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David Klein
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34
Coon, Steven
29
Weller, Joan
14
Roseboom, PH
14
Ganguly, Surajit
12
Møller, Morten
11
Baler, Ruben
10
Falcón, Jack
10
Iuvone, Michael
7
Gothilf, Yoav
7
Rath, Martin
6
Gaildrat, Pascaline
6
Gastel, JA
6
Dyda, Fred
6
Hickman, Alison Burgess
5
Haque, Rashidul
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All Publications
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2009: Alon Shahar; Eisenberg Eli; Jacob-Hirsch Jasmine; Rechavi Gideon; Vatine Gad; Toyama Reiko; Coon Steven L; Klein David C; Gothilf Yoav
A new cis-acting regulatory element driving gene expression in the zebrafish pineal gland.
Bioinformatics (Oxford, England) 2009;25(5):559-62.
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2009: Bailey Michael J; Coon Steven L; Carter David A; Humphries Ann; Kim Jong-So; Shi Qiong; Gaildrat Pascaline; Morin Fabrice; Ganguly Surajit; Hogenesch John B; Weller Joan L; Rath Martin F; Møller Morten; Baler Ruben; Sugden David; Rangel Zoila G; Munson Peter J; Klein David C
Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling.
The Journal of biological chemistry 2009;284(12):7606-22.
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2009: Rath Martin F; Bailey Michael J; Kim Jong-So; Ho Anthony K; Gaildrat Pascaline; Coon Steven L; Møller Morten; Klein David C
Developmental and diurnal dynamics of Pax4 expression in the mammalian pineal gland: nocturnal down-regulation is mediated by adrenergic-cyclic adenosine 3',5'-monophosphate signaling.
Endocrinology 2009;150(2):803-11.
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2009: Rath Martin F; Bailey Michael J; Kim Jong-So; Coon Steven L; Klein David C; Møller Morten
Developmental and daily expression of the Pax4 and Pax6 homeobox genes in the rat retina: localization of Pax4 in photoreceptor cells.
Journal of neurochemistry 2009;108(1):285-94.
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2008: Klitten Laura L; Rath Martin F; Coon Steven L; Kim Jong-So; Klein David C; Møller Morten
Localization and regulation of dopamine receptor D4 expression in the adult and developing rat retina.
Experimental eye research 2008;87(5):471-7.
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2008: Pavlicek Jiri; Coon Steven L; Ganguly Surajit; Weller Joan L; Hassan Sergio A; Sackett Dan L; Klein David C
Evidence that proline focuses movement of the floppy loop of arylalkylamine N-acetyltransferase (EC 2.3.1.87).
The Journal of biological chemistry 2008;283(21):14552-8.
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2007: Szewczuk Lawrence M; Saldanha S Adrian; Ganguly Surajit; Bowers Erin M; Javoroncov Margarita; Karanam Balasubramanyam; Culhane Jeffrey C; Holbert Marc A; Klein David C; Abagyan Ruben; Cole Philip A
De novo discovery of serotonin N-acetyltransferase inhibitors.
Journal of medicinal chemistry 2007;50(22):5330-8.
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2007: Ganguly Surajit; Grodzki Cristina; Sugden David; Møller Morten; Odom Sandra; Gaildrat Pascaline; Gery Igal; Siraganian Reuben P; Rivera Juan; Klein David C
Neural adrenergic/cyclic AMP regulation of the immunoglobulin E receptor alpha-subunit expression in the mammalian pinealocyte: a neuroendocrine/immune response link?
The Journal of biological chemistry 2007;282(45):32758-64.
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2007: Muñoz Estela M; Bailey Michael J; Rath Martin F; Shi Qiong; Morin Fabrice; Coon Steven L; Møller Morten; Klein David C
NeuroD1: developmental expression and regulated genes in the rodent pineal gland.
Journal of neurochemistry 2007;102(3):887-99.
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2007: Latz Eicke; Verma Anjali; Visintin Alberto; Gong Mei; Sirois Cherilyn M; Klein Dionne C G; Monks Brian G; McKnight C James; Lamphier Marc S; Duprex W Paul; Espevik Terje; Golenbock Douglas T
Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Nature immunology 2007;8(7):772-9.
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2007: Rath Martin F; Morin Fabrice; Shi Qiong; Klein David C; Møller Morten
Ontogenetic expression of the Otx2 and Crx homeobox genes in the retina of the rat.
Experimental eye research 2007;85(1):65-73.
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2007: Humphries Ann; Wells Tim; Baler Ruben; Klein David C; Carter David A
Rodent Aanat: intronic E-box sequences control tissue specificity but not rhythmic expression in the pineal gland.
Molecular and cellular endocrinology 2007;270(1-2):43-9.
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2007: Klein David C
The pineal gene expression party: who's the surprise guest?
Endocrinology 2007;148(4):1463-4.
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2007: Kim Jong-So; Bailey Michael J; Ho Anthony K; Møller Morten; Gaildrat Pascaline; Klein David C
Daily rhythm in pineal phosphodiesterase (PDE) activity reflects adrenergic/3',5'-cyclic adenosine 5'-monophosphate induction of the PDE4B2 variant.
