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Anastassis Perraks

Research Profile

Procedures

X Ray Crystallography

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Wilco Nijenhuis; Anastassis Perraks; Berend Snel; Eelco Tromer; Maria H J van Osch; Mathijs Vleugel; Eleonore von Castelmur; Valeria De Marco; Dene Littler; Geert J P L Kops
A TPR domain-containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B.
Anna J S Houben; Alexander Fish; Jens Hausmann; Anastassis Perraks; Els M A van de Westerlo; Toin H van Kuppevelt; Laurens van Meeteren; Xander M R van Wijk; Leonie van Zeijl; Wouter H Moolenaar
The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans.
Jens Hausmann; Anastassis Perraks; Wouter H Moolenaar
Structure-function relationships of autotaxin, a secreted lysophospholipase D.

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All Publications

2013: Wilco Nijenhuis; Anastassis Perraks; Berend Snel; Eelco Tromer; Maria H J van Osch; Mathijs Vleugel; Eleonore von Castelmur; Valeria De Marco; Dene Littler; Geert J P L Kops
A TPR domain-containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B.
The Journal of cell biology 2013;201(2):217-31.
2013: Anna J S Houben; Alexander Fish; Jens Hausmann; Anastassis Perraks; Els M A van de Westerlo; Toin H van Kuppevelt; Laurens van Meeteren; Xander M R van Wijk; Leonie van Zeijl; Wouter H Moolenaar
The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans.
The Journal of biological chemistry 2013;288(1):510-9.
2013: Jens Hausmann; Anastassis Perraks; Wouter H Moolenaar
Structure-function relationships of autotaxin, a secreted lysophospholipase D.
Advances in biological regulation 2013;53(1):112-7.
2012: Silvia Jansen; Robbie P Joosten; Frank P Luyten; Wouter H Moolenaar; Anastassis Perraks; Chris Ulens; Maarten Van Acker; Claudia Winkler; Maria Andries; Mathieu Bollen
Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification.
Structure (London, England : 1993) 2012;20(11):1948-59.
2012: Henri G A M van Luenen; Bas van Steensel; Arno Velds; Carol Farris; Paul-Andre Genest; Andrew Haydock; Tatjana Heidebrecht; Sabrina Jan; Ron Kerkhoven; Peter J Myler; Marja Nieuwland; Ludo Pagie; Anastassis Perraks; Gowthaman Ramasamy; Pankaj Tripathi; Saara Vainio; Piet Borst
Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania.
Cell 2012;150(5):909-21.
2012: Tatjana Heidebrecht; Kenneth A Johnson; Piet Borst; Alexander Fish; Eleonore von Castelmur; Giuseppe Zaccai; Anastassis Perraks
Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.
Journal of the American Chemical Society 2012;134(32):13357-65.
2012: Saskia J E Suijkerbuijk; Teunis J P van Dam; Mathijs Vleugel; Eleonore von Castelmur; Afonso M S Duarte; Nina C Hubner; Gulsun Elif Karagoz; Anastassis Perraks; Stefan G D Rüdiger; Berend Snel; Geert J P L Kops
The vertebrate mitotic checkpoint protein BUBR1 is an unusual pseudokinase.
Developmental cell 2012;22(6):1321-9.
2012: Robbie P Joosten; Garib N Murshudov; Krista Joosten; Anastassis Perraks
PDB_REDO: constructive validation, more than just looking for errors.
Acta crystallographica. Section D, Biological crystallography 2012;68(Pt 4):484-96.
2012: Christophe Caillat; Anastassis Perraks
Cdt1 and geminin in DNA replication initiation.
Sub-cellular biochemistry 2012;62():71-87.
