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Paul Moore

Research Profile

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Chemicals & Drugs

Anatomy

Cells, Cultured

Living Beings

Physiology

Gene Expression Regulation

Phenomena

Protein Binding

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Publications

TOP 3
Maria-Concetta Veri; Stephen J Burke; Ling Huang; Hua Li; Sergey Gorlatov; Nadine Tuaillon; Godfrey Rainey; Valentina Ciccarone; Tengfei Zhang; Kay Shah; Linda Jin; Lida Ning; Tamara Minor; Paul Moore; Scott Koenig; Syd Johnson; Ezio Bonvini
Therapeutic control of B cell activation via recruitment of Fcgamma receptor IIb (CD32B) inhibitory function with a novel bispecific antibody scaffold.
Syd Johnson; Stephen J Burke; Ling Huang; Sergey Gorlatov; Hua Li; Weili Wang; Wenjun Zhang; Nadine Tuaillon; Godfrey Rainey; Bhaswati Barat; Yinhua Yang; Linda Jin; Valentina Ciccarone; Paul Moore; Scott Koenig; Ezio Bonvini
Effector cell recruitment with novel Fv-based dual-affinity re-targeting protein leads to potent tumor cytolysis and in vivo B-cell depletion.
D D Fang; Y J Kim; C N Lee; S Aggarwal; K McKinnon; D Mesmer; J Norton; C E Birse; Tao He; S M Ruben; Paul Moore
Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery.