Endocrinology 2007;148(4):1475-85.
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2007: Hwang Yousang; Ganguly Surajit; Ho Anthony K; Klein David C; Cole Philip A
Enzymatic and cellular study of a serotonin N-acetyltransferase phosphopantetheine-based prodrug.
Bioorganic & medicinal chemistry 2007;15(5):2147-55.
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2007: Klein David C
Arylalkylamine N-acetyltransferase: "the Timezyme".
The Journal of biological chemistry 2007;282(7):4233-7.
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2007: Zilberman-Peled B; Appelbaum L; Vallone D; Foulkes N S; Anava S; Anzulovich A; Coon S L; Klein D C; Falcón J; Ron B; Gothilf Y
Transcriptional regulation of arylalkylamine-N-acetyltransferase-2 gene in the pineal gland of the gilthead seabream.
Journal of neuroendocrinology 2007;19(1):46-53.
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2006: Pozdeyev Nikita; Taylor Carla; Haque Rashidul; Chaurasia Shyam S; Visser Amy; Thazyeen Aamera; Du Yuhong; Fu Haian; Weller Joan; Klein David C; Iuvone P Michael
Photic regulation of arylalkylamine N-acetyltransferase binding to 14-3-3 proteins in retinal photoreceptor cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(36):9153-61.
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2006: Coon Steven L; Klein David C
Evolution of arylalkylamine N-acetyltransferase: emergence and divergence.
Molecular and cellular endocrinology 2006;252(1-2):2-10.
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2006: Vuilleumier Robin; Besseau Laurence; Boeuf Gilles; Piparelli Aurélien; Gothilf Yoav; Gehring Walter G; Klein David C; Falcón Jack
Starting the zebrafish pineal circadian clock with a single photic transition.
Endocrinology 2006;147(5):2273-9.
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2006: Rath Martin F; Muñoz Estela; Ganguly Surajit; Morin Fabrice; Shi Qiong; Klein David C; Møller Morten
Expression of the Otx2 homeobox gene in the developing mammalian brain: embryonic and adult expression in the pineal gland.
Journal of neurochemistry 2006;97(2):556-66.
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2006: Besseau Laurence; Benyassi Ahmed; Møller Morten; Coon Steven L; Weller Joan L; Boeuf Gilles; Klein David C; Falcón Jack
Melatonin pathway: breaking the 'high-at-night' rule in trout retina.
Experimental eye research 2006;82(4):620-7.
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2006: Møller Morten; Rath Martin F; Klein David C
The perivascular phagocyte of the mouse pineal gland: an antigen-presenting cell.
Chronobiology international 2006;23(1-2):393-401.
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2006: Klein David C
Evolution of the vertebrate pineal gland: the AANAT hypothesis.
Chronobiology international 2006;23(1-2):5-20.
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2005: Iuvone P Michael; Tosini Gianluca; Pozdeyev Nikita; Haque Rashidul; Klein David C; Chaurasia Shyam S
Circadian clocks, clock networks, arylalkylamine N-acetyltransferase, and melatonin in the retina.
Progress in retinal and eye research 2005;24(4):433-56.
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2005: Gaildrat Pascaline; Møller Morten; Mukda Sujira; Humphries Ann; Carter David A; Ganapathy Vadivel; Klein David C
A novel pineal-specific product of the oligopeptide transporter PepT1 gene: circadian expression mediated by cAMP activation of an intronic promoter.
The Journal of biological chemistry 2005;280(17):16851-60.
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2005: Zheng Weiping; Schwarzer Dirk; Lebeau Aaron; Weller Joan L; Klein David C; Cole Philip A
Cellular stability of serotonin N-acetyltransferase conferred by phosphonodifluoromethylene alanine (Pfa) substitution for Ser-205.
The Journal of biological chemistry 2005;280(11):10462-7.
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2005: Ganguly Surajit; Weller Joan L; Ho Anthony; Chemineau Philippe; Malpaux Benoit; Klein David C
Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(4):1222-7.
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2005: Kim Jong-So; Coon Steven L; Blackshaw Seth; Cepko Constance L; Møller Morten; Mukda Sujira; Zhao Wan-Qian; Charlton Clivel G; Klein David C
Methionine adenosyltransferase:adrenergic-cAMP mechanism regulates a daily rhythm in pineal expression.
The Journal of biological chemistry 2005;280(1):677-84.
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2004: Price Donald M; Chik Constance L; Terriff David; Weller Joan; Humphries Ann; Carter David A; Klein David C; Ho Anthony K
Mitogen-activated protein kinase phosphatase-1 (MKP-1): >100-fold nocturnal and norepinephrine-induced changes in the rat pineal gland.
FEBS letters 2004;577(1-2):220-6.
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2004: Klein David C
The 2004 Aschoff/Pittendrigh lecture: Theory of the origin of the pineal gland--a tale of conflict and resolution.
Journal of biological rhythms 2004;19(4):264-79.
