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Pascal Pineau

Research Profile

Disorders

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Morocco

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Hepatitis B virus

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Ikram Brahim; Sayeh Ezzikouri; El Mostafa Mtairag; Salwa Nadir; Pascal Pineau; Rhimou Alaoui; Soumaya Benjelloun
Amino acid substitutions in the Hepatitis C virus core region of genotype 1b in Moroccan patients.
Abdellah Akil; Mustapha Benazzouz; Rajaa Afifi; Aziz Benjouad; Anne Dejean; Ama Gassama Diagne; Abdellah Essaid El Feydi; Sayeh Ezzikouri; Pascal Pineau; Soumaya Benjelloun
Associations of genetic variants in the transcriptional coactivators EP300 and PCAF with hepatocellular carcinoma.
Agnès Marchio; Abdellah Akil; Anne Dejean; Benoît Terris; Pascal Pineau
Insertion/deletion polymorphisms are convenient and reliable markers to assess chromosomal instability in human tumors.

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All Publications

2013: Ikram Brahim; Sayeh Ezzikouri; El Mostafa Mtairag; Salwa Nadir; Pascal Pineau; Rhimou Alaoui; Soumaya Benjelloun
Amino acid substitutions in the Hepatitis C virus core region of genotype 1b in Moroccan patients.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2013;14():102-4.
2012: Abdellah Akil; Mustapha Benazzouz; Rajaa Afifi; Aziz Benjouad; Anne Dejean; Ama Gassama Diagne; Abdellah Essaid El Feydi; Sayeh Ezzikouri; Pascal Pineau; Soumaya Benjelloun
Associations of genetic variants in the transcriptional coactivators EP300 and PCAF with hepatocellular carcinoma.
Cancer epidemiology 2012;36(5):e300-5.
2012: Agnès Marchio; Abdellah Akil; Anne Dejean; Benoît Terris; Pascal Pineau
Insertion/deletion polymorphisms are convenient and reliable markers to assess chromosomal instability in human tumors.
The International journal of biological markers 2012;27(3):e232-40.
2012: Ikram Brahim; Sayeh Ezzikouri; Abdelouhad El Malki; El Mostafa Mtairag; Salwa Nadir; Richard Njouom; Pascal Pineau; Régis Pouillot; Abdelah Akil; Rhimou Alaoui; Soumaya Benjelloun
Morocco underwent a drift of circulating hepatitis C virus subtypes in recent decades.
Archives of virology 2012;157(3):515-20.
2011: Sayeh Ezzikouri; Mostafa Kandil; Bouchra Kitab; Ababou Mostafa; Sellama Nadifi; Pascal Pineau; Khadija Rebbani; Rajae Afifi; Mustapha Benazzouz; Ikram Brahim; Abdellah Essaid El Feydi; Soumaya Benjelloun
Influence of mutation of the HFE gene on the progression of chronic viral hepatitis B and C in Moroccan patients.
Journal of medical virology 2011;83(12):2096-102.
2011: Rodolphe Suspène; Marie-Ming Aynaud; Denise Guétard; Michel Henry; Grace Eckhoff; Agnès Marchio; Pascal Pineau; Anne Dejean; Jean-Pierre Vartanian; Simon Wain-Hobson
Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(12):4858-63.
2010: Jean-Pierre Vartanian; Michel Henry; Agnès Marchio; Rodolphe Suspène; Marie-Ming Aynaud; Denise Guétard; Minerva Cervantes-Gonzalez; Carlo Battiston; Vincenzo Mazzaferro; Pascal Pineau; Anne Dejean; Simon Wain-Hobson
Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis.
PLoS pathogens 2010;6(5):e1000928.
2010: Pascal Pineau; Stefano Volinia; Katherine McJunkin; Agnès Marchio; Carlo Battiston; Benoît Terris; Vincenzo Mazzaferro; Scott W Lowe; Carlo M Croce; Anne Dejean
miR-221 overexpression contributes to liver tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(1):264-9.
2009: Oliver Bischof; Anne Dejean; Pascal Pineau
[A review of cellular senescence: friend or foe of tumorigenesis?].
Médecine sciences : M/S 2009;25(2):153-60.
2009: Sayeh Ezzikouri; Abdellah Essaid El Feydi; Rajae Afifi; Latifa El Kihal; Mustapha Benazzouz; Mohammed Hassar; Agnès Marchio; Pascal Pineau; Soumaya Benjelloun
MDM2 SNP309T>G polymorphism and risk of hepatocellular carcinoma: a case-control analysis in a Moroccan population.
