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David Roodman

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Younghun Jung; Yusuke Shiozawa; Jingcheng Wang; Lalit R Patel; Aaron Havens; Junhui Song; Paul H Krebsbach; David G Roodman; Russell Taichman
Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche.
Frank C Cackowski; Judith L Anderson; Kenneth D Patrene; Rushir J Choksi; Steven D Shapiro; Jolene J Windle; Harry C Blair; David G Roodman
Osteoclasts are important for bone angiogenesis.
Rekha Pal; Martin Janz; Deborah L Galson; Margarete Gries; Shirong Li; Korinna Jöhrens; Ioannis Anagnostopoulos; Bernd Dörken; Markus Y Mapara; Lisa Borghesi; Lela Kardava; David G Roodman; Christine Milcarek; Suzanne Lentzsch
C/EBPbeta regulates transcription factors critical for proliferation and survival of multiple myeloma cells.

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2011: Younghun Jung; Yusuke Shiozawa; Jingcheng Wang; Lalit R Patel; Aaron Havens; Junhui Song; Paul H Krebsbach; David G Roodman; Russell Taichman
Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche.
Experimental hematology 2011;39(2):151-166.e1.
2010: Frank C Cackowski; Judith L Anderson; Kenneth D Patrene; Rushir J Choksi; Steven D Shapiro; Jolene J Windle; Harry C Blair; David G Roodman
Osteoclasts are important for bone angiogenesis.
Blood 2010;115(1):140-9.
2009: Rekha Pal; Martin Janz; Deborah L Galson; Margarete Gries; Shirong Li; Korinna Jöhrens; Ioannis Anagnostopoulos; Bernd Dörken; Markus Y Mapara; Lisa Borghesi; Lela Kardava; David G Roodman; Christine Milcarek; Suzanne Lentzsch
C/EBPbeta regulates transcription factors critical for proliferation and survival of multiple myeloma cells.
Blood 2009;114(18):3890-8.
2009: S J Choi; David G Roodman; J Q Feng; I S Song; K Amin; P S Hart; John Wright; N Haruyama; Thomas Hart
In vivo impact of a 4 bp deletion mutation in the DLX3 gene on bone development.
Developmental biology 2009;325(1):129-37.
2008: Yuko Hiruma; Noriyoshi Kurihara; Mark A Subler; Hua Zhou; Christina S Boykin; Heju Zhang; Seiichi Ishizuka; David W Dempster; David G Roodman; Jolene J Windle
A SQSTM1/p62 mutation linked to Paget's disease increases the osteoclastogenic potential of the bone microenvironment.
Human molecular genetics 2008;17(23):3708-19.
2008: David G Roodman
Novel targets for myeloma bone disease.
Expert opinion on therapeutic targets 2008;12(11):1377-87.
2008: Robert E Coleman; Theresa A Guise; Allan Lipton; David G Roodman; James R Berenson; Jean-Jacques Body; Brendan F Boyce; Laura M Calvi; Peyman Hadji; Eugene McCloskey; Fred Saad; Matthew R Smith; Larry J Suva; Russell S Taichman; Robert L Vessella; Katherine N Weilbaecher
Advancing treatment for metastatic bone cancer: consensus recommendations from the Second Cambridge Conference.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(20):6387-95.
2008: Yusuke Shiozawa; Aaron Havens; Younghun Jung; Anne M Ziegler; Elisabeth A Pedersen; Jianhua Wang; Jingcheng Wang; Ganwei Lu; David G Roodman; Robert D Loberg; Kenneth J Pienta; Russell Taichman
Annexin II/annexin II receptor axis regulates adhesion, migration, homing, and growth of prostate cancer.
Journal of cellular biochemistry 2008;105(2):370-80.
2008: Sanjai Sharma; Elizabeta Nemeth; Yi-Hsiang Chen; Julia Goodnough; Alissa Huston; David G Roodman; Tomas Ganz; Alan Lichtenstein
Involvement of hepcidin in the anemia of multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(11):3262-7.
2008: Seiichi Ishizuka; Noriyoshi Kurihara; Yuko Hiruma; Daishiro Miura; Jun-ichi Namekawa; Azusa Tamura; Yuko Kato-Nakamura; Yusuke Nakano; Kazuya Takenouchi; Yuichi Hashimoto; Kazuo Nagasawa; David G Roodman
1alpha,25-Dihydroxyvitamin D(3)-26,23-lactam analogues function as vitamin D receptor antagonists in human and rodent cells.
The Journal of steroid biochemistry and molecular biology 2008;110(3-5):269-77.
2008: David G Roodman
Bone building with bortezomib.
The Journal of clinical investigation 2008;118(2):462-4.
2008: David G Roodman; William C Dougall
RANK ligand as a therapeutic target for bone metastases and multiple myeloma.
Cancer treatment reviews 2008;34(1):92-101.
2008: David G Roodman
Skeletal imaging and management of bone disease.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2008;():313-9.
2007: Flavia R Esteve; David G Roodman
Pathophysiology of myeloma bone disease.
Best practice & research. Clinical haematology 2007;20(4):613-24.
2007: Suzanne Lentzsch; Lori A Ehrlich; David G Roodman
Pathophysiology of multiple myeloma bone disease.
Hematology/oncology clinics of North America 2007;21(6):1035-49, viii.
2007: David G Roodman
Treatment strategies for bone disease.
Bone marrow transplantation 2007;40(12):1139-46.
2007: Frank C Cackowski; David G Roodman
Perspective on the osteoclast: an angiogenic cell?
Annals of the New York Academy of Sciences 2007;1117():12-25.
2007: Suzanne Lentzsch; Gary Elliott; David G Roodman
SDX-308 and SDX-101, non-steroidal anti-inflammatory drugs, as therapeutic candidates for treating hematologic malignancies including myeloma.
Archiv der Pharmazie 2007;340(10):511-6.
2007: Yi Lu; Zhong Cai; Guozhi Xiao; Evan T Keller; Atsushi Mizokami; Zhi Yao; David G Roodman; Jian Zhang
Monocyte chemotactic protein-1 mediates prostate cancer-induced bone resorption.
Cancer research 2007;67(8):3646-53.
2007: Yazan Alsayed; Hai T Ngo; Judith M Runnels; Xavier Leleu; Ujjal K Singha; Costas M Pitsillides; Joel A Spencer; Teresa Kimlinger; Joanna M Ghobrial; Xiaoying Jia; Ganwei Lu; Michael Timm; Ashok Kumar; Daniel Côté; Israel Veilleux; Karen E Hedin; David G Roodman; Thomas E Witzig; Andrew L Kung; Teru Hideshima; Kenneth C Anderson; Charles P Lin; Irene M Ghobrial
Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma.