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2004: Iyer Lakshminarayan M; Aravind L; Coon Steven L; Klein David C; Koonin Eugene V
Evolution of cell-cell signaling in animals: did late horizontal gene transfer from bacteria have a role?
Trends in genetics : TIG 2004;20(7):292-9.
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2004: Appelbaum Lior; Toyama Reiko; Dawid Igor B; Klein David C; Baler Ruben; Gothilf Yoav
Zebrafish serotonin-N-acetyltransferase-2 gene regulation: pineal-restrictive downstream module contains a functional E-box and three photoreceptor conserved elements.
Molecular endocrinology (Baltimore, Md.) 2004;18(5):1210-21.
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2003: Klein Dionne C; Stroh Cordula M; Jensenius Henriette; van Es Maarten; Kamruzzahan A S; Stamouli Amalia; Gruber Hermann J; Oosterkamp Tjerk H; Hinterdorfer Peter
Covalent immobilization of single proteins on mica for molecular recognition force microscopy.
Chemphyschem : a European journal of chemical physics and physical chemistry 2003;4(12):1367-71.
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2003: Zheng Weiping; Zhang Zhongsen; Ganguly Surajit; Weller Joan L; Klein David C; Cole Philip A
Cellular stabilization of the melatonin rhythm enzyme induced by nonhydrolyzable phosphonate incorporation.
Nature structural biology 2003;10(12):1054-7.
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2003: Chong Nelson W; Chaurasia Shyam S; Haque Rashidul; Klein David C; Iuvone P Michael
Temporal-spatial characterization of chicken clock genes: circadian expression in retina, pineal gland, and peripheral tissues.
Journal of neurochemistry 2003;85(4):851-60.
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2003: Stamouli Amalia; Kafi Sidig; Klein Dionne C G; Oosterkamp Tjerk H; Frenken Joost W M; Cogdell Richard J; Aartsma Thijs J
The ring structure and organization of light harvesting 2 complexes in a reconstituted lipid bilayer, resolved by atomic force microscopy.
Biophysical journal 2003;84(4):2483-91.
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2003: Falcón J; Gothilf Y; Coon S L; Boeuf G; Klein D C
Genetic, temporal and developmental differences between melatonin rhythm generating systems in the teleost fish pineal organ and retina.
Journal of neuroendocrinology 2003;15(4):378-82.
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2003: Klein D C; Ganguly S; Coon S L; Shi Q; Gaildrat P; Morin F; Weller J L; Obsil T; Hickman A; Dyda F
14-3-3 proteins in pineal photoneuroendocrine transduction: how many roles?
Journal of neuroendocrinology 2003;15(4):370-7.
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2002: Gothilf Yoav; Toyama Reiko; Coon Steven L; Du Shao-Jun; Dawid Igor B; Klein David C
Pineal-specific expression of green fluorescent protein under the control of the serotonin-N-acetyltransferase gene regulatory regions in transgenic zebrafish.
Developmental dynamics : an official publication of the American Association of Anatomists 2002;225(3):241-9.
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2002: Coon Steven L; Del Olmo Elena; Young W Scott; Klein David C
Melatonin synthesis enzymes in Macaca mulatta: focus on arylalkylamine N-acetyltransferase (EC 2.3.1.87).
The Journal of clinical endocrinology and metabolism 2002;87(10):4699-706.
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2002: Schomerus Christof; Laedtke Elke; Olcese James; Weller Joan L; Klein David C; Korf Horst-Werner
Signal transduction and regulation of melatonin synthesis in bovine pinealocytes: impact of adrenergic, peptidergic and cholinergic stimuli.
Cell and tissue research 2002;309(3):417-28.
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2002: Klein D C; Ganguly S; Coon S; Weller J L; Obsil T; Hickman A; Dyda F
14-3-3 Proteins and photoneuroendocrine transduction: role in controlling the daily rhythm in melatonin.
Biochemical Society transactions 2002;30(4):365-73.
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2002: Ganguly Surajit; Coon Steven L; Klein David C
Control of melatonin synthesis in the mammalian pineal gland: the critical role of serotonin acetylation.
Cell and tissue research 2002;309(1):127-37.
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2002: van Hemert Martijn J; Lamers Gerda E M; Klein Dionne C G; Oosterkamp Tjerk H; Steensma H Yde; van Heusden G Paul H
The Saccharomyces cerevisiae Fin1 protein forms cell cycle-specific filaments between spindle pole bodies.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5390-3.
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2002: Iuvone P Michael; Brown Audra D; Haque Rashidul; Weller Joan; Zawilska Jolanta B; Chaurasia Shyam S; Ma Minhui; Klein David C
Retinal melatonin production: role of proteasomal proteolysis in circadian and photic control of arylalkylamine N-acetyltransferase.
Investigative ophthalmology & visual science 2002;43(2):564-72.
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2001: Ganguly S; Mummaneni P; Steinbach P J; Klein D C; Coon S L
Characterization of the Saccharomyces cerevisiae homolog of the melatonin rhythm enzyme arylalkylamine N-acetyltransferase (EC 2.3.1.87).
The Journal of biological chemistry 2001;276(50):47239-47.
