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Corrado Busi

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Anatomy

Liver

Living Beings

Disorders

Concepts & Ideas

Tissue Distribution

Physiology

Virus Replication

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Co-Publications
Name
49
Fiume, Luigi
34
Mattioli, Alessandro
28
Di Stefano, Giuseppina
6
Chieco, Pasquale
6
Bonino, Ferruccio
5
Kratz, Felix
4
Pariali, Milena
4
Verme, G
4
Rapicetta, Maria
4
Torrani-Cerenzia, MR
4
Derenzini, Massimo
4
Baglioni, Michele
3
Balboni, Pier Giorgio
3
Bolondi, Luigi
3
Brunetto, Maurizia Rossana

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Publications

TOP 3
Fiume L; Baglioni M; Busi C; Manerba M; Di Stefano G
The enhancement of interstitial transport of a doxorubicin-lactosaminated albumin conjugate by imatinib: in rat hepatocellular carcinoma it is not preferentially higher than that in liver and bone marrow.
Di Stefano Giuseppina; Fiume Luigi; Baglioni Michele; Busi Corrado; Bolondi Luigi; Farina Claudio; Mori Filippo; Chieco Pasquale; Pariali Milena; Kratz Felix; Molin Laura; Salmaso Stefano; Caliceti Paolo
Doxorubicin coupled to lactosaminated albumin: effect of heterogeneity in drug load on conjugate disposition and hepatocellular carcinoma uptake in rats.
Di Stefano Giuseppina; Fiume Luigi; Baglioni Michele; Busi Corrado; Chieco Pasquale; Kratz Felix; Mattioli Alessandro
Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin.