Blood 2007;109(7):2708-17.
2007: Rentian Feng; Gülsüm Anderson; Guozhi Xiao; Gary Elliott; Lorenzo Leoni; Markus Y Mapara; David G Roodman; Suzanne Lentzsch
SDX-308, a nonsteroidal anti-inflammatory agent, inhibits NF-kappaB activity, resulting in strong inhibition of osteoclast formation/activity and multiple myeloma cell growth.
Blood 2007;109(5):2130-8.
2007: Veronica Garcia-Palacios; Ho Yeon Chung; Sun Jin Choi; Aliye Sarmasik; Noriyoshi Kurihara; Jun Won Lee; Deborah L Galson; Robert Collins; David G Roodman
Eosinophil chemotactic factor-L (ECF-L) enhances osteoclast formation by increasing in osteoclast precursors expression of LFA-1 and ICAM-1.
Bone 2007;40(2):316-22.
2007: David G Roodman
Bone-breaking cancer treatment.
Nature medicine 2007;13(1):25-6.
2007: Noriyoshi Kurihara; Yuko Hiruma; Hua Zhou; Mark A Subler; David W Dempster; Frederick R Singer; Sakamuri V Reddy; Helen E Gruber; Jolene J Windle; David G Roodman
Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease.
The Journal of clinical investigation 2007;117(1):133-42.
2006: Nicola Giuliani; Vittorio Rizzoli; David G Roodman
Multiple myeloma bone disease: Pathophysiology of osteoblast inhibition.
Blood 2006;108(13):3992-6.
2006: Noriyoshi Kurihara; Hua Zhou; Sakamuri V Reddy; Veronica Garcia-Palacios; Mark A Subler; David W Dempster; Jolene J Windle; David G Roodman
Experimental models of Paget's disease.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21 Suppl 2():P55-7.
2006: Frederick R Singer; Barbara G Mills; Helen E Gruber; Jolene J Windle; David G Roodman
Ultrastructure of bone cells in Paget's disease of bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21 Suppl 2():P51-4.
2006: Alissa Huston; Jason Brown; David G Roodman
Tumor lysis syndrome following thalidomide and dexamethasone therapy for newly diagnosed multiple myeloma.
Experimental hematology 2006;34(12):1616.
2006: Lanie K Francis; Yazan Alsayed; Xavier Leleu; Xiaoying Jia; Ujjal K Singha; Judith Anderson; Michael Timm; Hai T Ngo; Ganwei Lu; Alissa Huston; Lori A Ehrlich; Elizabeth Dimmock; Suzanne Lentzsch; Teru Hideshima; David G Roodman; Kenneth C Anderson; Irene M Ghobrial
Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(22):6826-35.
2006: David G Roodman
New potential targets for treating myeloma bone disease.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(20 Pt 2):6270s-6273s.
2006: Allan Lipton; James R Berenson; Jean-Jacques Body; Brendan F Boyce; Oyvind S Bruland; Michael A Carducci; Charles S Cleeland; Denis R Clohisy; Robert E Coleman; Richard J Cook; Theresa A Guise; Roger N Pearse; Trevor J Powles; Michael J Rogers; David G Roodman; Matthew R Smith; Larry J Suva; Robert L Vessella; Katherine N Weilbaecher; Laura King
Advances in treating metastatic bone cancer: summary statement for the First Cambridge Conference.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(20 Pt 2):6209s-6212s.
2006: Ganwei Lu; Hidefumi Maeda; Sakamuri V Reddy; Noriyoshi Kurihara; Robin J Leach; Judith L Anderson; David G Roodman
Cloning and characterization of the annexin II receptor on human marrow stromal cells.
The Journal of biological chemistry 2006;281(41):30542-50.
2006: G Kesava Reddy; Tariq I Mughal; David G Roodman
Novel approaches in the management of myeloma-related skeletal complications.
Supportive cancer therapy 2006;4(1):15-8.
2006: Hongwei Rao; Ganwei Lu; Hiroshi Kajiya; Veronica Garcia-Palacios; Noriyoshi Kurihara; Judy Anderson; Ken Patrene; Dean Sheppard; Harry C Blair; Jolene J Windle; Sun Jin Choi; David G Roodman
Alpha9beta1: a novel osteoclast integrin that regulates osteoclast formation and function.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(10):1657-65.
2006: Rohit Aggarwal; Irene M Ghobrial; David G Roodman
Chemokines in multiple myeloma.
Experimental hematology 2006;34(10):1289-95.
2006: Aaron N Nguyen; Elizabeth G Stebbins; Margaret Henson; Gilbert O'Young; Sun J Choi; Diana Quon; Debby Damm; Mamatha Reddy; Jing Y Ma; Edwin Haghnazari; Ann M Kapoun; Satyanarayana Medicherla; Protter Andrew; George F Schreiner; Noriyoshi Kurihara; Judy Anderson; David G Roodman; Tony A Navas; Linda S Higgins
Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation.
Experimental cell research 2006;312(10):1909-23.
2006: Alissa Huston; David G Roodman
Role of the microenvironment in multiple myeloma bone disease.
Future oncology (London, England) 2006;2(3):371-8.
2006: Veronica Garcia-Palacios; Ho Yeon Chung; Sun Jin Choi; Noriyoshi Kurihara; Jun Won Lee; Lori A Ehrlich; Robert Collins; David G Roodman
Eosinophil chemotactic factor-L (ECF-L) enhances osteoclast formation by increasing ICAM-1 expression.
Annals of the New York Academy of Sciences 2006;1068():240-3.
2006: David G Roodman
Regulation of osteoclast differentiation.
Annals of the New York Academy of Sciences 2006;1068():100-9.
2006: Noriyoshi Kurihara; Hua Zhou; Sakamuri V Reddy; Veronica Garcia-Palacios; Mark A Subler; David W Dempster; Jolene J Windle; David G Roodman
Expression of measles virus nucleocapsid protein in osteoclasts induces Paget's disease-like bone lesions in mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(3):446-55.
2005: Lori A Ehrlich; David G Roodman
The role of immune cells and inflammatory cytokines in Paget's disease and multiple myeloma.
Immunological reviews 2005;208():252-66.
2005: Lori A Ehrlich; Ho Yeon Chung; Irene M Ghobrial; Sun Jin Choi; Francesca Morandi; Simona Colla; Vittorio Rizzoli; David G Roodman; Nicola Giuliani
IL-3 is a potential inhibitor of osteoblast differentiation in multiple myeloma.
Blood 2005;106(4):1407-14.