2011: Randy J Read; Jane S Richardson; William H Sheffler; Janet L Smith; Ian J Tickle; Gert Vriend; Paul D Adams; W Bryan Arendall; Axel T Brunger; Paul Emsley; Robbie P Joosten; Gerard J Kleywegt; Evgeny Krissinel; Thomas Lütteke; Zbyszek Otwinowski; Anastassis Perraks; Peter H Zwart
A new generation of crystallographic validation tools for the protein data bank.
Structure (London, England : 1993) 2011;19(10):1395-412.
2011: Alex C Faesen; Huib Ovaa; Anastassis Perraks; Anitha Shanmugham; Annette M G Dirac; Titia K Sixma
Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase.
Molecular cell 2011;44(1):147-59.
2011: Wouter H Moolenaar; Anastassis Perraks
Insights into autotaxin: how to produce and present a lipid mediator.
Nature reviews. Molecular cell biology 2011;12(10):674-9.
2011: Maria Chiara Monti; Anastassis Perraks; Titia K Sixma; Robert H H van den Heuvel; Herrie H K Winterwerp; Arjan Barendregt; Serge X Cohen; Alexander Fish; Peter Friedhoff; Albert J R Heck; Joyce H G Lebbink
Native mass spectrometry provides direct evidence for DNA mismatch-induced regulation of asymmetric nucleotide binding in mismatch repair protein MutS.
Nucleic acids research 2011;39(18):8052-64.
2011: Anastassis Perraks; Stephen Cusack; Andrea Musacchio; Carlo Petosa
Investigating a macromolecular complex: the toolkit of methods.
Journal of structural biology 2011;175(2):106-12.
2011: Anastassis Perraks; David I Stuart; Susan Daenke; Joel L Sussman
From SPINE to SPINE-2 complexes and beyond.
Journal of structural biology 2011;175(2):105.
2011: Mark P A Luna-Vargas; Valeria De Marco; Andrea Alfieri; Patrick H N Celie; Evangelos Christodoulou; Marcello Clerici; Richard G Hibbert; Dene Littler; Danny D Sahtoe; Titia K Sixma; Magda Stadnik; Willem J van Dijk; Anastassis Perraks
Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases.
Journal of structural biology 2011;175(2):113-9.
2011: Didier Busso; Konrad Büssow; Jared L Cartwright; Rachel Adamson; Nick S Berrow; Louise Bird; Elena Blagova; Ada Dantes; Gert E Folkers; Arie Geerlof; Tatjana Heidebrecht; Udo Heinemann; Yossi Jacobovitch; Raymond J Owens; Yoav Peleg; Anastassis Perraks; Andrea Polewacz; Claudia Quedenau; Christophe Romier; Loubna Salim; Anja Schuetz; Joel L Sussman; Edouard Troesch; Julia Walton; Matthias Wilmanns; Keith S Wilson; Patrick H N Celie
Expression of protein complexes using multiple Escherichia coli protein co-expression systems: a benchmarking study.
Journal of structural biology 2011;175(2):159-70.
2011: Harald M H G Albers; Jens Hausmann; Loes J D Hendrickx; Anastassis Perraks; Rob J P van Tol; Huib Ovaa
Structure-based design of novel boronic acid-based inhibitors of autotaxin.
Journal of medicinal chemistry 2011;54(13):4619-26.
2011: Dafni-Eleutheria Pefani; Anastassis Perraks; Magda Spella; Ioanna-Eleni Symeonidou; Stavros Taraviras; Maria Dimaki; Nickolas Karantzelis; Christina Kyrousi; Eirini Mitsiki; Zoi Lygerou
Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression.
The Journal of biological chemistry 2011;286(26):23234-46.
2011: Tatjana Heidebrecht; Sabrina Jan; Robbie P Joosten; Dene Littler; Piet Borst; Michael J Chalmers; Evangelos Christodoulou; Patrick R Griffin; Rajesh K Grover; Bas ter Riet; Henri G A M van Luenen; Paul Wentworth; Anastassis Perraks
The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1.
Nucleic acids research 2011;39(13):5715-28.
