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Michitaka Ozaki
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17
Irani, Kaikobad
11
Iwagaki, Hiromi
8
Tanaka, Noriaki
7
Enosawa, Shin
6
Haga, Sanae
6
Sadamori, Hiroshi
6
Todo, Satoru
6
Yagi, Takahito
5
Teraoka, Satoshi
5
Terui, Keita
5
Ogino, Tetsuya
5
Deshpande, Shailesh
5
Angkeow, Piamsook
4
Fuchinoue, Shohei
4
Lowenstein, Charles
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All Publications
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2009: Umeda Y; Iwagaki H; Ozaki M; Ogino T; Iwamoto T; Yoshida R; Shinoura S; Matsuda H; Sadamori H; Tanaka N; Yagi T
Refractory response to growth factors impairs liver regeneration after hepatectomy in patients with viral hepatitis.
Hepato-gastroenterology 2009;56(93):971-7.
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2009: Ikeda Osamu; Ozaki Michitaka; Murata Soichiro; Matsuo Ryota; Nakano Yoritaka; Watanabe Motonobu; Hisakura Katsuji; Myronovych Andriy; Kawasaki Takuya; Kohno Keisuke; Ohkohchi Nobuhiro
Autonomic regulation of liver regeneration after partial hepatectomy in mice.
The Journal of surgical research 2009;152(2):218-23.
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2009: Haga Sanae; Ozaki Michitaka; Inoue Hiroshi; Okamoto Yasuo; Ogawa Wataru; Takeda Kiyoshi; Akira Shizuo; Todo Satoru
The survival pathways phosphatidylinositol-3 kinase (PI3-K)/phosphoinositide-dependent protein kinase 1 (PDK1)/Akt modulate liver regeneration through hepatocyte size rather than proliferation.
Hepatology (Baltimore, Md.) 2009;49(1):204-14.
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2009: Ogino Tetsuya; Ozaki Michitaka; Hosako Mutsumi; Omori Masako; Okada Shigeru; Matsukawa Akihiro
Activation of c-Jun N-terminal kinase is essential for oxidative stress-induced Jurkat cell apoptosis by monochloramine.
Leukemia research 2009;33(1):151-8.
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2009: Ogino Tetsuya; Than Tin Aung; Hosako Mutsumi; Ozaki Michitaka; Omori Masako; Okada Shigeru
Taurine chloramine: a possible oxidant reservoir.
Advances in experimental medicine and biology 2009;643():451-61.
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2008: Yimin; Kohanawa Masashi; Ozaki Michitaka; Haga Sanae; Fujikawa Keiko; Zhao Songji; Kuge Yuji; Tamaki Nagara
Mutual modulation between interleukin-10 and interleukin-6 induced by Rhodococcus aurantiacus infection in mice.
Microbes and infection / Institut Pasteur 2008;10(14-15):1450-8.
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2008: Suzuki Tomomi; Yamashita Kenichiro; Jomen Wataru; Ueki Shinya; Aoyagi Takeshi; Fukai Moto; Furukawa Hiroyuki; Umezawa Kazuo; Ozaki Michitaka; Todo Satoru
The novel NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin, prevents local and remote organ injury following intestinal ischemia/reperfusion in rats.
The Journal of surgical research 2008;149(1):69-75.
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2008: Watanabe Etsuko; Mochizuki Nobuo; Ajima Hidetomo; Ohno Keiko; Shiino Mitsuhiro; Umezawa Kazuo; Fukai Moto; Ozaki Michitaka; Furukawa Hiroyuki; Todo Satoru; Kishino Satoshi
A simple and reliable method for determining plasma concentration of dehydroxymethylepoxyquinomicin by high performance liquid chromatography with mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;871(1):32-6.
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2008: Gotohda Naoto; Iwagaki Hiromi; Ozaki Michitaka; Kinoshita Taira; Konishi Masaru; Nakagohri Toshio; Takahashi Shinichiro; Saito Shinya; Yagi Takahito; Tanaka Noriaki
Deficient response of IL-6 impaired liver regeneration after hepatectomy in patients with viral hepatitis.
