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Dennis Burton
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49
Parren, Paul
31
Williamson, Anthony
28
Wilson, Ian
27
Zwick, Michael
26
Barbas, Carlos
19
Pantophlet, Ralph
17
Poignard, Pascal
17
Binley, James
17
Ditzel, Henrik
15
Katinger, Hermann
14
Wang, Meng
13
Prusiner, Stanley
13
Dwek, Raymond
12
Stanfield, Robyn
12
Saphire, Erica Ollmann
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All Publications
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2009: Walker Laura M; Phogat Sanjay K; Chan-Hui Po-Ying; Wagner Denise; Phung Pham; Goss Julie L; Wrin Terri; Simek Melissa D; Fling Steven; Mitcham Jennifer L; Lehrman Jennifer K; Priddy Frances H; Olsen Ole A; Frey Steven M; Hammond Phillip W; Kaminsky Stephen; Zamb Timothy; Moyle Matthew; Koff Wayne C; Poignard Pascal; Burton Dennis R
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target.
Science (New York, N.Y.) 2009;326(5950):285-9.
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2009: Pejchal Robert; Gach Johannes S; Brunel Florence M; Cardoso Rosa M; Stanfield Robyn L; Dawson Philip E; Burton Dennis R; Zwick Michael B; Wilson Ian A
A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies.
Journal of virology 2009;83(17):8451-62.
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2009: Hessell Ann J; Poignard Pascal; Hunter Meredith; Hangartner Lars; Tehrani David M; Bleeker Wim K; Parren Paul W H I; Marx Preston A; Burton Dennis R
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques.
Nature medicine 2009;15(8):951-4.
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2009: Walker Laura M; Bowley Diana R; Burton Dennis R
Efficient recovery of high-affinity antibodies from a single-chain Fab yeast display library.
Journal of molecular biology 2009;389(2):365-75.
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2009: Hessell Ann J; Rakasz Eva G; Poignard Pascal; Hangartner Lars; Landucci Gary; Forthal Donald N; Koff Wayne C; Watkins David I; Burton Dennis R
Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers.
PLoS pathogens 2009;5(5):e1000433.
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2009: Wu Lan; Zhou Tongqing; Yang Zhi-yong; Svehla Krisha; O'Dell Sijy; Louder Mark K; Xu Ling; Mascola John R; Burton Dennis R; Hoxie James A; Doms Robert W; Kwong Peter D; Nabel Gary J
Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain.
Journal of virology 2009;83(10):5077-86.
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2009: Burton Dennis R; Poignard Pascal
HIV: Immune memory downloaded.
Nature 2009;458(7238):584-5.
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2009: Bowley Diana R; Jones Teresa M; Burton Dennis R; Lerner Richard A
Libraries against libraries for combinatorial selection of replicating antigen-antibody pairs.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(5):1380-5.
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2009: Pantophlet Ralph; Wang Meng; Aguilar-Sino Rowena O; Burton Dennis R
The human immunodeficiency virus type 1 envelope spike of primary viruses can suppress antibody access to variable regions.
Journal of virology 2009;83(4):1649-59.
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2008: Pantophlet Ralph; Wrin Terri; Cavacini Lisa A; Robinson James E; Burton Dennis R
Neutralizing activity of antibodies to the V3 loop region of HIV-1 gp120 relative to their epitope fine specificity.
Virology 2008;381(2):251-60.
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2008: Dunlop D Cameron; Ulrich Alexander; Appelmelk Ben J; Burton Dennis R; Dwek Raymond A; Zitzmann Nicole; Scanlan Christopher N
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
AIDS (London, England) 2008;22(16):2214-7.
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2008: Pollock Stephanie; Dwek Raymond A; Burton Dennis R; Zitzmann Nicole
N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery.
AIDS (London, England) 2008;22(15):1961-9.
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2008: Nicolaou K C; Wu T Robert; Sarlah David; Shaw David M; Rowcliffe Eric; Burton Dennis R
Total synthesis, revised structure, and biological evaluation of biyouyanagin A and analogues thereof.
Journal of the American Chemical Society 2008;130(33):11114-21.
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2008: Fauci Anthony S; Johnston Margaret I; Dieffenbach Carl W; Burton Dennis R; Hammer Scott M; Hoxie James A; Martin Malcolm; Overbaugh Julie; Watkins David I; Mahmoud Adel; Greene Warner C
HIV vaccine research: the way forward.
Science (New York, N.Y.) 2008;321(5888):530-2.
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2008: Lee Jeffrey E; Fusco Marnie L; Hessell Ann J; Oswald Wendelien B; Burton Dennis R; Saphire Erica Ollmann
Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor.
Nature 2008;454(7201):177-82.
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2008: Nelson Josh D; Kinkead Heather; Brunel Florence M; Leaman Dan; Jensen Richard; Louis John M; Maruyama Toshiaki; Bewley Carole A; Bowdish Katherine; Clore G Marius; Dawson Philip E; Frederickson Shana; Mage Rose G; Richman Douglas D; Burton Dennis R; Zwick Michael B
Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics.
Virology 2008;377(1):170-83.
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2008: Astronomo Rena D; Lee Hing-Ken; Scanlan Christopher N; Pantophlet Ralph; Huang Cheng-Yuan; Wilson Ian A; Blixt Ola; Dwek Raymond A; Wong Chi-Huey; Burton Dennis R
A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
Journal of virology 2008;82(13):6359-68.
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2008: Menendez Alfredo; Calarese Daniel A; Stanfield Robyn L; Chow Keith C; Scanlan Chris N; Kunert Renate; Katinger Herman; Burton Dennis R; Wilson Ian A; Scott Jamie K
A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(5):1380-92.
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2008: Scanlan Christopher N; Burton Dennis R; Dwek Raymond A
Making autoantibodies safe.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4081-2.
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2008: Wang Sheng-Kai; Liang Pi-Hui; Astronomo Rena D; Hsu Tsui-Ling; Hsieh Shie-Liang; Burton Dennis R; Wong Chi-Huey
Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3690-5.
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2008: Selvarajah Suganya; Puffer Bridget A; Lee Fang-Hua; Zhu Ping; Li Yuxing; Wyatt Richard; Roux Kenneth H; Doms Robert W; Burton Dennis R
Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140.
AIDS research and human retroviruses 2008;24(2):301-14.
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2008: Karlsson Hedestam Gunilla B; Fouchier Ron A M; Phogat Sanjay; Burton Dennis R; Sodroski Joseph; Wyatt Richard T
The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.
Nature reviews. Microbiology 2008;6(2):143-55.
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2008: Bell Christian H; Pantophlet Ralph; Schiefner André; Cavacini Lisa A; Stanfield Robyn L; Burton Dennis R; Wilson Ian A
Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization.
