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Jan-�ke GUSTAFSSON

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Qin Yan; Dalen Knut Tomas; Gustafsson Jan-Ake; Nebb Hilde I
Regulation of hepatic fatty acid elongase 5 by LXRalpha-SREBP-1c.
Gabbi Chiara; Warner Margaret; Gustafsson Jan-Ake
Minireview: liver X receptor beta: emerging roles in physiology and diseases.
Tomihara Kazuya; Soga Tomoko; Nomura Masayoshi; Korach Kenneth S; Gustafsson Jan-Ake; Pfaff Donald W; Ogawa Sonoko
Effect of ER-beta gene disruption on estrogenic regulation of anxiety in female mice.

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All Publications

2009: Qin Yan; Dalen Knut Tomas; Gustafsson Jan-Ake; Nebb Hilde I
Regulation of hepatic fatty acid elongase 5 by LXRalpha-SREBP-1c.
Biochimica et biophysica acta 2009;1791(2):140-7.
2009: Gabbi Chiara; Warner Margaret; Gustafsson Jan-Ake
Minireview: liver X receptor beta: emerging roles in physiology and diseases.
Molecular endocrinology (Baltimore, Md.) 2009;23(2):129-36.
2009: Tomihara Kazuya; Soga Tomoko; Nomura Masayoshi; Korach Kenneth S; Gustafsson Jan-Ake; Pfaff Donald W; Ogawa Sonoko
Effect of ER-beta gene disruption on estrogenic regulation of anxiety in female mice.
Physiology & behavior 2009;96(2):300-6.
2009: Sugiyama N; Andersson S; Lathe R; Fan X; Alonso-Magdalena P; Schwend T; Nalvarte I; Warner M; Gustafsson J-A
Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain.
Molecular psychiatry 2009;14(2):223-32, 117.
2009: Ogasawara Kiyomoto; Nogami Haruo; Tsuda Mumeko C; Gustafsson Jan-Ake; Korach Kenneth S; Ogawa Sonoko; Harigaya Toshio; Hisano Setsuji
Hormonal regulation of prolactin cell development in the fetal pituitary gland of the mouse.
Endocrinology 2009;150(2):1061-8.
2009: Kim Hyun-Jin; Andersson Leif C; Bouton Didier; Warner Margaret; Gustafsson Jan-Ake
Stromal growth and epithelial cell proliferation in ventral prostates of liver X receptor knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):558-63.
2009: Rüegg Joëlle; Penttinen-Damdimopoulou Pauliina; Mäkelä Sari; Pongratz Ingemar; Gustafsson Jan-Ake
Receptors mediating toxicity and their involvement in endocrine disruption.
EXS 2009;99():289-323.
2008: Helguero Luisa A; Lindberg Karolina; Gardmo Cissi; Schwend Thomas; Gustafsson Jan-Ake; Haldosén Lars-Arne
Different roles of estrogen receptors alpha and beta in the regulation of E-cadherin protein levels in a mouse mammary epithelial cell line.
Cancer research 2008;68(21):8695-704.
2008: Dahlman Ingrid; Vaxillaire Martine; Nilsson Maria; Lecoeur Cecile; Gu Harvest F; Cavalcanti-Proença Christine; Efendic Suad; Ostenson Claes G; Brismar Kerstin; Charpentier Guillaume; Gustafsson Jan-Ake; Froguel Philippe; Dahlman-Wright Karin; Steffensen Knut R
Estrogen receptor alpha gene variants associate with type 2 diabetes and fasting plasma glucose.
Pharmacogenetics and genomics 2008;18(11):967-75.
2008: Lundholm L; Bryzgalova G; Gao H; Portwood N; Fält S; Berndt K D; Dicker A; Galuska D; Zierath J R; Gustafsson J-A; Efendic S; Dahlman-Wright K; Khan A
The estrogen receptor {alpha}-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice; potential molecular mechanisms.
The Journal of endocrinology 2008;199(2):275-86.
2008: Bryzgalova Galyna; Lundholm Lovisa; Portwood Neil; Gustafsson Jan-Ake; Khan Akhtar; Efendic Suad; Dahlman-Wright Karin
Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice.
American journal of physiology. Endocrinology and metabolism 2008;295(4):E904-12.
2008: Sotoca Ana M Covaleda; van den Berg Hans; Vervoort Jacques; van der Saag Paul; Ström Anders; Gustafsson Jan-Ake; Rietjens Ivonne; Murk Albertinka J
Influence of cellular ERalpha/ERbeta ratio on the ERalpha-agonist induced proliferation of human T47D breast cancer cells.
Toxicological sciences : an official journal of the Society of Toxicology 2008;105(2):303-11.
2008: Gabbi Chiara; Kim Hyun-Jin; Hultenby Kjell; Bouton Didier; Toresson Gudrun; Warner Margaret; Gustafsson Jan-Ake
Pancreatic exocrine insufficiency in LXRbeta-/- mice is associated with a reduction in aquaporin-1 expression.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):15052-7.
2008: Fan Xiaotang; Kim Hyun-Jin; Bouton Didier; Warner Margaret; Gustafsson Jan-Ake
Expression of liver X receptor beta is essential for formation of superficial cortical layers and migration of later-born neurons.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(36):13445-50.
2008: Zhou Xin-Wen; Gustafsson Jan-Ake; Tanila Heikki; Bjorkdahl Cecilia; Liu Rong; Winblad Bengt; Pei Jin-Jing
Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A.
Neurobiology of disease 2008;31(3):386-94.
2008: Morani A; Warner M; Gustafsson J-A
Biological functions and clinical implications of oestrogen receptors alfa and beta in epithelial tissues.
Journal of internal medicine 2008;264(2):128-42.
2008: Madsen Lise; Petersen Rasmus K; Steffensen Knut R; Pedersen Lone M; Hallenborg Philip; Ma Tao; Frøyland Livar; Døskeland Stein Ove; Gustafsson Jan-Ake; Kristiansen Karsten
Activation of liver X receptors prevents statin-induced death of 3T3-L1 preadipocytes.
The Journal of biological chemistry 2008;283(33):22723-36.
2008: Lundholm Lovisa; Zang Hong; Hirschberg Angelica Lindén; Gustafsson Jan-Ake; Arner Peter; Dahlman-Wright Karin
Key lipogenic gene expression can be decreased by estrogen in human adipose tissue.
Fertility and sterility 2008;90(1):44-8.
2008: Foryst-Ludwig Anna; Clemenz Markus; Hohmann Stephan; Hartge Martin; Sprang Christiane; Frost Nikolaj; Krikov Maxim; Bhanot Sanjay; Barros Rodrigo; Morani Andrea; Gustafsson Jan-Ake; Unger Thomas; Kintscher Ulrich
Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma.
PLoS genetics 2008;4(6):e1000108.
2008: Kavaliers Martin; Devidze Nino; Choleris Elena; Fudge Melissa; Gustafsson Jan-Ake; Korach Kenneth S; Pfaff Donald W; Ogawa Sonoko
Estrogen receptors alpha and beta mediate different aspects of the facilitatory effects of female cues on male risk taking.
Psychoneuroendocrinology 2008;33(5):634-42.
2008: Wahlgren Aida; Svechnikov Konstantin; Strand Mona-Lisa; Jahnukainen Kirsi; Parvinen Martti; Gustafsson Jan-Ake; Söder Olle
Estrogen receptor beta selective ligand 5alpha-Androstane-3beta, 17beta-diol stimulates spermatogonial deoxyribonucleic acid synthesis in rat seminiferous epithelium in vitro.
Endocrinology 2008;149(6):2917-22.
2008: Lundin Annelie; Bok Chek Mei; Aronsson Linda; Björkholm Britta; Gustafsson Jan-Ake; Pott Sebastian; Arulampalam Velmurugesan; Hibberd Martin; Rafter Joseph; Pettersson Sven
Gut flora, Toll-like receptors and nuclear receptors: a tripartite communication that tunes innate immunity in large intestine.
Cellular microbiology 2008;10(5):1093-103.
2008: Meltser Inna; Tahera Yeasmin; Simpson Evan; Hultcrantz Malou; Charitidi Konstantina; Gustafsson Jan-Ake; Canlon Barbara
Estrogen receptor beta protects against acoustic trauma in mice.
The Journal of clinical investigation 2008;118(4):1563-70.
2008: Archer Amena; Lauter Gilbert; Hauptmann Giselbert; Mode Agneta; Gustafsson Jan-Ake
Transcriptional activity and developmental expression of liver X receptor (lxr) in zebrafish.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(4):1090-8.
2008: Antonson Per; Jakobsson Tomas; Almlöf Tova; Guldevall Karolin; Steffensen Knut R; Gustafsson Jan-Ake
RAP250 is a coactivator in the transforming growth factor beta signaling pathway that interacts with Smad2 and Smad3.
The Journal of biological chemistry 2008;283(14):8995-9001.
2008: Asadi Abolfazl; Hedman Erik; Widén Christina; Zilliacus Johanna; Gustafsson Jan-Ake; Wikström Ann-Charlotte
FMS-like tyrosine kinase 3 interacts with the glucocorticoid receptor complex and affects glucocorticoid dependent signaling.
Biochemical and biophysical research communications 2008;368(3):569-74.
2008: Lundholm Lovisa; Putnik Milica; Otsuki Michio; Andersson Sandra; Ohlsson Claes; Gustafsson Jan-Ake; Dahlman-Wright Karin
Effects of estrogen on gene expression profiles in mouse hypothalamus and white adipose tissue: target genes include glutathione peroxidase 3 and cell death-inducing DNA fragmentation factor, alpha-subunit-like effector A.
The Journal of endocrinology 2008;196(3):547-57.
2008: Liu Yawen; Gao Hui; Marstrand Troels Torben; Ström Anders; Valen Eivind; Sandelin Albin; Gustafsson Jan-Ake; Dahlman-Wright Karin
The genome landscape of ERalpha- and ERbeta-binding DNA regions.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2604-9.
2008: Kim Hyun-Jin; Fan Xiaotang; Gabbi Chiara; Yakimchuk Konstantin; Parini Paolo; Warner Margaret; Gustafsson Jan-Ake
Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(6):2094-9.
2008: Are Alexandra; Aronsson Linda; Wang Shugui; Greicius Gediminas; Lee Yuan Kun; Gustafsson Jan-Ake; Pettersson Sven; Arulampalam Velmurugesan
Enterococcus faecalis from newborn babies regulate endogenous PPARgamma activity and IL-10 levels in colonic epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(6):1943-8.
2008: Williams C; Edvardsson K; Lewandowski S A; Ström A; Gustafsson J-A
A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells.
Oncogene 2008;27(7):1019-32.
2008: Liu R; Zhou X-W; Tanila H; Bjorkdahl C; Wang J-Z; Guan Z-Z; Cao Y; Gustafsson J-A; Winblad B; Pei J-J
Phosphorylated PP2A (tyrosine 307) is associated with Alzheimer neurofibrillary pathology.
Journal of cellular and molecular medicine 2008;12(1):241-57.
2008: Cai Wen; Rambaud Juliette; Teboul Michèle; Masse Ingrid; Benoit Gerard; Gustafsson Jan-Ake; Delaunay Franck; Laudet Vincent; Pongratz Ingemar
Expression levels of estrogen receptor beta are modulated by components of the molecular clock.
Molecular and cellular biology 2008;28(2):784-93.
2008: Douglas Gillian; Cruz M Natalia; Poston Lucilla; Gustafsson Jan-Ake; Kublickiene Karolina
Functional characterization and sex differences in small mesenteric arteries of the estrogen receptor-beta knockout mouse.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;294(1):R112-20.
2008: Gao Hui; Fält Susann; Sandelin Albin; Gustafsson Jan-Ake; Dahlman-Wright Karin
Genome-wide identification of estrogen receptor alpha-binding sites in mouse liver.
Molecular endocrinology (Baltimore, Md.) 2008;22(1):10-22.
2008: Damdimopoulos Anastasios E; Spyrou Giannis; Gustafsson Jan-Ake
Ligands differentially modify the nuclear mobility of estrogen receptors alpha and beta.
Endocrinology 2008;149(1):339-45.
2008: Chandanos Evangelos; Rubio Carlos A; Lindblad Mats; Jia Chongqi; Tsolakis Apostolos V; Warner Margaret; Gustafsson Jan-Ake; Lagergren Jesper
Endogenous estrogen exposure in relation to distribution of histological type and estrogen receptors in gastric adenocarcinoma.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2008;11(3):168-74.
2008: Zhao Chunyan; Dahlman-Wright Karin; Gustafsson Jan-Ake
Estrogen receptor beta: an overview and update.
Nuclear receptor signaling 2008;6():e003.
2007: Windahl S H; Lagerquist M K; Andersson N; Jochems C; Kallkopf A; Håkansson C; Inzunza J; Gustafsson J-A; van der Saag P T; Carlsten H; Pettersson K; Ohlsson C
Identification of target cells for the genomic effects of estrogens in bone.
Endocrinology 2007;148(12):5688-95.
2007: Sanyal Sabyasachi; Båvner Ann; Haroniti Anna; Nilsson Lisa-Mari; Lundåsen Thomas; Rehnmark Stefan; Witt Michael Robin; Einarsson Curt; Talianidis Iannis; Gustafsson Jan-Ake; Treuter Eckardt
Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(40):15665-70.