Hepato-gastroenterology 2008;55(85):1439-44.
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2008: Gotohda Naoto; Iwagaki Hiromi; Ozaki Michitaka; Kinoshita Taira; Konishi Masaru; Nakagohri Toshio; Takahashi Shinichiro; Saito Shinya; Yagi Takahito; Tanaka Noriaki
Significant correlation between surgical stress of hepatectomy and changes in the serum levels of HGF, IL-6 and soluble Fas in patients with viral hepatitis.
Hepato-gastroenterology 2008;55(85):1400-3.
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2008: Ozaki Michitaka
[Role of jak/STAT3 and PI3-K/Akt pathways in liver injury and regeneration]
Seikagaku. The Journal of Japanese Biochemical Society 2008;80(5):399-408.
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2008: Zhang Hui-Qi; Haga Sanae; Fukai Moto; Oikawa Yuko; Inoue Hiroshi; Ogawa Wataru; Kano Arihiko; Maruyama Atsushi; Fu Xin-Yuan; Todo Satoru; Enosawa Shin; Ozaki Michitaka
Identification of de novo STAT3 target gene in liver regeneration.
Hepatology research : the official journal of the Japan Society of Hepatology 2008;38(4):374-84.
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2008: Matsuo Ryota; Ohkohchi Nobuhiro; Murata Soichiro; Ikeda Osamu; Nakano Yoritaka; Watanabe Motonobu; Hisakura Katsuji; Myronovych Andriy; Kubota Tomomi; Narimatsu Hisashi; Ozaki Michitaka
Platelets Strongly Induce Hepatocyte Proliferation with IGF-1 and HGF In Vitro.
The Journal of surgical research 2008;145(2):279-86.
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2008: Haga Sanae; Terui Keita; Fukai Moto; Oikawa Yuko; Irani Kaikobad; Furukawa Hiroyuki; Todo Satoru; Ozaki Michitaka
Preventing hypoxia/reoxygenation damage to hepatocytes by p66(shc) ablation: up-regulation of anti-oxidant and anti-apoptotic proteins.
Journal of hepatology 2008;48(3):422-32.
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2008: Miura Yoshiaki; Hato Megumi; Shinohara Yasuro; Kuramoto Hiromitsu; Furukawa Jun-ichi; Kurogochi Masaki; Shimaoka Hideyuki; Tada Mitsuhiro; Nakanishi Kazuaki; Ozaki Michitaka; Todo Satoru; Nishimura Shin-Ichiro
BlotGlycoABCTM, an integrated glycoblotting technique for rapid and large scale clinical glycomics.
Molecular & cellular proteomics : MCP 2008;7(2):370-7.
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2007: Ozaki Michitaka; Todo Satoru
Surgical stress and tumor behavior: impact of ischemia-reperfusion and hepatic resection on tumor progression.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2007;13(12):1623-6.
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2007: Murata Hiroshi; Yagi Takahito; Iwagaki Hiromi; Ogino Tetsuya; Sadamori Hiroshi; Matsukawa Hiroyoshi; Umeda Yuzoh; Haga Sanae; Takaka Noriaki; Ozaki Michitaka
Mechanism of impaired regeneration of fatty liver in mouse partial hepatectomy model.
Journal of gastroenterology and hepatology 2007;22(12):2173-80.
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2007: Oyama Takanori; Sadamori Hiroshi; Matsukawa Hiroyoshi; Murata Hiroshi; Umeda Yuzou; Watanabe Yasuhiro; Ozaki Michitaka; Iwagaki Hiromi; Tanaka Noriaki; Yagi Takahito
Small liver graft regenerates through immediate increase of HGF and IL-6--possible involvement of sinusoidal tensile/shear stress in small liver graft.
Hepato-gastroenterology 2007;54(79):2078-83.
