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Sugimoto Yasuro

Research Profile

Chemicals & Drugs

Disorders

Breast Neoplasms

Anatomy

Physiology

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Reverse Transcriptase Polymerase Chain Reaction

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TOP 3
Edgar S Díaz-Cruz; G Ian Gallicano; Sugimoto Yasuro; Robert W Brueggemeier; Priscilla A Furth
Comparison of increased aromatase versus ERα in the generation of mammary hyperplasia and cancer.
Maryam B Lustberg; Ewa Mrozek; Stephen P Povoski; Bhuvaneswari Ramaswamy; Amy S Ruppert; Donna R Shiels; Sugimoto Yasuro; Weiqiang Zhao; Rebecca M Ziegler; Robert W Brueggemeier; Rachel M Layman; Amy M Lehman; Charles L Shapiro
Phase II trial of neoadjuvant exemestane in combination with celecoxib in postmenopausal women who have breast cancer.
Weiping Ye; Hsiang-Lin Chang; Li-Shu Wang; Yi-Wen Huang; Sherry Shu; Sugimoto Yasuro; Michael K Dowd; Peter J Wan; Young C Lin
Induction of apoptosis by (-)-gossypol-enriched cottonseed oil in human breast cancer cells.

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All Publications

2011: Edgar S Díaz-Cruz; G Ian Gallicano; Sugimoto Yasuro; Robert W Brueggemeier; Priscilla A Furth
Comparison of increased aromatase versus ERα in the generation of mammary hyperplasia and cancer.
Cancer research 2011;71(16):5477-87.
2011: Maryam B Lustberg; Ewa Mrozek; Stephen P Povoski; Bhuvaneswari Ramaswamy; Amy S Ruppert; Donna R Shiels; Sugimoto Yasuro; Weiqiang Zhao; Rebecca M Ziegler; Robert W Brueggemeier; Rachel M Layman; Amy M Lehman; Charles L Shapiro
Phase II trial of neoadjuvant exemestane in combination with celecoxib in postmenopausal women who have breast cancer.
Clinical breast cancer 2011;11(4):221-7.
2010: Weiping Ye; Hsiang-Lin Chang; Li-Shu Wang; Yi-Wen Huang; Sherry Shu; Sugimoto Yasuro; Michael K Dowd; Peter J Wan; Young C Lin
Induction of apoptosis by (-)-gossypol-enriched cottonseed oil in human breast cancer cells.
International journal of molecular medicine 2010;26(1):113-9.
2010: Sherry T Shu; Sugimoto Yasuro; Suling Liu; Hsiang-Lin Chang; Weiping Ye; Li-Shu Wang; Yi-Wen Huang; Pearlly Yan; Young C Lin
Function and regulatory mechanisms of the candidate tumor suppressor receptor protein tyrosine phosphatase gamma (PTPRG) in breast cancer cells.
Anticancer research 2010;30(6):1937-46.
2010: Yu Zheng; Bo Yu; Wanlop Weecharangsan; Longzhu Piao; Michael Darby; Yicheng Mao; Rumiana Koynova; Xiaojuan Yang; Hong Li; Songlin Xu; L James Lee; Sugimoto Yasuro; Robert W Brueggemeier; Robert J Lee
Transferrin-conjugated lipid-coated PLGA nanoparticles for targeted delivery of aromatase inhibitor 7alpha-APTADD to breast cancer cells.
International journal of pharmaceutics 2010;390(2):234-41.
2010: Robert W Brueggemeier; Bin Su; Michael V Darby; Sugimoto Yasuro
Selective regulation of aromatase expression for drug discovery.
The Journal of steroid biochemistry and molecular biology 2010;118(4-5):207-10.
2009: Hsiang-Lin Chang; Sugimoto Yasuro; Suling Liu; Li-Shu Wang; Yi-Wen Huang; Weiping Ye; Young C Lin
