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John Kenneth Cowell
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17
Rossi, Michael
16
Nowak, Norma
12
Sossey-Alaoui, Khalid
12
Still, Ivan
11
Pritchard, Jon
11
Hawthorn, Lesleyann
10
Chernova, Olga
10
Kunapuli, Padmaja
9
Lo, Ken
9
Onadim, Zerrin
8
Roberts, T
8
Matsui, Sei-Ichi
7
Conroy, Jeffrey
6
Burkhardt, Tania
6
LaDuca, Jeffrey
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All Publications
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2009: Kunapuli Padmaja; Jang Geeng-Fu; Kazim Latif; Cowell John K
Mass spectrometry identifies LGI1-interacting proteins that are involved in synaptic vesicle function in the human brain.
Journal of molecular neuroscience : MN 2009;39(1-2):137-43.
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2009: Kasyapa Chitta; Gu Ting-Lei; Natarajan Lalitha; Polakiewicz Roberto; Cowell John K
Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific MS.
Proteomics 2009;9(16):3979-88.
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2009: Ren Mingqiang; Li Xiurong; Cowell John K
Genetic fingerprinting of the development and progression of T-cell lymphoma in a murine model of atypical myeloproliferative disorder initiated by the ZNF198-fibroblast growth factor receptor-1 chimeric tyrosine kinase.
Blood 2009;114(8):1576-84.
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2009: Bruce Heather A; Sachs Nancy; Rudnicki Dobrila D; Lin Stephanie G; Willour Virginia L; Cowell John K; Conroy Jeffrey; McQuaid Devin E; Rossi Michael; Gaile Daniel P; Nowak Norma J; Holmes Susan E; Sklar Pamela; Ross Christopher A; Delisi Lynn E; Margolis Russell L
Long tandem repeats as a form of genomic copy number variation: structure and length polymorphism of a chromosome 5p repeat in control and schizophrenia populations.
Psychiatric genetics 2009;19(2):64-71.
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2009: Cowell John K; Lo Ken C
Application of oligonucleotides arrays for coincident comparative genomic hybridization, ploidy status and loss of heterozygosity studies in human cancers.
Methods in molecular biology (Clifton, N.J.) 2009;556():47-65.
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2008: Lo Ken C; Chalker Jane; Strehl Sabine; Neat Michael; Smith Owen; Dastugue Nicole; Kearney Lyndal; Izraeli Shai; Kempski Helena; Cowell John K
Array comparative genome hybridization analysis of acute lymphoblastic leukaemia and acute megakaryoblastic leukaemia in patients with Down syndrome.
British journal of haematology 2008;142(6):934-45.
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2008: Lo Ken C; Bailey Dione; Burkhardt Tania; Gardina Paul; Turpaz Yaron; Cowell John K
Comprehensive analysis of loss of heterozygosity events in glioblastoma using the 100K SNP mapping arrays and comparison with copy number abnormalities defined by BAC array comparative genomic hybridization.
Genes, chromosomes & cancer 2008;47(3):221-37.
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2008: Lo Ken C; Stein Leighton C; Panzarella Jenniffer A; Cowell John K; Hawthorn Lesleyann
Identification of genes involved in squamous cell carcinoma of the lung using synchronized data from DNA copy number and transcript expression profiling analysis.
Lung cancer (Amsterdam, Netherlands) 2008;59(3):315-31.
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2008: Rossi Michael R; Laduca Jeff; Cowell John K; Srivastava Bejai I S; Matsui Seiichi
Genomic analysis of CD8+ NK/T cell line, 'SRIK-NKL', with array-based CGH (aCGH), SKY/FISH and molecular mapping.
Leukemia research 2008;32(3):455-63.
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2008: Gardina Paul J; Lo Ken C; Lee Walter; Cowell John K; Turpaz Yaron
Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays.
BMC genomics 2008;9():489.
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2007: Lo Ken C; Ma Changxing; Bundy Brian N; Pomeroy Scott L; Eberhart Charles G; Cowell John K
Gain of 1q is a potential univariate negative prognostic marker for survival in medulloblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7022-8.
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2007: Kasyapa Chitta S; Kunapuli Padmaja; Cowell John K
HSPA1A is an important regulator of the stability and function of ZNF198 and its oncogenic derivative, ZNF198-FGFR1.
Journal of cellular biochemistry 2007;102(5):1308-17.
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2007: Lo Ken C; Rossi Michael R; LaDuca Jeffrey; Hicks David G; Turpaz Yaron; Hawthorn Lesleyann; Cowell John K
Candidate glioblastoma development gene identification using concordance between copy number abnormalities and gene expression level changes.
Genes, chromosomes & cancer 2007;46(10):875-94.
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2007: Sossey-Alaoui Khalid; Li Xiurong; Cowell John K
c-Abl-mediated phosphorylation of WAVE3 is required for lamellipodia formation and cell migration.
The Journal of biological chemistry 2007;282(36):26257-65.
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2007: Lo Ken C; Rossi Michael R; Eberhart Charles G; Cowell John K
Genome wide copy number abnormalities in pediatric medulloblastomas as assessed by array comparative genome hybridization.
Brain pathology (Zurich, Switzerland) 2007;17(3):282-96.
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2007: Sossey-Alaoui Khalid; Safina Alfiya; Li Xiurong; Vaughan Mary M; Hicks David G; Bakin Andrei V; Cowell John K
Down-regulation of WAVE3, a metastasis promoter gene, inhibits invasion and metastasis of breast cancer cells.
The American journal of pathology 2007;170(6):2112-21.
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2007: Ford Richard J; Shen Long; Lin-Lee Yen Chiu; Pham Lan V; Multani Asha; Zhou Hai-Jun; Tamayo Archito T; Zhang ChongJie; Hawthorn Lesleyann; Cowell John K; Ambrus Julian L
Development of a murine model for blastoid variant mantle-cell lymphoma.
Blood 2007;109(11):4899-906.
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2007: Head Karen; Gong Shiaoching; Joseph Sheldon; Wang Cuidong; Burkhardt Tania; Rossi Michael R; LaDuca Jeffrey; Matsui Sei-Ichi; Vaughan Mary; Hicks David G; Heintz Nathaniel; Cowell John K
Defining the expression pattern of the LGI1 gene in BAC transgenic mice.
Mammalian genome : official journal of the International Mammalian Genome Society 2007;18(5):328-37.
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2007: Ivanov I; Lo K C; Hawthorn L; Cowell J K; Ionov Y
Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells.
Oncogene 2007;26(20):2873-84.
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2007: Dabbeekeh J T S; Faitar S L; Dufresne C P; Cowell J K
The EVI5 TBC domain provides the GTPase-activating protein motif for RAB11.
Oncogene 2007;26(19):2804-8.
