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Kwablah Awadzi

Research Profile

Disorders

Chemicals & Drugs

Anatomy

Skin
Eye

Geographic Areas

Ghana

Procedures

Concepts & Ideas

Drug Dose Response Relationship

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Publications

TOP 3
Boakye A Boatin; Héctor H García; Andréa Gazzinelli; Warwick N Grant; James S McCarthy; Eliézer K N'Goran; Mike Y Osei-Atweneboana; Roger K Prichard; Banchob Sripa; Guo-Jing Yang; Kwablah Awadzi; Rashida M Barakat; María-Gloria Basáñez; Sara Lustigman
A research agenda for helminth diseases of humans: towards control and elimination.
Mike Y Osei-Atweneboana; Kwablah Awadzi; Simon K Attah; Daniel Boakye; John O Gyapong; Roger K Prichard
Phenotypic evidence of emerging ivermectin resistance in Onchocerca volvulus.
Thomas S Churcher; S D S Pion; Mike Y Osei-Atweneboana; Roger K Prichard; Kwablah Awadzi; Michel Boussinesq; Richard C Collins; James A Whitworth; María-Gloria Basáñez
Identifying sub-optimal responses to ivermectin in the treatment of River Blindness.

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All Publications

2012: Boakye A Boatin; Héctor H García; Andréa Gazzinelli; Warwick N Grant; James S McCarthy; Eliézer K N'Goran; Mike Y Osei-Atweneboana; Roger K Prichard; Banchob Sripa; Guo-Jing Yang; Kwablah Awadzi; Rashida M Barakat; María-Gloria Basáñez; Sara Lustigman
A research agenda for helminth diseases of humans: towards control and elimination.
PLoS neglected tropical diseases 2012;6(4):e1547.
2011: Mike Y Osei-Atweneboana; Kwablah Awadzi; Simon K Attah; Daniel Boakye; John O Gyapong; Roger K Prichard
Phenotypic evidence of emerging ivermectin resistance in Onchocerca volvulus.
PLoS neglected tropical diseases 2011;5(3):e998.
2009: Thomas S Churcher; S D S Pion; Mike Y Osei-Atweneboana; Roger K Prichard; Kwablah Awadzi; Michel Boussinesq; Richard C Collins; James A Whitworth; María-Gloria Basáñez
Identifying sub-optimal responses to ivermectin in the treatment of River Blindness.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(39):16716-21.
2009: Mark J Taylor; Kwablah Awadzi; María-Gloria Basáñez; Nana Biritwum; Daniel Boakye; Boakye A Boatin; Moses Bockarie; Thomas S Churcher; Alexander Yaw Debrah; Geoffrey Edwards; Achim Hoerauf; Sabine Mand; Graham Matthews; Mike Osei-Atweneboana; Roger K Prichard; Samuel Wanji; Ohene Adjei
Onchocerciasis Control: Vision for the Future from a Ghanian perspective.
Parasites & vectors 2009;2(1):7.
2006: J K L Eng; William J Blackhall; Mike Y Osei-Atweneboana; Catherine Bourguinat; D Galazzo; Robin N Beech; T R Unnasch; Kwablah Awadzi; George W Lubega; Roger K Prichard
Ivermectin selection on beta-tubulin: evidence in Onchocerca volvulus and Haemonchus contortus.
Molecular and biochemical parasitology 2006;150(2):229-35.
2004: Kwablah Awadzi; G Edwards; NO Opoku; AE Ardrey; S Favager; ET Addy; SK Attah; L K Yamuah; BT Quartey
The safety, tolerability and pharmacokinetics of levamisole alone, levamisole plus ivermectin, and levamisole plus albendazole, and their efficacy against Onchocerca volvulus.
Annals of tropical medicine and parasitology 2004;98(6):595-614.
2004: Kwablah Awadzi; SK Attah; ET Addy; NO Opoku; BT Quartey; J K Lazdins-Helds; K Ahmed; B A Boatin; Daniel Boakye; G Edwards
Thirty-month follow-up of sub-optimal responders to multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana.
Annals of tropical medicine and parasitology 2004;98(4):359-70.
2004: Kwablah Awadzi; Daniel Boakye; G Edwards; NO Opoku; SK Attah; Mike Y Osei-Atweneboana; J K Lazdins-Helds; AE Ardrey; ET Addy; BT Quartey; K Ahmed; B A Boatin; E W Soumbey-Alley
An investigation of persistent microfilaridermias despite multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana.
Annals of tropical medicine and parasitology 2004;98(3):231-49.