2005: David G Roodman
High bone turnover markers predict poor outcome in patients with bone metastasis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(22):4821-2.
2005: David G Roodman
Myeloma bone disease: pathogenesis and treatment.
Oncology (Williston Park, N.Y.) 2005;19(8):983-4, 986.
2005: Fanghong Li; Hoyeon Chung; Sakamuri V Reddy; Ganwei Lu; Noriyoshi Kurihara; Allan Z Zhao; David G Roodman
Annexin II stimulates RANKL expression through MAPK.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(7):1161-7.
2005: Seiichi Ishizuka; Noriyoshi Kurihara; Sakamuri V Reddy; Jillian Cornish; Tim Cundy; David G Roodman
(23S)-25-Dehydro-1{alpha}-hydroxyvitamin D3-26,23-lactone, a vitamin D receptor antagonist that inhibits osteoclast formation and bone resorption in bone marrow cultures from patients with Paget's disease.
Endocrinology 2005;146(4):2023-30.
2005: Raghavendra Vasudeva Murthy; Gunnar Arbman; Jingfang Gao; David G Roodman; Xiao-Feng Sun
Legumain expression in relation to clinicopathologic and biological variables in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(6):2293-9.
2005: Yasuo Oba; Jun Won Lee; Lori A Ehrlich; Ho Yeon Chung; Diane F Jelinek; Natalie S Callander; Richard Horuk; Sun Jin Choi; David G Roodman
MIP-1alpha utilizes both CCR1 and CCR5 to induce osteoclast formation and increase adhesion of myeloma cells to marrow stromal cells.
Experimental hematology 2005;33(3):272-8.
2005: David G Roodman; Jolene J Windle
Paget disease of bone.
The Journal of clinical investigation 2005;115(2):200-8.
2004: Noriyoshi Kurihara; Sakamuri V Reddy; Norie Araki; Seiichi Ishizuka; Keiichi Ozono; Jillian Cornish; Tim Cundy; Frederick R Singer; David G Roodman
Role of TAFII-17, a VDR binding protein, in the increased osteoclast formation in Paget's Disease.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(7):1154-64.
2004: Seiichi Ishizuka; Noriyoshi Kurihara; Daishiro Miura; Kazuya Takenouchi; Jillian Cornish; Tim Cundy; Sakamuri V Reddy; David G Roodman
Vitamin D antagonist, TEI-9647, inhibits osteoclast formation induced by 1alpha,25-dihydroxyvitamin D3 from pagetic bone marrow cells.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):331-4.
2004: Noriyoshi Kurihara; Seiichi Ishizuka; Anne Demulder; Cheikh Menaa; David G Roodman
Paget's disease-a VDR coactivator disease?
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):321-5.
2004: David G Roodman
Mechanisms of bone metastasis.
The New England journal of medicine 2004;350(16):1655-64.
2004: Jun Won Lee; Ho Yeon Chung; Lori A Ehrlich; Diane F Jelinek; Natalie S Callander; David G Roodman; Sun Jin Choi
IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cells.
Blood 2004;103(6):2308-15.
2004: Jennifer L Roccisana; Noriaki Kawanabe; Hiroshi Kajiya; Masanori Koide; David G Roodman; Sakamuri V Reddy
Functional role for heat shock factors in the transcriptional regulation of human RANK ligand gene expression in stromal/osteoblast cells.
The Journal of biological chemistry 2004;279(11):10500-7.
2004: David G Roodman
Pathogenesis of myeloma bone disease.
Blood cells, molecules & diseases 2004;32(2):290-2.
2004: David G Roodman; Sun Jin Choi
MIP-1 alpha and myeloma bone disease.
Cancer treatment and research 2004;118():83-100.
2003: David G Roodman
Mechanisms of bone resorption in myeloma.
Journal of musculoskeletal & neuronal interactions 2003;3(4):271-2; discussion 292-4.
2003: Yasuo Oba; Ho Yeon Chung; Sun Jin Choi; David G Roodman
Eosinophil chemotactic factor-L (ECF-L): a novel osteoclast stimulating factor.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(7):1332-41.
2003: Sun J Choi; Tomoko Oba; Natalie S Callander; Diane F Jelinek; David G Roodman
AML-1A and AML-1B regulation of MIP-1alpha expression in multiple myeloma.
Blood 2003;101(10):3778-83.
2002: David G Roodman
Role of the bone marrow microenvironment in multiple myeloma.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(11):1921-5.
2002: Christian Darimont; Ornella Avanti; Yvonne Tromvoukis; Patricia Vautravers-Leone; Nori Kurihara; David G Roodman; Lorel M Colgin; Heide Tullberg-Reinert; Andrea M A Pfeifer; Elizabeth A Offord; Katherine Mace
SV40 T antigen and telomerase are required to obtain immortalized human adult bone cells without loss of the differentiated phenotype.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2002;13(2):59-67.
2002: Kenneth C Anderson; John D Shaughnessy; Bart Barlogie; Jean-Luc Harousseau; David G Roodman
Multiple myeloma.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2002;():214-40.
2002: William E Friedrichs; Sakamuri V Reddy; Jan M Bruder; Tim Cundy; Jillian Cornish; Frederick R Singer; David G Roodman
Sequence analysis of measles virus nucleocapsid transcripts in patients with Paget's disease.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(1):145-51.
2001: SJ Choi; Y Oba; Yair Gazitt; M Alsina; J Cruz; J Anderson; David G Roodman
Antisense inhibition of macrophage inflammatory protein 1-alpha blocks bone destruction in a model of myeloma bone disease.
The Journal of clinical investigation 2001;108(12):1833-41.
2001: SJ Choi; Noriyoshi Kurihara; Y Oba; David G Roodman
Osteoclast inhibitory peptide 2 inhibits osteoclast formation via its C-terminal fragment.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(10):1804-11.
2001: David G Roodman
Studies in Paget's disease and their relevance to oncology.
Seminars in oncology 2001;28(4 Suppl 11):15-21.
2001: David G Roodman
Biology of osteoclast activation in cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(15):3562-71.
2001: Natalie S Callander; David G Roodman
Myeloma bone disease.
Seminars in hematology 2001;38(3):276-85.
2001: Madhav V Dhodapkar; Joth L Jacobson; Morie A Gertz; S E Rivkin; David G Roodman; Joseph M Tuscano; M Shurafa; R A Kyle; John J Crowley; Bart Barlogie
Prognostic factors and response to fludarabine therapy in patients with Waldenström macroglobulinemia: results of United States intergroup trial (Southwest Oncology Group S9003).
Blood 2001;98(1):41-8.