Cancer detection and prevention 2009;32(5-6):380-5.
2008: Pascal Pineau; Agnès Marchio; Carlo Battiston; Emilie Cordina; Alessandro Russo; Benoît Terris; Lun-Xiu Qin; Bruno Turlin; Zhao-You Tang; Vincenzo Mazzaferro; Anne Dejean
Chromosome instability in human hepatocellular carcinoma depends on p53 status and aflatoxin exposure.
Mutation research 2008;653(1-2):6-13.
2008: Sayeh Ezzikouri; Isabelle Chemin; Abdelaziz Chafik; Lahsen Wakrim; Jalal Nourlil; Abdelouhad El Malki; Agnès Marchio; Anne Dejean; Mohammed Hassar; Christian Trepo; Pascal Pineau; Soumaya Benjelloun
Genotype determination in Moroccan hepatitis B chronic carriers.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2008;8(3):306-12.
2008: Sayeh Ezzikouri; Abdellah Essaid El Feydi; Latifa El Kihal; Rajae Afifi; Mustapha Benazzouz; Mohammed Hassar; Abdelaziz Chafik; Pascal Pineau; Soumaya Benjelloun
Prevalence of common HFE and SERPINA1 mutations in patients with hepatocellular carcinoma in a Moroccan population.
Archives of medical research 2008;39(2):236-41.
2008: Sayeh Ezzikouri; Abdellah Essaid El Feydi; Abdelaziz Chafik; Rajae Afifi; Latifa El Kihal; Mustapha Benazzouz; Mohammed Hassar; Pascal Pineau; Soumaya Benjelloun
Genetic polymorphism in the manganese superoxide dismutase gene is associated with an increased risk for hepatocellular carcinoma in HCV-infected Moroccan patients.
Mutation research 2008;649(1-2):1-6.
2007: Sayeh Ezzikouri; Abdellah Essaid El Feydi; Abdelaziz Chafik; Mustapha Benazzouz; Latifa El Kihal; Rajae Afifi; Mohammed Hassar; Pascal Pineau; Soumaya Benjelloun
The Pro variant of the p53 codon 72 polymorphism is associated with hepatocellular carcinoma in Moroccan population.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(9):748-54.
2007: Pascal Pineau; Sayeh Ezzikouri; Agnès Marchio; Mustapha Benazzouz; E Cordina; Rajae Afifi; Latifa Elkihal; Mohamed Tahar Khalfallah; Hafedh Mestiri; S Tebbal; S Berkane; N Debzi; Hinda Triki; Anne Dejean; F Iguer; Olfa Bahri; A E E Essaid El Feydi; S Benjelloun
Genomic stability prevails in North-African hepatocellular carcinomas.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2007;39(7):671-7.
2007: Claire-Angélique Renard; Charlotte Labalette; Carolina Armengol; Delphine Cougot; Yu Wei; Stefano Cairo; Pascal Pineau; Christine Neuveut; Aurélien de Reyniès; Anne Dejean; Christine Perret; Marie Annick Buendia
Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer.
Cancer research 2007;67(3):901-10.
2006: Mélanie Di Benedetto; Ivan Bièche; Frédérique Deshayes; Sophie Vacher; Sandrine Nouet; V Collura; Isabell Seitz; Simon Louis; Pascal Pineau; Delphine Amsellem-Ouazana; Pierre-Olivier Couraud; A Donny Strosberg; D Stoppa-Lyonnet; Rosette Lidereau; Clara Nahmias
Structural organization and expression of human MTUS1, a candidate 8p22 tumor suppressor gene encoding a family of angiotensin II AT2 receptor-interacting proteins, ATIP.
Gene 2006;380(2):127-36.
2006: Mélanie Di Benedetto; Pascal Pineau; Sandrine Nouet; S Berhouet; Isabell Seitz; Simon Louis; Anne Dejean; Pierre-Olivier Couraud; A Donny Strosberg; D Stoppa-Lyonnet; Clara Nahmias
Mutation analysis of the 8p22 candidate tumor suppressor gene ATIP/MTUS1 in hepatocellular carcinoma.
Molecular and cellular endocrinology 2006;252(1-2):207-15.
2005: Pascal Pineau; Michel Henry; Rodolphe Suspène; Agnès Marchio; Agnes Dettai; Régis Debruyne; Thierry Petit; Alexis Lécu; Pierre Moisson; Anne Dejean; Simon Wain-Hobson; Jean-Pierre Vartanian
A universal primer set for PCR amplification of nuclear histone H4 genes from all animal species.
Molecular biology and evolution 2005;22(3):582-8.
2003: Pascal Pineau; Agnès Marchio; Emilie Cordina; Pierre Tiollais; Anne Dejean
Homozygous deletions scanning in tumor cell lines detects previously unsuspected loci.
International journal of cancer. Journal international du cancer 2003;106(2):216-23.
