Paul; Rose G Mage
Elvin A. Kabat (1914-2000).
Nature 2000;407(6802):316.
2000: Zvi Grossman; William Paul
The impact of HIV on naïve T-cell homeostasis.
Nature medicine 2000;6(9):976-7.
2000: Tomohiro Yoshimoto; H Mizutani; Hiroko Tsutsui; Nancy Noben-Trauth; K Yamanaka; M Tanaka; S Izumi; H Okamura; William Paul; Kenji Nakanishi
IL-18 induction of IgE: dependence on CD4+ T cells, IL-4 and STAT6.
Nature immunology 2000;1(2):132-7.
2000: Zvi Grossman; William Paul
Self-tolerance: context dependent tuning of T cell antigen recognition.
Seminars in immunology 2000;12(3):197-203; discussion 257-344.
2000: Shlomo Z Ben-Sasson; Kirill Makedonski; Jane Hu-Li; William Paul
Survival and cytokine polarization of naive CD4(+) T cells in vitro is largely dependent on exogenous cytokines.
European journal of immunology 2000;30(5):1308-17.
2000: Dragana Jankovic; Marika C Kullberg; Nancy Noben-Trauth; Patricia Caspar; William Paul; Alan Sher
Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(6):3047-55.
2000: Hua Huang; William Paul
Protein tyrosine phosphatase activity is required for IL-4 induction of IL-4 receptor alpha-chain.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1211-5.
1999: Keats Nelms; TJ O'Neill; S Li; Stevan Hubbard; TA Gustafson; William Paul
Alternative splicing, gene localization, and binding of SH2-B to the insulin receptor kinase domain.
Mammalian genome : official journal of the International Mammalian Genome Society 1999;10(12):1160-7.
1999: T Yoshimoto; H Tsutsui; K Tominaga; K Hoshino; H Okamura; S Akira; William Paul; K Nakanishi
IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13962-6.
1999: Zvi Grossman; Michael A Polis; Mark B Feinberg; Z Grossman; Itai Levi; Shirley Jankelevich; Robert Yarchoan; J Boon; F de Wolf; J M Lange; J Goudsmit; Dimiter S Dimitrov; William Paul
Ongoing HIV dissemination during HAART.
Nature medicine 1999;5(10):1099-104.
1999: AL Dent; Timothy Doherty; William Paul; A Sher; Louis M Staudt
BCL-6-deficient mice reveal an IL-4-independent, STAT6-dependent pathway that controls susceptibility to infection by Leishmania major.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(4):2098-103.
1999: Dragana Jankovic; Marika C Kullberg; Nancy Noben-Trauth; Patricia Caspar; J M Ward; Allen W Cheever; William Paul; Alan Sher
Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):337-42.
1999: Nancy Noben-Trauth; William Paul; David L Sacks
IL-4- and IL-4 receptor-deficient BALB/c mice reveal differences in susceptibility to Leishmania major parasite substrains.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(10):6132-40.
1999: Christophe Pannetier; Jane Hu-Li; William Paul
Bias in the expression of IL-4 alleles: the use of T cells from a GFP knock-in mouse.
Cold Spring Harbor symposia on quantitative biology 1999;64():599-602.
1999: Keats Nelms; Achsah D Keegan; J Zamorano; John J Ryan; William Paul
The IL-4 receptor: signaling mechanisms and biologic functions.
Annual review of immunology 1999;17():701-38.
1998: AL Dent; Jane Hu-Li; William Paul; Louis M Staudt
T helper type 2 inflammatory disease in the absence of interleukin 4 and transcription factor STAT6.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13823-8.
1998: Zvi Grossman; Mark B Feinberg; V Kuznetsov; D Dimitrov; William Paul
HIV infection: how effective is drug combination treatment?
Immunology today 1998;19(11):528-32.
1998: H Chen; William Paul
A population of CD62Llow Nk1.1- CD4+ T cells that resembles NK1.1+ CD4+ T cells.
European journal of immunology 1998;28(10):3172-82.
1998: John J Ryan; LJ McReynolds; Hua Huang; Keats Nelms; William Paul
Characterization of a mobile Stat6 activation motif in the human IL-4 receptor.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1811-21.
1998: Keats Nelms; A L Snow; Jane Hu-Li; William Paul
FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation.
Immunity 1998;9(1):13-24.
1998: C C Chu; William Paul
Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis.
Molecular immunology 1998;35(8):487-502.
1998: H Huang; Christophe Pannetier; Jane Hu-Li; William Paul
Transient transfection of primary T helper cells by particle-mediated gene transfer.
Journal of immunological methods 1998;215(1-2):173-7.
1998: Zvi Grossman; Mark B Feinberg; William Paul
Multiple modes of cellular activation and virus transmission in HIV infection: a role for chronically and latently infected cells in sustaining viral replication.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6314-9.
1998: Hua Huang; William Paul
Impaired interleukin 4 signaling in T helper type 1 cells.
The Journal of experimental medicine 1998;187(8):1305-13.
1998: M Murakami; William Paul
Age-dependent appearance of NK1.1+ T cells in the livers of beta2-microglobulin knockout and SJL mice.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(6):2649-54.
1998: Keats Nelms; Hua Huang; J Ryan; Achsah D Keegan; William Paul
Interleukin-4 receptor signalling mechanisms and their biological significance.
Advances in experimental medicine and biology 1998;452():37-43.
1997: Hua Huang; Jane Hu-Li; H Chen; Shlomo Z Ben-Sasson; William Paul
IL-4 and IL-13 production in differentiated T helper type 2 cells is not IL-4 dependent.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(8):3731-8.
1997: Nancy Noben-Trauth; L D Shultz; F Brombacher; Joseph F Urban; Hua Gu; William Paul
An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(20):10838-43.
1997: H Chen; William Paul
Cultured NK1.1+ CD4+ T cells produce large amounts of IL-4 and IFN-gamma upon activation by anti-CD3 or CD1.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(5):2240-9.
1997: Dragana Jankovic; Marika C Kullberg; David Dombrowicz; S Barbieri; Patricia Caspar; Thomas A Wynn; William Paul; Allen W Cheever; Jean-Pierre Kinet; Alan Sher
Fc epsilonRI-deficient mice infected with Schistosoma mansoni mount normal Th2-type responses while displaying enhanced liver pathology.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):1868-75.
1997: H Chen; Hua Huang; William Paul
NK1.1+ CD4+ T cells lose NK1.1 expression upon in vitro activation.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(11):5112-9.
1997: John J Ryan; Hua Huang; LJ McReynolds; Christopher P Shelburne; Jane Hu-Li; Thomas Huff; William Paul
Stem cell factor activates STAT-5 DNA binding in IL-3-derived bone marrow mast cells.
Experimental hematology 1997;25(4):357-62.
1997: Jane Hu-Li; H Huang; J Ryan; William Paul
In differentiated CD4+ T cells, interleukin 4 production is cytokine-autonomous, whereas interferon gamma production is cytokine-dependent.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3189-94.
1997: C C Chu; William Paul
Fig1, an interleukin 4-induced mouse B cell gene isolated by cDNA representational difference analysis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2507-12.
1997: Helen Y Wang; Jose Zamorano; J L Yoerkie; William Paul; Achsah D Keegan
The IL-4-induced tyrosine phosphorylation of the insulin receptor substrate is dependent on JAK1 expression in human fibrosarcoma cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(3):1037-40.
1997: H Varmus; William Paul
AIDS: the process of discovery.
Science (New York, N.Y.) 1997;275(5297):141; author reply 142.
1997: William Paul
Interleukin 4: signalling mechanisms and control of T cell differentiation.
Ciba Foundation symposium 1997;204():208-16; discussion 216-9.
1996: S A Oakes; Fabio Candotti; JA Johnston; Y Q Chen; John J Ryan; N Taylor; Xibao Liu; Lothar Hennighausen; Luigi D Notarangelo; William Paul; R. Michael Blaese; John O'Shea
Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.
Immunity 1996;5(6):605-15.
1996: William Paul
Nutrition in pediatric HIV infection: setting the research agenda. Keynote address.
The Journal of nutrition 1996;126(10 Suppl):2599S-2601S.
1996: H Chen; C A Kinzer; William Paul
p161, a murine membrane protein expressed on mast cells and some macrophages, is mouse CD13/aminopeptidase N.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(6):2593-600.
1996: Harold Varmus; William Paul
Planning of US AIDS research.
Nature 1996;381(6580):270.
1996: N Nelson; Y Kanno; C Hong; C Contursi; T Fujita; B J Fowlkes; E O'Connell; J Hu-Li; William Paul; D Jankovic; A F Sher; J E Coligan; A Thornton; E Appella; Y Yang; Keiko Ozato
Expression of IFN regulatory factor family proteins in lymphocytes. Induction of Stat-1 and IFN consensus sequence binding protein expression by T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(10):3711-20.
1996: K Shimoda; Jan M A van Deursen; Mark Y Sangster; S R Sarawar; RT Carson; Ralph A Tripp; C Chu; F W Quelle; T Nosaka; Dario A A Vignali; Peter C Doherty; Gerard C Grosveld; William Paul; James N Ihle
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene.
Nature 1996;380(6575):630-3.
1996: John J Ryan; L J McReynolds; Achsah D Keegan; L H Wang; Evan Garfein; Paul B Rothman; Keats Nelms; William Paul
Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor.
Immunity 1996;4(2):123-32.
1996: Helen Y Wang; William Paul; Achsah D Keegan
IL-4 function can be transferred to the IL-2 receptor by tyrosine containing sequences found in the IL-4 receptor alpha chain.
Immunity 1996;4(2):113-21.
1995: T Yoshimoto; Albert Bendelac; C Watson; Jane Hu-Li; William Paul
Role of NK1.1+ T cells in a TH2 response and in immunoglobulin E production.
Science (New York, N.Y.) 1995;270(5243):1845-7.
1995: T Yoshimoto; Albert Bendelac; Jane Hu-Li; William Paul
Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11931-4.
1995: Alessandra B Pernis; B Witthuhn; Achsah D Keegan; Keats Nelms; Evan Garfein; J N Ihle; William Paul; JH Pierce; Paul B Rothman
Interleukin 4 signals through two related pathways.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7971-5.
1995: Achsah D Keegan; JA Johnston; P J Tortolani; L J McReynolds; C Kinzer; John O'Shea; William Paul
Similarities and differences in signal transduction by interleukin 4 and interleukin 13: analysis of Janus kinase activation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7681-5.
1995: C A Kinzer; Achsah D Keegan; William Paul
Identification of Fc epsilon RIneg mast cells in mouse bone marrow cell cultures. Use of a monoclonal anti-p161 antibody.
The Journal of experimental medicine 1995;182(2):575-9.
1995: John J Ryan; C A Kinzer; William Paul
Mast cells lacking the high affinity immunoglobulin E receptor are deficient in Fc epsilon RI gamma messenger RNA.
The Journal of experimental medicine 1995;182(2):567-74.
1995: William Paul
Can the immune response control HIV infection?
Cell 1995;82(2):177-82.
1995: Ling Mei Wang; Achsah D Keegan; M Frankel; William Paul; JH Pierce
Signal transduction through the IL-4 and insulin receptor families.
Stem cells (Dayton, Ohio) 1995;13(4):360-8.
1995: I Aoki; C Kinzer; A Shirai; William Paul; D M Klinman
IgE receptor-positive non-B/non-T cells dominate the production of interleukin 4 and interleukin 6 in immunized mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2534-8.
1995: William Paul
AIDS research policy.
Science (New York, N.Y.) 1995;267(5203):1405-7.