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2001: Ganguly S; Gastel J A; Weller J L; Schwartz C; Jaffe H; Namboodiri M A; Coon S L; Hickman A B; Rollag M; Obsil T; Beauverger P; Ferry G; Boutin J A; Klein D C
Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(14):8083-8.
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2001: Coon S L; Weller J L; Korf H W; Namboodiri M A; Rollag M; Klein D C
cAmp regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activation.
The Journal of biological chemistry 2001;276(26):24097-107.
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2001: Falcón J; Galarneau K M; Weller J L; Ron B; Chen G; Coon S L; Klein D C
Regulation of arylalkylamine N-acetyltransferase-2 (AANAT2, EC 2.3.1.87) in the fish pineal organ: evidence for a role of proteasomal proteolysis.
Endocrinology 2001;142(5):1804-13.
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2001: Obsil T; Ghirlando R; Klein D C; Ganguly S; Dyda F
Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation.
Cell 2001;105(2):257-67.
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2000: Schomerus C; Korf H W; Laedtke E; Weller J L; Klein D C
Selective adrenergic/cyclic AMP-dependent switch-off of proteasomal proteolysis alone switches on neural signal transduction: an example from the pineal gland.
Journal of neurochemistry 2000;75(5):2123-32.
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2000: Chong N W; Bernard M; Klein D C
Characterization of the chicken serotonin N-acetyltransferase gene. Activation via clock gene heterodimer/E box interaction.
The Journal of biological chemistry 2000;275(42):32991-8.
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2000: Zatz M; Gastel J A; Heath J R; Klein D C
Chick pineal melatonin synthesis: light and cyclic AMP control abundance of serotonin N-acetyltransferase protein.
Journal of neurochemistry 2000;74(6):2315-21.
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2000: Benyassi A; Schwartz C; Coon S L; Klein D C; Falcón J
Melatonin synthesis: arylalkylamine N-acetyltransferases in trout retina and pineal organ are different.
Neuroreport 2000;11(2):255-8.
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2000: Dyda F; Klein D C; Hickman A B
GCN5-related N-acetyltransferases: a structural overview.
Annual review of biophysics and biomolecular structure 2000;29():81-103.
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2000: Schwartz W J; Carpino A; de la Iglesia H O; Baler R; Klein D C; Nakabeppu Y; Aronin N
Differential regulation of fos family genes in the ventrolateral and dorsomedial subdivisions of the rat suprachiasmatic nucleus.
Neuroscience 2000;98(3):535-47.
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1999: Baler R; Covington S; Klein D C
Rat arylalkylamine N-acetyltransferase gene: upstream and intronic components of a bipartite promoter.
Biology of the cell / under the auspices of the European Cell Biology Organization 1999;91(9):699-705.
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1999: Coon S L; Zarazaga L A; Malpaux B; Ravault J P; Bodin L; Voisin P; Weller J L; Klein D C; Chemineau P
Genetic variability in plasma melatonin in sheep is due to pineal weight, not to variations in enzyme activities.
The American journal of physiology 1999;277(5 Pt 1):E792-7.
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1999: Grève P; Alonso-Gómez A; Bernard M; Ma M; Haque R; Klein D C; Iuvone P M
Serotonin N-acetyltransferase mRNA levels in photoreceptor-enriched chicken retinal cell cultures: elevation by cyclic AMP.
Journal of neurochemistry 1999;73(5):1894-900.
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1999: Gothilf Y; Coon S L; Toyama R; Chitnis A; Namboodiri M A; Klein D C
Zebrafish serotonin N-acetyltransferase-2: marker for development of pineal photoreceptors and circadian clock function.
Endocrinology 1999;140(10):4895-903.
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1999: Bernard M; Guerlotté J; Grève P; Gréchez-Cassiau A; Iuvone M P; Zatz M; Chong N W; Klein D C; Voisin P
Melatonin synthesis pathway: circadian regulation of the genes encoding the key enzymes in the chicken pineal gland and retina.
Reproduction, nutrition, development 1999;39(3):325-34.
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1999: Hickman A B; Namboodiri M A; Klein D C; Dyda F
The structural basis of ordered substrate binding by serotonin N-acetyltransferase: enzyme complex at 1.8 A resolution with a bisubstrate analog.
Cell 1999;97(3):361-9.
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1999: Coon S L; Bégay V; Deurloo D; Falcón J; Klein D C
Two arylalkylamine N-acetyltransferase genes mediate melatonin synthesis in fish.
The Journal of biological chemistry 1999;274(13):9076-82.
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1999: Fleming J V; Barrett P; Coon S L; Klein D C; Morgan P J
Ovine arylalkylamine N-acetyltransferase in the pineal and pituitary glands: differences in function and regulation.
Endocrinology 1999;140(2):972-8.
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1999: Hickman A B; Klein D C; Dyda F
Melatonin biosynthesis: the structure of serotonin N-acetyltransferase at 2.5 A resolution suggests a catalytic mechanism.
Molecular cell 1999;3(1):23-32.
