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Mark Estacion

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Publications

TOP 3
Yang Yang; Sulayman D Dib-Hajj; Mark Estacion; Stephen G Waxman
Molecular Architecture of a Sodium Channel S6 Helix: RADIAL TUNING OF THE VOLTAGE-GATED SODIUM CHANNEL 1.7 ACTIVATION GATE.
Mark Estacion; Zhimiao Lin; Lynda Tyrrell; Yong Yang; Yang Yang; Sulayman D Dib-Hajj; Stephen G Waxman
A new Nav1.7 mutation in an erythromelalgia patient.
Mark Estacion; Stephen G Waxman
The response of Na(V)1.3 sodium channels to ramp stimuli: multiple components and mechanisms.

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All Publications

2013: Yang Yang; Sulayman D Dib-Hajj; Mark Estacion; Stephen G Waxman
Molecular Architecture of a Sodium Channel S6 Helix: RADIAL TUNING OF THE VOLTAGE-GATED SODIUM CHANNEL 1.7 ACTIVATION GATE.
The Journal of biological chemistry 2013;288(19):13741-7.
2013: Mark Estacion; Zhimiao Lin; Lynda Tyrrell; Yong Yang; Yang Yang; Sulayman D Dib-Hajj; Stephen G Waxman
A new Nav1.7 mutation in an erythromelalgia patient.
Biochemical and biophysical research communications 2013;432(1):99-104.
2013: Mark Estacion; Stephen G Waxman
The response of Na(V)1.3 sodium channels to ramp stimuli: multiple components and mechanisms.
Journal of neurophysiology 2013;109(2):306-14.
2012: Yang Yang; Jian Zhang; Yang Zhang; Sulayman D Dib-Hajj; Mark Estacion; Lynda Tyrrell; Stephen G Waxman
Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Na(V)1.7 mutant channel.
Nature communications 2012;3():1186.
2012: Catharina G Faber; Monique M Gerrits; Chongyang Han; Janneke G J Hoeijmakers; Giuseppe Lauria; Hye-Sook Ahn; Xiaoyang Cheng; Jin-Sung Choi; Sulayman Dib-Hajj; Joost P H Drenth; Mark Estacion; Els K Vanhoutte; Stephen G Waxman; I S J Merkies
Gain of function Naν1.7 mutations in idiopathic small fiber neuropathy.
Annals of neurology 2012;71(1):26-39.
2010: Mark Estacion; Andreas Gasser; Sulayman D Dib-Hajj; Stephen G Waxman
A sodium channel mutation linked to epilepsy increases ramp and persistent current of Nav1.3 and induces hyperexcitability in hippocampal neurons.
Experimental neurology 2010;224(2):362-8.
2010: Mark Estacion; Stephen G Waxman; Sulayman D Dib-Hajj
Effects of ranolazine on wild-type and mutant hNav1.7 channels and on DRG neuron excitability.
Molecular pain 2010;6():35.
2009: Mark Estacion; T Patrick Harty; Jin-Sung Choi; Lynda Tyrrell; Sulayman D Dib-Hajj; Stephen G Waxman
A sodium channel gene SCN9A polymorphism that increases nociceptor excitability.
Annals of neurology 2009;66(6):862-6.
2009: William G Sinkins; Mark Estacion; Vikram Prasad; Monu Goel; Gary E Shull; Diana L Kunze; William Schilling
Maitotoxin converts the plasmalemmal Ca(2+) pump into a Ca(2+)-permeable nonselective cation channel.
American journal of physiology. Cell physiology 2009;297(6):C1533-43.
2009: Tanya Z Fischer; Elaine S Gilmore; Mark Estacion; Emmanuella Eastman; Sean Taylor; Michel Melanson; Sulayman D Dib-Hajj; Stephen G Waxman
A novel Nav1.7 mutation producing carbamazepine-responsive erythromelalgia.
Annals of neurology 2009;65(6):733-41.
2009: Theodore R Cummins; Anthony M Rush; Mark Estacion; Sulayman D Dib-Hajj; Stephen G Waxman
Voltage-clamp and current-clamp recordings from mammalian DRG neurons.
Nature protocols 2009;4(8):1103-12.
2008: Mark Estacion; Sulayman D Dib-Hajj; P J Benke; Rene H M Te Morsche; E M Eastman; Lawrence J Macala; J P H Drenth; Stephen G Waxman
NaV1.7 gain-of-function mutations as a continuum: A1632E displays physiological changes associated with erythromelalgia and paroxysmal extreme pain disorder mutations and produces symptoms of both disorders.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(43):11079-88.
2008: Stephen G Waxman; Mark Estacion
Nav1.9, G-proteins, and nociceptors.
The Journal of physiology 2008;586(4):917-8.
2008: Sulayman D Dib-Hajj; Mark Estacion; brian jarecki; Lynda Tyrrell; Tanya Z Fischer; Mark Lawden; Theodore R Cummins; Stephen G Waxman
Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable.
Molecular pain 2008;4():37.
2006: William Schilling; Deborah Snyder; William G Sinkins; Mark Estacion
Palytoxin-induced cell death cascade in bovine aortic endothelial cells.
American journal of physiology. Cell physiology 2006;291(4):C657-67.
2006: Monu Goel; William G Sinkins; Cheng-Di Zuo; Mark Estacion; William Schilling
Identification and localization of TRPC channels in the rat kidney.
American journal of physiology. Renal physiology 2006;290(5):F1241-52.