2001: Sakamuri V Reddy; Noriyoshi Kurihara; Cheikh Menaa; Gary Landucci; Donald N Forthal; BA Koop; Jolene J Windle; David G Roodman
Osteoclasts formed by measles virus-infected osteoclast precursors from hCD46 transgenic mice express characteristics of pagetic osteoclasts.
Endocrinology 2001;142(7):2898-905.
2001: J H Han; SJ Choi; Noriyoshi Kurihara; M Koide; Y Oba; David G Roodman
Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand.
Blood 2001;97(11):3349-53.
2001: SJ Choi; J H Han; David G Roodman
ADAM8: a novel osteoclast stimulating factor.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(5):814-22.
2001: Sakamuri V Reddy; Noriyoshi Kurihara; Cheikh Menaa; David G Roodman
Paget's disease of bone: a disease of the osteoclast.
Reviews in endocrine & metabolic disorders 2001;2(2):195-201.
2001: J C Cruz; M Alsina; F Craig; Toshiyuki Yoneda; J L Anderson; Mari Hashitate Dallas; David G Roodman
Ibandronate decreases bone disease development and osteoclast stimulatory activity in an in vivo model of human myeloma.
Experimental hematology 2001;29(4):441-7.
2001: Robin J Leach; Frederick R Singer; David G Roodman
The genetics of Paget's disease of the bone.
The Journal of clinical endocrinology and metabolism 2001;86(1):24-8.
2000: Michael P Whyte; B G Mills; William R Reinus; Michelle N Podgornik; David G Roodman; Francis H Gannon; MC Eddy; William H McAlister
Expansile skeletal hyperphosphatasia: a new familial metabolic bone disease.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(12):2330-44.
2000: SJ Choi; J C Cruz; F Craig; H Chung; RD Devlin; David G Roodman; M Alsina
Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma.
Blood 2000;96(2):671-5.
2000: Cheikh Menaa; Sakamuri V Reddy; Noriyoshi Kurihara; H Maeda; D Anderson; Tim Cundy; Jillian Cornish; Frederick R Singer; Jan M Bruder; David G Roodman
Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget's disease of bone.
The Journal of clinical investigation 2000;105(12):1833-8.
2000: S Y Rha; Elzbieta Izbicka; R Lawrence; K Davidson; D Sun; Mary Pat Moyer; David G Roodman; Laurence H Hurley; Daniel Von Hoff
Effect of telomere and telomerase interactive agents on human tumor and normal cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):987-93.
2000: Noriyoshi Kurihara; Sakamuri V Reddy; Cheikh Menaa; D Anderson; David G Roodman
Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype.
The Journal of clinical investigation 2000;105(5):607-14.
2000: Cheikh Menaa; J Barsony; Sakamuri V Reddy; Jillian Cornish; Tim Cundy; David G Roodman
1,25-Dihydroxyvitamin D3 hypersensitivity of osteoclast precursors from patients with Paget's disease.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(2):228-36.
2000: Teuvo A Hentunen; S J Choi; B F Boyce; Mark Dallas; Sarah L Dallas; G L Shen-Ong; David G Roodman
A murine model of inflammatory bone disease.
Bone 2000;26(2):183-8.
2000: Cheikh Menaa; Noriyoshi Kurihara; David G Roodman
CFU-GM-derived cells form osteoclasts at a very high efficiency.
Biochemical and biophysical research communications 2000;267(3):943-6.
2000: R Schaub; BR DuPont; David G Roodman; Robin J Leach; Sakamuri V Reddy
Assignment of OSTF1 to human chromosome bands 12q24.1-->q24.2 by in situ hybridization.
Cytogenetics and cell genetics 2000;88(1-2):87-8.
1999: Sakamuri V Reddy; Cheikh Menaa; Frederick R Singer; Tim Cundy; Jillian Cornish; M P Whyte; David G Roodman
Measles virus nucleocapsid transcript expression is not restricted to the osteoclast lineage in patients with Paget's disease of bone.
Experimental hematology 1999;27(10):1528-32.
1999: Robin J Leach; Frederick R Singer; Jannine Cody; David G Roodman
Variable disease severity associated with a Paget's disease predisposition gene.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14 Suppl 2():17-20.
1999: Sakamuri V Reddy; Cheikh Menaa; Frederick R Singer; Anne Demulder; David G Roodman
Cell biology of Paget's disease.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14 Suppl 2():3-8.
1999: SJ Choi; Sakamuri V Reddy; RD Devlin; Cheikh Menaa; H Chung; B F Boyce; David G Roodman
Identification of human asparaginyl endopeptidase (legumain) as an inhibitor of osteoclast formation and bone resorption.
The Journal of biological chemistry 1999;274(39):27747-53.
1999: Jussi M Halleen; Seija R Räisänen; J J Salo; Sakamuri V Reddy; David G Roodman; Teuvo A Hentunen; Petri Lehenkari; Helena Kaija; Pirkko Vihko; H Kalervo Väänänen
Intracellular fragmentation of bone resorption products by reactive oxygen species generated by osteoclastic tartrate-resistant acid phosphatase.
The Journal of biological chemistry 1999;274(33):22907-10.
1999: David G Roodman
Cell biology of the osteoclast.
Experimental hematology 1999;27(8):1229-41.
1999: Teuvo A Hentunen; S H Jackson; H Chung; Sakamuri V Reddy; J Lorenzo; S J Choi; David G Roodman
Characterization of immortalized osteoclast precursors developed from mice transgenic for both bcl-X(L) and simian virus 40 large T antigen.
Endocrinology 1999;140(7):2954-61.
1999: Cheikh Menaa; RD Devlin; Sakamuri V Reddy; Yair Gazitt; SJ Choi; David G Roodman
Annexin II increases osteoclast formation by stimulating the proliferation of osteoclast precursors in human marrow cultures.
The Journal of clinical investigation 1999;103(11):1605-13.
1999: David G Roodman
Mechanisms of abnormal bone turnover in Paget's disease.
Bone 1999;24(5 Suppl):39S-40S.
1998: Sakamuri V Reddy; R Devlin; Cheikh Menaa; R Nishimura; S J Choi; Mark Dallas; Toshiyuki Yoneda; David G Roodman
Isolation and characterization of a cDNA clone encoding a novel peptide (OSF) that enhances osteoclast formation and bone resorption.
Journal of cellular physiology 1998;177(4):636-45.
1998: SJ Choi; RD Devlin; Cheikh Menaa; H Chung; David G Roodman; Sakamuri V Reddy
Cloning and identification of human Sca as a novel inhibitor of osteoclast formation and bone resorption.
The Journal of clinical investigation 1998;102(7):1360-8.