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1999: Iuvone P M; Chong N W; Bernard M; Brown A D; Thomas K B; Klein D C
Melatonin biosynthesis in chicken retina. Regulation of tryptophan hydroxylase and arylalkylamine N-acetyltransferase.
Advances in experimental medicine and biology 1999;460():31-41.
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1999: Klein D C
Serotonin N-acetyltransferase. A personal historical perspective.
Advances in experimental medicine and biology 1999;460():5-16.
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1998: Roseboom P H; Namboodiri M A; Zimonjic D B; Popescu N C; Rodriguez I R; Gastel J A; Klein D C
Natural melatonin 'knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase.
Brain research. Molecular brain research 1998;63(1):189-97.
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1998: Chong N W; Cassone V M; Bernard M; Klein D C; Iuvone P M
Circadian expression of tryptophan hydroxylase mRNA in the chicken retina.
Brain research. Molecular brain research 1998;61(1-2):243-50.
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1998: Coon S L; Bégay V; Falcón J; Klein D C
Expression of melatonin synthesis genes is controlled by a circadian clock in the pike pineal organ but not in the trout.
Biology of the cell / under the auspices of the European Cell Biology Organization 1998;90(5):399-405.
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1998: Bégay V; Falcón J; Cahill G M; Klein D C; Coon S L
Transcripts encoding two melatonin synthesis enzymes in the teleost pineal organ: circadian regulation in pike and zebrafish, but not in trout.
Endocrinology 1998;139(3):905-12.
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1998: Gastel J A; Roseboom P H; Rinaldi P A; Weller J L; Klein D C
Melatonin production: proteasomal proteolysis in serotonin N-acetyltransferase regulation.
Science (New York, N.Y.) 1998;279(5355):1358-60.
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1998: De Angelis J; Gastel J; Klein D C; Cole P A
Kinetic analysis of the catalytic mechanism of serotonin N-acetyltransferase (EC 2.3.1.87).
The Journal of biological chemistry 1998;273(5):3045-50.
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1997: Iuvone P M; Bernard M; Alonso-Gomez A; Greve P; Cassone V M; Klein D C
Cellular and molecular regulation of serotonin N-acetyltransferase activity in chicken retinal photoreceptors.
Biological signals 1997;6(4-6):217-24.
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1997: Coon S L; McCune S K; Sugden D; Klein D C
Regulation of pineal alpha1B-adrenergic receptor mRNA: day/night rhythm and beta-adrenergic receptor/cyclic AMP control.
Molecular pharmacology 1997;51(4):551-7.
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1997: Baler R; Covington S; Klein D C
The rat arylalkylamine N-acetyltransferase gene promoter. cAMP activation via a cAMP-responsive element-CCAAT complex.
The Journal of biological chemistry 1997;272(11):6979-85.
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1997: Chik C L; Liu Q Y; Li B; Klein D C; Zylka M; Kim D S; Chin H; Karpinski E; Ho A K
Alpha 1D L-type Ca(2+)-channel currents: inhibition by a beta-adrenergic agonist and pituitary adenylate cyclase-activating polypeptide (PACAP) in rat pinealocytes.
Journal of neurochemistry 1997;68(3):1078-87.
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1997: Bernard M; Klein D C; Zatz M
Chick pineal clock regulates serotonin N-acetyltransferase mRNA rhythm in culture.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(1):304-9.
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1997: Bernard M; Iuvone P M; Cassone V M; Roseboom P H; Coon S L; Klein D C
Avian melatonin synthesis: photic and circadian regulation of serotonin N-acetyltransferase mRNA in the chicken pineal gland and retina.
Journal of neurochemistry 1997;68(1):213-24.
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1997: Klein D C; Coon S L; Roseboom P H; Weller J L; Bernard M; Gastel J A; Zatz M; Iuvone P M; Rodriguez I R; Bégay V; Falcón J; Cahill G M; Cassone V M; Baler R
The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland.
Recent progress in hormone research 1997;52():307-57; discussion 357-8.
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1996: Bernard M; Klein D C
Retinoic acid increases hydroxyindole-O-methyltransferase activity and mRNA in human Y-79 retinoblastoma cells.
Journal of neurochemistry 1996;67(3):1032-8.
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1996: Bernard M; Voisin P; Klein D C
Hydroxyindole-O-methyltransferase in Y-79 cells: regulation by serum.
Brain research 1996;727(1-2):118-24.
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1996: Sugden D; Anwar N; Klein D C
Rat pineal alpha 1-adrenoceptor subtypes: studies using radioligand binding and reverse transcription-polymerase chain reaction analysis.
British journal of pharmacology 1996;118(5):1246-52.
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1996: Roseboom P H; Coon S L; Baler R; McCune S K; Weller J L; Klein D C
Melatonin synthesis: analysis of the more than 150-fold nocturnal increase in serotonin N-acetyltransferase messenger ribonucleic acid in the rat pineal gland.
Endocrinology 1996;137(7):3033-45.
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1996: Coon S L; Mazuruk K; Bernard M; Roseboom P H; Klein D C; Rodriguez I R
The human serotonin N-acetyltransferase (EC 2.3.1.87) gene (AANAT): structure, chromosomal localization, and tissue expression.
