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Peter Young

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Zhengying Pan; Heleen Scheerens; Shyr-Jiann Li; Brian E Schultz; Paul A Sprengeler; L Chuck Burrill; Rohan V Mendonca; Michael D Sweeney; Keana C K Scott; Paul G Grothaus; Douglas A Jeffery; Jill M Spoerke; Lee A Honigberg; Peter Young; Stacie A Dalrymple; James Palmer
Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase.
Jeffrey R Spencer; Martin Sendzik; Jason Oeh; Peter Sabbatini; Stacie A Dalrymple; Catherine Magill; Hyunjin M Kim; Penglie Zhang; Neil Squires; Katherine G Moss; Juthamas Sukbuntherng; Doris Graupe; John Eksterowicz; Peter Young; Andrew G Myers; Michael J Green
Evaluation of antitumor properties of novel saframycin analogs in vitro and in vivo.
Joseph J Buggy; Z Alexander Cao; Kathryn E Bass; Erik Verner; Sriram Balasubramanian; Liang Liu; Brian E Schultz; Peter Young; Stacie A Dalrymple
CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo.

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2007: Zhengying Pan; Heleen Scheerens; Shyr-Jiann Li; Brian E Schultz; Paul A Sprengeler; L Chuck Burrill; Rohan V Mendonca; Michael D Sweeney; Keana C K Scott; Paul G Grothaus; Douglas A Jeffery; Jill M Spoerke; Lee A Honigberg; Peter Young; Stacie A Dalrymple; James Palmer
Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase.
ChemMedChem 2007;2(1):58-61.
2006: Jeffrey R Spencer; Martin Sendzik; Jason Oeh; Peter Sabbatini; Stacie A Dalrymple; Catherine Magill; Hyunjin M Kim; Penglie Zhang; Neil Squires; Katherine G Moss; Juthamas Sukbuntherng; Doris Graupe; John Eksterowicz; Peter Young; Andrew G Myers; Michael J Green
Evaluation of antitumor properties of novel saframycin analogs in vitro and in vivo.
Bioorganic & medicinal chemistry letters 2006;16(18):4884-8.
2006: Joseph J Buggy; Z Alexander Cao; Kathryn E Bass; Erik Verner; Sriram Balasubramanian; Liang Liu; Brian E Schultz; Peter Young; Stacie A Dalrymple
CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo.
Molecular cancer therapeutics 2006;5(5):1309-17.
2003: Phillip C C Liu; Reid Huber; Mark D Stow; Karen L Schlingmann; Paul Collier; Boshan Liao; John Link; Timothy C Burn; Gregory F Hollis; Peter Young; Ranjan Mukherjee
Induction of endogenous genes by peroxisome proliferator activated receptor alpha ligands in a human kidney cell line and in vivo.
The Journal of steroid biochemistry and molecular biology 2003;85(1):71-9.
2003: Altaf Kassam; Bowman Miao; Peter Young; Ranjan Mukherjee
Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding.
The Journal of biological chemistry 2003;278(12):10028-32.
2003: Michael Doyle; Shin-Shay Tian; Stephen G Miller; Linda Kessler; Audrey E Baker; Michael Brigham-Burke; Susan B Dillon; Kevin J Duffy; Richard M Keenan; Ruth Lehr; Jon Rosen; Lumelle Schneeweis; John Trill; Peter Young; Juan I Luengo; Peter Lamb
Selective binding and oligomerization of the murine granulocyte colony-stimulating factor receptor by a low molecular weight, nonpeptidyl ligand.
The Journal of biological chemistry 2003;278(11):9426-34.
2002: Xinkang Wang; Lin Xu; Hugh Wang; Peter Young; Matthias Gaestel; Giora Z Feuerstein
Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice.
The Journal of biological chemistry 2002;277(46):43968-72.
2002: Yuan Zhu; Gang Xu; Arun Patel; Megan M McLaughlin; Carol Silverman; Kristin Knecht; Sharon Sweitzer; Xiaotong Li; Peter McDonnell; Rosanna Mirabile; Dawn Zimmerman; Rogely Boyce; Lauren A Tierney; Erding Hu; George P Livi; Bryan Wolf; Sherin S Abdel-Meguid; George D Rose; Aurora Rajeev; Preston Hensley; Michael Briggs; Peter Young
Cloning, expression, and initial characterization of a novel cytokine-like gene family.
Genomics 2002;80(2):144-50.