Journal of molecular biology 2008;375(4):969-78.
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2008: Law Mansun; Maruyama Toshiaki; Lewis Jamie; Giang Erick; Tarr Alexander W; Stamataki Zania; Gastaminza Pablo; Chisari Francis V; Jones Ian M; Fox Robert I; Ball Jonathan K; McKeating Jane A; Kneteman Norman M; Burton Dennis R
Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge.
Nature medicine 2008;14(1):25-7.
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2007: Zwick Michael B; Burton Dennis R
HIV-1 neutralization: mechanisms and relevance to vaccine design.
Current HIV research 2007;5(6):608-24.
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2007: Scherer Erin M; Zwick Michael B; Teyton Luc; Burton Dennis R
Difficulties in eliciting broadly neutralizing anti-HIV antibodies are not explained by cardiolipin autoreactivity.
AIDS (London, England) 2007;21(16):2131-9.
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2007: Burton Dennis R; Wilson Ian A
Immunology. Square-dancing antibodies.
Science (New York, N.Y.) 2007;317(5844):1507-8.
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2007: Hessell Ann J; Hangartner Lars; Hunter Meredith; Havenith Carin E G; Beurskens Frank J; Bakker Joost M; Lanigan Caroline M S; Landucci Gary; Forthal Donald N; Parren Paul W H I; Marx Preston A; Burton Dennis R
Fc receptor but not complement binding is important in antibody protection against HIV.
Nature 2007;449(7158):101-4.
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2007: Mantis Nicholas J; Palaia Jana; Hessell Ann J; Mehta Simren; Zhu Zhiyi; Corthésy Blaise; Neutra Marian R; Burton Dennis R; Janoff Edward N
Inhibition of HIV-1 infectivity and epithelial cell transfer by human monoclonal IgG and IgA antibodies carrying the b12 V region.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(5):3144-52.
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2007: Scanlan Christopher N; Ritchie Gayle E; Baruah Kavitha; Crispin Max; Harvey David J; Singer Bernhard B; Lucka Lothar; Wormald Mark R; Wentworth Paul; Zitzmann Nicole; Rudd Pauline M; Burton Dennis R; Dwek Raymond A
Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody.
Journal of molecular biology 2007;372(1):16-22.
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2007: Crooks Emma T; Moore Penny L; Franti Michael; Cayanan Charmagne S; Zhu Ping; Jiang Pengfei; de Vries Robbert P; Wiley Cheryl; Zharkikh Irina; Schülke Norbert; Roux Kenneth H; Montefiori David C; Burton Dennis R; Binley James M
A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.
Virology 2007;366(2):245-62.
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2007: Williams John V; Chen Zhifeng; Cseke Gabriella; Wright David W; Keefer Christopher J; Tollefson Sharon J; Hessell Ann; Podsiad Amy; Shepherd Bryan E; Sanna Pietro Paolo; Burton Dennis R; Crowe James E; Williamson R Anthony
A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo.
Journal of virology 2007;81(15):8315-24.
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2007: Pantophlet Ralph; Aguilar-Sino Rowena O; Wrin Terri; Cavacini Lisa A; Burton Dennis R
Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis.
Virology 2007;364(2):441-53.
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2007: Saphire Erica Ollmann; Montero Marinieve; Menendez Alfredo; van Houten Nienke E; Irving Melita B; Pantophlet Ralph; Zwick Michael B; Parren Paul W H I; Burton Dennis R; Scott Jamie K; Wilson Ian A
Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies.
Journal of molecular biology 2007;369(3):696-709.
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2007: Dhillon Amandeep K; Donners Helen; Pantophlet Ralph; Johnson Welkin E; Decker Julie M; Shaw George M; Lee Fang-Hua; Richman Douglas D; Doms Robert W; Vanham Guido; Burton Dennis R
Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors.
Journal of virology 2007;81(12):6548-62.
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2007: Nelson Josh D; Brunel Florence M; Jensen Richard; Crooks Emma T; Cardoso Rosa M F; Wang Meng; Hessell Ann; Wilson Ian A; Binley James M; Dawson Philip E; Burton Dennis R; Zwick Michael B
An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10.
Journal of virology 2007;81(8):4033-43.
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2007: Law Mansun; Cardoso Rosa M F; Wilson Ian A; Burton Dennis R
Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy.
Journal of virology 2007;81(8):4272-85.
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2007: Zhou Tongqing; Xu Ling; Dey Barna; Hessell Ann J; Van Ryk Donald; Xiang Shi-Hua; Yang Xinzhen; Zhang Mei-Yun; Zwick Michael B; Arthos James; Burton Dennis R; Dimitrov Dimiter S; Sodroski Joseph; Wyatt Richard; Nabel Gary J; Kwong Peter D
Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature 2007;445(7129):732-7.
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2007: Bowley D R; Labrijn A F; Zwick M B; Burton D R
Antigen selection from an HIV-1 immune antibody library displayed on yeast yields many novel antibodies compared to selection from the same library displayed on phage.
Protein engineering, design & selection : PEDS 2007;20(2):81-90.
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2007: Cardoso Rosa M F; Brunel Florence M; Ferguson Sharon; Zwick Michael; Burton Dennis R; Dawson Philip E; Wilson Ian A
Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
Journal of molecular biology 2007;365(5):1533-44.
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2007: Oswald Wendelien B; Geisbert Thomas W; Davis Kelly J; Geisbert Joan B; Sullivan Nancy J; Jahrling Peter B; Parren Paul W H I; Burton Dennis R
Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys.
PLoS pathogens 2007;3(1):e9.
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2006: Leclerc E; Serban H; Prusiner S B; Burton D R; Williamson R A
Copper induces conformational changes in the N-terminal part of cell-surface PrPC.
Archives of virology 2006;151(11):2103-9.
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2006: Luginbühl Béatrice; Kanyo Zoltan; Jones R Mark; Fletterick Robert J; Prusiner Stanley B; Cohen Fred E; Williamson R Anthony; Burton Dennis R; Plückthun Andreas
Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation.
Journal of molecular biology 2006;363(1):75-97.
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2006: Burton Dennis R; Dwek Raymond A
Immunology. Sugar determines antibody activity.
Science (New York, N.Y.) 2006;313(5787):627-8.
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2006: Yuste Eloisa; Sanford Hannah B; Carmody Jill; Bixby Jacqueline; Little Susan; Zwick Michael B; Greenough Tom; Burton Dennis R; Richman Douglas D; Desrosiers Ronald C; Johnson Welkin E
Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma.
Journal of virology 2006;80(6):3030-41.
