Peter Young

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Pan Zhengying; Scheerens Heleen; Li Shyr-Jiann; Schultz Brian E; Sprengeler Paul A; Burrill L Chuck; Mendonca Rohan V; Sweeney Michael D; Scott Keana C K; Grothaus Paul G; Jeffery Douglas A; Spoerke Jill M; Honigberg Lee A; Young Peter R; Dalrymple Stacie A; Palmer James T
Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase.
Spencer Jeffrey R; Sendzik Martin; Oeh Jason; Sabbatini Peter; Dalrymple Stacie A; Magill Catherine; Kim Hyunjin M; Zhang Penglie; Squires Neil; Moss Katherine G; Sukbuntherng Juthamas; Graupe Doris; Eksterowicz John; Young Peter R; Myers Andrew G; Green Michael J
Evaluation of antitumor properties of novel saframycin analogs in vitro and in vivo.
Buggy Joseph J; Cao Z Alexander; Bass Kathryn E; Verner Erik; Balasubramanian Sriram; Liu Liang; Schultz Brian E; Young Peter R; Dalrymple Stacie A
CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo.

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2007: Pan Zhengying; Scheerens Heleen; Li Shyr-Jiann; Schultz Brian E; Sprengeler Paul A; Burrill L Chuck; Mendonca Rohan V; Sweeney Michael D; Scott Keana C K; Grothaus Paul G; Jeffery Douglas A; Spoerke Jill M; Honigberg Lee A; Young Peter R; Dalrymple Stacie A; Palmer James T
Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase.
ChemMedChem 2007;2(1):58-61.
2006: Spencer Jeffrey R; Sendzik Martin; Oeh Jason; Sabbatini Peter; Dalrymple Stacie A; Magill Catherine; Kim Hyunjin M; Zhang Penglie; Squires Neil; Moss Katherine G; Sukbuntherng Juthamas; Graupe Doris; Eksterowicz John; Young Peter R; Myers Andrew G; Green Michael J
Evaluation of antitumor properties of novel saframycin analogs in vitro and in vivo.
Bioorganic & medicinal chemistry letters 2006;16(18):4884-8.
2006: Buggy Joseph J; Cao Z Alexander; Bass Kathryn E; Verner Erik; Balasubramanian Sriram; Liu Liang; Schultz Brian E; Young Peter R; Dalrymple Stacie A
CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo.
Molecular cancer therapeutics 2006;5(5):1309-17.
2003: Liu Phillip C C; Huber Reid; Stow Mark D; Schlingmann Karen L; Collier Paul; Liao Boshan; Link John; Burn Tim C; Hollis Greg; Young Peter R; Mukherjee Ranjan
Induction of endogenous genes by peroxisome proliferator activated receptor alpha ligands in a human kidney cell line and in vivo.
The Journal of steroid biochemistry and molecular biology 2003;85(1):71-9.
2003: Doyle Michael L; Tian Shin-Shay; Miller Stephen G; Kessler Linda; Baker Audrey E; Brigham-Burke Michael R; Dillon Susan B; Duffy Kevin J; Keenan Richard M; Lehr Ruth; Rosen Jon; Schneeweis Lumelle A; Trill John; Young Peter R; Luengo Juan I; Lamb Peter
Selective binding and oligomerization of the murine granulocyte colony-stimulating factor receptor by a low molecular weight, nonpeptidyl ligand.
The Journal of biological chemistry 2003;278(11):9426-34.
2003: Kassam Altaf; Miao Bowman; Young Peter R; Mukherjee Ranjan
Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding.
The Journal of biological chemistry 2003;278(12):10028-32.
2002: Wang Xinkang; Xu Lin; Wang Hugh; Young Peter R; Gaestel Matthias; Feuerstein Giora Z
Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice.
The Journal of biological chemistry 2002;277(46):43968-72.
2002: Zhu Yuan; Xu Gang; Patel Arun; McLaughlin Megan M; Silverman Carol; Knecht Kristin; Sweitzer Sharon; Li Xiaotong; McDonnell Peter; Mirabile Rosanna; Zimmerman Dawn; Boyce Rogely; Tierney Lauren A; Hu Erding; Livi George P; Wolf Bryan; Abdel-Meguid Sherin S; Rose George D; Aurora Rejeev; Hensley Preston; Briggs Michael; Young Peter R
Cloning, expression, and initial characterization of a novel cytokine-like gene family.
