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Patricia Giardina
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Network (preview)
20
Grady, Robert
6
Kazazian, Haig
5
Boehm, Corinne
5
Vichinsky, Elliott
4
Rivella, Stefano
4
Neufeld, Ellis
4
Orkin, Stuart
4
Kwiatkowski, Janet
3
Coates, Thomas
3
Vogiatzi, Maria
3
Olivieri, Nancy
3
Migliaccio, Anna Rita
3
Rachmilewitz, Eliezer
3
Alberti, Daniele
3
Breda, Laura
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All Publications
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2008: Harmatz Paul; Jonas Maureen M; Kwiatkowski Janet L; Wright Elizabeth C; Fischer Roland; Vichinsky Elliott; Giardina Patricia J; Neufeld Ellis J; Porter John; Olivieri Nancy;
Safety and efficacy of pegylated interferon alpha-2a and ribavirin for the treatment of hepatitis C in patients with thalassemia.
Haematologica 2008;93(8):1247-51.
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2008: Libani Ilaria V; Guy Ella C; Melchiori Luca; Schiro Raffaella; Ramos Pedro; Breda Laura; Scholzen Thomas; Chadburn Amy; Liu YiFang; Kernbach Margrit; Baron-Lühr Bettina; Porotto Matteo; de Sousa Maria; Rachmilewitz Eliezer A; Hood John D; Cappellini M Domenica; Giardina Patricia J; Grady Robert W; Gerdes Johannes; Rivella Stefano
Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia.
Blood 2008;112(3):875-85.
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2008: Fung Ellen B; Harmatz Paul R; Milet Meredith; Coates Thomas D; Thompson Alexis A; Ranalli Mark; Mignaca Robert; Scher Charles; Giardina Patricia; Robertson Shanda; Neumayr Lynne; Vichinsky Elliott P;
Fracture prevalence and relationship to endocrinopathy in iron overloaded patients with sickle cell disease and thalassemia.
Bone 2008;43(1):162-8.
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2008: Walter Patrick B; Macklin Eric A; Porter John; Evans Patricia; Kwiatkowski Janet L; Neufeld Ellis J; Coates Thomas; Giardina Patricia J; Vichinsky Elliott; Olivieri Nancy; Alberti Daniele; Holland Jaymes; Harmatz Paul;
Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial.
Haematologica 2008;93(6):817-25.
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2008: Porter John; Galanello Renzo; Saglio Giuseppe; Neufeld Ellis J; Vichinsky Elliott; Cappellini Maria Domenica; Olivieri Nancy; Piga Antonio; Cunningham Melody J; Soulières Denis; Gattermann Norbert; Tchernia Gilbert; Maertens Johan; Giardina Patricia; Kwiatkowski Janet; Quarta Giovanni; Jeng Michael; Forni Gian Luca; Stadler Michael; Cario Holger; Debusscher Louisette; Della Porta Matteo; Cazzola Mario; Greenberg Peter; Alimena Giuliana; Rabault Bertrand; Gathmann Insa; Ford John Malcolm; Alberti Daniele; Rose Christian
Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): a 1-yr prospective study.
European journal of haematology 2008;80(2):168-76.
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2007: Harmatz Paul; Grady Robert W; Dragsten Paul; Vichinsky Elliott; Giardina Patricia; Madden Jacqueline; Jeng Michael; Miller Becky; Hanson Gregory; Hedlund Bo
Phase Ib clinical trial of starch-conjugated deferoxamine (40SD02): a novel long-acting iron chelator.
British journal of haematology 2007;138(3):374-81.
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2007: Gardenghi Sara; Marongiu Maria F; Ramos Pedro; Guy Ella; Breda Laura; Chadburn Amy; Liu YiFang; Amariglio Ninette; Rechavi Gideon; Rachmilewitz Eliezer A; Breuer William; Cabantchik Z Ioav; Wrighting Diedra M; Andrews Nancy C; de Sousa Maria; Giardina Patricia J; Grady Robert W; Rivella Stefano
Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.
Blood 2007;109(11):5027-35.
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2007: Sadelain Michel; Boulad Farid; Galanello Renzo; Giardina Patricia; Locatelli Franco; Maggio Aurelio; Rivella Stefano; Riviere Isabelle; Tisdale John
Therapeutic options for patients with severe beta-thalassemia: the need for globin gene therapy.
Human gene therapy 2007;18(1):1-9.
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2006: Cappellini Maria Domenica; Cohen Alan; Piga Antonio; Bejaoui Mohamed; Perrotta Silverio; Agaoglu Leyla; Aydinok Yesim; Kattamis Antonis; Kilinc Yurdanur; Porter John; Capra Marcello; Galanello Renzo; Fattoum Slaheddine; Drelichman Guillermo; Magnano Carmelo; Verissimo Monica; Athanassiou-Metaxa Miranda; Giardina Patricia; Kourakli-Symeonidis Alexandra; Janka-Schaub Gritta; Coates Thomas; Vermylen Christiane; Olivieri Nancy; Thuret Isabelle; Opitz Herbert; Ressayre-Djaffer Catherine; Marks Peter; Alberti Daniele
A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia.