2003: Kwablah Awadzi; G Edwards; Brian O L Duke; NO Opoku; SK Attah; ET Addy; AE Ardrey; BT Quartey
The co-administration of ivermectin and albendazole--safety, pharmacokinetics and efficacy against Onchocerca volvulus.
Annals of tropical medicine and parasitology 2003;97(2):165-78.
2002: Philip J Cooper; Lawrence B Schwartz; Anne-Marie Irani; Kwablah Awadzi; Ronald H Guderian; Thomas B Nutman
Association of transient dermal mastocytosis and elevated plasma tryptase levels with development of adverse reactions after treatment of onchocerciasis with ivermectin.
The Journal of infectious diseases 2002;186(9):1307-13.
2002: Gabriel E Guzmán; Kwablah Awadzi; NO Opoku; R B Narayanan; Hannah Akuffo
Comparison between the skin snip test and simple dot blot assay as potential rapid assessment tools for Onchocerciasis in the postcontrol era in Ghana.
Clinical and diagnostic laboratory immunology 2002;9(5):1014-20.
2002: Paul B Keiser; Stacey M Reynolds; Kwablah Awadzi; Eric A Ottesen; Mark J Taylor; Thomas B Nutman
Bacterial endosymbionts of Onchocerca volvulus in the pathogenesis of posttreatment reactions.
The Journal of infectious diseases 2002;185(6):805-11.
2000: Richard John Horton; C Witt; Eric A Ottesen; Janis Lazdins; David G Addiss; Kwablah Awadzi; Michael J Beach; Vicente Y Belizario; Samuel K Dunyo; M Espinel; John O Gyapong; M Hossain; MM Ismail; RL Jayakody; Patrick J Lammie; W Makunde; D Richard-Lenoble; B Selve; R K Shenoy; Paul Simonsen; Claire N Wamae; Mirani V Weerasooriya
An analysis of the safety of the single dose, two drug regimens used in programmes to eliminate lymphatic filariasis.
Parasitology 2000;121 Suppl():S147-60.
1999: Kwablah Awadzi; SK Attah; ET Addy; NO Opoku; BT Quartey
The effects of high-dose ivermectin regimens on Onchocerca volvulus in onchocerciasis patients.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1999;93(2):189-94.
1999: Philip J Cooper; Kwablah Awadzi; Eric A Ottesen; D Remick; Thomas B Nutman
Eosinophil sequestration and activation are associated with the onset and severity of systemic adverse reactions following the treatment of onchocerciasis with ivermectin.
The Journal of infectious diseases 1999;179(3):738-42.
1997: Kwablah Awadzi
Research notes from the Onchocerciasis Chemotherapy Research Centre, Ghana.
Annals of tropical medicine and parasitology 1997;91(7):703-11.
1997: Kwablah Awadzi; NO Opoku; SK Attah; ET Addy; Brian O L Duke; P K Nyame; N A Kshirsagar
The safety and efficacy of amocarzine in African onchocerciasis and the influence of ivermectin on the clinical and parasitological response to treatment.
Annals of tropical medicine and parasitology 1997;91(3):281-96.
1996: D Adam Plier; Kwablah Awadzi; David Freedman
Immunoregulation in onchocerciasis: persons with ocular inflammatory disease produce a Th2-like response to Onchocerca volvulus antigen.
The Journal of infectious diseases 1996;174(2):380-6.
1996: J B Hagan; K R Bartemes; Hirohito Kita; E A Ottesen; Kwablah Awadzi; T B Nutman; G J Gleich
Elevations in granulocyte-macrophage colony-stimulating factor and interleukin-5 levels precede posttreatment eosinophilia in onchocerciasis.
The Journal of infectious diseases 1996;173(5):1277-80.
1996: Catharina Lavebratt; Gunnel Dalhammar; Kwablah Awadzi; Hannah Akuffo
Field diagnosis of onchocerciasis in an area of high versus low endemicity: evaluation of the Dot Blot Assay.
Scandinavian journal of infectious diseases 1996;28(1):75-81.
1995: Kwablah Awadzi; ET Addy; NO Opoku; Anita Plenge-Bönig; Dietrich W Büttner
The chemotherapy of onchocerciasis XX: ivermectin in combination with albendazole.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1995;46(4):213-20.
1995: Kwablah Awadzi; NO Opoku; ET Addy; B T Quartey