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2006: Ueki Shinya; Yamashita Kenichiro; Aoyagi Takeshi; Haga Sanae; Suzuki Tomomi; Itoh Tomoo; Taniguchi Masahiko; Shimamura Tsuyoshi; Furukawa Hiroyuki; Ozaki Michitaka; Umezawa Kazuo; Todo Satoru
Control of allograft rejection by applying a novel nuclear factor-kappaB inhibitor, dehydroxymethylepoxyquinomicin.
Transplantation 2006;82(12):1720-7.
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2006: Miyaso Hideaki; Morimoto Yoshinori; Ozaki Michitaka; Haga Sanae; Shinoura Susumu; Choda Yasuhiro; Murata Hiroshi; Katsuno Goutaro; Huda Kamul; Takahashi Hideo; Tanaka Noriaki; Iwagaki Hiromi
Protective effects of nafamostat mesilate on liver injury induced by lipopolysaccharide in rats: possible involvement of CD14 and TLR-4 downregulation on Kupffer cells.
Digestive diseases and sciences 2006;51(11):2007-12.
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2006: Kamiyama Toshiya; Takahashi Masato; Nakagawa Takahito; Nakanishi Kazuaki; Kamachi Hirofumi; Suzuki Tomomi; Shimamura Tsuyoshi; Taniguchi Masahiko; Ozaki Michitaka; Matsushita Michiaki; Furukawa Hiroyuki; Todo Satoru
AFP mRNA detected in bone marrow by real-time quantitative RT-PCR analysis predicts survival and recurrence after curative hepatectomy for hepatocellular carcinoma.
Annals of surgery 2006;244(3):451-63.
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2006: Huda Kamrul A S M; Guo Lei; Haga Sanae; Murata Hiroshi; Ogino Tetsuya; Fukai Moto; Yagi Takahito; Iwagaki Hiromi; Tanaka Noriaki; Ozaki Michitaka
Ex vivo adenoviral gene transfer of constitutively activated STAT3 reduces post-transplant liver injury and promotes regeneration in a 20% rat partial liver transplant model.
Transplant international : official journal of the European Society for Organ Transplantation 2006;19(5):415-23.
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2006: Hiramatsu Kazuhisa; Ogino Tetsuya; Ozaki Michitaka; Okada Shigeru
Monochloramine inhibits ultraviolet B-induced p53 activation and DNA repair response in human fibroblasts.
Biochimica et biophysica acta 2006;1763(2):188-96.
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2006: Gotohda Naoto; Iwagaki Hiromi; Ozaki Michitaka; Konishi Masaru; Nakagohri Toshio; Takahashi Shinichiro; Yagi Takahito; Kinoshita Taira; Tanaka Noriaki
The role of a protease inhibitor against hepatectomy.
Hepato-gastroenterology 2006;53(67):115-9.
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2006: Tsukiyama Shusaku; Matsushita Michiaki; Matsumoto Shuichiro; Morita Tsunehiko; Kobayashi Satoru; Tamura Hitosi; Kamachi Hirohumi; Ozaki Michitaka; Todo Satoru
Transduction of exogenous constitutively activated Stat3 into dispersed islets induces proliferation of rat pancreatic beta-cells.
Tissue engineering 2006;12(1):131-40.
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2005: Ogino Tetsuya; Hosako Mutsumi; Hiramatsu Kazuhisa; Omori Masako; Ozaki Michitaka; Okada Shigeru
Oxidative modification of IkappaB by monochloramine inhibits tumor necrosis factor alpha-induced NF-kappaB activation.
Biochimica et biophysica acta 2005;1746(2):135-42.
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2005: Miyaso Hideaki; Morimoto Yoshinori; Ozaki Michitaka; Haga Sanae; Shinoura Susumu; Choda Yasuhiro; Iwagaki Hiromi; Tanaka Noriaki
Obstructive jaundice increases sensitivity to lipopolysaccharide via TLR4 upregulation: possible involvement in gut-derived hepatocyte growth factor-protection of hepatocytes.
Journal of gastroenterology and hepatology 2005;20(12):1859-66.