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2006: Moore Penny L; Crooks Emma T; Porter Lauren; Zhu Ping; Cayanan Charmagne S; Grise Henry; Corcoran Paul; Zwick Michael B; Franti Michael; Morris Lynn; Roux Kenneth H; Burton Dennis R; Binley James M
Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.
Journal of virology 2006;80(5):2515-28.
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2006: Brunel Florence M; Zwick Michael B; Cardoso Rosa M F; Nelson Josh D; Wilson Ian A; Burton Dennis R; Dawson Philip E
Structure-function analysis of the epitope for 4E10, a broadly neutralizing human immunodeficiency virus type 1 antibody.
Journal of virology 2006;80(4):1680-7.
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2006: Venturini Sara; Allicotti Gina; Zhao Yindong; Simon Richard; Burton Dennis R; Pinilla Clemencia; Poignard Pascal
Identification of peptides from human pathogens able to cross-activate an HIV-1-gag-specific CD4+ T cell clone.
European journal of immunology 2006;36(1):27-36.
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2006: Binley James M; Ngo-Abdalla Stacie; Moore Penny; Bobardt Michael; Chatterji Udayan; Gallay Philippe; Burton Dennis R; Wilson Ian A; Elder John H; de Parseval Aymeric
Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120.
Retrovirology 2006;3():39.
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2006: Pantophlet Ralph; Burton Dennis R
GP120: target for neutralizing HIV-1 antibodies.
Annual review of immunology 2006;24():739-69.
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2005: Burton Dennis R; Stanfield Robyn L; Wilson Ian A
Antibody vs. HIV in a clash of evolutionary titans.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(42):14943-8.
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2005: Selvarajah Suganya; Puffer Bridget; Pantophlet Ralph; Law Mansun; Doms Robert W; Burton Dennis R
Comparing antigenicity and immunogenicity of engineered gp120.
Journal of virology 2005;79(19):12148-63.
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2005: Calarese Daniel A; Lee Hing-Ken; Huang Cheng-Yuan; Best Michael D; Astronomo Rena D; Stanfield Robyn L; Katinger Hermann; Burton Dennis R; Wong Chi-Huey; Wilson Ian A
Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13372-7.
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2005: Lindenbach Brett D; Evans Matthew J; Syder Andrew J; Wölk Benno; Tellinghuisen Timothy L; Liu Christopher C; Maruyama Toshiaki; Hynes Richard O; Burton Dennis R; McKeating Jane A; Rice Charles M
Complete replication of hepatitis C virus in cell culture.
Science (New York, N.Y.) 2005;309(5734):623-6.
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2005: Zhong Jin; Gastaminza Pablo; Cheng Guofeng; Kapadia Sharookh; Kato Takanobu; Burton Dennis R; Wieland Stefan F; Uprichard Susan L; Wakita Takaji; Chisari Francis V
Robust hepatitis C virus infection in vitro.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9294-9.
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2005: Koefoed Klaus; Farnaes Lauge; Wang Meng; Svejgaard Arne; Burton Dennis R; Ditzel Henrik J
Molecular characterization of the circulating anti-HIV-1 gp120-specific B cell repertoire using antibody phage display libraries generated from pre-selected HIV-1 gp120 binding PBLs.
Journal of immunological methods 2005;297(1-2):187-201.
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2005: Cardoso Rosa M F; Zwick Michael B; Stanfield Robyn L; Kunert Renate; Binley James M; Katinger Hermann; Burton Dennis R; Wilson Ian A
Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41.
Immunity 2005;22(2):163-73.
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2005: Zwick Michael B; Jensen Richard; Church Sarah; Wang Meng; Stiegler Gabriela; Kunert Renate; Katinger Hermann; Burton Dennis R
Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1.
Journal of virology 2005;79(2):1252-61.
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2004: Blixt Ola; Head Steve; Mondala Tony; Scanlan Christopher; Huflejt Margaret E; Alvarez Richard; Bryan Marian C; Fazio Fabio; Calarese Daniel; Stevens James; Razi Nahid; Stevens David J; Skehel John J; van Die Irma; Burton Dennis R; Wilson Ian A; Cummings Richard; Bovin Nicolai; Wong Chi-Huey; Paulson James C
Printed covalent glycan array for ligand profiling of diverse glycan binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17033-8.
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2004: Binley James M; Wrin Terri; Korber Bette; Zwick Michael B; Wang Meng; Chappey Colombe; Stiegler Gabriela; Kunert Renate; Zolla-Pazner Susan; Katinger Hermann; Petropoulos Christos J; Burton Dennis R
Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies.
Journal of virology 2004;78(23):13232-52.
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2004: Pantophlet R; Wilson I A; Burton D R
Improved design of an antigen with enhanced specificity for the broadly HIV-neutralizing antibody b12.
Protein engineering, design & selection : PEDS 2004;17(10):749-58.
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2004: Zhang Mei-Yun; Xiao Xiaodong; Sidorov Igor A; Choudhry Vidita; Cham Fatim; Zhang Peng Fei; Bouma Peter; Zwick Michael; Choudhary Anil; Montefiori David C; Broder Christopher C; Burton Dennis R; Quinnan Gerald V; Dimitrov Dimiter S
Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody.
Journal of virology 2004;78(17):9233-42.
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2004: Moore John P; Burton Dennis R
Urgently needed: a filter for the HIV-1 vaccine pipeline.
Nature medicine 2004;10(8):769-71.
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2004: Moroncini Gianluca; Kanu Nnennaya; Solforosi Laura; Abalos Gil; Telling Glenn C; Head Mark; Ironside James; Brockes Jeremy P; Burton Dennis R; Williamson R Anthony
Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(28):10404-9.
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2004: Maruyama Toshiaki; Saito Ichiro; Hayashi Yoshio; Kompfner Elizabeth; Fox Robert I; Burton Dennis R; Ditzel Henrik J
Molecular analysis of the human autoantibody response to alpha-fodrin in Sjögren's syndrome reveals novel apoptosis-induced specificity.
The American journal of pathology 2004;165(1):53-61.
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2004: Zwick Michael B; Komori H Kiyomi; Stanfield Robyn L; Church Sarah; Wang Meng; Parren Paul W H I; Kunert Renate; Katinger Hermann; Wilson Ian A; Burton Dennis R
The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5.
Journal of virology 2004;78(6):3155-61.
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2004: Burton Dennis R; Desrosiers Ronald C; Doms Robert W; Koff Wayne C; Kwong Peter D; Moore John P; Nabel Gary J; Sodroski Joseph; Wilson Ian A; Wyatt Richard T
HIV vaccine design and the neutralizing antibody problem.
Nature immunology 2004;5(3):233-6.
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2004: Biorn Alyssa C; Cocklin Simon; Madani Navid; Si Zhihai; Ivanovic Tijana; Samanen James; Van Ryk Donald I; Pantophlet Ralph; Burton Dennis R; Freire Ernesto; Sodroski Joseph; Chaiken Irwin M
Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions.