The chemotherapy of onchocerciasis. XIX: The clinical and laboratory tolerance of high dose ivermectin.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1995;46(2):131-7.
1995: Kwablah Awadzi; M Hero; NO Opoku; ET Addy; Dietrich W Büttner; C D Ginger
The chemotherapy of onchocerciasis XVIII. Aspects of treatment with suramin.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1995;46(1):19-26.
1994: Kassa Darge; Jochen Troeger; C Engelke; Michael Leichsenring; Mathias Nelle; Kwablah Awadzi; D W Buettner
Evaluation of ultrasonography for the detection of drug-induced changes in onchocercal nodules.
The American journal of tropical medicine and hygiene 1994;51(6):800-8.
1994: W R Wilson; R S Tuan; K J Shepley; David Freedman; B M Greene; Kwablah Awadzi; Thomas R Unnasch
The Onchocerca volvulus homologue of the multifunctional polypeptide protein disulfide isomerase.
Molecular and biochemical parasitology 1994;68(1):103-17.
1994: David Freedman; Thomas R Unnasch; Anthony Merriweather; Kwablah Awadzi
Truly infection-free persons are rare in areas hyperendemic for African onchocerciasis.
The Journal of infectious diseases 1994;170(4):1054-5.
1994: Kwablah Awadzi; M Hero; NO Opoku; Dietrich W Büttner; P A Coventry; M A Prime; M L Orme; G Edwards
The chemotherapy of onchocerciasis XVII. A clinical evaluation of albendazole in patients with onchocerciasis; effects of food and pretreatment with ivermectin on drug response and pharmacokinetics.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1994;45(3):203-8.
1994: P F Turner; K A Rockett; E A Ottesen; H Francis; Kwablah Awadzi; I A Clark
Interleukin-6 and tumor necrosis factor in the pathogenesis of adverse reactions after treatment of lymphatic filariasis and onchocerciasis.
The Journal of infectious diseases 1994;169(5):1071-5.
1994: S K Tagboto; S Townson; Vincent Pryde Kehdingha Titanji; Kwablah Awadzi; J Castro; G Zea-Flores
Comparison of the sensitivity of different geographical isolates of Onchocerca volvulus microfilariae to ivermectin: effects of exposure to drug on development in the blackfly Simulium ornatum.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1994;88(2):237-41.
1994: S Townson; S K Tagboto; J Castro; A Lujan; Kwablah Awadzi; Vincent Pryde Kehdingha Titanji
Comparison of the sensitivity of different geographical races of Onchocerca volvulus microfilariae to ivermectin: studies in vitro.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1994;88(1):101-6.
1992: Kwablah Awadzi; H M Gilles
Diethylcarbamazine in the treatment of patients with onchocerciasis.
British journal of clinical pharmacology 1992;34(4):281-8.
1992: M Hero; A C Bird; Kwablah Awadzi
Quantification of the ocular reactions to microfilaricides in the chemotherapy of onchocerciasis.
Eye (London, England) 1992;6 ( Pt 1)():93-6.
1991: Kwablah Awadzi; M Hero; O Opoku; Dietrich W Büttner; H M Gilles
The chemotherapy of onchocerciasis. XV. Studies with albendazole.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1991;42(4):356-60.
1991: A P Limaye; J S Abrams; J E Silver; Kwablah Awadzi; H F Francis; E A Ottesen; Thomas B Nutman
Interleukin-5 and the posttreatment eosinophilia in patients with onchocerciasis.
The Journal of clinical investigation 1991;88(4):1418-21.
1991: P E Hoaksey; Kwablah Awadzi; Stephen A Ward; P A Coventry; M L Orme; Geoffrey Edwards
Rapid and sensitive method for the determination of albendazole and albendazole sulphoxide in biological fluids.
Journal of chromatography 1991;566(1):244-9.
1991: H M Gilles; Kwablah Awadzi
The conquest of 'river blindness'.
Annals of tropical medicine and parasitology 1991;85(1):97-101.
1990: Kwablah Awadzi; H Schulz-Key; G Edwards; A Breckenridge; M Orme; H Gilles
The chemotherapy of onchocerciasis. XIV. Studies with mebendazole citrate.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1990;41(4):383-6.
1990: J B Lecaillon; J P Dubois; Kwablah Awadzi; A A Poltera; C D Ginger