Blood 2006;107(9):3455-62.
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2006: Vogiatzi M G; Macklin E A; Fung E B; Vichinsky E; Olivieri N; Kwiatkowski J; Cohen A; Neufeld E; Giardina P J
Prevalence of fractures among the Thalassemia syndromes in North America.
Bone 2006;38(4):571-5.
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2005: Vogiatzi Maria G; Autio Karen A; Mait Jeffrey E; Schneider Robert; Lesser Martin; Giardina Patricia J
Low bone mineral density in adolescents with beta-thalassemia.
Annals of the New York Academy of Sciences 2005;1054():462-6.
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2005: Breda Laura; Gardenghi Sara; Guy Ella; Rachmilewitz Eliezer A; Weizer-Stern Orly; Adamsky Konstantin; Amariglio Ninette; Rechavi Gideon; Giardina Patricia J; Grady Robert W; Rivella Stefano
Exploring the role of hepcidin, an antimicrobial and iron regulatory peptide, in increased iron absorption in beta-thalassemia.
Annals of the New York Academy of Sciences 2005;1054():417-22.
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2004: Vogiatzi Maria G; Autio Karen A; Schneider Robert; Giardina Patricia J
Low bone mass in prepubertal children with thalassemia major: insights into the pathogenesis of low bone mass in thalassemia.
Journal of pediatric endocrinology & metabolism : JPEM 2004;17(10):1415-21.
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2003: Nisbet-Brown Eric; Olivieri Nancy F; Giardina Patricia J; Grady Robert W; Neufeld Ellis J; Séchaud Romain; Krebs-Brown Axel J; Anderson Judith R; Alberti Daniele; Sizer Kurt C; Nathan David G
Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial.
Lancet 2003;361(9369):1597-602.
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2001: Giardina P J; Grady R W
Chelation therapy in beta-thalassemia: an optimistic update.
Seminars in hematology 2001;38(4):360-6.
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2001: Heath J A; Beaverson K; Giardina P; Boehm C; Cutting G
A novel beta-thalassemia intermedia phenotype containing Nt494+129T-->C and NT494+132C-->A mutations in cis and a Nt168C-->T (beta(o) 39 point) mutation in trans.
American journal of hematology 2001;67(1):57-8.
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2000: Cunningham-Rundles S; Giardina P J; Grady R W; Califano C; McKenzie P; De Sousa M
Effect of transfusional iron overload on immune response.
The Journal of infectious diseases 2000;182 Suppl 1():S115-21.
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1998: Grady R W; Giardina P J
Iron chelation with oral deferiprone in patients with thalassemia.
The New England journal of medicine 1998;339(23):1712-3; author reply 1713-4.
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1998: Boulad F; Giardina P; Gillio A; Kernan N; Small T; Brochstein J; Van Syckle K; George D; Szabolcs P; O'Reilly R J
Bone marrow transplantation for homozygous beta-thalassemia. The Memorial Sloan-Kettering Cancer Center experience.
Annals of the New York Academy of Sciences 1998;850():498-502.
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1998: Calleja E M; Shen J Y; Lesser M; Grady R W; New M I; Giardina P J
Survival and morbidity in transfusion-dependent thalassemic patients on subcutaneous desferrioxamine chelation. Nearly two decades of experience.
Annals of the New York Academy of Sciences 1998;850():469-70.
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1998: Bush S; Mandel F S; Giardina P J
Future orientation and life expectations of adolescents and young adults with thalassemia major.
Annals of the New York Academy of Sciences 1998;850():361-9.
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1998: Hayward A; Ambruso D; Battaglia F; Donlon T; Eddelman K; Giller R; Hobbins J; Hsia Y E; Quinones R; Shpall E; Trachtenberg E; Giardina P
Microchimerism and tolerance following intrauterine transplantation and transfusion for alpha-thalassemia-1.
Fetal diagnosis and therapy 1998;13(1):8-14.
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1997: Levine J E; Cohen A; MacQueen M; Martin M; Giardina P J
Sensorimotor neurotoxicity associated with high-dose deferoxamine treatment.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 1997;19(2):139-41.
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1997: Herbert V; Jayatilleke E; Shaw S; Rosman A S; Giardina P; Grady R W; Bowman B; Gunter E W
Serum ferritin iron, a new test, measures human body iron stores unconfounded by inflammation.
Stem cells (Dayton, Ohio) 1997;15(4):291-6.