Biochemistry 2004;43(7):1928-38.
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2004: Lee Hing-Ken; Scanlan Christopher N; Huang Cheng-Yuan; Chang Aileen Y; Calarese Daniel A; Dwek Raymond A; Rudd Pauline M; Burton Dennis R; Wilson Ian A; Wong Chi-Huey
Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody.
Angewandte Chemie (International ed. in English) 2004;43(8):1000-3.
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2004: Darbha Ramalakshmi; Phogat Sanjay; Labrijn Aran F; Shu Yuuei; Gu Yijun; Andrykovitch Michelle; Zhang Mei-Yun; Pantophlet Ralph; Martin Loic; Vita Claudio; Burton Dennis R; Dimitrov Dimiter S; Ji Xinhua
Crystal structure of the broadly cross-reactive HIV-1-neutralizing Fab X5 and fine mapping of its epitope.
Biochemistry 2004;43(6):1410-7.
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2004: Zwick Michael B; Saphire Erica O; Burton Dennis R
gp41: HIV's shy protein.
Nature medicine 2004;10(2):133-4.
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2003: Pantophlet Ralph; Burton Dennis R
Immunofocusing: antigen engineering to promote the induction of HIV-neutralizing antibodies.
Trends in molecular medicine 2003;9(11):468-73.
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2003: Labrijn Aran F; Poignard Pascal; Raja Aarti; Zwick Michael B; Delgado Karla; Franti Michael; Binley James; Vivona Veronique; Grundner Christoph; Huang Chih-Chin; Venturi Miro; Petropoulos Christos J; Wrin Terri; Dimitrov Dimiter S; Robinson James; Kwong Peter D; Wyatt Richard T; Sodroski Joseph; Burton Dennis R
Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1.
Journal of virology 2003;77(19):10557-65.
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2003: Mascola John R; Lewis Mark G; VanCott Thomas C; Stiegler Gabriela; Katinger Hermann; Seaman Michael; Beaudry Kristin; Barouch Dan H; Korioth-Schmitz Birgit; Krivulka Georgia; Sambor Anna; Welcher Brent; Douek Daniel C; Montefiori David C; Shiver John W; Poignard Pascal; Burton Dennis R; Letvin Norman L
Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies.
Journal of virology 2003;77(19):10348-56.
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2003: Johnson Welkin E; Sanford Hannah; Schwall Linda; Burton Dennis R; Parren Paul W H I; Robinson James E; Desrosiers Ronald C
Assorted mutations in the envelope gene of simian immunodeficiency virus lead to loss of neutralization resistance against antibodies representing a broad spectrum of specificities.
Journal of virology 2003;77(18):9993-10003.
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2003: Peters Peter J; Mironov Alexander; Peretz David; van Donselaar Elly; Leclerc Estelle; Erpel Susanne; DeArmond Stephen J; Burton Dennis R; Williamson R Anthony; Vey Martin; Prusiner Stanley B
Trafficking of prion proteins through a caveolae-mediated endosomal pathway.
The Journal of cell biology 2003;162(4):703-17.
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2003: Choe Hyeryun; Li Wenhui; Wright Paulette L; Vasilieva Natalya; Venturi Miro; Huang Chih-Chin; Grundner Christoph; Dorfman Tatyana; Zwick Michael B; Wang Liping; Rosenberg Eric S; Kwong Peter D; Burton Dennis R; Robinson James E; Sodroski Joseph G; Farzan Michael
Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120.
Cell 2003;114(2):161-70.
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2003: Calarese Daniel A; Scanlan Christopher N; Zwick Michael B; Deechongkit Songpon; Mimura Yusuke; Kunert Renate; Zhu Ping; Wormald Mark R; Stanfield Robyn L; Roux Kenneth H; Kelly Jeffery W; Rudd Pauline M; Dwek Raymond A; Katinger Hermann; Burton Dennis R; Wilson Ian A
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Science (New York, N.Y.) 2003;300(5628):2065-71.
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2003: Zwick Michael B; Kelleher Robert; Jensen Richard; Labrijn Aran F; Wang Meng; Quinnan Gerald V; Parren Paul W H I; Burton Dennis R
A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12.
Journal of virology 2003;77(12):6965-78.
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2003: Pantophlet Ralph; Wilson Ian A; Burton Dennis R
Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine design.
Journal of virology 2003;77(10):5889-901.
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2003: Zwick Michael B; Parren Paul W H I; Saphire Erica O; Church Sarah; Wang Meng; Scott Jamie K; Dawson Philip E; Wilson Ian A; Burton Dennis R
Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120.
Journal of virology 2003;77(10):5863-76.
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2003: Binley James M; Cayanan Charmagne S; Wiley Cheryl; Schülke Norbert; Olson William C; Burton Dennis R
Redox-triggered infection by disulfide-shackled human immunodeficiency virus type 1 pseudovirions.
Journal of virology 2003;77(10):5678-84.
-
2003: Leclerc Estelle; Peretz David; Ball Haydn; Solforosi Laura; Legname Giuseppe; Safar Jiri; Serban Ana; Prusiner Stanley B; Burton Dennis R; Williamson R Anthony
Conformation of PrP(C) on the cell surface as probed by antibodies.
Journal of molecular biology 2003;326(2):475-83.
-
2003: Herrera Carolina; Spenlehauer Catherine; Fung Michael S; Burton Dennis R; Beddows Simon; Moore John P
Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site.
Journal of virology 2003;77(2):1084-91.
-
2003: Pantophlet Ralph; Ollmann Saphire Erica; Poignard Pascal; Parren Paul W H I; Wilson Ian A; Burton Dennis R
Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.
Journal of virology 2003;77(1):642-58.
-
2003: Poignard Pascal; Moulard Maxime; Golez Edwin; Vivona Veronique; Franti Michael; Venturini Sara; Wang Meng; Parren Paul W H I; Burton Dennis R
Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies.
Journal of virology 2003;77(1):353-65.
-
2003: Scanlan Christopher N; Pantophlet Ralph; Wormald Mark R; Saphire Erica Ollmann; Calarese Daniel; Stanfield Robyn; Wilson Ian A; Katinger Hermann; Dwek Raymond A; Burton Dennis R; Rudd Pauline M
The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12.
Advances in experimental medicine and biology 2003;535():205-18.
-
2003: Saphire Erica Ollmann; Stanfield Robyn L; Crispin M D Max; Morris Garrett; Zwick Michael B; Pantophlet Ralph A; Parren Paul W H I; Rudd Pauline M; Dwek Raymond A; Burton Dennis R; Wilson Ian A
Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design.