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2007: Wang Jing; Kuropatwinski Karen; Hauser Jennie; Rossi Michael R; Zhou Yunfei; Conway Alexis; Kan Julie L C; Gibson Neil W; Willson James K V; Cowell John K; Brattain Michael G
Colon carcinoma cells harboring PIK3CA mutations display resistance to growth factor deprivation induced apoptosis.
Molecular cancer therapeutics 2007;6(3):1143-50.
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2007: Cowell John K; Hawthorn Lesleyann
The application of microarray technology to the analysis of the cancer genome.
Current molecular medicine 2007;7(1):103-20.
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2007: Lo Ken C; Rossi Michael R; Burkhardt Tania; Pomeroy Scott L; Cowell John K
Overlay analysis of the oligonucleotide array gene expression profiles and copy number abnormalities as determined by array comparative genomic hybridization in medulloblastomas.
Genes, chromosomes & cancer 2007;46(1):53-66.
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2007: Lo Ken C; Shankar Ganesh; Turpaz Yaron; Bailey Dione; Rossi Michael R; Burkhardt Tania; Liang Ping; Cowell John K
Overlay Tool for aCGHViewer: An Analysis Module Built for aCGHViewer used to Perform Comparisons of Data Derived from Different Microarray Platforms.
Cancer informatics 2007;3():307-19.
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2006: Wetzler Meir; Brady Michael T; Tracy Erin; Li Zhang-Rong; Donohue Kathleen A; O'Loughlin Kieran L; Cheng Yijun; Mortazavi Amir; McDonald Amy A; Kunapuli Padmaja; Wallace Paul K; Baer Maria R; Cowell John K; Baumann Heinz
Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(22):6817-25.
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2006: Kunapuli Padmaja; Kasyapa Chitta S; Chin Suet-Feung; Caldas Carlos; Cowell John K
ZNF198, a zinc finger protein rearranged in myeloproliferative disease, localizes to the PML nuclear bodies and interacts with SUMO-1 and PML.
Experimental cell research 2006;312(19):3739-51.
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2006: Shen Long; Zhang Chongjie; Wang Tao; Brooks Stephen; Ford Richard J; Lin-Lee Yen Chiu; Kasianowicz Amy; Kumar Vijay; Martin Lisa; Liang Ping; Cowell John; Ambrus Julian L
Development of autoimmunity in IL-14alpha-transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5676-86.
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2006: Faitar Silviu L; Sossey-Alaoui Khalid; Ranalli Tamara A; Cowell John K
EVI5 protein associates with the INCENP-aurora B kinase-survivin chromosomal passenger complex and is involved in the completion of cytokinesis.
Experimental cell research 2006;312(12):2325-35.
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2006: Kasyapa Chitta S; Kunapuli Padmaja; Hawthorn Lesleyann; Cowell John K
Induction of the plasminogen activator inhibitor-2 in cells expressing the ZNF198/FGFR1 fusion kinase that is involved in atypical myeloproliferative disease.
Blood 2006;107(9):3693-9.
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2006: Rossi Michael R; Conroy Jeffrey; McQuaid Devin; Nowak Norma J; Rutka James T; Cowell John K
Array CGH analysis of pediatric medulloblastomas.
Genes, chromosomes & cancer 2006;45(3):290-303.
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2006: Mason Douglas X; Keppler Daniel; Zhang Jun; Jackson Tonya J; Seger Yvette R; Matsui Seiichi; Abreo Fleurette; Cowell John K; Hannon Gregory J; Lowe Scott W; Lin Athena W
Defined genetic events associated with the spontaneous in vitro transformation of ElA/Ras-expressing human IMR90 fibroblasts.
Carcinogenesis 2006;27(2):350-9.
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2006: Shankar Ganesh; Rossi Michael R; McQuaid Devin E; Conroy Jeffrey M; Gaile Daniel G; Cowell John K; Nowak Norma J; Liang Ping
aCGHViewer: A Generic Visualization Tool For aCGH data.
Cancer informatics 2006;2():36-43.
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2005: Rossi Michael R; Ionov Yurij; Bakin Andrei V; Cowell John K
Truncating mutations in the ACVR2 gene attenuates activin signaling in prostate cancer cells.
Cancer genetics and cytogenetics 2005;163(2):123-9.
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2005: Rossi Michael R; La Duca Jeffrey; Matsui Sei-Ichi; Nowak Norma J; Hawthorn Lesleyann; Cowell John K
Novel amplicons on the short arm of chromosome 7 identified using high resolution array CGH contain over expressed genes in addition to EGFR in glioblastoma multiforme.
Genes, chromosomes & cancer 2005;44(4):392-404.
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2005: Deeb George; Baer Maria R; Gaile Daniel P; Sait Sheila N Jani; Barcos Maurice; Wetzler Meir; Conroy Jeffrey M; Nowak Norma J; Cowell John K; Cheney Richard T
Genomic profiling of myeloid sarcoma by array comparative genomic hybridization.
Genes, chromosomes & cancer 2005;44(4):373-83.
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2005: Lassman Andrew B; Rossi Michael R; Raizer Jeffrey J; Abrey Lauren E; Lieberman Frank S; Grefe Chelsea N; Lamborn Kathleen; Pao William; Shih Alan H; Kuhn John G; Wilson Richard; Nowak Norma J; Cowell John K; DeAngelis Lisa M; Wen Patrick; Gilbert Mark R; Chang Susan; Yung W A; Prados Michael; Holland Eric C
Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7841-50.
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2005: Cowell John K; LaDuca Jeffrey; Rossi Michael R; Burkhardt Tania; Nowak Norma J; Matsui Sei-ichi
Molecular characterization of the t(3;9) associated with immortalization in the MCF10A cell line.
Cancer genetics and cytogenetics 2005;163(1):23-9.
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2005: Faitar Silviu L; Dabbeekeh Jeremy T S; Ranalli Tamara A; Cowell John K
EVI5 is a novel centrosomal protein that binds to alpha- and gamma-tubulin.
Genomics 2005;86(5):594-605.
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2005: Rossi Michael R; Hawthorn Lesleyann; Platt Julie; Burkhardt Tania; Cowell John K; Ionov Yurij
Identification of inactivating mutations in the JAK1, SYNJ2, and CLPTM1 genes in prostate cancer cells using inhibition of nonsense-mediated decay and microarray analysis.
Cancer genetics and cytogenetics 2005;161(2):97-103.
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2005: Kasyapa Chitta S; Kunapuli Padmaja; Cowell John K
Mass spectroscopy identifies the splicing-associated proteins, PSF, hnRNP H3, hnRNP A2/B1, and TLS/FUS as interacting partners of the ZNF198 protein associated with rearrangement in myeloproliferative disease.
Experimental cell research 2005;309(1):78-85.