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All Publications

2010: Maria-Concetta Veri; Stephen J Burke; Ling Huang; Hua Li; Sergey Gorlatov; Nadine Tuaillon; Godfrey Rainey; Valentina Ciccarone; Tengfei Zhang; Kay Shah; Linda Jin; Lida Ning; Tamara Minor; Paul Moore; Scott Koenig; Syd Johnson; Ezio Bonvini
Therapeutic control of B cell activation via recruitment of Fcgamma receptor IIb (CD32B) inhibitory function with a novel bispecific antibody scaffold.
Arthritis and rheumatism 2010;62(7):1933-43.
2010: Syd Johnson; Stephen J Burke; Ling Huang; Sergey Gorlatov; Hua Li; Weili Wang; Wenjun Zhang; Nadine Tuaillon; Godfrey Rainey; Bhaswati Barat; Yinhua Yang; Linda Jin; Valentina Ciccarone; Paul Moore; Scott Koenig; Ezio Bonvini
Effector cell recruitment with novel Fv-based dual-affinity re-targeting protein leads to potent tumor cytolysis and in vivo B-cell depletion.
Journal of molecular biology 2010;399(3):436-49.
2010: D D Fang; Y J Kim; C N Lee; S Aggarwal; K McKinnon; D Mesmer; J Norton; C E Birse; Tao He; S M Ruben; Paul Moore
Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery.
British journal of cancer 2010;102(8):1265-75.
2009: Sudeepta Aggarwal; Tao He; William Fitzhugh; Kim Rosenthal; Brian Feild; Jenny Heidbrink; Deborah Mesmer; Steven M Ruben; Paul Moore
Immune modulator CD70 as a potential cisplatin resistance predictive marker in ovarian cancer.
Gynecologic oncology 2009;115(3):430-7.
2008: Gordon R Nicol; Mark Han; Jun Kim; Charles E Birse; Erin Brand; Anh Nguyen; Mehdi Mesri; William FitzHugh; Patrick Kaminker; Paul Moore; Steven M Ruben; Tao He
Use of an immunoaffinity-mass spectrometry-based approach for the quantification of protein biomarkers from serum samples of lung cancer patients.
Molecular & cellular proteomics : MCP 2008;7(10):1974-82.
2008: L M Smith; A Nesterova; M C Ryan; S Duniho; M Jonas; M Anderson; R F Zabinski; M. Sutherland; H-P Gerber; K L Van Orden; Paul Moore; S M Ruben; P J Carter
CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers.
British journal of cancer 2008;99(1):100-9.
2008: G. SUBRAMANIAN; Paul Moore; Brian B Gowen; Aaron L Olsen; Dale L Barnard; Jason Paragas; Robert Jeffrey Hogan; Robert W Sidwell
Potent in vitro activity of the albumin fusion type 1 interferons (albumin-interferon-alpha and albumin-interferon-beta) against RNA viral agents of bioterrorism and the severe acute respiratory syndrome (SARS) virus.
Chemotherapy 2008;54(3):176-80.
2007: Bing Han; Paul Moore; Jiangping Wu; Hongyu Luo
Overexpression of human decoy receptor 3 in mice results in a systemic lupus erythematosus-like syndrome.
Arthritis and rheumatism 2007;56(11):3748-58.
2007: Chen Liu; Haizhen Zhu; G. SUBRAMANIAN; Paul Moore; Yiling Xu; David R Nelson
Anti-hepatitis C virus activity of albinterferon alfa-2b in cell culture.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(11):941-7.
2007: Katherine Y Blain; Witek Kwiatkowski; Qinghai Zhao; David La Fleur; Chethana Naik; Tae-Wook Chun; Tatiana Tsareva; Palanisamy Kanakaraj; Michael W Laird; Rutul Shah; Lisa George; Indra Sanyal; Paul Moore; Borries Demeler; Senyon Choe
Structural and functional characterization of CC chemokine CCL14.
Biochemistry 2007;46(35):10008-15.
2006: Vijayan Balan; L Aravind; Diane E Grill; Terry M Therneau; Mark S Sulkowski; David R Nelson; Jens Praestgaard; Marianne Rosati; Charles E Birse; Paul Moore; G Mani Subramanian
Global transcriptional effects of PEG-IFN-alpha and ribavirin on peripheral blood cells obtained from patients with chronic hepatitis C.
Hepatology research : the official journal of the Japan Society of Hepatology 2006;36(4):277-87.
2006: Satish Devadas; Jyoti Das; Catherine Liu; Liying Zhang; Arthur I Roberts; Zui Pan; Paul Moore; Gobardhan Das; Yufang Shi
Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells.
Immunity 2006;25(2):237-47.
2006: Vincent G Bain; Eric M Yoshida; Kelly D Kaita; Mark G Swain; E Jenny Heathcote; Andy Garcia; Paul Moore; Ren Yu; John G McHutchison; G. SUBRAMANIAN
Dynamics of interferon-specific gene expression in peripheral blood of interferon alfa-naïve patients with genotype 1 chronic hepatitis C infection treated with albumin-interferon alfa.
Hepatology research : the official journal of the Japan Society of Hepatology 2006;35(4):256-62.
2006: Claudia Scarponi; Bernardetta Nardelli; David W LaFleur; Paul Moore; Stefania Madonna; Ornella De Pità; Giampiero Girolomoni; Cristina Albanesi
Analysis of IFN-kappa expression in pathologic skin conditions: downregulation in psoriasis and atopic dermatitis.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2006;26(3):133-40.
2006: Vijayan Balan; David R Nelson; Mark S Sulkowski; Gregory T Everson; Louis R Lambiase; Rusell H Wiesner; Rolland C Dickson; Andy Garcia; Paul Moore; Ren Yu; G. SUBRAMANIAN
Modulation of interferon-specific gene expression by albumin-interferon-alpha in interferon-alpha-experienced patients with chronic hepatitis C.
