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Klaus Lindpaintner

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Laurie M Clotilde; Carol R Lauzon; Andrew Lin; Klaus Lindpaintner; Mark Muldoon; Alexandra Salvador; Yichun Xu; Clay Bernard; J Mark Carter
A 7-plex microbead-based immunoassay for serotyping Shiga toxin-producing Escherichia coli.
Narasimha V Hegde; Bhushan M Jayarao; Vivek Kapur; Klaus Lindpaintner; Mark Muldoon; Rebecca Cote; Chitrita DebRoy
Detection of the top six non-O157 Shiga toxin-producing Escherichia coli O groups by ELISA.
Jennifer R Harris; Robert Hewitt; Jane Kaye; Bartha Maria Knoppers; Klaus Lindpaintner; Jan-Eric Litton; Andres Metspalu; Bill Ollier; Lyle J Palmer; Aarno Palotie; Markus Pasterk; Markus Perola; Peter H J Riegman; Gert-Jan van Ommen; Martin Yuille; Marianna Bledsoe; Anthony J Brookes; Isabelle Budin-Ljøsne; Paul Burton; Rex Chisholm; David Cox; Mylène Deschênes; Isabel Fortier; Pierre Hainaut; Kurt Zatloukal
Toward a roadmap in global biobanking for health.

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2013: Laurie M Clotilde; Carol R Lauzon; Andrew Lin; Klaus Lindpaintner; Mark Muldoon; Alexandra Salvador; Yichun Xu; Clay Bernard; J Mark Carter
A 7-plex microbead-based immunoassay for serotyping Shiga toxin-producing Escherichia coli.
Journal of microbiological methods 2013;92(2):226-30.
2012: Narasimha V Hegde; Bhushan M Jayarao; Vivek Kapur; Klaus Lindpaintner; Mark Muldoon; Rebecca Cote; Chitrita DebRoy
Detection of the top six non-O157 Shiga toxin-producing Escherichia coli O groups by ELISA.
Foodborne pathogens and disease 2012;9(11):1044-8.
2012: Jennifer R Harris; Robert Hewitt; Jane Kaye; Bartha Maria Knoppers; Klaus Lindpaintner; Jan-Eric Litton; Andres Metspalu; Bill Ollier; Lyle J Palmer; Aarno Palotie; Markus Pasterk; Markus Perola; Peter H J Riegman; Gert-Jan van Ommen; Martin Yuille; Marianna Bledsoe; Anthony J Brookes; Isabelle Budin-Ljøsne; Paul Burton; Rex Chisholm; David Cox; Mylène Deschênes; Isabel Fortier; Pierre Hainaut; Kurt Zatloukal
Toward a roadmap in global biobanking for health.
European journal of human genetics : EJHG 2012;20(11):1105-11.
2012: Klaus Lindpaintner
Genetics research: Clinical standards not practical in the lab.
Nature 2012;483(7388):158.
2011: Bartha Maria Knoppers; Madeleine Murtagh; Paul R Burton; David Cox; Mylène Deschênes; Isabel Fortier; Jennifer R Harris; Thomas J Hudson; Jane Kaye; Klaus Lindpaintner
From genomic databases to translation: a call to action.
Journal of medical ethics 2011;37(8):515-6.
2011: Mark T Muldoon; Dale V Onisk; Meredith I Sutzko; Ann-Christine Olsson Allen; Samantha Creamer; Verapaz Gonzalez; Klaus Lindpaintner
RapidChek SELECT Salmonella enteritidis test system for the detection of Salmonella enteritidis in poultry house drag swabs, shell egg pools, and chicken carcass rinsates.
Journal of AOAC International 2011;94(4):1138-53.
2011: Klaus Lindpaintner
Biomarkers: call on industry to share.
Nature 2011;470(7333):175.
2011: Qian Zhao; Ronglin Che; Zhao Zhang; Peng Wang; Jun Li; You Li; Ke Huang; Wei Tang; Guoyin Feng; Klaus Lindpaintner; Lin He; Yongyong Shi
Positive association between GRIN2B gene and bipolar disorder in the Chinese Han Population.
Psychiatry research 2011;185(1-2):290-2.
2010: Mingqing Xu; Pak Sham; Zheng Ye; Klaus Lindpaintner; Lin He
A1166C genetic variation of the angiotensin II type I receptor gene and susceptibility to coronary heart disease: collaborative of 53 studies with 20,435 cases and 23,674 controls.
Atherosclerosis 2010;213(1):191-9.
2010: Xiaoyang Ruan; Lina Ma; Shuyu Wang; Klaus Lindpaintner; Xiangjun Liu; Binbin Wang; Zuoqi Peng; Xu Ma; Maosheng Cheng; Jinghai Zhang; Lisheng Liu; Xingyu Wang
TAQIB and I405V polymorphisms of CETP are moderately associated with obesity risk in the Chinese adult population.
Acta diabetologica 2010;47(3):217-24.
2010: Federico M Goodsaid; Shashi Amur; Jiri Aubrecht; Michael E Burczynski; Kevin Carl; Jennifer Catalano; Rosane Charlab; Sandra Close; Catherine Cornu-Artis; Laurent Essioux; Albert J Fornace; Lois Hinman; Huixiao Hong; Ian Hunt; David Jacobson-Kram; Ansar Jawaid; David Laurie; Lawrence Lesko; Heng-Hong Li; Klaus Lindpaintner; James Mayne; Peter Morrow; Marisa Papaluca-Amati; Timothy W Robison; John Roth; Ina Schuppe-Koistinen; Leming Shi; Olivia Spleiss; Weida Tong; Sharada L Truter; Jacky Vonderscher; Agnes Westelinck; Li Zhang; Issam Zineh
Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact.
Nature reviews. Drug discovery 2010;9(6):435-45.
2010: You Li; Qian Zhao; Zhao Zhang; Peng Wang; Ronglin Che; Wei Tang; Guoyin Feng; Klaus Lindpaintner; Lin He; YongYong Shi
Association study between RGS4 and bipolar disorder in the Chinese Han population.
Psychiatric genetics 2010;20(3):130-2.
2010: Bo Xi; Yue Shen; Meixian Zhang; Xin Liu; Xiaoyuan Zhao; Lijun Wu; Hong Cheng; Dongqing Hou; Klaus Lindpaintner; Lisheng Liu; Jie Mi; Xingyu Wang
The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China.
BMC medical genetics 2010;11():107.
2009: Xiaoyang Ruan; Lina Ma; Shuyu Wang; Klaus Lindpaintner; Xiangjun Liu; Binbin Wang; Zuoqi Peng; Xu Ma; Maosheng Cheng; Jinghai Zhang; Lisheng Liu; Xingyu Wang
Association of two CETP polymorphisms with HDL levels in the Chinese obese population.
Obesity (Silver Spring, Md.) 2009;17(12):2196-201.
2009: Zhao Zhang; Klaus Lindpaintner; Ronglin Che; Zangdong He; Peng Wang; Ping Yang; Guoyin Feng; Lin He; Yongyong Shi
The Val/Met functional polymorphism in COMT confers susceptibility to bipolar disorder: evidence from an association study and a meta-analysis.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(10):1193-200.
2009: Lijun Wu; Yue Shen; Xin Liu; Xu Ma; Bo Xi; Jie Mi; Klaus Lindpaintner; Xuerui Tan; Xingyu Wang
The 1425G/A SNP in PRKCH is associated with ischemic stroke and cerebral hemorrhage in a Chinese population.
Stroke; a journal of cerebral circulation 2009;40(9):2973-6.