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2005: Maemura Kosei; Zheng Qizhi; Wada Tatehiko; Ozaki Michitaka; Takao Sonshin; Aikou Takashi; Bulkley Gregory B; Klein Andrew S; Sun Zhaoli
Reactive oxygen species are essential mediators in antigen presentation by Kupffer cells.
Immunology and cell biology 2005;83(4):336-43.
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2005: Terui Keita; Ozaki Michitaka
The role of STAT3 in liver regeneration.
Drugs of today (Barcelona, Spain : 1998) 2005;41(7):461-9.
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2005: Fujimoto Yoshimi; Iwagaki Hiromi; Ozaki Michitaka; Ogino Tetsuya; Murata Hiroshi; Sun Dong Sheng; Sadamori Hiroshi; Takahashi Hideo Kohka; Tanaka Noriaki; Yagi Takahito
Involvement of prostaglandin receptors (EPR2-4) in in vivo immunosuppression of PGE2 in rat skin transplant model.
International immunopharmacology 2005;5(7-8):1131-9.
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2005: Yang Xiao Ping; Irani Kaikobad; Mattagajasingh Subhendra; Dipaula Anthony; Khanday Firdous; Ozaki Michitaka; Fox-Talbot Karen; Baldwin William M; Becker Lewis C
Signal transducer and activator of transcription 3alpha and specificity protein 1 interact to upregulate intercellular adhesion molecule-1 in ischemic-reperfused myocardium and vascular endothelium.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(7):1395-400.
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2005: Sheng Sun Dong; Iwagaki Hiromi; Ozaki Michitaka; Ogino Tetsuya; Kusaka Satoshi; Fujimoto Yoshimi; Murata Hiroshi; Sadamori Hiroshi; Matsukawa Hiroyoshi; Tanaka Noriaki; Yagi Takahito
Prolonged survival of donor-specific rat intestinal allograft by administration of bone-marrow-derived immature dendritic cells.
Transplant immunology 2005;14(1):17-20.
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2005: Matsushita Kenji; Yamakuchi Munekazu; Morrell Craig N; Ozaki Michitaka; O'Rourke Brian; Irani Kaikobad; Lowenstein Charles J
Vascular endothelial growth factor regulation of Weibel-Palade-body exocytosis.
Blood 2005;105(1):207-14.
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2005: Hoentjen Frank; Sartor R Balfour; Ozaki Michitaka; Jobin Christian
STAT3 regulates NF-kappaB recruitment to the IL-12p40 promoter in dendritic cells.
Blood 2005;105(2):689-96.
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2004: Terui Keita; Enosawa Shin; Haga Sanae; Zhang Hui Qi; Kuroda Hiroaki; Kouchi Katsunori; Matsunaga Tadashi; Yoshida Hideo; Engelhardt John F; Irani Kaikobad; Ohnuma Naomi; Ozaki Michitaka
Stat3 confers resistance against hypoxia/reoxygenation-induced oxidative injury in hepatocytes through upregulation of Mn-SOD.
Journal of hepatology 2004;41(6):957-65.
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2004: Mitsuoka Naoshi; Iwagaki Hiromi; Ozaki Michitaka; Sheng Sun Dong; Sadamori Hiroshi; Matsukawa Hiroyoshi; Morimoto Yoshinori; Matsuoka Junji; Tanaka Noriaki; Yagi Takahito
The impact of portal infusion with donor-derived bone marrow cells and intracellular cytokine expression of graft-infiltrating lymphocytes on the graft survival in rat small bowel transplant model.
Transplant immunology 2004;13(3):155-60.
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2004: Jeon Byeong Hwa; Gupta Gaurav; Park Young Chul; Qi Bing; Haile Azeb; Khanday Firdous A; Liu Yan-Xia; Kim Jin-Man; Ozaki Michitaka; White Anthony R; Berkowitz Dan E; Irani Kaikobad
Apurinic/apyrimidinic endonuclease 1 regulates endothelial NO production and vascular tone.
Circulation research 2004;95(9):902-10.
