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Leila Aminova

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Disorders

Oxidative Stress

Physiology

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Hydroxylation

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Publications

TOP 3
Yuka Bannai; Melinda J Faulkner; M Ho; Leila Aminova; Brenda A Wilson
Rho/ROCK-dependent inhibition of 3T3-L1 adipogenesis by G-protein-deamidating dermonecrotic toxins: differential regulation of Notch1, Pref1/Dlk1, and β-catenin signaling.
Rajiv R Ratan; Ambreena Siddiq; Leila Aminova; Brett Langley; Stephen McConoughey; Ksenia Karpisheva; Hsin-Hwa Lee; Thomas Carmichael; Harley Kornblum; Giovanni Coppola; Daniel Geschwind; Ahmet Hoke; Natalya Smirnova; Cameron Rink; Sashwati Roy; Chandan K Sen; Michael S Beattie; Ron P Hart; Martin Grumet; Dongming Sun; Robert S Freeman; Gregg L Semenza; Irina Gazaryan
Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury.
Leila Aminova; Ambreena Siddiq; Rajiv R Ratan
Antioxidants, HIF prolyl hydroxylase inhibitors or short interfering RNAs to BNIP3 or PUMA, can prevent prodeath effects of the transcriptional activator, HIF-1alpha, in a mouse hippocampal neuronal line.

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All Publications

2012: Yuka Bannai; Melinda J Faulkner; M Ho; Leila Aminova; Brenda A Wilson
Rho/ROCK-dependent inhibition of 3T3-L1 adipogenesis by G-protein-deamidating dermonecrotic toxins: differential regulation of Notch1, Pref1/Dlk1, and β-catenin signaling.
Frontiers in cellular and infection microbiology 2012;2():80.
2008: Rajiv R Ratan; Ambreena Siddiq; Leila Aminova; Brett Langley; Stephen McConoughey; Ksenia Karpisheva; Hsin-Hwa Lee; Thomas Carmichael; Harley Kornblum; Giovanni Coppola; Daniel Geschwind; Ahmet Hoke; Natalya Smirnova; Cameron Rink; Sashwati Roy; Chandan K Sen; Michael S Beattie; Ron P Hart; Martin Grumet; Dongming Sun; Robert S Freeman; Gregg L Semenza; Irina Gazaryan
Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury.
Annals of the New York Academy of Sciences 2008;1147():383-94.
2008: Leila Aminova; Ambreena Siddiq; Rajiv R Ratan
Antioxidants, HIF prolyl hydroxylase inhibitors or short interfering RNAs to BNIP3 or PUMA, can prevent prodeath effects of the transcriptional activator, HIF-1alpha, in a mouse hippocampal neuronal line.
Antioxidants & redox signaling 2008;10(12):1989-98.
2008: Leila Aminova; Shuhong Luo; Yuka Bannai; M Ho; Brenda A Wilson
The C3 domain of Pasteurella multocida toxin is the minimal domain responsible for activation of Gq-dependent calcium and mitogenic signaling.
Protein science : a publication of the Protein Society 2008;17(5):945-9.
2008: Ambreena Siddiq; Leila Aminova; Rajiv R Ratan
Prolyl 4-hydroxylase activity-responsive transcription factors: from hydroxylation to gene expression and neuroprotection.
Frontiers in bioscience : a journal and virtual library 2008;13():2875-87.
2007: Leila Aminova; Brenda A Wilson
Calcineurin-independent inhibition of 3T3-L1 adipogenesis by Pasteurella multocida toxin: suppression of Notch1, stabilization of beta-catenin and pre-adipocyte factor 1.
Cellular microbiology 2007;9(10):2485-96.
2007: Ambreena Siddiq; Leila Aminova; Rajiv R Ratan
Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress.
Neurochemical research 2007;32(4-5):931-46.
2005: Ambreena Siddiq; Issam Ayoub; Juan C Chavez; Leila Aminova; Sapan Shah; Joseph C LaManna; Stephanie M Patton; James Connor; Robert A Cherny; Irene Volitakis; Ashley I Bush; Ingrid Langsetmo; Todd Seeley; Volkmar Gunzler; Rajiv R Ratan
Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system.
The Journal of biological chemistry 2005;280(50):41732-43.
2005: Junghee Lee; Chun-Hyung Kim; David K Simon; Leila Aminova; Alexander Andreyev; Yulia Kushnareva; Anne N Murphy; Bonnie E Lonze; Kwang-Soo Kim; David D Ginty; Robert J Ferrante; Hoon Ryu; Rajiv R Ratan
Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival.
The Journal of biological chemistry 2005;280(49):40398-401.
2005: Leila Aminova; Juan C Chavez; Junghee Lee; Hoon Ryu; Andrew L Kung; Joseph C Lamanna; Rajiv R Ratan
Prosurvival and prodeath effects of hypoxia-inducible factor-1alpha stabilization in a murine hippocampal cell line.
The Journal of biological chemistry 2005;280(5):3996-4003.
2004: Rajiv R Ratan; Ambreena Siddiq; Leila Aminova; Philipp S Lange; Brett Langley; Issam Ayoub; Joann M Gensert; Juan C Chavez
Translation of ischemic preconditioning to the patient: prolyl hydroxylase inhibition and hypoxia inducible factor-1 as novel targets for stroke therapy.
Stroke; a journal of cerebral circulation 2004;35(11 Suppl 1):2687-9.
2002: Katsuhiro Miura; Leila Aminova; Yuichi Murayama
Fusarenon-X induced apoptosis in HL-60 cells depends on caspase activation and cytochrome c release.
Toxicology 2002;172(2):103-12.
2000: Brenda A Wilson; Leila Aminova; VG Ponferrada; M Ho
Differential modulation and subsequent blockade of mitogenic signaling and cell cycle progression by Pasteurella multocida toxin.
Infection and immunity 2000;68(8):4531-8.
1991: Leila Aminova; E Kyslíková; O Volfová; Yuri A Trotsenko
Characterization of catalase-negative mutants of methylotrophic yeast Hansenula polymorpha.
Folia microbiologica 1991;36(2):158-63.
1988: L P Tikhomirova; R N Ikonomova; E N Kuznetsova; I I Fodor; L V Bystrykh; Leila Aminova
Transformation of methylotrophic yeast Hansenula polymorpha: cloning and expression of genes.
Journal of basic microbiology 1988;28(5):343-51.