2009: Xin Liu; Xingyu Wang; Yue Shen; Lijun Wu; Xiaoyang Ruan; Klaus Lindpaintner; Salim Yusuf; James C Engert; Sonia Anand; Xuerui Tan; Lisheng Liu
The functional variant rs1048990 in PSMA6 is associated with susceptibility to myocardial infarction in a Chinese population.
Atherosclerosis 2009;206(1):199-203.
2009: Xingwang Li; Jing Zhang; Yang Wang; Jue Ji; Fengping Yang; Chunling Wan; Peng Wang; Guoyin Feng; Klaus Lindpaintner; Lin He; Guang He
Association study on the NAPG gene and bipolar disorder in the Chinese Han population.
Neuroscience letters 2009;457(3):159-62.
2009: Zhao Zhang; You Li; Qian Zhao; Ke Huang; Peng Wang; Ping Yang; Sheng Li; Guoyin Feng; Klaus Lindpaintner; Lin He; Yongyong Shi
First evidence of association between G72 and bipolar disorder in the Chinese Han population.
Psychiatric genetics 2009;19(3):151-3.
2009: Jing Zhang; Xingwang Li; Yang Wang; Jue Ji; Fengping Yang; Guoyin Feng; Peng Wan; Klaus Lindpaintner; Lin He; Guang He
Association study on the mitochondrial gene NDUFV2 and bipolar disorder in the Chinese Han population.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(3):357-61.
2009: Xingyu Wang; Suzanne Cheng; Victoria H Brophy; Henry A Erlich; Christine Mannhalter; Klaus Berger; Wolfgang Lalouschek; Warren S Browner; Yu Shi; E Bernd Ringelstein; Christof Kessler; Jan Luedemann; Klaus Lindpaintner; Lisheng Liu; Paul M Ridker; Robert Y L Zee; Nancy R Cook
A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
Stroke; a journal of cerebral circulation 2009;40(3):683-95.
2008: Josep Grinyó; Yves Vanrenterghem; Björn Nashan; Flavio Vincenti; Henrik Ekberg; Klaus Lindpaintner; Michelle Rashford; Clare Nasmyth-Miller; Athina Voulgari; Olivia Spleiss; Matthew Truman; Laurent Essioux
Association of four DNA polymorphisms with acute rejection after kidney transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2008;21(9):879-91.
2008: Jan Monti; Judith Fischer; Svetlana Paskas; Matthias Heinig; Herbert Schulz; Claudia Gösele; Arnd Heuser; Robert Fischer; Cosima Schmidt; Alexander Schirdewan; Volkmar Gross; Oliver Hummel; Henrike Maatz; Giannino Patone; Kathrin Saar; Martin Vingron; Steven M Weldon; Klaus Lindpaintner; Bruce D Hammock; Klaus Rohde; Rainer Dietz; Stuart A Cook; Wolf-Hagen Schunck; Friedrich C Luft; Norbert Hubner
Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.
Nature genetics 2008;40(5):529-37.
2008: Robert Y L Zee; Soren Germer; Abraham Thomas; Annaswammy Raji; Brian Rhees; Paul M Ridker; Klaus Lindpaintner; Gordon H Williams; David M Nathan; Mitchell Martin
C-reactive protein gene variation and type 2 diabetes mellitus: a case-control study.
Atherosclerosis 2008;197(2):931-6.
2007: Robert Y L Zee; Suzanne Cheng; Henry A Erlich; Klaus Lindpaintner; Nader Rifai; Julie E Buring; Paul M Ridker
Intercellular adhesion molecule 1 (ICAM1) Lys56Met and Gly241Arg gene variants, plasma-soluble ICAM1 concentrations, and risk of incident cardiovascular events in 23,014 initially healthy white women.
Stroke; a journal of cerebral circulation 2007;38(12):3152-7.
2007: Qing-Ying Chen; Qi Chen; Guo-Yin Feng; Klaus Lindpaintner; Li-Jun Wang; Zheng-Xiong Chen; Zhen-Song Gao; Ji-Sheng Tang; Gang Huang; Lin He
Case-control association study of Disrupted-in-Schizophrenia-1 (DISC1) gene and schizophrenia in the Chinese population.
Journal of psychiatric research 2007;41(5):428-34.
2007: Robert Y L Zee; Samia Mora; Suzanne Cheng; Henry A Erlich; Klaus Lindpaintner; Nader Rifai; Julie E Buring; Paul M Ridker
Homocysteine, 5,10-methylenetetrahydrofolate reductase 677C>T polymorphism, nutrient intake, and incident cardiovascular disease in 24,968 initially healthy women.
Clinical chemistry 2007;53(5):845-51.
2006: Maggie C Y Ng; Larry Baum; Wing-Yee So; Vincent K L Lam; Ying Wang; Emily Poon; Brian Tomlinson; Suzanne Cheng; Klaus Lindpaintner; J C N Chan
Association of lipoprotein lipase S447X, apolipoprotein E exon 4, and apoC3 -455T>C polymorphisms on the susceptibility to diabetic nephropathy.
Clinical genetics 2006;70(1):20-8.
2006: S Christen-Zäch; M Huber; Berthold Struk; Klaus Lindpaintner; F Munier; R G Panizzon; Daniel Hohl
Pseudoxanthoma elasticum: evaluation of diagnostic criteria based on molecular data.
The British journal of dermatology 2006;155(1):89-93.
2006: Robert Y L Zee; Nancy R Cook; Suzanne Cheng; Henry A Erlich; Klaus Lindpaintner; Paul M Ridker
Polymorphism in the beta2-adrenergic receptor and lipoprotein lipase genes as risk determinants for idiopathic venous thromboembolism: a multilocus, population-based, prospective genetic analysis.
Circulation 2006;113(18):2193-200.
2006: Qing-Ying Chen; Qi Chen; Guo-Yin Feng; Chun-Ling Wan; Klaus Lindpaintner; Li-Jun Wang; Zheng-Xiong Chen; Zhen-Song Gao; Ji-Sheng Tang; Xing-Wang Li; Lin He
Association between the brain-derived neurotrophic factor (BDNF) gene and schizophrenia in the Chinese population.
Neuroscience letters 2006;397(3):285-90.
2006: Robert Y L Zee; Nancy R Cook; S Cheng; Henry A Erlich; Klaus Lindpaintner; Paul M Ridker
Multi-locus candidate gene polymorphisms and risk of myocardial infarction: a population-based, prospective genetic analysis.
Journal of thrombosis and haemostasis : JTH 2006;4(2):341-8.
2005: Sara Miksch; Amanda Lumsden; Ulf P Guenther; Dorothee Foernzler; Stéphanie Christen-Zäch; Carol Daugherty; Raj Kumar S Ramesar; Mark Lebwohl; Daniel Hohl; Kenneth H Neldner; Klaus Lindpaintner; Robert I Richards; Berthold Struk
Molecular genetics of pseudoxanthoma elasticum: type and frequency of mutations in ABCC6.
Human mutation 2005;26(3):235-48.
2005: Larry Baum; Maggie C Y Ng; Wing-Yee So; Vincent K L Lam; Ying Wang; Emily Poon; Brian Tomlinson; Suzanne Cheng; Klaus Lindpaintner; Juliana C N Chan
Effect of hepatic lipase -514C->T polymorphism and its interactions with apolipoprotein C3 -482C->T and apolipoprotein E exon 4 polymorphisms on the risk of nephropathy in chinese type 2 diabetic patients.
Diabetes care 2005;28(7):1704-9.