2006: Mark Estacion; William G Sinkins; Stephen W Jones; Milana A B Applegate; William Schilling
Human TRPC6 expressed in HEK 293 cells forms non-selective cation channels with limited Ca2+ permeability.
The Journal of physiology 2006;572(Pt 2):359-77.
2004: Philip A Verhoef; Sylvia B Kertesy; Mark Estacion; William Schilling; George R Dubyak
Maitotoxin induces biphasic interleukin-1beta secretion and membrane blebbing in murine macrophages.
Molecular pharmacology 2004;66(4):909-20.
2004: William G Sinkins; Monu Goel; Mark Estacion; William Schilling
Association of immunophilins with mammalian TRPC channels.
The Journal of biological chemistry 2004;279(33):34521-9.
2004: Brian J Wisnoskey; Mark Estacion; William Schilling
Maitotoxin-induced cell death cascade in bovine aortic endothelial cells: divalent cation specificity and selectivity.
American journal of physiology. Cell physiology 2004;287(2):C345-56.
2004: Mark Estacion; Su Li; William G Sinkins; Martin Gosling; Parmjit Bahra; Chris Poll; John Westwick; William Schilling
Activation of human TRPC6 channels by receptor stimulation.
The Journal of biological chemistry 2004;279(21):22047-56.
2003: Philip A Verhoef; Mark Estacion; William Schilling; George R Dubyak
P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1 beta release.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5728-38.
2003: Mark Estacion; Justin S Weinberg; William G Sinkins; William Schilling
Blockade of maitotoxin-induced endothelial cell lysis by glycine and L-alanine.
American journal of physiology. Cell physiology 2003;284(4):C1006-20.
2002: Mark Estacion; William Schilling
Blockade of maitotoxin-induced oncotic cell death reveals zeiosis.
BMC physiology 2002;2():2.
2001: Monu Goel; R Garcia; Mark Estacion; William Schilling
Regulation of Drosophila TRPL channels by immunophilin FKBP59.
The Journal of biological chemistry 2001;276(42):38762-73.
2001: Mark Estacion; William Schilling
Maitotoxin-induced membrane blebbing and cell death in bovine aortic endothelial cells.
BMC physiology 2001;1():2.
2001: Mark Estacion; William G Sinkins; William Schilling
Regulation of Drosophila transient receptor potential-like (TrpL) channels by phospholipase C-dependent mechanisms.
The Journal of physiology 2001;530(Pt 1):1-19.
1999: William Schilling; William G Sinkins; Mark Estacion
Maitotoxin activates a nonselective cation channel and a P2Z/P2X(7)-like cytolytic pore in human skin fibroblasts.
The American journal of physiology 1999;277(4 Pt 1):C755-65.
1999: Mark Estacion; William G Sinkins; William Schilling
Stimulation of Drosophila TrpL by capacitative Ca2+ entry.
The Biochemical journal 1999;341 ( Pt 1)():41-9.
1998: William G Sinkins; Mark Estacion; William Schilling
Functional expression of TrpC1: a human homologue of the Drosophila Trp channel.
The Biochemical journal 1998;331 ( Pt 1)():331-9.
1997: Mark Estacion; L J Mordan
PDGF-stimulated calcium influx changes during in vitro cell transformation.
Cellular signalling 1997;9(5):363-6.
1997: H B Nguyen; Mark Estacion; J Jay Gargus
Mutations causing achondroplasia and thanatophoric dysplasia alter bFGF-induced calcium signals in human diploid fibroblasts.
Human molecular genetics 1997;6(5):681-8.
1996: Mark Estacion; H B Nguyen; J Jay Gargus
Calcium is permeable through a maitotoxin-activated nonselective cation channel in mouse L cells.
The American journal of physiology 1996;270(4 Pt 1):C1145-52.
1993: Z Wang; Mark Estacion; L J Mordan
Ca2+ influx via T-type channels modulates PDGF-induced replication of mouse fibroblasts.
The American journal of physiology 1993;265(5 Pt 1):C1239-46.
1993: Mark Estacion; L J Mordan
Competence induction by PDGF requires sustained calcium influx by a mechanism distinct from storage-dependent calcium influx.
Cell calcium 1993;14(6):439-54.
1993: Mark Estacion; L J Mordan
Expression of voltage-gated calcium channels correlates with PDGF-stimulated calcium influx and depends upon cell density in C3H 10T1/2 mouse fibroblasts.
Cell calcium 1993;14(2):161-71.
1991: Mark Estacion
Characterization of ion channels seen in subconfluent human dermal fibroblasts.
The Journal of physiology 1991;436():579-601.
1991: Mark Estacion
Acute electrophysiological responses of bradykinin-stimulated human fibroblasts.
The Journal of physiology 1991;436():603-20.
1990: Mark Estacion
Inhibition of voltage-dependent Na+ current in cell-fusion hybrids containing activated c-Ha-ras.
The Journal of membrane biology 1990;113(2):169-75.