Advances in experimental medicine and biology 2003;535():55-66.
-
2002: Kwong Peter D; Doyle Michael L; Casper David J; Cicala Claudia; Leavitt Stephanie A; Majeed Shahzad; Steenbeke Tavis D; Venturi Miro; Chaiken Irwin; Fung Michael; Katinger Hermann; Parren Paul W I H; Robinson James; Van Ryk Donald; Wang Liping; Burton Dennis R; Freire Ernesto; Wyatt Richard; Sodroski Joseph; Hendrickson Wayne A; Arthos James
HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites.
Nature 2002;420(6916):678-82.
-
2002: Safar Jiri G; Scott Michael; Monaghan Jeff; Deering Camille; Didorenko Svetlana; Vergara Julie; Ball Haydn; Legname Giuseppe; Leclerc Estelle; Solforosi Laura; Serban Hana; Groth Darlene; Burton Dennis R; Prusiner Stanley B; Williamson R Anthony
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice.
Nature biotechnology 2002;20(11):1147-50.
-
2002: Meissner Felix; Maruyama Toshiaki; Frentsch Marco; Hessell Ann J; Rodriguez Luis L; Geisbert Tom W; Jahrling Peter B; Burton Dennis R; Parren Paul W H I
Detection of antibodies against the four subtypes of ebola virus in sera from any species using a novel antibody-phage indicator assay.
Virology 2002;300(2):236-43.
-
2002: Burton Dennis R
Antibodies, viruses and vaccines.
Nature reviews. Immunology 2002;2(9):706-13.
-
2002: Scanlan Christopher N; Pantophlet Ralph; Wormald Mark R; Ollmann Saphire Erica; Stanfield Robyn; Wilson Ian A; Katinger Hermann; Dwek Raymond A; Rudd Pauline M; Burton Dennis R
The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.
Journal of virology 2002;76(14):7306-21.
-
2002: Venturini Sara; Mosier Donald E; Burton Dennis R; Poignard Pascal
Characterization of human immunodeficiency virus type 1 (HIV-1) Gag- and Gag peptide-specific CD4(+) T-cell clones from an HIV-1-seronegative donor following in vitro immunization.
Journal of virology 2002;76(14):6987-99.
-
2002: Peretz David; Williamson R Anthony; Legname Giuseppe; Matsunaga Yoichi; Vergara Julie; Burton Dennis R; DeArmond Stephen J; Prusiner Stanley B; Scott Michael R
A change in the conformation of prions accompanies the emergence of a new prion strain.
Neuron 2002;34(6):921-32.
-
2002: Parren Paul W H I; Geisbert Tom W; Maruyama Toshiaki; Jahrling Peter B; Burton Dennis R
Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody.
Journal of virology 2002;76(12):6408-12.
-
2002: Saphire Erica Ollmann; Stanfield Robyn L; Crispin M D Max; Parren Paul W H I; Rudd Pauline M; Dwek Raymond A; Burton Dennis R; Wilson Ian A
Contrasting IgG structures reveal extreme asymmetry and flexibility.
Journal of molecular biology 2002;319(1):9-18.
-
2002: Moulard Maxime; Phogat Sanjay K; Shu Yuuei; Labrijn Aran F; Xiao Xiaodong; Binley James M; Zhang Mei-Yun; Sidorov Igor A; Broder Christopher C; Robinson James; Parren Paul W H I; Burton Dennis R; Dimitrov Dimiter S
Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6913-8.
-
2002: Binley James M; Sanders Rogier W; Master Aditi; Cayanan Charmagne S; Wiley Cheryl L; Schiffner Linnea; Travis Bruce; Kuhmann Shawn; Burton Dennis R; Hu Shiu-Lok; Olson William C; Moore John P
Enhancing the proteolytic maturation of human immunodeficiency virus type 1 envelope glycoproteins.
Journal of virology 2002;76(6):2606-16.
-
2001: Zwick M B; Wang M; Poignard P; Stiegler G; Katinger H; Burton D R; Parren P W
Neutralization synergy of human immunodeficiency virus type 1 primary isolates by cocktails of broadly neutralizing antibodies.
Journal of virology 2001;75(24):12198-208.
-
2001: Zwick M B; Labrijn A F; Wang M; Spenlehauer C; Saphire E O; Binley J M; Moore J P; Stiegler G; Katinger H; Burton D R; Parren P W
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.
Journal of virology 2001;75(22):10892-905.
-
2001: Parren P W; Marx P A; Hessell A J; Luckay A; Harouse J; Cheng-Mayer C; Moore J P; Burton D R
Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro.
Journal of virology 2001;75(17):8340-7.
-
2001: Peretz D; Williamson R A; Kaneko K; Vergara J; Leclerc E; Schmitt-Ulms G; Mehlhorn I R; Legname G; Wormald M R; Rudd P M; Dwek R A; Burton D R; Prusiner S B
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity.
Nature 2001;412(6848):739-43.
-
2001: Saphire E O; Parren P W; Pantophlet R; Zwick M B; Morris G M; Rudd P M; Dwek R A; Stanfield R L; Burton D R; Wilson I A
Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.
Science (New York, N.Y.) 2001;293(5532):1155-9.
-
2001: Schaller M; Burton D R; Ditzel H J
Autoantibodies to GPI in rheumatoid arthritis: linkage between an animal model and human disease.
Nature immunology 2001;2(8):746-53.
-
2001: Zwick M B; Bonnycastle L L; Menendez A; Irving M B; Barbas C F; Parren P W; Burton D R; Scott J K
Identification and characterization of a peptide that specifically binds the human, broadly neutralizing anti-human immunodeficiency virus type 1 antibody b12.
Journal of virology 2001;75(14):6692-9.
-
2001: Moore J P; Parren P W; Burton D R
Genetic subtypes, humoral immunity, and human immunodeficiency virus type 1 vaccine development.
Journal of virology 2001;75(13):5721-9.
-
2001: Leclerc E; Peretz D; Ball H; Sakurai H; Legname G; Serban A; Prusiner S B; Burton D R; Williamson R A
Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form.
The EMBO journal 2001;20(7):1547-54.
-
2001: Peretz D; Scott M R; Groth D; Williamson R A; Burton D R; Cohen F E; Prusiner S B
Strain-specified relative conformational stability of the scrapie prion protein.
Protein science : a publication of the Protein Society 2001;10(4):854-63.
-
2001: Williamson R A; Burgoon M P; Owens G P; Ghausi O; Leclerc E; Firme L; Carlson S; Corboy J; Parren P W; Sanna P P; Gilden D H; Burton D R
Anti-DNA antibodies are a major component of the intrathecal B cell response in multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1793-8.