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2005: Rossi Michael R; Gaile Daniel; Laduca Jeffrey; Matsui Sei-Ichi; Conroy Jeffrey; McQuaid Devin; Chervinsky David; Eddy Roger; Chen Hai-Shen; Barnett Gene H; Nowak Norma J; Cowell John K
Identification of consistent novel submegabase deletions in low-grade oligodendrogliomas using array-based comparative genomic hybridization.
Genes, chromosomes & cancer 2005;44(1):85-96.
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2005: Nowak Norma J; Gaile Daniel; Conroy Jeffrey M; McQuaid Devin; Cowell John; Carter Randy; Goggins Michael G; Hruban Ralph H; Maitra Anirban
Genome-wide aberrations in pancreatic adenocarcinoma.
Cancer genetics and cytogenetics 2005;161(1):36-50.
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2005: Rossi Michael R; Huntoon Kristin; Cowell John K
Differential expression of the LGI and SLIT families of genes in human cancer cells.
Gene 2005;356():85-90.
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2005: Sossey-Alaoui Khalid; Ranalli Tamara A; Li Xiurong; Bakin Andrei V; Cowell John K
WAVE3 promotes cell motility and invasion through the regulation of MMP-1, MMP-3, and MMP-9 expression.
Experimental cell research 2005;308(1):135-45.
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2005: Sossey-Alaoui Khalid; Li Xiurong; Ranalli Tamara A; Cowell John K
WAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinase.
The Journal of biological chemistry 2005;280(23):21748-55.
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2005: Matsui Sei-Ichi; LaDuca Jeffrey; Rossi Michael R; Nowak Norma J; Cowell John K
Molecular characterization of a consistent 4.5-megabase deletion at 4q28 in prostate cancer cells.
Cancer genetics and cytogenetics 2005;159(1):18-26.
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2005: Cowell J K; Morris J A; Tawn E J
Analysis of the RB1 gene in children with retinoblastoma having residential connections to West Cumbria, England.
Journal of radiological protection : official journal of the Society for Radiological Protection 2005;25(1):89-92.
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2004: Cowell John K
High throughput determination of gains and losses of genetic material using high resolution BAC arrays and comparative genomic hybridization.
Combinatorial chemistry & high throughput screening 2004;7(6):587-96.
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2004: Bauer Joseph E; Rezaishiraz Hamed; Head Karen; Cowell John; Bepler Gerold; Aiken Miriam; Cummings K Michael; Hyland Andrew
Obtaining DNA from a geographically dispersed cohort of current and former smokers: use of mail-based mouthwash collection and monetary incentives.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2004;6(3):439-46.
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2004: Cowell John K; Matsui Sei-Ichi; Wang Yong D; LaDuca Jeffrey; Conroy Jeffrey; McQuaid Devin; Nowak Norma J
Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme.
Cancer genetics and cytogenetics 2004;151(1):36-51.
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2004: Kunapuli Padmaja; Kasyapa Chitta S; Hawthorn Lesleyann; Cowell John K
LGI1, a putative tumor metastasis suppressor gene, controls in vitro invasiveness and expression of matrix metalloproteinases in glioma cells through the ERK1/2 pathway.
The Journal of biological chemistry 2004;279(22):23151-7.
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2004: Cowell John K; Barnett Gene H; Nowak Norma J
Characterization of the 1p/19q chromosomal loss in oligodendrogliomas using comparative genomic hybridization arrays (CGHa).
Journal of neuropathology and experimental neurology 2004;63(2):151-8.
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2004: Li Xiurong; Cowell John K; Sossey-Alaoui Khalid
CLCA2 tumour suppressor gene in 1p31 is epigenetically regulated in breast cancer.
Oncogene 2004;23(7):1474-80.
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2004: Cowell J K; Wang Y D; Head K; Conroy J; McQuaid D; Nowak N J
Identification and characterisation of constitutional chromosome abnormalities using arrays of bacterial artificial chromosomes.
British journal of cancer 2004;90(4):860-5.
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2004: Ionov Yurij; Matsui Sei-Ichi; Cowell John K
A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1273-8.
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2004: Ionov Yurij; Nowak Norma; Perucho Manuel; Markowitz Sanford; Cowell John K
Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability.
Oncogene 2004;23(3):639-45.
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2003: Kunapuli Padmaja; Chitta Kasyapa S; Cowell John K
Suppression of the cell proliferation and invasion phenotypes in glioma cells by the LGI1 gene.
Oncogene 2003;22(26):3985-91.
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2003: Chernova O B; Barnett G H; Cowell J K
Rapid detection of allelic losses in brain tumours using microsatellite repeat markers and high-performance liquid chromatography.
British journal of cancer 2003;88(12):1889-93.
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2003: Sossey-Alaoui Khalid; Head Karen; Nowak Norma; Cowell John K
Genomic organization and expression profile of the human and mouse WAVE gene family.
Mammalian genome : official journal of the International Mammalian Genome Society 2003;14(5):314-22.
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2003: Kunapuli Padmaja; Somerville Robert; Still Ivan H; Cowell John K
ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins.
Oncogene 2003;22(22):3417-23.
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2003: Beghini Alessandro; Magnani Ivana; Roversi Gaia; Piepoli Tiziana; Di Terlizzi Simona; Moroni Ramona F; Pollo Bianca; Fuhrman Conti Anna M; Cowell John K; Finocchiaro Gaetano; Larizza Lidia
The neural progenitor-restricted isoform of the MARK4 gene in 19q13.2 is upregulated in human gliomas and overexpressed in a subset of glioblastoma cell lines.
Oncogene 2003;22(17):2581-91.
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2003: Baumann Heinz; Kunapuli Padmaja; Tracy Erin; Cowell John K
The oncogenic fusion protein-tyrosine kinase ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors.
The Journal of biological chemistry 2003;278(18):16198-208.
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2003: Matsui Sei-ichi; Faitar Silviu L; Rossi Michael R; Cowell John K
Application of spectral karyotyping to the analysis of the human chromosome complement of interspecies somatic cell hybrids.
Cancer genetics and cytogenetics 2003;142(1):30-5.
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2003: Sossey-Alaoui Khalid; Vieira Luís; David Dezso; Boavida Maria G; Cowell John K
Molecular characterization of a 7p15-21 homozygous deletion in a Wilms tumor.
Genes, chromosomes & cancer 2003;36(1):1-6.
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2003: Cowell John K; Nowak Norma J
High-resolution analysis of genetic events in cancer cells using bacterial artificial chromosome arrays and comparative genome hybridization.
Advances in cancer research 2003;90():91-125.
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2002: Sossey-Alaoui Khalid; Su Guanfang; Malaj Eda; Roe Bruce; Cowell John K
WAVE3, an actin-polymerization gene, is truncated and inactivated as a result of a constitutional t(1;13)(q21;q12) chromosome translocation in a patient with ganglioneuroblastoma.
Oncogene 2002;21(38):5967-74.
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2002: Sossey-Alaoui Khalid; Kitamura Eiko; Head Karen; Cowell John K
Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer.