2007: Kotokorpi Pia; Ellis Ewa; Parini Paolo; Nilsson Lisa-Mari; Strom Stephen; Steffensen Knut R; Gustafsson Jan-Ake; Mode Agneta
Physiological differences between human and rat primary hepatocytes in response to liver X receptor activation by 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride (GW3965).
Molecular pharmacology 2007;72(4):947-55.
2007: Matthews Jason; Wihlén Björn; Heldring Nina; MacPherson Laura; Helguero Luisa; Treuter Eckardt; Haldosén Lars-Arne; Gustafsson Jan-Ake
Co-planar 3,3',4,4',5-pentachlorinated biphenyl and non-co-planar 2,2',4,6,6'-pentachlorinated biphenyl differentially induce recruitment of oestrogen receptor alpha to aryl hydrocarbon receptor target genes.
The Biochemical journal 2007;406(2):343-53.
2007: Kato Sawako; Lindholm Bengt; Axelsson Jonas; Qureshi Rashid A; Barany Peter; Heimbürger Olof; Gustafsson Jan-Ake; Stenvinkel Peter; Nordfors Louise
Association between oestrogen receptor alpha gene polymorphism and mortality in female end-stage renal disease patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(9):2571-7.
2007: Fan Xiaotang; Kim Hyun-Jin; Warner Margaret; Gustafsson Jan-Ake
Estrogen receptor beta is essential for sprouting of nociceptive primary afferents and for morphogenesis and maintenance of the dorsal horn interneurons.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(34):13696-701.
2007: Heldring Nina; Pike Ashley; Andersson Sandra; Matthews Jason; Cheng Guojun; Hartman Johan; Tujague Michel; Ström Anders; Treuter Eckardt; Warner Margaret; Gustafsson Jan-Ake
Estrogen receptors: how do they signal and what are their targets.
Physiological reviews 2007;87(3):905-31.
2007: Jakobsson Tomas; Osman Waffa; Gustafsson Jan-Ake; Zilliacus Johanna; Wärnmark Anette
Molecular basis for repression of liver X receptor-mediated gene transcription by receptor-interacting protein 140.
The Biochemical journal 2007;405(1):31-9.
2007: Imamov Otabek; Yakimchuk Konstantin; Morani Andrea; Schwend Thomas; Wada-Hiraike Osamu; Razumov Sergei; Warner Margaret; Gustafsson Jan-Ake
Estrogen receptor beta-deficient female mice develop a bladder phenotype resembling human interstitial cystitis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9806-9.
2007: Damdimopoulos Anastasios E; Gustafsson Jan-Ake; Spyrou Giannis
Nuclear immobilization of DsRed1 tagged proteins: a novel tool for studying DNA-protein interactions?
Biochimica et biophysica acta 2007;1773(6):687-90.
2007: Cheng Guojun; Wilczek Brigitte; Warner Margaret; Gustafsson Jan-Ake; Landgren Britth-Marie
Isoflavone treatment for acute menopausal symptoms.
Menopause (New York, N.Y.) 2007;14(3 Pt 1):468-73.
2007: Zhao Chunyan; Matthews Jason; Tujague Michel; Wan Jinghong; Ström Anders; Toresson Gudrun; Lam Eric W-F; Cheng Guojun; Gustafsson Jan-Ake; Dahlman-Wright Karin
Estrogen receptor beta2 negatively regulates the transactivation of estrogen receptor alpha in human breast cancer cells.
Cancer research 2007;67(8):3955-62.
2007: Heldring Nina; Pawson Tanya; McDonnell Donald; Treuter Eckardt; Gustafsson Jan-Ake; Pike Ashley C W
Structural insights into corepressor recognition by antagonist-bound estrogen receptors.
The Journal of biological chemistry 2007;282(14):10449-55.
2007: Treuter Eckardt; Gustafsson Jan-Ake
Wrestling rules in transrepression: as easy as SUMO-1, -2, -3?
Molecular cell 2007;25(2):178-80.
2007: Inzunza José; Morani Andrea; Cheng Guojun; Warner Margaret; Hreinsson Julius; Gustafsson Jan-Ake; Hovatta Outi
Ovarian wedge resection restores fertility in estrogen receptor beta knockout (ERbeta-/-) mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(2):600-5.
2007: Nilsson Maria; Dahlman Ingrid; Jiao Hong; Gustafsson Jan-Ake; Arner Peter; Dahlman-Wright Karin
Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis--a cohort study.
BMC medical genetics 2007;8():73.
2007: Nilsson Maria; Dahlman-Wright Karin; Karelmo Charlotta; Ebeling Martin; Gustafsson Jan-Ake; Steffensen Knut R
Elk1 and SRF transcription factors convey basal transcription and mediate glucose response via their binding sites in the human LXRB gene promoter.
Nucleic acids research 2007;35(14):4858-68.
2007: Lin Chin-Yo; Ström Anders; Li Kong Say; Kietz Silke; Thomsen Jane S; Tee Jason B S; Vega Vinsensius B; Miller Lance D; Smeds Johanna; Bergh Jonas; Gustafsson Jan-Ake; Liu Edison T
Inhibitory effects of estrogen receptor beta on specific hormone-responsive gene expression and association with disease outcome in primary breast cancer.
Breast cancer research : BCR 2007;9(2):R25.
2006: Fan Xiaotang; Warner Margaret; Gustafsson Jan-Ake
Estrogen receptor beta expression in the embryonic brain regulates development of calretinin-immunoreactive GABAergic interneurons.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(51):19338-43.
2006: Roelens Frederik; Heldring Nina; Dhooge Willem; Bengtsson Martin; Comhaire Frank; Gustafsson Jan-Ake; Treuter Eckardt; De Keukeleire Denis
Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta.
Journal of medicinal chemistry 2006;49(25):7357-65.
2006: Hartman Johan; Lindberg Karolina; Morani Andrea; Inzunza José; Ström Anders; Gustafsson Jan-Ake
Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts.
Cancer research 2006;66(23):11207-13.
2006: Dahlman-Wright Karin; Cavailles Vincent; Fuqua Suzanne A; Jordan V Craig; Katzenellenbogen John A; Korach Kenneth S; Maggi Adriana; Muramatsu Masami; Parker Malcolm G; Gustafsson Jan-Ake
International Union of Pharmacology. LXIV. Estrogen receptors.
Pharmacological reviews 2006;58(4):773-81.
2006: Dahlman Ingrid; Nilsson Maria; Jiao Hong; Hoffstedt Johan; Lindgren Cecilia M; Humphreys Keith; Kere Juha; Gustafsson Jan-Ake; Arner Peter; Dahlman-Wright Karin
Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity.
Pharmacogenetics and genomics 2006;16(12):881-9.
2006: Wada-Hiraike O; Warner M; Gustafsson J-A
New developments in oestrogen signalling in colonic epithelium.
Biochemical Society transactions 2006;34(Pt 6):1114-6.
2006: Luksha Leonid; Poston Lucilla; Gustafsson Jan-Ake; Hultenby Kjell; Kublickiene Karolina
The oestrogen receptor beta contributes to sex related differences in endothelial function of murine small arteries via EDHF.
The Journal of physiology 2006;577(Pt 3):945-55.
2006: Wada-Hiraike Osamu; Hiraike Haruko; Okinaga Hiroko; Imamov Otabek; Barros Rodrigo P A; Morani Andrea; Omoto Yoko; Warner Margaret; Gustafsson Jan-Ake
Role of estrogen receptor beta in uterine stroma and epithelium: Insights from estrogen receptor beta-/- mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18350-5.
2006: Ohnemus Ulrich; Uenalan Murat; Inzunza José; Gustafsson Jan-Ake; Paus Ralf
The hair follicle as an estrogen target and source.
Endocrine reviews 2006;27(6):677-706.
2006: Quinet Elaine M; Savio Dawn A; Halpern Anita R; Chen Liang; Schuster Gertrude U; Gustafsson Jan-Ake; Basso Mike D; Nambi Ponnal
Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting.
Molecular pharmacology 2006;70(4):1340-9.
2006: Gustafsson Jan-Ake
Comments to the paper "tools to evaluate estrogenic potency of dietary phytoestrogens: A consensus paper from the EU Thematic Network "Phytohealth" (QLKI-2002-2453)".
Genes & nutrition 2006;1(3-4):159-60.
2006: Barros Rodrigo P A; Machado Ubiratan Fabres; Gustafsson Jan-Ake
Estrogen receptors: new players in diabetes mellitus.
Trends in molecular medicine 2006;12(9):425-31.
2006: Schuster Gertrud U; Johansson Lisen; Kietz Silke; Stulnig Thomas M; Parini Paolo; Gustafsson Jan-Ake
Improved metabolic control by depletion of Liver X Receptors in mice.
Biochemical and biophysical research communications 2006;348(1):176-82.
2006: Steffensen Knut R; Robertson Kirsten; Gustafsson Jan-Ake; Andersen Claus Yding
Reduced fertility and inability of oocytes to resume meiosis in mice deficient of the Lxr genes.
Molecular and cellular endocrinology 2006;256(1-2):9-16.
2006: Robertson Kirsten M; Norgård Maria; Windahl Sara H; Hultenby Kjell; Ohlsson Claes; Andersson Göran; Gustafsson Jan-Ake
Cholesterol-sensing receptors, liver X receptor alpha and beta, have novel and distinct roles in osteoclast differentiation and activation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(8):1276-87.
2006: Helguero Luisa A; Hedengran Faulds Malin; Förster Carola; Gustafsson Jan-Ake; Haldosén Lars-Arne
DAX-1 expression is regulated during mammary epithelial cell differentiation.
Endocrinology 2006;147(7):3249-59.
2006: Gao Hui; Bryzgalova Galina; Hedman Erik; Khan Akhtar; Efendic Suad; Gustafsson Jan-Ake; Dahlman-Wright Karin
Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3.
Molecular endocrinology (Baltimore, Md.) 2006;20(6):1287-99.
2006: Morani Andrea; Barros Rodrigo P A; Imamov Otabek; Hultenby Kjell; Arner Anders; Warner Margaret; Gustafsson Jan-Ake
Lung dysfunction causes systemic hypoxia in estrogen receptor beta knockout (ERbeta-/-) mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(18):7165-9.
2006: Hedman Erik; Widén Christina; Asadi Abolfazl; Dinnetz Ingrid; Schröder Wolfgang P; Gustafsson Jan-Ake; Wikström Ann-Charlotte
Proteomic identification of glucocorticoid receptor interacting proteins.
Proteomics 2006;6(10):3114-26.
2006: Zhao Chunyan; Gustafsson Jan-Ake; Dahlman-Wright Karin
Functional characterization of a novel variant of estrogen receptor beta identified in screening of DNA derived from African Americans.
Pharmacogenetics and genomics 2006;16(5):379-83.
2006: Schwend Thomas; Gustafsson Jan-Ake
False positives in MALDI-TOF detection of ERbeta in mitochondria.
Biochemical and biophysical research communications 2006;343(3):707-11.
2006: Movérare-Skrtic Sofia; Venken Katrien; Andersson Niklas; Lindberg Marie K; Svensson Johan; Swanson Charlotte; Vanderschueren Dirk; Oscarsson Jan; Gustafsson Jan-Ake; Ohlsson Claes
Dihydrotestosterone treatment results in obesity and altered lipid metabolism in orchidectomized mice.
Obesity (Silver Spring, Md.) 2006;14(4):662-72.
2006: Nomura Masayoshi; Andersson Sandra; Korach Kenneth S; Gustafsson Jan-Ake; Pfaff Donald W; Ogawa Sonoko
Estrogen receptor-beta gene disruption potentiates estrogen-inducible aggression but not sexual behaviour in male mice.
The European journal of neuroscience 2006;23(7):1860-8.
2006: Yngve Agneta; Hambraeus Leif; Lissner Lauren; Serra Majem Lluis; Vaz de Almeida Maria Daniel; Berg Christina; Hughes Roger; Cannon Geoffrey; Thorsdottir Inga; Kearney John; Gustafsson Jan-Ake; Rafter Joseph; Elmadfa Ibrahim; Kennedy Nick
The Women's Health Initiative. What is on trial: nutrition and chronic disease? Or misinterpreted science, media havoc and the sound of silence from peers?
Public health nutrition 2006;9(2):269-72.
2006: Zanotti Ilaria; Potì Francesco; Favari Elda; Steffensen Knut R; Gustafsson Jan-Ake; Bernini Franco
Pitavastatin effect on ATP binding cassette A1-mediated lipid efflux from macrophages: evidence for liver X receptor (LXR)-dependent and LXR-independent mechanisms of activation by cAMP.
The Journal of pharmacology and experimental therapeutics 2006;317(1):395-401.
2006: Thellenberg-Karlsson Camilla; Lindström Sara; Malmer Beatrice; Wiklund Fredrik; Augustsson-Bälter Katarina; Adami Hans-Olov; Stattin Par; Nilsson Maria; Dahlman-Wright Karin; Gustafsson Jan-Ake; Grönberg Henrik
Estrogen receptor beta polymorphism is associated with prostate cancer risk.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(6):1936-41.
2006: Hall Wendy L; Vafeiadou Katerina; Hallund Jesper; Bugel Susanne; Reimann Manja; Koebnick Corinna; Zunft H-J Franz; Ferrari Marika; Branca Francesco; Dadd Tony; Talbot Duncan; Powell Jonathan; Minihane Anne-Marie; Cassidy Aedin; Nilsson Maria; Dahlman-Wright Karin; Gustafsson Jan-Ake; Williams Christine M
Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women: interactions with genotype and equol production.