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All Publications

2009: Fiume L; Baglioni M; Busi C; Manerba M; Di Stefano G
The enhancement of interstitial transport of a doxorubicin-lactosaminated albumin conjugate by imatinib: in rat hepatocellular carcinoma it is not preferentially higher than that in liver and bone marrow.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2009;72(3):630-1.
2008: Di Stefano Giuseppina; Fiume Luigi; Baglioni Michele; Busi Corrado; Bolondi Luigi; Farina Claudio; Mori Filippo; Chieco Pasquale; Pariali Milena; Kratz Felix; Molin Laura; Salmaso Stefano; Caliceti Paolo
Doxorubicin coupled to lactosaminated albumin: effect of heterogeneity in drug load on conjugate disposition and hepatocellular carcinoma uptake in rats.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;33(2):191-8.
2007: Di Stefano Giuseppina; Fiume Luigi; Baglioni Michele; Busi Corrado; Chieco Pasquale; Kratz Felix; Mattioli Alessandro
Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;30(2):136-42.
2006: Di Stefano Giuseppina; Fiume Luigi; Baglioni Michele; Bolondi Luigi; Busi Corrado; Chieco Pasquale; Kratz Felix; Manaresi Francesca; Pariali Milena
A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentiation grade.
Liver international : official journal of the International Association for the Study of the Liver 2006;26(6):726-33.
2006: Di Stefano G; Fiume L; Domenicali M; Busi C; Chieco P; Kratz F; Lanza M; Mattioli A; Pariali M; Bernardi M
Doxorubicin coupled to lactosaminated albumin: Effects on rats with liver fibrosis and cirrhosis.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2006;38(6):404-8.
2006: Di Stefano G; Busi C; Fiume L; Chieco P; Pariali M
Doxorubicin coupled to lactosaminated albumin: enhanced drug levels in rat hepatocarcinomas.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2006;38(4):284-5.
2005: Fiume Luigi; Bolondi Luigi; Busi Corrado; Chieco Pasquale; Kratz Felix; Lanza Marcella; Mattioli Alessandro; Di Stefano Giuseppina
Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine.
Journal of hepatology 2005;43(4):645-52.
2002: Di Stefano G; Busi C; Fiume L
Floxuridine coupling with lactosaminated human albumin to increase drug efficacy on liver micrometastases.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2002;34(6):439-46.
2002: Di Stefano Giuseppina; Lanza Marcella; Busi Corrado; Barbieri Luigi; Fiume Luigi
Conjugates of nucleoside analogs with lactosaminated human albumin to selectively increase the drug levels in liver blood: requirements for a regional chemotherapy.
The Journal of pharmacology and experimental therapeutics 2002;301(2):638-42.
2001: Di Stefano G; Busi C; Camerino A; Derenzini M; Trerè D; Fiume L
Coupling of 5-fluoro 2'-deoxyuridine to lactosaminated poly-l-lysine: an approach to a regional, non-invasive chemotherapy of liver micrometastases.
Biochemical pharmacology 2001;61(4):459-65.
2000: Di Stefano G; Busi C; Camerino A; Nardo B; Fiume L
Enhanced liver blood concentrations of adenine arabinoside accomplished by lactosaminated poly-L-lysine coupling: implications for regional chemotherapy of hepatic micrometastases.
Biochemical pharmacology 2000;59(3):301-4.
1999: Di Stefano G; Busi C; Mattioli A; Derenzini M; Trerè D; Fiume L
Inhibition of [3H]thymidine incorporation into DNA of rat regenerating liver by 2',2'-difluorodeoxycytidine coupled to lactosaminated poly-L-lysine.
Biochemical pharmacology 1999;57(7):793-9.
1998: Fiume L; Di Stefano G; Busi C; Incitti F; Rapicetta M; Farina C; Gervasi G B; Bonino F
Coupling to lactosaminated poly-L-lysine reduces the toxic effects of ribavirin on red blood cells.
Journal of hepatology 1998;29(6):1032-3.
1998: Di Stefano G; Busi C; Derenzini M; Trerè D; Fiume L
Conjugation of 5-fluoro-2'-deoxyuridine with lactosaminated poly-l-lysine to reduce extrahepatic toxicity in the treatment of hepatocarcinomas.
Italian journal of gastroenterology and hepatology 1998;30(2):173-7.
1997: Di Stefano G; Bignamini A; Busi C; Colonna F P; Fiume L
Enhanced accumulation of ribavirin and its metabolites in liver versus erythrocytes in mice administered with the liver targeted drug.
Italian journal of gastroenterology and hepatology 1997;29(5):420-6.
1997: Di Stefano G; Colonna F P; Bongini A; Busi C; Mattioli A; Fiume L