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1996: Dumars K W; Boehm C; Eckman J R; Giardina P J; Lane P A; Shafer F E
Practical guide to the diagnosis of thalassemia. Council of Regional Networks for Genetic Services (CORN).
American journal of medical genetics 1996;62(1):29-37.
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1996: Pearson H A; Cohen A R; Giardina P J; Kazazian H H
The changing profile of homozygous beta-thalassemia: demography, ethnicity, and age distribution of current North American patients and changes in two decades.
Pediatrics 1996;97(3):352-6.
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1995: Giardina P J; Grady R W
Chelation therapy in beta-thalassemia: the benefits and limitations of desferrioxamine.
Seminars in hematology 1995;32(4):304-12.
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1995: Collins A F; Pearson H A; Giardina P; McDonagh K T; Brusilow S W; Dover G J
Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: a clinical trial.
Blood 1995;85(1):43-9.
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1994: Factor J M; Pottipati S R; Rappoport I; Rosner I K; Lesser M L; Giardina P J
Pulmonary function abnormalities in thalassemia major and the role of iron overload.
American journal of respiratory and critical care medicine 1994;149(6):1570-4.
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1994: Grady R W; Salbe A D; Hilgartner M W; Giardina P J
Results from a phase I clinical trial of HBED.
Advances in experimental medicine and biology 1994;356():351-9.
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1993: Koch D A; Giardina P J; Ryan M; MacQueen M; Hilgartner M W
Behavioral contracting to improve adherence in patients with thalassemia.
Journal of pediatric nursing 1993;8(2):106-11.
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1993: Galli M C; Giardina P J; Migliaccio A R; Migliaccio G
The biology of stem cell factor, a new hematopoietic growth factor involved in stem cell regulation.
International journal of clinical & laboratory research 1993;23(2):70-7.
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1992: Migliaccio G; Migliaccio A R; Druzin M L; Giardina P J; Zsebo K M; Adamson J W
Long-term generation of colony-forming cells in liquid culture of CD34+ cord blood cells in the presence of recombinant human stem cell factor.
Blood 1992;79(10):2620-7.
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1992: Giardina P J; Hilgartner M W
Update on thalassemia.
Pediatrics in review / American Academy of Pediatrics 1992;13(2):55-62.
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1992: Alter B P; He L; Acosta R; Knobloch M E; Thomson J C; Giardina P; Weinberg R S
Sickle and thalassemic erythroid progenitor cells are different from normal.
Hemoglobin 1992;16(6):447-67.
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1991: Watzke H H; Wallmark A; Hamaguchi N; Giardina P; Stafford D W; High K A
Factor XSanto Domingo. Evidence that the severe clinical phenotype arises from a mutation blocking secretion.
The Journal of clinical investigation 1991;88(5):1685-9.
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1991: Migliaccio G; Migliaccio A R; Druzin M L; Giardina P J; Zsebo K M; Adamson J W
Effects of recombinant human stem cell factor (SCF) on the growth of human progenitor cells in vitro.
Journal of cellular physiology 1991;148(3):503-9.
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1991: Ehlers K H; Giardina P J; Lesser M L; Engle M A; Hilgartner M W
Prolonged survival in patients with beta-thalassemia major treated with deferoxamine.
The Journal of pediatrics 1991;118(4 ( Pt 1)):540-5.
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1991: Brill P W; Winchester P; Giardina P J; Cunningham-Rundles S
Deferoxamine-induced bone dysplasia in patients with thalassemia major.
AJR. American journal of roentgenology 1991;156(3):561-5.
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1991: Kaufmann T; Coleman M; Giardina P; Nisce L Z
The role of radiation therapy in the management of hematopoietic neurologic complications in thalassemia.
Acta haematologica 1991;85(3):156-9.
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1990: Giardina P J; Grady R W; Ehlers K H; Burstein S; Graziano J H; Markenson A L; Hilgartner M W
Current therapy of Cooley's anemia. A decade of experience with subcutaneous desferrioxamine.
Annals of the New York Academy of Sciences 1990;612():275-85.
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1989: Wong C; Antonarakis S E; Goff S C; Orkin S H; Forget B G; Nathan D G; Giardina P J; Kazazian H H
Beta-thalassemia due to two novel nucleotide substitutions in consensus acceptor splice sequences of the beta-globin gene.
Blood 1989;73(4):914-8.
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1987: Akbar A N; Fitzgerald-Bocarsly P A; Giardina P J; Hilgartner M W; Grady R W
Modulation of the defective natural killer activity seen in thalassaemia major with desferrioxamine and alpha-interferon.
Clinical and experimental immunology 1987;70(2):345-53.
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1987: Robert-Guroff M; Giardina P J; Robey W G; Jennings A M; Naugle C J; Akbar A N; Grady R W; Hilgartner M W
HTLV-III neutralizing antibody development in transfusion-dependent seropositive patients with beta-thalassemia.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(11):3731-6.
