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Anne Astier

Research Profile

Chemicals & Drugs

Physiology

Anatomy

Phenomena

Phosphorylation

Disorders

Multiple Sclerosis

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Publications

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Karoline Kickler; Kathryn Maltby; Siobhán Ni Choileain; Jillian Stephen; Sheila Wright; David A Hafler; Henry N Jabbour; Anne L Astier
Prostaglandin E2 affects T cell responses through modulation of CD46 expression.
Siobhan Ni Choileain; Anne L Astier
CD46 processing: a means of expression.
Siobhan Ni Choileain; Anne L Astier
CD46 plasticity and its inflammatory bias in multiple sclerosis.

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All Publications

2012: Karoline Kickler; Kathryn Maltby; Siobhán Ni Choileain; Jillian Stephen; Sheila Wright; David A Hafler; Henry N Jabbour; Anne L Astier
Prostaglandin E2 affects T cell responses through modulation of CD46 expression.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(11):5303-10.
2012: Siobhan Ni Choileain; Anne L Astier
CD46 processing: a means of expression.
Immunobiology 2012;217(2):169-75.
2011: Siobhan Ni Choileain; Anne L Astier
CD46 plasticity and its inflammatory bias in multiple sclerosis.
Archivum immunologiae et therapiae experimentalis 2011;59(1):49-59.
2011: Siobhan Ni Choileain; Nathan J Weyand; Christian Neumann; Joelle Thomas; Magdalene So; Anne L Astier
The dynamic processing of CD46 intracellular domains provides a molecular rheostat for T cell activation.
PloS one 2011;6(1):e16287.
2010: Anne L Astier; Gaëlle Beriou; Thomas M Eisenhaure; Stephen M Anderton; David A Hafler; Nir Hacohen
RNA interference screen in primary human T cells reveals FLT3 as a modulator of IL-10 levels.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(2):685-93.
2008: Anne L Astier
T-cell regulation by CD46 and its relevance in multiple sclerosis.
Immunology 2008;124(2):149-54.
2008: Adi Vaknin-Dembinsky; Gopal Murugaiyan; David A Hafler; Anne L Astier; Howard L Weiner
Increased IL-23 secretion and altered chemokine production by dendritic cells upon CD46 activation in patients with multiple sclerosis.
Journal of neuroimmunology 2008;195(1-2):140-5.
2007: Anne L Astier; David A Hafler
Abnormal Tr1 differentiation in multiple sclerosis.
Journal of neuroimmunology 2007;191(1-2):70-8.
2006: Anne L Astier; Gregory Meiffren; Samuel Freeman; David A Hafler
Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis.
The Journal of clinical investigation 2006;116(12):3252-7.
2004: Olivier Munoz; F Fend; Rosalie de Beaumont; Hervé Husson; Anne L Astier; Arnold S Freedman
TGFbeta-mediated activation of Smad1 in B-cell non-Hodgkin's lymphoma and effect on cell proliferation.
Leukemia 2004;18(12):2015-25.
2004: Anne L Astier; Marek Svoboda; E Hinds; Rosalie de Beaumont; Olivier Munoz; Arnold S Freedman
Integrins regulate survival of pre-B-ALL cells through differential IAP and caspase-7 ubiquitination and degradation.
Leukemia 2004;18(4):873-5.
2003: Anne L Astier; Ronghui Xu; Marek Svoboda; Esther Hinds; Olivier Munoz; Rosalie de Beaumont; Colin Daniel Crean; Theodore G Gabig; Arnold S Freedman
Temporal gene expression profile of human precursor B leukemia cells induced by adhesion receptor: identification of pathways regulating B-cell survival.
Blood 2003;101(3):1118-27.
2002: Julien C Marie; Anne L Astier; Pierre Rivailler; Chantal Rabourdin-Combe; T Fabian Wild; Branka Horvat
Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation.
Nature immunology 2002;3(7):659-66.
2001: Y Zaffran; Olivier Destaing; A Roux; Stéphane Ory; T Nheu; Pierre Jurdic; Chantal Rabourdin-Combe; Anne L Astier
CD46/CD3 costimulation induces morphological changes of human T cells and activation of Vav, Rac, and extracellular signal-regulated kinase mitogen-activated protein kinase.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(12):6780-5.
2000: Anne L Astier; Marie-Claude Trescol-Biémont; Olga Azocar; B Lamouille; Chantal Rabourdin-Combe
Cutting edge: CD46, a new costimulatory molecule for T cells, that induces p120CBL and LAT phosphorylation.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(12):6091-5.
2000: Pierre-Olivier Vidalain; Olga Azocar; B Lamouille; Anne L Astier; Chantal Rabourdin-Combe; Christine Servet-Delprat
Measles virus induces functional TRAIL production by human dendritic cells.
Journal of virology 2000;74(1):556-9.
1997: Anne L Astier; SN Manié; SF Law; Timothy Canty; N Haghayghi; Brian J Druker; Ravi Salgia; Erica A Golemis; Arnold S Freedman
Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cells.
Leukemia & lymphoma 1997;28(1-2):65-72.
1997: Anne L Astier; SN Manié; Hava Karsenty Avraham; H Hirai; SF Law; Ye Zhang; Erica A Golemis; Y Fu; Brian J Druker; N Haghayeghi; Arnold S Freedman; Shalom Avraham
The related adhesion focal tyrosine kinase differentially phosphorylates p130Cas and the Cas-like protein, p105HEF1.
The Journal of biological chemistry 1997;272(32):19719-24.
1997: Anne L Astier; H Merle-Beral; Henri de la Salle; Janine Moncuit; Jean-Pierre Cazenave; Wolf H Fridman; Daniel Hanau; Jean-Luc Teillaud
Soluble Fcgamma receptor, Fc gammaRIIa2, is present in two forms in human serum and is increased in patients: with stage C chronic lymphocytic leukemia.
Leukemia & lymphoma 1997;26(3-4):317-26.
1997: SN Manié; Anne L Astier; N Haghayeghi; Timothy Canty; Brian J Druker; H Hirai; Arnold S Freedman
Regulation of integrin-mediated p130(Cas) tyrosine phosphorylation in human B cells. A role for p59(Fyn) and SHP2.
The Journal of biological chemistry 1997;272(25):15636-41.
1997: SN Manié; A R Beck; Anne L Astier; SF Law; Timothy Canty; H Hirai; Brian J Druker; Hava Karsenty Avraham; N Haghayeghi; Martin Sattler; Ravi Salgia; James D Griffin; Erica A Golemis; Arnold S Freedman
Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells.
The Journal of biological chemistry 1997;272(7):4230-6.
1997: Anne L Astier; Hava Karsenty Avraham; S N Manie; John Groopman; Timothy Canty; Shalom Avraham; Arnold S Freedman
The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after beta1-integrin stimulation in B cells and binds to p130cas.
The Journal of biological chemistry 1997;272(1):228-32.
1997: Henri de la Salle; H Haegel-Kronenberger; Huguette Bausinger; Anne L Astier; Jean-Pierre Cazenave; Wolf H Fridman; C Sautès; Jean-Luc Teillaud; Daniel Hanau; Thomas Bieber
Functions of Fc receptors on human dendritic Langerhans cells.
International reviews of immunology 1997;16(1-2):187-203.
1997: SN Manié; Martin Sattler; Anne L Astier; J S Phifer; Timothy Canty; Chikao Morimoto; Brian J Druker; Ravi Salgia; James D Griffin; Arnold S Freedman
Tyrosine phosphorylation of the product of the c-cbl protooncogene is [corrected] induced after integrin stimulation.
Experimental hematology 1997;25(1):45-50.
1996: S N Manie; Anne L Astier; D Wang; J S Phifer; J Chen; A I Lazarovits; Chikao Morimoto; Arnold S Freedman
Stimulation of tyrosine phosphorylation after ligation of beta7 and beta1 integrins on human B cells.
Blood 1996;87(5):1855-61.
1995: Christian Gachet; Anne L Astier; Henri de la Salle; C de la Salle; Wolf H Fridman; Jean-Pierre Cazenave; Daniel Hanau; Jean-Luc Teillaud
Release of Fc gamma RIIa2 by activated platelets and inhibition of anti-CD9-mediated platelet aggregation by recombinant Fc gamma RIIa2.
Blood 1995;85(3):698-704.
1994: Jean-Luc Teillaud; C Bouchard; Anne L Astier; C Teillaud; Eric Tartour; Jean Michon; Annie Galinha; Janine Moncuit; N Mazières; R Spagnoli
Natural and recombinant soluble low-affinity Fc gamma R: detection, purification, and functional activities.
ImmunoMethods 1994;4(1):48-64.
1994: Anne L Astier; Henri de la Salle; C de la Salle; Thomas Bieber; Marie-Emmanuelle BEHR-GROSS; M Freund; Jean-Pierre Cazenave; Wolf H Fridman; Jean-Luc Teillaud; Daniel Hanau
Human epidermal Langerhans cells secrete a soluble receptor for IgG (Fc gamma RII/CD32) that inhibits the binding of immune complexes to Fc gamma R+ cells.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(1):201-12.
1993: Anne L Astier; Henri de la Salle; Janine Moncuit; M Freund; Jean-Pierre Cazenave; Wolf H Fridman; Daniel Hanau; Jean-Luc Teillaud
Detection and quantification of secreted soluble Fc gamma RIIA in human sera by an enzyme-linked immunosorbent assay.
Journal of immunological methods 1993;166(1):1-10.
1993: Wolf H Fridman; Jean-Luc Teillaud; C Bouchard; C Teillaud; Anne L Astier; Eric Tartour; Jérôme Galon; Claire Mathiot; C Sautès
Soluble Fc gamma receptors.
Journal of leukocyte biology 1993;54(5):504-12.
1992: J Cartron; J L Celton; Pierre Gane; Anne L Astier; W H Fridman; G Boissinot; J P Cartron
Iso-immune neonatal neutropenia due to an anti-Fc receptor III (CD16) antibody.
European journal of pediatrics 1992;151(6):438-41.
1990: Jean-Luc Teillaud; S Brunati; M Elmalek; Anne L Astier; P Nicaise; Janine Moncuit; Claire Mathiot; C Job-Deslandre; Wolf H Fridman
Involvement of FcR+ T cells and of IgG-BF in the control of myeloma cells.
Molecular immunology 1990;27(12):1209-17.