2005: Qing-Ying Chen; Qi Chen; Guo-Yin Feng; Klaus Lindpaintner; Yi Chen; Xiaodong Sun; Zhengxiong Chen; Zhensong Gao; Jisheng Tang; Lin He
Case-control association study of the close homologue of L1 (CHL1) gene and schizophrenia in the Chinese population.
Schizophrenia research 2005;73(2-3):269-74.
2005: Tianhua Niu; Adam A Ding; Reinhold Kreutz; Klaus Lindpaintner
An expectation-maximization-likelihood-ratio test for handling missing data: application in experimental crosses.
Genetics 2005;169(2):1021-31.
2005: Klaus Lindpaintner
Pharmacogenetics and pharmacogenomics.
Methods in molecular medicine 2005;108():235-60.
2004: Martin Spiecker; Harald Darius; Thomas Hankeln; Muhidien Soufi; Alexander M Sattler; Juergen R Schaefer; Koichi Node; Jan Börgel; Andreas Mügge; Klaus Lindpaintner; Anika Huesing; Bernhard Maisch; Darryl C Zeldin; James K Liao
Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2.
Circulation 2004;110(15):2132-6.
2004: Robert Y L Zee; Hillary H Hegener; Arturo Fernandez-Cruz; Klaus Lindpaintner
C-reactive protein gene polymorphisms and the incidence of post-angioplasty restenosis.
Atherosclerosis 2004;176(2):393-6.
2004: Alasdair Breckenridge; Klaus Lindpaintner; Peter Lipton; howard mcleod; Mark Rothstein; Helen Wallace
Pharmacogenetics: ethical problems and solutions.
Nature reviews. Genetics 2004;5(9):676-80.
2004: Wan Ji; Wenli Zhou; Keqin Gregg; Klaus Lindpaintner; Sara Davis; Scott Davis
A method for gene expression analysis by oligonucleotide arrays from minute biological materials.
Analytical biochemistry 2004;331(2):329-39.
2004: Robert Y L Zee; Nancy R Cook; Suzanne Cheng; Henry A Erlich; Klaus Lindpaintner; Richard T Lee; Paul M Ridker
Threonine for alanine substitution in the eotaxin (CCL11) gene and the risk of incident myocardial infarction.
Atherosclerosis 2004;175(1):91-4.
2004: Richard A Gibbs; George M Weinstock; Michael L Metzker; Donna M Muzny; Erica J Sodergren; Steven Scherer; Graham Scott; David Steffen; Kim C Worley; Paula E Burch; Geoffrey Okwuonu; Sandra Hines; Lora Lewis; Christine DeRamo; Oliver Delgado; Shannon Dugan-Rocha; George Miner; Margaret Morgan; Alicia Hawes; Rachel Gill; Robert A Holt; Mark D Adams; Peter G Amanatides; Holly Baden-Tillson; Mary Barnstead; Soo Chin; Cheryl A Evans; Steve Ferriera; Carl Fosler; Anna Glodek; Zhiping Gu; Don Jennings; Cheryl L Kraft; Trixie Nguyen; Cynthia M Pfannkoch; Cynthia Sitter; Granger G Sutton; J Craig Venter; Trevor Woodage; Douglas Smith; Hong-Mei Lee; Erik Gustafson; Patrick Cahill; Arnold Kana; Lynn Doucette-Stamm; Keith Weinstock; Kim Fechtel; Robert B Weiss; Diane M Dunn; Eric Green; Robert W Blakesley; Gerard G Bouffard; Pieter J De Jong; Kazutoyo Osoegawa; Baoli Zhu; Marco Marra; Jacqueline Schein; Ian Bosdet; Chris Fjell; Steven Jones; Martin Krzywinski; Carrie Mathewson; Asim Siddiqui; Natasja Wye; John McPherson; Shaying Zhao; Claire M Fraser-Liggett; Jyoti Shetty; Sofiya Shatsman; Keita Geer; Yixin Chen; Sofyia Abramzon; William C Nierman; Paul H Havlak; Rui Chen; K James Durbin; Amy Egan; Yanru Ren; Xing-Zhi Song; Bingshan Li; Yue Liu; Xiang Qin; Simon Cawley; Kim C Worley; A J Cooney; Lisa M D'Souza; Kirt Martin; Jia Qian Wu; Manuel Gonzalez-Garay; Andrew R Jackson; Kenneth J Kalafus; Michael P McLeod; Aleksandar Milosavljevic; Davinder Virk; Andrei Volkov; David A Wheeler; Zhengdong D Zhang; Jeffrey A Bailey; Evan E Eichler; Eray Tuzun; Ewan Birney; Emmanuel Mongin; Abel Ureta-Vidal; Cara Woodwark; Evgeny Zdobnov; Peer Bork; Mikita Suyama; David Torrents; Marina Alexandersson; Barbara J Trask; Janet M Young; Hui Huang; Huajun Wang; Heming Xing; Sue Daniels; Darryl Gietzen; Jeanette Schmidt; Kristian Stevens; Ursula Vitt; Jim Wingrove; Francisco Camara; M Mar Albà; Josep F Abril; Roderic Guigo; Arian Smit; Inna Dubchak; Edward M Rubin; Olivier Couronne; Alexander Poliakov; Norbert Hübner; Detlev Ganten; Claudia Goesele; Oliver Hummel; Thomas Kreitler; Young-Ae Lee; Jan Monti; Herbert Schulz; Heike Zimdahl; Heinz Himmelbauer; Hans Lehrach; Howard J Jacob; Susan Bromberg; Jo Gullings-Handley; Michael I Jensen-Seaman; Anne E Kwitek; Jozef Lazar; Dean Pasko; Peter Tonellato; Simon Twigger; Chris P Ponting; Jose M Duarte; Stephen Rice; Leo Goodstadt; Scott A Beatson; Richard Emes; Eitan E Winter; Caleb Webber; Petra Brandt; Gerald Nyakatura; Margaret Adetobi; Francesca Chiaromonte; Laura Elnitski; Pallavi Eswara; Ross C Hardison; Minmei Hou; Diana Kolbe; Kateryna Makova; Webb Miller; Anton Nekrutenko; Cathy Riemer; Scott Schwartz; James TAYLOR; Shan Yang; Yi Zhang; Klaus Lindpaintner; T Dan Andrews; Mario Caccamo; Michele Clamp; Laura Clarke; Valerie Curwen; Richard Durbin; Eduardo Eyras; Stephen M Searle; Gregory Cooper; Serafim Batzoglou; Michael Brudno; Arend Sidow; Eric A Stone; J Craig Venter; Bret Payseur; Guillaume Bourque; Carlos López-Otín; Xose S Puente; Kushal Chakrabarti; Sourav Chatterji; Colin Dewey; Lior Pachter; Nicolas Bray; Von Bing Yap; Anat Caspi; Glenn Tesler; Pavel A Pevzner; David Haussler; Krishna M Roskin; Robert Baertsch; Hiram Clawson; Terrence S Furey; Angie S Hinrichs; Donna Karolchik; W James Kent; Kate R Rosenbloom; Heather Trumbower; Matt Weirauch; David N Cooper; Peter D Stenson; Bin Ma; Michael Brent; Manimozhiyan Arumugam; David Shteynberg; Richard R Copley; Martin Taylor; Harold Riethman; Uma Mudunuri; Jane Peterson; Mark Guyer; Adam Felsenfeld; Susan Old; Stephen Mockrin; Francis S Collins
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Nature 2004;428(6982):493-521.