Pharmacokinetics of CGP 6140 (amocarzine) after oral administration of single 100-1600 mg doses to patients with onchocerciasis.
British journal of clinical pharmacology 1990;30(4):625-8.
1990: Richard D Semba; R P Murphy; H S Newland; Kwablah Awadzi; B M Greene; Hugh R Taylor
Longitudinal study of lesions of the posterior segment in onchocerciasis.
Ophthalmology 1990;97(10):1334-41.
1990: S J Lee; H L Francis; Kwablah Awadzi; E A Ottesen; Thomas B Nutman
Changes in antibody profile after treatment of human onchocerciasis.
The Journal of infectious diseases 1990;162(2):529-33.
1990: Steven J Ackerman; G M Kephart; H Francis; Kwablah Awadzi; G J Gleich; E A Ottesen
Eosinophil degranulation. An immunologic determinant in the pathogenesis of the Mazzotti reaction in human onchocerciasis.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(10):3961-9.
1990: Dietrich W Büttner; Kwablah Awadzi; NO Opoku
Histological studies of onchocercomata from an area with interrupted transmission in Ghana.
Acta Leidensia 1990;59(1-2):49-50.
1990: M Orme; Geoffrey Edwards; Kwablah Awadzi; A Breckenridge
Clinical pharmacokinetics of drugs against onchocerciasis.
Acta Leidensia 1990;59(1-2):329-42.
1990: Kwablah Awadzi; KY Dadzie; G De Sole; J Remme
Reactions to ivermectin treatment in onchocerciasis patients.
Acta Leidensia 1990;59(1-2):193-9.
1989: Chi-Chao Chan; E A Ottesen; Kwablah Awadzi; R Badu; Robert B Nussenblatt
Immunopathology of ocular onchocerciasis. I. Inflammatory cells infiltrating the anterior segment.
Clinical and experimental immunology 1989;77(3):367-72.
1989: Kwablah Awadzi; KY Dadzie; S Kläger; H M Gilles
The chemotherapy of onchocerciasis. XIII. Studies with ivermectin in onchocerciasis patients in northern Ghana, a region with long lasting vector control.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1989;40(3):361-6.
1989: KY Dadzie; Kwablah Awadzi; A C Bird; H Schulz-Key
Ophthalmological results from a placebo controlled comparative 3-dose ivermectin study in the treatment of onchocerciasis.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1989;40(3):355-60.
1989: G De Sole; Kwablah Awadzi; J Remme; KY Dadzie; O Ba; J Giese; M Karam; F M Keita; NO Opoku
A community trial of ivermectin in the onchocerciasis focus of Asubende, Ghana. II. Adverse reactions.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1989;40(3):375-82.
1989: G De Sole; J Remme; Kwablah Awadzi; S Accorsi; Edoh S Alley; O Ba; KY Dadzie; J Giese; M Karam; F M Keita
Adverse reactions after large-scale treatment of onchocerciasis with ivermectin: combined results from eight community trials.
Bulletin of the World Health Organization 1989;67(6):707-19.
1988: M Orme; Kwablah Awadzi; G Edwards; Alasdair M Breckenridge
Drug treatment of onchocerciasis.
The Quarterly journal of medicine 1988;66(251):195-201.
1987: A J Fulford; S B Macfarlane; Kwablah Awadzi; D R Bell; H M Gilles
The chemotherapy of onchocerciasis. XII. The prediction of microfilarial loads in patients with onchocerciasis after treatment with diethylcarbamazine in northern Ghana.
Annals of tropical medicine and parasitology 1987;81(6):701-11.
1987: C C Chan; Robert B Nussenblatt; M K Kim; A G Palestine; Kwablah Awadzi; E A Ottesen
Immunopathology of ocular onchocerciasis. 2. Anti-retinal autoantibodies in serum and ocular fluids.
Ophthalmology 1987;94(4):439-43.
1987: KY Dadzie; A C Bird; Kwablah Awadzi; H Schulz-Key; H M Gilles; M A Aziz
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
The British journal of ophthalmology 1987;71(2):78-85.
1986: Kwablah Awadzi; KY Dadzie; H Schulz-Key; H M Gilles; A J Fulford; M A Aziz
The chemotherapy of onchocerciasis. XI. A double-blind comparative study of ivermectin, diethylcarbamazine and placebo in human onchocerciasis in northern Ghana.
