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Steven Clark

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Steven S Clark
Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells.
Steven S Clark; Li Zhong; Daniele Filiault; Sarah Perman; Zhibin Ren; Michael Gould; Xinhai Yang
Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Raf-independent fashion.
Steven S Clark; Sarah Perman; M B Sahin; G J Jenkins; J A Elegbede
Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest.

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All Publications

2006: Steven S Clark
Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells.
Oncology 2006;70(1):13-8.
2003: Steven S Clark; Li Zhong; Daniele Filiault; Sarah Perman; Zhibin Ren; Michael Gould; Xinhai Yang
Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Raf-independent fashion.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(12):4494-504.
2002: Steven S Clark; Sarah Perman; M B Sahin; G J Jenkins; J A Elegbede
Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest.
Leukemia 2002;16(2):213-22.
2000: E Y Chen; B J Swanson; Steven S Clark
Transformation of undifferentiated Thy-1lo B220+ thymic lymphoid cells by the Abelson murine leukemia virus.
Developmental immunology 2000;8(1):1-18.
1999: M B Sahin; Sarah Perman; G Jenkins; Steven S Clark
Perillyl alcohol selectively induces G0/G1 arrest and apoptosis in Bcr/Abl-transformed myeloid cell lines.
Leukemia 1999;13(10):1581-91.
1997: Steven S Clark
Recurring proviral integration suggests a role for proto-oncogene activation in thymomas induced with Mo-MuLV-rescued BCR/ABL virus.
Leukemia 1997;11(7):1026-33.
1995: M Fizzotti; Steven S Clark
Bone marrow stroma-dependent modulation of CD45R isoform expression on Abelson virus transformed pre-B cells.
Immunological investigations 1995;24(3):509-22.
1995: Steven S Clark; Y Liang
Increased detection of specific tyrosine phosphoproteins correlates with tumor progression of Abelson virus-infected lymphocytes.
Leukemia 1995;9(1):165-74.
1994: Steven S Clark; Y Liang; C K Reedstrom; S Q Wu
Nonrandom cytogenetic changes accompany malignant progression in clonal lines abelson virus-infected lymphocytes.
Blood 1994;84(12):4301-9.
1994: M Fizzotti; E Y Chen; M P Link; A J Carroll; L Foroni; T H Rabbitts; W M Crist; Steven S Clark
Simultaneous expression of RBTN-2 and BCR-ABL oncogenes in a T-ALL with a t(11;14)(p13;q11) and a late-appearing Philadelphia chromosome.
Leukemia 1994;8(7):1124-30.
1994: K R Oettel; O H Wesly; Mark R Albertini; Jacquelyn A Hank; O Iliopolis; Jeffrey A Sosman; K Voelkerding; S Q Wu; Steven S Clark; Paul M Sondel
Allogeneic T-cell clones able to selectively destroy Philadelphia chromosome-bearing (Ph1+) human leukemia lines can also recognize Ph1- cells from the same patient.
Blood 1994;83(11):3390-402.
1993: Steven S Clark; E Chen; M Fizzotti; O N Witte; V Malkovska
BCR-ABL and v-abl oncogenes induce distinct patterns of thymic lymphoma involving different lymphocyte subsets.
Journal of virology 1993;67(10):6033-46.
1993: A A MacKinney; Steven S Clark; W Borcherding; M Fizzotti; R Hong
Simultaneous demonstration of the Philadelphia chromosome in T, B, and myeloid cells.
American journal of hematology 1993;44(1):48-52.
1991: Stephen D Nimer; David W Golde; K Kwan; K Lee; Steven S Clark; Richard Champlin
In vitro production of granulocyte-macrophage colony-stimulating factor in aplastic anemia: possible mechanisms of action of antithymocyte globulin.
Blood 1991;78(1):163-8.
1991: Mark R Albertini; J A Nicklas; B F Chastenay; T C Hunter; R J Albertini; Steven S Clark; Jacquelyn A Hank; Paul M Sondel
Analysis of T cell receptor beta and gamma genes from peripheral blood, regional lymph node and tumor-infiltrating lymphocyte clones from melanoma patients.
Cancer immunology, immunotherapy : CII 1991;32(5):325-30.
1990: Charles L Sawyers; L Timson; E S Kawasaki; Steven S Clark; Owen N Witte; Richard Champlin
Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(2):563-7.
1989: Vesna Najfeld; J Cuttner; A Figur; E S Kawasaki; Owen N Witte; Steven S Clark
P185BCR-ABL in two patients with late appearing Philadelphia chromosome-positive acute nonlymphocytic leukemia.
Leukemia 1989;3(12):841-6.
1989: L W Dow; N Tachibana; Susana C Raimondi; S J Lauer; Owen N Witte; Steven S Clark
Comparative biochemical and cytogenetic studies of childhood acute lymphoblastic leukemia with the Philadelphia chromosome and other 22q 11 variants.
Blood 1989;73(5):1291-7.
1989: Steven S Clark; W M Crist; Owen N Witte
Molecular pathogenesis of Ph-positive leukemias.
Annual review of medicine 1989;40():113-22.
1988: E S Kawasaki; Steven S Clark; M Y Coyne; S D Smith; Richard Champlin; Owen N Witte; F P McCormick
Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(15):5698-702.
1988: Steven S Clark; Jami McLaughlin; M Timmons; Ann Marie Pendergast; Y Ben-Neriah; L W Dow; W Crist; G Rovera; S D Smith; Owen N Witte
Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL).
Science (New York, N.Y.) 1988;239(4841 Pt 1):775-7.
1987: Steven S Clark; J McLaughlin; W M Crist; R Champlin; O N Witte
Unique forms of the abl tyrosine kinase distinguish Ph1-positive CML from Ph1-positive ALL.
Science (New York, N.Y.) 1987;235(4784):85-8.
1986: J B Konopka; Steven S Clark; J McLaughlin; M Nitta; Y Kato; A Strife; Bayard Clarkson; O N Witte
Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(11):4049-52.
1986: L Schiff-Maker; M C Burns; J B Konopka; Steven S Clark; O N Witte; N Rosenberg
Monoclonal antibodies specific for v-abl- and c-abl-encoded molecules.
Journal of virology 1986;57(3):1182-6.
1985: I Stroynowski; Steven S Clark; L A Henderson; Leroy Hood; Minnie McMillan; J Forman
Interaction of alpha 1 with alpha 2 region in class I MHC proteins contributes determinants recognized by antibodies and cytotoxic T cells.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(3):2160-6.
1985: Steven S Clark; S Geier; Stanley G Nathenson; J Forman
Analysis of associative recognition determinants on class I H-2Kb mutant molecules.
Immunogenetics 1985;22(4):391-7.
1984: Steven S Clark; J Forman
Functional aspects of class I MHC molecule domains.
Survey of immunologic research 1984;3(2-3):179-83.
1983: Steven S Clark; J Forman
Allogeneic and associative recognition determinants of H-2 molecules.
Transplantation proceedings 1983;15(4):2090-2.
1983: M C Zuniga; B Malissen; Minnie McMillan; P R Brayton; Steven S Clark; J Forman; Leroy Hood
Expression and function of transplantation antigens with altered or deleted cytoplasmic domains.
Cell 1983;34(2):535-44.
1983: Steven S Clark; J Forman
Structure function relationship of class I MHC molecules.
Survey of immunologic research 1983;2(3):203-6.