2011: Jens Hausmann; Satwik Kamtekar; Evangelos Christodoulou; Jacqueline E Day; Tao Wu; Zachary Fulkerson; Harald M H G Albers; Laurens van Meeteren; Anna J S Houben; Leonie van Zeijl; Silvia Jansen; Maria Andries; Troii Hall; Lyle E Pegg; Timothy E Benson; Mobien Kasiem; Karl Harlos; Craig W Vander Kooi; Susan S Smyth; Huib Ovaa; Mathieu Bollen; Andrew James Morris; Wouter H Moolenaar; Anastassis Perraks
Structural basis of substrate discrimination and integrin binding by autotaxin.
Nature structural & molecular biology 2011;18(2):198-204.
2011: Andriy Kryshtafovych; Andreas Lingel; Karolina Michalska; Gaetano T Montelione; John Moult; José M Otero; Anastassis Perraks; Juan C Pizarro; Theresa A Ramelot; Francois Rousseau; Sergio G Bartual; J Fernando Bazan; Helen Berman; Darren E Casteel; Evangelos Christodoulou; John K Everett; Jens Hausmann; Tatjana Heidebrecht; Tanya Hills; Raymond Hui; John F Hunt; Andrzej Joachimiak; Michael A Kennedy; Choel Kim; Jayaraman Seetharaman; Liang Tong; Mark J van Raaij; Amy K Wernimont; Jasmine Young; Torsten Schwede
Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction.
Proteins 2011;79 Suppl 10():6-20.
2010: Mark A Brooks; Kamil Gewartowski; Eirini Mitsiki; Juliette Létoquart; Roland A Pache; Ysaline Billier; Michela Bertero; Margot Corréa; Mariusz Czarnocki-Cieciura; Michal Dadlez; Véronique Henriot; Noureddine Lazar; Lila Delbos; Dorothée Lebert; Jan Piwowarski; Pascal Rochaix; Bettina Böttcher; Luis Serrano; Bertrand Séraphin; Herman van Tilbeurgh; Patrick Aloy; Anastassis Perraks; Andrzej Dziembowski
Systematic bioinformatics and experimental validation of yeast complexes reduces the rate of attrition during structural investigations.
Structure (London, England : 1993) 2010;18(9):1075-82.
2010: Jens Hausmann; Evangelos Christodoulou; Mobien Kasiem; Valeria De Marco; Laurens van Meeteren; Wouter H Moolenaar; Danny Axford; Robin L Owen; Gwyndaf Evans; Anastassis Perraks
Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein.
Acta crystallographica. Section F, Structural biology and crystallization communications 2010;66(Pt 9):1130-5.
2010: D R Littler; Monica Alvarez-Fernandez; A Stein; R G Hibbert; T Heidebrecht; P Aloy; R H Medema; Anastassis Perraks
Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence.
Nucleic acids research 2010;38(13):4527-38.
2010: D R Littler; L J Brown; S N Breit; Anastassis Perraks; P M G Curmi
Structure of human CLIC3 at 2 A resolution.
Proteins 2010;78(6):1594-600.
2009: V De Marco; P J Gillespie; A Li; N Karantzelis; Evangelos Christodoulou; Rob Klompmaker; S van Gerwen; A Fish; M V Petoukhov; Maria Stefanou Iliou; Z Lygerou; René H Medema; J J Blow; D I Svergun; S Taraviras; Anastassis Perraks
Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(47):19807-12.
2009: Boris Rodenko; Mireille Toebes; Patrick H N Celie; Anastassis Perraks; Schumacher Ton; Huib Ovaa
Class I major histocompatibility complexes loaded by a periodate trigger.
Journal of the American Chemical Society 2009;131(34):12305-13.
2009: Patrick H N Celie; Mireille Toebes; Boris Rodenko; Huib Ovaa; Anastassis Perraks; Schumacher Ton
UV-induced ligand exchange in MHC class I protein crystals.