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2004: Guo Lei; Haga Sanae; Enosawa Shin; Naruse Katsutoshi; Harihara Yasushi; Sugawara Yasuhiko; Irani Kaikobad; Makuuchi Masatoshi; Ozaki Michitaka
Improved hepatic regeneration with reduced injury by redox factor-1 in a rat small-sized liver transplant model.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(6):879-87.
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2004: Terui Keita; Haga Sanae; Enosawa Shin; Ohnuma Naomi; Ozaki Michitaka
Hypoxia/re-oxygenation-induced, redox-dependent activation of STAT1 (signal transducer and activator of transcription 1) confers resistance to apoptotic cell death via hsp70 induction.
The Biochemical journal 2004;380(Pt 1):203-9.
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2004: Inoue Hiroshi; Ogawa Wataru; Ozaki Michitaka; Haga Sanae; Matsumoto Michihiro; Furukawa Kensuke; Hashimoto Naoko; Kido Yoshiaki; Mori Toshiyuki; Sakaue Hiroshi; Teshigawara Kiyoshi; Jin Shiyu; Iguchi Haruhisa; Hiramatsu Ryuji; LeRoith Derek; Takeda Kiyoshi; Akira Shizuo; Kasuga Masato
Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo.
Nature medicine 2004;10(2):168-74.
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2004: Ozaki Michitaka; Irani Kaikobad
Measurement of in vivo oxidative stress regulated by the Rac1 GTPase.
Methods in enzymology 2004;381():184-91.
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2003: Haga Sanae; Terui Keita; Zhang Hui Qi; Enosawa Shin; Ogawa Wataru; Inoue Hiroshi; Okuyama Torayuki; Takeda Kiyoshi; Akira Shizuo; Ogino Tetsuya; Irani Kaikobad; Ozaki Michitaka
Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms.
The Journal of clinical investigation 2003;112(7):989-98.
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2003: Sakamoto Nobuaki; Sun Zhaoli; Brengman Matthew L; Maemura Korsei; Ozaki Michitaka; Bulkley Gregory B; Klein Andrew S
Hepatic reticuloendothelial system dysfunction after ischemia-reperfusion: role of P-selectin-mediated neutrophil accumulation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2003;9(9):940-8.
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2003: Ozaki M; Haga S; Zhang H Q; Irani K; Suzuki S
Inhibition of hypoxia/reoxygenation-induced oxidative stress in HGF-stimulated antiapoptotic signaling: role of PI3-K and Akt kinase upon rac1.
Cell death and differentiation 2003;10(5):508-15.
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2003: Jeon Byeong Hwa; Khanday Firdous; Deshpande Shailesh; Haile Azeb; Ozaki Michitaka; Irani Kaikobad
Tie-ing the antiinflammatory effect of angiopoietin-1 to inhibition of NF-kappaB.
Circulation research 2003;92(6):586-8.
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2003: Ozaki Michitaka; Enosawa Shin; Suzuki Seiichi
[Regenerative medicine in liver disease]
Nippon rinsho. Japanese journal of clinical medicine 2003;61(3):498-503.
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2002: Ozaki M; Haga S; Irani K; Amemiya H; Suzuki S
Overexpression of redox factor-1 protects against postischemic liver injury by reducing oxidative stress and NF-kappa B activity.
Transplantation proceedings 2002;34(7):2640-2.
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2002: Ozaki M
New strategy for preventing ischemia/reperfusion-induced organ injury and promoting regeneration: a novel trial for improving transplant organ function by targeted regulation of cellular signals.
Transplantation proceedings 2002;34(7):2637-9.
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2002: Kuroda T; Enosawa S; Endo M; Ozaki M; Morikawa N; Suzuki S; Amemiya H
Early infant kidneys as marginal donor sources: histology and pathophysiology.
Transplantation proceedings 2002;34(7):2582-4.
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2002: Endo Mitsufumi; Enosawa Shin; Ozaki Michitaka; Tsuruoka Shuichi; Hiramatsu Shinya; Kim Kazumi; Omasa Takeshi; Matsumura Toshiharu; Aoki Tatsuya; Koyanagi Yasuhisa; Suzuki Seiichi
Artificial mimicking of physiological active transport by a membrane co-cultured with two different cells: hepatic origin HepG2 and renal origin PCTL-MDR.