Genomics 1996;34(1):76-84.
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1996: Klein D C; Roseboom P H; Coon S L
New light is shining on the melatonin rhythm enzyme The first postcloning view.
Trends in endocrinology and metabolism: TEM 1996;7(3):106-12.
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1996: Weller J L; Jaffe H; Roseboom P H; Zylka M J; Klein D C
2D-PAGE analysis: adrenergically regulated pineal protein AIP 37/6 is a phosphorylated isoform of cytosolic malate dehydrogenase.
Brain research 1996;713(1-2):8-16.
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1996: Baler R; Coon S; Klein D C
Orphan nuclear receptor RZRbeta: cyclic AMP regulates expression in the pineal gland.
Biochemical and biophysical research communications 1996;220(3):975-8.
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1995: Coon S L; Roseboom P H; Baler R; Weller J L; Namboodiri M A; Koonin E V; Klein D C
Pineal serotonin N-acetyltransferase: expression cloning and molecular analysis.
Science (New York, N.Y.) 1995;270(5242):1681-3.
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1995: Baler R; Klein D C
Circadian expression of transcription factor Fra-2 in the rat pineal gland.
The Journal of biological chemistry 1995;270(45):27319-25.
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1995: Bernard M; Donohue S J; Klein D C
Human hydroxyindole-O-methyltransferase in pineal gland, retina and Y79 retinoblastoma cells.
Brain research 1995;696(1-2):37-48.
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1995: Vanecek J; Klein D C
Mechanism of melatonin signal transduction in the neonatal rat pituitary.
Neurochemistry international 1995;27(3):273-8.
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1995: Vanecek J; Klein D C
Melatonin inhibition of GnRH-induced LH release from neonatal rat gonadotroph: involvement of Ca2+ not cAMP.
The American journal of physiology 1995;269(1 Pt 1):E85-90.
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1995: Schaad N C; Vanecek J; Rodriguez I R; Klein D C; Holtzclaw L; Russell J T
Vasoactive intestinal peptide elevates pinealocyte intracellular calcium concentrations by enhancing influx: evidence for involvement of a cyclic GMP-dependent mechanism.
Molecular pharmacology 1995;47(5):923-33.
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1995: Roseboom P H; Klein D C
Norepinephrine stimulation of pineal cyclic AMP response element-binding protein phosphorylation: primary role of a beta-adrenergic receptor/cyclic AMP mechanism.
Molecular pharmacology 1995;47(3):439-49.
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1995: White B H; Klein D C
Stimulation of cyclic GMP accumulation by sodium nitroprusside is potentiated via a Gs mechanism in intact pinealocytes.
Journal of neurochemistry 1995;64(2):711-7.
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1994: Lin A M; Schaad N C; Schulz P E; Coon S L; Klein D C
Pineal nitric oxide synthase: characteristics, adrenergic regulation and function.
Brain research 1994;651(1-2):160-8.
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1994: Roseboom P H; Weller J L; Babila T; Aitken A; Sellers L A; Moffett J R; Namboodiri M A; Klein D C
Cloning and characterization of the epsilon and zeta isoforms of the 14-3-3 proteins.
DNA and cell biology 1994;13(6):629-40.
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1994: Babila T; Klein D C
Cholera toxin-induced Gs alpha down-regulation in neural tissue: studies on the pineal gland.
Brain research 1994;638(1-2):151-6.
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1993: Donohue S J; Roseboom P H; Illnerova H; Weller J L; Klein D C
Human hydroxyindole-O-methyltransferase: presence of LINE-1 fragment in a cDNA clone and pineal mRNA.
DNA and cell biology 1993;12(8):715-27.
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1993: Vanecek J; Klein D C
A subpopulation of neonatal gonadotropin-releasing hormone-sensitive pituitary cells is responsive to melatonin.
Endocrinology 1993;133(1):360-7.
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1993: Schaad N C; Parfitt A; Russell J T; Schaffner A E; Korf H W; Klein D C
Single-cell [Ca2+]i analysis and biochemical characterization of pinealocytes immobilized with novel attachment peptide preparation.
Brain research 1993;614(1-2):251-6.
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1993: Slim R; Le Paslier D; Compain S; Levilliers J; Ougen P; Billault A; Donohue S J; Klein D C; Mintz L; Bernheim A
Construction of a yeast artificial chromosome contig spanning the pseudoautosomal region and isolation of 25 new sequence-tagged sites.
Genomics 1993;16(3):691-7.
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1993: Yu L; Schaad N C; Klein D C
Calcium potentiates cyclic AMP stimulation of pineal arylalkylamine N-acetyltransferase.
Journal of neurochemistry 1993;60(4):1436-43.
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1993: White B H; Klein D C
Developmental appearance of pineal adrenergic-->guanosine 3',5'-monophosphate response is determined by a process down-stream from elevation of intracellular Ca2+: possible involvement of a diffusible factor.
Endocrinology 1993;132(3):1026-34.