Antiviral therapy 2006;11(7):901-8.
2006: Bernardetta Nardelli; Liubov Zaritskaya; William McAuliffe; Yansong Ni; Clint Lincoln; Yun Hee Cho; Charles E Birse; Wendy Halpern; Stephen Ullrich; Paul Moore
Osteostat/tumor necrosis factor superfamily 18 inhibits osteoclastogenesis and is selectively expressed by vascular endothelial cells.
Endocrinology 2006;147(1):70-8.
2004: Sunghee Kim; William McAuliffe; Liubov Zaritskaya; Paul Moore; Lurong Zhang; Bernardetta Nardelli
Selective induction of tumor necrosis receptor factor 6/decoy receptor 3 release by bacterial antigens in human monocytes and myeloid dendritic cells.
Infection and immunity 2004;72(1):89-93.
2003: Yulian Wu; Bing Han; Hongyu Luo; Raphael Roduit; Theodora W Salcedo; Paul Moore; Jun Zhang; Jiangping Wu
DcR3/TR6 effectively prevents islet primary nonfunction after transplantation.
Diabetes 2003;52(9):2279-86.
2003: Yulian Wu; Bing Han; Hongwei Sheng; Min Lin; Paul Moore; Jun Zhang; Jiangping Wu
Clinical significance of detecting elevated serum DcR3/TR6/M68 in malignant tumor patients.
International journal of cancer. Journal international du cancer 2003;105(5):724-32.
2003: Cynthia Sung; Bernardetta Nardelli; David W LaFleur; Erich Blatter; Marta Corcoran; Henrik S Olsen; Charles E Birse; Oxana Pickeral; Junli Zhang; Devanshi Shah; Gordon Moody; Solange Gentz; Lisa Beebe; Paul Moore
An IFN-beta-albumin fusion protein that displays improved pharmacokinetic and pharmacodynamic properties in nonhuman primates.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2003;23(1):25-36.
2002: Bernardetta Nardelli; Liubov Zaritskaya; Mark Semenuk; Yun Hee Cho; David W LaFleur; Devanshi Shah; Stephen Ullrich; Giampiero Girolomoni; Cristina Albanesi; Paul Moore
Regulatory effect of IFN-kappa, a novel type I IFN, on cytokine production by cells of the innate immune system.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):4822-30.
2002: Bernardetta Nardelli; Paul Moore; Yuling Li; David M Hilbert
B lymphocyte stimulator (BLyS): a therapeutic trichotomy for the treatment of B lymphocyte diseases.
Leukemia & lymphoma 2002;43(7):1367-73.
2002: Runqing Lu; Paul Moore; PAULA PITHA-ROWE
Stimulation of IRF-7 gene expression by tumor necrosis factor alpha: requirement for NFkappa B transcription factor and gene accessibility.
The Journal of biological chemistry 2002;277(19):16592-8.
2002: Thi-Sau Migone; Jun Zhang; Xia Luo; Li Zhuang; Cecil Chen; Bugen Hu; June S Hong; James W Perry; Su Fang Chen; Joe X H Zhou; Yun Hee Cho; Stephen Ullrich; Palanisamy Kanakaraj; Jeffrey Carrell; Ernest Boyd; Henrik S Olsen; Gang Hu; Laurie Pukac; Ding Liu; Jian Ni; Sunghee Kim; Reiner Gentz; Ping Feng; Paul Moore; Steve Ruben; Ping Wei
TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator.
Immunity 2002;16(3):479-92.
2001: David W LaFleur; Bernardetta Nardelli; T Tsareva; D Mather; Ping Feng; Mark Semenuk; K Taylor; M Buergin; D Chinchilla; V Roshke; G Chen; Steve Ruben; PAULA PITHA-ROWE; Timothy A Coleman; Paul Moore
Interferon-kappa, a novel type I interferon expressed in human keratinocytes.
The Journal of biological chemistry 2001;276(43):39765-71.
2001: K Connolly; Yun Hee Cho; R Duan; J Fikes; T Gregorio; David W LaFleur; Z Okoye; TW Salcedo; G Santiago; Stephen Ullrich; Ping Wei; K Windle; E Wong; Xiao-Tao Yao; Y Q Zhang; G Zheng; Paul Moore
In vivo inhibition of Fas ligand-mediated killing by TR6, a Fas ligand decoy receptor.
The Journal of pharmacology and experimental therapeutics 2001;298(1):25-33.
2001: Betsy J Barnes; Paul Moore; PAULA PITHA-ROWE
Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes.
The Journal of biological chemistry 2001;276(26):23382-90.
2001: Jun Zhang; TW Salcedo; X Wan; Stephen Ullrich; Bugen Hu; T Gregorio; Ping Feng; S Qi; H Chen; Yun Hee Cho; Yuling Li; Paul Moore; J Wu
Modulation of T-cell responses to alloantigens by TR6/DcR3.
The Journal of clinical investigation 2001;107(11):1459-68.
2001: Richard T Richardson; Perumal Sivashanmugam; Susan H Hall; Katherine G Hamil; Paul Moore; Steve Ruben; Frank S French; Michael G O'Rand
Cloning and sequencing of human Eppin: a novel family of protease inhibitors expressed in the epididymis and testis.
Gene 2001;270(1-2):93-102.
2001: Bernardetta Nardelli; Ornella Belvedere; Viktor Roschke; Paul Moore; Henrik S Olsen; Thi-Sau Migone; Svetlana Sosnovtseva; Jeffrey Carrell; Ping Feng; Judith Goldstein Giri; David M Hilbert
Synthesis and release of B-lymphocyte stimulator from myeloid cells.
Blood 2001;97(1):198-204.
2000: Y Wu; D Bressette; Jeffrey Carrell; T Kaufman; Ping Feng; K Taylor; Y Gan; Yun Hee Cho; A D Garcia; E Gollatz; D Dimke; David W LaFleur; Thi-Sau Migone; Bernardetta Nardelli; Ping Wei; Steve Ruben; Stephen Ullrich; Henrik S Olsen; Palanisamy Kanakaraj; Paul Moore; Kevin P Baker
Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS.
The Journal of biological chemistry 2000;275(45):35478-85.