2004: Maggie C Y Ng; Ying Wang; Wing-Yee So; Suzanne Cheng; Sophie Visvikis; Robert Y L Zee; Arturo Fernandez-Cruz; Klaus Lindpaintner; Juliana C N Chan
Ethnic differences in the linkage disequilibrium and distribution of single-nucleotide polymorphisms in 35 candidate genes for cardiovascular diseases.
Genomics 2004;83(4):559-65.
2004: Martin D Tobin; Peter Braund; Paul R Burton; John R Thompson; Richard Steeds; Kevin Channer; Suzanne Cheng; Klaus Lindpaintner; Nilesh J Samani
Genotypes and haplotypes predisposing to myocardial infarction: a multilocus case-control study.
European heart journal 2004;25(6):459-67.
2004: Caroline S Fox; Martin G Larson; Diane Corey; DaLi Feng; Klaus Lindpaintner; Joseph F Polak; Philip A Wolf; Ralph B D'Agostino; Geoffrey H Tofler; Christopher J O'Donnell
Absence of association between polymorphisms in the hemostatic factor pathway genes and carotid intimal medial thickness: the Framingham Heart Study.
Stroke; a journal of cerebral circulation 2004;35(3):e65-7.
2004: Robert Y L Zee; Nancy R Cook; Chung-Ah Kim; Arturo Fernandez-Cruz; Klaus Lindpaintner
TP53 haplotype-based analysis and incidence of post-angioplasty restenosis.
Human genetics 2004;114(4):386-90.
2004: Robert Y L Zee; Nancy R Cook; Suzanne Cheng; Rebecca Reynolds; Henry A Erlich; Klaus Lindpaintner; Paul M Ridker
Polymorphism in the P-selectin and interleukin-4 genes as determinants of stroke: a population-based, prospective genetic analysis.
Human molecular genetics 2004;13(4):389-96.
2003: Robert Y L Zee; Antonio Fernandez-Ortiz; Carlos Macaya; Emilio Pintor; Arturo Fernandez-Cruz; Klaus Lindpaintner
IL-1 cluster genes and occurrence of post-percutaneous transluminal coronary angioplasty restenosis: a prospective, angiography-based evaluation.
Atherosclerosis 2003;171(2):259-64.
2003: Klaus Lindpaintner
[Pharmacogenetics: forerunner for individualized medicine].
Therapeutische Umschau. Revue thérapeutique 2003;60(8):487-92.
2003: Lei Jiang; Klaus Lindpaintner; H-F Li; Niu-Fan Gu; H Langen; Lin He; M Fountoulakis
Proteomic analysis of the cerebrospinal fluid of patients with schizophrenia.
Amino acids 2003;25(1):49-57.
2003: Robert Y L Zee; A Fernandez-Otiz; Carlos Macaya; Emilio Pintor; Klaus Lindpaintner; Arturo Fernandez-Cruz
Lipid metabolism and occurrence of post-percutaneous transluminal coronary angioplasty restenosis: role of cholesteryl ester transfer protein and paraoxonase/arylesterase.
Journal of thrombosis and haemostasis : JTH 2003;1(6):1202-7.
2003: Paul M Ridker; Nancy R Cook; Suzanne Cheng; Henry A Erlich; Klaus Lindpaintner; Jorge Plutzky; Robert Y L Zee
Alanine for proline substitution in the peroxisome proliferator-activated receptor gamma-2 (PPARG2) gene and the risk of incident myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(5):859-63.
2003: Qiong Yang; Geoffrey H Tofler; L Adrienne Cupples; Martin G Larson; DaLi Feng; Klaus Lindpaintner; Daniel Levy; Ralph B D'Agostino; Christopher J O'Donnell
A genome-wide search for genes affecting circulating fibrinogen levels in the Framingham Heart Study.
Thrombosis research 2003;110(1):57-64.
2003: Klaus Lindpaintner
Pharmacogenetics and pharmacogenomics in drug discovery and development: an overview.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2003;41(4):398-410.
2003: Klaus Lindpaintner
Pharmacogenetics and the future of medical practice.
Journal of molecular medicine (Berlin, Germany) 2003;81(3):141-53.
2003: Yaning Yang; Josephine Hoh; Clemens Broger; Martin Neeb; Joanne Edington; Klaus Lindpaintner; Jurg Ott
Statistical methods for analyzing microarray feature data with replications.
Journal of computational biology : a journal of computational molecular cell biology 2003;10(2):157-69.
2002: Klaus Lindpaintner
The importance of being modest--reflections on the pharmacogenetics of abacavir.
Pharmacogenomics 2002;3(6):835-8.
2002: Wendy Balemans; Dorothee Foernzler; C Parsons; M Ebeling; A Thompson; D M Reid; Klaus Lindpaintner; Stuart H Ralston; Wim Van Hul
Lack of association between the SOST gene and bone mineral density in perimenopausal women: analysis of five polymorphisms.
Bone 2002;31(4):515-9.
2002: Klaus Lindpaintner
Pharmacogenetics and the future of medical practice.
British journal of clinical pharmacology 2002;54(2):221-30.
2002: Klaus Lindpaintner
The impact of pharmacogenetics and pharmacogenomics on drug discovery.
Nature reviews. Drug discovery 2002;1(6):463-9.
2002: Wan Ji; Matthew B Wright; Li Cai; Angel Flament; Klaus Lindpaintner
Efficacy of SSH PCR in isolating differentially expressed genes.
BMC genomics 2002;3():12.
2002: Simin Liu; Christian Schmitz; Meir J Stampfer; Frank Sacks; Charles H Hennekens; Klaus Lindpaintner; Paul M Ridker; Simm Liu
A prospective study of TaqIB polymorphism in the gene coding for cholesteryl ester transfer protein and risk of myocardial infarction in middle-aged men.
Atherosclerosis 2002;161(2):469-74.
2002: Solveig Gretarsdottir; Sigurlaug Sveinbjörnsdottir; Hjortur H Jonsson; Finnbogi Jakobsson; Elisabet Einarsdottir; Uggi Agnarsson; Dana L Shkolny; Gudmundur Vikar Einarsson; Herdis M Gudjonsdottir; Einar M Valdimarsson; Olafur B Einarsson; Gudmundur Thorgeirsson; Radinka Hadzic; Sif Jonsdottir; Sigridur Th Reynisdottir; Sigrun M Bjarnadottir; Thorunn Gudmundsdottir; Gudrun J Gudlaugsdottir; Ramanjit Gill; Klaus Lindpaintner; Jesus Sainz; Helgi Hermann Hannesson; Gunnar Sigurdsson; Michael L Frigge; Augustine Kong; Vilmundur Gudnason; Kari Stefansson; Jeffrey R Gulcher
Localization of a susceptibility gene for common forms of stroke to 5q12.
American journal of human genetics 2002;70(3):593-603.
2002: Gudmundur Gudmundsson; Stefan Matthiasson; Haukur Arason; Halldor Johannsson; Freyr Runarsson; Hjördis Bjarnason; Katrin Helgadottir; Steinthora Thorisdottir; Gudrun Ingadottir; Klaus Lindpaintner; Jesus Sainz; Vilmundur Gudnason; Michael L Frigge; Augustine Kong; Jeffrey R Gulcher; Kari Stefansson
Localization of a gene for peripheral arterial occlusive disease to chromosome 1p31.
American journal of human genetics 2002;70(3):586-92.