Genomics 2002;80(2):144-50.
2002: Mukherjee Ranjan; Sun Shaoxian; Santomenna Linda; Miao Bowman; Walton Harry; Liao Boshan; Locke Kenneth; Zhang Ji-Hu; Nguyen Sonny H; Zhang Li Tao; Murphy Kathleen; Ross Harold O; Xia M X; Teleha Christopher; Chen S-Y; Selling Bernard; Wynn Richard; Burn Timothy; Young Peter R
Ligand and coactivator recruitment preferences of peroxisome proliferator activated receptor alpha.
The Journal of steroid biochemistry and molecular biology 2002;81(3):217-25.
2002: Huber Reid M; Murphy Kathleen; Miao Bowman; Link John R; Cunningham Mark R; Rupar Mark J; Gunyuzlu Paul L; Haws Thomas F; Kassam Altaf; Powell Francoise; Hollis Gregory F; Young Peter R; Mukherjee Ranjan; Burn Timothy C
Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters.
Gene 2002;290(1-2):35-43.
2001: Cheng D; Meegalla R L; He B; Cromley D A; Billheimer J T; Young P R
Human acyl-CoA:diacylglycerol acyltransferase is a tetrameric protein.
The Biochemical journal 2001;359(Pt 3):707-14.
2001: Sims J E; Nicklin M J; Bazan J F; Barton J L; Busfield S J; Ford J E; Kastelein R A; Kumar S; Lin H; Mulero J J; Pan J; Pan Y; Smith D E; Young P R
A new nomenclature for IL-1-family genes.
Trends in immunology 2001;22(10):536-7.
2000: Ozaki K; Kikly K; Michalovich D; Young P R; Leonard W J
Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(21):11439-44.
2000: Uddin S; Lekmine F; Sharma N; Majchrzak B; Mayer I; Young P R; Bokoch G M; Fish E N; Platanias L C
The Rac1/p38 mitogen-activated protein kinase pathway is required for interferon alpha-dependent transcriptional activation but not serine phosphorylation of Stat proteins.
The Journal of biological chemistry 2000;275(36):27634-40.
2000: Kumar S; McDonnell P C; Lehr R; Tierney L; Tzimas M N; Griswold D E; Capper E A; Tal-Singer R; Wells G I; Doyle M L; Young P R
Identification and initial characterization of four novel members of the interleukin-1 family.
The Journal of biological chemistry 2000;275(14):10308-14.
2000: Feuerstein G Z; Young P R
Apoptosis in cardiac diseases: stress- and mitogen-activated signaling pathways.
Cardiovascular research 2000;45(3):560-9.
2000: Hensley P; Doyle M L; Myszka D G; Woody R W; Brigham-Burke M R; Erickson-Miller C L; Griffin C A; Jones C S; McNulty D E; O'Brien S P; Amegadzie B Y; MacKenzie L; Ryan M D; Young P R
Evaluating energetics of erythropoietin ligand binding to homodimerized receptor extracellular domains.
Methods in enzymology 2000;323():177-207.
1999: Gum R J; Young P R
Identification of two distinct regions of p38 MAPK required for substrate binding and phosphorylation.
Biochemical and biophysical research communications 1999;266(1):284-9.
1999: Uddin S; Majchrzak B; Woodson J; Arunkumar P; Alsayed Y; Pine R; Young P R; Fish E N; Platanias L C
Activation of the p38 mitogen-activated protein kinase by type I interferons.
The Journal of biological chemistry 1999;274(42):30127-31.
1999: Scheid M P; Foltz I N; Young P R; Schrader J W; Duronio V
Ceramide and cyclic adenosine monophosphate (cAMP) induce cAMP response element binding protein phosphorylation via distinct signaling pathways while having opposite effects on myeloid cell survival.
Blood 1999;93(1):217-25.
1998: Marshall L A; Hansbury M J; Bolognese B J; Gum R J; Young P R; Mayer R J
Inhibitors of the p38 mitogen-activated kinase modulate IL-4 induction of low affinity IgE receptor (CD23) in human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(11):6005-13.