Journal of the American Chemical Society 2009;131(34):12298-304.
2009: Mark Hilge; Jan Aelen; Alice Foarce; Anastassis Perraks; Geerten W Vuister
Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14333-8.
2009: Wijnand T M Mooij; Eirini Mitsiki; Anastassis Perraks
ProteinCCD: enabling the design of protein truncation constructs for expression and crystallization experiments.
Nucleic acids research 2009;37(Web Server issue):W402-5.
2009: Chris Ulens; Atilla Akdemir; Aldo Jongejan; Rene van Elk; Sonia Bertrand; Anastassis Perraks; Rob Leurs; August B Smit; Titia K Sixma; Daniel Bertrand; Iwan J P De Esch
Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis.
Journal of medicinal chemistry 2009;52(8):2372-83.
2009: Kostas Repanas; Gloria Fuentes; Serge X Cohen; Alexandre Bonvin; Anastassis Perraks
Insights into the DNA cleavage mechanism of human LINE-1 retrotransposon endonuclease.
Proteins 2009;74(4):917-28.
2009: Wijnand T M Mooij; Serge X Cohen; Krista Joosten; Garib N Murshudov; Anastassis Perraks
"Conditional Restraints": Restraining the Free Atoms in ARP/wARP.
Structure (London, England : 1993) 2009;17(2):183-9.
2008: Barbara C M van de Weerdt; Dene R Littler; Rob Klompmaker; Angelina Huseinovic; Alex Fish; Anastassis Perraks; René H Medema
Polo-box domains confer target specificity to the Polo-like kinase family.
Biochimica et biophysica acta 2008;1783(6):1015-22.
2008: Krista Joosten; Serge X Cohen; Paul Emsley; Wijnand Mooij; Victor S Lamzin; Anastassis Perraks
A knowledge-driven approach for crystallographic protein model completion.
Acta crystallographica. Section D, Biological crystallography 2008;64(Pt 4):416-24.
2008: Gerrit G Langer; Serge X Cohen; Victor S Lamzin; Anastassis Perraks
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7.
Nature protocols 2008;3(7):1171-9.
2008: Anastassis Perraks; Christophe Romier
Assembly of protein complexes by coexpression in prokaryotic and eukaryotic hosts: an overview.
Methods in molecular biology (Clifton, N.J.) 2008;426():247-56.
2008: Serge X Cohen; Marouane Ben Jelloul; Fei Long; Alexei A Vagin; Puck Knipscheer; Joyce H G Lebbink; Titia K Sixma; Victor S Lamzin; Garib N Murshudov; Anastassis Perraks
ARP/wARP and molecular replacement: the next generation.
Acta crystallographica. Section D, Biological crystallography 2008;64(Pt 1):49-60.
2007: Martijn Kedde; Markus J Strasser; Bijan Boldajipour; Joachim A F Oude Vrielink; Krasimir Slanchev; Carlos le Sage; Remco Nagel; P Mathijs Voorhoeve; Josyanne van Duijse; Ulf Ørom; Anders H Lund; Anastassis Perraks; erez raz; Reuven Agami
RNA-binding protein Dnd1 inhibits microRNA access to target mRNA.
Cell 2007;131(7):1273-86.
2007: Mark Hilge; Jan Aelen; Anastassis Perraks; Geerten W Vuister
Structural basis for Ca2+ regulation in the Na+/Ca2+ exchanger.
Annals of the New York Academy of Sciences 2007;1099():7-15.
2007: Kostas Repanas; Nora Zingler; Liliana E Layer; Gerald G Schumann; Anastassis Perraks; Oliver Weichenrieder
Determinants for DNA target structure selectivity of the human LINE-1 retrotransposon endonuclease.
Nucleic acids research 2007;35(14):4914-26.