1995: William Paul
Basic science and clinical trials: interview with William Paul, director of the Office of AIDS Research. Interview by John S James.
AIDS treatment news 1995;(no 217):1, 4-7.
1995: William Paul
Reexamining AIDS research priorities.
Science (New York, N.Y.) 1995;267(5198):633-6.
1995: Kenji Nakanishi; Tomohiro Yoshimoto; C C Chu; H Matsumoto; K Hase; N Nagai; Toshiyuki Tanaka; M Miyasaka; William Paul; S Shinka
IL-2 inhibits IL-4-dependent IgE and IgG1 production in vitro and in vivo.
International immunology 1995;7(2):259-68.
1994: R A Goldstein; William Paul; D D Metcalfe; W W Busse; E R Reece
NIH conference. Asthma.
Annals of internal medicine 1994;121(9):698-708.
1994: Achsah D Keegan; Keats Nelms; Ling Mei Wang; JH Pierce; William Paul
Interleukin 4 receptor: signaling mechanisms.
Immunology today 1994;15(9):423-32.
1994: T Yoshimoto; William Paul
CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.
The Journal of experimental medicine 1994;179(4):1285-95.
1994: Achsah D Keegan; Keats Nelms; M White; Ling Mei Wang; JH Pierce; William Paul
An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth.
Cell 1994;76(5):811-20.
1994: William Paul; Robert A Seder
Lymphocyte responses and cytokines.
Cell 1994;76(2):241-51.
1994: Robert A Seder; Ronald N Germain; P S Linsley; William Paul
CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production.
The Journal of experimental medicine 1994;179(1):299-304.
1994: Robert A Seder; William Paul
Acquisition of lymphokine-producing phenotype by CD4+ T cells.
Annual review of immunology 1994;12():635-73.
1994: Achsah D Keegan; Keats Nelms; William Paul
The IL-4 receptor--signaling mechanisms.
Advances in experimental medicine and biology 1994;365():211-5.
1994: Ann M Dvorak; Robert A Seder; William Paul; Ellen S Morgan; Stephen J Galli
Effects of interleukin-3 with or without the c-kit ligand, stem cell factor, on the survival and cytoplasmic granule formation of mouse basophils and mast cells in vitro.
The American journal of pathology 1994;144(1):160-70.
1993: S M Russell; Achsah D Keegan; N Harada; Y Nakamura; M Noguchi; P Leland; M C Friedmann; A Miyajima; R K Puri; William Paul
Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor.
Science (New York, N.Y.) 1993;262(5141):1880-3.
1993: R Mandler; C C Chu; William Paul; Edward E Max; Clifford M Snapper
Interleukin 5 induces S mu-S gamma 1 DNA rearrangement in B cells activated with dextran-anti-IgD antibodies and interleukin 4: a three component model for Ig class switching.
The Journal of experimental medicine 1993;178(5):1577-86.
1993: Robert A Seder; R Gazzinelli; Alan Sher; William Paul
Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):10188-92.
1993: K W Bruhn; Keats Nelms; J L Boulay; William Paul; Michael J Lenardo
Molecular dissection of the mouse interleukin-4 promoter.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9707-11.
1993: C C Chu; E E Max; William Paul
DNA rearrangement can account for in vitro switching to IgG1.
The Journal of experimental medicine 1993;178(4):1381-90.
1993: Achsah D Keegan; L M Wang; William Paul; J H Pierce
Characterization of the interleukin 4 receptor. Structure and signal transduction pathways.
Research in immunology 1993;144(8):590-6.
1993: J L Boulay; William Paul
Hematopoietin sub-family classification based on size, gene organization and sequence homology.
Current biology : CB 1993;3(9):573-81.
1993: William Paul
Infectious diseases and the immune system.
Scientific American 1993;269(3):90-7.
1993: I Vorechovsky; J N Zhou; Lennart Hammarström; C I Edvard Smith; J D Thomas; William Paul; L D Notarangelo; E Bernatowska-Matuszkiewicz
Absence of xid mutation in X-linked agammaglobulinaemia.
Lancet 1993;342(8870):552.
1993: J D Thomas; Paschalis Sideras; C I Smith; Igor Vorechovský; Verne M Chapman; William Paul
Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes.
Science (New York, N.Y.) 1993;261(5119):355-8.
1993: T Tanaka; Jane Hu-Li; Robert A Seder; B Fazekas de St Groth; William Paul
Interleukin 4 suppresses interleukin 2 and interferon gamma production by naive T cells stimulated by accessory cell-dependent receptor engagement.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(13):5914-8.
1993: Ann M Dvorak; Robert A Seder; William Paul; S Kissell-Rainville; M Plaut; Stephen J Galli
Ultrastructural characteristics of Fc epsilon R-positive basophils in the spleen and bone marrow of mice immunized with goat anti-mouse IgD antibody.
Laboratory investigation; a journal of technical methods and pathology 1993;68(6):708-15.
1993: A Gross; S Z Ben-Sasson; William Paul
Anti-IL-4 diminishes in vivo priming for antigen-specific IL-4 production by T cells.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(6):2112-20.
1993: William Paul; Robert A Seder; M Plaut
Lymphokine and cytokine production by Fc epsilon RI+ cells.
Advances in immunology 1993;53():1-29.
1992: Ling Mei Wang; Achsah D Keegan; William Paul; MA Heidaran; J Silvio Gutkind; JH Pierce
IL-4 activates a distinct signal transduction cascade from IL-3 in factor-dependent myeloid cells.
The EMBO journal 1992;11(13):4899-908.
1992: Zvi Grossman; William Paul
Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10365-9.
1992: U Atasoy; C Watson; William Paul
Derivation of a monoclonal anti-murine IL-4 antibody specific for an epitope expressed on denatured molecules.
Cytokine 1992;4(6):537-44.
1992: J L Boulay; William Paul
The interleukin-4-related lymphokines and their binding to hematopoietin receptors.
The Journal of biological chemistry 1992;267(29):20525-8.
1992: Robert A Seder; William Paul; M M Davis; B Fazekas de St Groth
The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice.
The Journal of experimental medicine 1992;176(4):1091-8.
1992: W K Tsang; J Mizuguchi; Y Ishida; C Watson; T Chused; J Inman; David Margulies; William Paul
Failure of signaling through a chimeric class I-immunoglobulin molecule expressed on the surface of transfected B lymphoma cells and cells of transgenic mice.
Cellular immunology 1992;143(1):80-96.
1992: C C Chu; William Paul; E E Max
Quantitation of immunoglobulin mu-gamma 1 heavy chain switch region recombination by a digestion-circularization polymerase chain reaction method.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):6978-82.
1992: Z S Ye; J P Kinet; William Paul
Structure of the gene for the alpha-chain of the mouse high affinity receptor for IgE (Fc epsilon RI).
Journal of immunology (Baltimore, Md. : 1950) 1992;149(3):897-900.
1992: J L Boulay; William Paul
The interleukin-4 family of lymphokines.
Current opinion in immunology 1992;4(3):294-8.
1992: William Paul
Cytokines. Poking holes in the network.
Nature 1992;357(6373):16-7.
1992: William Paul; T Kishimoto; F Melchers; D Metcalf; T Mosmann; J Oppenheim; N Ruddle; J Van Snick
Nomenclature for secreted regulatory proteins of the immune system (interleukins). WHO-IUIS Nomenclature Subcommittee on Interleukin Designation.
Clinical and experimental immunology 1992;88(2):367.
1992: Robert A Seder; J L Boulay; F Finkelman; S Barbier; S Z Ben-Sasson; Graham Le Gros; William Paul
CD8+ T cells can be primed in vitro to produce IL-4.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(6):1652-6.
1992: Albert Bendelac; Polly Matzinger; R A Seder; William Paul; Ronald H Schwartz
Activation events during thymic selection.
The Journal of experimental medicine 1992;175(3):731-42.
1992: T Tanaka; C C Chu; William Paul
An antisense oligonucleotide complementary to a sequence in I gamma 2b increases gamma 2b germline transcripts, stimulates B cell DNA synthesis, and inhibits immunoglobulin secretion.
The Journal of experimental medicine 1992;175(2):597-607.
1992: Achsah D Keegan; William Paul
Multichain immune recognition receptors: similarities in structure and signaling pathways.
Immunology today 1992;13(2):63-8.
1991: William Paul
IL-6: a multifunctional regulator of immunity and inflammation.
Japanese journal of cancer research : Gann 1991;82(12):1458-9.
1991: Achsah D Keegan; J H Pierce; J Artrip; M Plaut; William Paul
Ligand stimulation of transfected and endogenous growth factor receptors enhances cytokine production by mast cells.
The EMBO journal 1991;10(12):3675-82.
1991: Robert A Seder; M Plaut; S Barbieri; J Urban; F D Finkelman; William Paul
Purified Fc epsilon R+ bone marrow and splenic non-B, non-T cells are highly enriched in the capacity to produce IL-4 in response to immobilized IgE, IgG2a, or ionomycin.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(3):903-9.
1991: Joseph F Urban; I M Katona; William Paul; Fred D Finkelman
Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(13):5513-7.
1991: I M Katona; Joseph F Urban; S S Kang; William Paul; Fred D Finkelman
IL-4 requirements for the generation of secondary in vivo IgE responses.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(12):4215-21.
1991: T Tanaka; S Z Ben-Sasson; William Paul
IL-4 increases IL-2 production by T cells in response to accessory cell-independent stimuli.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(11):3831-9.
1991: William Paul
Interleukin-4: a prototypic immunoregulatory lymphokine.
Blood 1991;77(9):1859-70.
1991: Dennis Y Kunimoto; K C Allison; C Watson; T Fuerst; Glen D Armstrong; William Paul; W Strober
High-level production of murine interleukin-5 (IL-5) utilizing recombinant baculovirus expression. Purification of the rIL-5 and its use in assessing the biologic role of IL-5 glycosylation.
Cytokine 1991;3(3):224-30.
1991: Robert A Seder; Graham Le Gros; S Z Ben-Sasson; J Urban; F D Finkelman; William Paul
Increased frequency of interleukin 4-producing T cells as a result of polyclonal priming. Use of a single-cell assay to detect interleukin 4-producing cells.
European journal of immunology 1991;21(5):1241-7.
1991: Achsah D Keegan; M P Beckmann; L S Park; William Paul
The IL-4 receptor: biochemical characterization of IL-4-binding molecules in a T cell line expressing large numbers of receptors.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(7):2272-9.
1991: Robert A Seder; William Paul; Ann M Dvorak; Saul J Sharkis; A Kagey-Sobotka; Y Niv; F D Finkelman; S A Barbieri; Stephen J Galli; M Plaut
Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2835-9.
1991: William Paul
Interleukin-4 production by Fc epsilon R+ cells.
Skin pharmacology : the official journal of the Skin Pharmacology Society 1991;4 Suppl 1():8-14.
1991: Robert A Seder; William Paul; S Z Ben-Sasson; Graham Le Gros; A Kagey-Sobotka; F D Finkelman; J H Pierce; M Plaut
Production of interleukin-4 and other cytokines following stimulation of mast cell lines and in vivo mast cells/basophils.
International archives of allergy and applied immunology 1991;94(1-4):137-40.
1990: Graham Le Gros; S Z Ben-Sasson; Daniel H Conrad; I Clark-Lewis; F D Finkelman; M Plaut; William Paul
IL-3 promotes production of IL-4 by splenic non-B, non-T cells in response to Fc receptor cross-linkage.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(8):2500-6.