1998: Harrop J A; McDonnell P C; Brigham-Burke M; Lyn S D; Minton J; Tan K B; Dede K; Spampanato J; Silverman C; Hensley P; DiPrinzio R; Emery J G; Deen K; Eichman C; Chabot-Fletcher M; Truneh A; Young P R
Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth.
The Journal of biological chemistry 1998;273(42):27548-56.
1998: Young P R
Pharmacological modulation of cytokine action and production through signaling pathways.
Cytokine & growth factor reviews 1998;9(3-4):239-57.
1998: Wang Z; Canagarajah B J; Boehm J C; Kassisà S; Cobb M H; Young P R; Abdel-Meguid S; Adams J L; Goldsmith E J
Structural basis of inhibitor selectivity in MAP kinases.
Structure (London, England : 1993) 1998;6(9):1117-28.
1998: Harrop J A; Reddy M; Dede K; Brigham-Burke M; Lyn S; Tan K B; Silverman C; Eichman C; DiPrinzio R; Spampanato J; Porter T; Holmes S; Young P R; Truneh A
Antibodies to TR2 (herpesvirus entry mediator), a new member of the TNF receptor superfamily, block T cell proliferation, expression of activation markers, and production of cytokines.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1786-94.
1998: Gum R J; McLaughlin M M; Kumar S; Wang Z; Bower M J; Lee J C; Adams J L; Livi G P; Goldsmith E J; Young P R
Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket.
The Journal of biological chemistry 1998;273(25):15605-10.
1998: Emery J G; McDonnell P; Burke M B; Deen K C; Lyn S; Silverman C; Dul E; Appelbaum E R; Eichman C; DiPrinzio R; Dodds R A; James I E; Rosenberg M; Lee J C; Young P R
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.
The Journal of biological chemistry 1998;273(23):14363-7.
1998: White J R; Lee J M; Young P R; Hertzberg R P; Jurewicz A J; Chaikin M A; Widdowson K; Foley J J; Martin L D; Griswold D E; Sarau H M
Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration.
The Journal of biological chemistry 1998;273(17):10095-8.
1997: Salmon R A; Foltz I N; Young P R; Schrader J W
The p38 mitogen-activated protein kinase is activated by ligation of the T or B lymphocyte antigen receptors, Fas or CD40, but suppression of kinase activity does not inhibit apoptosis induced by antigen receptors.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(11):5309-17.
1997: Kumar S; McDonnell P C; Gum R J; Hand A T; Lee J C; Young P R
Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles.
Biochemical and biophysical research communications 1997;235(3):533-8.
1997: Kumar S; Tzimas M N; Griswold D E; Young P R
Expression of ST2, an interleukin-1 receptor homologue, is induced by proinflammatory stimuli.
Biochemical and biophysical research communications 1997;235(3):474-8.
1997: Kwon B S; Tan K B; Ni J; Oh K O; Lee Z H; Kim K K; Kim Y J; Wang S; Gentz R; Yu G L; Harrop J; Lyn S D; Silverman C; Porter T G; Truneh A; Young P R
A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation.
The Journal of biological chemistry 1997;272(22):14272-6.
1997: Young P R; McLaughlin M M; Kumar S; Kassis S; Doyle M L; McNulty D; Gallagher T F; Fisher S; McDonnell P C; Carr S A; Huddleston M J; Seibel G; Porter T G; Livi G P; Adams J L; Lee J C
Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site.
The Journal of biological chemistry 1997;272(18):12116-21.
1997: Foltz I N; Lee J C; Young P R; Schrader J W
Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogen-activated protein kinase pathway.
The Journal of biological chemistry 1997;272(6):3296-301.
1997: Gallagher T F; Seibel G L; Kassis S; Laydon J T; Blumenthal M J; Lee J C; Lee D; Boehm J C; Fier-Thompson S M; Abt J W; Soreson M E; Smietana J M; Hall R F; Garigipati R S; Bender P E; Erhard K F; Krog A J; Hofmann G A; Sheldrake P L; McDonnell P C; Kumar S; Young P R; Adams J L
Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase.
Bioorganic & medicinal chemistry 1997;5(1):49-64.
1996: Doherty M J; Young P R; Cohen P T
Amino acid sequence of a novel protein phosphatase 1 binding protein (R5) which is related to the liver- and muscle-specific glycogen binding subunits of protein phosphatase 1.