2002: Wendy Balemans; N Patel; M Ebeling; Els Van Hul; Wim Wuyts; C Lacza; M Dioszegi; Frederik G Dikkers; P Hildering; Patrick J Willems; Joke B G M Verheij; Klaus Lindpaintner; B Vickery; Dorothee Foernzler; Wim Van Hul
Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease.
Journal of medical genetics 2002;39(2):91-7.
2002: Gonzalo Acuña; Dorothee Foernzler; Diane Leong; Michael Rabbia; Ralf Smit; Ernest Dorflinger; Rodolfo Gasser; Josephine Hoh; Jürg Ott; Edilio Borroni; Zung To; Annick Thompson; Jia Li; Lara Hashimoto; Klaus Lindpaintner
Pharmacogenetic analysis of adverse drug effect reveals genetic variant for susceptibility to liver toxicity.
The pharmacogenomics journal 2002;2(5):327-34.
2002: Robert Y L Zee; J Hoh; S Cheng; R Reynolds; Michael A Grow; A Silbergleit; K Walker; L Steiner; G Zangenberg; Antonio Fernandez-Ortiz; Carlos Macaya; Emilio Pintor; Arturo Fernandez-Cruz; J Ott; Klaus Lindpaintner
Multi-locus interactions predict risk for post-PTCA restenosis: an approach to the genetic analysis of common complex disease.
The pharmacogenomics journal 2002;2(3):197-201.
2002: Klaus Lindpaintner
Pharmacogenetics and the future of medical practice.
Clinical laboratory 2002;48(5-6):335-45.
2002: Robert Y L Zee; S D Solomon; Umed Ajani; M A Pfeffer; Klaus Lindpaintner
A prospective evaluation of the angiotensin-converting enzyme D/I polymorphism and left ventricular remodeling in the 'Healing and Early Afterload Reducing Therapy' study.
Clinical genetics 2002;61(1):21-5.
2001: G J Blake; C Schmitz; Klaus Lindpaintner; P M Ridker
Mutation in the promoter region of the beta-fibrinogen gene and the risk of future myocardial infarction, stroke and venous thrombosis.
European heart journal 2001;22(24):2262-6.
2001: Robert Y L Zee; K Lunze; Klaus Lindpaintner; Paul M Ridker
A prospective evaluation of the interleukin-1 receptor antagonist intron 2 gene polymorphism and the risk of myocardial infarction.
Thrombosis and haemostasis 2001;86(5):1141-3.
2001: Y Zhao; L Y Ma; Y X Liu; X Y Wang; L S Liu; Klaus Lindpaintner
[Relationship between alpha-ENaC gene Thr663Ala polymorphism and ischemic stroke].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 2001;23(5):499-501.
2001: L Cai; Amanda Lumsden; U P Guenther; S A Neldner; S Zäch; H Knoblauch; Raj Kumar S Ramesar; Daniel Hohl; David F Callen; Kenneth H Neldner; Klaus Lindpaintner; Robert I Richards; Berthold Struk
A novel Q378X mutation exists in the transmembrane transporter protein ABCC6 and its pseudogene: implications for mutation analysis in pseudoxanthoma elasticum.
Journal of molecular medicine (Berlin, Germany) 2001;79(9):536-46.
2001: D Feng; Klaus Lindpaintner; Martin G Larson; Christopher J O'Donnell; Izabella Lipinska; Patrice Sutherland; Murray A Mittleman; James E Muller; Ralph B D'Agostino; Daniel Levy; Geoffrey H Tofler
Platelet glycoprotein IIIa Pl(a) polymorphism, fibrinogen, and platelet aggregability: The Framingham Heart Study.
Circulation 2001;104(2):140-4.
2001: Christopher J O'Donnell; Martin G Larson; D Feng; Patrice Sutherland; Klaus Lindpaintner; Richard H Myers; R A D'Agostino; Daniel Levy; Geoffrey H Tofler
Genetic and environmental contributions to platelet aggregation: the Framingham heart study.
Circulation 2001;103(25):3051-6.
2001: Robert Y L Zee; Antonio Fernandez-Ortiz; C Macaya; Emilio Pintor; Klaus Lindpaintner; Arturo Fernandez-Cruz
Ace D/I polymorphism and incidence of post-PTCA restenosis: a prospective, angiography-based evaluation.
Hypertension 2001;37(3):851-5.
2001: Wendy Balemans; M Ebeling; N Patel; Els Van Hul; P Olson; M Dioszegi; C Lacza; Wim Wuyts; Jenneke van den Ende; P Willems; A F Paes-Alves; S Hill; M Bueno; F J Ramos; P Tacconi; Frederik G Dikkers; Constantine Straturis; Klaus Lindpaintner; B Vickery; Dorothee Foernzler; Wim Van Hul
Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST).
Human molecular genetics 2001;10(5):537-43.
2001: R Y Zee; Klaus Lindpaintner; Berthold Struk; C H Hennekens; Paul M Ridker
A prospective evaluation of the CD14 C(-260)T gene polymorphism and the risk of myocardial infarction.
Atherosclerosis 2001;154(3):699-702.
2001: Bruna Gigante; Speranza Rubattu; R Y Zee; M Volpe; Klaus Lindpaintner
Non-random chromosomal distribution of SSLPs: systematic assessment using a novel genetic linkage map between two closely related rat strains.
Cytogenetics and cell genetics 2001;95(1-2):64-72.
2001: Klaus Lindpaintner
Pharmacogenetics and the future of medical practice: conceptual considerations.
The pharmacogenomics journal 2001;1(1):23-6.
2001: T Niu; Berthold Struk; Klaus Lindpaintner
Statistical considerations for genome-wide scans: design and application of a novel software package POLYMORPHISM.
Human heredity 2001;52(2):102-9.
2000: R Y Zee; Richard H Myers; M T Hannan; P W Wilson; Jose Ordovas; Ernst Schaefer; Klaus Lindpaintner; D P Kiel
Absence of linkage for bone mineral density to chromosome 12q12-14 in the region of the vitamin D receptor gene.
Calcified tissue international 2000;67(6):434-9.
2000: Claudia Gösele; L Hong; Thomas Kreitler; M Rossmann; B Hieke; U Gross; M Kramer; Heinz Himmelbauer; M T Bihoreau; AE Kwitek-Black; Simon N Twigger; Peter Tonellato; H J Jacob; Leonard C Schalkwyk; Klaus Lindpaintner; Detlev Ganten; Hans Lehrach; Margit Knoblauch
High-throughput scanning of the rat genome using interspersed repetitive sequence-PCR markers.
Genomics 2000;69(3):287-94.
2000: Josephine Hoh; Anja Wille; Robert Y L Zee; S Cheng; R Reynolds; Klaus Lindpaintner; Jurg Ott
Selecting SNPs in two-stage analysis of disease association data: a model-free approach.
Annals of human genetics 2000;64(Pt 5):413-7.
2000: D Feng; Geoffrey H Tofler; Martin G Larson; Christopher J O'Donnell; Izabella Lipinska; C Schmitz; Patrice Sutherland; M T Johnstone; James E Muller; Ralph B D'Agostino; Daniel Levy; Klaus Lindpaintner
Factor VII gene polymorphism, factor VII levels, and prevalent cardiovascular disease: the Framingham Heart Study.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):593-600.
2000: W Ji; L Cai; M B Wright; G Walker; P Salgam; Axel Vater; Klaus Lindpaintner
Preservation of gene expression ratios among multiple complex cDNAs after PCR amplification: application to differential gene expression studies.
Journal of structural and functional genomics 2000;1(1):1-7.