Ribavirin conjugated with lactosaminated poly-L-lysine: selective delivery to the liver and increased antiviral activity in mice with viral hepatitis.
Biochemical pharmacology 1997;54(3):357-63.
1997: Fiume L; Di Stefano G; Busi C; Mattioli A; Battista Gervasi G; Bertini M; Bartoli C; Catalani R; Caccia G; Farina C; Fissi A; Pieroni O; Giuseppetti R; D'Ugo E; Bruni R; Rapicetta M
Hepatotropic conjugate of adenine arabinoside monophosphate with lactosaminated poly-L-lysine. Synthesis of the carrier and pharmacological properties of the conjugate.
Journal of hepatology 1997;26(2):253-9.
1997: Fiume L; Di Stefano G; Busi C; Mattioli A; Bonino F; Torrani-Cerenzia M; Verme G; Rapicetta M; Bertini M; Gervasi G B
Liver targeting of antiviral nucleoside analogues through the asialoglycoprotein receptor.
Journal of viral hepatitis 1997;4(6):363-70.
1996: Torrani Cerenzia M; Fiume L; De Bernardi Venon W; Lavezzo B; Brunetto M R; Ponzetto A; Di Stefano G; Busi C; Mattioli A; Gervasi G B; Bonino F; Verme G
Adenine arabinoside monophosphate coupled to lactosaminated human albumin administered for 4 weeks in patients with chronic type B hepatitis decreased viremia without producing significant side effects.
Hepatology (Baltimore, Md.) 1996;23(4):657-61.
1995: Fiume L; Di Stefano G; Busi C; Mattioli A; Rapicetta M; Giuseppetti R; Ciccaglione A R; Argentini C
Inhibition of woodchuck hepatitis virus replication by adenine arabinoside monophosphate coupled to lactosaminated poly-L-lysine and administered by intramuscular route.
Hepatology (Baltimore, Md.) 1995;22(4 Pt 1):1072-7.
1995: Di Stefano G; Busi C; Mattioli A; Fiume L
Selective delivery to the liver of antiviral nucleoside analogs coupled to a high molecular mass lactosaminated poly-L-lysine and administered to mice by intramuscular route.
Biochemical pharmacology 1995;49(12):1769-75.
1995: Fiume L; Busi C; Di Stefano G; Mattioli A; Torrani-Cerenzia M; Bonino F; Capra G; De Bernardi W; Ponzetto A; Lavezzo B
Liver targeting of adenine arabinoside monophosphate (ara-AMP) by coupling to lactosaminated human serum albumin.
The Italian journal of gastroenterology 1995;27(4):189-92.
1994: Fiume L; Busi C; Corzani S; Di Stefano G; Gervasi G B; Mattioli A
Organ distribution of a conjugate of adenine arabinoside monophosphate with lactosaminated albumin in the rat.
Journal of hepatology 1994;20(5):681-2.
1994: Torrani Cerenzia M R; Fiume L; Busi C; Mattioli A; Di Stefano G; Gervasi G B; Brunetto M R; Piantino P; Verme G; Bonino F
Inhibition of hepatitis B virus replication by adenine arabinoside monophosphate coupled to lactosaminated albumin. Efficacy and minimal active dose.
Journal of hepatology 1994;20(2):307-9.
1994: Fiume L; Di Stefano G; Busi C; Mattioli A
A conjugate of lactosaminated poly-L-lysine with adenine arabinoside monophosphate, administered to mice by intramuscular route, accomplishes a selective delivery of the drug to the liver.
Biochemical pharmacology 1994;47(4):643-50.
1993: Fiume L; Busi C; Di Stefano G; Mattioli A
Coupling of antiviral nucleoside analogs to lactosaminated human albumin by using the imidazolides of their phosphoric esters.
Analytical biochemistry 1993;212(2):407-11.
1992: Fiume L; Betts C M; Busi C; Corzani S; Derenzini M; Di Stefano G; Mattioli A
The pathogenesis of vacuoles produced in rat and mouse liver cells by a conjugate of adenine arabinoside monophosphate with lactosaminated albumin.
Journal of hepatology 1992;15(3):314-22.
1991: Ponzetto A; Fiume L; Forzani B; Song S Y; Busi C; Mattioli A; Spinelli C; Marinelli M; Smedile A; Chiaberge E
Adenine arabinoside monophosphate and acyclovir monophosphate coupled to lactosaminated albumin reduce woodchuck hepatitis virus viremia at doses lower than do the unconjugated drugs.
Hepatology (Baltimore, Md.) 1991;14(1):16-24.
1991: Fiume L; Mattioli A; Busi C; Corzani S; Di Stefano G
High-pressure liquid chromatographic method for determining adenine arabinoside monophosphate coupled to lactosaminated albumin in plasma.
Pharmaceutica acta Helvetiae 1991;66(8):230-2.
1989: Fiume L; Busi C; Mattioli A; Spinelli C; Spinosa G; Bongini A
A conjugate of acyclovir monophosphate with lactosaminated albumin releases the phosphorylated drug in liver cells.
Die Naturwissenschaften 1989;76(2):74-6.