Annals of tropical medicine and parasitology 1986;80(4):433-42.
1986: Kwablah Awadzi; K K Adjepon-Yamoah; G Edwards; M L Orme; A M Breckenridge; H M Gilles
The effect of moderate urine alkalinisation on low dose diethylcarbamazine therapy in patients with onchocerciasis.
British journal of clinical pharmacology 1986;21(6):669-76.
1985: G Edwards; C L Rodick; S A Ward; Kwablah Awadzi; M L Orme; A M Breckenridge
Determination of suramin in plasma by high-performance liquid chromatography.
Journal of chromatography 1985;343(1):224-8.
1985: H Francis; Kwablah Awadzi; E A Ottesen
The Mazzotti reaction following treatment of onchocerciasis with diethylcarbamazine: clinical severity as a function of infection intensity.
The American journal of tropical medicine and hygiene 1985;34(3):529-36.
1985: H R Taylor; Kwablah Awadzi; T George; H Schulz-Key; R P Murphy
Fluorescein angiographic studies of mebendazole treatment for onchocerciasis.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1985;36(1):7-11.
1985: Kwablah Awadzi; KY Dadzie; H Shulz-Key; D R Haddock; H M Gilles; M A Aziz
The chemotherapy of onchocerciasis X. An assessment of four single dose treatment regimes of MK-933 (ivermectin) in human onchocerciasis.
Annals of tropical medicine and parasitology 1985;79(1):63-78.
1984: Kwablah Awadzi; KY Dadzie; H Schulz-Key; D R Haddock; H M Gilles; M A Aziz
Ivermectin in onchocerciasis.
Lancet 1984;2(8408):921.
1984: A Breckenridge; Kwablah Awadzi; D J Back; G Edwards; H Gilles; M Orme; S Ward
Drug metabolism and tropical disease.
Biochemical Society transactions 1984;12(1):90-5.
1982: Kwablah Awadzi; M L Orme; A M Breckenridge; H M Gilles
The chemotherapy of onchocerciasis IX. The effect of prednisone plus cyproheptadine on the Mazzotti reaction.
Annals of tropical medicine and parasitology 1982;76(5):547-55.
1982: Kwablah Awadzi; H Schulz-Key; R E Howells; D R Haddock; H M Gilles
The chemotherapy of onchocerciasis VIII Levamisole and its combination with the benzimidazoles.
Annals of tropical medicine and parasitology 1982;76(4):459-73.
1982: Kwablah Awadzi; M L Orme; A M Breckenridge; H M Gilles
The chemotherapy of onchocerciasis VII. The effect of prednisone on the Mazzotti reaction.
Annals of tropical medicine and parasitology 1982;76(3):331-8.
1982: Kwablah Awadzi; M L Orme; A M Breckenridge; H M Gilles
The chemotherapy of onchocerciasis VI. The effect of indomethacin and cyproheptadine on the Mazzotti reaction.
Annals of tropical medicine and parasitology 1982;76(3):323-30.
1981: G Edwards; Kwablah Awadzi; A M Breckenridge; H M Gilles; M L Orme; S A Ward
Diethylcarbamazine disposition in patients with onchocerciasis.
Clinical pharmacology and therapeutics 1981;30(4):551-7.
1981: Kwablah Awadzi; M L Orme; A M Breckenridge; D Haddock; H M Gilles
Studies of metrifonate in onchocerciasis.
Acta pharmacologica et toxicologica 1981;49 Suppl 5():131-6.
1980: Kwablah Awadzi; H M Gilles
The chemotherapy of onchocerciasis IV. Further trials with metrifonate.
Annals of tropical medicine and parasitology 1980;74(3):355-62.
1980: Kwablah Awadzi; H Roulet; D R Bell
The chemotherapy of onchocerciasis V. A standard method for the determination of microfilarial density in skin snips.
Annals of tropical medicine and parasitology 1980;74(3):363-6.
1980: Kwablah Awadzi; H M Gilles
The chemotherapy of onchocerciasis iii. A comparative study of diethylcarbamazide (DEC) and metrifonate.
Annals of tropical medicine and parasitology 1980;74(2):199-210.
1980: Kwablah Awadzi
The chemotherapy of onchocerciasis II. Quantitation of the clinical reaction to microfilaricides.
Annals of tropical medicine and parasitology 1980;74(2):189-97.
1980: Kwablah Awadzi; D R Haddock; H M Gilles
The chemotherapy of onchocerciasis I. Initial open evaluation of metrifonate.
Annals of tropical medicine and parasitology 1980;74(1):53-61.