Artificial organs 2002;26(9):806-11.
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2002: Angkeow P; Deshpande S S; Qi B; Liu Y-X; Park Y C; Jeon B H; Ozaki M; Irani K
Redox factor-1: an extra-nuclear role in the regulation of endothelial oxidative stress and apoptosis.
Cell death and differentiation 2002;9(7):717-25.
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2002: Ozaki Michitaka; Suzuki Seiichi; Irani Kaikobad
Redox factor-1/APE suppresses oxidative stress by inhibiting the rac1 GTPase.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(8):889-90.
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2001: Ozaki M; Deshpande S; Angkeow P; Bellan J; Lowenstein C J; Dinauer M C; Goldschmidt-Clermont P; Suzuki S; Irani K
Targeted inhibition of the small GTPase protects against ischemia/reperfusion liver injury in mice.
Transplantation proceedings 2001;33(1-2):863-4.
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2000: Ozaki M; Deshpande S S; Angkeow P; Suzuki S; Irani K
Rac1 regulates stress-induced, redox-dependent heat shock factor activation.
The Journal of biological chemistry 2000;275(45):35377-83.
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2000: Paolocci N; Ekelund U E; Isoda T; Ozaki M; Vandegaer K; Georgakopoulos D; Harrison R W; Kass D A; Hare J M
cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation.
American journal of physiology. Heart and circulatory physiology 2000;279(4):H1982-8.
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2000: Deshpande S S; Angkeow P; Huang J; Ozaki M; Irani K
Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen species.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(12):1705-14.
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2000: Ozaki M; Deshpande S S; Angkeow P; Bellan J; Lowenstein C J; Dinauer M C; Goldschmidt-Clermont P J; Irani K
Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion-induced necrosis and apoptosis in vivo.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(2):418-29.
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1998: Tanaka K; Pracyk J B; Takeda K; Yu Z X; Ferrans V J; Deshpande S S; Ozaki M; Hwang P M; Lowenstein C J; Irani K; Finkel T
Expression of Id1 results in apoptosis of cardiac myocytes through a redox-dependent mechanism.
The Journal of biological chemistry 1998;273(40):25922-8.
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1997: Ozaki M; Nakamura M; Teraoka S; Ota K
Ebselen, a novel anti-oxidant compound, protects the rat liver from ischemia-reperfusion injury.
Transplant international : official journal of the European Society for Organ Transplantation 1997;10(2):96-102.
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1997: Nakamura M; Ozaki M; Fuchinoue S; Teraoka S; Ota K
Ascorbic acid prevents ischemia-reperfusion injury in the rat small intestine.
Transplant international : official journal of the European Society for Organ Transplantation 1997;10(2):89-95.
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1995: Ozaki M; Fuchinoue S; Teraoka S; Ota K
The in vivo cytoprotection of ascorbic acid against ischemia/reoxygenation injury of rat liver.
Archives of biochemistry and biophysics 1995;318(2):439-45.
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1994: Ozaki M; Ozasa H; Fuchinoue S; Teraoka S; Ota K
Protective effects of glycine and esterified gamma-glutamylcysteine on ischemia/reoxygenation injury of rat liver.
Transplantation 1994;58(6):753-5.
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1994: Ozaki M; Fuchinoue S; Teraoka S; Ota K
Mobilization of low-molecular-weight iron and peroxidative damage during ischemia and reoxygenation of the rat liver.
Transplantation proceedings 1994;26(2):918-21.
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1988: Ozaki M; Kawabata T; Awai M
Iron release from haemosiderin and production of iron-catalysed hydroxyl radicals in vitro.
The Biochemical journal 1988;250(2):589-95.
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1987: Sadahira Y; Mori M; Ozaki M; Awai M
Characteristics of histiocytic lesions in the reticuloendothelial system of NZB mice.
Acta pathologica japonica 1987;37(11):1719-29.
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