The American journal of clinical nutrition 2006;83(3):592-600.
2006: Bryzgalova G; Gao H; Ahren B; Zierath J R; Galuska D; Steiler T L; Dahlman-Wright K; Nilsson S; Gustafsson J-A; Efendic S; Khan A
Evidence that oestrogen receptor-alpha plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver.
Diabetologia 2006;49(3):588-97.
2006: Matthews Jason; Wihlén Björn; Tujague Michel; Wan Jinghong; Ström Anders; Gustafsson Jan-Ake
Estrogen receptor (ER) beta modulates ERalpha-mediated transcriptional activation by altering the recruitment of c-Fos and c-Jun to estrogen-responsive promoters.
Molecular endocrinology (Baltimore, Md.) 2006;20(3):534-43.
2006: Wada-Hiraike Osamu; Imamov Otabek; Hiraike Haruko; Hultenby Kjell; Schwend Thomas; Omoto Yoko; Warner Margaret; Gustafsson Jan-Ake
Role of estrogen receptor beta in colonic epithelium.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2959-64.
2006: Jiménez Alberto; Pelto-Huikko Markku; Gustafsson Jan-Ake; Miranda-Vizuete Antonio
Characterization of human thioredoxin-like-1: potential involvement in the cellular response against glucose deprivation.
FEBS letters 2006;580(3):960-7.
2006: Shim Gil-Jin; Gherman Delia; Kim Hyun-Jin; Omoto Yoko; Iwase Hirotaka; Bouton Didier; Kis Loránd Levente; Andersson Christina Thulin; Warner Margaret; Gustafsson Jan-Ake
Differential expression of oestrogen receptors in human secondary lymphoid tissues.
The Journal of pathology 2006;208(3):408-14.
2006: Warner Margaret; Gustafsson Jan-Ake
Nongenomic effects of estrogen: why all the uncertainty?
Steroids 2006;71(2):91-5.
2006: Cruz Maria Natalia; Douglas Gillian; Gustafsson Jan-Ake; Poston Lucilla; Kublickiene Karolina
Dilatory responses to estrogenic compounds in small femoral arteries of male and female estrogen receptor-beta knockout mice.
American journal of physiology. Heart and circulatory physiology 2006;290(2):H823-9.
2006: Barros Rodrigo P A; Machado Ubiratan F; Warner Margaret; Gustafsson Jan-Ake
Muscle GLUT4 regulation by estrogen receptors ERbeta and ERalpha.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1605-8.
2006: Hearns-Stokes Rhonda; Mayers Chantal; Zahn Christopher; Cruess David; Gustafsson Jan-Ake; Segars James; Nieman Lynnette
Expression of the proto-oncoprotein breast cancer nuclear receptor auxiliary factor (Brx) is altered in eutopic endometrium of women with endometriosis.
Fertility and sterility 2006;85(1):63-70.
2006: Matthews Jason; Gustafsson Jan-Ake
Estrogen receptor and aryl hydrocarbon receptor signaling pathways.
Nuclear receptor signaling 2006;4():e016.
2006: Mode Agneta; Gustafsson Jan-Ake
Sex and the liver - a journey through five decades.
Drug metabolism reviews 2006;38(1-2):197-207.
2005: Osterlund Marie K; Witt Michael-Robin; Gustafsson Jan-Ake
Estrogen action in mood and neurodegenerative disorders: estrogenic compounds with selective properties-the next generation of therapeutics.
Endocrine 2005;28(3):235-42.
2005: Hall Wendy L; Vafeiadou Katerina; Hallund Jesper; Bügel Susanne; Koebnick Corinna; Reimann Manja; Ferrari Marika; Branca Francesco; Talbot Duncan; Dadd Tony; Nilsson Maria; Dahlman-Wright Karin; Gustafsson Jan-Ake; Minihane Anne-Marie; Williams Christine M
Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production.
The American journal of clinical nutrition 2005;82(6):1260-8; quiz 1365-6.
2005: Båvner Ann; Sanyal Sabyasachi; Gustafsson Jan-Ake; Treuter Eckardt
Transcriptional corepression by SHP: molecular mechanisms and physiological consequences.
Trends in endocrinology and metabolism: TEM 2005;16(10):478-88.
2005: Liu Xuan; Steffensen Knut R; Sanna Alessandra; Arru Giannina; Fois Maria Laura; Rosati Giulio; Sotgiu Stefano; Link Hans; Gustafsson Jan-Ake; Huang Yu-Min
Anti-inflammatory nuclear receptor superfamily in multiple sclerosis patients from Sardinia and Sweden.
Neurobiology of disease 2005;20(3):961-8.
2005: Maguire Paula; Margolin Sara; Skoglund Johanna; Sun Xiao-Feng; Gustafsson Jan-Ake; Børresen-Dale Anne-Lise; Lindblom Annika
Estrogen receptor beta (ESR2) polymorphisms in familial and sporadic breast cancer.
Breast cancer research and treatment 2005;94(2):145-52.
2005: Luksha Leonid; Poston Lucilla; Gustafsson Jan-Ake; Aghajanova Lusine; Kublickiene Karolina
Gender-specific alteration of adrenergic responses in small femoral arteries from estrogen receptor-beta knockout mice.
Hypertension 2005;46(5):1163-8.
2005: Imamov Otabek; Shim Gil-Jin; Warner Margaret; Gustafsson Jan-Ake
Estrogen receptor beta in health and disease.
Biology of reproduction 2005;73(5):866-71.
2005: Helguero Luisa A; Faulds Malin Hedengran; Gustafsson Jan-Ake; Haldosén Lars-Arne
Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11.
Oncogene 2005;24(44):6605-16.
2005: Matthews Jason; Almlöf Tova; Kietz Silke; Leers Jörg; Gustafsson Jan-Ake
Estrogen receptor-alpha regulates SOCS-3 expression in human breast cancer cells.
Biochemical and biophysical research communications 2005;335(1):168-74.
2005: Gnerre Carmela; Schuster Gertrud U; Roth Adrian; Handschin Christoph; Johansson Lisen; Looser Renate; Parini Paolo; Podvinec Michael; Robertsson Kirsten; Gustafsson Jan-Ake; Meyer Urs A
LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver.
Journal of lipid research 2005;46(8):1633-42.
2005: Matthews Jason; Wihlén Björn; Thomsen Jane; Gustafsson Jan-Ake
Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters.
Molecular and cellular biology 2005;25(13):5317-28.
2005: Vanderhorst Veronique G J M; Gustafsson Jan-Ake; Ulfhake Brun
Estrogen receptor-alpha and -beta immunoreactive neurons in the brainstem and spinal cord of male and female mice: relationships to monoaminergic, cholinergic, and spinal projection systems.
The Journal of comparative neurology 2005;488(2):152-79.
2005: Ulven Stine Marie; Dalen Knut Tomas; Gustafsson Jan-Ake; Nebb Hilde Irene
LXR is crucial in lipid metabolism.
Prostaglandins, leukotrienes, and essential fatty acids 2005;73(1):59-63.
2005: Surugiu-Wärnmark Ioana; Wärnmark Anette; Toresson Gudrun; Gustafsson Jan-Ake; Bülow Leif
Selection of DNA aptamers against rat liver X receptors.
Biochemical and biophysical research communications 2005;332(2):512-7.
2005: Zhao Chunyan; Toresson Gudrun; Xu Li; Koehler Konrad F; Gustafsson Jan-Ake; Dahlman-Wright Karin
Mouse estrogen receptor beta isoforms exhibit differences in ligand selectivity and coactivator recruitment.
Biochemistry 2005;44(22):7936-44.
2005: Gustafsson Jan-Ake
Steroids and the scientist.
Molecular endocrinology (Baltimore, Md.) 2005;19(6):1412-7.
2005: Gerin Isabelle; Dolinsky Vernon W; Shackman Jonathan G; Kennedy Robert T; Chiang Shian-Huey; Burant Charles F; Steffensen Knut R; Gustafsson Jan-Ake; MacDougald Ormond A
LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function.
The Journal of biological chemistry 2005;280(24):23024-31.
2005: Robertson Kirsten M; Schuster Gertrud U; Steffensen Knut R; Hovatta Outi; Meaney Steve; Hultenby Kjell; Johansson Lisen C; Svechnikov Konstantin; Söder Olle; Gustafsson Jan-Ake
The liver X receptor-{beta} is essential for maintaining cholesterol homeostasis in the testis.
Endocrinology 2005;146(6):2519-30.
2005: Esslimani-Sahla Majida; Kramar Andrew; Simony-Lafontaine Joelle; Warner Margaret; Gustafsson Jan-Ake; Rochefort Henri
Increased estrogen receptor betacx expression during mammary carcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(9):3170-4.
2005: Koehler Konrad F; Helguero Luisa A; Haldosén Lars-Arne; Warner Margaret; Gustafsson Jan-Ake
Reflections on the discovery and significance of estrogen receptor beta.
Endocrine reviews 2005;26(3):465-78.
2005: Jiménez Alberto; Prieto-Alamo María J; Fuentes-Almagro Carlos A; Jurado Juan; Gustafsson Jan-Ake; Pueyo Carmen; Miranda-Vizuete Antonio
Absolute mRNA levels and transcriptional regulation of the mouse testis-specific thioredoxins.
Biochemical and biophysical research communications 2005;330(1):65-74.
2005: Berkenstam Anders; Gustafsson Jan-Ake
Nuclear receptors and their relevance to diseases related to lipid metabolism.
Current opinion in pharmacology 2005;5(2):171-6.
2005: Kudwa Andrea E; Bodo Cristian; Gustafsson Jan-Ake; Rissman Emilie F
A previously uncharacterized role for estrogen receptor beta: defeminization of male brain and behavior.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4608-12.
2005: Andersson Sandra; Gustafsson Nina; Warner Margaret; Gustafsson Jan-Ake
Inactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male mice.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(10):3857-62.
2005: Kong Eric H; Heldring Nina; Gustafsson Jan-Ake; Treuter Eckardt; Hubbard Roderick E; Pike Ashley C W
Delineation of a unique protein-protein interaction site on the surface of the estrogen receptor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(10):3593-8.
2005: Ohnemus Ulrich; Uenalan Murat; Conrad Franziska; Handjiski Bori; Mecklenburg Lars; Nakamura Motonobu; Inzunza José; Gustafsson Jan-Ake; Paus Ralf
Hair cycle control by estrogens: catagen induction via estrogen receptor (ER)-alpha is checked by ER beta signaling.
Endocrinology 2005;146(3):1214-25.
2005: Omoto Yoko; Lathe Richard; Warner Margaret; Gustafsson Jan-Ake
Early onset of puberty and early ovarian failure in CYP7B1 knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(8):2814-9.
2005: Omoto Yoko; Imamov Otabek; Warner Margaret; Gustafsson Jan-Ake
Estrogen receptor alpha and imprinting of the neonatal mouse ventral prostate by estrogen.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1484-9.
2005: Islander U; Erlandsson M C; Chavoshi T; Jochems C; Movérare S; Nilsson S; Ohlsson C; Gustafsson J-A; Carlsten H
Estren-mediated inhibition of T lymphopoiesis is estrogen receptor-independent whereas its suppression of T cell-mediated inflammation is estrogen receptor-dependent.
Clinical and experimental immunology 2005;139(2):210-5.
2005: Savolainen Saija; Santti Risto; Streng Tomi; Gustafsson Jan-Ake; Härkönen Pirkko; Mäkelä Sari
Sex specific expression of progesterone receptor in mouse lower urinary tract.
Molecular and cellular endocrinology 2005;230(1-2):17-21.
2005: Imwalle D Bradley; Gustafsson Jan-Ake; Rissman Emilie F
Lack of functional estrogen receptor beta influences anxiety behavior and serotonin content in female mice.
Physiology & behavior 2005;84(1):157-63.
2005: Cheng Guojun; Li Yan; Omoto Yoko; Wang Yanling; Berg Tove; Nord Magnus; Vihko Pirkko; Warner Margaret; Piao Yun-Shang; Gustafsson Jan-Ake
Differential regulation of estrogen receptor (ER)alpha and ERbeta in primate mammary gland.
The Journal of clinical endocrinology and metabolism 2005;90(1):435-44.
2005: Islander Ulrika; Hasséus Bengt; Erlandsson Malin C; Jochems Caroline; Skrtic Sofia Movérare; Lindberg Marie; Gustafsson Jan-Ake; Ohlsson Claes; Carlsten Hans
Estren promotes androgen phenotypes in primary lymphoid organs and submandibular glands.
BMC immunology 2005;6():16.
2005: Båvner Ann; Matthews Jason; Sanyal Sabyasachi; Gustafsson Jan-Ake; Treuter Eckardt
EID3 is a novel EID family member and an inhibitor of CBP-dependent co-activation.
Nucleic acids research 2005;33(11):3561-9.
2005: Nomura M; Akama K T; Alves S E; Korach K S; Gustafsson J-A; Pfaff D W; Ogawa S
Differential distribution of estrogen receptor (ER)-alpha and ER-beta in the midbrain raphe nuclei and periaqueductal gray in male mouse: Predominant role of ER-beta in midbrain serotonergic systems.
Neuroscience 2005;130(2):445-56.