Keratinocyte growth factor (KGF) regulates estrogen receptor-alpha (ER-alpha) expression and cell apoptosis via phosphatidylinositol 3-kinase (PI3K)/Akt pathway in human breast cancer cells.
Anticancer research 2009;29(8):3195-205.
2007: Robert W Brueggemeier; Bin Su; Sugimoto Yasuro; Edgar S Díaz-Cruz; Danyetta D Davis
Aromatase and COX in breast cancer: enzyme inhibitors and beyond.
The Journal of steroid biochemistry and molecular biology 2007;106(1-5):16-23.
2007: Weiping Ye; Hsiang-Lin Chang; Li-Shu Wang; Yi-Wen Huang; Sherry Shu; Michael K Dowd; Peter J Wan; Sugimoto Yasuro; Young C Lin
Modulation of multidrug resistance gene expression in human breast cancer cells by (-)-gossypol-enriched cottonseed oil.
Anticancer research 2007;27(1A):107-16.
2006: Yi-Wen Huang; Li-Shu Wang; Hsiang-Lin Chang; Weiping Ye; Sugimoto Yasuro; Michael K Dowd; Peter J Wan; Young C Lin
Effects of serum on (-)-gossypol-suppressed growth in human prostate cancer cells.
Anticancer research 2006;26(5A):3613-20.
2006: Yi-Wen Huang; Li-Shu Wang; Hsiang-Lin Chang; Weiping Ye; Sherry Shu; Sugimoto Yasuro; Young C Lin
Effect of keratinocyte growth factor on cell viability in primary cultured human prostate cancer stromal cells.
The Journal of steroid biochemistry and molecular biology 2006;100(1-3):24-33.
2006: Hsiang-Lin Chang; Sugimoto Yasuro; Suling Liu; Weiping Ye; Li-Shu Wang; Yi-Wen Huang; Young C Lin
Keratinocyte growth factor (KGF) induces tamoxifen (Tam) resistance in human breast cancer MCF-7 cells.
Anticancer research 2006;26(3A):1773-84.
2006: Li-Shu Wang; Yi-Wen Huang; Suling Liu; Hsiang-Lin Chang; Weiping Ye; Sherry Shu; Sugimoto Yasuro; Julie A Funk; Daniel D Smeaks; Lawrence N Hill; Young C Lin
Conjugated linoleic acid (CLA) modulates prostaglandin E2 (PGE2) signaling in canine mammary cells.
Anticancer research 2006;26(2A):889-98.
2006: Li-Shu Wang; Yi-Wen Huang; Sugimoto Yasuro; Suling Liu; Hsiang-Lin Chang; Weiping Ye; Sherry Shu; Young C Lin
Conjugated linoleic acid (CLA) up-regulates the estrogen-regulated cancer suppressor gene, protein tyrosine phosphatase gamma (PTPgama), in human breast cells.
Anticancer research 2006;26(1A):27-34.
2005: Jiahua Jiang; Hsiang-Lin Chang; Sugimoto Yasuro; Young C Lin
Effects of age on growth and ERbeta mRNA expression of canine prostatic cells.
Anticancer research 2005;25(6B):4081-90.
2005: Li-Shu Wang; Yi-Wen Huang; Sugimoto Yasuro; Suling Liu; Hsiang-Lin Chang; Weiping Ye; Sherry Shu; Young C Lin
Effects of human breast stromal cells on conjugated linoleic acid (CLA) modulated vascular endothelial growth factor-A (VEGF-A) expression in MCF-7 cells.
Anticancer research 2005;25(6B):4061-8.
2005: Robert W Brueggemeier; Edgar S Díaz-Cruz; Pui-Kai Li; Sugimoto Yasuro; Young C Lin; Charles L Shapiro
Translational studies on aromatase, cyclooxygenases, and enzyme inhibitors in breast cancer.
The Journal of steroid biochemistry and molecular biology 2005;95(1-5):129-36.
2004: Suling Liu; Sugimoto Yasuro; Claudio Sorio; Cristina Tecchio; Young C Lin
Function analysis of estrogenically regulated protein tyrosine phosphatase gamma (PTPgamma) in human breast cancer cell line MCF-7.
Oncogene 2004;23(6):1256-62.