2002: Ranjan Mukherjee; Shaoxian Sun; Linda Santomenna; Bowman Miao; Harry Walton; Boshan Liao; Kenneth Locke; Ji-Hu Zhang; Sonny H Nguyen; Li Tao Zhang; KATHLEEN MURPHY; Harold O Ross; M X Xia; Christopher Teleha; S-Y Chen; Bernard H Selling; Richard Wynn; Timothy C Burn; Peter Young
Ligand and coactivator recruitment preferences of peroxisome proliferator activated receptor alpha.
The Journal of steroid biochemistry and molecular biology 2002;81(3):217-25.
2002: Reid M Huber; KATHLEEN MURPHY; Bowman Miao; John R Link; Mark R Cunningham; Mark J Rupar; Paul L Gunyuzlu; Thomas F Haws; Altaf Kassam; Francoise Powell; Gregory F Hollis; Peter Young; Ranjan Mukherjee; Timothy C Burn
Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters.
Gene 2002;290(1-2):35-43.
2001: Dong Cheng; Rupalie Lalana Meegalla; Bokang He; Debra Cromley; Jeffrey T Billheimer; Peter Young
Human acyl-CoA:diacylglycerol acyltransferase is a tetrameric protein.
The Biochemical journal 2001;359(Pt 3):707-14.
2001: J E Sims; Martin J H Nicklin; J. Fernando Bazan; Jenny L Barton; S J Busfield; John E Ford; Robert A Kastelein; S Kumar; H Lin; Julio Jose Mulero; J Pan; Y Pan; D E Smith; Peter Young
A new nomenclature for IL-1-family genes.
Trends in immunology 2001;22(10):536-7.
2000: Katsutoshi Ozaki; K Kikly; D Michalovich; Peter Young; Warren J Leonard
Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(21):11439-44.
2000: Shahab Uddin; Fatima Lekmine; N Sharma; Beata Majchrzak; IA Mayer; Peter Young; G M Bokoch; Eleanor N Fish; Leonidas C Platanias
The Rac1/p38 mitogen-activated protein kinase pathway is required for interferon alpha-dependent transcriptional activation but not serine phosphorylation of Stat proteins.
The Journal of biological chemistry 2000;275(36):27634-40.
2000: Sanjay Kumar; PC McDonnell; Ruth Lehr; Lauren A Tierney; MN Tzimas; Don E Griswold; E A Capper; R Tal-Singer; G I Wells; Michael Doyle; Peter Young
Identification and initial characterization of four novel members of the interleukin-1 family.
The Journal of biological chemistry 2000;275(14):10308-14.
2000: G Z Feuerstein; Peter Young
Apoptosis in cardiac diseases: stress- and mitogen-activated signaling pathways.
Cardiovascular research 2000;45(3):560-9.
2000: Preston Hensley; Michael Doyle; David G Myszka; R W Woody; Michael Brigham-Burke; C L Erickson-Miller; C A Griffin; C S Jones; Dean E McNulty; S P O'Brien; BY Amegadzie; L MacKenzie; M D Ryan; Peter Young
Evaluating energetics of erythropoietin ligand binding to homodimerized receptor extracellular domains.
Methods in enzymology 2000;323():177-207.
1999: RJ Gum; Peter Young
Identification of two distinct regions of p38 MAPK required for substrate binding and phosphorylation.
Biochemical and biophysical research communications 1999;266(1):284-9.
1999: Shahab Uddin; Beata Majchrzak; J Woodson; P Arunkumar; YM Alsayed; R Pine; Peter Young; Eleanor N Fish; Leonidas C Platanias
Activation of the p38 mitogen-activated protein kinase by type I interferons.
The Journal of biological chemistry 1999;274(42):30127-31.
1999: Michael P Scheid; IN Foltz; Peter Young; John W Schrader; Vincent Duronio
Ceramide and cyclic adenosine monophosphate (cAMP) induce cAMP response element binding protein phosphorylation via distinct signaling pathways while having opposite effects on myeloid cell survival.
Blood 1999;93(1):217-25.
1998: Lisa A Marshall; Michael Hansbury; Brian J Bolognese; RJ Gum; Peter Young; RJ Mayer
Inhibitors of the p38 mitogen-activated kinase modulate IL-4 induction of low affinity IgE receptor (CD23) in human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(11):6005-13.