1990: Graham Le Gros; S Z Ben-Sasson; Robert A Seder; F D Finkelman; William Paul
Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells.
The Journal of experimental medicine 1990;172(3):921-9.
1990: S Z Ben-Sasson; Graham Le Gros; Daniel H Conrad; F D Finkelman; William Paul
IL-4 production by T cells from naive donors. IL-2 is required for IL-4 production.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(4):1127-36.
1990: William Paul
B-cell activation and the one B cell/one antibody paradigm.
Immunological reviews 1990;115():197-204; discussion 205-9.
1990: Daniel H Conrad; S Z Ben-Sasson; Graham Le Gros; F D Finkelman; William Paul
Infection with Nippostrongylus brasiliensis or injection of anti-IgD antibodies markedly enhances Fc-receptor-mediated interleukin 4 production by non-B, non-T cells.
The Journal of experimental medicine 1990;171(5):1497-508.
1990: S Z Ben-Sasson; Graham Le Gros; Daniel H Conrad; F D Finkelman; William Paul
Cross-linking Fc receptors stimulate splenic non-B, non-T cells to secrete interleukin 4 and other lymphokines.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1421-5.
1990: Fred D Finkelman; J Holmes; I M Katona; Joseph F Urban; M P Beckmann; L S Park; Kenneth Schooley; R L Coffman; T R Mosmann; William Paul
Lymphokine control of in vivo immunoglobulin isotype selection.
Annual review of immunology 1990;8():303-33.
1989: Clifford M Snapper; J J Hooley; U Atasoy; Fred D Finkelman; William Paul
Differential regulation of murine B cell Fc gamma RII expression by CD4+ T helper subsets.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(7):2133-41.
1989: Peter Hornbeck; H Nakabayashi; B J Fowlkes; William Paul; D Kligman
A major myristylated substrate of protein kinase C and protein kinase C itself are differentially regulated during murine B- and T-lymphocyte development and activation.
Molecular and cellular biology 1989;9(9):3727-35.
1989: Achsah D Keegan; C M Snapper; R Van Dusen; William Paul; D H Conrad
Superinduction of the murine B cell Fc epsilon RII by T helper cell clones. Role of IL-4.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(11):3868-74.
1989: William Paul
Pleiotropy and redundancy: T cell-derived lymphokines in the immune response.
Cell 1989;57(4):521-4.
1989: M Plaut; J H Pierce; C J Watson; J Hanley-Hyde; R P Nordan; William Paul
Mast cell lines produce lymphokines in response to cross-linkage of Fc epsilon RI or to calcium ionophores.
Nature 1989;339(6219):64-7.
1989: D L Jankovic; Maryse Gibert; D Baran; J Ohara; William Paul; J Theze
Activation by IL-2, but not IL-4, up-regulates the expression of the p55 subunit of the IL-2 receptor on IL-2- and IL-4-dependent T cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(9):3113-20.
1989: C Peschel; I Green; William Paul
Interleukin-4 induces a substance in bone marrow stromal cells that reversibly inhibits factor-dependent and factor-independent cell proliferation.
Blood 1989;73(5):1130-41.
1989: C Peschel; I Green; William Paul
Preferential proliferation of immature B lineage cells in long-term stromal cell-dependent cultures with IL-4.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(5):1558-68.
1989: Jane Hu-Li; J Ohara; C Watson; W Tsang; William Paul
Derivation of a T cell line that is highly responsive to IL-4 and IL-2 (CT.4R) and of an IL-2 hyporesponsive mutant of that line (CT.4S).
Journal of immunology (Baltimore, Md. : 1950) 1989;142(3):800-7.
1989: C Hauser; C M Snapper; J Ohara; William Paul; Stephen I Katz
T helper cells grown with hapten-modified cultured Langerhans' cells produce interleukin 4 and stimulate IgE production by B cells.
European journal of immunology 1989;19(2):245-51.
1989: Fred D Finkelman; J Holmes; Joseph F Urban; William Paul; I M Katona
T help requirements for the generation of an in vivo IgE response: a late acting form of T cell help other than IL-4 is required for IgE but not for IgG1 production.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(2):403-8.
1989: William Paul
Nomenclatre Committee, Working Group on Lymphokines.
Immunology 1989;66(1):156-7.
1989: Fred D Finkelman; I M Katona; J F Urban; William Paul
Control of in vivo IgE production in the mouse by interleukin 4.
Ciba Foundation symposium 1989;147():3-17; discussion 17-22.
1988: William Paul
Lymphokine nomenclature.
Immunology today 1988;9(12):366-7.
1988: William Paul
International Union of Immunological Societies. Nomenclature Committee Working Group on Lymphokines.
Cellular immunology 1988;117(2):430-2.
1988: William Paul
International Union of Immunological Societies. Nomenclature committee working group on lymphokines.
Clinical immunology and immunopathology 1988;49(3):498-500.
1988: William Paul
International Union of Immunological Societies. Nomenclature Committee Working Group on Lymphokines.
Journal of immunological methods 1988;115(1):1-2.
1988: J Ohara; William Paul
Up-regulation of interleukin 4/B-cell stimulatory factor 1 receptor expression.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(21):8221-5.
1988: Peter D'Eustachio; M Brown; C Watson; William Paul
The IL-4 gene maps to chromosome 11, near the gene encoding IL-3.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(9):3067-71.
1988: Fred D Finkelman; I M Katona; Joseph F Urban; J Holmes; J Ohara; A S Tung; J V Sample; William Paul
IL-4 is required to generate and sustain in vivo IgE responses.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(7):2335-41.
1988: Clifford M Snapper; Peter Hornbeck; U Atasoy; Geraldo Pereira; William Paul
Interleukin 4 induces membrane Thy-1 expression on normal murine B cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):6107-11.
1988: Clifford M Snapper; F D Finkelman; D Stefany; Daniel H Conrad; William Paul
IL-4 induces co-expression of intrinsic membrane IgG1 and IgE by murine B cells stimulated with lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(2):489-98.
1988: M Brown; Jane Hu-Li; William Paul
IL-4/B cell stimulatory factor 1 stimulates T cell growth by an IL-2-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(2):504-11.
1988: Peter Hornbeck; K P Huang; William Paul
Lamin B is rapidly phosphorylated in lymphocytes after activation of protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(7):2279-83.
1988: Clifford M Snapper; C Peschel; William Paul
IFN-gamma stimulates IgG2a secretion by murine B cells stimulated with bacterial lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(7):2121-7.
1988: M V Sitkovsky; William Paul
Immunology. Global or directed exocytosis?
Nature 1988;332(6162):306-7.
1988: G Trenn; H Takayama; Jane Hu-Li; William Paul; Michail V Sitkovsky
B cell stimulatory factor 1 (IL-4) enhances the development of cytotoxic T cells from Lyt-2+ resting murine T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(4):1101-6.
1988: L Tentori; Drew M Pardoll; J C Zuñiga; J Hu-Li; William Paul; J A Bluestone; A M Kruisbeek
Proliferation and production of IL-2 and B cell stimulatory factor 1/IL-4 in early fetal thymocytes by activation through Thy-1 and CD3.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(4):1089-94.
1988: C M Snapper; F D Finkelman; William Paul
Regulation of IgG1 and IgE production by interleukin 4.
Immunological reviews 1988;102():51-75.
1988: Clifford M Snapper; F D Finkelman; William Paul
Differential regulation of IgG1 and IgE synthesis by interleukin 4.
The Journal of experimental medicine 1988;167(1):183-96.
1988: B S Polla; J Ohara; William Paul; N Nabavi; A Myer; H C Liou; F W Shen; S Gillis; J V Bonventre; Laurie H Glimcher
Differential induction of class II gene expression in murine pre-B-cell lines by B-cell stimulatory factor-1 and by antibodies to B-cell surface antigens.
The Journal of molecular and cellular immunology : JMCI 1988;3(6):363-73.
1988: R M Crawford; D S Finbloom; J Ohara; William Paul; M S Meltzer
Regulation of macrophage effector function by B cell stimulatory factor-1 (BSF-1).
Advances in experimental medicine and biology 1988;239():223-9.
1987: J N Siegel; C A Turner; D M Klinman; M Wilkinson; A D Steinberg; C L MacLeod; William Paul; M M Davis; D I Cohen
Sequence analysis and expression of an X-linked, lymphocyte-regulated gene family (XLR).
The Journal of experimental medicine 1987;166(6):1702-15.
1987: William Paul
Interleukin 4/B cell stimulatory factor 1: one lymphokine, many functions.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1987;1(6):456-61.
1987: E A Kurt-Jones; S Hamberg; J Ohara; William Paul; Abul K Abbas
Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness.
The Journal of experimental medicine 1987;166(6):1774-87.
1987: C Peschel; I Green; J Ohara; William Paul
Role of B cell stimulatory factor 1/interleukin 4 in clonal proliferation of B cells.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(10):3338-47.
1987: M A Brown; J H Pierce; C J Watson; J Falco; J N Ihle; William Paul
B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells.
Cell 1987;50(5):809-18.
1987: J Ohara; J E Coligan; Kathy Zoon; W L Maloy; William Paul
High-efficiency purification and chemical characterization of B cell stimulatory factor-1/interleukin 4.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(4):1127-34.
1987: J Mizuguchi; Y Y Ji; H Nakabayaschi; K P Huang; M A Beaven; T Chused; William Paul
Protein kinase C activation blocks anti-IgM-mediated signaling BAL17 B lymphoma cells.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(4):1054-9.
1987: C Peschel; William Paul; J Ohara; I Green
Effects of B cell stimulatory factor-1/interleukin 4 on hematopoietic progenitor cells.
Blood 1987;70(1):254-63.
1987: C M Snapper; William Paul
B cell stimulatory factor-1 (interleukin 4) prepares resting murine B cells to secrete IgG1 upon subsequent stimulation with bacterial lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(1):10-7.
1987: William Paul
Between two centuries: specificity and regulation in immunology.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(1):1-6.
1987: R M Crawford; D S Finbloom; J Ohara; William Paul; M S Meltzer
B cell stimulatory factor-1 (interleukin 4) activates macrophages for increased tumoricidal activity and expression of Ia antigens.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(1):135-41.
1987: C M Snapper; William Paul
Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production.
Science (New York, N.Y.) 1987;236(4804):944-7.
1987: A H Lichtman; M E Williams; J Ohara; William Paul; D V Faller; A K Abbas
Retrovirus infection alters growth factor responses of T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(10):3276-83.
1987: K Nakanishi; T Hashimoto; K Hiroishi; K Matsui; T Yoshimoto; Herbert C Morse; J Furuyama; T Hamaoka; K Higashino; William Paul
Demonstration of up-regulated IL 2 receptor expression on an in vitro cloned BCL1 subline.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(6):1817-25.
1987: J Ohara; William Paul
Receptors for B-cell stimulatory factor-1 expressed on cells of haematopoietic lineage.
Nature 1987;325(6104):537-40.
1987: William Paul; J Mizuguchi; M A Beaven; Peter Hornbeck; W Tsang; J Ohara
B lymphocyte activation. The roles of receptor cross-linkage and BSF-1.
Advances in experimental medicine and biology 1987;213():207-14.
1987: William Paul; J Ohara
B-cell stimulatory factor-1/interleukin 4.
Annual review of immunology 1987;5():429-59.
1987: Jane Hu-Li; E M Shevach; J Mizuguchi; J Ohara; T Mosmann; William Paul
B cell stimulatory factor 1 (interleukin 4) is a potent costimulant for normal resting T lymphocytes.
The Journal of experimental medicine 1987;165(1):157-72.