FEBS letters 1996;399(3):339-43.
1996: Kumar S; Orsini M J; Lee J C; McDonnell P C; Debouck C; Young P R
Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase.
The Journal of biological chemistry 1996;271(48):30864-9.
1996: Sutherland C L; Heath A W; Pelech S L; Young P R; Gold M R
Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(8):3381-90.
1996: Clifton A D; Young P R; Cohen P
A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress.
FEBS letters 1996;392(3):209-14.
1996: McLaughlin M M; Kumar S; McDonnell P C; Van Horn S; Lee J C; Livi G P; Young P R
Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase.
The Journal of biological chemistry 1996;271(14):8488-92.
1996: Fan L; Young P R; Barone F C; Feuerstein G Z; Smith D H; McIntosh T K
Experimental brain injury induces differential expression of tumor necrosis factor-alpha mRNA in the CNS.
Brain research. Molecular brain research 1996;36(2):287-91.
1996: Einstein R; Jackson J R; D'Alessio K; Lillquist J S; Sathe G; Porter T; Young P R
Type I IL-1 receptor: ligand specific confirmation differences and the role of glycosylation in ligand binding.
Cytokine 1996;8(3):206-13.
1996: Lee J C; Young P R
Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanisms.
Journal of leukocyte biology 1996;59(2):152-7.
1995: Neville L F; Abdullah F; McDonnell P M; Young P R; Feuerstein G Z; Rabinovici R
Mob-1 expression in IL-2-induced ARDS: regulation by TNF-alpha.
The American journal of physiology 1995;269(6 Pt 1):L884-90.
1995: Kumar S; McLaughlin M M; McDonnell P C; Lee J C; Livi G P; Young P R
Human mitogen-activated protein kinase CSBP1, but not CSBP2, complements a hog1 deletion in yeast.
The Journal of biological chemistry 1995;270(49):29043-6.
1995: Kumar S; Minnich M D; Young P R
ST2/T1 protein functionally binds to two secreted proteins from Balb/c 3T3 and human umbilical vein endothelial cells but does not bind interleukin 1.
The Journal of biological chemistry 1995;270(46):27905-13.
1995: McDonnell P C; DiLella A G; Lee J C; Young P R
Localization of the human stress responsive MAP kinase-like CSAIDs binding protein (CSBP) gene to chromosome 6q21.3/21.2.
Genomics 1995;29(1):301-2.
1995: Ben-Baruch A; Xu L; Young P R; Bengali K; Oppenheim J J; Wang J M
Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3.
The Journal of biological chemistry 1995;270(38):22123-8.
1995: Cuenda A; Rouse J; Doza Y N; Meier R; Cohen P; Gallagher T F; Young P R; Lee J C
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1.
FEBS letters 1995;364(2):229-33.
1995: Fan L; Young P R; Barone F C; Feuerstein G Z; Smith D H; McIntosh T K
Experimental brain injury induces expression of interleukin-1 beta mRNA in the rat brain.
Brain research. Molecular brain research 1995;30(1):125-30.
1995: Symons J A; Young P R; Duff G W
Soluble type II interleukin 1 (IL-1) receptor binds and blocks processing of IL-1 beta precursor and loses affinity for IL-1 receptor antagonist.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1714-8.
1995: Wang X; Yue T L; Young P R; Barone F C; Feuerstein G Z
Expression of interleukin-6, c-fos, and zif268 mRNAs in rat ischemic cortex.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1995;15(1):166-71.
1994: Lee J C; Laydon J T; McDonnell P C; Gallagher T F; Kumar S; Green D; McNulty D; Blumenthal M J; Heys J R; Landvatter S W
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis.
Nature 1994;372(6508):739-46.
1994: Eng W K; Faucette L; McLaughlin M M; Cafferkey R; Koltin Y; Morris R A; Young P R; Johnson R K; Livi G P
The yeast FKS1 gene encodes a novel membrane protein, mutations in which confer FK506 and cyclosporin A hypersensitivity and calcineurin-dependent growth.
Gene 1994;151(1-2):61-71.
1994: Lee J C; Prabhakar U; Griswold D E; Dunnington D; Young P R; Badger A
Low-molecular-weight TNF biosynthesis inhibitors: strategies and prospectives.
Circulatory shock 1994;44(3):97-103.