1998: JA Harrop; PC McDonnell; Michael Brigham-Burke; SD Lyn; J Minton; KB Tan; K Dede; J Spampanato; Carol Silverman; Preston Hensley; R DiPrinzio; JG Emery; KC Deen; Christopher Eichman; M Chabot-Fletcher; Alemseged Truneh; Peter Young
Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth.
The Journal of biological chemistry 1998;273(42):27548-56.
1998: Z Wang; BJ Canagarajah; J C Boehm; S Kassisà; Melanie H Cobb; Peter Young; Sherin S Abdel-Meguid; J L Adams; Elizabeth J Goldsmith
Structural basis of inhibitor selectivity in MAP kinases.
Structure (London, England : 1993) 1998;6(9):1117-28.
1998: Peter Young
Pharmacological modulation of cytokine action and production through signaling pathways.
Cytokine & growth factor reviews 1998;9(3-4):239-57.
1998: JA Harrop; M Reddy; K Dede; Michael Brigham-Burke; SD Lyn; KB Tan; Carol Silverman; Christopher Eichman; R DiPrinzio; J Spampanato; T Porter; S Holmes; Peter Young; Alemseged Truneh
Antibodies to TR2 (herpesvirus entry mediator), a new member of the TNF receptor superfamily, block T cell proliferation, expression of activation markers, and production of cytokines.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1786-94.
1998: RJ Gum; Megan M McLaughlin; Sanjay Kumar; Z Wang; Michael J Bower; John Lee; Jerry L Adams; George P Livi; E J Goldsmith; Peter Young
Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket.
The Journal of biological chemistry 1998;273(25):15605-10.
1998: JG Emery; P McDonnell; M B Burke; KC Deen; SD Lyn; Carol Silverman; E Dul; Edward R Appelbaum; Christopher Eichman; R DiPrinzio; RA Dodds; Ian E James; M Rosenberg; J C Lee; Peter Young
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.
The Journal of biological chemistry 1998;273(23):14363-7.
1998: John White; Judithann M Lee; Peter Young; R P Hertzberg; Anthony Jurewicz; M A Chaikin; Katherine L Widdowson; James J Foley; Lenox D Martin; Don E Griswold; Henry M Sarau
Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration.
The Journal of biological chemistry 1998;273(17):10095-8.
1997: RA Salmon; IN Foltz; Peter Young; John W Schrader
The p38 mitogen-activated protein kinase is activated by ligation of the T or B lymphocyte antigen receptors, Fas or CD40, but suppression of kinase activity does not inhibit apoptosis induced by antigen receptors.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(11):5309-17.
1997: Sanjay Kumar; PC McDonnell; RJ Gum; A T Hand; John Lee; Peter Young
Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles.
Biochemical and biophysical research communications 1997;235(3):533-8.
1997: Sanjay Kumar; MN Tzimas; Don E Griswold; Peter Young
Expression of ST2, an interleukin-1 receptor homologue, is induced by proinflammatory stimuli.
Biochemical and biophysical research communications 1997;235(3):474-8.
1997: Byoung S Kwon; KB Tan; Jian Ni; KO Oh; Z H Lee; K K Kim; Y J Kim; S Wang; Reiner Gentz; GL Yu; JA Harrop; SD Lyn; Carol Silverman; T G Porter; Alemseged Truneh; Peter Young
A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation.
The Journal of biological chemistry 1997;272(22):14272-6.
1997: Peter Young; Megan M McLaughlin; Sanjay Kumar; Shouki Kassis; Michael Doyle; Dean E McNulty; TF Gallagher; S Fisher; PC McDonnell; Steve Carr; Michael J Huddleston; G Seibel; T G Porter; George P Livi; Jerry L Adams; John Lee
Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site.
The Journal of biological chemistry 1997;272(18):12116-21.
1997: IN Foltz; Junella C Lee; Peter Young; John W Schrader
Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogen-activated protein kinase pathway.
The Journal of biological chemistry 1997;272(6):3296-301.
1997: TF Gallagher; G L Seibel; Shouki Kassis; J T Laydon; M J Blumenthal; John Lee; D Lee; Jeffrey C Boehm; S M Fier-Thompson; J W Abt; M E Soreson; J M Smietana; R F Hall; R S Garigipati; P E Bender; Karl F Erhard; A J Krog; Glenn Hofmann; P L Sheldrake; PC McDonnell; Sanjay Kumar; Peter Young; Jerry L Adams
Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase.
Bioorganic & medicinal chemistry 1997;5(1):49-64.