2004: Imamov Otabek; Lopatkin Nikolay A; Gustafsson Jan-Ake
Estrogen receptor beta in prostate cancer.
The New England journal of medicine 2004;351(26):2773-4.
2004: Steffensen Knut R; Neo Soek Ying; Stulnig Thomas M; Vega Vinsensius B; Rahman Safia S; Schuster Gertrud U; Gustafsson Jan-Ake; Liu Edison T
Genome-wide expression profiling; a panel of mouse tissues discloses novel biological functions of liver X receptors in adrenals.
Journal of molecular endocrinology 2004;33(3):609-22.
2004: Vadlamudi Ratna K; Balasenthil Seetharaman; Broaddus Russell R; Gustafsson Jan-Ake; Kumar Rakesh
Deregulation of estrogen receptor coactivator proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor in human endometrial tumors.
The Journal of clinical endocrinology and metabolism 2004;89(12):6130-8.
2004: Anderson Steven P; Dunn Corrie; Laughter Ashley; Yoon Lawrence; Swanson Cynthia; Stulnig Thomas M; Steffensen Knut R; Chandraratna Roshantha A S; Gustafsson Jan-Ake; Corton J Christopher
Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor alpha, retinoid X receptor, and liver X receptor in mouse liver.
Molecular pharmacology 2004;66(6):1440-52.
2004: Leong Gary M; Moverare Sofia; Brce Jesena; Doyle Nathan; Sjögren Klara; Dahlman-Wright Karin; Gustafsson Jan-Ake; Ho Ken K Y; Ohlsson Claes; Leung Kin-Chuen
Estrogen up-regulates hepatic expression of suppressors of cytokine signaling-2 and -3 in vivo and in vitro.
Endocrinology 2004;145(12):5525-31.
2004: Glenmark Birgitta; Nilsson Maria; Gao Hui; Gustafsson Jan-Ake; Dahlman-Wright Karin; Westerblad Håkan
Difference in skeletal muscle function in males vs. females: role of estrogen receptor-beta.
American journal of physiology. Endocrinology and metabolism 2004;287(6):E1125-31.
2004: Fried G; Andersson E; Csöregh L; Enmark E; Gustafsson J-A; Aanesen A; Osterlund C
Estrogen receptor beta is expressed in human embryonic brain cells and is regulated by 17beta-estradiol.
The European journal of neuroscience 2004;20(9):2345-54.
2004: Gronemeyer Hinrich; Gustafsson Jan-Ake; Laudet Vincent
Principles for modulation of the nuclear receptor superfamily.
Nature reviews. Drug discovery 2004;3(11):950-64.
2004: Hartman Johan; Müller Patrick; Foster James S; Wimalasena Jay; Gustafsson Jan-Ake; Ström Anders
HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1.
Oncogene 2004;23(54):8826-33.
2004: Ulven Stine Marie; Dalen Knut Tomas; Gustafsson Jan-Ake; Nebb Hilde I
Tissue-specific autoregulation of the LXRalpha gene facilitates induction of apoE in mouse adipose tissue.
Journal of lipid research 2004;45(11):2052-62.
2004: Zhao Chunyan; Xu Li; Otsuki Michio; Toresson Gudrun; Koehler Konrad; Pan-Hammarström Qiang; Hammarström Lennart; Nilsson Stefan; Gustafsson Jan-Ake; Dahlman-Wright Karin
Identification of a functional variant of estrogen receptor beta in an African population.
Carcinogenesis 2004;25(11):2067-73.
2004: Berkenstam Anders; Färnegårdh Mathias; Gustafsson Jan-Ake
Convergence of lipid homeostasis through liver X and thyroid hormone receptors.
Mechanisms of ageing and development 2004;125(10-11):707-17.
2004: Corton J Christopher; Apte Udayan; Anderson Steven P; Limaye Pallavi; Yoon Lawrence; Latendresse John; Dunn Corrie; Everitt Jeffrey I; Voss Kenneth A; Swanson Cynthia; Kimbrough Carie; Wong Jean S; Gill Sarjeet S; Chandraratna Roshantha A S; Kwak Mi-Kyoung; Kensler Thomas W; Stulnig Thomas M; Steffensen Knut R; Gustafsson Jan-Ake; Mehendale Harihara M
Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors.
The Journal of biological chemistry 2004;279(44):46204-12.
2004: Kudwa Andrea E; Gustafsson Jan-Ake; Rissman Emilie F
Estrogen receptor beta modulates estradiol induction of progestin receptor immunoreactivity in male, but not in female, mouse medial preoptic area.
Endocrinology 2004;145(10):4500-6.
2004: Förster Carola; Kietz Silke; Hultenby Kjell; Warner Margaret; Gustafsson Jan-Ake
Characterization of the ERbeta-/-mouse heart.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(39):14234-9.
2004: Esslimani-Sahla Majida; Simony-Lafontaine Joelle; Kramar Andrew; Lavaill Roselyne; Mollevi Caroline; Warner Margaret; Gustafsson Jan-Ake; Rochefort Henri
Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(17):5769-76.
2004: Damdimopoulos Anastasios E; Miranda-Vizuete Antonio; Treuter Eckardt; Gustafsson Jan-Ake; Spyrou Giannis
An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling.
The Journal of biological chemistry 2004;279(37):38721-9.
2004: Shim Gil-Jin; Warner Margaret; Kim Hyun-Jin; Andersson Sandra; Liu Lining; Ekman Jenny; Imamov Otabek; Jones Margaret E; Simpson Evan R; Gustafsson Jan-Ake
Aromatase-deficient mice spontaneously develop a lymphoproliferative autoimmune disease resembling Sjogren's syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(34):12628-33.
2004: Palmieri C; Saji S; Sakaguchi H; Cheng G; Sunters A; O'Hare M J; Warner M; Gustafsson J-A; Coombes R C; Lam E W-F
The expression of oestrogen receptor (ER)-beta and its variants, but not ERalpha, in adult human mammary fibroblasts.
Journal of molecular endocrinology 2004;33(1):35-50.
2004: Jiménez Alberto; Zu Wei; Rawe Vanesa Y; Pelto-Huikko Markku; Flickinger Charles J; Sutovsky Peter; Gustafsson Jan-Ake; Oko Richard; Miranda-Vizuete Antonio
Spermatocyte/spermatid-specific thioredoxin-3, a novel Golgi apparatus-associated thioredoxin, is a specific marker of aberrant spermatogenesis.
The Journal of biological chemistry 2004;279(33):34971-82.
2004: Kietz Silke; Thomsen Jane S; Matthews Jason; Pettersson Katarina; Ström Anders; Gustafsson Jan-Ake
The Ah receptor inhibits estrogen-induced estrogen receptor beta in breast cancer cells.
Biochemical and biophysical research communications 2004;320(1):76-82.
2004: Lindgren Peter R; Cajander Stefan; Bäckström Torbjörn; Gustafsson Jan-Ake; Mäkelä Sari; Olofsson Jan I
Estrogen and progesterone receptors in ovarian epithelial tumors.
Molecular and cellular endocrinology 2004;221(1-2):97-104.
2004: Imamov Otabek; Morani Andrea; Shim Gil-Jin; Omoto Yoko; Thulin-Andersson Christina; Warner Margaret; Gustafsson Jan-Ake
Estrogen receptor beta regulates epithelial cellular differentiation in the mouse ventral prostate.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(25):9375-80.
2004: Lundholm L; Movérare S; Steffensen K R; Nilsson M; Otsuki M; Ohlsson C; Gustafsson J-A; Dahlman-Wright K
Gene expression profiling identifies liver X receptor alpha as an estrogen-regulated gene in mouse adipose tissue.
Journal of molecular endocrinology 2004;32(3):879-92.
2004: Polanczyk Magdalena; Yellayi Srikanth; Zamora Alex; Subramanian Sandhya; Tovey Micah; Vandenbark Arthur A; Offner Halina; Zachary James F; Fillmore Parley D; Blankenhorn Elizabeth P; Gustafsson Jan-Ake; Teuscher Cory
Estrogen receptor-1 (Esr1) and -2 (Esr2) regulate the severity of clinical experimental allergic encephalomyelitis in male mice.
The American journal of pathology 2004;164(6):1915-24.
2004: Toresson Gudrun; Schuster Gertrud U; Steffensen Knut R; Bengtsson Martin; Ljunggren Jan; Dahlman-Wright Karin; Gustafsson Jan-Ake
Purification of functional full-length liver X receptor beta produced in Escherichia coli.
Protein expression and purification 2004;35(2):190-8.
2004: Cabanes Anna; Wang Mingyue; Olivo Susan; DeAssis Sonia; Gustafsson Jan-Ake; Khan Galam; Hilakivi-Clarke Leena
Prepubertal estradiol and genistein exposures up-regulate BRCA1 mRNA and reduce mammary tumorigenesis.
Carcinogenesis 2004;25(5):741-8.
2004: Palmieri Carlo; Lam Eric W-F; Mansi Janine; MacDonald Claire; Shousha Sami; Madden Peter; Omoto Yoko; Sunters Andrew; Warner Margaret; Gustafsson Jan-Ake; Coombes R Charles
The expression of ER beta cx in human breast cancer and the relationship to endocrine therapy and survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2421-8.
2004: Heldring Nina; Nilsson Maria; Buehrer Benjamin; Treuter Eckardt; Gustafsson Jan-Ake
Identification of tamoxifen-induced coregulator interaction surfaces within the ligand-binding domain of estrogen receptors.
Molecular and cellular biology 2004;24(8):3445-59.
2004: Seo Jong Bae; Moon Hyang Mi; Kim Woo Sik; Lee Yun Sok; Jeong Hyun Woo; Yoo Eung Jae; Ham Jungyeob; Kang Heonjoong; Park Myoung-Gyu; Steffensen Knut R; Stulnig Thomas M; Gustafsson Jan-Ake; Park Sang Dai; Kim Jae Bum
Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression.
Molecular and cellular biology 2004;24(8):3430-44.
2004: Antonson Per; Al-Beidh Farah; Matthews Jason; Gustafsson Jan-Ake
The human RAP250 gene: genomic structure and promoter analysis.
Gene 2004;327(2):233-8.
2004: Cheng Guojun; Weihua Zhang; Warner Margaret; Gustafsson Jan-Ake
Estrogen receptors ER alpha and ER beta in proliferation in the rodent mammary gland.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(11):3739-46.
2004: Tujague Michel; Thomsen Jane S; Mizuki Kazuhito; Sadek Christine M; Gustafsson Jan-Ake
The focal adhesion protein vinexin alpha regulates the phosphorylation and activity of estrogen receptor alpha.
The Journal of biological chemistry 2004;279(10):9255-63.
2004: Steffensen Knut R; Gustafsson Jan-Ake
Putative metabolic effects of the liver X receptor (LXR).
Diabetes 2004;53 Suppl 1():S36-42.
2004: Ström Anders; Hartman Johan; Foster James S; Kietz Silke; Wimalasena Jay; Gustafsson Jan-Ake
Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(6):1566-71.
2004: Shim Gil-Jin; Kis Loránd Levente; Warner Margaret; Gustafsson Jan-Ake
Autoimmune glomerulonephritis with spontaneous formation of splenic germinal centers in mice lacking the estrogen receptor alpha gene.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(6):1720-4.
2004: Sanyal Sabyasachi; Matthews Jason; Bouton Didier; Kim Han-Jong; Choi Hueng-Sik; Treuter Eckardt; Gustafsson Jan-Ake
Deoxyribonucleic acid response element-dependent regulation of transcription by orphan nuclear receptor estrogen receptor-related receptor gamma.
Molecular endocrinology (Baltimore, Md.) 2004;18(2):312-25.
2004: Faulds Malin Hedengran; Olsen Hanne; Helguero Luisa A; Gustafsson Jan-Ake; Haldosén Lars-Arne
Estrogen receptor functional activity changes during differentiation of mammary epithelial cells.
Molecular endocrinology (Baltimore, Md.) 2004;18(2):412-21.
2004: Lassus Heini; Leminen Arto; Vayrynen Aki; Cheng Guojun; Gustafsson Jan-Ake; Isola Jorma; Butzow Ralf
ERBB2 amplification is superior to protein expression status in predicting patient outcome in serous ovarian carcinoma.
Gynecologic oncology 2004;92(1):31-9.
2004: Thomsen Jane Sohn; Kietz Silke; Ström Anders; Gustafsson Jan-Ake
HES-1, a novel target gene for the aryl hydrocarbon receptor.
Molecular pharmacology 2004;65(1):165-71.
2004: Välimaa H; Savolainen S; Soukka T; Silvoniemi P; Mäkelä S; Kujari H; Gustafsson J-A; Laine M
Estrogen receptor-beta is the predominant estrogen receptor subtype in human oral epithelium and salivary glands.
The Journal of endocrinology 2004;180(1):55-62.
2004: Nilsson M; Naessén S; Dahlman I; Lindén Hirschberg A; Gustafsson J-A; Dahlman-Wright K
Association of estrogen receptor beta gene polymorphisms with bulimic disease in women.
Molecular psychiatry 2004;9(1):28-34.
2004: Lin Chin-Yo; Ström Anders; Vega Vinsensius Berlian; Kong Say Li; Yeo Ai Li; Thomsen Jane S; Chan Wan Ching; Doray Balraj; Bangarusamy Dhinoth K; Ramasamy Adaikalavan; Vergara Liza A; Tang Suisheng; Chong Allen; Bajic Vladimir B; Miller Lance D; Gustafsson Jan-Ake; Liu Edison T
Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells.