2000: L Cai; Klaus Lindpaintner; J Browne; Frank Gruetzner; Thomas Haaf; Michael R James; Marie-Thérèse Bihoreau
An anchored YAC-STS framework for the rat genome.
Cytogenetics and cell genetics 2000;89(3-4):168-70.
2000: Berthold Struk; L Cai; S Zäch; W Ji; J Chung; Amanda Lumsden; M Stumm; M Huber; L Schaen; C A Kim; lowell goldsmith; D Viljoen; Luis Figuera; W Fuchs; F Munier; Raj Kumar S Ramesar; Daniel Hohl; R Richards; Kenneth H Neldner; Klaus Lindpaintner
Mutations of the gene encoding the transmembrane transporter protein ABC-C6 cause pseudoxanthoma elasticum.
Journal of molecular medicine (Berlin, Germany) 2000;78(5):282-6.
1999: Speranza Rubattu; M A Lee-Kirsch; P DePaolis; Rosangela Giliberti; Bruna Gigante; A Lombardi; Massimo Volpe; Klaus Lindpaintner
Altered structure, regulation, and function of the gene encoding the atrial natriuretic peptide in the stroke-prone spontaneously hypertensive rat.
Circulation research 1999;85(10):900-5.
1999: S Rubattu; Paul M Ridker; Meir J Stampfer; M Volpe; Charles H Hennekens; Klaus Lindpaintner
The gene encoding atrial natriuretic peptide and the risk of human stroke.
Circulation 1999;100(16):1722-6.
1999: Norbert Hübner; Y A Lee; Klaus Lindpaintner; Detlev Ganten; Reinhold Kreutz
Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1.
Hypertension 1999;34(4 Pt 1):643-8.
1999: Tianhua Niu; Xiping Xu; H J Cordell; John J Rogus; Y Zhou; Zhian Fang; Klaus Lindpaintner
Linkage analysis of candidate genes and gene-gene interactions in chinese hypertensive sib pairs.
Hypertension 1999;33(6):1332-7.
1999: O Costerousse; Klaus Lindpaintner; Martin Paul; D Ganten; R Kreutz
Interstrain differences in angiotensin I-converting enzyme mRNA and activity levels. Comparison between stroke-prone spontaneously hypertensive rats and Wistar-Kyoto rats.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1999;21(4):377-93.
1999: D Feng; Klaus Lindpaintner; Martin G Larson; V S Rao; Christopher J O'Donnell; Izabella Lipinska; C Schmitz; Patrice Sutherland; H Silbershatz; Ralph B D'Agostino; James E Muller; Richard H Myers; Daniel Levy; Geoffrey H Tofler
Increased platelet aggregability associated with platelet GPIIIa PlA2 polymorphism: the Framingham Offspring Study.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(4):1142-7.
1999: M A Lee-Kirsch; F Gaudet; M C Cardoso; Klaus Lindpaintner
Distinct renin isoforms generated by tissue-specific transcription initiation and alternative splicing.
Circulation research 1999;84(2):240-6.
1999: Margit Knoblauch; Klaus Lindpaintner
Use of animal models to search for candidate genes associated with essential hypertension.
Current hypertension reports 1999;1(1):25-30.
1999: Tianhua Niu; Jianhua Yang; Binyan Wang; W Chen; Z Wang; N Laird; E Wei; Zhian Fang; Klaus Lindpaintner; John J Rogus; Xiping Xu
Angiotensinogen gene polymorphisms M235T/T174M: no excess transmission to hypertensive Chinese.
Hypertension 1999;33(2):698-702.
1999: Robert Y L Zee; Paul M Ridker; Meir J Stampfer; Charles H Hennekens; Klaus Lindpaintner
Prospective evaluation of the angiotensin-converting enzyme insertion/deletion polymorphism and the risk of stroke.
Circulation 1999;99(3):340-3.
1999: Klaus Lindpaintner
Genetics in drug discovery and development: challenge and promise of individualizing treatment in common complex diseases.
British medical bulletin 1999;55(2):471-91.
1998: Christopher J O'Donnell; Klaus Lindpaintner; Martin G Larson; V S Rao; Jose Ordovas; Ernst Schaefer; Richard H Myers; Daniel Levy
Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study.
Circulation 1998;97(18):1766-72.
1998: Robert Y L Zee; V S Rao; RZ Paster; C S Sweet; Klaus Lindpaintner
Three candidate genes and angiotensin-converting enzyme inhibitor-related cough: a pharmacogenetic analysis.
Hypertension 1998;31(4):925-8.
1998: Chana Yagil; Marina Sapojnikov; Reinhold Kreutz; G Katni; Klaus Lindpaintner; Detlev Ganten; Yoram Yagil
Salt susceptibility maps to chromosomes 1 and 17 with sex specificity in the Sabra rat model of hypertension.
Hypertension 1998;31(1):119-24.
1998: Tianhua Niu; Xiping Xu; John J Rogus; Y Zhou; Chanzhong Chen; Jianhua Yang; Zhian Fang; C Schmitz; J Zhao; V S Rao; Klaus Lindpaintner
Angiotensinogen gene and hypertension in Chinese.
The Journal of clinical investigation 1998;101(1):188-94.
1997: Massimo Volpe; Bruna Gigante; I Enea; Antonio Porcellini; R Russo; M A Lee; P Magri; Gianluigi Condorelli; Carmine Savoia; Klaus Lindpaintner; Speranza Rubattu
Role of tissue renin in the regulation of aldosterone biosynthesis in the adrenal cortex of nephrectomized rats.
Circulation research 1997;81(5):857-64.
1997: Berthold Struk; Kenneth H Neldner; V S Rao; P St Jean; Klaus Lindpaintner
Mapping of both autosomal recessive and dominant variants of pseudoxanthoma elasticum to chromosome 16p13.1.
Human molecular genetics 1997;6(11):1823-8.
1997: M A Lee; L Cai; Norbert Hübner; Y A Lee; Klaus Lindpaintner
Tissue- and development-specific expression of multiple alternatively spliced transcripts of rat neuronal nitric oxide synthase.
The Journal of clinical investigation 1997;100(6):1507-12.
1997: K X Chai; VC Chen; Aiguo Ni; Klaus Lindpaintner; S Rubattu; Lee Chao; Julie Chao
Molecular cloning and expression of rat kallistatin gene.
Biochimica et biophysica acta 1997;1353(3):277-86.
1997: Reinhold Kreutz; Berthold Struk; P Stock; Norbert Hübner; D Ganten; Klaus Lindpaintner
Evidence for primary genetic determination of heart rate regulation: chromosomal mapping of a genetic locus in the rat.
Circulation 1997;96(4):1078-81.
1997: Klaus Lindpaintner
Genetics of interventional cardiology. Old principles, new frontiers.
Circulation 1997;96(1):12-4.
1997: Michael R James; Klaus Lindpaintner
Why map the rat?
Trends in genetics : TIG 1997;13(5):171-3.
1997: Marie-Thérèse Bihoreau; Dominique Gauguier; N Kato; G Hyne; Klaus Lindpaintner; John P Rapp; Michael R James; G Mark Lathrop
A linkage map of the rat genome derived from three F2 crosses.
Genome research 1997;7(5):434-40.
1997: EO Weinberg; M A Lee; M Weigner; Klaus Lindpaintner; S P Bishop; C R Benedict; Kalon K L Ho; Pamela S Douglas; E Chafizadeh; Beverly H Lorell
Angiotensin AT1 receptor inhibition. Effects on hypertrophic remodeling and ACE expression in rats with pressure-overload hypertrophy due to ascending aortic stenosis.