1996: M J Doherty; Peter Young; Patricia T W Cohen
Amino acid sequence of a novel protein phosphatase 1 binding protein (R5) which is related to the liver- and muscle-specific glycogen binding subunits of protein phosphatase 1.
FEBS letters 1996;399(3):339-43.
1996: S Kumar; M J Orsini; John Lee; P C McDonnell; CM Debouck; Peter Young
Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase.
The Journal of biological chemistry 1996;271(48):30864-9.
1996: C L Sutherland; A W Heath; Steven Pelech; Peter Young; Michael Robert Gold
Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(8):3381-90.
1996: A D Clifton; Peter Young; Philip Cohen
A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress.
FEBS letters 1996;392(3):209-14.
1996: Megan M McLaughlin; S Kumar; P C McDonnell; S Van Horn; John Lee; George P Livi; Peter Young
Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase.
The Journal of biological chemistry 1996;271(14):8488-92.
1996: L Fan; Peter Young; Frank C Barone; G Z Feuerstein; D H Smith; T K McIntosh
Experimental brain injury induces differential expression of tumor necrosis factor-alpha mRNA in the CNS.
Brain research. Molecular brain research 1996;36(2):287-91.
1996: R Einstein; J R Jackson; K D'Alessio; Jay Lillquist; G Sathe; T Porter; Peter Young
Type I IL-1 receptor: ligand specific confirmation differences and the role of glycosylation in ligand binding.
Cytokine 1996;8(3):206-13.
1996: J C Lee; Peter Young
Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanisms.
Journal of leukocyte biology 1996;59(2):152-7.
1995: S Kumar; Megan M McLaughlin; P C McDonnell; John Lee; George P Livi; Peter Young
Human mitogen-activated protein kinase CSBP1, but not CSBP2, complements a hog1 deletion in yeast.
The Journal of biological chemistry 1995;270(49):29043-6.
1995: Lewis F Neville; Fizan Abdullah; P M McDonnell; Peter Young; Giora Z Feuerstein; Reuven Rabinovici
Mob-1 expression in IL-2-induced ARDS: regulation by TNF-alpha.
The American journal of physiology 1995;269(6 Pt 1):L884-90.
1995: S Kumar; M D Minnich; Peter Young
ST2/T1 protein functionally binds to two secreted proteins from Balb/c 3T3 and human umbilical vein endothelial cells but does not bind interleukin 1.
The Journal of biological chemistry 1995;270(46):27905-13.
1995: A Ben-Baruch; L Xu; Peter Young; K Bengali; Joost J Oppenheim; Ji Ming Wang
Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3.
The Journal of biological chemistry 1995;270(38):22123-8.
1995: P C McDonnell; A G DiLella; J C Lee; Peter Young
Localization of the human stress responsive MAP kinase-like CSAIDs binding protein (CSBP) gene to chromosome 6q21.3/21.2.
Genomics 1995;29(1):301-2.
1995: Ana Cuenda; J Rouse; Y N Doza; R Meier; Philip Cohen; T F Gallagher; Peter Young; J C Lee
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1.
FEBS letters 1995;364(2):229-33.
1995: L Fan; Peter Young; Frank C Barone; G Z Feuerstein; D H Smith; T K McIntosh
Experimental brain injury induces expression of interleukin-1 beta mRNA in the rat brain.
Brain research. Molecular brain research 1995;30(1):125-30.
1995: J A Symons; Peter Young; Gordon W Duff
Soluble type II interleukin 1 (IL-1) receptor binds and blocks processing of IL-1 beta precursor and loses affinity for IL-1 receptor antagonist.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1714-8.
1995: X Wang; T L Yue; Peter Young; Frank C Barone; Giora Z Feuerstein
Expression of interleukin-6, c-fos, and zif268 mRNAs in rat ischemic cortex.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1995;15(1):166-71.
1994: W K Eng; L Faucette; Megan M McLaughlin; R Cafferkey; Y Koltin; R A Morris; Peter Young; Randall K Johnson; George P Livi
The yeast FKS1 gene encodes a novel membrane protein, mutations in which confer FK506 and cyclosporin A hypersensitivity and calcineurin-dependent growth.
Gene 1994;151(1-2):61-71.
1994: John Lee; U Prabhakar; Don E Griswold; D Dunnington; Peter Young; AM Badger
Low-molecular-weight TNF biosynthesis inhibitors: strategies and prospectives.