1987: William Paul; M Brown; Peter Hornbeck; J Mizuguchi; J Ohara; E Rabin; Clifford M Snapper; W Tsang
Regulation of B-lymphocyte activation, proliferation, and differentiation.
Annals of the New York Academy of Sciences 1987;505():82-9.
1986: B S Polla; A Poljak; S Geier; Stanley G Nathenson; J Ohara; William Paul; L H Glimcher
Regulation of class II gene expression in a murine pre-B cell line.
Federation proceedings 1986;45(13):2995-9.
1986: F D Finkelman; I M Katona; J F Urban; Clifford M Snapper; J Ohara; William Paul
Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor 1.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(24):9675-8.
1986: B S Polla; A Poljak; J Ohara; William Paul; L H Glimcher
Regulation of class II gene expression: analysis in B cell stimulatory factor 1-inducible murine pre-B cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(10):3332-7.
1986: Peter Hornbeck; William Paul
Anti-immunoglobulin and phorbol ester induce phosphorylation of proteins associated with the plasma membrane and cytoskeleton in murine B lymphocytes.
The Journal of biological chemistry 1986;261(31):14817-24.
1986: F D Finkelman; J Ohara; D K Goroff; J Smith; N Villacreses; J J Mond; William Paul
Production of BSF-1 during an in vivo, T-dependent immune response.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(9):2878-85.
1986: J Mizuguchi; M A Beaven; J Ohara; William Paul
BSF-1 action on resting B cells does not require elevation of inositol phospholipid metabolism or increased [Ca2+]i.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(7):2215-9.
1986: J Mizuguchi; W Tsang; S L Morrison; M A Beaven; William Paul
Membrane IgM, IgD, and IgG act as signal transmission molecules in a series of B lymphomas.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(7):2162-7.
1986: E M Rabin; J J Mond; J Ohara; William Paul
Interferon-gamma inhibits the action of B cell stimulatory factor (BSF)-1 on resting B cells.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(5):1573-6.
1986: E M Rabin; J J Mond; J Ohara; William Paul
B cell stimulatory factor 1 (BSF-1) prepares resting B cells to enter S phase in response to anti-IgM and lipopolysaccharide.
The Journal of experimental medicine 1986;164(2):517-31.
1986: TR Mosmann; M W Bond; Robert L Coffman; J Ohara; William Paul
T-cell and mast cell lines respond to B-cell stimulatory factor 1.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(15):5654-8.
1986: S Ono; S Hayashi; Y Takahama; K Dobashi; Y Katoh; K Nakanishi; William Paul; T Hamaoka
Identification of two distinct factors, B151-TRF1 and B151-TRF2, inducing differentiation of activated B cells and small resting B cells into antibody-producing cells.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(1):187-96.
1986: B S Polla; A Poljak; S G Geier; Stanley G Nathenson; J Ohara; William Paul; L H Glimcher
Three distinct signals can induce class II gene expression in a murine pre-B-cell line.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(13):4878-82.
1986: Robert L Coffman; J Ohara; M W Bond; J Carty; Albert Zlotnik; William Paul
B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(12):4538-41.
1986: J Mizuguchi; M A Beaven; J H Li; William Paul
Phorbol myristate acetate inhibits anti-IgM-mediated signaling in resting B cells.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(12):4474-8.
1986: William Paul; J Mizuguchi; M Brown; K Nakanishi; Peter Hornbeck; E Rabin; J Ohara
Regulation of B-lymphocyte activation, proliferation, and immunoglobulin secretion.
Cellular immunology 1986;99(1):7-13.
1986: M A Brown; C Watson; J Ohara; William Paul
In vitro translation of B-cell stimulatory factor-1 in Xenopus laevis oocytes.
Cellular immunology 1986;98(2):538-43.
1986: R N Germain; N S Braunstein; M A Brown; L H Glimcher; R I Lechler; J McCluskey; David Margulies; J Miller; M A Norcross; William Paul
Structure and function of murine class II major histocompatibility complex genes.
The Mount Sinai journal of medicine, New York 1986;53(3):194-201.
1986: M A Brown; L A Glimcher; E A Nielsen; William Paul; R N Germain
T-cell recognition of Ia molecules selectively altered by a single amino acid substitution.
Science (New York, N.Y.) 1986;231(4735):255-8.
1986: E Simpson; R Lieberman; I Andó; D H Sachs; William Paul; J A Berzofsky
How many class II immune response genes? A reappraisal of the evidence.
Immunogenetics 1986;23(5):302-8.
1986: S Chatterjee-Das; G G Schlauder; D H Sachs; L H Glimcher; William Paul; David J McKean
A biochemical analysis of Ak molecules from mutant antigen presenting cell lines.
Immunogenetics 1986;23(2):121-5.
1985: E S Vitetta; J Ohara; C D Myers; J E Layton; P H Krammer; William Paul
Serological, biochemical, and functional identity of B cell-stimulatory factor 1 and B cell differentiation factor for IgG1.
The Journal of experimental medicine 1985;162(5):1726-31.
1985: J Ohara; S Lahet; J Inman; William Paul
Partial purification of murine B cell stimulatory factor (BSF)-1.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(4):2518-23.
1985: A L DeFranco; E S Raveche; William Paul
Separate control of B lymphocyte early activation and proliferation in response to anti-IgM antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(1):87-94.
1985: J Ohara; William Paul
Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1.
Nature 1985;315(6017):333-6.
1985: J D Ashwell; A L DeFranco; William Paul; R H Schwartz
Can resting B cells present antigen to T cells?
Federation proceedings 1985;44(8):2475-9.
1985: G G Schlauder; Michael P Bell; William Paul; L H Glimcher; David J McKean
Biochemical characterization of I-Ak proteins from mutant antigen-presenting B-cell--B-lymphoma hybridomas.
Molecular immunology 1985;22(5):597-607.
1985: E M Rabin; J Ohara; William Paul
B-cell stimulatory factor 1 activates resting B cells.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(9):2935-9.
1985: D I Cohen; A D Steinberg; William Paul; M M Davis
Expression of an X-linked gene family (XLR) in late-stage B cells and its alteration by the xid mutation.
Nature 1985;314(6009):372-4.
1985: D I Cohen; S M Hedrick; E A Nielsen; P D'Eustachio; F Ruddle; A D Steinberg; William Paul; M M Davis
Isolation of a cDNA clone corresponding to an X-linked gene family (XLR) closely linked to the murine immunodeficiency disorder xid.
Nature 1985;314(6009):369-72.
1985: William Paul
Living with lymphocytes.
International archives of allergy and applied immunology 1985;77(1-2):7-12.
1984: K Nakanishi; D I Cohen; M Blackman; E Nielsen; J Ohara; T Hamaoka; M E Koshland; William Paul
Ig RNA expression in normal B cells stimulated with anti-IgM antibody and T cell-derived growth and differentiation factors.
The Journal of experimental medicine 1984;160(6):1736-51.
1984: K Nakanishi; Thomas R Malek; Kendall A Smith; T Hamaoka; E M Shevach; William Paul
Both interleukin 2 and a second T cell-derived factor in EL-4 supernatant have activity as differentiation factors in IgM synthesis.
The Journal of experimental medicine 1984;160(6):1605-21.
1984: William Paul
Nomenclature of lymphokines which regulate B-lymphocytes.
Molecular immunology 1984;21(4):343.
1984: William Paul
Nomenclature for B-cell stimulatory factors.
Cellular immunology 1984;84(2):461-2.
1984: M Howard; K Nakanishi; William Paul
B cell growth and differentiation factors.
Immunological reviews 1984;78():185-210.
1984: M M Davis; D I Cohen; E A Nielsen; M Steinmetz; William Paul; L Hood
Cell-type-specific cDNA probes and the murine I region: the localization and orientation of Ad alpha.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(7):2194-8.
1984: Patricia Mongini; Dan Longo; William Paul
T cell regulation of immunoglobulin class expression in the B cell response to TNP-Ficoll: characterization of the T cell responsible for preferential enhancement of the IgG2a response.
Journal of immunology (Baltimore, Md. : 1950) 1984;132(4):1647-53.
1984: J D Ashwell; A L DeFranco; William Paul; R H Schwartz
Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation.
The Journal of experimental medicine 1984;159(3):881-905.
1984: A L DeFranco; J D Ashwell; R H Schwartz; William Paul
Polyclonal stimulation of resting B lymphocytes by antigen-specific T lymphocytes.
The Journal of experimental medicine 1984;159(3):861-80.
1984: William Paul
Nomenclature for lymphokines regulating B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1984;132(2):1056.
1984: William Paul
Lymphokine nomenclature.
Immunogenetics 1984;19(1):93-4.
1983: M Howard; L Matis; Thomas R Malek; E Shevach; W Kell; D Cohen; K Nakanishi; William Paul
Interleukin 2 induces antigen-reactive T cell lines to secrete BCGF-I.
The Journal of experimental medicine 1983;158(6):2024-39.
1983: J J Mond; G Norton; William Paul; I Scher; F D Finkelman; S House; M Schaefer; Patricia Mongini; C Hansen; C Bona
Establishment of an inbred line of mice that express a synergistic immune defect precluding in vitro responses to type 1 and type 2 antigens, B cell mitogens, and a number of T cell-derived helper factors.
The Journal of experimental medicine 1983;158(5):1401-14.
1983: L H Glimcher; S O Sharrow; William Paul
Serologic and functional characterization of a panel of antigen-presenting cell lines expressing mutant I-A class II molecules.
The Journal of experimental medicine 1983;158(5):1573-88.
1983: J J Farrar; M Howard; J Fuller-Farrar; William Paul
Biochemical and physicochemical characterization of mouse B cell growth factor: a lymphokine distinct from interleukin 2.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(4):1838-42.
1983: L A Matis; L H Glimcher; William Paul; R H Schwartz
Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(19):6019-23.
1983: J J Mond; J Farrar; William Paul; J Fuller-Farrar; M Schaefer; M Howard
T cell dependence and factor reconstitution of in vitro antibody responses to TNP-B. Abortus and TNP-Ficoll: restoration of depleted responses with chromatographed fractions of a T cell-derived factor.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(2):633-7.
1983: B Goldberg; William Paul; C A Bona
Idiotype-antiidiotype regulation. IV. Expression of common regulatory idiotopes on fructosan-binding and non-fructosan-binding monoclonal immunoglobulin.
The Journal of experimental medicine 1983;158(2):515-28.
1983: M Howard; S B Mizel; L Lachman; J Ansel; B Johnson; William Paul
Role of interleukin 1 in anti-immunoglobulin-induced B cell proliferation.
The Journal of experimental medicine 1983;157(5):1529-43.
1983: K Nakanishi; M Howard; A Muraguchi; J Farrar; K Takatsu; T Hamaoka; William Paul
Soluble factors involved in B cell differentiation: identification of two distinct T cell-replacing factors (TRF).
Journal of immunology (Baltimore, Md. : 1950) 1983;130(5):2219-24.
1983: L H Glimcher; T Hamano; R Asofsky; D H Sachs; M Pierres; L E Samelson; S O Sharrow; William Paul
IA mutant functional antigen-presenting cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1983;130(5):2287-94.
1983: K E Stein; D A Zopf; Carole B Miller; B M Johnson; Patricia Mongini; A Ahmed; William Paul
Immune response to a thymus-dependent form of B512 dextran requires the presence of Lyb-5+ lymphocytes.
The Journal of experimental medicine 1983;157(2):657-66.