2004: Jiahua Jiang; Sugimoto Yasuro; Suling Liu; Hsiang-Lin Chang; Kah-Young Park; Samuel K Kulp; Young C Lin
The inhibitory effects of gossypol on human prostate cancer cells-PC3 are associated with transforming growth factor beta1 (TGFbeta1) signal transduction pathway.
Anticancer research 2004;24(1):91-100.
2002: Suling Liu; Sugimoto Yasuro; Samuel K Kulp; Jiahua Jiang; Hsiang-Lin Chang; Kah-Young Park; Yoko Kashida; Young C Lin
Estrogenic down-regulation of protein tyrosine phosphatase gamma (PTP gamma) in human breast is associated with estrogen receptor alpha.
Anticancer research 2002;22(6C):3917-23.
2002: Jiahua Jiang; Pradip K Ghosh; Samuel K Kulp; Sugimoto Yasuro; Suling Liu; Jan Czekajewski; Hsiang-Lin Chang; Young C Lin
Effects of gossypol on O2 consumption and CO2 production in human prostate cancer cells.
Anticancer research 2002;22(3):1491-6.
2002: Suling Liu; Samuel K Kulp; Sugimoto Yasuro; Jiahua Jiang; Hsiang-Lin Chang; Michael K Dowd; Peter J Wan; Young C Lin
The (-)-enantiomer of gossypol possesses higher anticancer potency than racemic gossypol in human breast cancer.
Anticancer research 2002;22(1A):33-8.
2002: Suling Liu; Samuel K Kulp; Sugimoto Yasuro; Jiahua Jiang; Hsiang-Lin Chang; Young C Lin
Involvement of breast epithelial-stromal interactions in the regulation of protein tyrosine phosphatase-gamma (PTPgamma) mRNA expression by estrogenically active agents.
Breast cancer research and treatment 2002;71(1):21-35.
2000: Jiahua Jiang; Samuel K Kulp; Sugimoto Yasuro; Suling Liu; Young C Lin
The effects of gossypol on the invasiveness of MAT-LyLu cells and MAT-LyLu cells from the metastasized lungs of MAT-LyLu-bearing Copenhagen rats.
Anticancer research 2000;20(6B):4591-7.
2000: J Zheng; Samuel K Kulp; Y Zhang; Sugimoto Yasuro; MA Dayton; M V Govindan; Robert W Brueggemeier; Young C Lin
17 beta-estradiol-regulated expression of protein tyrosine phosphatase gamma gene in cultured human normal breast and breast cancer cells.
Anticancer research 2000;20(1A):11-9.
1999: Eric A G Blomme; Sugimoto Yasuro; Young C Lin; Charles C Capen; Thomas J Rosol
Parathyroid hormone-related protein is a positive regulator of keratinocyte growth factor expression by normal dermal fibroblasts.
Molecular and cellular endocrinology 1999;152(1-2):189-97.
1998: Y Zhang; Samuel K Kulp; Sugimoto Yasuro; Robert W Brueggemeier; Young C Lin
The (-)-enantiomer of gossypol inhibits proliferation of stromal cells derived from human breast adipose tissues by enhancing transforming growth factor beta1 production.
International journal of oncology 1998;13(6):1291-7.
1998: Y Zhang; Samuel K Kulp; Sugimoto Yasuro; William B Farrar; Robert W Brueggemeier; Young C Lin
Keratinocyte growth factor (KGF) induces aromatase activity in cultured MCF-7 human breast cancer cells.
Anticancer research 1998;18(4A):2541-6.
1998: Eric A G Blomme; Sugimoto Yasuro; Laurie K McCauley; Young C Lin; Charles C Capen; Thomas J Rosol
Stromal and epithelial cells of the canine prostate express parathyroid hormone-related protein, but not the PTH/PTHrP receptor.
The Prostate 1998;36(2):110-20.
1998: Y Zhang; Sugimoto Yasuro; Samuel K Kulp; William B Farrar; Robert W Brueggemeier; Young C Lin