2007: Zhong Yu; Paul-André Genest; Bas ter Riet; Kate Sweeney; Courtney DiPaolo; Rudo Kieft; Evangelos Christodoulou; Anastassis Perraks; Jana M Simmons; Robert P Hausinger; Henri G A M van Luenen; Daniel J Rigden; Robert Sabatini; Piet Borst
The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.
Nucleic acids research 2007;35(7):2107-15.
2007: Guillaume X Evrard; Gerrit G Langer; Anastassis Perraks; Victor S Lamzin
Assessment of automatic ligand building in ARP/wARP.
Acta crystallographica. Section D, Biological crystallography 2007;63(Pt 1):108-17.
2006: Ivan Mamely; Marcel A T M van Vugt; Veronique A J Smits; Jennifer I Semple; Bennie Lemmens; Anastassis Perraks; René H Medema; Raimundo Freire
Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery.
Current biology : CB 2006;16(19):1950-5.
2006: Christophe Romier; Marouane Ben Jelloul; Shira Albeck; Gretel Buchwald; Didier Busso; Patrick H N Celie; Evangelos Christodoulou; Valeria De Marco; Suzan van Gerwen; Puck Knipscheer; Joyce H G Lebbink; Valerie Notenboom; Arnaud Poterszman; Natacha Rochel; Serge X Cohen; Tamar Unger; Joel Sussman; Dino Moras; Titia K Sixma; Anastassis Perraks
Co-expression of protein complexes in prokaryotic and eukaryotic hosts: experimental procedures, database tracking and case studies.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1232-42.
2006: L Banci; I Bertini; S Cusack; R N de Jong; U Heinemann; E Yvonne Jones; F Kozielski; K Maskos; Albrecht Messerschmidt; R Owens; Anastassis Perraks; Arnaud Poterszman; G Schneider; Christian Siebold; I Silman; Titia K Sixma; Guillaume Stewart-Jones; Joel Sussman; Jean-Claude Thierry; Dino Moras
First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1208-17.
2006: S Albeck; Pedro Alzari; C Andreini; L Banci; I M Berry; I Bertini; C Cambillau; B Canard; L Carter; S X Cohen; J M Diprose; O Dym; R M Esnouf; C Felder; François Ferron; F Guillemot; R Hamer; M Ben Jelloul; R A Laskowski; T Laurent; S Longhi; R Lopez; Claudio Luchinat; H Malet; T Mochel; R J Morris; L Moulinier; T Oinn; Anne Pajon; Y Peleg; Anastassis Perraks; O Poch; J Prilusky; A Rachedi; R Ripp; A Rosato; I Silman; D I Stuart; Joel Sussman; J C Thierry; julie thompson; J M Thornton; T Unger; B Vaughan; Wim Vranken; J D Watson; G Whamond; K Henrick
SPINE bioinformatics and data-management aspects of high-throughput structural biology.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1184-95.
2006: Mohammad W Bahar; C Ballard; Serge X Cohen; Kevin Cowtan; Eleanor J Dodson; Paul Emsley; Robert M Esnouf; R Keegan; Victor S Lamzin; Gerrit G Langer; Vladimir M Levdikov; Fei Long; C Meier; Axel Muller; Garib N Murshudov; Anastassis Perraks; Christian Siebold; N Stein; M G W Turkenburg; Alexei A Vagin; Martyn D Winn; G Winter; Keith S Wilson
SPINE workshop on automated X-ray analysis: a progress report.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1170-83.
2006: Ian M Berry; Orly Dym; Robert M Esnouf; Karl Harlos; Ran Meged; Anastassis Perraks; Joel Sussman; thomas walter; J Wilson; Albrecht Messerschmidt
SPINE high-throughput crystallization, crystal imaging and recognition techniques: current state, performance analysis, new technologies and future aspects.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1137-49.