1983: Patricia Mongini; William Paul; E S Metcalf
IgG subclass, IgE, and IgA anti-trinitrophenyl antibody production within trinitrophenyl-Ficoll-responsive B cell clones. Evidence in support of three distinct switching pathways.
The Journal of experimental medicine 1983;157(1):69-85.
1983: L H Glimcher; A M Kruisbeek; William Paul; I Green
Functional activity of a transformed thymic epithelial cell line.
Scandinavian journal of immunology 1983;17(1):1-11.
1983: M Howard; William Paul
Regulation of B-cell growth and differentiation by soluble factors.
Annual review of immunology 1983;1():307-33.
1982: T T Hecht; William Paul
Limitation of VSV infection by the host's response to VSV-associated cellular antigens.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(4):1736-41.
1982: L H Glimcher; T Hamano; R Asofsky; E Herber-Katz; S Hedrick; R H Schwartz; William Paul
I region-restricted antigen presentation by B cell-B lymphoma hybridomas.
Nature 1982;298(5871):283-4.
1982: J T Kung; S O Sharrow; M G Mage; William Paul
Detection of a common antigen on murine B cells and Lyt-2+ T cells by a rat monoclonal antibody, 14D10.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(1):81-6.
1982: Patricia Mongini; William Paul
T cell regulation of the IgG2a response to TNP-Ficoll: evidence that allotype congenic mice contain both helper cells that preferentially enhance IgG2a synthesis and suppressor cells that specifically suppress IgG2 synthesis.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(6):2405-10.
1982: A L Defranco; E S Raveche; R Asofsky; William Paul
Frequency of B lymphocytes responsive to anti-immunoglobulin.
The Journal of experimental medicine 1982;155(5):1523-36.
1982: J T Kung; S O Sharrow; A Ahmed; R Habbersett; I Scher; William Paul
B lymphocyte subpopulation defined by a rat monoclonal antibody, 14G8.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(5):2049-56.
1982: M Howard; J Farrar; M Hilfiker; B Johnson; K Takatsu; T Hamaoka; William Paul
Identification of a T cell-derived b cell growth factor distinct from interleukin 2.
The Journal of experimental medicine 1982;155(3):914-23.
1982: Patricia Mongini; William Paul; E S Metcalf
T cell regulation of immunoglobulin class expression in the antibody response to trinitrophenyl-ficoll. Evidence for T cell enhancement of the immunoglobulin class switch.
The Journal of experimental medicine 1982;155(3):884-902.
1982: J J Mond; I Scher; J Cossman; S Kessler; Patricia Mongini; C Hansen; F D Finkelman; William Paul
Role of the thymus in directing the development of a subset of B lymphocytes.
The Journal of experimental medicine 1982;155(3):924-36.
1982: K E Stein; D A Zopf; B M Johnson; Carole B Miller; William Paul
The immune response to an isomaltohexosyl-protein conjugate, a thymus-dependent analogue of alpha(1 replaced by 6) dextran.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(3):1350-4.
1982: L H Glimcher; K J Kim; I Green; William Paul
Ia antigen-bearing B cell tumor lines can present protein antigen and alloantigen in a major histocompatibility complex-restricted fashion to antigen-reactive T cells.
The Journal of experimental medicine 1982;155(2):445-59.
1982: M Howard; William Paul
Interleukins for B lymphocytes.
Lymphokine research 1982;1(1):1-4.
1982: William Paul; A DeFranco; B Sredni; M Howard
Long term growth of B-lymphocytes.
Annals of the New York Academy of Sciences 1982;399():105-11.
1982: J T Kung; S O Sharrow; C A Thomas; William Paul
Analysis of B lymphocyte differentiation antigens by flow microfluorometry.
Immunological reviews 1982;69():51-68.
1982: A L DeFranco; J T Kung; William Paul
Regulation of growth and proliferation in B cell subpopulations.
Immunological reviews 1982;64():161-82.
1982: William Paul; B Sredni; M Howard
Cell cloning as a tool to analyze the immune response.
National Cancer Institute monograph 1982;60():211-4.
1981: William Paul; B Sredni; R H Schwartz
Long-term growth and cloning of non-transformed lymphocytes.
Nature 1981;294(5843):697-9.
1981: B Sredni; D G Sieckmann; S Kumagai; S House; I Green; William Paul
Long-term culture and cloning of nontransformed human B lymphocytes.
The Journal of experimental medicine 1981;154(5):1500-16.
1981: William Paul
Clinical investigation--on the threshold of a golden era? Presidential address.
The Journal of clinical investigation 1981;68(3):823-6.
1981: M Howard; S Kessler; T Chused; William Paul
Long-term culture of normal mouse B lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(9):5788-92.
1981: J T Kung; S O Sharrow; D G Sieckmann; R Lieberman; William Paul
A mouse IgM allotypic determinant (Igh-6.5) recognized by a monoclonal rat antibody.
Journal of immunology (Baltimore, Md. : 1950) 1981;127(3):873-6.
1981: D G Sieckmann; R Habbersett; I Scher; William Paul
Activation of mouse lymphocytes by anti-immunoglobulin. III. Analysis of responding B lymphocytes by flow cytometry and cell sorting.
Journal of immunology (Baltimore, Md. : 1950) 1981;127(1):205-11.
1981: T T Hecht; William Paul
Replication of vesicular stomatitis virus in mouse spleen cells.
Infection and immunity 1981;32(3):1014-23.
1981: C A Bona; E Heber-Katz; William Paul
Idiotype-anti-idiotype regulation. I. Immunization with a levan-binding myeloma protein leads to the appearance of auto-anti-(anti-idiotype) antibodies and to the activation of silent clones.
The Journal of experimental medicine 1981;153(4):951-67.
1981: Harley Y Tse; J J Mond; William Paul
T lymphocyte-dependent B lymphocyte proliferative response to antigen. I Genetic restriction of the stimulation of B lymphocyte proliferation.
The Journal of experimental medicine 1981;153(4):871-82.
1981: B Sredni; L A Matis; E A Lerner; William Paul; R H Schwartz
Antigen-specific T cell clones restricted to unique F1 major histocompatibility complex determinants. Inhibition of proliferation with monoclonal anti-Ia antibody.
The Journal of experimental medicine 1981;153(3):677-93.
1981: Patricia Mongini; K E Stein; William Paul
T cell regulation of IgG subclass antibody production in response to T-independent antigens.
The Journal of experimental medicine 1981;153(1):1-12.
1980: V L Woods; I Scher; R Lieberman; William Paul
IgD allotypic determinants. II. Determinants expressed on IgD of mice of the b, e, and o Igh-C haplotypes.
Journal of immunology (Baltimore, Md. : 1950) 1980;125(6):2708-12.
1980: V L Woods; S W Kessler; F D Finkelman; R Lieberman; I Scher; William Paul
IgD allotypic determinants. I. Determinants expressed on murine IgD of the a allotype.
Journal of immunology (Baltimore, Md. : 1950) 1980;125(6):2699-707.
1980: J J Mond; M G Mage; T L Rothstein; D E Mosier; H Herrod; R Asofsky; William Paul
High anti-TNP plaque-forming cell potential of residual mIg+ cells in a T cell population.
Journal of immunology (Baltimore, Md. : 1950) 1980;125(4):1526-9.
1980: R H Schwartz; C Chen; William Paul
Gene complementation in the T lymphocyte proliferative response to poly (Glu56Lys35Phe9)n. Functional evidence for a restriction element coded for by both the I-A and I-E subregions.
European journal of immunology 1980;10(9):708-14.
1980: J J Mond; Patricia Mongini; D Sieckmann; William Paul
Role of T lymphocytes in the response to TNP-AECM-Ficoll.
Journal of immunology (Baltimore, Md. : 1950) 1980;125(3):1066-70.
1980: Harley Y Tse; R H Schwartz; William Paul
Cell-cell interactions in the T cell proliferative response. I. Analysis of the cell types involved and evidence for nonspecific T cell recruitment.
Journal of immunology (Baltimore, Md. : 1950) 1980;125(2):491-500.
1980: C Bona; Patricia Mongini; K E Stein; William Paul
Anti-immunoglobulin antibodies. I. Expression of cross-reactive idiotypes and Ir gene control of the response to IgG2a of the b allotype.
The Journal of experimental medicine 1980;151(6):1334-48.
1980: K E Stein; C Bona; R Lieberman; C C Chien; William Paul
Regulation of the anti-inulin antibody response by a nonallotype-linked gene.
The Journal of experimental medicine 1980;151(5):1088-102.
1980: A K Berning; E M Eicher; William Paul; I Scher
Mapping of the X-linked immune deficiency mutation (xid) of CBA/N mice.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(4):1875-7.
1980: J J Mond; S Kessler; F D Finkelman; William Paul; I Scher
Heterogeneity of Ia expression on normal B cells, neonatal B cells, and on cells from B cell-defective CBA/N mice.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(4):1675-82.
1980: K E Stein; C A Brennan; J J Mond; O Mäkelä; William Paul
Antibody affinity in mice with the CBA/N defect.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(4):1798-802.
1980: C Bona; J J Mond; William Paul
Synergistic genetic defect in B-lymphocyte function. I. Defective responses to B-cell stimulants and their genetic basis.
The Journal of experimental medicine 1980;151(1):224-34.
1979: C Bona; K E Stein; R Lieberman; William Paul
Direct and indirect suppression induced by anti-idiotype antibody in the inulin-bacterial levan antigenic system.
Molecular immunology 1979;16(12):1093-101.
1979: C Bona; J J Mond; K E Stein; S House; R Lieberman; William Paul
Immune response to levan. III. The capacity to produce anti-inulin antibodies and cross-reactive idiotypes appears late in ontogeny.
Journal of immunology (Baltimore, Md. : 1950) 1979;123(4):1484-90.
1979: J J Mond; E Sehgal; D H Sachs; William Paul
Expression of Ia antigen on adult and neonatal B lymphocytes responsive to thymus-independent antigens.
Journal of immunology (Baltimore, Md. : 1950) 1979;123(4):1619-23.
1979: J J Mond; K E Stein; B Subbarao; William Paul
Analysis of B cell activation requirements with TNP-conjugated polyacrylamide beads.
Journal of immunology (Baltimore, Md. : 1950) 1979;123(1):239-45.
1979: B Subbarao; A Ahmed; William Paul; I Scher; R Lieberman; D E Mosier
Lyb-7, a new B cell alloantigen controlled by genes linked to the IgCH locus.
Journal of immunology (Baltimore, Md. : 1950) 1979;122(6):2279-85.
1979: A Ahmed; B Subbarao; I Scher; J J Ryan; William Paul; D E Mosier; K W Sell
Preliminary evidence for a new non-H-2 locus that codes for lymphocyte-activating determinants distinct from Mls.
Transplantation proceedings 1979;11(2):1367-70.
1979: C Bona; R Lieberman; S House; I Green; William Paul
Immune response to levan. II. T independence of suppression of cross-reactive idiotypes by anti-idiotype antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1979;122(4):1614-9.
1979: R M Perlmutter; M Nahm; K E Stein; J Slack; I Zitron; William Paul; J M Davie
Immunoglobulin subclass-specific immunodeficiency in mice with an X-linked B-lymphocyte defect.
The Journal of experimental medicine 1979;149(4):993-8.
1979: C Bona; R Hooghe; P A Cazenave; C Leguérn; William Paul
Cellular basis of regulation of expression of idiotype. II. Immunity to anti-MOPC-460 idiotype antibodies increases the level of anti-trinitrophenyl antibodies bearing 460 idiotypes.
The Journal of experimental medicine 1979;149(4):815-23.