Genomics 2002;80(1):5-7.
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2002: Tang Shou-Jiang; Dumot John A; Wang Liming; Memmesheimer Christian; Conwell Darwin L; Zuccaro Gregory; Goormastic Marlene; Ormsby Adrian H; Cowell John
Telomerase activity in pancreatic endocrine tumors.
The American journal of gastroenterology 2002;97(4):1022-30.
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2002: Lauffart Brenda; Howell Scott J; Tasch Jason E; Cowell John K; Still Ivan H
Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells.
The Biochemical journal 2002;363(Pt 1):195-200.
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2002: Cowell John K
Epilepsy research gets new guidance.
Nature medicine 2002;8(3):219-20.
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2001: Kitamura E; Kuemerle B A; Chernova O B; Cowell J K
Molecular characterization of the breakpoint region associated with a constitutional t(2;15)(q34;q26) in a patient with multiple myeloma.
Cancer genetics and cytogenetics 2001;129(2):112-9.
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2001: Chernova O B; Hunyadi A; Malaj E; Pan H; Crooks C; Roe B; Cowell J K
A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells.
Oncogene 2001;20(38):5378-92.
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2001: Sossey-Alaoui K; Kitamura E; Cowell J K
Fine mapping of the PTGFR gene to 1p31 region and mutation analysis in human breast cancer.
International journal of molecular medicine 2001;7(5):543-6.
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2001: Evans J J; Jeun S S; Lee J H; Harwalkar J A; Shoshan Y; Cowell J K; Golubic M
Molecular alterations in the neurofibromatosis type 2 gene and its protein rarely occurring in meningothelial meningiomas.
Journal of neurosurgery 2001;94(1):111-7.
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2001: Wang Q; Timur A A; Szafranski P; Sadgephour A; Jurecic V; Cowell J; Baldini A; Driscoll D J
Identification and molecular characterization of de novo translocation t(8;14)(q22.3;q13) associated with a vascular and tissue overgrowth syndrome.
Cytogenetics and cell genetics 2001;95(3-4):183-8.
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2000: Gergely F; Karlsson C; Still I; Cowell J; Kilmartin J; Raff J W
The TACC domain identifies a family of centrosomal proteins that can interact with microtubules.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14352-7.
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2000: Poetsch M; Dittberner T; Cowell J K; Woenckhaus C
TTC4, a novel candidate tumor suppressor gene at 1p31 is often mutated in malignant melanoma of the skin.
Oncogene 2000;19(50):5817-20.
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2000: Kitamura E; Su G; Sossey-Alaoui K; Malaj E; Lewis J; Pan H Q; Hawthorn L; Roe B; Cowell J K
A transcription map of the minimally deleted region from 13q14 in B-cell chronic lymphocytic leukemia as defined by large scale sequencing of the 650 kb critical region.
Oncogene 2000;19(50):5772-80.
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2000: Somerville R P; Chernova O; Liu S; Shoshan Y; Cowell J K
Identification of the promoter, genomic structure, and mouse ortholog of LGI1.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(8):622-7.
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2000: Shoshan Y; Chernova O; Juen S S; Somerville R P; Israel Z; Barnett G H; Cowell J K
Radiation-induced meningioma: a distinct molecular genetic pattern?
Journal of neuropathology and experimental neurology 2000;59(7):614-20.
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2000: Chelsea D M; Roberts T; Cowell J K
A new region of synteny between human chromosome 1p22 and mouse chromosome 5.
International journal of molecular medicine 2000;5(5):553-6.
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2000: Su G; Casey G; Cowell J K
Genomic structure of the human tetratricopeptide repeat-containing gene, TTC4, from chromosome region 1p31 and mutation analysis in breast cancers.
International journal of molecular medicine 2000;5(2):197-200.
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2000: Kushner D M; Paranjape J M; Bandyopadhyay B; Cramer H; Leaman D W; Kennedy A W; Silverman R H; Cowell J K
2-5A antisense directed against telomerase RNA produces apoptosis in ovarian cancer cells.
Gynecologic oncology 2000;76(2):183-92.
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2000: Liu S; Cowell J K
Cloning and characterization of the TATA-less promoter from the human GFI1 proto-oncogene.
Annals of human genetics 2000;64(Pt 1):83-6.
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1999: Still I H; Vince P; Cowell J K
Identification of a novel gene (ADPRTL1) encoding a potential Poly(ADP-ribosyl)transferase protein.
Genomics 1999;62(3):533-6.
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1999: Shoshan Y; Nishiyama A; Chang A; Mörk S; Barnett G H; Cowell J K; Trapp B D; Staugaitis S M
Expression of oligodendrocyte progenitor cell antigens by gliomas: implications for the histogenesis of brain tumors.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(18):10361-6.
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1999: Still I H; Hamilton M; Vince P; Wolfman A; Cowell J K
Cloning of TACC1, an embryonically expressed, potentially transforming coiled coil containing gene, from the 8p11 breast cancer amplicon.
Oncogene 1999;18(27):4032-8.
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1999: Still I H; Vince P; Cowell J K
The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines.
Genomics 1999;58(2):165-70.
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1999: Su G; Roberts T; Cowell J K
TTC4, a novel human gene containing the tetratricopeptide repeat and mapping to the region of chromosome 1p31 that is frequently deleted in sporadic breast cancer.
Genomics 1999;55(2):157-63.
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1998: Chernova O B; Somerville R P; Cowell J K
A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors.
Oncogene 1998;17(22):2873-81.
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1998: Cowell J K; Gallie B L
Which retinoblastoma patients should be screened for RB1 mutations?
European journal of cancer (Oxford, England : 1990) 1998;34(12):1825-6.
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1998: Grundy R G; Pritchard J; Scambler P; Cowell J K
Loss of heterozygosity on chromosome 16 in sporadic Wilms' tumour.
British journal of cancer 1998;78(9):1181-7.
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1998: Somerville R P; Shoshan Y; Eng C; Barnett G; Miller D; Cowell J K
Molecular analysis of two putative tumour suppressor genes, PTEN and DMBT, which have been implicated in glioblastoma multiforme disease progression.
Oncogene 1998;17(13):1755-7.
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1998: Hawthorn L A; Cowell J K
Construction of a bacterial artificial chromosome (BAC) contig across the minimally deleted region in 13q14.3 in B-cell chronic lymphocytic leukemia.
Annals of human genetics 1998;62(Pt 5):401-9.
-
1998: Still I H; Cowell J K
The t(8;13) atypical myeloproliferative disorder: further analysis of the ZNF198 gene and lack of evidence for multiple genes disrupted on chromosome 13.
Blood 1998;92(4):1456-8.
-
1998: Chernova O; Cowell J K
Molecular definition of chromosome translocations involving 10q24 and 19q13 in human malignant glioma cells.
Cancer genetics and cytogenetics 1998;105(1):60-8.