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1993: Yi H; Donohue S J; Klein D C; McBride O W
Localization of the hydroxyindole-O-methyltransferase gene to the pseudoautosomal region: implications for mapping of psychiatric disorders.
Human molecular genetics 1993;2(2):127-31.
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1992: Korf H W; White B H; Schaad N C; Klein D C
Recoverin in pineal organs and retinae of various vertebrate species including man.
Brain research 1992;595(1):57-66.
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1992: Babila T; Klein D C
Stimulus deprivation increases pineal Gs alpha and G beta.
Journal of neurochemistry 1992;59(4):1356-62.
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1992: Vanecek J; Klein D C
Sodium-dependent effects of melatonin on membrane potential of neonatal rat pituitary cells.
Endocrinology 1992;131(2):939-46.
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1992: Babila T; Schaad N C; Simonds W F; Shinohara T; Klein D C
Development of MEKA (phosducin), G beta, G gamma and S-antigen in the rat pineal gland and retina.
Brain research 1992;585(1-2):141-8.
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1992: Weller J L; Klein D C
The pineal adrenergic----cyclic GMP response develops two weeks after the adrenergic----cyclic AMP response.
Brain research. Developmental brain research 1992;68(1):144-7.
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1992: Klein D C; Roseboom P H; Donohue S J; Marrs B L
Evolution of melatonin as a night signal: Contribution from a primitive photosynthetic organism.
Molecular and cellular neurosciences 1992;3(3):181-3.
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1992: Klein D C; Schaad N L; Namboordiri M A; Yu L; Weller J L
Regulation of pineal serotonin N-acetyltransferase activity.
Biochemical Society transactions 1992;20(2):299-304.
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1992: Schaad N C; Klein D C
Characterization of alpha 2-adrenergic receptors on rat pinealocytes.
Endocrinology 1992;130(5):2804-10.
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1992: Donohue S J; Roseboom P H; Klein D C
Bovine hydroxyindole-O-methyltransferase. Significant sequence revision.
The Journal of biological chemistry 1992;267(8):5184-5.
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1992: Huang S K; Klein D C; Korf H W
Immunocytochemical demonstration of rod-opsin, S-antigen, and neuron-specific proteins in the human pineal gland.
Cell and tissue research 1992;267(3):493-8.
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1992: Vanecek J; Klein D C
Melatonin inhibits gonadotropin-releasing hormone-induced elevation of intracellular Ca2+ in neonatal rat pituitary cells.
Endocrinology 1992;130(2):701-7.
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1992: Babila T; Schaad N C; Klein D C
Rat pineal Gsa, Gia and Goa: relative abundance and development.
Brain research 1992;572(1-2):232-5.
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1991: Schaad N C; Shinohara T; Abe T; Klein D C
Photoneural control of the synthesis and phosphorylation of pineal MEKA (phosducin).
Endocrinology 1991;129(6):3289-98.
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1991: Ceña V; Halperin J I; Yeandle S; Klein D C
Norepinephrine stimulates potassium efflux from pinealocytes: evidence for involvement of biochemical "AND" gate operated by calcium and adenosine 3',5'-monophosphate.
Endocrinology 1991;128(1):559-69.
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1990: Voisin P; Harrington M G; Weller J L; Goldman D; Merril C R; Klein D C
Noradrenergic control of the synthesis of two rat pineal proteins.
Brain research 1990;517(1-2):25-34.
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1990: Reig J A; Yu L; Klein D C
Pineal transduction. Adrenergic----cyclic AMP-dependent phosphorylation of cytoplasmic 33-kDa protein (MEKA) which binds beta gamma-complex of transducin.
The Journal of biological chemistry 1990;265(10):5816-24.
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1990: Shyjan A W; Ceña V; Klein D C; Levenson R
Differential expression and enzymatic properties of the Na+,K(+)-ATPase alpha 3 isoenzyme in rat pineal glands.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(3):1178-82.
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1989: Nikodijevic O; Klein D C
Adenosine stimulates adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate accumulation in rat pinealocytes: evidence for a role for adenosine in pineal neurotransmission.
Endocrinology 1989;125(4):2150-7.
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1989: Ho A K; Chik C L; Weller J L; Cragoe E J; Klein D C
Evidence of alpha 1-adrenergic----protein kinase C----Na+/H+ antiporter-dependent increase in pinealocyte intracellular pH. Role in the adrenergic stimulation of cGMP accumulation.
The Journal of biological chemistry 1989;264(22):12983-8.
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1989: Ho A K; Chik C L; Klein D C
Forskolin stimulates pinealocyte cGMP accumulation. Dramatic potentiation by an alpha 1-adrenergic----[Ca2+]i mechanism involving protein kinase C.
FEBS letters 1989;249(2):207-12.
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1989: Korf H W; Bruce J A; Vistica B; Rollag M; Stein B M; Klein D C
Immunoreactive S-antigen in cerebrospinal fluid: a marker of pineal parenchymal tumors?
Journal of neurosurgery 1989;70(5):682-7.