Circulation 1997;95(6):1592-600.
1997: C Schmitz; Klaus Lindpaintner
Two specific and simple methods for genotyping of the paraoxonase/arylesterase A/B polymorphism.
Genetic analysis : biomolecular engineering 1997;14(1):9-11.
1997: Paul M Ridker; Charles H Hennekens; C Schmitz; Meir J Stampfer; Klaus Lindpaintner
PIA1/A2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis.
Lancet 1997;349(9049):385-8.
1997: L Cai; L C Schalkwyk; A Schoeberlein-Stehli; Robert Y L Zee; A Smith; Thomas Haaf; M Georges; H Lehrach; Klaus Lindpaintner
Construction and characterization of a 10-genome equivalent yeast artificial chromosome library for the laboratory rat, Rattus norvegicus.
Genomics 1997;39(3):385-92.
1997: Paul M Ridker; Charles H Hennekens; Klaus Lindpaintner; Meir J Stampfer; J P Miletich
Arterial and venous thrombosis is not associated with the 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor gene in a large cohort of US men.
Circulation 1997;95(1):59-62.
1997: S Rubattu; M Volpe; V Raman; Klaus Lindpaintner
[The cardiac renin-angiotensin system and its role in ventricular hypertrophy associated with arterial hypertension].
Cardiologia (Rome, Italy) 1997;42(1):47-50.
1997: Reinhold Kreutz; Berthold Struk; S Rubattu; Norbert Hübner; J Szpirer; Claude Szpirer; Detlev Ganten; Klaus Lindpaintner
Role of the alpha-, beta-, and gamma-subunits of epithelial sodium channel in a model of polygenic hypertension.
Hypertension 1997;29(1 Pt 1):131-6.
1997: Roberto Pedrinelli; Klaus Lindpaintner; Giulia Dell'Omo; Vinicio Napoli; V Di Bello; Raffaele De Caterina; Roberto Petrucci
Urinary albumin excretion and atherosclerosis in essential hypertension.
Clinical science (London, England : 1979) 1997;92(1):45-50.
1996: N J Schork; S P Nath; Klaus Lindpaintner; Howard J Jacob
Extensions to quantitative trait locus mapping in experimental organisms.
Hypertension 1996;28(6):1104-11.
1996: James S Clark; B Jeffs; A O Davidson; W K Lee; Niall H Anderson; M T Bihoreau; M Julia Brosnan; AM Devlin; andrew william kelman; Klaus Lindpaintner; Anna F Dominiczak
Quantitative trait loci in genetically hypertensive rats. Possible sex specificity.
Hypertension 1996;28(5):898-906.
1996: Reinhold Kreutz; P Stock; Berthold Struk; Klaus Lindpaintner
The Y chromosome. Epistatic and ecogenetic interactions in genetic hypertension.
Hypertension 1996;28(5):895-7.
1996: C Schmitz; Klaus Lindpaintner; P Verhoef; J Michael Gaziano; Julie E Buring
Genetic polymorphism of methylenetetrahydrofolate reductase and myocardial infarction. A case-control study.
Circulation 1996;94(8):1812-4.
1996: Chana Yagil; G Katni; Speranza Rubattu; C Stolpe; Reinhold Kreutz; Klaus Lindpaintner; Detlev Ganten; D Ben-Ishay; Yoram Yagil
Development, genotype and phenotype of a new colony of the Sabra hypertension prone (SBH/y) and resistant (SBN/y) rat model of slat sensitivity and resistance.
Journal of hypertension 1996;14(10):1175-82.
1996: Y A Lee; C S Liang; M A Lee; Klaus Lindpaintner
Local stress, not systemic factors, regulate gene expression of the cardiac renin-angiotensin system in vivo: a comprehensive study of all its components in the dog.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):11035-40.
1996: Speranza Rubattu; M Volpe; Reinhold Kreutz; U Ganten; D Ganten; Klaus Lindpaintner
Chromosomal mapping of quantitative trait loci contributing to stroke in a rat model of complex human disease.
Nature genetics 1996;13(4):429-34.
1996: Massimo Volpe; guido iaccarino; Carmine Vecchione; D Rizzoni; R Russo; Speranza Rubattu; G Condorelli; U Ganten; D Ganten; Bruno Trimarco; Klaus Lindpaintner
Association and cosegregation of stroke with impaired endothelium-dependent vasorelaxation in stroke prone, spontaneously hypertensive rats.
The Journal of clinical investigation 1996;98(2):256-61.
1996: Klaus Lindpaintner; M Lee; M G Larson; V S Rao; Marc A Pfeffer; Jose Ordovas; Ernst Schaefer; A F Wilson; P W Wilson; R S Vasan; Richard H Myers; D Levy
Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass.
The New England journal of medicine 1996;334(16):1023-8.
1995: Speranza Rubattu; Berthold Struk; Reinhold Kreutz; M Volpe; Klaus Lindpaintner
Animal models of genetic hypertension: what can we learn for human hypertension?
Clinical and experimental pharmacology & physiology 1995;22(12):S386-93.
1995: Paul M Ridker; J P Miletich; Meir J Stampfer; Samuel Z Goldhaber; Klaus Lindpaintner; Charles H Hennekens
Factor V Leiden and risks of recurrent idiopathic venous thromboembolism.
Circulation 1995;92(10):2800-2.
1995: V K Raman; Y A Lee; Klaus Lindpaintner
The cardiac renin-angiotensin-aldosterone system and hypertensive cardiac hypertrophy.
The American journal of cardiology 1995;76(13):18D-23D.
1995: Reinhold Kreutz; Norbert Hübner; Detlev Ganten; Klaus Lindpaintner
Genetic linkage of the ACE gene to plasma angiotensin-converting enzyme activity but not to blood pressure. A quantitative trait locus confers identical complex phenotypes in human and rat hypertension.
Circulation 1995;92(9):2381-4.
1995: Norbert Hübner; Reinhold Kreutz; Speranza Rubattu; Y A Lee; Detlev Ganten; P D Allen; Klaus Lindpaintner
The gene encoding endothelial nitric oxide synthase, Nos3, maps to rat chromosome 4.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(10):758-9.
1995: Reinhold Kreutz; Norbert Hübner; M R James; Marie-Thérèse Bihoreau; Dominique Gauguier; G M Lathrop; Detlev Ganten; Klaus Lindpaintner
Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(19):8778-82.
1995: Norbert Hübner; Reinhold Kreutz; S Takahashi; Detlev Ganten; Klaus Lindpaintner
Altered angiotensinogen amino acid sequence and plasma angiotensin II levels in genetically hypertensive rats. A study on cause and effect.
Hypertension 1995;26(2):279-84.
1995: Klaus Lindpaintner; M A Pfeffer
Molecular genetics crying wolf? The case of the angiotensin-converting enzyme gene and cardiovascular disease.
Journal of the American College of Cardiology 1995;25(7):1632-3.
1995: Paul M Ridker; Charles H Hennekens; Klaus Lindpaintner; Meir J Stampfer; P R Eisenberg; J P Miletich
Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men.
The New England journal of medicine 1995;332(14):912-7.
1995: Klaus Lindpaintner; Marc A Pfeffer; R Kreutz; Meir J Stampfer; F Grodstein; F LaMotte; Julie E Buring; Charles H Hennekens
A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease.
The New England journal of medicine 1995;332(11):706-11.
1995: Klaus Lindpaintner
Finding an obesity gene--a tale of mice and man.
The New England journal of medicine 1995;332(10):679-80.