1979: C Bona; P A Cazenave; William Paul
Regulation of anti-TNP response by antiidiotypic and anti-(antiidiotypic) antibodies.
Annales d'immunologie 1979;130(2):303-9.
1979: R Lieberman; C Bona; C C Chien; K E Stein; William Paul
Genetic and cellular regulation of the expression of specific antibody idiotypes in the anti-polyfructosan immune response.
Annales d'immunologie 1979;130(2):247-62.
1979: C Bona; William Paul
Cellular basis of regulation of expression of idiotype. I. T-suppressor cells specific for MOPC 460 idiotype regulate the expression of cells secreting anti-TNP antibodies bearing 460 idiotype.
The Journal of experimental medicine 1979;149(3):592-600.
1979: B Subbarao; D E Mosier; A Ahmed; J J Mond; I Scher; William Paul
Role of a nonimmunoglobulin cell surface determinant in the activation of B lymphocytes by thymus-independent antigens.
The Journal of experimental medicine 1979;149(2):495-506.
1979: R H Schwartz; A Yano; J H Stimpfling; William Paul
Gene complementation in the T-lymphocyte proliferative response to poly (Glu55Lys36Phe9)n. A demonstration that both immune response gene products must be expressed in the same antigen-presenting cell.
The Journal of experimental medicine 1979;149(1):40-57.
1978: D G Sieckmann; I Scher; R Asofsky; D E Mosier; William Paul
Activation of mouse lymphocytes by anti-immunoglobulin. II. A thymus-independent response by a mature subset of B lymphocytes.
The Journal of experimental medicine 1978;148(6):1628-43.
1978: J J Mond; I Scher; D E Mosier; M Baese; William Paul
T-independent responses in B cell-defective CBA/N mice to Brucella abortus and to trinitrophenyl (TNP) conjugates of Brucella abortus.
European journal of immunology 1978;8(7):459-63.
1978: William Paul; I Scher; J J Mond; A A Ahmed; B Subbarao; D E Mosier
B lymphocyte development, heterogeneity, and function.
Arthritis and rheumatism 1978;21(5 Suppl):S175-9.
1978: A Yano; R H Schwartz; William Paul
Antigen presentation in the murine T lymphocyte proliferative response. II. Ir-GAT-controlled T lymphocyte responses require antigen-presenting cells from a high responder donor.
European journal of immunology 1978;8(5):344-7.
1978: R H Schwartz; Chella S David; M E Dorf; franccesca villella; William Paul
Inhibition of dual Ir gene-controlled T-lymphocyte proliferative response to poly (Glu56Lys35Phe9)n with anti-Ia antisera directed against products of either I-A or I-C subregion.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(5):2387-91.
1978: C Bona; R Lieberman; C C Chien; J Mond; S House; I Green; William Paul
Immune response to levan. I. Kinetics and ontogeny of anti-levan and anti-inulin antibody response and of expression of cross-reactive idiotype.
Journal of immunology (Baltimore, Md. : 1950) 1978;120(4):1436-42.
1978: D G Sieckmann; R Asofsky; D E Mosier; I M Zitron; William Paul
Activation of mouse lymphocytes by anti-immunoglobulin. I. Parameters of the proliferative response.
The Journal of experimental medicine 1978;147(3):814-29.
1978: R H Schwartz; A Yano; William Paul
Interaction between antigen-presenting cells and primed T lymphocytes: an assessment of Ir gene expression in the antigen-presenting cell.
Immunological reviews 1978;40():153-80.
1977: I M Zitron; D E Mosier; William Paul
The role of surface IgD in the response to thymic-independent antigens.
The Journal of experimental medicine 1977;146(6):1707-18.
1977: J J Mond; R Lieberman; J K Inman; D E Mosier; William Paul
Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers.
The Journal of experimental medicine 1977;146(4):1138-42.
1977: A Yano; R H Schwartz; William Paul
Antigen presentation in the murine T-lymphocyte proliferative response. I. Requirement for genetic identity at the major histocompatibility complex.
The Journal of experimental medicine 1977;146(3):828-43.
1977: D E Mosier; N M Zaldivar; E Goldings; J Mond; I Scher; William Paul
Formation of antibody in the newborn mouse: study of T-cell-independent antibody response.
The Journal of infectious diseases 1977;136 Suppl():S14-9.
1977: B D Schwartz; A M Kask; William Paul; A F Geczy; E M Shevach
The guinea pig I region. I. A structural and genetic analysis.
The Journal of experimental medicine 1977;146(2):547-60.
1977: William Paul; franccesca villella
Functional specificity of thymus- dependent lymphocytes.
Science (New York, N.Y.) 1977;195(4284):1293-300.
1977: William Paul; E M Shevach; S Pickeral; D W Thomas; A S Rosenthal
Independent populations of primed F1 guinea pig T lymphocytes respond to antigen-pulsed parental peritoneal exudate cells.
The Journal of experimental medicine 1977;145(3):618-30.
1977: R H Schwartz; C L Horton; William Paul
T-lymphocyte-enriched murine peritoneal exudate cells. IV. Genetic control of cross-stimulation at the T-cell level.
The Journal of experimental medicine 1977;145(2):327-43.
1977: D E Mosier; I M Zitron; J J Mond; A Ahmed; I Scher; William Paul
Surface immunoglobulin D as a functional receptor for a subclass of B lymphocytes.
Immunological reviews 1977;37():89-104.
1977: William Paul; E M Shevach; D W Thomas; S F Pickeral; A S Rosenthal
Genetic restriction in T-lymphocyte activation by antigen-pulse peritoneal exudate cells.
Cold Spring Harbor symposia on quantitative biology 1977;41 Pt 2():571-8.
1977: A Ahmed; I Scher; S O Sharrow; A H Smith; William Paul; D H Sachs; K W Sell
B-lymphocyte heterogeneity: development and characterization of an alloantiserum which distinguishes B-lymphocyte differentiation alloantigens.
The Journal of experimental medicine 1977;145(1):101-10.
1976: C A Janeway; William Paul
The specificity of cellular immune responses in guinea pigs. III. The precision of antigen recognition by T lymphocytes.
The Journal of experimental medicine 1976;144(6):1641-56.
1976: D E Mosier; I Scher; William Paul
In vitro responses of CBA/N mice: spleen cells of mice with an X-linked defect that precludes immune responses to several thymus-independent antigens can respond to TNP-lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 1976;117(4):1363-9.
1976: R H Schwartz; Chella S David; D H Sachs; William Paul
T lymphocyte-enriched murine peritoneal exudate cells. III. Inhibition of antigen-induced T lymphocyte Proliferation with anti-Ia antisera.
Journal of immunology (Baltimore, Md. : 1950) 1976;117(2):531-40.
1976: I Scher; S O Sharrow; William Paul
X-linked B-lymphocyte defect in CBA/N mice. III. Abnormal development of B-lymphocyte populations defined by their density of surface immunoglobulin.
The Journal of experimental medicine 1976;144(2):507-18.
1976: I Scher; S O Sharrow; R Wistar; R Asofsky; William Paul
B-lymphocyte heterogeneity: ontogenetic development and organ distribution of B-lymphocyte populations defined by their density of surface immunoglobulin.
The Journal of experimental medicine 1976;144(2):494-506.
1976: William Paul
Genetic control of specific interactions of immunocompetent cells. Speculations on mechanisms and general biologic significance.
Federation proceedings 1976;35(9):2044-7.
1976: F D Finkelman; J A van Boxel; R Asofsky; William Paul
Cell membrane IgD: demonstration of IgD on human lymphocytes by enzyme-catalyzed iodination and comparison with cell surface Ig of mouse, guinea pig, and rabbit.
Journal of immunology (Baltimore, Md. : 1950) 1976;116(4):1173-81.
1976: S Z Ben-Sasson; William Paul
Selection and enrichment of antigen-specific T lymphocyte populations.
Israel journal of medical sciences 1976;12(4-5):414-24.
1976: R H Schwartz; M E Dorf; franccesca villella; William Paul
The requirement for two complementing Ir-GLphi immune response genes in the T-lymphocyte proliferative response to poly-(Glu53Lys36Phe11).
The Journal of experimental medicine 1976;143(4):897-905.
1976: R H Schwartz; William Paul
T-lymphocyte-enriched murine peritoneal exudate cells. II. Genetic control of antigen-induced T-lymphocyte proliferation.
The Journal of experimental medicine 1976;143(3):529-40.
1976: B D Schwartz; A M Kask; William Paul; E M Shevach
Structural characteristics of the alloantigens determined by the major histocompatibility complex of the guinea pig.
The Journal of experimental medicine 1976;143(3):541-58.
1976: A Ahmed; I Scher; A Smith; William Paul; K W Sell
Studies on non-H-2 linked lymphocyte activating determinants. III. Influence of the X-chromosome and correlation of the density of surface Ig with the appearance of the MLs product [proceedings].
Folia biologica 1976;22(6):423-7.
1976: B D Schwartz; William Paul; E M Shevach
Guinea-pig Ia antigens: functional significance and chemical characterization.
Transplantation reviews 1976;30():174-96.
1975: S Z Ben-Sasson; William Paul; E M Shevach; I Green
In vitro selection and extended culture of antigen-specific T lymphocytes. II. Mechanisms of selection.
Journal of immunology (Baltimore, Md. : 1950) 1975;115(6):1723-30.
1975: F D Finkelman; A H Smith; I Scher; William Paul
Abnormal ratio of membrane immunoglobulin classes in mice with an X-linked B-lymphocyte defect.
The Journal of experimental medicine 1975;142(5):1316-21.
1975: R H Schwartz; L Jackson; William Paul
T lymphocyte-enriched murine peritoneal exudate cells. I. A reliable assay for antigen-induced T lymphocyte proliferation.
Journal of immunology (Baltimore, Md. : 1950) 1975;115(5):1330-8.
1975: I Scher; A D Steinberg; A K Berning; William Paul
X-linked B-lymphocyte immune defect in CBA/N mice. II. Studies of the mechanisms underlying the immune defect.
The Journal of experimental medicine 1975;142(3):637-50.
1975: S Z Ben-Sasson; William Paul; E M Shevach; I Green
In vitro selection and extended culture of antigen-specific T lymphocytes. I. Description of selection culture procedure and initial characterization of selected cells.
The Journal of experimental medicine 1975;142(1):90-105.
1975: M C Gelfand; William Paul
Prolongation of allograft survival in mice by administration of anti-Thy 1 serum. I. Mediation by in vivo activation of regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 1975;115(1):1-4.
1975: E Shevach; S Z Ben-Sasson; F Finkelman; William Paul; I Green
Mechanisms of action of genes controlling the immune response.
Transplantation proceedings 1975;7(2):141-7.
1975: R Sharon; P R McMaster; A M Kask; J D Owens; William Paul
DNP-Lys-ficoll: a T-independent antigen which elicits both IgM and IgG anti-DNP antibody-secreting cells.
Journal of immunology (Baltimore, Md. : 1950) 1975;114(5):1585-9.
1975: I Scher; A Ahmed; D M Strong; A D Steinberg; William Paul
X-linked B-lymphocyte immune defect in CBA/HN mice. I. Studies of the function and composition of spleen cells.
The Journal of experimental medicine 1975;141(4):788-803.
1975: E M Shevach; F Finkelman; S Z Ben-Sasson; I Green; William Paul
Ir genes and antigen recognition.
Annals of the New York Academy of Sciences 1975;249():541-7.
1975: William Paul; G J Elfenbein
An expression for the calculation of relative affinities of antibody-ligand interactions.