-
1998: Grundy R G; Pritchard J; Scambler P; Cowell J K
Loss of heterozygosity for the short arm of chromosome 7 in sporadic Wilms tumour.
Oncogene 1998;17(3):395-400.
-
1998: Kondo S; Tanaka Y; Kondo Y; Hitomi M; Barnett G H; Ishizaka Y; Liu J; Haqqi T; Nishiyama A; Villeponteau B; Cowell J K; Barna B P
Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(10):801-11.
-
1998: Roberts T; Chernova O; Cowell J K
NB4S, a member of the TBC1 domain family of genes, is truncated as a result of a constitutional t(1;10)(p22;q21) chromosome translocation in a patient with stage 4S neuroblastoma.
Human molecular genetics 1998;7(7):1169-78.
-
1998: Kondo S; Kondo Y; Li G; Silverman R H; Cowell J K
Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA.
Oncogene 1998;16(25):3323-30.
-
1998: Cowell J K; Bia B
A novel missense mutation in patients from a retinoblastoma pedigree showing only mild expression of the tumor phenotype.
Oncogene 1998;16(24):3211-3.
-
1998: Grundy R G; Aledo R; Cowell J K
Characterization of the breakpoints in unbalanced t(5;11)(p15;p15) constitutional chromosome translocations in two patients with beckwith-wiedemann syndrome using fluorescence in situ hybridisation.
International journal of molecular medicine 1998;1(5):801-8.
-
1998: Kondo Y; Kondo S; Tanaka Y; Haqqi T; Barna B P; Cowell J K
Inhibition of telomerase increases the susceptibility of human malignant glioblastoma cells to cisplatin-induced apoptosis.
Oncogene 1998;16(17):2243-8.
-
1998: Chernova O; Still I; Kalaycio M; Hoeltge G; Cowell J K
Characterization of the breakpoints in a t(8;13)(p11;q12) translocation from a patient with myeloproliferative disease using fluorescence in situ hybridization.
Genes, chromosomes & cancer 1998;21(2):160-5.
-
1998: Roberts T; Chernova O; Cowell J K
Molecular characterization of the 1p22 breakpoint region spanning the constitutional translocation breakpoint in a neuroblastoma patient with a t(1;10)(p22;q21).
Cancer genetics and cytogenetics 1998;100(1):10-20.
-
1998: Getman M E; Houseal T W; Miller G A; Grundy P E; Cowell J K; Landes G M
Comparative genomic hybridization and its application to Wilms' tumorigenesis.
Cytogenetics and cell genetics 1998;82(3-4):284-90.
-
1997: Still I H; Chernova O; Hurd D; Stone R M; Cowell J K
Molecular characterization of the t(8;13)(p11;q12) translocation associated with an atypical myeloproliferative disorder: evidence for three discrete loci involved in myeloid leukemias on 8p11.
Blood 1997;90(8):3136-41.
-
1997: Still I H; Vince P; Cowell J K
Direct isolation of human transcribed sequences from yeast artificial chromosomes through the application of RNA fingerprinting.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10373-8.
-
1997: Cowell J K; Ramani P; Song Y; Evans M; Morgan G
The use of SCID mice for the growth of retinoblastoma cell lines and for the establishment of xenografts from primary tumours.
European journal of cancer (Oxford, England : 1990) 1997;33(7):1070-4.
-
1997: Roberts T; Cowell J K
Cloning of the human Gfi-1 gene and its mapping to chromosome region 1p22.
Oncogene 1997;14(8):1003-5.
-
1997: Still I H; Roberts T; Cowell J K
Fine structure physical mapping of a 1.9 Mb region of chromosome 13q12.
Annals of human genetics 1997;61(Pt 1):15-24.
-
1996: Cowell J K; Cragg H
Constitutional nonsense germline mutations in the RB1 gene detected in patients with early onset unilateral retinoblastoma.
European journal of cancer (Oxford, England : 1990) 1996;32A(10):1749-52.
-
1996: Roberts T; Auffray C; Cowell J K
Regional localization of 192 genic markers on human chromosome 1.
Genomics 1996;36(2):337-40.
-
1996: Ramani P; Cowell J K
The expression pattern of Wilms' tumour gene (WT1) product in normal tissues and paediatric renal tumours.
The Journal of pathology 1996;179(2):162-8.
-
1996: Pook M A; Thakrar R; Pottinger B; Harding B; Porteous D; van Heyningen V; Cowell J; Jones C; Povey S; Davies K E; Thakker R V
EagI and NotI linking clones from human chromosomes 11 and Xp.
Human genetics 1996;97(6):742-9.
-
1996: Roberts T; Mead R S; Cowell J K
Characterisation of a human chromosome 1 somatic cell hybrid mapping panel and regional assignment of 6 novel STS.
Annals of human genetics 1996;60(Pt 3):213-20.
-
1996: Still I H; Roberts T; Bia B; Hawthorn L; Auffray C; Cowell J
Incorporation of 35 novel gene transcripts into the physical and genetic map of human chromosome 13.
Genomics 1996;33(2):159-66.
-
1996: Cowell J K; Bia B; Akoulitchev A
A novel mutation in the promotor region in a family with a mild form of retinoblastoma indicates the location of a new regulatory domain for the RB1 gene.
Oncogene 1996;12(2):431-6.
-
1996: Still I H; Cowell J
The Brn-3a transcription factor gene (POU4F1) maps close to the locus for the variant late infantile form of neuronal ceroid-lipofuscinosis.
Cytogenetics and cell genetics 1996;74(3):225-6.
-
1996: Hawthorn L A; Cowell J K
Regional assignment of EST sequences on human chromosome 13.
Cytogenetics and cell genetics 1996;72(1):72-7.
-
1995: Hawthorn L; Roberts T; Verlind E; Kooy R F; Cowell J K
A yeast artificial chromosome contig that spans the RB1-D13S31 interval on human chromosome 13 and encompasses the frequently deleted region in B-cell chronic lymphocytic leukemia.
Genomics 1995;30(3):425-30.
-
1995: Liu Z; Song Y; Bia B; Cowell J K
Germline mutations in the RB1 gene in patients with hereditary retinoblastoma.
Genes, chromosomes & cancer 1995;14(4):277-84.
-
1995: Bia B; Cowell J K
Independent constitutional germline mutations occurring in the RB1 gene in cousins with bilateral retinoblastoma.
Oncogene 1995;11(5):977-9.
-
1995: Mead R S; Cowell J K
Molecular characterization of a (1;10)(p22;q21) constitutional translocation from a patient with neuroblastoma.
Cancer genetics and cytogenetics 1995;81(2):151-7.
-
1995: Hawthorn L; Cowell J K
Integration of the physical and genetic linkage map for human chromosome 13.
Genomics 1995;27(3):399-404.