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1989: Abe T; Yamaki K; Tsuda M; Singh V K; Suzuki S; McKinnon R; Klein D C; Donoso L A; Shinohara T
Rat pineal S-antigen: sequence analysis reveals presence of alpha-transducin homologous sequence.
FEBS letters 1989;247(2):307-11.
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1989: McCabe R T; Schoenheimer J A; Skolnick P; Newman A H; Rice K C; Reig J A; Klein D C
[3H]AHN 086 acylates peripheral benzodiazepine receptors in the rat pineal gland.
FEBS letters 1989;244(2):263-7.
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1988: Sugden D; Ho A K; Sugden A L; Klein D C
Negative feedback mechanisms: evidence that desensitization of pineal alpha 1-adrenergic responses involves protein kinase-C.
Endocrinology 1988;123(3):1425-32.
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1988: Ho A K; Thomas T P; Chik C L; Anderson W B; Klein D C
Protein kinase C: subcellular redistribution by increased Ca2+ influx. Evidence that Ca2+-dependent subcellular redistribution of protein kinase C is involved in potentiation of beta-adrenergic stimulation of pineal cAMP and cGMP by K+ and A23187.
The Journal of biological chemistry 1988;263(19):9292-7.
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1988: Chik C L; Ho A K; Klein D C
Dual receptor regulation of cyclic nucleotides: alpha 1-adrenergic potentiation of vasoactive intestinal peptide stimulation of pinealocyte adenosine 3',5'-monophosphate.
Endocrinology 1988;122(4):1646-51.
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1988: Ho A K; Chik C L; Klein D C
Effects of protein kinase inhibitor (1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H7) on protein kinase C activity and adrenergic stimulation of cAMP and cGMP in rat pinealocytes.
Biochemical pharmacology 1988;37(6):1015-20.
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1988: Chik C L; Ho A K; Klein D C
Alpha 1-adrenergic potentiation of vasoactive intestinal peptide stimulation of rat pinealocyte adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate: evidence for a role of calcium and protein kinase-C.
Endocrinology 1988;122(2):702-8.
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1988: Sugden D; Klein D C
Activators of protein kinase C act at a postreceptor site to amplify cyclic AMP production in rat pinealocytes.
Journal of neurochemistry 1988;50(1):149-55.
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1988: Ho A K; Chik C L; Klein D C
Permissive role of calcium in alpha 1-adrenergic stimulation of pineal phosphatidylinositol phosphodiesterase (phospholipase C) activity.
Journal of pineal research 1988;5(6):553-64.
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1988: Reig J A; Klein D C
Submicrogram quantities of unstained proteins are visualized on polyvinylidene difluoride membranes by transillumination.
Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society 1988;1(1):59-60.
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1987: González-García C; Ceña V; Klein D C
Characterization of the alpha +-like Na+,K+-ATPase which mediates ouabain inhibition of adrenergic induction of N-acetyltransferase (EC 2.3.1.87) activity: studies with isolated pinealocytes.
Molecular pharmacology 1987;32(6):792-7.
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1987: Ceña V; González-García C; Svoboda P; Weller J L; Klein D C
Developmental study of ouabain inhibition of adrenergic induction of rat pineal serotonin N-acetyltransferase (EC 2.3.1.87).
The Journal of biological chemistry 1987;262(30):14467-71.
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1987: Ho A K; Chik C L; Klein D C
Transmembrane receptor cross-talk: concurrent VIP and alpha 1-adrenergic activation rapidly elevates pinealocyte cGMP greater than 100-fold.
Biochemical and biophysical research communications 1987;146(3):1478-84.
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1987: Ho A K; Chik C L; Klein D C
Protein kinase C is involved in adrenergic stimulation of pineal cGMP accumulation.
The Journal of biological chemistry 1987;262(21):10059-64.
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1987: Namboodiri M A; Brownstein M J; Voisin P; Weller J L; Klein D C
A simple and rapid method for the purification of ovine pineal arylalkylamine N-acetyltransferase.
Journal of neurochemistry 1987;48(2):580-5.
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1987: Namboodiri M A; Brownstein M J; Weller J; Voisin P; Klein D C
Multiple forms of arylalkylamine N-acetyltransferases in the rat pineal gland: purification of one molecular form.
Journal of pineal research 1987;4(3):235-46.
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1987: Namboodiri M A; Dubbels R; Klein D C
Arylalkylamine N-acetyltransferase from mammalian pineal gland.
Methods in enzymology 1987;142():583-90.
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1986: Korf H W; Oksche A; Ekström P; Gery I; Zigler J S; Klein D C
Pinealocyte projections into the mammalian brain revealed with S-antigen antiserum.
Science (New York, N.Y.) 1986;231(4739):735-7.
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1980: Namboodiri M A; Weller J L; Klein D C
Rapid and reversible activation of acetyl CoA hydrolase in intact pineal cells by disulfide exchange.
Biochemical and biophysical research communications 1980;96(1):188-95.
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1980: Namboodiri M A; Weller J L; Klein D C
Evidence of inactivation of pineal indoleamine N-acetyltransferase by protein thiol:disulfide exchange.
The Journal of biological chemistry 1980;255(13):6032-5.
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