-
2001: Gilden D H; Burgoon M P; Kleinschmidt-DeMasters B K; Williamson R A; Ghausi O; Burton D R; Owens G P
Molecular immunologic strategies to identify antigens and b-cell responses unique to multiple sclerosis.
Archives of neurology 2001;58(1):43-8.
-
2001: Saphire E O; Parren P W; Barbas C F; Burton D R; Wilson I A
Crystallization and preliminary structure determination of an intact human immunoglobulin, b12: an antibody that broadly neutralizes primary isolates of HIV-1.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 1):168-71.
-
2001: Burton D R; Saphire E O; Parren P W
A model for neutralization of viruses based on antibody coating of the virion surface.
Current topics in microbiology and immunology 2001;260():109-43.
-
2001: Parren P W; Burton D R
The antiviral activity of antibodies in vitro and in vivo.
Advances in immunology 2001;77():195-262.
-
2001: Poignard P; Saphire E O; Parren P W; Burton D R
gp120: Biologic aspects of structural features.
Annual review of immunology 2001;19():253-74.
-
2000: Sanna P P; Burton D R
Role of antibodies in controlling viral disease: lessons from experiments of nature and gene knockouts.
Journal of virology 2000;74(21):9813-7.
-
2000: Ditzel H J; Masaki Y; Nielsen H; Farnaes L; Burton D R
Cloning and expression of a novel human antibody-antigen pair associated with Felty's syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):9234-9.
-
2000: Dorrell L; Hessell A J; Wang M; Whittle H; Sabally S; Rowland-Jones S; Burton D R; Parren P W
Absence of specific mucosal antibody responses in HIV-exposed uninfected sex workers from the Gambia.
AIDS (London, England) 2000;14(9):1117-22.
-
2000: Burton D R; Williamson R A; Parren P W
Antibody and virus: binding and neutralization.
Virology 2000;270(1):1-3.
-
2000: Burton D R; Parren P W
Vaccines and the induction of functional antibodies: time to look beyond the molecules of natural infection?
Nature medicine 2000;6(2):123-5.
-
2000: Owens G P; Williamson R A; Burgoon M P; Ghausi O; Burton D R; Gilden D H
Cloning the antibody response in humans with chronic inflammatory disease: immunopanning of subacute sclerosing panencephalitis (SSPE) brain sections with antibody phage libraries prepared from SSPE brain enriches for antibody recognizing measles virus antigens in situ.
Journal of virology 2000;74(3):1533-7.
-
2000: Wang H; Griffiths M N; Burton D R; Ghazal P
Rapid antibody responses by low-dose, single-step, dendritic cell-targeted immunization.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):847-52.
-
2000: Parren P W; Poignard P; Ditzel H J; Williamson R A; Burton D R
Antibodies in human infectious disease.
Immunologic research 2000;21(2-3):265-78.
-
1999: Kanyo Z F; Pan K M; Williamson R A; Burton D R; Prusiner S B; Fletterick R J; Cohen F E
Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
Journal of molecular biology 1999;293(4):855-63.
-
1999: Maruyama T; Rodriguez L L; Jahrling P B; Sanchez A; Khan A S; Nichol S T; Peters C J; Parren P W; Burton D R
Ebola virus can be effectively neutralized by antibody produced in natural human infection.
Journal of virology 1999;73(7):6024-30.
-
1999: Poignard P; Sabbe R; Picchio G R; Wang M; Gulizia R J; Katinger H; Parren P W; Mosier D E; Burton D R
Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo.
Immunity 1999;10(4):431-8.
-
1999: Sakurai H; Williamson R A; Crowe J E; Beeler J A; Poignard P; Bastidas R B; Chanock R M; Burton D R
Human antibody responses to mature and immature forms of viral envelope in respiratory syncytial virus infection: significance for subunit vaccines.
Journal of virology 1999;73(4):2956-62.
-
1999: Sanna P P; Samson M E; Moon J S; Rozenshteyn R; De Logu A; Williamson R A; Burton D R
pFab-CMV, a single vector system for the rapid conversion of recombinant Fabs into whole IgG1 antibodies.
Immunotechnology : an international journal of immunological engineering 1999;4(3-4):185-8.
-
1999: Burgoon M P; Williamson R A; Owens G P; Ghausi O; Bastidas R B; Burton D R; Gilden D H
Cloning the antibody response in humans with inflammatory CNS disease: isolation of measles virus-specific antibodies from phage display libraries of a subacute sclerosing panencephalitis brain.
Journal of neuroimmunology 1999;94(1-2):204-11.
-
1999: Maruyama T; Parren P W; Sanchez A; Rensink I; Rodriguez L L; Khan A S; Peters C J; Burton D R
Recombinant human monoclonal antibodies to Ebola virus.
The Journal of infectious diseases 1999;179 Suppl 1():S235-9.
-
1999: Parren P W; Moore J P; Burton D R; Sattentau Q J
The neutralizing antibody response to HIV-1: viral evasion and escape from humoral immunity.
AIDS (London, England) 1999;13 Suppl A():S137-62.
-
1998: Crowe J E; Firestone C Y; Crim R; Beeler J A; Coelingh K L; Barbas C F; Burton D R; Chanock R M; Murphy B R
Monoclonal antibody-resistant mutants selected with a respiratory syncytial virus-neutralizing human antibody fab fragment (Fab 19) define a unique epitope on the fusion (F) glycoprotein.
Virology 1998;252(2):373-5.
-
1998: Parren P W; Wang M; Trkola A; Binley J M; Purtscher M; Katinger H; Moore J P; Burton D R
Antibody neutralization-resistant primary isolates of human immunodeficiency virus type 1.
Journal of virology 1998;72(12):10270-4.
-
1998: De Logu A; Williamson R A; Rozenshteyn R; Ramiro-Ibañez F; Simpson C D; Burton D R; Sanna P P
Characterization of a type-common human recombinant monoclonal antibody to herpes simplex virus with high therapeutic potential.
Journal of clinical microbiology 1998;36(11):3198-204.
-
1998: Williamson R A; Peretz D; Pinilla C; Ball H; Bastidas R B; Rozenshteyn R; Houghten R A; Prusiner S B; Burton D R
Mapping the prion protein using recombinant antibodies.
Journal of virology 1998;72(11):9413-8.
-
1998: Graus Y F; de Baets M H; Burton D R
Antiacetylcholine receptor Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies.
Annals of the New York Academy of Sciences 1998;841():414-7.
-
1998: Burton D R; Moore J P
Why do we not have an HIV vaccine and how can we make one? .
Nature medicine 1998;4(5 Suppl):495-8.
-
1998: Parren P W; Mondor I; Naniche D; Ditzel H J; Klasse P J; Burton D R; Sattentau Q J
Neutralization of human immunodeficiency virus type 1 by antibody to gp120 is determined primarily by occupancy of sites on the virion irrespective of epitope specificity.