-
1995: Kempski H; MacDonald D; Michalski A J; Roberts T; Goldman J M; Cross N C; Cowell J K
Localization of the 8;13 translocation breakpoint associated with myeloproliferative disease to a 1.5 Mbp region of chromosome 13.
Genes, chromosomes & cancer 1995;12(4):283-7.
-
1995: Hellsten E; Vesa J; Heiskanen M; Mäkelä T P; Järvelä I; Cowell J K; Mead S; Alitalo K; Palotie A; Peltonen L
Identification of YAC clones for human chromosome 1p32 and physical mapping of the infantile neuronal ceroid lipofuscinosis (INCL) locus.
Genomics 1995;25(2):404-12.
-
1995: Hawthorn L A; Kapanadse B; Yankovsky N; Cowell J K
Regional localisation of tri- and tetranucleotide repeat sequence-containing cosmids on chromosome 13.
Cytogenetics and cell genetics 1995;70(1-2):102-3.
-
1994: Cotter F E; Johnson P; Hall P; Pocock C; al Mahdi N; Cowell J K; Morgan G
Antisense oligonucleotides suppress B-cell lymphoma growth in a SCID-hu mouse model.
Oncogene 1994;9(10):3049-55.
-
1994: Cowell J K
Genetics of paediatric solid tumours.
British medical bulletin 1994;50(3):600-23.
-
1994: Baird P N; Pritchard J; Cowell J K
Molecular genetic analysis of chromosome 11p in familial Wilms tumour.
British journal of cancer 1994;69(6):1072-7.
-
1994: Kratzke R A; Otterson G A; Hogg A; Coxon A B; Geradts J; Cowell J K; Kaye F J
Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors.
Oncogene 1994;9(5):1321-6.
-
1994: Hawthorn L; Nizetic D; Lehrach H; Cowell J K
Assignment of 55 novel cosmids to seven subregions of chromosome 13 using fluorescence in situ hybridization.
Genomics 1994;21(1):248-50.
-
1994: Chapman R M; Corcoran M M; Gardiner A; Hawthorn L A; Cowell J K; Oscier D G
Frequent homozygous deletions of the D13S25 locus in chromosome region 13q14 defines the location of a gene critical in leukaemogenesis in chronic B-cell lymphocytic leukaemia.
Oncogene 1994;9(4):1289-93.
-
1994: Cowell J K; Jaju R; Kempski H
Isolation and characterisation of a panel of cosmids which allows unequivocal identification of chromosome deletions involving the RB1 gene using fluorescence in situ hybridisation.
Journal of medical genetics 1994;31(4):334-7.
-
1994: Vesa J; Hellsten E; Barnoski B L; Emanuel B S; Billheimer J T; Mead S; Cowell J K; Strauss J F; Peltonen L
Assignment of sterol carrier protein X/sterol carrier protein 2 to 1p32 and its exclusion as the causative gene for infantile neuronal ceroid lipofuscinosis.
Human molecular genetics 1994;3(2):341-6.
-
1994: Michalski A J; Cowell J K
Constructing a physical map around a constitutional t(1;13)(q22;q12) breakpoint in a patient with a ganglioneuroblastoma.
Progress in clinical and biological research 1994;385():79-85.
-
1994: Kooy R F; Verlind E; Houwen R H; Shapiro D N; Hawthorn L A; Cowell J K; Scheffer H; Buys C H
A deletion hybrid breakpoint map of the chromosomal region 13q14-q21 orders 19 genetic markers in 10 intervals.
European journal of human genetics : EJHG 1994;2(1):59-65.
-
1994: Cowell J K; Smith T; Bia B
Frequent constitutional C to T mutations in CGA-arginine codons in the RB1 gene produce premature stop codons in patients with bilateral (hereditary) retinoblastoma.
European journal of human genetics : EJHG 1994;2(4):281-90.
-
1993: Baird P N; Cowell J K
A novel zinc finger mutation in a patient with Denys-Drash syndrome.
Human molecular genetics 1993;2(12):2193-4.
-
1993: Davis A; Cowell J K
Mutations in the PAX6 gene in patients with hereditary aniridia.
Human molecular genetics 1993;2(12):2093-7.
-
1993: Onadim Z; Hogg A; Cowell J K
Mechanisms of oncogenesis in patients with familial retinoblastoma.
British journal of cancer 1993;68(5):958-64.
-
1993: Michalski A J; Cowell J K
Assignment of four sequence-tagged sites to three subregions of 13q12 using a somatic cell hybrid mapping panel.
Genomics 1993;18(1):141-3.
-
1993: Santos A; Osorio-Almeida L; Baird P N; Silva J M; Boavida M G; Cowell J
Insertional inactivation of the WT1 gene in tumour cells from a patient with WAGR syndrome.
Human genetics 1993;92(1):83-6.
-
1993: Hogg A; Bia B; Onadim Z; Cowell J K
Molecular mechanisms of oncogenic mutations in tumors from patients with bilateral and unilateral retinoblastoma.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):7351-5.
-
1993: Hawthorn L A; Chapman R; Oscier D; Cowell J K
The consistent 13q14 translocation breakpoint seen in chronic B-cell leukaemia (BCLL) involves deletion of the D13S25 locus which lies distal to the retinoblastoma predisposition gene.
Oncogene 1993;8(6):1415-9.
-
1993: Cowell J K; Groves N; Baird P
Loss of heterozygosity at 11p13 in Wilms' tumours does not necessarily involve mutations in the WT1 gene.
British journal of cancer 1993;67(6):1259-61.
-
1993: Morris J A; Cowell J K; Stiller C A; Barratt A
Retinoblastoma: a possible link with low level radiation.
Journal of medical genetics 1993;30(5):440-2.
-
1992: Groves N; Baird P N; Hogg A; Cowell J K
A single base pair polymorphism in the WT1 gene detected by single-strand conformation polymorphism analysis.
Human genetics 1992;90(4):440-2.
-
1992: Cowell J K; Hogg A
Genetics and cytogenetics of retinoblastoma.
Cancer genetics and cytogenetics 1992;64(1):1-11.
-
1992: Cowell J K
Tumour suppressor genes.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1992;3(9):693-8.
-
1992: Baird P N; Groves N; Haber D A; Housman D E; Cowell J K
Identification of mutations in the WT1 gene in tumours from patients with the WAGR syndrome.
Oncogene 1992;7(11):2141-9.
-
1992: Lemoine N R; Hughes C M; Cowell J K
Aberrant expression of the tumour suppressor gene p53 is very frequent in Wilms' tumours.
The Journal of pathology 1992;168(2):237-42.
-
1992: Michalski A J; Cotter F E; Cowell J K
Isolation of chromosome-specific DNA sequences from an Alu polymerase chain reaction library to define the breakpoint in a patient with a constitutional translocation t(1;13) (q22;q12) and ganglioneuroblastoma.
Oncogene 1992;7(8):1595-602.