Journal of immunology (Baltimore, Md. : 1950) 1975;114(1 Pt 2):261-4.
1975: F D Findelman; E M Shevach; E S Vitetta; I Green; William Paul
Guinea pig immune response-related histocompatibility antigens. Partial characterization and distribution.
The Journal of experimental medicine 1975;141(1):27-41.
1975: C A Janeway; H S Koren; William Paul
The role of thymus-derived lymphocytes in an antibody-mediated hapten-specific helper effect.
European journal of immunology 1975;5(1):17-22.
1975: C A Janeway; B E Cohen; S Z Ben-Sasson; William Paul
The specificity of cellular immune responses in guinea pigs. I. T cells specific for 2,4-dinitrophenyl-o-tyrosyl residues.
The Journal of experimental medicine 1975;141(1):42-55.
1974: M C Gelfand; R Asofsky; William Paul
Ontogeny of B lymphocytes. I. In vitro appearance of Ig-bearing lymphocytes.
Cellular immunology 1974;14(3):460-9.
1974: J M Davie; William Paul
Role of T lymphocytes in the humoral immune response. I. Proliferation of B lymphocytes in thymus-deprived mice.
Journal of immunology (Baltimore, Md. : 1950) 1974;113(5):1438-45.
1974: S Z Ben-Sasson; E Shevach; I Green; William Paul
Alloantiserum-induced inhibition of migration inhibition factor production in immune response gene-controlled immune systems.
The Journal of experimental medicine 1974;140(2):383-95.
1974: J M Davie; William Paul; R Asofsky; R W Warren
Ontogeny of immunoglobulin-bearing lymphocytes and DNP-specific antigen-binding cells in guinea pigs.
Journal of immunology (Baltimore, Md. : 1950) 1974;112(6):2202-9.
1974: G J Elfenbein; I Green; William Paul
The allogeneic effect: increased cellular immune and inflammatory responses.
Journal of immunology (Baltimore, Md. : 1950) 1974;112(6):2166-75.
1974: D E Mosier; B M Johnson; William Paul; P R McMaster
Cellular requirements for the primary in vitro antibody response to DNP-ficoll.
The Journal of experimental medicine 1974;139(5):1354-60.
1974: M C Gelfand; D H Sachs; R Lieberman; William Paul
Ontogeny of B lymphocytes. 3. H-2 linkage of a gene controlling the rate of appearance of complement receptor lymphocytes.
The Journal of experimental medicine 1974;139(5):1142-53.
1974: M C Gelfand; G J Elfenbein; M M Frank; William Paul
Ontogeny of B lymphocytes. II. Relative rates of appearance of lymphocytes bearing surface immunoglobulin and complement receptors.
The Journal of experimental medicine 1974;139(5):1125-41.
1974: E M Shevach; I Green; William Paul
Alloantiserum-induced inhibition of immune response gene product function. II. Genetic analysis of target antigens.
The Journal of experimental medicine 1974;139(3):679-95.
1974: E M Shevach; William Paul; I Green
Alloantiserum-induced inhibition of immune response gene product function. I. Cellular distribution of target antigens.
The Journal of experimental medicine 1974;139(3):661-78.
1974: I Green; E M Shevach; William Paul
Antigen-T cell recognition: analysis by alloantisera-induced inhibition of immune response gene product function.
Journal of the Reticuloendothelial Society 1974;15(3):233-41.
1974: William Paul
Ontogeny and differentiation of thymus-independent lymphocytes.
Journal of the Reticuloendothelial Society 1974;15(3):242-6.
1974: J A Van Boxel; William Paul; I Green; M M Frank
Antibody-dependent lymphoid cell-mediated cytotoxicity: role of complement.
Journal of immunology (Baltimore, Md. : 1950) 1974;112(1):398-403.
1974: B E Cohen; William Paul
Macrophage control of time-dependent changes in antigen sensitivity of immune T lymphocyte populations.
Journal of immunology (Baltimore, Md. : 1950) 1974;112(1):359-69.
1974: William Paul; R Sharon; J M Davie; P R McMaster
Population changes in antigen-binding and antibody-secreting cells in the course of the immune response.
Society of General Physiologists series 1974;29():49-58.
1974: J M Davie; William Paul
Antigen-binding receptors on lymphocytes.
Contemporary topics in immunobiology 1974;3():171-92.
1974: R Lieberman; William Paul
Genetic control of antibody responses to myeloma proteins of mice.
Contemporary topics in immunobiology 1974;3():117-39.
1973: I Green; E M Shevach; William Paul
Inhibition of in vitro lymphocyte proliferation by alloantisera in genetically controlled immune systems in guinea pigs.
Transplantation proceedings 1973;5(4):1849-53.
1973: M R Harrison; William Paul
Stimulus-response in the mixed lymphocyte reaction.
The Journal of experimental medicine 1973;138(6):1602-7.
1973: J A van Boxel; John Hardin; I Green; William Paul
Multiple heavy-chain determinants on individual B lymphocytes in the peripheral blood of patients with Sjögren's syndrome.
The New England journal of medicine 1973;289(16):823-7.
1973: G J Elfenbein; I Green; William Paul
The allogeneic effect: increased affinity of serum antibody produced during a secondary response.
European journal of immunology 1973;3(10):640-4.
1973: B E Cohen; A S Rosenthal; William Paul
Antigen-macrophage interaction. I. Hapten-specific inhibition of antigen interaction with macrophages from immune animals.
Journal of immunology (Baltimore, Md. : 1950) 1973;111(3):811-9.
1973: B E Cohen; A S Rosenthal; William Paul
Antigen-macrophage interaction. II. Relative roles of cytophilic antibody and other membrane sites.
Journal of immunology (Baltimore, Md. : 1950) 1973;111(3):820-8.
1973: J D Stobo; A S Rosenthal; William Paul
Functional heterogeneity of murine lymphoid cells. V. Lymphocytes lacking detectable surface theta or immunoglobulin determinants.
The Journal of experimental medicine 1973;138(1):71-88.
1973: C A Janeway; William Paul
Hapten-specific augmentation of the anti-idiotype antibody response to hapten-myeloma protein conjugates in mice.
European journal of immunology 1973;3(6):340-7.
1973: J D Stobo; William Paul; C S Henney
Functional heterogeneity of murine lymphoid cells. IV. Allogeneic mixed lymphocyte reactivity and cytolytic activity as functions of distinct T cell subsets.
Journal of immunology (Baltimore, Md. : 1950) 1973;110(3):652-60.
1973: J D Stobo; William Paul
Functional heterogeneity of murine lymphoid cells. 3. Differential responsiveness of T cells to phytohemagglutinin and concanavalin A as a probe for T cell subsets.
Journal of immunology (Baltimore, Md. : 1950) 1973;110(2):362-75.
1973: J M Davie; William Paul
Immunological maturation. Preferential proliferation of high-affinity precursor cells.
The Journal of experimental medicine 1973;137(1):201-4.
1973: J D Stobo; William Paul
Functional heterogeneity of thymus-derived lymphocytes.
Advances in experimental medicine and biology 1973;29(0):113-8.
1973: B E Cohen; J M Davie; William Paul
Hapten-specific tolerance: depressed humoral and normal cellular immune responses.
Journal of immunology (Baltimore, Md. : 1950) 1973;110(1):213-8.
1973: D H Katz; William Paul; franccesca villella
Carrier function in anti-hapten antibody responses. VI. Establishment of experimental conditions for either inhibitory or enhancing influences of carrier-specific cells on antibody production.
Journal of immunology (Baltimore, Md. : 1950) 1973;110(1):107-17.
1972: William Paul
Immunogenicity--heterogenization and problems of antigen recognition.
National Cancer Institute monograph 1972;35():285-7.
1972: E M Shevach; William Paul; I Green
Histocompatibility-linked immune response gene function in guinea pigs. Specific inhibition of antigen-induced lymphocyte proliferation by alloantisera.
The Journal of experimental medicine 1972;136(5):1207-21.
1972: R Lieberman; William Paul; W Humphrey; J H Stimpfling
H-2-linked immune response (Ir) genes. Independent loci for Ir-IgG and Ir-IgA genes.
The Journal of experimental medicine 1972;136(5):1231-40.
1972: J D Stobo; N Talal; William Paul
Lymphocyte classes in New Zealand mice. II. Decreased frequency of immunoglobulin-bearing lymphocytes and increased frequency of lymphocytes lacking detectable theta or immunoglobulin determinants.
Journal of immunology (Baltimore, Md. : 1950) 1972;109(4):701-10.
1972: J D Stobo; N Talal; William Paul
Lymphocyte classes in New Zealand mice. I. Ontogeny and mitogen responsiveness of thymocytes and thymus-derived lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1972;109(4):692-700.
1972: I Green; William Paul; franccesca villella
Histocompatibility-linked genetic control of the immune response to hapten guinea pig albumin conjugates in inbred guinea pigs.
Journal of immunology (Baltimore, Md. : 1950) 1972;109(3):457-63.
1972: J M Davie; William Paul; D H Katz; franccesca villella
Hapten-specific tolerance. Preferential depression of the high affinity antibody response.
The Journal of experimental medicine 1972;136(3):426-38.
1972: J A Van Boxel; William Paul; W D Terry; I Green
Communications. IgD-bearing human lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1972;109(3):648-51.
1972: J M Davie; William Paul; I Green
Genetic control of the immune response of inbred guinea pigs to 2,4-dinitrophenyl guinea pig albumin. Frequency of antigen-binding lymphocytes and avidity of antibodies secreted by plaque-forming cells.
Journal of immunology (Baltimore, Md. : 1950) 1972;109(2):193-200.
1972: J D Stobo; William Paul
Functional heterogeneity of murine lymphoid cells. II. Acquisition of mitogen responsiveness and of theta antigen during the ontogeny of thymocytes and "T" lymphocytes.
Cellular immunology 1972;4(4):367-80.
1972: T Yoshida; C A Janeway; William Paul
Activity of migration inhibitory factor in the absence of antigen.
Journal of immunology (Baltimore, Md. : 1950) 1972;109(2):201-6.
1972: J M Davie; William Paul
Receptors on immunocompetent cells. V. Cellular correlates of the "maturation" of the immune response.
The Journal of experimental medicine 1972;135(3):660-74.
1972: J M Davie; William Paul
Receptors on immunocompetent cells. IV. Direct measurement of avidity of cell receptors and cooperative binding of multivalent ligands.
The Journal of experimental medicine 1972;135(3):643-59.
1972: J A Van Boxel; J D Stobo; William Paul; I Green
Antibody-dependent lymphoid cell-mediated cytotoxicity: no requirement for thymus-derived lymphocytes.
Science (New York, N.Y.) 1972;175(4018):194-6.
1972: J D Stobo; A S Rosenthal; William Paul
Functional heterogeneity of murine lymphoid cells. I. Responsiveness to and surface binding of concanavalin A and phytohemagglutinin.
Journal of immunology (Baltimore, Md. : 1950) 1972;108(1):1-17.
1972: L Ellman; D H Katz; I Green; William Paul; franccesca villella
Mechanisms involved in the antileukemic effect of immunocompetent allogeneic lymphoid cell transfer.
Cancer research 1972;32(1):141-8.
1972: D H Katz; L Ellman; William Paul; I Green; franccesca villella
Resistance of guinea pigs to leukemia following transfer of immunocompetent allogeneic lymphoid cells.
Cancer research 1972;32(1):133-40.
1971: D H Katz; William Paul; franccesca villella
Carrier function in anti-hapten antibody responses. V. Analysis of cellular events in the enhancement of antibody responses by the "allogeneic effect" in DNP-OVA-primed guinea pigs challenged with a heterologous DNP-conjugate.
