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Francois Claret

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Xiao-Feng Le; Weiqun Mao; Zahid H Siddik; Weiya Xia; Ahmed Ashour Ahmed; Francois Claret; Guangan He; Mien-Chie Hung; Robert C Bast
The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.
Elias Drakos; Vasiliki Leventaki; Pei Lin; L Jeffrey Medeiros; Roberto N Miranda; Vasileios Atsaves; Francois Claret; Ellen Schlette; Francisco Vega; George Z Rassidakis
Expression of serine 194-phosphorylated Fas-associated death domain protein correlates with proliferation in B-cell non-Hodgkin lymphomas.
Elias Drakos; Rajesh R Singh; George Z Rassidakis; Ellen Schlette; J Li; Francois Claret; R J Ford; Francisco Vega; L Jeffrey Medeiros
Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21).

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All Publications

2011: Xiao-Feng Le; Weiqun Mao; Zahid H Siddik; Weiya Xia; Ahmed Ashour Ahmed; Francois Claret; Guangan He; Mien-Chie Hung; Robert C Bast
The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.
Journal of the National Cancer Institute 2011;103(18):1403-22.
2011: Elias Drakos; Vasiliki Leventaki; Pei Lin; L Jeffrey Medeiros; Roberto N Miranda; Vasileios Atsaves; Francois Claret; Ellen Schlette; Francisco Vega; George Z Rassidakis
Expression of serine 194-phosphorylated Fas-associated death domain protein correlates with proliferation in B-cell non-Hodgkin lymphomas.
Human pathology 2011;42(8):1117-24.
2011: Elias Drakos; Rajesh R Singh; George Z Rassidakis; Ellen Schlette; J Li; Francois Claret; R J Ford; Francisco Vega; L Jeffrey Medeiros
Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21).
Leukemia 2011;25(5):856-67.
2010: L Tian; G Peng; John M Parant; Vasiliki Leventaki; Elias Drakos; Qing Zhang; Jan Parker-Thornburg; T J Shackleford; H Dai; Shiaw-Yih Lin; Guillermina Lozano; George Z Rassidakis; Francois Claret
Essential roles of Jab1 in cell survival, spontaneous DNA damage and DNA repair.
Oncogene 2010;29(46):6125-37.
2010: Pablo Vivas-Mejia; Juliana Maria Benito; Ariel Fernandez; Hee-Dong Han; Lingegowda Mangala; Cristian Rodriguez-Aguayo; Arturo Chavez-Reyes; Yvonne G Lin; Mark S Carey; Alpa M Nick; Rebecca L Stone; Hye Sun Kim; Francois Claret; William G Bornmann; Bryan T. J. Hennessy; Angela M Sanguino; Zhengong Peng; Anil K Sood; Gabriel Lopez-Berestein
c-Jun-NH2-kinase-1 inhibition leads to antitumor activity in ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(1):184-94.
2009: Sonyo Shin; Takayuki Asano; Yixin Yao; Ronghua Zhang; Francois Claret; Murray Korc; Kanaga Sabapathy; David G Menter; James L Abbruzzese; Shrikanth A G Reddy
Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism.
Molecular cancer research : MCR 2009;7(5):745-54.
2007: Vasiliki Leventaki; Elias Drakos; L Jeffrey Medeiros; Megan S Lim; Kojo Seys John Elenitoba-Johnson; Francois Claret; George Z Rassidakis
NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell lymphoma.
Blood 2007;110(5):1621-30.
2007: Veronica C Estrella; Astrid Eder; Shuying Liu; Terri B Pustilnik; Fazal H Tabassam; Francois Claret; Gary E Gallick; Gordon B Mills; Jon R Wiener
Lysophosphatidic acid induction of urokinase plasminogen activator secretion requires activation of the p38MAPK pathway.
International journal of oncology 2007;31(2):441-9.
2006: Maria A Kouvaraki; Anita L Korapati; George Z Rassidakis; Ling Tian; Qingxiu Zhang; Paul J Chiao; Linus Ho; Douglas B Evans; Francois Claret
Potential role of Jun activation domain-binding protein 1 as a negative regulator of p27kip1 in pancreatic adenocarcinoma.
Cancer research 2006;66(17):8581-9.
2006: Francisco Vega; L Jeffrey Medeiros; Vasiliki Leventaki; Coralyn Atwell; Jeong Hee Cho-Vega; Ling Tian; Francois Claret; George Z Rassidakis
Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
Cancer research 2006;66(13):6589-97.