Circulatory shock 1994;44(3):97-103.
1994: T Liu; R K Clark; P C McDonnell; Peter Young; Ray F White; Frank C Barone; Giora Z Feuerstein
Tumor necrosis factor-alpha expression in ischemic neurons.
Stroke; a journal of cerebral circulation 1994;25(7):1481-8.
1994: R Cafferkey; Megan M McLaughlin; Peter Young; Randall K Johnson; George P Livi
Yeast TOR (DRR) proteins: amino-acid sequence alignment and identification of structural motifs.
Gene 1994;141(1):133-6.
1994: TA Morton; D B Bennett; Edward R Appelbaum; D M Cusimano; Kyung O Johanson; R E Matico; Peter Young; Michael Doyle; I M Chaiken
Analysis of the interaction between human interleukin-5 and the soluble domain of its receptor using a surface plasmon resonance biosensor.
Journal of molecular recognition : JMR 1994;7(1):47-55.
1993: T Liu; Peter Young; P C McDonnell; R F White; Frank C Barone; Giora Z Feuerstein
Cytokine-induced neutrophil chemoattractant mRNA expressed in cerebral ischemia.
Neuroscience letters 1993;164(1-2):125-8.
1993: John Lee; AM Badger; Don E Griswold; D Dunnington; A Truneh; Bartholomew Votta; John White; Peter Young; P E Bender
Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors.
Annals of the New York Academy of Sciences 1993;696():149-70.
1993: T Liu; P C McDonnell; Peter Young; Ray F White; A L Siren; J M Hallenbeck; Frank C Barone; G Z Feurestein
Interleukin-1 beta mRNA expression in ischemic rat cortex.
Stroke; a journal of cerebral circulation 1993;24(11):1746-50; discussion 1750-1.
1993: R Cafferkey; Peter Young; Megan M McLaughlin; DJ Bergsma; Y Koltin; G M Sathe; L Faucette; W K Eng; Randall K Johnson; George P Livi
Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity.
Molecular and cellular biology 1993;13(10):6012-23.
1993: Nancy Pleshko Camacho; D R Smith; A Goldman; B Schneider; D Green; Peter Young; Helen M Berman
Structure of an interleukin-1 beta mutant with reduced bioactivity shows multiple subtle changes in conformation that affect protein-protein recognition.
Biochemistry 1993;32(34):8749-57.
1993: P L Simon; V Kumar; Jay Lillquist; P Bhatnagar; R Einstein; J Lee; T Porter; David Green; G Sathe; Peter Young
Mapping of neutralizing epitopes and the receptor binding site of human interleukin 1 beta.
The Journal of biological chemistry 1993;268(13):9771-9.
1992: Peter Young
Protein hormones and their receptors.
Current opinion in biotechnology 1992;3(4):408-21.
1992: P A Krasney; Peter Young
Further aspects of IL-1 beta secretion revealed by transfected monkey kidney cells.
Cytokine 1992;4(2):134-43.
1992: Peter Young
The structure of a protein hormone bound to its receptor stimulates some new insights.
Protein engineering 1992;5(2):117-9.
1991: George P Livi; Jay Lillquist; L M Miles; A Ferrara; G M Sathe; P L Simon; C A Meyers; J A Gorman; Peter Young
Secretion of N-glycosylated interleukin-1 beta in Saccharomyces cerevisiae using a leader peptide from Candida albicans. Effect of N-linked glycosylation on biological activity.
The Journal of biological chemistry 1991;266(23):15348-55.
1991: D J Hazuda; J Strickler; P Simon; Peter Young
Structure-function mapping of interleukin 1 precursors. Cleavage leads to a conformational change in the mature protein.
The Journal of biological chemistry 1991;266(11):7081-6.
1990: George P Livi; A A Ferrara; R Roskin; P L Simon; Peter Young
Secretion of N-glycosylated human recombinant interleukin-1 alpha in Saccharomyces cerevisiae.
Gene 1990;88(2):297-301.
1990: D J Hazuda; J Strickler; F Kueppers; P L Simon; Peter Young
Processing of precursor interleukin 1 beta and inflammatory disease.
The Journal of biological chemistry 1990;265(11):6318-22.
1989: Peter Young; D Sylvester
Cloning of rabbit interleukin-1 beta: differential evolution of IL-1 alpha and IL-1 beta proteins.
Protein engineering 1989;2(7):545-51.