1994: Liu T; Clark R K; McDonnell P C; Young P R; White R F; Barone F C; Feuerstein G Z
Tumor necrosis factor-alpha expression in ischemic neurons.
Stroke; a journal of cerebral circulation 1994;25(7):1481-8.
1994: Cafferkey R; McLaughlin M M; Young P R; Johnson R K; Livi G P
Yeast TOR (DRR) proteins: amino-acid sequence alignment and identification of structural motifs.
Gene 1994;141(1):133-6.
1994: Morton T A; Bennett D B; Appelbaum E R; Cusimano D M; Johanson K O; Matico R E; Young P R; Doyle M; Chaiken I M
Analysis of the interaction between human interleukin-5 and the soluble domain of its receptor using a surface plasmon resonance biosensor.
Journal of molecular recognition : JMR 1994;7(1):47-55.
1993: Liu T; Young P R; McDonnell P C; White R F; Barone F C; Feuerstein G Z
Cytokine-induced neutrophil chemoattractant mRNA expressed in cerebral ischemia.
Neuroscience letters 1993;164(1-2):125-8.
1993: Liu T; McDonnell P C; Young P R; White R F; Siren A L; Hallenbeck J M; Barone F C; Feurestein G Z
Interleukin-1 beta mRNA expression in ischemic rat cortex.
Stroke; a journal of cerebral circulation 1993;24(11):1746-50; discussion 1750-1.
1993: Lee J C; Badger A M; Griswold D E; Dunnington D; Truneh A; Votta B; White J R; Young P R; Bender P E
Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors.
Annals of the New York Academy of Sciences 1993;696():149-70.
1993: Cafferkey R; Young P R; McLaughlin M M; Bergsma D J; Koltin Y; Sathe G M; Faucette L; Eng W K; Johnson R K; Livi G P
Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity.
Molecular and cellular biology 1993;13(10):6012-23.
1993: Camacho N P; Smith D R; Goldman A; Schneider B; Green D; Young P R; Berman H M
Structure of an interleukin-1 beta mutant with reduced bioactivity shows multiple subtle changes in conformation that affect protein-protein recognition.
Biochemistry 1993;32(34):8749-57.
1993: Simon P L; Kumar V; Lillquist J S; Bhatnagar P; Einstein R; Lee J; Porter T; Green D; Sathe G; Young P R
Mapping of neutralizing epitopes and the receptor binding site of human interleukin 1 beta.
The Journal of biological chemistry 1993;268(13):9771-9.
1992: Young P R
Protein hormones and their receptors.
Current opinion in biotechnology 1992;3(4):408-21.
1992: Krasney P A; Young P R
Further aspects of IL-1 beta secretion revealed by transfected monkey kidney cells.
Cytokine 1992;4(2):134-43.
1992: Young P R
The structure of a protein hormone bound to its receptor stimulates some new insights.
Protein engineering 1992;5(2):117-9.
1991: Livi G P; Lillquist J S; Miles L M; Ferrara A; Sathe G M; Simon P L; Meyers C A; Gorman J A; Young P R
Secretion of N-glycosylated interleukin-1 beta in Saccharomyces cerevisiae using a leader peptide from Candida albicans. Effect of N-linked glycosylation on biological activity.
The Journal of biological chemistry 1991;266(23):15348-55.
1991: Hazuda D J; Strickler J; Simon P; Young P R
Structure-function mapping of interleukin 1 precursors. Cleavage leads to a conformational change in the mature protein.
The Journal of biological chemistry 1991;266(11):7081-6.
1990: Livi G P; Ferrara A A; Roskin R; Simon P L; Young P R
Secretion of N-glycosylated human recombinant interleukin-1 alpha in Saccharomyces cerevisiae.
Gene 1990;88(2):297-301.
1990: Hazuda D J; Strickler J; Kueppers F; Simon P L; Young P R
Processing of precursor interleukin 1 beta and inflammatory disease.
The Journal of biological chemistry 1990;265(11):6318-22.
1989: Young P R; Sylvester D
Cloning of rabbit interleukin-1 beta: differential evolution of IL-1 alpha and IL-1 beta proteins.
Protein engineering 1989;2(7):545-51.