2006: A Radu Aricescu; Rene Assenberg; Roslyn M Bill; Didier Busso; Veronica T Chang; Simon J Davis; A Dubrovsky; L Gustafsson; Kristina Hedfalk; U Heinemann; I M Jones; D Ksiazek; C Lang; K Maskos; Albrecht Messerschmidt; Sofia Macieira; Yoav Peleg; Anastassis Perraks; Arnaud Poterszman; G Schneider; Titia K Sixma; Joel Sussman; G Sutton; N Tarboureich; Tzviya Zeev-Ben-Mordehai; E Yvonne Jones
Eukaryotic expression: developments for structural proteomics.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1114-24.
2006: Pedro Alzari; Helena Berglund; Nick S Berrow; Elena V Blagova; Didier Busso; C Cambillau; Valérie Campanacci; Evangelos Christodoulou; S Eiler; Mark J Fogg; G Folkers; Arie Geerlof; D Hart; Ahmed Haouz; Maria Dolores Herman; Sofia Macieira; Pär Nordlund; Anastassis Perraks; Sophie Quevillon-Cheruel; F Tarandeau; Herman van Tilbeurgh; Tamar Unger; M P A Luna-Vargas; Milko Velarde; M Willmanns; Raymond J Owens
Implementation of semi-automated cloning and prokaryotic expression screening: the impact of SPINE.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1103-13.
2006: Gretel Buchwald; Petra van der Stoop; Oliver Weichenrieder; Anastassis Perraks; Maarten van Lohuizen; Titia K Sixma
Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b.
The EMBO journal 2006;25(11):2465-74.
2006: Anna-Pavlina G Haramis; Anastassis Perraks
Selectivity and promiscuity in Eph receptors.
Structure (London, England : 1993) 2006;14(2):169-71.
2005: Janet Newman; David Egan; thomas walter; Ran Meged; Ian M Berry; Marouane Ben Jelloul; Joel Sussman; David I Stuart; Anastassis Perraks
Towards rationalization of crystallization screening for small- to medium-sized academic laboratories: the PACT/JCSG+ strategy.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 10):1426-31.
2005: Sandy H M Litjens; Kevin Wilhelmsen; Jose M de Pereda; Anastassis Perraks; Arnoud Sonnenberg
Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin.
The Journal of biological chemistry 2005;280(23):22270-7.
2005: Laurens van Meeteren; Paula Ruurs; Evangelos Christodoulou; James W Goding; Hideo Takakusa; Kazuya Kikuchi; Anastassis Perraks; Tetsuo Nagano; Wouter H Moolenaar
Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.
The Journal of biological chemistry 2005;280(22):21155-61.
2004: Liz Potterton; Stuart McNicholas; Evgeny Krissinel; Jan Gruber; Kevin Cowtan; Paul Emsley; Garib N Murshudov; Serge Cohen; Anastassis Perraks; Martin Noble
Developments in the CCP4 molecular-graphics project.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 12 Pt 1):2288-94.
2004: Serge X Cohen; Richard J Morris; Francisco Fernandez; Marouane Ben Jelloul; Mattheos Kakaris; Venkataraman Parthasarathy; Victor S Lamzin; Gerard J Kleywegt; Anastassis Perraks
Towards complete validated models in the next generation of ARP/wARP.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 12 Pt 1):2222-9.
2004: Oliver Weichenrieder; Kostas Repanas; Anastassis Perraks
Crystal structure of the targeting endonuclease of the human LINE-1 retrotransposon.
Structure (London, England : 1993) 2004;12(6):975-86.
2004: Richard J Morris; Petrus H Zwart; Serge Cohen; Francisco Fernandez; Mattheos Kakaris; Olga Kirillova; Clemens Vonrhein; Anastassis Perraks; Victor S Lamzin
Breaking good resolutions with ARP/wARP.
Journal of synchrotron radiation 2004;11(Pt 1):56-9.
2003: Ganesh Natrajan; Meindert H Lamers; Jacqueline H Enzlin; Herrie H K Winterwerp; Anastassis Perraks; Titia K Sixma
Structures of Escherichia coli DNA mismatch repair enzyme MutS in complex with different mismatches: a common recognition mode for diverse substrates.