1989: Michael Smith, Jr.; F R Kueppers; Peter Young; J C Lee
A rapid and quantitative method for the determination of interleukin-1 alpha and -beta mRNA expression in human monocytes and macrophages.
Journal of immunological methods 1989;118(2):265-72.
1989: A M Hassell; K O Johanson; P Goodhart; Peter Young; B P Holskin; S A Carr; G D Roberts; P L Simon; M J Chen; M Lewis
Preliminary X-ray crystallography studies of recombinant human interleukin-1 alpha. Purification and structural characterization.
The Journal of biological chemistry 1989;264(9):4948-52.
1989: J C Lee; P L Simon; Peter Young
Constitutive and PMA-induced interleukin-1 production by the human astrocytoma cell line T24.
Cellular immunology 1989;118(2):298-311.
1988: Jay Lillquist; P L Simon; M Summers; Z Jonak; Peter Young
Structure-activity studies of human IL-1 beta with mature and truncated proteins expressed in Escherichia coli.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(6):1975-81.
1988: H Lichenstein; M E Brawner; L M Miles; C A Meyers; Peter Young; P L Simon; T Eckhardt
Secretion of interleukin-1 beta and Escherichia coli galactokinase by Streptomyces lividans.
Journal of bacteriology 1988;170(9):3924-9.
1988: Peter Young; D J Hazuda; P L Simon
Human interleukin 1 beta is not secreted from hamster fibroblasts when expressed constitutively from a transfected cDNA.
The Journal of cell biology 1988;107(2):447-56.
1988: D J Hazuda; J C Lee; Peter Young
The kinetics of interleukin 1 secretion from activated monocytes. Differences between interleukin 1 alpha and interleukin 1 beta.
The Journal of biological chemistry 1988;263(17):8473-9.
1987: C A Meyers; K O Johanson; L M Miles; Patrick J McDevitt; P L Simon; R L Webb; M J Chen; B P Holskin; Jay Lillquist; Peter Young
Purification and characterization of human recombinant interleukin-1 beta.
The Journal of biological chemistry 1987;262(23):11176-81.
1984: Peter Young; S M Tilghman
Induction of alpha-fetoprotein synthesis in differentiating F9 teratocarcinoma cells is accompanied by a genome-wide loss of DNA methylation.
Molecular and cellular biology 1984;4(5):898-907.
1984: Peter Young; S Litwin
Determination of the likelihood of repetitive sequences in the alpha-fetoprotein gene.
Journal of molecular biology 1984;173(2):174-6.
1984: F Alexander; Peter Young; S M Tilghman
Evolution of the albumin: alpha-fetoprotein ancestral gene from the amplification of a 27 nucleotide sequence.
Journal of molecular biology 1984;173(2):159-73.
1982: Peter Young; R W Scott; D H Hamer; S M Tilghman
Construction and expression in vivo of an internally deleted mouse alpha-fetoprotein gene: presence of a transcribed Alu-like repeat within the first intervening sequence.
Nucleic acids research 1982;10(10):3099-116.
1982: Peter Young; U S Nandi; N R Kallenbach
Binding of mercury(II) to poly(dA-dT) studied by proton nuclear magnetic resonance.
Biochemistry 1982;21(1):62-6.
1981: F A Eiferman; Peter Young; R W Scott; Shirley M Tilghman
Intragenic amplification and divergence in the mouse alpha-fetoprotein gene.
Nature 1981;294(5843):713-8.
1981: Peter Young; R I Ma; P Marfey; N R Kallenbach
Frameshift mutagenesis of 9-aminoacridine derivatives in Salmonella typhimurium.
Mutation research 1981;90(1):1-10.
1981: Peter Young; N R Kallenbach
Binding of 9-aminoacridine to deoxydinucleoside phosphates of defined sequence: preferences and stereochemistry.
Journal of molecular biology 1981;145(4):785-813.
1981: Helen Berman; Peter Young
The interaction of intercalating drugs with nucleic acids.
Annual review of biophysics and bioengineering 1981;10():87-114.
1980: Peter Young; N R Kallenbach
Site exclusion and sequence specificity in binding of 9-aminoacridine to the deoxytetranucleotide dpApGpCpT.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(11):6453-7.
1978: Peter Young; N R Kallenbach
Secondary structure in polyuridylic acid. Non-classical hydrogen bonding and the function of the ribose 2'-hydroxyl group.
Journal of molecular biology 1978;126(3):467-79.