1989: Fiume L; Chiricolo M; Busi C; Mattioli A; Spinelli C; Spinosa G; Bartolini G; Minghetti L; Orlandi M; Tomasi V
A conjugate of prednisolone with albumin is pharmacologically active in macrophages.
Pharmaceutica acta Helvetiae 1989;64(12):351-2.
1988: Fiume L; Cerenzia M R; Bonino F; Busi C; Mattioli A; Brunetto M R; Chiaberge E; Verme G
Inhibition of hepatitis B virus replication by vidarabine monophosphate conjugated with lactosaminated serum albumin.
Lancet 1988;2(8601):13-5.
1988: Fiume L; Busi C; Mattioli A; Spinosa G
Targeting of antiviral drugs bound to protein carriers.
Critical reviews in therapeutic drug carrier systems 1988;4(4):265-84.
1987: Fiume L; Busi C; Mattioli A; Spinosa G
Increased immunogenicity of some native antigenic determinants in a chemically changed human albumin.
Die Naturwissenschaften 1987;74(12):595-6.
1987: Fiume L; Busi C; Preti P; Spinosa G
Conjugates of ara-AMP with lactosaminated albumin: a study on their immunogenicity in mouse and rat.
Cancer drug delivery 1987;4(3):145-50.
1986: Fiume L; Bassi B; Busi C; Mattioli A; Spinosa G; Faulstich H
Galactosylated poly(L-lysine) as a hepatotropic carrier of 9-beta-D-arabinofuranosyladenine 5'-monophosphate.
FEBS letters 1986;203(2):203-6.
1986: Fiume L; Bassi B; Busi C; Mattioli A; Spinosa G
Drug targeting in antiviral chemotherapy. A chemically stable conjugate of 9-beta-D-arabinofuranosyl-adenine 5'-monophosphate with lactosaminated albumin accomplishes a selective delivery of the drug to liver cells.
Biochemical pharmacology 1986;35(6):967-72.
1986: Fiume L; Balboni P G; Bassi B; Busi C; Mattioli A; Spinosa G
9-beta-D-arabinofuranosyl-adenine 5' monophosphate coupled to lactosaminated albumin is not metabolized in mouse bloodstream.
Pharmaceutica acta Helvetiae 1986;61(12):342-4.
1985: Fiume L; Bassi B; Busi C; Mattioli A; Wieland T
A study on the pharmacokinetics in mouse of adenine-9-beta-D-arabinofuranoside 5-monophosphate conjugated with lactosaminated albumin.
Experientia 1985;41(10):1326-8.
1985: Vesconi S; Langer M; Iapichino G; Costantino D; Busi C; Fiume L
Therapy of cytotoxic mushroom intoxication.
Critical care medicine 1985;13(5):402-6.
1985: Fiume L; Bassi B; Busi C; Mattioli A
Preparation of a lactosaminated albumin-ara-AMP conjugate which remains soluble after lyophilization.
Pharmaceutica acta Helvetiae 1985;60(11):318-20.
1984: Fiume L; Mattioli A; Busi C; Accorsi C
Selective penetration and pharmacological activity of lactosaminated albumin conjugates of adenine arabinoside 5-monophosphate (ara-AMP) in mouse liver.
Gut 1984;25(12):1392-8.
1983: Fiume L; Busi C; Mattioli A
Targeting of antiviral drugs by coupling with protein carriers.
FEBS letters 1983;153(1):6-10.
1982: Fiume L; Busi C; Mattioli A
Lactosaminated human serum albumin as hepatotropic drug carrier. Rate of uptake by mouse liver.
FEBS letters 1982;146(1):42-6.
1982: Fiume L; Mattioli A; Busi C; Spinosa G; Wieland T
Conjugates of adenine 9-alpha-D-arabinofuranoside monophosphate (ara-AMP) with lactosaminated homologous albumin are not immunogenic in the mouse.
Experientia 1982;38(9):1087-9.
1981: Fiume L; Busi C; Mattioli A; Balboni P G; Barbanti-Brodano G
Hepatocyte targeting of adenine-9-beta-D-arabinofuranoside 5' -monophosphate (ara-AMP) coupled to lactosaminated albumin.
FEBS letters 1981;129(2):261-4.
1981: Campadelli-Fiume G; Scannavini M; Falasca A; Hakim G; Busi C; Mattioli A; Fiume L
Reduction of simian virus 40 growth by a mitotic inhibitor extracted from liver. Evidence that the inhibitor is arginase.
Annali Sclavo; rivista di microbiologia e di immunologia 1981;23(2):162-8.
1981: Campadelli-Fiume G; Sinibaldi P; Busi C; Mattioli A; Fiume L
Inhibition of simian virus 40 growth in a kidney cell line by an endogenous inhibitor of renal cell proliferation.
Annali Sclavo; rivista di microbiologia e di immunologia 1981;23(1):52-6.
1980: Fiume L; Mattioli A; Busi C; Balboni P G; Barbanti-Brodano G; De Vries J; Altmann R; Wieland T
Selective inhibition of Ectromelia virus DNA synthesis in hepatocytes by adenine-9-beta-D-arabinofuranoside (ara-A) and adenine-9-beta-D-arabinofuranoside 5'-monophosphate (ara-AMP) conjugated to asialofetuin.
FEBS letters 1980;116(2):185-8.

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