Nucleic acids research 2003;31(16):4814-21.
2003: Bing Xiao; James Spencer; Adrienne Clements; Nadeem Ali-Khan; Sibylle Mittnacht; Cristina Broceño; Manfred Burghammer; Anastassis Perraks; Ronen Marmorstein; Steven J Gamblin
Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2363-8.
2003: Richard J Morris; Anastassis Perraks; Victor S Lamzin
ARP/wARP and automatic interpretation of protein electron density maps.
Methods in enzymology 2003;374():229-44.
2002: Claudia Ruivenkamp; Tom van Wezel; Carlo Zanon; Alphons P M Stassen; Cestmir Vlcek; Tamás Csikós; Anita M Klous; Nikos Tripodis; Anastassis Perraks; Lucie Boerrigter; Peter C Groot; Jan Lindeman; Wolter J Mooi; Gerrit A Meijjer; Gert Scholten; Hans Dauwerse; Vaclav Paces; nico van zandwijk; Gert-Jan B van Ommen; Peter Demant
Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers.
Nature genetics 2002;31(3):295-300.
2002: Richard J Morris; Anastassis Perraks; Victor S Lamzin
ARP/wARP's model-building algorithms. I. The main chain.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 6 Pt 2):968-75.
2001: Anastassis Perraks; M Harkiolaki; K S Wilson; Victor S Lamzin
ARP/wARP and molecular replacement.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 10):1445-50.
2001: Mark Hilge; Anastassis Perraks; Jan Pieter Abrahams; Kaspar Winterhalter; Klaus Piontek; Sergio M Gloor
Structure elucidation of beta-mannanase: from the electron-density map to the DNA sequence.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 1):37-43.
2000: Victor S Lamzin; Anastassis Perraks
Current state of automated crystallographic data analysis.
Nature structural biology 2000;7 Suppl():978-81.
2000: Victor S Lamzin; Anastassis Perraks; G Bricogne; J Jiang; S Swaminathan; Joel Sussman
Apotheosis, not apocalypse: methods in protein crystallography.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 11):1510-1.
2000: Meindert H Lamers; Anastassis Perraks; J H Enzlin; Herrie H K Winterwerp; Niels De Wind; Titia K Sixma
The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch.
Nature 2000;407(6805):711-7.
2000: Andreas Bracher; Anastassis Perraks; T Dresbach; Heinrich Betz; Winfried Weissenhorn
The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis.
Structure (London, England : 1993) 2000;8(7):685-94.
2000: M A Walsh; Z Otwinowski; Anastassis Perraks; P M Anderson; A Joachimiak
Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required for formation of the enzyme active site.
Structure (London, England : 1993) 2000;8(5):505-14.
1999: Anastassis Perraks; Florent Cipriani; J C Castagna; L Claustre; Manfred Burghammer; Christian Riekel; S Cusack
Protein microcrystals and the design of a microdiffractometer: current experience and plans at EMBL and ESRF/ID13.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 10):1765-70.
1999: Anastassis Perraks; R Morris; Victor S Lamzin
Automated protein model building combined with iterative structure refinement.
Nature structural biology 1999;6(5):458-63.
1999: Anastassis Perraks; Ekaterini Antoniadou-Vyza; P Tsitsa; Victor S Lamzin; K S Wilson; S J Hamodrakas
Molecular, crystal and solution structure of a beta-cyclodextrin complex with the bromide salt of 2-(3-dimethylaminopropyl)tricyclo[3.3.1.1(3,7)]decan-2-ol, a potent antimicrobial drug.
Carbohydrate research 1999;317(1-4):19-28.