2006: Hyun-Jung Kim; Nitin Chakravarti; Nobuhiko Oridate; Chungyoul Choe; Francois Claret; Reuben Lotan
N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells.
Oncogene 2006;25(19):2785-94.
2005: George Z Rassidakis; Athanasios Thomaides; Coralyn Atwell; Richard Ford; Dan Jones; Francois Claret; L Jeffrey Medeiros
JunB expression is a common feature of CD30+ lymphomas and lymphomatoid papulosis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(10):1365-70.
2005: Qingxiu Zhang; Ling Tian; Abdellah Mansouri; Anita L Korapati; Terry J Johnson; Francois Claret
Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.
FEBS letters 2005;579(18):3932-40.
2005: George Z Rassidakis; Marianna Feretzaki; Coralyn Atwell; Ioannis Grammatikakis; Quan Lin; Raymond Lai; Francois Claret; L Jeffrey Medeiros; Hesham M Amin
Inhibition of Akt increases p27Kip1 levels and induces cell cycle arrest in anaplastic large cell lymphoma.
Blood 2005;105(2):827-9.
2004: Xianjun Fang; Shuangxing Yu; Robert C Bast; Shuying Liu; Hong-Ji Xu; Shi-Xue Hu; Ruth Lapushin; Francois Claret; Bharat B Aggarwal; Yiling Lu; Gordon B Mills
Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells.
The Journal of biological chemistry 2004;279(10):9653-61.
2003: Francisco J Esteva; Aysegul A Sahin; George Z Rassidakis; Linda X H Yuan; Terry L Smith; Ying Yang; Michael Z Gilcrease; Massimo Cristofanilli; Rita Nahta; Lajos Pusztai; Francois Claret
Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5652-9.
2003: Xiao-Feng Le; Francois Claret; Amy Lammayot; Ling Tian; Deepa Deshpande; Ruth Lapushin; Ana M Tari; Robert C Bast
The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition.
The Journal of biological chemistry 2003;278(26):23441-50.
2003: Maria A Kouvaraki; George Z Rassidakis; Ling Tian; Rakesh Kumar; Christos Kittas; Francois Claret
Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1).
Cancer research 2003;63(11):2977-81.
2003: Abdellah Mansouri; Lon D Ridgway; Anita L Korapati; Qingxiu Zhang; Ling Tian; Yibin Wang; Zahid H Siddik; Gordon B Mills; Francois Claret
Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells.
The Journal of biological chemistry 2003;278(21):19245-56.
2003: George Z Rassidakis; Francois Claret; Raymond Lai; Qingxiu Zhang; Andreas H Sarris; Timothy J McDonnell; L Jeffrey Medeiros
Expression of p27(Kip1) and c-Jun activation binding protein 1 are inversely correlated in systemic anaplastic large cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):1121-8.
2003: Abdellah Mansouri; Qingxiu Zhang; Lon D Ridgway; Ling Tian; Francois Claret
Cisplatin resistance in an ovarian carcinoma is associated with a defect in programmed cell death control through XIAP regulation.
Oncology research 2003;13(6-10):399-404.
2003: Megan Pyle; Marta Korbonits; Maria Gueorguiev; Suzanne Jordan; Blerina Kola; Damian G Morris; A Meinhardt; M P Powell; Francois Claret; Q Zhang; C Metz; R Bucala; Ashley B Grossman
Macrophage migration inhibitory factor expression is increased in pituitary adenoma cell nuclei.
The Journal of endocrinology 2003;176(1):103-10.
2002: Marta Korbonits; Harvinder S Chahal; Gregory A Kaltsas; Suzanne Jordan; Yulduz Urmanova; Zamira Khalimova; Philip E Harris; William E Farrell; Francois Claret; Ashley B Grossman
Expression of phosphorylated p27(Kip1) protein and Jun activation domain-binding protein 1 in human pituitary tumors.
The Journal of clinical endocrinology and metabolism 2002;87(6):2635-43.
2001: Ugur Aytac; Francois Claret; Linus Ho; Kazuya Sato; Kei Ohnuma; Gordon B Mills; Fernando Cabanillas; Chikao Morimoto; Nam H Dang
Expression of CD26 and its associated dipeptidyl peptidase IV enzyme activity enhances sensitivity to doxorubicin-induced cell cycle arrest at the G(2)/M checkpoint.