Estrogen-induced keratinocyte growth factor mRNA expression in normal and cancerous human breast cells.
Oncology reports 1998;5(3):577-83.
1997: F Shidaifat; H Canatan; Samuel K Kulp; Sugimoto Yasuro; Y Zhang; Robert W Brueggemeier; W J Somers; WY Chang; H C Wang; Young C Lin
Gossypol arrests human benign prostatic hyperplastic cell growth at G0/G1 phase of the cell cycle.
Anticancer research 1997;17(2A):1003-9.
1997: WY Chang; Sugimoto Yasuro; F Shidaifat; Samuel K Kulp; H Canatan; Young C Lin
Gossypol induces spermidine/spermine N1-acetyltransferase in canine prostate epithelial cells.
Biochemical and biophysical research communications 1997;231(2):383-8.
1996: WY Chang; Samuel K Kulp; Sugimoto Yasuro; H Canatan; F Shidaifat; Nongnuch Inpanbutr; Young C Lin
Detection of keratinocyte growth factor (KGF) messenger ribonucleic acid and immunolocalization of KGF in the canine testis.
Endocrine 1996;5(3):247-55.
1996: F Shidaifat; H Canatan; Samuel K Kulp; Sugimoto Yasuro; W Y Chang; Y Zhang; Robert W Brueggemeier; W J Somers; Young C Lin
Inhibition of human prostate cancer cells growth by gossypol is associated with stimulation of transforming growth factor-beta.
Cancer letters 1996;107(1):37-44.
1996: W Y Chang; F Shidaifat; C J Chang; Samuel K Kulp; Sugimoto Yasuro; H Canatan; Robert W Brueggemeier; Young C Lin
Experimentally-induced prostatic hyperplasia in young beagles: a model to evaluate the chemotherapeutic effects of gossypol.
Research communications in molecular pathology and pharmacology 1996;92(3):341-60.
1996: H Canatan; W Y Chang; Sugimoto Yasuro; F Shidaifat; Samuel K Kulp; Robert W Brueggemeier; Young C Lin
Keratinocyte growth factor (KGF/FGF-7) has a paracrine role in canine prostate: molecular cloning of mRNA encoding canine KGF.
DNA and cell biology 1996;15(3):247-54.
1995: Sugimoto Yasuro; I López-Solache; Fernand Labrie; Van Luu-The
Cations inhibit specifically type I 5 alpha-reductase found in human skin.
The Journal of investigative dermatology 1995;104(5):775-8.
1994: Van Luu-The; Sugimoto Yasuro; L Puy; Y Labrie; I Lopez Solache; M Singh; Fernand Labrie
Characterization, expression, and immunohistochemical localization of 5 alpha-reductase in human skin.
The Journal of investigative dermatology 1994;102(2):221-6.
1992: Fernand Labrie; Sugimoto Yasuro; Van Luu-The; Jacques Simard; Y Lachance; D Bachvarov; G Leblanc; Francine Durocher; N Paquet
Structure of human type II 5 alpha-reductase gene.
Endocrinology 1992;131(3):1571-3.
1990: Sugimoto Yasuro; M Yoshida; B Tamaoki
Purification of 5 beta-reductase from hepatic cytosol fraction of chicken.
The Journal of steroid biochemistry and molecular biology 1990;37(5):717-24.
1990: Sugimoto Yasuro; Y Ohta; T Morikawa; T Yamashita; M Yoshida; B Tamaoki
In vitro metabolism of testosterone on hepatic tissue of chicken (Gallus domesticus).
Journal of steroid biochemistry 1990;35(2):271-9.
1990: Hiroshi Inano; H Ishii-Ohba; Sugimoto Yasuro; Y Ohta; T Morikawa; M Yoshida; B Tamaoki
Purification and properties of enzymes related to steroid hormone synthesis.
Annals of the New York Academy of Sciences 1990;595():17-25.