Journal of immunology (Baltimore, Md. : 1950) 1971;107(5):1319-28.
1971: Y Stupp; William Paul; franccesca villella
Structural control of immunogenicity. II. Antibody synthesis and cellular immunity in response to immunization with mono-epsilon-oligo-L-lysines.
Immunology 1971;21(4):583-94.
1971: William Paul; A M Kask
Structural control of immunogenicity. I. Synthesis of oligo-L-lysine peptides and their mono-epsilon-DNP derivatives.
Immunology 1971;21(4):575-82.
1971: William Paul; Y Stupp; G W Siskind; franccesca villella
Structural control of immunogenicity. IV. Relative specificity of elicitation of cellular immune responses and of ligand binding to anti-hapten antibody after immunization with mono-epsilon-DNP-nona-L-lysine.
Immunology 1971;21(4):605-16.
1971: Y Stupp; William Paul; franccesca villella
Structural control of immunogenicity. 3. Preparation for and elicitation of anamnestic antibody responses by oligo- and poly-lysines and their DNP derivatives.
Immunology 1971;21(4):595-603.
1971: William Paul; D H Katz; franccesca villella
Augmented anti-S 3 antibody responses to an S 3 -protein conjugate.
Journal of immunology (Baltimore, Md. : 1950) 1971;107(3):685-8.
1971: J M Davie; A S Rosenthal; William Paul
Receptors on immunocompetent cells. 3. Specificity and nature of receptors on dinitrophenylated guinea pig albumin- 125 I-binding cells of immunized guinea pigs.
The Journal of experimental medicine 1971;134(2):517-31.
1971: J M Davie; William Paul
Receptors on immunocompetent cells. II. Specificity and nature of receptors on dinitrophenylated guinea pig albumin- 125 I-binding lymphocytes of normal guinea pigs.
The Journal of experimental medicine 1971;134(2):495-516.
1971: D H Katz; J M Davie; William Paul; franccesca villella
Carrier function in anti-hapten antibody responses. IV. Experimental conditions for the induction of hapten-specific tolerance or for the stimulation of anti-hapten anamnestic responses by "nonimmunogenic" hapten-polypeptide conjugates.
The Journal of experimental medicine 1971;134(1):201-23.
1971: R K Gershon; William Paul
Effect of thymus-derived lymphocytes on amount and affinity of anti-hapten antibody.
Journal of immunology (Baltimore, Md. : 1950) 1971;106(3):872-4.
1971: D H Katz; William Paul; E A Goidl; franccesca villella
Carrier function in anti-hapten antibody responses. 3. Stimulation of antibody synthesis and facilitation of hapten-specific secondary antibody responses by graft-versus-host reactions.
The Journal of experimental medicine 1971;133(2):169-86.
1971: J M Davie; William Paul; R G Mage; M B Goldman
Membrane-associated immunoglobulin of rabbit peripheral blood lymphocytes: allelic exclusion at the b locus.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(2):430-4.
1971: J P Lamelin; William Paul
Rate of increase of antibody affinity in different rat strains.
International archives of allergy and applied immunology 1971;40(3):351-60.
1970: D H Katz; William Paul; E A Goidl; franccesca villella
Radioresistance of cooperative function of carrier-specific lymphocytes in antihapten antibody responses.
Science (New York, N.Y.) 1970;170(3956):462-4.
1970: J M Davie; William Paul
Receptors on immunocompetent cells. I. Receptor specificity of cells participating in a cellular immune response.
Cellular immunology 1970;1(4):404-18.
1970: William Paul; T Yoshida; franccesca villella
Genetic control of the specificity of anti-DNP antibodies. II. Differences in the specificity of anti-DNP antibody produced by several inbred strains of mice.
Journal of immunology (Baltimore, Md. : 1950) 1970;105(2):314-21.
1970: T Yoshida; William Paul; franccesca villella
Genetic control of the specificity of anti-DNP antibodies. I. Differences in the specificity of anti-DNP antibody produced by mammalian species.
Journal of immunology (Baltimore, Md. : 1950) 1970;105(2):306-13.
1970: William Paul; D H Katz; E A Goidl; franccesca villella
Carrier function in anti-hapten immune responses. II. Specific properties of carrier cells capable of enhancing anti-hapten antibody responses.
The Journal of experimental medicine 1970;132(2):283-99.
1970: D H Katz; William Paul; E A Goidl; franccesca villella
Carrier function in anti-hapten immune responses. I. Enhancement of primary and secondary anti-hapten antibody responses by carrier preimmunization.
The Journal of experimental medicine 1970;132(2):261-82.
1970: William Paul; G W Siskind
Hapten specificity of cellular immune responses as compared with the specificity of serum anti-hapten antibody.
Immunology 1970;18(6):921-30.
1970: T C Francis; William Paul
Inhibition by hapten of cellular immune responses to a hapten-protein conjugate.
Nature 1970;226(5241):173-4.
1970: franccesca villella; William Paul; I Green
Hapten-carrier relationships.
Annals of the New York Academy of Sciences 1970;169(1):93-104.
1970: William Paul
Determinant specificity of cellular immune responses.
Federation proceedings 1970;29(1):224-5.
1970: D Mancino; William Paul; franccesca villella; G W Siskind; Z Ovary
Binding properties of anti-dinitrophenylated-bacitracin A antibodies produced in guinea pigs.
Journal of immunology (Baltimore, Md. : 1950) 1970;104(1):224-9.
1970: William Paul
Functional specificity of antigen-binding receptors of lymphocytes.
Transplantation reviews 1970;5():130-66.
1969: I Green; William Paul; franccesca villella
Genetic control of immunological responsiveness in guinea pigs to 2,4-dinitrophenyl conjugates of poly-L-arginine, protamine, and poly-L-ornithine.
Proceedings of the National Academy of Sciences of the United States of America 1969;64(3):1095-102.
1969: Y Stupp; T Yoshida; William Paul
Determination of antibody-hapten equilibrium constants by an ammonium sulfate precipitation technique.
Journal of immunology (Baltimore, Md. : 1950) 1969;103(3):625-7.
1969: William Paul; G J Thorbecke; G W Siskind; franccesca villella
The effect of dose in tolerance induction on the subsequent response to a cross-reactive antigen.
Immunology 1969;17(1):85-92.
1969: William Paul; franccesca villella; G W Siskind; D A Goidl; R A Reisfeld
The anamnestic antibody response to type 3 specific pneumococcal polysaccharide.
The Journal of experimental medicine 1969;130(1):77-89.
1968: William Paul; I Green; franccesca villella
Genetic control of the immune response to hapten-poly-L-lysine conjugates.
Journal of the Reticuloendothelial Society 1968;5(3):282-93.
1968: J P Lamelin; William Paul; franccesca villella
The immune response of random-bred Hartley strain guinea pigs to 2,4-dinitrophenyl conjugates of a copolymer of L-glutamic acid and L-lysine.
Journal of immunology (Baltimore, Md. : 1950) 1968;100(5):1058-61.
1968: E A Goidl; William Paul; G W Siskind; franccesca villella
The effect of antigen dose and time after immunization on the amount and affinity of anti-hapten antibody.
Journal of immunology (Baltimore, Md. : 1950) 1968;100(2):371-5.
1968: I Green; William Paul; franccesca villella
Hapten carrier relationships in the DNP-PLL foreign albumin complex system: induction of tolerance and stimulation of cells in vitro.
The Journal of experimental medicine 1968;127(1):43-53.
1968: William Paul; G W Siskind; franccesca villella
Specificity of cellular immune responses. Antigen concentration dependence of stimulation of DNA synthesis in vitro by specifically sensitized cells, as an expression of the binding characteristics of cellular antibody.
The Journal of experimental medicine 1968;127(1):25-42.
1967: I Green; William Paul; franccesca villella
A study of the passive transfer of delayed hypersensitivity to DNP-poly-L-lysine and DNP-GL in responder and nonresponder guinea pigs.
The Journal of experimental medicine 1967;126(5):959-67.
1967: William Paul; G W Siskind; franccesca villella; Z Ovary
Secondary antibody responses in haptenic systems: cell population selection by antigen.
Journal of immunology (Baltimore, Md. : 1950) 1967;99(4):760-70.
1967: William Paul; G W Siskind; franccesca villella
A study of the 'termination' of tolerance to BSA with DNP-BSA in rabbits: relative affinities of the antibodies for the immunizing and the paralysing antigens.
Immunology 1967;13(2):147-57.
1966: I Green; William Paul; franccesca villella
The behavior of hapten-poly-L-lysine conjugates as complete antigens in genetic responder and as haptens in nonresponder guinea pigs.
The Journal of experimental medicine 1966;123(5):859-79.
1966: William Paul; G W Siskind; franccesca villella
Studies on the effect of the carrier molecule on antihapten antibody synthesis. II. Carrier specificity of anti-2,4-dinitrophenyl-poly-l-lysine antibodies.
The Journal of experimental medicine 1966;123(4):689-705.
1966: G W Siskind; William Paul; franccesca villella
Studies on the effect of the carrier molecule on antihapten antibody synthesis. I. Effect of carrier on the nature of the antibody synthesized.
The Journal of experimental medicine 1966;123(4):673-88.
1965: William Paul; franccesca villella
Problems encountered in double diffusion analysis in agar of hapten specific immune systems. II. The effect of the relative solubility of the immune complexes formed by cross-reacting systems.
Journal of immunology (Baltimore, Md. : 1950) 1965;95(6):1074-9.
1965: William Paul; franccesca villella
Problems encountered in double diffusion analysis in agar of hapten specific immune systems. I. Complement dependent precipitation.
Journal of immunology (Baltimore, Md. : 1950) 1965;95(6):1067-73.
1965: W D Odell; J F Wilber; William Paul
Radioimmunoassay of thyrotropin in human serum.
The Journal of clinical endocrinology and metabolism 1965;25(9):1179-88.
1965: W D ODELL; William Paul
RADIATION INACTIVATION OF BIOLOGICAL AND IMMUNOLOGICAL ACTIVITIES OF BEEF THYROTROPIN.
The Journal of biological chemistry 1965;240():2043-6.
1965: William Paul; A J KASTIN; W D ODELL
THE EFFECT OF IONIZING RADIATION ON MELANOCYTE-STIMULATING AND STEROIDOGENIC ACTIVITIES OF CORTICOTROPIN.
Biochimica et biophysica acta 1965;100():263-9.
1965: W D ODELL; J F WILBER; William Paul
RADIOIMMUNOASSAY OF HUMAN THYROTROPIN IN SERUM.
Metabolism: clinical and experimental 1965;14():465-7.
1964: William Paul; G T ROSS
IMMUNOLOGIC CROSS-REACTION BETWEEN HUMAN CHORIONIC GONADOTROPIN AND HUMAN PITUITARY GONADOTROPIN.
Endocrinology 1964;75():352-8.
1964: William Paul; W D ODELL
RADIATION INACTIVATION OF THE IMMUNOLOGICAL AND BIOLOGICAL ACTIVITIES OF HUMAN CHORIONIC GONADOTROPIN.
Nature 1964;203():979-80.
1963: William Paul; A S COHEN
ELECTRON MICROSCOPIC STUDIES OF AMYLOID FIBRILS WITH FERRITINCONJUGATED ANTIBODY.
The American journal of pathology 1963;43():721-38.
1963: A S COHEN; William Paul
Relationship of gamma-globulin to the fibrils of secondary human amyloid.
Nature 1963;197():193-4.