Cancer research 2001;61(19):7204-10.
2001: Lei Deng; Yen-Chiu Lin-Lee; Francois Claret; M Tien Kuo
2-acetylaminofluorene up-regulates rat mdr1b expression through generating reactive oxygen species that activate NF-kappa B pathway.
The Journal of biological chemistry 2001;276(1):413-20.
1999: Ho-Young Lee; N Sueoka; Waun Ki Hong; D J Mangelsdorf; Francois Claret; Jonathan M Kurie
All-trans-retinoic acid inhibits Jun N-terminal kinase by increasing dual-specificity phosphatase activity.
Molecular and cellular biology 1999;19(3):1973-80.
1999: Helen Le-Niculescu; E Bonfoco; Y Kasuya; Francois Claret; D R Green; Michael Karin
Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death.
Molecular and cellular biology 1999;19(1):751-63.
1998: Thomas Herdegen; Francois Claret; Tuula Kallunki; Ana Martin Villalba; Christine Winter; Tony Hunter; Michael Karin
Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(14):5124-35.
1997: Ho-Young Lee; Marcia I Dawson; Francois Claret; J D Chen; Garrett L Walsh; Waun Ki Hong; Jonathan M Kurie
Evidence of a retinoid signaling alteration involving the activator protein 1 complex in tumorigenic human bronchial epithelial cells and non-small cell lung cancer cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(3):283-91.
1996: Francois Claret; Masahiko Hibi; S Dhut; T Toda; Michael Karin
A new group of conserved coactivators that increase the specificity of AP-1 transcription factors.
Nature 1996;383(6599):453-7.
1996: Francois Claret; T Antakly; Michael Karin; F Saatcioglu
A shift in the ligand responsiveness of thyroid hormone receptor alpha induced by heterodimerization with retinoid X receptor alpha.
Molecular and cellular biology 1996;16(1):219-27.
1995: M Cavigelli; F Dolfi; Francois Claret; Michael Karin
Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.
The EMBO journal 1995;14(23):5957-64.
1995: Audrey Minden; A Lin; Francois Claret; Arie Abo; Michael Karin
Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs.
Cell 1995;81(7):1147-57.
1995: A Lin; Audrey Minden; H Martinetto; Francois Claret; C Lange-Carter; F Mercurio; Gary L Johnson; Michael Karin
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2.
Science (New York, N.Y.) 1995;268(5208):286-90.
1994: F Saatcioglu; Francois Claret; Michael Karin
Negative transcriptional regulation by nuclear receptors.
Seminars in cancer biology 1994;5(5):347-59.
1994: J Arias; ARTHUR S ALBERTS; Paul K Brindle; Francois Claret; T Smeal; Michael Karin; James R Feramisco; Marc Montminy
Activation of cAMP and mitogen responsive genes relies on a common nuclear factor.
Nature 1994;370(6486):226-9.
1994: Francois Claret; S Chapel; J Garcés; Monika Tsai-Pflugfelder; C Bertholet; David J Shapiro; Riccardo Wittek; Walter Wahli
Two functional forms of the Xenopus laevis estrogen receptor translated from a single mRNA species.
The Journal of biological chemistry 1994;269(19):14047-55.
1993: C Schild; Francois Claret; Walter Wahli; Alan P Wolffe
A nucleosome-dependent static loop potentiates estrogen-regulated transcription from the Xenopus vitellogenin B1 promoter in vitro.
The EMBO journal 1993;12(2):423-33.
1990: Blaise Corthésy; Francois Claret; Walter Wahli
Estrogen receptor level determines sex-specific in vitro transcription from the Xenopus vitellogenin promoter.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(20):7878-82.
1989: Blaise Corthésy; Jean-René Cardinaux; Francois Claret; Walter Wahli
A nuclear factor I-like activity and a liver-specific repressor govern estrogen-regulated in vitro transcription from the Xenopus laevis vitellogenin B1 promoter.
Molecular and cellular biology 1989;9(12):5548-62.
1988: B ten Heggler-Bordier; Francois Claret; Walter Wahli
Immuno-electron microscopic identification of human estrogen receptor-DNA complexes at the estrogen-responsive element and in the first intron of a Xenopus vitellogenin gene.
Journal of molecular biology 1988;204(1):217-20.