Genome biology 2004;5(9):R66.
2004: Warner M; Gustafsson J A
How to understand estrogen signaling from the phenotypes of ERalpha and ERbeta knockout mice.
Ernst Schering Research Foundation workshop 2004;(46):63-77.
2004: Nilsson Maria; Dahlman-Wright Karin; Gustafsson Jan-Ake
Nuclear receptors in disease: the oestrogen receptors.
Essays in biochemistry 2004;40():157-67.
2004: Barkhem Tomas; Nilsson Stefan; Gustafsson Jan-Ake
Molecular mechanisms, physiological consequences and pharmacological implications of estrogen receptor action.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 2004;4(1):19-28.
2003: Steffensen Knut R; Holter Elin; Alikhani Nyosha; Eskild Winnie; Gustafsson Jan-Ake
Glucocorticoid response and promoter occupancy of the mouse LXRalpha gene.
Biochemical and biophysical research communications 2003;312(3):716-24.
2003: Movérare Sofia; Dahllund Johanna; Andersson Niklas; Islander Ulrika; Carlsten Hans; Gustafsson Jan-Ake; Nilsson Stefan; Ohlsson Claes
Estren is a selective estrogen receptor modulator with transcriptional activity.
Molecular pharmacology 2003;64(6):1428-33.
2003: Temple Jennifer L; Scordalakes Elka M; Bodo Cristian; Gustafsson Jan Ake; Rissman Emilie F
Lack of functional estrogen receptor beta gene disrupts pubertal male sexual behavior.
Hormones and behavior 2003;44(5):427-34.
2003: Patrone Cesare; Cassel Tobias N; Pettersson Katarina; Piao Yun-Shang; Cheng Guojun; Ciana Paolo; Maggi Adriana; Warner Margaret; Gustafsson Jan-Ake; Nord Magnus
Regulation of postnatal lung development and homeostasis by estrogen receptor beta.
Molecular and cellular biology 2003;23(23):8542-52.
2003: Movérare Sofia; Venken Katrien; Eriksson Anna-Lena; Andersson Niklas; Skrtic Stanko; Wergedal Jon; Mohan Subburaman; Salmon Phil; Bouillon Roger; Gustafsson Jan-Ake; Vanderschueren Dirk; Ohlsson Claes
Differential effects on bone of estrogen receptor alpha and androgen receptor activation in orchidectomized adult male mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13573-8.
2003: Dalen Knut Tomas; Ulven Stine Marie; Bamberg Krister; Gustafsson Jan-Ake; Nebb Hilde I
Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha.
The Journal of biological chemistry 2003;278(48):48283-91.
2003: Zhao Chunyan; Lam Eric W-F; Sunters Andrew; Enmark Eva; De Bella Manuela Tamburo; Coombes R Charles; Gustafsson Jan-Ake; Dahlman-Wright Karin
Expression of estrogen receptor beta isoforms in normal breast epithelial cells and breast cancer: regulation by methylation.
Oncogene 2003;22(48):7600-6.
2003: Mandelin Erik; Lassus Heini; Seppälä Markku; Leminen Arto; Gustafsson Jan-Ake; Cheng Guojun; Bützow Ralf; Koistinen Riitta
Glycodelin in ovarian serous carcinoma: association with differentiation and survival.
Cancer research 2003;63(19):6258-64.
2003: Steffensen Knut R; Nilsson Maria; Schuster Gertrud U; Stulnig Thomas M; Dahlman-Wright Karin; Gustafsson Jan-Ake
Gene expression profiling in adipose tissue indicates different transcriptional mechanisms of liver X receptors alpha and beta, respectively.
Biochemical and biophysical research communications 2003;310(2):589-93.
2003: Wärnmark Anette; Treuter Eckardt; Wright Anthony P H; Gustafsson Jan-Ake
Activation functions 1 and 2 of nuclear receptors: molecular strategies for transcriptional activation.
Molecular endocrinology (Baltimore, Md.) 2003;17(10):1901-9.
2003: Färnegårdh Mathias; Bonn Tomas; Sun Sherry; Ljunggren Jan; Ahola Harri; Wilhelmsson Anna; Gustafsson Jan-Ake; Carlquist Mats
The three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands.
The Journal of biological chemistry 2003;278(40):38821-8.
2003: Gustafsson Jan-Ake
What pharmacologists can learn from recent advances in estrogen signalling.
Trends in pharmacological sciences 2003;24(9):479-85.
2003: Islander U; Erlandsson M C; Hasséus B; Jonsson C A; Ohlsson C; Gustafsson J-A; Dahlgren U; Carlsten H
Influence of oestrogen receptor alpha and beta on the immune system in aged female mice.
Immunology 2003;110(1):149-57.
2003: Garey J; Goodwillie A; Frohlich J; Morgan M; Gustafsson J-A; Smithies O; Korach K S; Ogawa S; Pfaff D W
Genetic contributions to generalized arousal of brain and behavior.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):11019-22.
2003: Schröder Annette; Pandita Raj K; Hedlund Petter; Warner Margret; Gustafsson Jan-Ake; Andersson Karl-Erik
Estrogen receptor subtypes and afferent signaling in the bladder.
The Journal of urology 2003;170(3):1013-6.
2003: Otsuki Michio; Gao Hui; Dahlman-Wright Karin; Ohlsson Claes; Eguchi Naomi; Urade Yoshihiro; Gustafsson Jan-Ake
Specific regulation of lipocalin-type prostaglandin D synthase in mouse heart by estrogen receptor beta.
Molecular endocrinology (Baltimore, Md.) 2003;17(9):1844-55.
2003: Matthews Jason; Gustafsson Jan-Ake
Estrogen signaling: a subtle balance between ER alpha and ER beta.
Molecular interventions 2003;3(5):281-92.
2003: Xu Li; Pan-Hammarström Qiang; Försti Asta; Hemminki Kari; Hammarström Lennart; Labuda Damian; Gustafsson Jan-Ake; Dahlman-Wright Karin
Human estrogen receptor beta 548 is not a common variant in three distinct populations.
Endocrinology 2003;144(8):3541-6.
2003: Weihua Zhang; Andersson Sandra; Cheng Guojun; Simpson Evan R; Warner Margaret; Gustafsson Jan-Ake
Update on estrogen signaling.
FEBS letters 2003;546(1):17-24.
2003: Bajic Vladimir B; Tan Sin Lam; Chong Allen; Tang Suisheng; Ström Anders; Gustafsson Jan-Ake; Lin Chin-Yo; Liu Edison T
Dragon ERE Finder version 2: A tool for accurate detection and analysis of estrogen response elements in vertebrate genomes.
Nucleic acids research 2003;31(13):3605-7.
2003: Widén Christina; Gustafsson Jan-Ake; Wikström Ann-Charlotte
Cytosolic glucocorticoid receptor interaction with nuclear factor-kappa B proteins in rat liver cells.
The Biochemical journal 2003;373(Pt 1):211-20.
2003: Försti Asta; Zhao Chunyan; Israelsson Elisabeth; Dahlman-Wright Karin; Gustafsson Jan-Ake; Hemminki Kari
Polymorphisms in the estrogen receptor beta gene and risk of breast cancer: no association.
Breast cancer research and treatment 2003;79(3):409-13.
2003: Tazawa Hiroshi; Osman Waffa; Shoji Yutaka; Treuter Eckardt; Gustafsson Jan-Ake; Zilliacus Johanna
Regulation of subnuclear localization is associated with a mechanism for nuclear receptor corepression by RIP140.
Molecular and cellular biology 2003;23(12):4187-98.
2003: Kauppi Björn; Jakob Clarissa; Färnegårdh Mathias; Yang Jie; Ahola Harri; Alarcon Maria; Calles Karin; Engström Owe; Harlan John; Muchmore Steven; Ramqvist Anna-Karin; Thorell Susanne; Ohman Lars; Greer Jonathan; Gustafsson Jan-Ake; Carlstedt-Duke Jan; Carlquist Mats
The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism.
The Journal of biological chemistry 2003;278(25):22748-54.
2003: Bennett Haley L; Gustafsson Jan Ake; Keast Janet R
Estrogen receptor expression in lumbosacral dorsal root ganglion cells innervating the female rat urinary bladder.
Autonomic neuroscience : basic & clinical 2003;105(2):90-100.
2003: Shim Gil-Jin; Wang Ling; Andersson Sandra; Nagy Noémi; Kis Loránd Levente; Zhang Qinghong; Mäkelä Sari; Warner Margaret; Gustafsson Jan-Ake
Disruption of the estrogen receptor beta gene in mice causes myeloproliferative disease resembling chronic myeloid leukemia with lymphoid blast crisis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(11):6694-9.
2003: Choleris Elena; Gustafsson Jan-Ake; Korach Kenneth S; Muglia Louis J; Pfaff Donald W; Ogawa Sonoko
An estrogen-dependent four-gene micronet regulating social recognition: a study with oxytocin and estrogen receptor-alpha and -beta knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):6192-7.
2003: Sadek C M; Pelto-Huikko M; Tujague M; Steffensen K R; Wennerholm M; Gustafsson J-A
TACC3 expression is tightly regulated during early differentiation.
Gene expression patterns : GEP 2003;3(2):203-11.
2003: Aitola Marjo; Sadek Christine M; Gustafsson Jan-Ake; Pelto-Huikko Markku
Aint/Tacc3 is highly expressed in proliferating mouse tissues during development, spermatogenesis, and oogenesis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003;51(4):455-69.
2003: Sadek Christine M; Jiménez Alberto; Damdimopoulos Anastasios E; Kieselbach Thomas; Nord Magnus; Gustafsson Jan-Ake; Spyrou Giannis; Davis Elaine C; Oko Richard; van der Hoorn Frans A; Miranda-Vizuete Antonio
Characterization of human thioredoxin-like 2. A novel microtubule-binding thioredoxin expressed predominantly in the cilia of lung airway epithelium and spermatid manchette and axoneme.
The Journal of biological chemistry 2003;278(15):13133-42.
2003: Micevych Paul E; Rissman Emilie F; Gustafsson Jan-Ake; Sinchak Kevin
Estrogen receptor-alpha is required for estrogen-induced mu-opioid receptor internalization.
Journal of neuroscience research 2003;71(6):802-10.
2003: Antonson Per; Schuster Gertrud U; Wang Ling; Rozell Björn; Holter Elin; Flodby Per; Treuter Eckardt; Holmgren Lars; Gustafsson Jan-Ake
Inactivation of the nuclear receptor coactivator RAP250 in mice results in placental vascular dysfunction.
Molecular and cellular biology 2003;23(4):1260-8.
2003: Lindberg Marie K; Movérare Sofia; Skrtic Stanko; Gao Hui; Dahlman-Wright Karin; Gustafsson Jan-Ake; Ohlsson Claes
Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice.
Molecular endocrinology (Baltimore, Md.) 2003;17(2):203-8.
2003: Juvet Lene K; Andresen Sissel M; Schuster Gertrud U; Dalen Knut Tomas; Tobin Kari Anne R; Hollung Kristin; Haugen Fred; Jacinto Severina; Ulven Stine M; Bamberg Krister; Gustafsson Jan-Ake; Nebb Hilde I
On the role of liver X receptors in lipid accumulation in adipocytes.
Molecular endocrinology (Baltimore, Md.) 2003;17(2):172-82.
2003: Wang Ling; Andersson Sandra; Warner Margaret; Gustafsson Jan-Ake
Estrogen receptor (ER)beta knockout mice reveal a role for ERbeta in migration of cortical neurons in the developing brain.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(2):703-8.
2003: Ogawa Sonoko; Chan Johnny; Gustafsson Jan-Ake; Korach Kenneth S; Pfaff Donald W
Estrogen increases locomotor activity in mice through estrogen receptor alpha: specificity for the type of activity.
Endocrinology 2003;144(1):230-9.
2003: Cunnea Paula M; Miranda-Vizuete Antonio; Bertoli Gloria; Simmen Thomas; Damdimopoulos Anastasios E; Hermann Stefan; Leinonen Saku; Huikko Markku Pelto; Gustafsson Jan-Ake; Sitia Roberto; Spyrou Giannis
ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress.
The Journal of biological chemistry 2003;278(2):1059-66.
2003: Otsuki Michio; Dahlman-Wright Karin; Gustafsson Jan-Ake
Cardiovascular roles of estrogen receptors: insights gained from knockout models.
Nuclear receptor signaling 2003;1():e003.
2003: Warner Margaret; Wang Ling; Weihua Zhang; Cheng Guojun; Sakaguchi Hideki; Saji Shigehira; Nilsson Stefan; Kiesselbach Thomas; Gustafsson Jan-Ake
Analysis of estrogen receptor expression in tissues.
Methods in enzymology 2003;364():448-63.
2002: Lindberg Marie K; Movérare Sofia; Eriksson Anna-Lena; Skrtic Stanko; Gao Hui; Dahlman-Wright Karin; Gustafsson Jan-Ake; Ohlsson Claes
Identification of estrogen-regulated genes of potential importance for the regulation of trabecular bone mineral density.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(12):2183-95.
2002: Stulnig Thomas M; Steffensen Knut R; Gao Hui; Reimers Mark; Dahlman-Wright Karin; Schuster Gertrud U; Gustafsson Jan-Ake
Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue.