1994: Klaus Lindpaintner; R Kreutz
Caveat emptor.
Hypertension 1994;24(3):251-3; discussion 254.
1994: Klaus Lindpaintner
Genes, hypertension, and cardiac hypertrophy.
The New England journal of medicine 1994;330(23):1678-9.
1994: Norbert Hübner; Reinhold Kreutz; S Takahashi; Detlev Ganten; Klaus Lindpaintner
Unlike human hypertension, blood pressure in a hereditary hypertensive rat strain shows no linkage to the angiotensinogen locus.
Hypertension 1994;23(6 Pt 1):797-801.
1994: Klaus Lindpaintner
What can the molecular genetics of hypertensive rats teach us about the genetics of hypertension in humans?
Current opinion in nephrology and hypertension 1994;3(1):30-8.
1993: Y A Lee; Klaus Lindpaintner
Role of the cardiac renin-angiotensin system in hypertensive cardiac hypertrophy.
European heart journal 1993;14 Suppl J():42-8.
1993: Klaus Lindpaintner
Blood pressure and heredity. Is it all in the genes, or not?
Hypertension 1993;22(2):147-9.
1993: Diomedes E Logothetis; B F Kammen; Klaus Lindpaintner; D Bisbas; B Nadal-Ginard
Gating charge differences between two voltage-gated K+ channels are due to the specific charge content of their respective S4 regions.
Neuron 1993;10(6):1121-9.
1993: Y A Lee; Klaus Lindpaintner
The cardiac renin-angiotensin system. From basic research to clinical relevance.
Arzneimittel-Forschung 1993;43(2A):201-6.
1993: Klaus Lindpaintner; W Lu; N Neidermajer; B Schieffer; H Just; Detlev Ganten; H Drexler
Selective activation of cardiac angiotensinogen gene expression in post-infarction ventricular remodeling in the rat.
Journal of molecular and cellular cardiology 1993;25(2):133-43.
1993: Y McLaren; R Kreutz; Klaus Lindpaintner; D F Bohr; D Ganten; John L Reid; Anna F Dominiczak
Membrane microviscosity does not correlate with blood pressure: a cosegregation study.
Journal of hypertension 1993;11(1):25-30.
1993: Klaus Lindpaintner; P Hilbert; D Ganten; B Nadal-Ginard; T Inagami; N Iwai
Molecular genetics of the SA-gene: cosegregation with hypertension and mapping to rat chromosome 1.
Journal of hypertension 1993;11(1):19-23.
1992: Tadao Serikawa; Takashi Kuramoto; P Hilbert; M Mori; J Yamada; Christopher Dubay; Klaus Lindpaintner; D Ganten; J L Guénet; G M Lathrop
Rat gene mapping using PCR-analyzed microsatellites.
Genetics 1992;131(3):701-21.
1992: V J Dzau; H J Jacob; Klaus Lindpaintner; D Ganten; E S Lander
Genetic mapping in hypertension.
Journal of vascular surgery 1992;15(5):930.
1992: Klaus Lindpaintner; R Kreutz; D Ganten
Genetic variation in hypertensive and 'control' strains. What are we controlling for anyway?
Hypertension 1992;19(5):428-30.
1992: Diomedes E Logothetis; S Movahedi; C Satler; Klaus Lindpaintner; B Nadal-Ginard
Incremental reductions of positive charge within the S4 region of a voltage-gated K+ channel result in corresponding decreases in gating charge.
Neuron 1992;8(3):531-40.
1992: Klaus Lindpaintner
Genetic linkage analysis in hypertension: principles and practice.
Journal of hypertension 1992;10(2):121-4.
1992: Klaus Lindpaintner; N Niedermaier; H Drexler; D Ganten
Left ventricular remodeling after myocardial infarction: does the cardiac renin-angiotensin system play a role?
Journal of cardiovascular pharmacology 1992;20 Suppl 1():S41-7.
1991: Detlev Ganten; S Takahashi; Klaus Lindpaintner; J Mullins
Genetic basis of hypertension. The renin-angiotensin paradigm.
Hypertension 1991;18(5 Suppl):III109-14.
1991: P Hilbert; Klaus Lindpaintner; Jacques Beckmann; T Serikawa; F Soubrier; Christopher Dubay; P Cartwright; B De Gouyon; Cécile Julier; S Takahasi
Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats.
Nature 1991;353(6344):521-9.
1991: H J Jacob; Klaus Lindpaintner; S E Lincoln; K Kusumi; R K Bunker; Y P Mao; D Ganten; V J Dzau; Eric S Lander
Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat.
Cell 1991;67(1):213-24.
1991: Detlev Ganten; Klaus Lindpaintner; U Ganten; Jörg Peters; F Zimmermann; Michael Bader; J Mullins
Transgenic rats: new animal models in hypertension research. Invited lecture.
Hypertension 1991;17(6 Pt 2):843-55.
1991: Klaus Lindpaintner; Detlev Ganten
The cardiac renin-angiotensin system. An appraisal of present experimental and clinical evidence.
Circulation research 1991;68(4):905-21.
1990: Klaus Lindpaintner; M W Jin; N Niedermaier; M J Wilhelm; Detlev Ganten
Cardiac angiotensinogen and its local activation in the isolated perfused beating heart.
Circulation research 1990;67(3):564-73.
1990: Klaus Lindpaintner; S Takahashi; Detlev Ganten
Structural alterations of the renin gene in stroke-prone spontaneously hypertensive rats: examination of genotype-phenotype correlations.
Journal of hypertension 1990;8(8):763-73.
1989: Detlev Ganten; J Mullins; Klaus Lindpaintner
The tissue renin-angiotensin system: a target for angiotensin-converting enzyme inhibitors.
Journal of human hypertension 1989;3 Suppl 1():63-70.
1988: Klaus Lindpaintner; M Jin; M J Wilhelm; F Suzuki; Wolfgang Linz; B A Schoelkens; Detlev Ganten
Intracardiac generation of angiotensin and its physiologic role.
Circulation 1988;77(6 Pt 2):I18-23.
1988: M Jin; M J Wilhelm; R E Lang; Thomas Unger; Klaus Lindpaintner; Detlev Ganten
Endogenous tissue renin-angiotensin systems. From molecular biology to therapy.
The American journal of medicine 1988;84(3A):28-36.
1988: F Suzuki; G Ludwig; W Hellmann; Martin Paul; Klaus Lindpaintner; K Murakami; Detlev Ganten
Renin gene expression in rat tissues: a new quantitative assay method for rat renin mRNA using synthetic cRNA.
Clinical and experimental hypertension. Part A, Theory and practice 1988;10(2):345-59.
1988: F Suzuki; Klaus Lindpaintner; C Keuneke; W Hellmann; S Takahasi; Y Nakamura; H Ohkubo; S Nakanishi; K Murakami; Detlev Ganten
Tissue-specific regulation of gene expression for renin and angiotensinogen.
Clinical and experimental hypertension. Part A, Theory and practice 1988;10(6):1317-9.
1988: R Metzger; D Wagner; S Takahashi; F Suzuki; Klaus Lindpaintner; Detlev Ganten
Tissue renin-angiotensin systems aspects of molecular biology and pharmacology.
Clinical and experimental hypertension. Part A, Theory and practice 1988;10(6):1227-38.
1987: Klaus Lindpaintner; M J Wilhelm; M Jin; Thomas Unger; R E Lang; B A Schoelkens; Detlev Ganten
Tissue renin-angiotensin systems: focus on the heart.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1987;5(2):S33-8.