Journal of virology 1998;72(5):3512-9.
-
1998: Salonen E M; Parren P W; Graus Y F; Lundkvist A; Fisicaro P; Vapalahti O; Kallio-Kokko H; Vaheri A; Burton D R
Human recombinant Puumala virus antibodies: cross-reaction with other hantaviruses and use in diagnostics.
The Journal of general virology 1998;79 ( Pt 4)():659-65.
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1998: Ditzel H J; Rosenkilde M M; Garred P; Wang M; Koefoed K; Pedersen C; Burton D R; Schwartz T W
The CCR5 receptor acts as an alloantigen in CCR5Delta32 homozygous individuals: identification of chemokineand HIV-1-blocking human antibodies.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(9):5241-5.
-
1998: LeBlanc J F; McLane K E; Parren P W; Burton D R; Ghazal P
Recognition properties of a sequence-specific DNA binding antibody.
Biochemistry 1998;37(17):6015-22.
-
1998: Graus Y F; Verschuuren J J; Degenhardt A; van Breda Vriesman P J; De Baets M H; Posner J B; Burton D R; Dalmau J
Selection of recombinant anti-HuD Fab fragments from a phage display antibody library of a lung cancer patient with paraneoplastic encephalomyelitis.
Journal of neuroimmunology 1998;82(2):200-9.
-
1998: Glamann J; Burton D R; Parren P W; Ditzel H J; Kent K A; Arnold C; Montefiori D; Hirsch V M
Simian immunodeficiency virus (SIV) envelope-specific Fabs with high-level homologous neutralizing activity: recovery from a long-term-nonprogressor SIV-infected macaque.
Journal of virology 1998;72(1):585-92.
-
1997: Gauduin M C; Parren P W; Weir R; Barbas C F; Burton D R; Koup R A
Passive immunization with a human monoclonal antibody protects hu-PBL-SCID mice against challenge by primary isolates of HIV-1.
Nature medicine 1997;3(12):1389-93.
-
1997: Peretz D; Williamson R A; Matsunaga Y; Serban H; Pinilla C; Bastidas R B; Rozenshteyn R; James T L; Houghten R A; Cohen F E; Prusiner S B; Burton D R
A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform.
Journal of molecular biology 1997;273(3):614-22.
-
1997: Ugolini S; Mondor I; Parren P W; Burton D R; Tilley S A; Klasse P J; Sattentau Q J
Inhibition of virus attachment to CD4+ target cells is a major mechanism of T cell line-adapted HIV-1 neutralization.
The Journal of experimental medicine 1997;186(8):1287-98.
-
1997: Burton D R
A vaccine for HIV type 1: the antibody perspective.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10018-23.
-
1997: Mo H; Stamatatos L; Ip J E; Barbas C F; Parren P W; Burton D R; Moore J P; Ho D D
Human immunodeficiency virus type 1 mutants that escape neutralization by human monoclonal antibody IgG1b12. off.
Journal of virology 1997;71(9):6869-74.
-
1997: Williamson R A; Lazzarotto T; Sanna P P; Bastidas R B; Dalla Casa B; Campisi G; Burioni R; Landini M P; Burton D R
Use of recombinant human antibody fragments for detection of cytomegalovirus antigenemia.
Journal of clinical microbiology 1997;35(8):2047-50.
-
1997: Parren P W; Gauduin M C; Koup R A; Poignard P; Sattentau Q J; Fisicaro P; Burton D R
Erratum to "Relevance of the antibody response against human immunodeficiency virus type 1 envelope to vaccine design".
Immunology letters 1997;58(2):125-32.
-
1997: Parren P W; Gauduin M C; Koup R A; Poignard P; Fisicaro P; Burton D R; Sattentau Q J
Relevance of the antibody response against human immunodeficiency virus type 1 envelope to vaccine design.
Immunology letters 1997;57(1-3):105-12.
-
1997: Graus Y F; de Baets M H; van Breda Vriesman P J; Burton D R
Anti-acetylcholine receptor Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies.
Immunology letters 1997;57(1-3):59-62.
-
1997: Ditzel H J; Parren P W; Binley J M; Sodroski J; Moore J P; Barbas C F; Burton D R
Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries.
Journal of molecular biology 1997;267(3):684-95.
-
1997: Graus Y F; de Baets M H; Parren P W; Berrih-Aknin S; Wokke J; van Breda Vriesman P J; Burton D R
Human anti-nicotinic acetylcholine receptor recombinant Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(4):1919-29.
-
1997: Burton D R; Montefiori D C
The antibody response in HIV-1 infection.
AIDS (London, England) 1997;11 Suppl A():S87-98.
-
1996: Parren P W; Fisicaro P; Labrijn A F; Binley J M; Yang W P; Ditzel H J; Barbas C F; Burton D R
In vitro antigen challenge of human antibody libraries for vaccine evaluation: the human immunodeficiency virus type 1 envelope.
Journal of virology 1996;70(12):9046-50.
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1996: Zeitlin L; Whaley K J; Sanna P P; Moench T R; Bastidas R; De Logu A; Williamson R A; Burton D R; Cone R A
Topically applied human recombinant monoclonal IgG1 antibody and its Fab and F(ab')2 fragments protect mice from vaginal transmission of HSV-2.
Virology 1996;225(1):213-5.
-
1996: Binley J M; Ditzel H J; Barbas C F; Sullivan N; Sodroski J; Parren P W; Burton D R
Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding.
AIDS research and human retroviruses 1996;12(10):911-24.
-
1996: Barbas C F; Burton D R
Selection and evolution of high-affinity human anti-viral antibodies.
Trends in biotechnology 1996;14(7):230-4.
-
1996: Ditzel H J; Itoh K; Burton D R
Determinants of polyreactivity in a large panel of recombinant human antibodies from HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(2):739-49.
-
1996: Williamson R A; Peretz D; Smorodinsky N; Bastidas R; Serban H; Mehlhorn I; DeArmond S J; Prusiner S B; Burton D R
Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):7279-82.
-
1996: Gauduin M C; Allaway G P; Maddon P J; Barbas C F; Burton D R; Koup R A
Effective ex vivo neutralization of human immunodeficiency virus type 1 in plasma by recombinant immunoglobulin molecules.
Journal of virology 1996;70(4):2586-92.
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1996: Sanna P P; De Logu A; Williamson R A; Hom Y L; Straus S E; Bloom F E; Burton D R
Protection of nude mice by passive immunization with a type-common human recombinant monoclonal antibody against HSV.
Virology 1996;215(1):101-6.
-
1995: Yang W P; Green K; Pinz-Sweeney S; Briones A T; Burton D R; Barbas C F
CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range.