-
1992: Baird P N; Santos A; Groves N; Jadresic L; Cowell J K
Constitutional mutations in the WT1 gene in patients with Denys-Drash syndrome.
Human molecular genetics 1992;1(5):301-5.
-
1992: Onadim Z; Hogg A; Baird P N; Cowell J K
Oncogenic point mutations in exon 20 of the RB1 gene in families showing incomplete penetrance and mild expression of the retinoblastoma phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(13):6177-81.
-
1992: Hogg A; Onadim Z; Baird P N; Cowell J K
Detection of heterozygous mutations in the RB1 gene in retinoblastoma patients using single-strand conformation polymorphism analysis and polymerase chain reaction sequencing.
Oncogene 1992;7(7):1445-51.
-
1992: Onadim Z; Hungerford J; Cowell J K
Follow-up of retinoblastoma patients having prenatal and perinatal predictions for mutant gene carrier status using intragenic polymorphic probes from the RB1 gene.
British journal of cancer 1992;65(5):711-6.
-
1991: Baird P; Wadey R; Cowell J
Loss of heterozygosity for chromosome region 11p15 in Wilms' tumours is not related to HRAS gene transforming mutations.
Oncogene 1991;6(7):1147-9.
-
1991: Cowell J K
Genetic counseling in retinoblastoma.
The British journal of ophthalmology 1991;75(7):447.
-
1991: Onadim Z; Cowell J K
Application of PCR amplification of DNA from paraffin embedded tissue sections to linkage analysis in familial retinoblastoma.
Journal of medical genetics 1991;28(5):312-6.
-
1991: Cowell J K; Wadey R B; Haber D A; Call K M; Housman D E; Pritchard J
Structural rearrangements of the WT1 gene in Wilms' tumour cells.
Oncogene 1991;6(4):595-9.
-
1991: Onadim Z; Hykin P G; Hungerford J L; Cowell J K
Genetic counselling in retinoblastoma: importance of ocular fundus examination of first degree relatives and linkage analysis.
The British journal of ophthalmology 1991;75(3):147-50.
-
1991: Cowell J K
The genetics of retinoblastoma.
British journal of cancer 1991;63(3):333-6.
-
1991: Jadresic L; Wadey R B; Buckle B; Barratt T M; Mitchell C D; Cowell J K
Molecular analysis of chromosome region 11p13 in patients with Drash syndrome.
Human genetics 1991;86(5):497-501.
-
1991: Mitchell C D; Ventris J A; Warr T J; Cowell J K
Molecular definition in a somatic cell hybrid of a specific 2:13 translocation breakpoint in childhood rhabdomyosarcoma.
Oncogene 1991;6(1):89-92.
-
1991: Houwen R H; Pautler S E; Barwell J A; Arden K; Buchanan J A; James C D; Cavenee W K; Buys C H; Cowell J K; Cox D W
Isolation and regional localization of 25 anonymous DNA probes on a chromosome 13 hybrid panel.
Cytogenetics and cell genetics 1991;57(2-3):87-90.
-
1990: Cowell J K
The nuclear oncoproteins: RB and p53.
Seminars in cancer biology 1990;1(6):437-46.
-
1990: Pal N; Wadey R B; Buckle B; Yeomans E; Pritchard J; Cowell J K
Preferential loss of maternal alleles in sporadic Wilms' tumour.
Oncogene 1990;5(11):1665-8.
-
1990: Onadim Z O; Mitchell C D; Rutland P C; Buckle B G; Jay M; Hungerford J L; Harper K; Cowell J K
Application of intragenic DNA probes in prenatal screening for retinoblastoma gene carriers in the United Kingdom.
Archives of disease in childhood 1990;65(7 Spec No):651-6.
-
1990: Wadey R B; Pal N; Buckle B; Yeomans E; Pritchard J; Cowell J K
Loss of heterozygosity in Wilms' tumour involves two distinct regions of chromosome 11.
Oncogene 1990;5(6):901-7.
-
1990: Cowell J K; Onadim Z
Carrier detection and prenatal screening of the retinoblastoma gene.
The Journal of pathology 1990;161(1):3-5.
-
1990: Wadey R B; Little P F; Pritchard J; Cowell J K
Isolation and regional localisation of DNA sequences from a human chromosome 11-specific cosmid library.
Human genetics 1990;84(5):417-23.
-
1989: Spurr N K; Mitchell C; Gough A C; Rooke L; Cowell J K
Assignment of an anonymous DNA sequence IB/D22 (DXS371) to XP11.1-11.4.
Disease markers 1989;7(4):247-51.
-
1989: Edwards Y; West L; Van Heyningen V; Cowell J; Goldberg E
Regional localization of the sperm-specific lactate dehydrogenase, LDHC, gene on human chromosome 11.
Annals of human genetics 1989;53(Pt 3):215-9.
-
1989: Jay M; Cowell J K; Kingston J E; Hungerford J
Demonstration of bias in series of retinoblastoma.
Ophthalmic paediatrics and genetics 1989;10(2):89-92.
-
1989: Cowell J K; Hungerford J; Rutland P; Jay M
Genetic and cytogenetic analysis of patients showing reduced esterase-D levels and mental retardation from a survey of 500 individuals with retinoblastoma.
Ophthalmic paediatrics and genetics 1989;10(2):117-27.
-
1989: Cowell J K
One hundred years of retinoblastoma research. From the clinic to the gene and back again.
Ophthalmic paediatrics and genetics 1989;10(2):75-88.
-
1989: Cowell J K; Wadey R B; Buckle B B; Pritchard J
The aniridia-Wilms' tumour association: molecular and genetic analysis of chromosome deletions on the short arm of chromosome 11.
Human genetics 1989;82(2):123-6.
-
1989: Wadey R B; Cowell J K
A MspI RFLP associated with the human catalase gene.
Nucleic acids research 1989;17(8):3332.
-
1989: Mitchell C D; Cowell J K
Predisposition to retinoblastoma due to a translocation within the 4.7R locus.
Oncogene 1989;4(2):253-7.
-
1989: Cowell J K; Mitchell C D
A somatic cell hybrid mapping panel for regional assignment of human chromosome 13 DNA sequences.
Cytogenetics and cell genetics 1989;52(1-2):1-6.
-
1988: Mitchell C D; Cowell J K
Molecular evidence that the esterase-D gene lies proximal to the retinoblastoma susceptibility locus in chromosome region 13q14.
Human genetics 1988;81(1):57-60.
-
1988: Boehm T; Lavenir I; Forster A; Wadey R B; Cowell J K; Harbott J; Lampert F; Waters J; Sherrington P; Couillin P
The T-ALL specific t(11;14)(p13;q11) translocation breakpoint cluster region is located near to the Wilms' tumour predisposition locus.
Oncogene 1988;3(6):691-5.