1998: Shou-Jiang Gao; M Alsina; Jian-Hong Deng; C R Harrison; EA Montalvo; Charles T Leach; David G Roodman; Hal B Jenson
Antibodies to Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in patients with multiple myeloma.
The Journal of infectious diseases 1998;178(3):846-9.
1998: Maggie J Nellissery; Susan Padalecki; Z Brkanac; Frederick R Singer; David G Roodman; K K Unni; Robin J Leach; Marc F Hansen
Evidence for a novel osteosarcoma tumor-suppressor gene in the chromosome 18 region genetically linked with Paget disease of bone.
American journal of human genetics 1998;63(3):817-24.
1998: Teuvo A Hentunen; Sakamuri V Reddy; B F Boyce; R Devlin; H R Park; H Chung; Katri S Selander; Mark Dallas; Noriyoshi Kurihara; Deborah L Galson; Steven R Goldring; BA Koop; Jolene J Windle; David G Roodman
Immortalization of osteoclast precursors by targeting Bcl -XL and Simian virus 40 large T antigen to the osteoclast lineage in transgenic mice.
The Journal of clinical investigation 1998;102(1):88-97.
1998: David G Roodman; Y Ohsaki; M M Miller; Anne Demulder; David Hosking; Frederick R Singer; Linda McManus
Pagetic osteoclasts formed in vitro: absence of paracrystalline inclusions.
Journal of submicroscopic cytology and pathology 1998;30(2):315-27.
1998: RD Devlin; Sakamuri V Reddy; Rocco Savino; G Ciliberto; David G Roodman
IL-6 mediates the effects of IL-1 or TNF, but not PTHrP or 1,25(OH)2D3, on osteoclast-like cell formation in normal human bone marrow cultures.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(3):393-9.
1998: J Roach; S J Choi; R L Schaub; Robin J Leach; David G Roodman; Sakamuri V Reddy
Further characterization of the murine collagenase (type IVB) gene promoter and analysis of mRNA expression in murine tissues.
Gene 1998;208(2):117-22.
1998: David G Roodman
Osteoclast differentiation and activity.
Biochemical Society transactions 1998;26(1):7-13.
1998: Sakamuri V Reddy; David G Roodman
Control of osteoclast differentiation.
Critical reviews in eukaryotic gene expression 1998;8(1):1-17.
1998: Deepali Sachdev; Y Ohsaki; David G Roodman; John M Chirgwin
Epitope mapping of recombinant human procathepsin D.
Advances in experimental medicine and biology 1998;436():185-9.
1997: Jannine Cody; Frederick R Singer; David G Roodman; B Otterund; T B Lewis; Mark Leppert; Robin J Leach
Genetic linkage of Paget disease of the bone to chromosome 18q.
American journal of human genetics 1997;61(5):1117-22.
1997: David G Roodman
Mechanisms of bone lesions in multiple myeloma and lymphoma.
Cancer 1997;80(8 Suppl):1557-63.
1997: H L Uy; Gregory R Mundy; BF Boyce; Beryl Story; C R Dunstan; Juan Juan Yin; David G Roodman; Theresa A Guise
Tumor necrosis factor enhances parathyroid hormone-related protein-induced hypercalcemia and bone resorption without inhibiting bone formation in vivo.
Cancer research 1997;57(15):3194-9.
1997: TW Tsai; L A Hammond; M Rinaldi; K Martin; F Tio; J Maples; Cesar O Freytes; David G Roodman
Cokeromyces recurvatus infection in a bone marrow transplant recipient.
Bone marrow transplantation 1997;19(3):301-2.
1996: Sakamuri V Reddy; Frederick R Singer; L Mallette; David G Roodman
Detection of measles virus nucleocapsid transcripts in circulating blood cells from patients with Paget disease.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(11):1602-7.
1996: Sakamuri V Reddy; O Alcantara; David G Roodman; David H Boldt
Inhibition of tartrate-resistant acid phosphatase gene expression by hemin and protoporphyrin IX. Identification of a hemin-responsive inhibitor of transcription.
Blood 1996;88(6):2288-97.
1996: David G Roodman
Paget's disease and osteoclast biology.
Bone 1996;19(3):209-12.
1996: David G Roodman
Advances in bone biology: the osteoclast.
Endocrine reviews 1996;17(4):308-32.
1996: M P Whyte; R Leelawattana; Sakamuri V Reddy; David G Roodman
Absence of paramyxo virus transcripts in juvenile Paget bone disease.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(7):1041.
1996: R D Devlin; H G Bone; David G Roodman
Interleukin-6: a potential mediator of the massive osteolysis in patients with Gorham-Stout disease.
The Journal of clinical endocrinology and metabolism 1996;81(5):1893-7.
1996: M Alsina; B Boyce; R D Devlin; J L Anderson; F Craig; Gregory R Mundy; David G Roodman
Development of an in vivo model of human multiple myeloma bone disease.
Blood 1996;87(4):1495-501.
1996: A Michael Parfitt; G R Mundy; David G Roodman; David Hughes; B F Boyce
A new model for the regulation of bone resorption, with particular reference to the effects of bisphosphonates.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(2):150-9.
1996: M Alsina; Theresa A Guise; David G Roodman
Cytokine regulation of bone cell differentiation.
Vitamins and hormones 1996;52():63-98.
1996: BR DuPont; R Linn; Cara Gonzales; David G Roodman; A Y Sakaguchi; P A Lalley; R E Fournier; Robin J Leach
Assignment of matrix metalloproteinase 9 (Mmp9) to mouse chromosome 2 bands H1-H2.
Cytogenetics and cell genetics 1996;74(1-2):118-9.
1995: B F Boyce; K Wright; Sakamuri V Reddy; BA Koop; Beryl Story; R Devlin; Robin J Leach; David G Roodman; Jolene J Windle
Targeting simian virus 40 T antigen to the osteoclast in transgenic mice causes osteoclast tumors and transformation and apoptosis of osteoclasts.
Endocrinology 1995;136(12):5751-9.
1995: David Hughes; Kenneth Wright; H L Uy; Akira Sasaki; Toshiyuki Yoneda; David G Roodman; Gregory R Mundy; B F Boyce
Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(10):1478-87.
1995: David G Roodman
Osteoclast function in Paget's disease and multiple myeloma.
Bone 1995;17(2 Suppl):57S-61S.
1995: M Alsina; B F Boyce; Gregory R Mundy; David G Roodman
An in vivo model of human multiple myeloma bone disease.
Stem cells (Dayton, Ohio) 1995;13 Suppl 2():48-50.