1989: Smith M F; Kueppers F R; Young P R; Lee J C
A rapid and quantitative method for the determination of interleukin-1 alpha and -beta mRNA expression in human monocytes and macrophages.
Journal of immunological methods 1989;118(2):265-72.
1989: Hassell A M; Johanson K O; Goodhart P; Young P R; Holskin B P; Carr S A; Roberts G D; Simon P L; Chen M J; Lewis M
Preliminary X-ray crystallography studies of recombinant human interleukin-1 alpha. Purification and structural characterization.
The Journal of biological chemistry 1989;264(9):4948-52.
1989: Lee J C; Simon P L; Young P R
Constitutive and PMA-induced interleukin-1 production by the human astrocytoma cell line T24.
Cellular immunology 1989;118(2):298-311.
1988: Lichenstein H; Brawner M E; Miles L M; Meyers C A; Young P R; Simon P L; Eckhardt T
Secretion of interleukin-1 beta and Escherichia coli galactokinase by Streptomyces lividans.
Journal of bacteriology 1988;170(9):3924-9.
1988: Lillquist J S; Simon P L; Summers M; Jonak Z; Young P R
Structure-activity studies of human IL-1 beta with mature and truncated proteins expressed in Escherichia coli.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(6):1975-81.
1988: Young P R; Hazuda D J; Simon P L
Human interleukin 1 beta is not secreted from hamster fibroblasts when expressed constitutively from a transfected cDNA.
The Journal of cell biology 1988;107(2):447-56.
1988: Hazuda D J; Lee J C; Young P R
The kinetics of interleukin 1 secretion from activated monocytes. Differences between interleukin 1 alpha and interleukin 1 beta.
The Journal of biological chemistry 1988;263(17):8473-9.
1987: Meyers C A; Johanson K O; Miles L M; McDevitt P J; Simon P L; Webb R L; Chen M J; Holskin B P; Lillquist J S; Young P R
Purification and characterization of human recombinant interleukin-1 beta.
The Journal of biological chemistry 1987;262(23):11176-81.
1984: Young P R; Tilghman S M
Induction of alpha-fetoprotein synthesis in differentiating F9 teratocarcinoma cells is accompanied by a genome-wide loss of DNA methylation.
Molecular and cellular biology 1984;4(5):898-907.
1984: Young P R; Litwin S
Determination of the likelihood of repetitive sequences in the alpha-fetoprotein gene.
Journal of molecular biology 1984;173(2):174-6.
1984: Alexander F; Young P R; Tilghman S M
Evolution of the albumin: alpha-fetoprotein ancestral gene from the amplification of a 27 nucleotide sequence.
Journal of molecular biology 1984;173(2):159-73.
1982: Young P R; Scott R W; Hamer D H; Tilghman S M
Construction and expression in vivo of an internally deleted mouse alpha-fetoprotein gene: presence of a transcribed Alu-like repeat within the first intervening sequence.
Nucleic acids research 1982;10(10):3099-116.
1982: Young P R; Nandi U S; Kallenbach N R
Binding of mercury(II) to poly(dA-dT) studied by proton nuclear magnetic resonance.
Biochemistry 1982;21(1):62-6.
1981: Eiferman F A; Young P R; Scott R W; Tilghman S M
Intragenic amplification and divergence in the mouse alpha-fetoprotein gene.
Nature 1981;294(5843):713-8.
1981: Young P R; Ma R I; Marfey P; Kallenbach N R
Frameshift mutagenesis of 9-aminoacridine derivatives in Salmonella typhimurium.
Mutation research 1981;90(1):1-10.
1981: Young P R; Kallenbach N R
Binding of 9-aminoacridine to deoxydinucleoside phosphates of defined sequence: preferences and stereochemistry.
Journal of molecular biology 1981;145(4):785-813.
1981: Berman H M; Young P R
The interaction of intercalating drugs with nucleic acids.
Annual review of biophysics and bioengineering 1981;10():87-114.
1980: Young P R; Kallenbach N R
Site exclusion and sequence specificity in binding of 9-aminoacridine to the deoxytetranucleotide dpApGpCpT.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(11):6453-7.
1978: Young P R; Kallenbach N R
Secondary structure in polyuridylic acid. Non-classical hydrogen bonding and the function of the ribose 2'-hydroxyl group.
Journal of molecular biology 1978;126(3):467-79.

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