Molecular pharmacology 2002;62(6):1299-305.
2002: Borgius Lotta Johansson; Steffensen Knut R; Gustafsson Jan-Ake; Treuter Eckardt
Glucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHP.
The Journal of biological chemistry 2002;277(51):49761-6.
2002: Movérare Sofia; Lindberg Marie K; Faergemann Jan; Gustafsson J-A; Ohlsson Claes
Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the hair follicle cycling as well as the thickness of epidermis in male mice.
The Journal of investigative dermatology 2002;119(5):1053-8.
2002: Förster Carola; Mäkela Sari; Wärri Anni; Kietz Silke; Becker David; Hultenby Kjell; Warner Margaret; Gustafsson Jan-Ake
Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15578-83.
2002: Barkhem Tomas; Haldosén Lars-Arne; Gustafsson Jan-Ake; Nilsson Stefan
Transcriptional synergism on the pS2 gene promoter between a p160 coactivator and estrogen receptor-alpha depends on the coactivator subtype, the type of estrogen response element, and the promoter context.
Molecular endocrinology (Baltimore, Md.) 2002;16(11):2571-81.
2002: Cheng Guojun; Imamov Otabek; Omoto Yoko; Warner Margaret; Gustafsson Jan-Ake
What is the value of measuring MTA-1s in breast cancer?
Molecular interventions 2002;2(6):360-2, 338.
2002: Jiménez Alberto; Johansson Catrine; Ljung Johanna; Sagemark Johan; Berndt Kurt D; Ren Bin; Tibbelin Gudrun; Ladenstein Rudolf; Kieselbach Thomas; Holmgren Arne; Gustafsson Jan Ake; Miranda-Vizuete Antonio
Human spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity.
FEBS letters 2002;530(1-3):79-84.
2002: Weihua Zhang; Lathe Richard; Warner Margaret; Gustafsson Jan-Ake
An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13589-94.
2002: Wang Ling; Schuster Gertrud U; Hultenby Kjell; Zhang Qinghong; Andersson Sandra; Gustafsson Jan-Ake
Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13878-83.
2002: Saji Shigehira; Omoto Yoko; Shimizu Chikako; Warner Margaret; Hayashi Yukiko; Horiguchi Shin-ichiro; Watanabe Toru; Hayashi Shin-ichi; Gustafsson Jan-Ake; Toi Masakazu
Expression of estrogen receptor (ER) (beta)cx protein in ER(alpha)-positive breast cancer: specific correlation with progesterone receptor.
Cancer research 2002;62(17):4849-53.
2002: Damdimopoulos Anastasios E; Miranda-Vizuete Antonio; Pelto-Huikko Markku; Gustafsson Jan-Ake; Spyrou Giannis
Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death.
The Journal of biological chemistry 2002;277(36):33249-57.
2002: Schuster Gertrud U; Parini Paolo; Wang Ling; Alberti Siegfried; Steffensen Knut R; Hansson Göran K; Angelin Bo; Gustafsson Jan-Ake
Accumulation of foam cells in liver X receptor-deficient mice.
Circulation 2002;106(9):1147-53.
2002: Lindberg M K; Weihua Z; Andersson N; Movérare S; Gao H; Vidal O; Erlandsson M; Windahl S; Andersson G; Lubahn D B; Carlsten H; Dahlman-Wright K; Gustafsson J-A; Ohlsson C
Estrogen receptor specificity for the effects of estrogen in ovariectomized mice.
The Journal of endocrinology 2002;174(2):167-78.
2002: Jiménez Alberto; Oko Richard; Gustafsson Jan-Ake; Spyrou Giannis; Pelto-Huikko Markku; Miranda-Vizuete Antonio
Cloning, expression and characterization of mouse spermatid specific thioredoxin-1 gene and protein.
Molecular human reproduction 2002;8(8):710-8.
2002: Stulnig Thomas M; Oppermann Udo; Steffensen Knut R; Schuster Gertrud U; Gustafsson Jan-Ake
Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity.
Diabetes 2002;51(8):2426-33.
2002: Weihua Zhang; Ekman Jenny; Almkvist Asa; Saji Shigehira; Wang Ling; Warner Margaret; Gustafsson Jan-Ake
Involvement of androgen receptor in 17beta-estradiol-induced cell proliferation in rat uterus.
Biology of reproduction 2002;67(2):616-23.
2002: Muller Patrick; Kietz Silke; Gustafsson Jan-Ake; Strom Anders
The anti-estrogenic effect of all-trans-retinoic acid on the breast cancer cell line MCF-7 is dependent on HES-1 expression.
The Journal of biological chemistry 2002;277(32):28376-9.
2002: Windahl Sara H; Andersson Göran; Gustafsson Jan-Ake
Elucidation of estrogen receptor function in bone with the use of mouse models.
Trends in endocrinology and metabolism: TEM 2002;13(5):195-200.
2002: Weihua Zhang; Warner Margaret; Gustafsson Jan-Ake
Estrogen receptor beta in the prostate.
Molecular and cellular endocrinology 2002;193(1-2):1-5.
2002: Helander Hanna; Gustafsson Jan-Ake; Mode Agneta
Possible involvement of truncated signal transducer and activator of transcription-5 in the GH pattern-dependent regulation of CYP2C12 gene expression in rat liver.
Molecular endocrinology (Baltimore, Md.) 2002;16(7):1598-611.
2002: Wang Ling; Andersson Sandra; Warner Margaret; Gustafsson Jan-Ake
Estrogen actions in the brain.
Science's STKE : signal transduction knowledge environment 2002;2002(138):pe29.
2002: Matsuyama Satoru; Ohkura Yasuo; Eguchi Hidetaka; Kobayashi Yasuhito; Akagi Kiwamu; Uchida Kenji; Nakachi Kei; Gustafsson Jan-Ake; Hayashi Shin-Ichi
Estrogen receptor beta is expressed in human stomach adenocarcinoma.
Journal of cancer research and clinical oncology 2002;128(6):319-24.
2002: Barkhem Tomas; Haldosén Lars-Arne; Gustafsson Jan-Ake; Nilsson Stefan
pS2 Gene expression in HepG2 cells: complex regulation through crosstalk between the estrogen receptor alpha, an estrogen-responsive element, and the activator protein 1 response element.
Molecular pharmacology 2002;61(6):1273-83.
2002: Wärnmark Anette; Treuter Eckardt; Gustafsson Jan-Ake; Hubbard Roderick E; Brzozowski Andrzej M; Pike Ashley C W
Interaction of transcriptional intermediary factor 2 nuclear receptor box peptides with the coactivator binding site of estrogen receptor alpha.
The Journal of biological chemistry 2002;277(24):21862-8.
2002: Steffensen Knut R; Schuster Gertrud U; Parini Paolo; Holter Elin; Sadek Christine M; Cassel Tobias; Eskild Winnie; Gustafsson Jan-Ake
Different regulation of the LXRalpha promoter activity by isoforms of CCAAT/enhancer-binding proteins.
Biochemical and biophysical research communications 2002;293(5):1333-40.
2002: Nomura Masayoshi; Durbak Larissa; Chan Johnny; Smithies Oliver; Gustafsson Jan-Ake; Korach Kenneth S; Pfaff Donald W; Ogawa Sonoko
Genotype/age interactions on aggressive behavior in gonadally intact estrogen receptor beta knockout (betaERKO) male mice.
Hormones and behavior 2002;41(3):288-96.
2002: Båvner Ann; Johansson Lotta; Toresson Gudrun; Gustafsson Jan-Ake; Treuter Eckardt
A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP.
EMBO reports 2002;3(5):478-84.
2002: Lindberg Marie K; Movérare Sofia; Skrtic Stanko; Alatalo Sari; Halleen Jussi; Mohan Subburaman; Gustafsson J A; Ohlsson Claes
Two different pathways for the maintenance of trabecular bone in adult male mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(4):555-62.
2002: Pepe Gerald J; Billiar Reinhart B; Leavitt Maria G; Zachos Nicholas C; Gustafsson Jan Ake; Albrecht Eugene D
Expression of estrogen receptors alpha and beta in the baboon fetal ovary.
Biology of reproduction 2002;66(4):1054-60.
2002: Enmark Eva; Gustafsson Jan Ake
[Nuclear receptors in man, fly and worm provide greater understanding of disease]
Läkartidningen 2002;99(11):1186-90.
2002: Palmieri C; Cheng G J; Saji S; Zelada-Hedman M; Wärri A; Weihua Z; Van Noorden S; Wahlstrom T; Coombes R C; Warner M; Gustafsson J-A
Estrogen receptor beta in breast cancer.
Endocrine-related cancer 2002;9(1):1-13.
2002: Rissman Emilie F; Heck Amy L; Leonard Julie E; Shupnik Margaret A; Gustafsson Jan-Ake
Disruption of estrogen receptor beta gene impairs spatial learning in female mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3996-4001.
2002: Holter Elin; Kotaja Noora; Mäkela Sari; Strauss Leena; Kietz Silke; Jänne Olli A; Gustafsson Jan-Ake; Palvimo Jorma J; Treuter Eckardt
Inhibition of androgen receptor (AR) function by the reproductive orphan nuclear receptor DAX-1.
Molecular endocrinology (Baltimore, Md.) 2002;16(3):515-28.
2002: Tobin Kari Anne Risan; Ulven Stine M; Schuster Gertrud U; Steineger Hilde Hermansen; Andresen Sissel Mahle; Gustafsson Jan-Ake; Nebb Hilde Irene
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis.
The Journal of biological chemistry 2002;277(12):10691-7.
2002: Ciana Paolo; Vegeto Elisabetta; Beato Miguel; Chambon Pierre; Gustafsson Jan-Ake; Parker Malcolm; Wahli Walter; Maggi Adriana
Looking at nuclear receptors from the heights of Erice. Workshop on nuclear receptor structure and function.
EMBO reports 2002;3(2):125-9.
2002: Zhu Yan; Bian Zhao; Lu Ping; Karas Richard H; Bao Lin; Cox Daniel; Hodgin Jeffrey; Shaul Philip W; Thoren Peter; Smithies Oliver; Gustafsson Jan-Ake; Mendelsohn Michael E
Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta.
Science (New York, N.Y.) 2002;295(5554):505-8.
2002: Cheng Guojun; Weihua Zhang; Mäkinen Sirpa; Mäkelä Sari; Saji Shigehira; Warner Margaret; Gustafsson Jan-Ake; Hovatta Outi
A role for the androgen receptor in follicular atresia of estrogen receptor beta knockout mouse ovary.
Biology of reproduction 2002;66(1):77-84.
2002: Nilsson Stefan; Gustafsson Jan-Ake
Estrogen receptor action.
Critical reviews in eukaryotic gene expression 2002;12(4):237-57.
2002: Saji Shigehira; Omoto Yoko; Shimizu Chikako; Horiguchi Shin-ichiro; Watanabe Toru; Funata Nobuaki; Hayash Shin-ichi; Gustafsson Jan-Ake; Toi Masakazu
Clinical impact of assay of estrogen receptor beta cx in breast cancer.
Breast cancer (Tokyo, Japan) 2002;9(4):303-7.
2002: Nilsson Stefan; Gustafsson Jan-Ake
Biological role of estrogen and estrogen receptors.
Critical reviews in biochemistry and molecular biology 2002;37(1):1-28.
2001: Steffensen K R; Holter E; Tobin K A; Leclerc S; Gustafsson J A; Guérin S L; Eskild W
Members of the nuclear factor 1 family reduce the transcriptional potential of the nuclear receptor LXRalpha promoter.
Biochemical and biophysical research communications 2001;289(5):1262-7.
2001: Lindberg M K; Erlandsson M; Alatalo S L; Windahl S; Andersson G; Halleen J M; Carlsten H; Gustafsson J A; Ohlsson C
Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the OPG/RANKL (osteoprotegerin/receptor activator of NF-kappa B ligand) ratio and serum interleukin-6 in male mice.
The Journal of endocrinology 2001;171(3):425-33.
2001: Sadek C M; Damdimopoulos A E; Pelto-Huikko M; Gustafsson J A; Spyrou G; Miranda-Vizuete A
Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(12):1077-90.
2001: Jensen E V; Cheng G; Palmieri C; Saji S; Mäkelä S; Van Noorden S; Wahlström T; Warner M; Coombes R C; Gustafsson J A
Estrogen receptors and proliferation markers in primary and recurrent breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15197-202.
2001: Wärnmark A; Wikström A; Wright A P; Gustafsson J A; Härd T
The N-terminal regions of estrogen receptor alpha and beta are unstructured in vitro and show different TBP binding properties.
The Journal of biological chemistry 2001;276(49):45939-44.
2001: Lindberg M K; Alatalo S L; Halleen J M; Mohan S; Gustafsson J A; Ohlsson C
Estrogen receptor specificity in the regulation of the skeleton in female mice.
The Journal of endocrinology 2001;171(2):229-36.
2001: Faulds M H; Pettersson K; Gustafsson J A; Haldosén L A
Cross-talk between ERs and signal transducer and activator of transcription 5 is E2 dependent and involves two functionally separate mechanisms.
Molecular endocrinology (Baltimore, Md.) 2001;15(11):1929-40.
2001: Nilsson S; Mäkelä S; Treuter E; Tujague M; Thomsen J; Andersson G; Enmark E; Pettersson K; Warner M; Gustafsson J A
Mechanisms of estrogen action.