1995: H L Uy; Theresa A Guise; J De La Mata; S D Taylor; Beryl Story; Mark Dallas; B F Boyce; Gregory R Mundy; David G Roodman
Effects of parathyroid hormone (PTH)-related protein and PTH on osteoclasts and osteoclast precursors in vivo.
Endocrinology 1995;136(8):3207-12.
1995: M Bartkiewicz; N Hernando; Sakamuri V Reddy; David G Roodman; Roland Baron
Characterization of the osteoclast vacuolar H(+)-ATPase B-subunit.
Gene 1995;160(2):157-64.
1995: Sakamuri V Reddy; Frederick R Singer; David G Roodman
Bone marrow mononuclear cells from patients with Paget's disease contain measles virus nucleocapsid messenger ribonucleic acid that has mutations in a specific region of the sequence.
The Journal of clinical endocrinology and metabolism 1995;80(7):2108-11.
1995: J de la Mata; H L Uy; Theresa A Guise; Beryl Story; B F Boyce; Gregory R Mundy; David G Roodman
Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivo.
The Journal of clinical investigation 1995;95(6):2846-52.
1995: Sakamuri V Reddy; N Kuzhandaivelu; L G Acosta; David G Roodman
Characterization of the 5'-flanking region of the human tartrate-resistant acid phosphatase (TRAP) gene.
Bone 1995;16(5):587-93.
1995: Sakamuri V Reddy; JE Hundley; Jolene J Windle; O Alcantara; R Linn; Robin J Leach; David H Boldt; David G Roodman
Characterization of the mouse tartrate-resistant acid phosphatase (TRAP) gene promoter.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(4):601-6.
1995: S Takahashi; Sakamuri V Reddy; Mark Dallas; R Devlin; J Y Chou; David G Roodman
Development and characterization of a human marrow stromal cell line that enhances osteoclast-like cell formation.
Endocrinology 1995;136(4):1441-9.
1995: H L Uy; Mark Dallas; J W Calland; B F Boyce; Gregory R Mundy; David G Roodman
Use of an in vivo model to determine the effects of interleukin-1 on cells at different stages in the osteoclast lineage.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(2):295-301.
1995: S Takahashi; S Goldring; M Katz; S Hilsenbeck; R Williams; David G Roodman
Downregulation of calcitonin receptor mRNA expression by calcitonin during human osteoclast-like cell differentiation.
The Journal of clinical investigation 1995;95(1):167-71.
1995: David G Roodman
Application of bone marrow cultures to the study of osteoclast formation and osteoclast precursors in man.
Calcified tissue international 1995;56 Suppl 1():S22-3.
1994: S Takahashi; Sakamuri V Reddy; John M Chirgwin; R Devlin; C Haipek; J Anderson; David G Roodman
Cloning and identification of annexin II as an autocrine/paracrine factor that increases osteoclast formation and bone resorption.
The Journal of biological chemistry 1994;269(46):28696-701.
1994: Douglas Adkins; D Salzman; D Boldt; John Kuhn; R Irvin; David G Roodman; R Lyons; L Smith; Cesar O Freytes; Charles F LeMaistre
Phase I trial of dacarbazine with cyclophosphamide, carmustine, etoposide, and autologous stem-cell transplantation in patients with lymphoma and multiple myeloma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(9):1890-901.
1994: Barbara G Mills; A Frausto; Frederick R Singer; Y Ohsaki; Anne Demulder; David G Roodman
Multinucleated cells formed in vitro from Paget's bone marrow express viral antigens.
Bone 1994;15(4):443-8.
1994: Sakamuri V Reddy; S Takahashi; Mark Dallas; R E Williams; L Neckers; David G Roodman
Interleukin-6 antisense deoxyoligonucleotides inhibit bone resorption by giant cells from human giant cell tumors of bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(5):753-7.
1994: O Alcantara; Sakamuri V Reddy; David G Roodman; David H Boldt
Transcriptional regulation of the tartrate-resistant acid phosphatase (TRAP) gene by iron.
The Biochemical journal 1994;298 ( Pt 2)():421-5.
1994: David G Roodman
Biology of the osteoclast in Paget's disease.
Seminars in arthritis and rheumatism 1994;23(4):235-6.
1993: Thomas C Hardin; J M Koeller; John Kuhn; David G Roodman; Daniel Von Hoff
Nutritional parameters observed during 28-day infusion of recombinant human tumor necrosis factor-alpha.
JPEN. Journal of parenteral and enteral nutrition 1993;17(6):541-5.
1993: Anne Demulder; S Takahashi; Frederick R Singer; D J Hosking; David G Roodman
Abnormalities in osteoclast precursors and marrow accessory cells in Paget's disease.
Endocrinology 1993;133(5):1978-82.
1993: Sakamuri V Reddy; T Scarcez; Jolene J Windle; Robin J Leach; JE Hundley; John M Chirgwin; J Y Chou; David G Roodman
Cloning and characterization of the 5'-flanking region of the mouse tartrate-resistant acid phosphatase gene.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(10):1263-70.
1993: Sakamuri V Reddy; S Takahashi; C Haipek; John M Chirgwin; David G Roodman
Tartrate-resistant acid phosphatase gene expression as a facile reporter gene for screening transfection efficiency in mammalian cell cultures.
BioTechniques 1993;15(3):444-7.
1993: W E Gallwitz; Gregory R Mundy; C H Lee; M Qiao; David G Roodman; M Raftery; S J Gaskell; Lynda F Bonewald
5-Lipoxygenase metabolites of arachidonic acid stimulate isolated osteoclasts to resorb calcified matrices.
The Journal of biological chemistry 1993;268(14):10087-94.
1993: Douglas Adkins; R Irvin; John Kuhn; D H Boldt; David G Roodman; D Salzman; Cesar O Freytes; Daniel Von Hoff; Charles F LeMaistre
A phase I clinical and pharmacological profile of dacarbazine with autologous bone marrow transplantation in patients with solid tumors.
Investigational new drugs 1993;11(2-3):169-79.
1993: R Grimes; Sakamuri V Reddy; Robin J Leach; T Scarcez; David G Roodman; A Y Sakaguchi; P A Lalley; Jolene J Windle
Assignment of the mouse tartrate-resistant acid phosphatase gene (Acp5) to chromosome 9.
Genomics 1993;15(2):421-2.
1993: John R Eckardt; David G Roodman; D H Boldt; G M Clark; R Alvarez; C Page; H Gaskill; Charles F LeMaistre
Comparison of engraftment and acute GVHD in patients undergoing cryopreserved or fresh allogeneic BMT.
Bone marrow transplantation 1993;11(2):125-31.