Journal of molecular biology 1995;254(3):392-403.
-
1995: Sanna P P; De Logu A; Williamson R A; Samson M E; Altieri D C; Bloom F E; Burton D R
Rapid assay of phage-derived recombinant human fabs as bispecific antibodies.
Bio/technology (Nature Publishing Company) 1995;13(11):1221-4.
-
1995: Trkola A; Pomales A B; Yuan H; Korber B; Maddon P J; Allaway G P; Katinger H; Barbas C F; Burton D R; Ho D D
Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG.
Journal of virology 1995;69(11):6609-17.
-
1995: Silverman G J; Barbas S; Roben P; Burton D R
Repertoire cloning of human lupus autoantibodies.
Annals of the New York Academy of Sciences 1995;764():565-6.
-
1995: Burton D R
Phage display.
Immunotechnology : an international journal of immunological engineering 1995;1(2):87-94.
-
1995: Sanna P P; Williamson R A; De Logu A; Bloom F E; Burton D R
Directed selection of recombinant human monoclonal antibodies to herpes simplex virus glycoproteins from phage display libraries.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(14):6439-43.
-
1995: Parren P W; Ditzel H J; Gulizia R J; Binley J M; Barbas C F; Burton D R; Mosier D E
Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site.
AIDS (London, England) 1995;9(6):F1-6.
-
1995: Moreno de Alborán I; Martínéz-alonso C; Barbas C F; Burton D R; Ditzel H J
Human monoclonal Fab fragments specific for viral antigens from combinatorial IgA libraries.
Immunotechnology : an international journal of immunological engineering 1995;1(1):21-8.
-
1995: McLane K E; Burton D R; Ghazal P
Transplantation of a 17-amino acid alpha-helical DNA-binding domain into an antibody molecule confers sequence-dependent DNA recognition.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):5214-8.
-
1995: Barbas S M; Ditzel H J; Salonen E M; Yang W P; Silverman G J; Burton D R
Human autoantibody recognition of DNA.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2529-33.
-
1995: Ditzel H J; Binley J M; Moore J P; Sodroski J; Sullivan N; Sawyer L S; Hendry R M; Yang W P; Barbas C F; Burton D R
Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(2):893-906.
-
1995: Moore J P; Cao Y; Qing L; Sattentau Q J; Pyati J; Koduri R; Robinson J; Barbas C F; Burton D R; Ho D D
Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.
Journal of virology 1995;69(1):101-9.
-
1994: Burton D R; Pyati J; Koduri R; Sharp S J; Thornton G B; Parren P W; Sawyer L S; Hendry R M; Dunlop N; Nara P L
Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody.
Science (New York, N.Y.) 1994;266(5187):1024-7.
-
1994: Burton D R; Barbas C F
Human monoclonal antibodies: recent achievements.
Hospital practice (Office ed.) 1994;29(11):111, 114-6, 119 passim.
-
1994: Roben P; Moore J P; Thali M; Sodroski J; Barbas C F; Burton D R
Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.
Journal of virology 1994;68(8):4821-8.
-
1994: Barbas C F; Hu D; Dunlop N; Sawyer L; Cababa D; Hendry R M; Nara P L; Burton D R
In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):3809-13.
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1994: Ditzel H J; Barbas S M; Barbas C F; Burton D R
The nature of the autoimmune antibody repertoire in human immunodeficiency virus type 1 infection.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):3710-4.
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1994: Crowe J E; Murphy B R; Chanock R M; Williamson R A; Barbas C F; Burton D R
Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV-infected mice.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1386-90.
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1994: Burioni R; Williamson R A; Sanna P P; Bloom F E; Burton D R
Recombinant human Fab to glycoprotein D neutralizes infectivity and prevents cell-to-cell transmission of herpes simplex viruses 1 and 2 in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):355-9.
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1994: Burton D R; Barbas C F
Human antibodies from combinatorial libraries.
Advances in immunology 1994;57():191-280.
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1994: Bender E; Pilkington G R; Burton D R
Human monoclonal Fab fragments from a combinatorial library prepared from an individual with a low serum titer to a virus.
Human antibodies and hybridomas 1994;5(1-2):3-8.
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1993: Sasano M; Burton D R; Silverman G J
Molecular selection of human antibodies with an unconventional bacterial B cell antigen.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(10):5822-39.
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1993: Chanock R M; Crowe J E; Murphy B R; Burton D R
Human monoclonal antibody Fab fragments cloned from combinatorial libraries: potential usefulness in prevention and/or treatment of major human viral diseases.
Infectious agents and disease 1993;2(3):118-31.
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1993: Williamson R A; Burioni R; Sanna P P; Partridge L J; Barbas C F; Burton D R
Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):4141-5.
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1993: Burton D R; Barbas C F
Human antibodies to HIV-1 by recombinant DNA methods.
Chemical immunology 1993;56():112-26.
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1992: Lerner R A; Kang A S; Bain J D; Burton D R; Barbas C F
Antibodies without immunization.
Science (New York, N.Y.) 1992;258(5086):1313-4.
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1992: Collet T A; Roben P; O'Kennedy R; Barbas C F; Burton D R; Lerner R A
A binary plasmid system for shuffling combinatorial antibody libraries.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10026-30.
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1992: Barbas C F; Crowe J E; Cababa D; Jones T M; Zebedee S L; Murphy B R; Chanock R M; Burton D R
Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10164-8.
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1992: Burton D R
Human monoclonal antibodies: achievement and potential.
Hospital practice (Office ed.) 1992;27(8):67-74.
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1992: Zebedee S L; Barbas C F; Hom Y L; Caothien R H; Graff R; DeGraw J; Pyati J; LaPolla R; Burton D R; Lerner R A
Human combinatorial antibody libraries to hepatitis B surface antigen.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(8):3175-9.
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1992: Duchosal M A; Eming S A; Fischer P; Leturcq D; Barbas C F; McConahey P J; Caothien R H; Thornton G B; Dixon F J; Burton D R
Immunization of hu-PBL-SCID mice and the rescue of human monoclonal Fab fragments through combinatorial libraries.
Nature 1992;355(6357):258-62.
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1992: Burton D R; Woof J M
Human antibody effector function.
Advances in immunology 1992;51():1-84.
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1991: Kang A S; Jones T M; Burton D R
Antibody redesign by chain shuffling from random combinatorial immunoglobulin libraries.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11120-3.
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1991: Lerner R A; Barbas C F; Kang A S; Burton D R
On the use of combinatorial antibody libraries to clone the "fossil record" of an individual's immune response.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(21):9705-6.
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1991: Burton D R; Barbas C F; Persson M A; Koenig S; Chanock R M; Lerner R A
A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10134-7.
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