Physiological reviews 2001;81(4):1535-65.
2001: Windahl S H; Hollberg K; Vidal O; Gustafsson J A; Ohlsson C; Andersson G
Female estrogen receptor beta-/- mice are partially protected against age-related trabecular bone loss.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(8):1388-98.
2001: Salmi S; Santti R; Gustafsson J A; Mäkelä S
Co-localization of androgen receptor with estrogen receptor beta in the lower urinary tract of the male rat.
The Journal of urology 2001;166(2):674-7.
2001: Miranda-Vizuete A; Ljung J; Damdimopoulos A E; Gustafsson J A; Oko R; Pelto-Huikko M; Spyrou G
Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa.
The Journal of biological chemistry 2001;276(34):31567-74.
2001: Bian Z; Nilsson S; Gustafsson J A
Selective estrogen receptor modulators and coronary heart disease.
Trends in cardiovascular medicine 2001;11(5):196-202.
2001: Wärnmark A; Almlöf T; Leers J; Gustafsson J A; Treuter E
Differential recruitment of the mammalian mediator subunit TRAP220 by estrogen receptors ERalpha and ERbeta.
The Journal of biological chemistry 2001;276(26):23397-404.
2001: Erlandsson M C; Ohlsson C; Gustafsson J A; Carlsten H
Role of oestrogen receptors alpha and beta in immune organ development and in oestrogen-mediated effects on thymus.
Immunology 2001;103(1):17-25.
2001: Weihua Z; Makela S; Andersson L C; Salmi S; Saji S; Webster J I; Jensen E V; Nilsson S; Warner M; Gustafsson J A
A role for estrogen receptor beta in the regulation of growth of the ventral prostate.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6330-5.
2001: Doppler W; Windegger M; Soratroi C; Tomasi J; Lechner J; Rusconi S; Cato A C; Almlöf T; Liden J; Okret S; Gustafsson J A; Richard-Foy H; Starr D B; Klocker H; Edwards D; Geymayer S
Expression level-dependent contribution of glucocorticoid receptor domains for functional interaction with STAT5.
Molecular and cellular biology 2001;21(9):3266-79.
2001: Zilliacus J; Holter E; Wakui H; Tazawa H; Treuter E; Gustafsson J A
Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140.
Molecular endocrinology (Baltimore, Md.) 2001;15(4):501-11.
2001: Alberti S; Schuster G; Parini P; Feltkamp D; Diczfalusy U; Rudling M; Angelin B; Björkhem I; Pettersson S; Gustafsson J A
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice.
The Journal of clinical investigation 2001;107(5):565-73.
2001: Pike A C; Brzozowski A M; Walton J; Hubbard R E; Thorsell A G; Li Y L; Gustafsson J A; Carlquist M
Structural insights into the mode of action of a pure antiestrogen.
Structure (London, England : 1993) 2001;9(2):145-53.
2001: Wang L; Andersson S; Warner M; Gustafsson J A
Morphological abnormalities in the brains of estrogen receptor beta knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2792-6.
2001: Flodby P; Teglund S; Gustafsson J A
Knockout mice and steroid receptor research.
Methods in molecular biology (Clifton, N.J.) 2001;176():201-26.
2000: Mäkelä S; Strauss L; Kuiper G; Valve E; Salmi S; Santti R; Gustafsson J A
Differential expression of estrogen receptors alpha and beta in adult rat accessory sex glands and lower urinary tract.
Molecular and cellular endocrinology 2000;170(1-2):219-29.
2000: Ogawa S; Chester A E; Hewitt S C; Walker V R; Gustafsson J A; Smithies O; Korach K S; Pfaff D W
Abolition of male sexual behaviors in mice lacking estrogen receptors alpha and beta (alpha beta ERKO).
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14737-41.
2000: Zhang H; Thomsen J S; Johansson L; Gustafsson J A; Treuter E
DAX-1 functions as an LXXLL-containing corepressor for activated estrogen receptors.
The Journal of biological chemistry 2000;275(51):39855-9.
2000: Widén C; Zilliacus J; Gustafsson J A; Wikström A C
Glucocorticoid receptor interaction with 14-3-3 and Raf-1, a proposed mechanism for cross-talk of two signal transduction pathways.
The Journal of biological chemistry 2000;275(50):39296-301.
2000: Mikitani K; Sugasaki T; Shimada T; Kobayashi M; Gustafsson J A
The chitinase gene of the silkworm, Bombyx mori, contains a novel Tc-like transposable element.
The Journal of biological chemistry 2000;275(48):37725-32.
2000: Gustafsson J A; Warner M
Estrogen receptor beta in the breast: role in estrogen responsiveness and development of breast cancer.
The Journal of steroid biochemistry and molecular biology 2000;74(5):245-8.
2000: Ström A; Arai N; Leers J; Gustafsson J A
The Hairy and Enhancer of Split homologue-1 (HES-1) mediates the proliferative effect of 17beta-estradiol on breast cancer cell lines.
Oncogene 2000;19(51):5951-3.
2000: Ohlsson C; Hellberg N; Parini P; Vidal O; Bohlooly-Y M; Rudling M; Lindberg M K; Warner M; Angelin B; Gustafsson J A
Obesity and disturbed lipoprotein profile in estrogen receptor-alpha-deficient male mice.
Biochemical and biophysical research communications 2000;278(3):640-5.
2000: Spong C Y; McCune S K; Sternberg E M; Gustafsson J A
Maternal estrogen receptor-beta expression during mouse gestation.
American journal of reproductive immunology (New York, N.Y. : 1989) 2000;44(4):249-52.
2000: Pettersson K; Delaunay F; Gustafsson J A
Estrogen receptor beta acts as a dominant regulator of estrogen signaling.
Oncogene 2000;19(43):4970-8.
2000: Sadek C M; Jalaguier S; Feeney E P; Aitola M; Damdimopoulos A E; Pelto-Huikko M; Gustafsson J A
Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic development.
Mechanisms of development 2000;97(1-2):13-26.
2000: Cabanes A; de Assis S; Gustafsson J A; Hilakivi-Clarke L
Maternal high n-6 polyunsaturated fatty acid intake during pregnancy increases voluntary alcohol intake and hypothalamic estrogen receptor alpha and beta levels among female offspring.
Developmental neuroscience 2000;22(5-6):488-93.
2000: Hubbard R E; Pike A C; Brzozowski A M; Walton J; Bonn T; Gustafsson J A; Carlquist M
Structural insights into the mechanisms of agonism and antagonism in oestrogen receptor isoforms.
European journal of cancer (Oxford, England : 1990) 2000;36 Suppl 4():S17-8.
2000: Gustafsson J A
New insights in oestrogen receptor (ER) research - the ERbeta.
European journal of cancer (Oxford, England : 1990) 2000;36 Suppl 4():S16.
2000: Delaunay F; Pettersson K; Tujague M; Gustafsson J A
Functional differences between the amino-terminal domains of estrogen receptors alpha and beta.
Molecular pharmacology 2000;58(3):584-90.
2000: Takahashi S; Wakui H; Gustafsson J A; Zilliacus J; Itoh H
Functional interaction of the immunosuppressant mizoribine with the 14-3-3 protein.
Biochemical and biophysical research communications 2000;274(1):87-92.
2000: Liden J; Rafter I; Truss M; Gustafsson J A; Okret S
Glucocorticoid effects on NF-kappaB binding in the transcription of the ICAM-1 gene.
Biochemical and biophysical research communications 2000;273(3):1008-14.
2000: Mäkelä S; Strauss L; Kuiper G; Valve E; Salmi S; Santti R; Gustafsson J A
Differential expression of estrogen receptors alpha and beta in adult rat accessory sex glands and lower urinary tract.
Molecular and cellular endocrinology 2000;164(1-2):109-16.
2000: Weihua Z; Saji S; Mäkinen S; Cheng G; Jensen E V; Warner M; Gustafsson J A
Estrogen receptor (ER) beta, a modulator of ERalpha in the uterus.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):5936-41.
2000: Pedrajas J R; Miranda-Vizuete A; Javanmardy N; Gustafsson J A; Spyrou G
Mitochondria of Saccharomyces cerevisiae contain one-conserved cysteine type peroxiredoxin with thioredoxin peroxidase activity.
The Journal of biological chemistry 2000;275(21):16296-301.
2000: Tobin K A; Steineger H H; Alberti S; Spydevold O; Auwerx J; Gustafsson J A; Nebb H I
Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha.
Molecular endocrinology (Baltimore, Md.) 2000;14(5):741-52.
2000: Vidal O; Lindberg M K; Hollberg K; Baylink D J; Andersson G; Lubahn D B; Mohan S; Gustafsson J A; Ohlsson C
Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5474-9.
2000: Patrone C; Pollio G; Vegeto E; Enmark E; de Curtis I; Gustafsson J A; Maggi A
Estradiol induces differential neuronal phenotypes by activating estrogen receptor alpha or beta.
Endocrinology 2000;141(5):1839-45.
2000: Rybnikova E; Damdimopoulos A E; Gustafsson J A; Spyrou G; Pelto-Huikko M
Expression of novel antioxidant thioredoxin-2 in the rat brain.
The European journal of neuroscience 2000;12(5):1669-78.
2000: Wärnmark A; Gustafsson J A; Wright A P
Architectural principles for the structure and function of the glucocorticoid receptor tau 1 core activation domain.
The Journal of biological chemistry 2000;275(20):15014-8.
2000: Arai N; Ström A; Rafter J J; Gustafsson J A
Estrogen receptor beta mRNA in colon cancer cells: growth effects of estrogen and genistein.
Biochemical and biophysical research communications 2000;270(2):425-31.
2000: Cassel T N; Nordlund-Möller L; Andersson O; Gustafsson J A; Nord M
C/EBPalpha and C/EBPdelta activate the clara cell secretory protein gene through interaction with two adjacent C/EBP-binding sites.
American journal of respiratory cell and molecular biology 2000;22(4):469-80.
2000: Enmark E; Gustafsson J A
Nematode genome sequence dramatically extends the nuclear receptor superfamily.
Trends in pharmacological sciences 2000;21(3):85-7.
2000: Wallberg A E; Neely K E; Hassan A H; Gustafsson J A; Workman J L; Wright A P
Recruitment of the SWI-SNF chromatin remodeling complex as a mechanism of gene activation by the glucocorticoid receptor tau1 activation domain.
Molecular and cellular biology 2000;20(6):2004-13.
2000: Saville B; Wormke M; Wang F; Nguyen T; Enmark E; Kuiper G; Gustafsson J A; Safe S
Ligand-, cell-, and estrogen receptor subtype (alpha/beta)-dependent activation at GC-rich (Sp1) promoter elements.
The Journal of biological chemistry 2000;275(8):5379-87.
2000: Caira F; Antonson P; Pelto-Huikko M; Treuter E; Gustafsson J A
Cloning and characterization of RAP250, a novel nuclear receptor coactivator.
The Journal of biological chemistry 2000;275(8):5308-17.
2000: Windahl S H; Norgård M; Kuiper G G; Gustafsson J A; Andersson G
Cellular distribution of estrogen receptor beta in neonatal rat bone.
Bone 2000;26(2):117-21.
2000: Alberti S; Steffensen K R; Gustafsson J A
Structural characterisation of the mouse nuclear oxysterol receptor genes LXRalpha and LXRbeta.
Gene 2000;243(1-2):93-103.
2000: Johansson L; Båvner A; Thomsen J S; Färnegårdh M; Gustafsson J A; Treuter E
The orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptors.
Molecular and cellular biology 2000;20(4):1124-33.
2000: Cassel T N; Gustafsson J A; Nord M
CYP2B1 is regulated by C/EBP alpha and C/EBP delta inlung epithelial cells.
Molecular cell biology research communications : MCBRC 2000;3(1):42-7.
2000: Saji S; Jensen E V; Nilsson S; Rylander T; Warner M; Gustafsson J A
Estrogen receptors alpha and beta in the rodent mammary gland.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):337-42.
2000: Wallberg A E; Wright A; Gustafsson J A
Chromatin-remodeling complexes involved in gene activation by the glucocorticoid receptor.
Vitamins and hormones 2000;60():75-122.
2000: Treuter E; Warner M; Gustafsson J A
Mechanism of oestrogen signalling with particular reference to the role of ER beta in the central nervous system.
Novartis Foundation symposium 2000;230():7-14; discussion 15-9.
2000: Wallberg A E; Flinn E M; Gustafsson J A; Wright A P
Recruitment of chromatin remodelling factors during gene activation via the glucocorticoid receptor N-terminal domain.
Biochemical Society transactions 2000;28(4):410-4.
2000: Pike A C; Brzozowski A M; Walton J; Hubbard R E; Bonn T; Gustafsson J A; Carlquist M
Structural aspects of agonism and antagonism in the oestrogen receptor.
Biochemical Society transactions 2000;28(4):396-400.
1999: Windahl S H; Treuter E; Ford J; Zilliacus J; Gustafsson J A; McEwan I J
The nuclear-receptor interacting protein (RIP) 140 binds to the human glucocorticoid receptor and modulates hormone-dependent transactivation.
The Journal of steroid biochemistry and molecular biology 1999;71(3-4):93-102.
1999: Karas R H; Hodgin J B; Kwoun M; Krege J H; Aronovitz M; Mackey W; Gustafsson J A; Korach K S; Smithies O; Mendelsohn M E
Estrogen inhibits the vascular injury response in estrogen receptor beta-deficient female mice.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):15133-6.