1993: M V Marshall; M H Marshall; D R Degen; David G Roodman; John Kuhn; M E Ross; Daniel Von Hoff
In vitro cytotoxicity of hepsulfam against human tumor cell lines and primary human tumor colony forming units.
Stem cells (Dayton, Ohio) 1993;11(1):62-9.
1993: David G Roodman
Role of cytokines in the regulation of bone resorption.
Calcified tissue international 1993;53 Suppl 1():S94-8.
1992: Y Ohsaki; S Takahashi; T Scarcez; Anne Demulder; T Nishihara; R Williams; David G Roodman
Evidence for an autocrine/paracrine role for interleukin-6 in bone resorption by giant cells from giant cell tumors of bone.
Endocrinology 1992;131(5):2229-34.
1992: Anne Demulder; S V Suggs; Krisztina Maria Zsebo; T Scarcez; David G Roodman
Effects of stem cell factor on osteoclast-like cell formation in long-term human marrow cultures.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1992;7(11):1337-44.
1992: David G Roodman
Interleukin-6: an osteotropic factor?
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1992;7(5):475-8.
1992: David G Roodman; N Kurihara; Y Ohsaki; A Kukita; D Hosking; Anne Demulder; J F Smith; Frederick R Singer
Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of bone.
The Journal of clinical investigation 1992;89(1):46-52.
1992: Gregory R Mundy; David G Roodman; Lynda F Bonewald; Toshiyuki Yoneda; M Sabatini
Effects of TNF and lymphotoxin on bone cells.
Immunology series 1992;56():483-98.
1991: N Kurihara; Curt I Civin; David G Roodman
Osteotropic factor responsiveness of highly purified populations of early and late precursors for human multinucleated cells expressing the osteoclast phenotype.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991;6(3):257-61.
1991: David G Roodman
Osteoclast differentiation.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 1991;2(3):389-409.
1991: Gregory R Mundy; David G Roodman; Lynda F Bonewald; R O Oreffo; B F Boyce
Assays for bone resorption and bone formation.
Methods in enzymology 1991;198():502-10.
1991: David G Roodman; Thomas Kuehl; John VandeBerg; D Y Muirhead
In utero bone marrow transplantation of fetal baboons with mismatched adult baboon marrow.
Blood cells 1991;17(2):367-75.
1991: M C Sunderland; David G Roodman
Interleukin-3. Its biology and potential uses in pediatric hematology/oncology.
The American journal of pediatric hematology/oncology 1991;13(4):414-25.
1990: N Kurihara; S Gluck; David G Roodman
Sequential expression of phenotype markers for osteoclasts during differentiation of precursors for multinucleated cells formed in long-term human marrow cultures.
Endocrinology 1990;127(6):3215-21.
1990: D Y Muirhead; Thomas Kuehl; John VandeBerg; E M Menchaca; M P Downs; David G Roodman
Mixed lymphocyte culture reactivity of fetal baboons: application for in utero bone marrow transplantation.
Bone marrow transplantation 1990;6(4):263-7.
1990: N Kurihara; David G Roodman
Interferons-alpha and -gamma inhibit interleukin-1 beta-stimulated osteoclast-like cell formation in long-term human marrow cultures.
Journal of interferon research 1990;10(5):541-7.
1990: C Chenu; N Kurihara; G R Mundy; David G Roodman
Prostaglandin E2 inhibits formation of osteoclastlike cells in long-term human marrow cultures but is not a mediator of the inhibitory effects of transforming growth factor beta.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(7):677-81.
1990: N Kurihara; D Bertolini; T Suda; Y Akiyama; David G Roodman
IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(11):4226-30.
1990: U Clibon; L Bonewald; J Caro; David G Roodman
Erythropoietin fails to reverse the anemia in mice continuously exposed to tumor necrosis factor-alpha in vivo.
Experimental hematology 1990;18(5):438-41.
1990: N Kurihara; C Chenu; M Miller; Curt I Civin; David G Roodman
Identification of committed mononuclear precursors for osteoclast-like cells formed in long term human marrow cultures.
Endocrinology 1990;126(5):2733-41.
1990: A Kukita; L Bonewald; D Rosen; S Seyedin; Gregory R Mundy; David G Roodman
Osteoinductive factor inhibits formation of human osteoclast-like cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(8):3023-6.
1990: A Kukita; C Chenu; Linda McManus; G R Mundy; David G Roodman
Atypical multinucleated cells form in long-term marrow cultures from patients with Paget's disease.
The Journal of clinical investigation 1990;85(4):1280-6.
1989: X F Li; J Anderson; D Hutzler; David G Roodman
Hemin-induced erythroid differentiation changes the sensitivity of K562 cells to tumor necrosis factor-alpha.
Experimental hematology 1989;17(11):1059-62.
1989: R A Johnson; David G Roodman
Hematologic manifestations of malignancy.
Disease-a-month : DM 1989;35(11):721-68.
1989: T Kukita; David G Roodman
Development of a monoclonal antibody to osteoclasts formed in vitro which recognizes mononuclear osteoclast precursors in the marrow.
Endocrinology 1989;125(2):630-7.
1989: R A Johnson; T A Waddelow; J Caro; A Oliff; David G Roodman
Chronic exposure to tumor necrosis factor in vivo preferentially inhibits erythropoiesis in nude mice.
Blood 1989;74(1):130-8.
1989: D M Williams; L F Bonewald; David G Roodman; Gerald Byrne; D M Magee; J Schachter
Tumor necrosis factor alpha is a cytotoxin induced by murine Chlamydia trachomatis infection.
Infection and immunity 1989;57(5):1351-5.
1989: T Kukita; Linda McManus; M Miller; Curt I Civin; David G Roodman
Osteoclast-like cells formed in long-term human bone marrow cultures express a similar surface phenotype as authentic osteoclasts.
Laboratory investigation; a journal of technical methods and pathology 1989;60(4):532-8.
1989: R A Johnson; B F Boyce; G R Mundy; David G Roodman
Tumors producing human tumor necrosis factor induced hypercalcemia and osteoclastic bone resorption in nude mice.
Endocrinology 1989;124(3):1424-7.
1989: J Pfeilschifter; C Chenu; A Bird; Gregory R Mundy; David G Roodman
Interleukin-1 and tumor necrosis factor stimulate the formation of human osteoclastlike cells in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1989;4(1):113-8.
1989: N Takahashi; T Kukita; B R MacDonald; A Bird; G R Mundy; Linda McManus; M Miller; A Boyde; S J Jones; David G Roodman
Osteoclast-like cells form in long-term human bone marrow but not in peripheral blood cultures.
The Journal of clinical investigation 1989;83(2):543-50.