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1987: Grady R W; Akbar A N; de Sousa M; Giardina P J; Hilgartner M W
Transfusion-related immunologic abnormalities in beta-thalassemia major.
Birth defects original article series 1987;23(5A):587-93.
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1986: Brochstein J A; Kirkpatrick D; Giardina P J; Weinberg R S; Alter B P; Driscoll C; Wolfe L; Shank B; O'Reilly R J
Bone marrow transplantation in two multiply transfused patients with thalassaemia major.
British journal of haematology 1986;63(3):445-56.
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1986: Boehm C D; Dowling C E; Waber P G; Giardina P J; Kazazian H H
Use of oligonucleotide hybridization in the characterization of a beta zero-thalassemia gene (beta 37 TGG----TGA) in a Saudi Arabian family.
Blood 1986;67(4):1185-8.
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1986: Akbar A N; Fitzgerald-Bocarsly P A; de Sousa M; Giardina P J; Hilgartner M W; Grady R W
Decreased natural killer activity in thalassemia major: a possible consequence of iron overload.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(5):1635-40.
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1985: Akbar A N; Giardina P J; Hilgartner M W; Grady R W
Immunological abnormalities in thalassaemia major. I. A transfusion-related increase in circulating cytoplasmic immunoglobulin-positive cells.
Clinical and experimental immunology 1985;62(2):397-404.
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1985: Grady R W; Akbar A N; Giardina P J; Hilgartner M W; de Sousa M
Disproportionate lymphoid cell subsets in thalassaemia major: the relative contributions of transfusion and splenectomy.
British journal of haematology 1985;59(4):713-24.
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1985: Engle M A; Ehlers K H; O'Loughlin J E; Giardina P J; Hilgartner M W
Beta thalassemia and heart disease: three decades of gradual progress.
Transactions of the American Clinical and Climatological Association 1985;96():24-33.
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1985: Sherman M; Koch D; Giardina P; Hymowitz P; Siegel R; Shapiro T
Thalassemic children's understanding of illness: a study of cognitive and emotional factors.
Annals of the New York Academy of Sciences 1985;445():327-36.
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1985: Woo R; Giardina P J; Hilgartner M W
A psychosocial needs assessment of patients with homozygous beta-thalassemia.
Annals of the New York Academy of Sciences 1985;445():316-23.
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1985: Giardina P J; Ehlers K H; Engle M A; Grady R W; Hilgartner M W
The effect of subcutaneous deferoxamine on the cardiac profile of thalassemia major: a five-year study.
Annals of the New York Academy of Sciences 1985;445():282-92.
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1984: Cheng T C; Orkin S H; Antonarakis S E; Potter M J; Sexton J P; Markham A F; Giardina P J; Li A; Kazazian H H
beta-Thalassemia in Chinese: use of in vivo RNA analysis and oligonucleotide hybridization in systematic characterization of molecular defects.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(9):2821-5.
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1983: Orkin S H; Sexton J P; Cheng T C; Goff S C; Giardina P J; Lee J I; Kazazian H H
ATA box transcription mutation in beta-thalassemia.
Nucleic acids research 1983;11(14):4727-34.
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1982: Grabowski E F; Giardina P J; Goldberg D; Masur H; Read S E; Hirsch R L; Benach J L
Babesiosis transmitted by a transfusion of frozen-thawed blood.
Annals of internal medicine 1982;96(4):466-7.
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1982: Orkin S H; Kazazian H H; Antonarakis S E; Goff S C; Boehm C D; Sexton J P; Waber P G; Giardina P J
Linkage of beta-thalassaemia mutations and beta-globin gene polymorphisms with DNA polymorphisms in human beta-globin gene cluster.
Nature 1982;296(5858):627-31.
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1982: Antonarakis S E; Boehm C D; Giardina P J; Kazazian H H
Nonrandom association of polymorphic restriction sites in the beta-globin gene cluster.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(1):137-41.
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1981: Graziano J H; Piomelli S; Hilgartner M; Giardina P; Karpatkin M; Andrew M; LoIacono N; Seaman C
Chelation therapy in beta-thalassemia major. III. The role of splenectomy in achieving iron balance.
The Journal of pediatrics 1981;99(5):695-9.
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1981: Burns A L; Spence S; Kosche K; Ramirez F; Mears J G; Schreiner H; Miller C; Baird M; Leibowitz D; Giardina P; Markenson A; Bank A
Isolation and characterization of cloned DNA: the delta and beta globin genes in homozygous beta + thalassemia.
Blood 1981;57(1):140-6.
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1979: Burstein Y; Giardina P J; Rausen A R; Kandall S R; Siljestrom K; Peterson C M
Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users.
The Journal of pediatrics 1979;94(6):895-9.
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