1999: Vidal O; Lindberg M; Sävendahl L; Lubahn D B; Ritzen E M; Gustafsson J A; Ohlsson C
Disproportional body growth in female estrogen receptor-alpha-inactivated mice.
Biochemical and biophysical research communications 1999;265(2):569-71.
1999: Ogawa S; Chan J; Chester A E; Gustafsson J A; Korach K S; Pfaff D W
Survival of reproductive behaviors in estrogen receptor beta gene-deficient (betaERKO) male and female mice.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12887-92.
1999: Windahl S H; Vidal O; Andersson G; Gustafsson J A; Ohlsson C
Increased cortical bone mineral content but unchanged trabecular bone mineral density in female ERbeta(-/-) mice.
The Journal of clinical investigation 1999;104(7):895-901.
1999: Pike A C; Brzozowski A M; Hubbard R E; Bonn T; Thorsell A G; Engström O; Ljunggren J; Gustafsson J A; Carlquist M
Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist.
The EMBO journal 1999;18(17):4608-18.
1999: Wallberg A E; Neely K E; Gustafsson J A; Workman J L; Wright A P; Grant P A
Histone acetyltransferase complexes can mediate transcriptional activation by the major glucocorticoid receptor activation domain.
Molecular and cellular biology 1999;19(9):5952-9.
1999: Karlsson H; Gustafsson J A; Mode A
Cis desensitizes GH induced Stat5 signaling in rat liver cells.
Molecular and cellular endocrinology 1999;154(1-2):37-43.
1999: Enmark E; Gustafsson J A
Oestrogen receptors - an overview.
Journal of internal medicine 1999;246(2):133-8.
1999: Wiebel F F; Steffensen K R; Treuter E; Feltkamp D; Gustafsson J A
Ligand-independent coregulator recruitment by the triply activatable OR1/retinoid X receptor-alpha nuclear receptor heterodimer.
Molecular endocrinology (Baltimore, Md.) 1999;13(7):1105-18.
1999: Lind U; Greenidge P; Gustafsson J A; Wright A P; Carlstedt-Duke J
Valine 571 functions as a regional organizer in programming the glucocorticoid receptor for differential binding of glucocorticoids and mineralocorticoids.
The Journal of biological chemistry 1999;274(26):18515-23.
1999: Mäkelä S; Savolainen H; Aavik E; Myllärniemi M; Strauss L; Taskinen E; Gustafsson J A; Häyry P
Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors alpha and beta.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):7077-82.
1999: Gustafsson J A
Seeking ligands for lonely orphan receptors.
Science (New York, N.Y.) 1999;284(5418):1285-6.
1999: Miranda-Vizuete A; Damdimopoulos A E; Pedrajas J R; Gustafsson J A; Spyrou G
Human mitochondrial thioredoxin reductase cDNA cloning, expression and genomic organization.
European journal of biochemistry / FEBS 1999;261(2):405-12.
1999: Pircher T J; Petersen H; Gustafsson J A; Haldosén L A
Extracellular signal-regulated kinase (ERK) interacts with signal transducer and activator of transcription (STAT) 5a.
Molecular endocrinology (Baltimore, Md.) 1999;13(4):555-65.
1999: Feltkamp D; Wiebel F F; Alberti S; Gustafsson J A
Identification of a novel DNA binding site for nuclear orphan receptor OR1.
The Journal of biological chemistry 1999;274(15):10421-9.
1999: Lemmen J G; Broekhof J L; Kuiper G G; Gustafsson J A; van der Saag P T; van der Burg B
Expression of estrogen receptor alpha and beta during mouse embryogenesis.
Mechanisms of development 1999;81(1-2):163-7.
1999: Treuter E; Johansson L; Thomsen J S; Wärnmark A; Leers J; Pelto-Huikko M; Sjöberg M; Wright A P; Spyrou G; Gustafsson J A
Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors. Implications for the recruitment of TRAP and p160 coactivator complexes.
The Journal of biological chemistry 1999;274(10):6667-77.
1999: Pedrajas J R; Kosmidou E; Miranda-Vizuete A; Gustafsson J A; Wright A P; Spyrou G
Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae.
The Journal of biological chemistry 1999;274(10):6366-73.
1999: Johansson L; Thomsen J S; Damdimopoulos A E; Spyrou G; Gustafsson J A; Treuter E
The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERalpha and ERbeta.
The Journal of biological chemistry 1999;274(1):345-53.
1998: Nilsson S; Kuiper G; Gustafsson J A
ERbeta a Novel Estrogen Receptor Offers the Potential for New Drug Development.
Trends in endocrinology and metabolism: TEM 1998;9(10):387-95.
1998: Krege J H; Hodgin J B; Couse J F; Enmark E; Warner M; Mahler J F; Sar M; Korach K S; Gustafsson J A; Smithies O
Generation and reproductive phenotypes of mice lacking estrogen receptor beta.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15677-82.
1998: Kuiper G G; Shughrue P J; Merchenthaler I; Gustafsson J A
The estrogen receptor beta subtype: a novel mediator of estrogen action in neuroendocrine systems.
Frontiers in neuroendocrinology 1998;19(4):253-86.
1998: Kuiper G G; Lemmen J G; Carlsson B; Corton J C; Safe S H; van der Saag P T; van der Burg B; Gustafsson J A
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.
Endocrinology 1998;139(10):4252-63.
1998: Leers J; Treuter E; Gustafsson J A
Mechanistic principles in NR box-dependent interaction between nuclear hormone receptors and the coactivator TIF2.
Molecular and cellular biology 1998;18(10):6001-13.
1998: Gustafsson J A
Therapeutic potential of selective estrogen receptor modulators.
Current opinion in chemical biology 1998;2(4):508-11.
1998: Almlöf T; Wallberg A E; Gustafsson J A; Wright A P
Role of important hydrophobic amino acids in the interaction between the glucocorticoid receptor tau 1-core activation domain and target factors.
Biochemistry 1998;37(26):9586-94.
1998: Treuter E; Albrektsen T; Johansson L; Leers J; Gustafsson J A
A regulatory role for RIP140 in nuclear receptor activation.
Molecular endocrinology (Baltimore, Md.) 1998;12(6):864-81.
1998: Nord M; Låg M; Cassel T N; Randmark M; Becher R; Barnes H J; Schwarze P E; Gustafsson J A; Lund J
Regulation of CCSP (PCB-BP/uteroglobin) expression in primary cultures of lung cells: involvement of C/EBP.
DNA and cell biology 1998;17(5):481-92.
1998: Mode A; Ahlgren R; Lahuna O; Gustafsson J A
Gender differences in rat hepatic CYP2C gene expression--regulation by growth hormone.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1998;8 Suppl B():61-7.
1998: Enmark E; Gustafsson J A
[Newly discovered estrogen receptor. New therapeutic possibilities in postmenopausal symptoms, osteoporosis, cancer of the breast and prostate]
Läkartidningen 1998;95(17):1945-9.
1998: Fernández L; Flores-Morales A; Lahuna O; Sliva D; Norstedt G; Haldosén L A; Mode A; Gustafsson J A
Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C.
Endocrinology 1998;139(4):1815-24.
1998: Flores-Morales A; Pircher T J; Silvennoinen O; Gustafsson J A; Sanchez-Gomez M; Norstedt G; Haldosén L A; Wood T J
In vitro interaction between STAT 5 and JAK 2; dependence upon phosphorylation status of STAT 5 and JAK 2.
Molecular and cellular endocrinology 1998;138(1-2):1-10.
1998: Hedlund E; Gustafsson J A; Warner M
Cytochrome P450 in the brain: 2B or not 2B.
Trends in pharmacological sciences 1998;19(3):82-5.
1998: Hellmold H; Rylander T; Magnusson M; Reihnér E; Warner M; Gustafsson J A
Characterization of cytochrome P450 enzymes in human breast tissue from reduction mammaplasties.
The Journal of clinical endocrinology and metabolism 1998;83(3):886-95.
1998: Huang C J; Feltkamp D; Nilsson S; Gustafsson J A
Synergistic activation of RLD-1 by agents triggering PKA and PKC dependent signalling.
Biochemical and biophysical research communications 1998;243(3):657-63.
1998: Miranda-Vizuete A; Gustafsson J A; Spyrou G
Molecular cloning and expression of a cDNA encoding a human thioredoxin-like protein.
Biochemical and biophysical research communications 1998;243(1):284-8.
1998: Pereira T M; Carlstedt-Duke J; Lechner M C; Gustafsson J A
Identification of a functional glucocorticoid response element in the CYP3A1/IGC2 gene.
DNA and cell biology 1998;17(1):39-49.
1998: Sørensen H N; Treuter E; Gustafsson J A
Regulation of peroxisome proliferator-activated receptors.
Vitamins and hormones 1998;54():121-66.
1998: Warner M; Hellmold H; Magnusson M; Rylander T; Hedlund E; Gustafsson J A
Extrahepatic cytochrome P450: role in in situ toxicity and cell-specific hormone sensitivity.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1998;20():455-63.
1998: Gustafsson J A; Kuiper G; Enmark E; Treuter E; Rafter J
Receptor-mediated toxicity.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1998;20():21-8.
1997: Enmark E; Pelto-Huikko M; Grandien K; Lagercrantz S; Lagercrantz J; Fried G; Nordenskjöld M; Gustafsson J A
Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern.
The Journal of clinical endocrinology and metabolism 1997;82(12):4258-65.
1997: Pircher T J; Flores-Morales A; Mui A L; Saltiel A R; Norstedt G; Gustafsson J A; Haldosén L A
Mitogen-activated protein kinase kinase inhibition decreases growth hormone stimulated transcription mediated by STAT5.
Molecular and cellular endocrinology 1997;133(2):169-76.
1997: Brzozowski A M; Pike A C; Dauter Z; Hubbard R E; Bonn T; Engström O; Ohman L; Greene G L; Gustafsson J A; Carlquist M
Molecular basis of agonism and antagonism in the oestrogen receptor.
Nature 1997;389(6652):753-8.
1997: Pettersson K; Grandien K; Kuiper G G; Gustafsson J A
Mouse estrogen receptor beta forms estrogen response element-binding heterodimers with estrogen receptor alpha.
Molecular endocrinology (Baltimore, Md.) 1997;11(10):1486-96.
1997: Ford J; McEwan I J; Wright A P; Gustafsson J A
Involvement of the transcription factor IID protein complex in gene activation by the N-terminal transactivation domain of the glucocorticoid receptor in vitro.
Molecular endocrinology (Baltimore, Md.) 1997;11(10):1467-75.
1997: Meyer T; Gustafsson J A; Carlstedt-Duke J
Glucocorticoid-dependent transcriptional repression of the osteocalcin gene by competitive binding at the TATA box.
DNA and cell biology 1997;16(8):919-27.
1997: Witkowska H E; Carlquist M; Engström O; Carlsson B; Bonn T; Gustafsson J A; Shackleton C H
Characterization of bacterially expressed rat estrogen receptor beta ligand binding domain by mass spectrometry: structural comparison with estrogen receptor alpha.
Steroids 1997;62(8-9):621-31.
1997: Wiebel F F; Gustafsson J A
Heterodimeric interaction between retinoid X receptor alpha and orphan nuclear receptor OR1 reveals dimerization-induced activation as a novel mechanism of nuclear receptor activation.
Molecular and cellular biology 1997;17(7):3977-86.
1997: Kuiper G G; Gustafsson J A
The novel estrogen receptor-beta subtype: potential role in the cell- and promoter-specific actions of estrogens and anti-estrogens.
FEBS letters 1997;410(1):87-90.
1997: Henriksson A; Almlöf T; Ford J; McEwan I J; Gustafsson J A; Wright A P
Role of the Ada adaptor complex in gene activation by the glucocorticoid receptor.
Molecular and cellular biology 1997;17(6):3065-73.
1997: van der Burg B; Liden J; Okret S; Delaunay F; Wissink S; van der Saag P T; Gustafsson J A
Nuclear Factor-kappa B Repression in Antiinflammation and Immunosuppression by Glucocorticoids.
Trends in endocrinology and metabolism: TEM 1997;8(4):152-7.
1997: Warner M; Hellmold H; Yoshida S; Liao D; Hedlund E; Gustafsson J A
Cytochrome P450 in the breast and brain: role in tissue-specific activation of xenobiotics.
Mutation research 1997;376(1-2):79-85.
1997: Westin S; Sonneveld E; van der Leede B M; van der Saag P T; Gustafsson J A; Mode A
CYP2C7 expression in rat liver and hepatocytes: regulation by retinoids.
Molecular and cellular endocrinology 1997;129(2):169-79.
1997: Kuiper G G; Carlsson B; Grandien K; Enmark E; Häggblad J; Nilsson S; Gustafsson J A
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta.
Endocrinology 1997;138(3):863-70.
1997: McEwan I J; Wright A P; Gustafsson J A
Mechanism of gene expression by the glucocorticoid receptor: role of protein-protein interactions.
BioEssays : news and reviews in molecular, cellular and developmental biology 1997;19(2):153-60.
1997: Almlöf T; Gustafsson J A; Wright A P
Role of hydrophobic amino acid clusters in the transactivation activity of the human glucocorticoid receptor.
Molecular and cellular biology 1997;17(2):934-45.

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