1989: David G Roodman; R A Johnson; U Clibon
Tumor necrosis factor alpha and the anemia of chronic disease: effects of chronic exposure to TNF on erythropoiesis in vivo.
Advances in experimental medicine and biology 1989;271():185-96.
1988: C Chenu; J Pfeilschifter; Gregory R Mundy; David G Roodman
Transforming growth factor beta inhibits formation of osteoclast-like cells in long-term human marrow cultures.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(15):5683-7.
1988: Naoyuki Takahashi; H Yamana; S Yoshiki; David G Roodman; G R Mundy; S J Jones; A Boyde; Toshio Suda
Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures.
Endocrinology 1988;122(4):1373-82.
1988: David G Roodman; John VandeBerg; Thomas Kuehl
In utero bone marrow transplantation of fetal baboons with mismatched adult marrow: initial observations.
Bone marrow transplantation 1988;3(2):141-7.
1987: David G Roodman; A Bird; D Hutzler; W Montgomery
Tumor necrosis factor-alpha and hematopoietic progenitors: effects of tumor necrosis factor on the growth of erythroid progenitors CFU-E and BFU-E and the hematopoietic cell lines K562, HL60, and HEL cells.
Experimental hematology 1987;15(9):928-35.
1987: F H Gardner; J B Alperin; J A Belli; P C Farley; E P Frenkel; J R Redman; David G Roodman; D A Sears; A A Trowbridge
Hematology-oncology. Hematology-Oncology Workgroup, Legislative Task Force on Cancer in Texas.
Texas medicine 1987;83(9 Pt 2):59-71.
1987: N Takahashi; G R Mundy; Thomas Kuehl; David G Roodman
Osteoclast-like cell formation in fetal and newborn long-term baboon marrow cultures is more sensitive to 1,25-dihydroxyvitamin D3 than adult long-term marrow cultures.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1987;2(4):311-7.
1987: David G Roodman; C F LeMaistre; G M Clark; C P Page; T F Newcomb; W A Knight
CFU-GEMM correlate with neutrophil and platelet recovery in patients receiving autologous marrow transplantation after high-dose melphalan chemotherapy.
Bone marrow transplantation 1987;2(2):165-73.
1987: B R MacDonald; N Takahashi; Linda McManus; J Holahan; G R Mundy; David G Roodman
Formation of multinucleated cells that respond to osteotropic hormones in long term human bone marrow cultures.
Endocrinology 1987;120(6):2326-33.
1987: John C Lee; Thomas Kuehl; David G Roodman
Developmental changes in membrane proteins from baboon erythrocytes.
Comparative biochemistry and physiology. B, Comparative biochemistry 1987;88(1):223-6.
1987: David G Roodman
Mechanisms of erythroid suppression in the anemia of chronic disease.
Blood cells 1987;13(1-2):171-84.
1986: N Takahashi; G R Mundy; David G Roodman
Recombinant human interferon-gamma inhibits formation of human osteoclast-like cells.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(11):3544-9.
1986: N Takahashi; B R MacDonald; J Hon; M E Winkler; R Derynck; G R Mundy; David G Roodman
Recombinant human transforming growth factor-alpha stimulates the formation of osteoclast-like cells in long-term human marrow cultures.
The Journal of clinical investigation 1986;78(4):894-8.
1986: B R MacDonald; G R Mundy; S Clark; E A Wang; Thomas Kuehl; E Richard Stanley; David G Roodman
Effects of human recombinant CSF-GM and highly purified CSF-1 on the formation of multinucleated cells with osteoclast characteristics in long-term bone marrow cultures.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1986;1(2):227-33.
1985: David G Roodman; K J Ibbotson; B R MacDonald; Thomas Kuehl; G R Mundy
1,25-Dihydroxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(23):8213-7.
1985: David G Roodman; John VandeBerg; Thomas Kuehl
Expression of latent hematopoietic progenitor cells in cultures of newborn and adult baboon liver.
Blood 1985;65(6):1518-25.
1985: David G Roodman
Changes in the growth requirements of baboon liver hematopoietic progenitors during ontogeny.
Progress in clinical and biological research 1985;193():43-54.
1984: K J Ibbotson; David G Roodman; Linda McManus; G R Mundy
Identification and characterization of osteoclast-like cells and their progenitors in cultures of feline marrow mononuclear cells.
The Journal of cell biology 1984;99(2):471-80.
1983: David G Roodman; V W Horadam; T L Wright
Inhibition of erythroid colony formation by autologous bone marrow adherent cells from patients with the anemia of chronic disease.
Blood 1983;62(2):406-12.
1983: David G Roodman; J Lee; A S Gidari
Effects of dexamethasone on erythroid colony and burst formation from human fetal liver and adult marrow.
British journal of haematology 1983;53(4):621-8.
1982: David G Roodman; C N Clare; G Mills
Congenital dyserythropoietic anaemia type II (CDA-II): chromosomal banding studies and adherent cell effects on erythroid colony (CFU-E) and burst (BFU-E) formation.
British journal of haematology 1982;50(3):499-507.
1981: David G Roodman; Jerry L Spivak; E D Zanjani
Stimulation of erythroid colony formation in vitro by erythropoietin immobilized on agarose-bound lectins.
The Journal of laboratory and clinical medicine 1981;98(5):684-90.
1981: David G Roodman; J M Kaplan; M E Kaplan; E D Zanjani
Effects of shortened erythropoietin exposure on sheep marrow cultures.
British journal of haematology 1981;47(2):195-201.
1980: David G Roodman; J L Ascensao; M Banisadre; P M Bloom; E D Zanjani
Autoimmune pancytopenia. Lymphocyte inhibition of autologous but not allogenic bone marrow growth in vitro.
The American journal of medicine 1980;69(2):325-8.
1980: David G Roodman; E P Reese; J M Cardamone
Aplastic anemia associated with rubber cement used by a marathon runner.
Archives of internal medicine 1980;140(5):703.
1979: David G Roodman; E D Zanjani
Endogenous erythroid colony-forming cells in fetal and newborn sheep.
The Journal of laboratory and clinical medicine 1979;94(5):699-707.
1976: David G Roodman; J J Hutton; F J Bollum
DNA polymerase, thymidine kinase and DNA synthesis in erythropoietic mouse spleen cells separated on bovine serum albumin gradients.
Biochimica et biophysica acta 1976;425(4):478-91.
1975: David G Roodman; J J Hutton; F J Bollum
DNA polymerase activities during erythropoiesis. Effects of erythropietin, vinblastine, colcemid, and daunomycin.
Experimental cell research 1975;91(2):269-78.