2003: Pascal Pineau; Agnès Marchio; Seishi Nagamori; Shuichi Seki; Pierre Tiollais; Anne Dejean
Homozygous deletion scanning in hepatobiliary tumor cell lines reveals alternative pathways for liver carcinogenesis.
Hepatology (Baltimore, Md.) 2003;37(4):852-61.
2003: Cheng Liao; Mu-Jun Zhao; Jing Zhao; Hai Song; Pascal Pineau; Agnès Marchio; Anne Dejean; Pierre Tiollais; Hong-Yang Wang; Tsai-Ping Li
Mutation analysis of novel human liver-related putative tumor suppressor gene in hepatocellular carcinoma.
World journal of gastroenterology : WJG 2003;9(1):89-93.
2002: Jean-Pierre Vartanian; Pascal Pineau; Michel Henry; William D Hamilton; Martin N Muller; Richard W Wrangham; Simon Wain-Hobson
Identification of a hepatitis B virus genome in wild chimpanzees (Pan troglodytes schweinfurthi) from East Africa indicates a wide geographical dispersion among equatorial African primates.
Journal of virology 2002;76(21):11155-8.
2001: Agnès Marchio; Benoît Terris; Mounira Meddeb; Pascal Pineau; A Duverger; Pierre Tiollais; Alain BERNHEIM; Anne Dejean
Chromosomal abnormalities in liver cell dysplasia detected by comparative genomic hybridisation.
Molecular pathology : MP 2001;54(4):270-4.
2000: Agnès Marchio; Pascal Pineau; Mounira Meddeb; Benoît Terris; Pierre Tiollais; Alain BERNHEIM; Anne Dejean
Distinct chromosomal abnormality pattern in primary liver cancer of non-B, non-C patients.
Oncogene 2000;19(33):3733-8.
2000: Marie-Pierre Bralet; Jean-Marc Régimbeau; Pascal Pineau; S Dubois; G Loas; F Degos; Dominique Valla; Jacques Belghiti; Claude Degott; Benoît Terris
Hepatocellular carcinoma occurring in nonfibrotic liver: epidemiologic and histopathologic analysis of 80 French cases.
Hepatology (Baltimore, Md.) 2000;32(2):200-4.
2000: Pascal Pineau; Marie Annick Buendia
Studies of genetic defects in hepatocellular carcinoma: recent outcomes and new challenges.
Journal of hepatology 2000;33(1):152-6.
2000: Pascal Pineau; Mounira Meddeb; R Raselli; L X Qin; Benoît Terris; Z Y Tang; Pierre Tiollais; V Mazzaferro; Anne Dejean
Effect of TT virus infection on hepatocellular carcinoma development: results of a Euro-Asian survey.
The Journal of infectious diseases 2000;181(3):1138-42.
1999: Benoît Terris; Pascal Pineau; L Bregeaud; Dominique Valla; Jacques Belghiti; Pierre Tiollais; Claude Degott; Anne Dejean
Close correlation between beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas.
Oncogene 1999;18(47):6583-8.
1999: Pascal Pineau; H Nagai; Sylvie Prigent; Yu Wei; G Gyapay; Jean Weissenbach; Pierre Tiollais; Marie Annick Buendia; Anne Dejean
Identification of three distinct regions of allelic deletions on the short arm of chromosome 8 in hepatocellular carcinoma.
Oncogene 1999;18(20):3127-34.
1998: Pascal Pineau; Agnès Marchio; M G Mattei; W H Kim; J K Youn; Pierre Tiollais; Anne Dejean
Extensive analysis of duplicated-inverted hepatitis B virus integrations in human hepatocellular carcinoma.
The Journal of general virology 1998;79 ( Pt 3)():591-600.
1998: Pierre Tiollais; Pascal Pineau; Y Wei; Anne Dejean; Marie Annick Buendia
[Hepatitis B virus and hepatocellular carcinoma].
Bulletin de l'Académie nationale de médecine 1998;182(1):73-7; discussion 77-8.
1997: H Nagai; Pascal Pineau; Pierre Tiollais; Marie Annick Buendia; Anne Dejean
Comprehensive allelotyping of human hepatocellular carcinoma.
Oncogene 1997;14(24):2927-33.
1997: Agnès Marchio; Mounira Meddeb; Pascal Pineau; Gisèle Danglot; Pierre Tiollais; Alain BERNHEIM; Anne Dejean
Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization.
Genes, chromosomes & cancer 1997;18(1):59-65.
1996: Pascal Pineau; Agnès Marchio; B Terris; M G Mattei; Z X Tu; Pierre Tiollais; Anne Dejean
A t(3;8) chromosomal translocation associated with hepatitis B virus intergration involves the carboxypeptidase N locus.
Journal of virology 1996;70(10):7280-4.