-
1988: Cowell J K; Rutland P; Hungerford J; Jay M
Deletion of chromosome region 13q14 is transmissible and does not always predispose to retinoblastoma.
Human genetics 1988;80(1):43-5.
-
1988: Solis V; Pritchard J; Cowell J K
Cytogenetic changes in Wilms' tumors.
Cancer genetics and cytogenetics 1988;34(2):223-34.
-
1988: Lewis W H; Yeger H; Bonetta L; Chan H S; Kang J; Junien C; Cowell J; Jones C; Dafoe L A
Homozygous deletion of a DNA marker from chromosome 11p13 in sporadic Wilms tumor.
Genomics 1988;3(1):25-31.
-
1988: Ades A E; Garrett A J; Cowell J; Chin K S; Peckham C S
Computer matching of oligonucleotide patterns on electrophoretic gels: an application to the epidemiology of cytomegalovirus.
Epidemiology and infection 1988;100(3):467-79.
-
1988: Cowell J K; Hungerford J; Jay M; Rutland P
Retinoblastoma--clinical and genetic aspects: a review.
Journal of the Royal Society of Medicine 1988;81(4):220-3.
-
1988: Mitchell C; Nicolaides K; Kingston J; Hungerford J; Jay M; Cowell J
Prenatal exclusion of hereditary retinoblastoma.
Lancet 1988;1(8589):826.
-
1988: Jay M; Cowell J; Hungerford J
Register of retinoblastoma: preliminary results.
Eye (London, England) 1988;2 ( Pt 1)():102-5.
-
1987: Cowell J K; Hungerford J; Rutland P; Jay M
A chromosomal breakpoint that separates the esterase D and retinoblastoma predisposition loci in a patient with del(13)(q14q31).
Cancer genetics and cytogenetics 1987;27(1):27-31.
-
1987: Cowell J K; Jay M; Rutland P; Hungerford J
An assessment of the usefulness of electrophoretic variants of esterase-D in the antenatal diagnosis of retinoblastoma in the United Kingdom.
British journal of cancer 1987;55(6):661-4.
-
1987: Cowell J K; Thompson E; Rutland P
The need to screen all retinoblastoma patients for esterase D activity: detection of submicroscopic chromosome deletions.
Archives of disease in childhood 1987;62(1):8-11.
-
1987: Cowell J; Pritchard J
The molecular genetics of retinoblastoma and Wilms' tumor.
Critical reviews in oncology/hematology 1987;7(2):153-68.
-
1986: Cowell J K; Rutland P; Jay M; Hungerford J
Effect of the esterase-D phenotype on its in vitro enzyme activity.
Human genetics 1986;74(3):298-301.
-
1986: Cowell J K; Rutland P; Jay M; Hungerford J
Deletions of the esterase D locus from a survey of 200 retinoblastoma patients.
Human genetics 1986;72(2):164-7.
-
1986: Brook J D; Shaw D J; Thomas N S; Meredith A L; Cowell J; Harper P S
Mapping genetic markers on human chromosome 19 using subchromosomal fragments in somatic cell hybrids.
Cytogenetics and cell genetics 1986;41(1):30-7.
-
1985: Phillips I R; Shephard E A; Povey S; Davis M B; Kelsey G; Monteiro M; West L F; Cowell J
A cytochrome P-450 gene family mapped to human chromosome 19.
Annals of human genetics 1985;49(Pt 4):267-74.
-
1985: Scott J; Cowell J; Robertson M E; Priestley L M; Wadey R; Hopkins B; Pritchard J; Bell G I; Rall L B; Graham C F
Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues.
Nature 1985;317(6034):260-2.
-
1984: Wigley C B; Cowell J K
Presence of two cytogenetic forms of amplified DNA: evidence for a role in tumor growth in an intraspecific mouse hybrid cell line.
Journal of the National Cancer Institute 1984;73(1):219-26.
-
1984: Cowell J K; Franks L M
The ability of normal mouse cells to reduce the malignant potential of transformed mouse bladder epithelial cells depends on their somatic origin.
International journal of cancer. Journal international du cancer 1984;33(5):657-67.
-
1984: Cowell J K
A photographic representation of the variability in the G-banded structure of the chromosomes in the mouse karyotype. A guide to the identification of the individual chromosomes.
Chromosoma 1984;89(4):294-320.
-
1983: Cowell J K; Rupniak H T
Chromosome analysis of human neuroblastoma cell line TR14 showing double minutes and an aberration involving chromosome 1.
Cancer genetics and cytogenetics 1983;9(3):273-80.
-
1983: Cowell J K; Miller O J
Occurrence and evolution of homogeneously staining regions may be due to breakage-fusion-bridge cycles following telomere loss.
Chromosoma 1983;88(3):216-21.
-
1982: Cowell J K; Wigley C B
Chromosome changes associated with the progression of cell lines from preneoplastic to tumorigenic phenotype during transformation of mouse salivary gland epithelium in vitro.
Journal of the National Cancer Institute 1982;69(2):425-33.
-
1982: Cowell J K
Appearance of double minute chromosomes in somatic cell hybridisation experiments involving the HAT selection system.
Cell biology international reports 1982;6(4):393-9.
-
1982: Cowell J K
Double minutes and homogeneously staining regions: gene amplification in mammalian cells.
Annual review of genetics 1982;16():21-59.
-
1981: Cowell J K
Evolution of a normal karyotype in a mouse bladder epithelial cell line transformed in vitro.
Cancer genetics and cytogenetics 1981;3(4):359-61.
-
1981: Cowell J K
Chromosome abnormalities associated with salivary gland epithelial cell lines transformed in vitro and in vivo with evidence of a role for genetic imbalance in transformation.
Cancer research 1981;41(4):1508-17.
-
1980: Cowell J K
Consistent chromosome abnormalities associated with mouse bladder epithelial cell lines transformed in vitro.
Journal of the National Cancer Institute 1980;65(5):955-61.
-
1980: Cowell J K; Wigley C B
Changes in DNA content during in vitro transformation of mouse salivary gland epithelium.
Journal of the National Cancer Institute 1980;64(6):1443-9.
-
1980: Cowell J K; Franks L M
A rapid method for accurate DNA measurements in single cells in situ using a simple microfluorimeter and Hoechst 33258 as a quantitative fluorochrome.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1980;28(3):206-10.
-
1980: Cowell J K
A new chromosome region possibly derived from double minutes in an in vitro transformed epithelial cell line.
Cytogenetics and cell genetics 1980;27(1):2-7.
-
1980: Cowell J K; Hartmann-Goldstein I J
Modification of the DNA content in translocated regions of Drosophila polytene chromosomes.
Chromosoma 1980;81(1):55-64.
-
1980: Cowell J K; Hartmann-Goldstein I J
Contrasting response of euchromatin and heterochromatin to translocation in polytene chromosomes of Drosophila melanogaster.
Chromosoma 1980;79(3):329-40.
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