1998: Karin Valegård; Anke C Terwisscha van Scheltinga; Matthew D Lloyd; T Hara; S Ramaswamy; Anastassis Perraks; A Thompson; H J Lee; Jack E Baldwin; Christopher J Schofield; Janos Hajdu; Inger Andersson
Structure of a cephalosporin synthase.
Nature 1998;394(6695):805-9.
1998: S Cusack; H Belrhali; A Bram; Manfred Burghammer; Anastassis Perraks; Christian Riekel
Small is beautiful: protein micro-crystallography.
Nature structural biology 1998;5 Suppl():634-7.
1998: EJ Van Asselt; Anastassis Perraks; Kor H Kalk; Victor S Lamzin; Bauke W Dijkstra
Accelerated X-ray structure elucidation of a 36 kDa muramidase/transglycosylase using wARP.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 1):58-73.
1997: Gertie van Pouderoyen; René F Ketting; Anastassis Perraks; Ronald H Plasterk; Titia K Sixma
Crystal structure of the specific DNA-binding domain of Tc3 transposase of C.elegans in complex with transposon DNA.
The EMBO journal 1997;16(19):6044-54.
1997: H Tong; G Hateboer; Anastassis Perraks; René Bernards; Titia K Sixma
Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system.
The Journal of biological chemistry 1997;272(34):21381-7.
1997: Anastassis Perraks; Titia K Sixma; K S Wilson; Victor S Lamzin
wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models.
Acta crystallographica. Section D, Biological crystallography 1997;53(Pt 4):448-55.
1997: Anastassis Perraks; Christos Ouzounis; K S Wilson
Evolution of immunoglobulin-like modules in chitinases: their structural flexibility and functional implications.
Folding & design 1997;2(5):291-4.
1996: Constantinos E Vorgias; Anastassis Perraks; I Tews
Structure-function studies on the chitinolytic enzymes of Serratia marcescens chitinase and chitobiase.
Annals of the New York Academy of Sciences 1996;799():190-2.
1996: Ernst Schönbrunn; S Sack; S Eschenburg; Anastassis Perraks; F Krekel; Nikolaus Amrhein; Eckhard Mandelkow
Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin.
Structure (London, England : 1993) 1996;4(9):1065-75.
1996: Alexey Teplyakov; P Sebastiao; Galina Obmolova; Anastassis Perraks; George S Brush; Maurice J Bessman; Keith S Wilson
Crystal structure of bacteriophage T4 deoxynucleotide kinase with its substrates dGMP and ATP.
The EMBO journal 1996;15(14):3487-97.
1996: I Tews; Anastassis Perraks; A Oppenheim; Zbigniew Dauter; Keith S Wilson; Constantinos E Vorgias
Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease.
Nature structural biology 1996;3(7):638-48.
1996: PN Kanellopoulos; K Pavlou; Anastassis Perraks; B Agianian; Constantinos E Vorgias; C Mavrommatis; M Soufi; Paul Tucker; Stavros J Hamodrakas
The crystal structure of the complexes of concanavalin A with 4'-nitrophenyl-alpha-D-mannopyranoside and 4'-nitrophenyl-alpha-D-glucopyranoside.
Journal of structural biology 1996;116(3):345-55.
1995: Anastassis Perraks; Constantinos Constantinides; A Athanasiades; Stavros J Hamodrakas
PBM: a software package to create, display and manipulate interactively models of small molecules and proteins on IBM-compatible PCs.
Computer applications in the biosciences : CABIOS 1995;11(2):141-5.
1994: Anastassis Perraks; I Tews; Zbigniew Dauter; Ariella Oppenheim; Ilan Chet; Keith S Wilson; Constantinos E Vorgias
Crystal structure of a bacterial chitinase at 2.3 A resolution.
Structure (London, England : 1993) 1994;2(12):1169-80.
1994: Wojciech R Rypniewski; Anastassis Perraks; Constantinos E Vorgias; Keith S Wilson
Evolutionary divergence and conservation of trypsin.
Protein engineering 1994;7(1):57-64.