2000: Mirella Giovarelli; Paola Cappello; Guido Forni; TW Salcedo; Paul Moore; D W LeFleur; Bernardetta Nardelli; E Di Carlo; Pier-Luigi Lollini; Steve Ruben; Stephen Ullrich; G Garotta; Piero Musiani
Tumor rejection and immune memory elicited by locally released LEC chemokine are associated with an impressive recruitment of APCs, lymphocytes, and granulocytes.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(6):3200-6.
2000: J Ozer; Paul Moore; Paul M Lieberman
A testis-specific transcription factor IIA (TFIIAtau) stimulates TATA-binding protein-DNA binding and transcription activation.
The Journal of biological chemistry 2000;275(1):122-8.
1999: Paul Moore; J Ozer; M Salunek; G Jan; D Zerby; S Campbell; Paul M Lieberman
A human TATA binding protein-related protein with altered DNA binding specificity inhibits transcription from multiple promoters and activators.
Molecular and cellular biology 1999;19(11):7610-20.
1999: WJ Lowther; Paul Moore; K C Carter; PAULA PITHA-ROWE
Cloning and functional analysis of the human IRF-3 promoter.
DNA and cell biology 1999;18(9):685-92.
1999: YP Xia; Y Zhao; J Marcus; P A Jimenez; S M Ruben; Paul Moore; F Khan; Thomas A Mustoe
Effects of keratinocyte growth factor-2 (KGF-2) on wound healing in an ischaemia-impaired rabbit ear model and on scar formation.
The Journal of pathology 1999;188(4):431-8.
1999: Paul Moore; Ornella Belvedere; A Orr; K Pieri; David W LaFleur; Ping Feng; D Soppet; M Charters; Reiner Gentz; D Parmelee; Yuling Li; Olga Galperina; Judith Goldstein Giri; Viktor Roschke; Bernardetta Nardelli; Jeffrey Carrell; Svetlana Sosnovtseva; W Greenfield; Steve Ruben; Henrik S Olsen; J Fikes; David M Hilbert
BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator.
Science (New York, N.Y.) 1999;285(5425):260-3.
1999: Bryant G Darnay; Jian Ni; Paul Moore; Bharat B Aggarwal
Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif.
The Journal of biological chemistry 1999;274(12):7724-31.
1998: Wei-Chun Au; Paul Moore; David W LaFleur; Bertrand Tombal; PAULA PITHA-ROWE
Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes.
The Journal of biological chemistry 1998;273(44):29210-7.
1998: Bryant G Darnay; Valsala Haridas; Jian Ni; Paul Moore; Bharat B Aggarwal
Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N-terminal kinase.
The Journal of biological chemistry 1998;273(32):20551-5.
1998: PAULA PITHA-ROWE; Wei-Chun Au; WJ Lowther; YT Juang; SL Schafer; L Burysek; J Hiscott; Paul Moore
Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth.
Biochimie 1998;80(8-9):651-8.
1998: Elizabeth R Smith; J M Belote; R L Schiltz; X J Yang; Paul Moore; S L Berger; Y Nakatani; C David Allis
Cloning of Drosophila GCN5: conserved features among metazoan GCN5 family members.
Nucleic acids research 1998;26(12):2948-54.
1998: SL Schafer; R Lin; Paul Moore; J Hiscott; PAULA PITHA-ROWE
Regulation of type I interferon gene expression by interferon regulatory factor-3.
The Journal of biological chemistry 1998;273(5):2714-20.
1997: KC Carter; L Wang; BK Shell; I Zamir; S L Berger; Paul Moore
The human transcriptional adaptor genes TADA2L and GCN5L2 colocalize to chromosome 17q12-q21 and display a similar tissue expression pattern.
Genomics 1997;40(3):497-500.
1996: Paul Moore; C A Rosen; K C Carter
Assignment of the human FKBP12-rapamycin-associated protein (FRAP) gene to chromosome 1p36 by fluorescence in situ hybridization.
Genomics 1996;33(2):331-2.
1996: R Candau; Paul Moore; L Wang; Nickolai A Barlev; C Y Ying; C A Rosen; Shelley L Berger
Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5.
Molecular and cellular biology 1996;16(2):593-602.
1996: F A Sagliocco; Paul Moore; A J Brown
Polysome analysis.
Methods in molecular biology (Clifton, N.J.) 1996;53():297-311.
1995: Wei-Chun Au; Paul Moore; WJ Lowther; YT Juang; PAULA PITHA-ROWE
Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11657-61.
1995: K McKune; Paul Moore; M W Hull; Nancy A Woychik
Six human RNA polymerase subunits functionally substitute for their yeast counterparts.
Molecular and cellular biology 1995;15(12):6895-900.
1994: J Ozer; Paul Moore; A H Bolden; A Lee; C A Rosen; Paul M Lieberman
Molecular cloning of the small (gamma) subunit of human TFIIA reveals functions critical for activated transcription.
Genes & development 1994;8(19):2324-35.
1993: Paul Moore; S M Ruben; C A Rosen
Conservation of transcriptional activation functions of the NF-kappa B p50 and p65 subunits in mammalian cells and Saccharomyces cerevisiae.
Molecular and cellular biology 1993;13(3):1666-74.
1993: B Ohana; Paul Moore; Steve Ruben; C D Southgate; M R Green; C A Rosen
The type 1 human immunodeficiency virus Tat binding protein is a transcriptional activator belonging to an additional family of evolutionarily conserved genes.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):138-42.
1991: Paul Moore; F A Sagliocco; R M Wood; Alistair J P Brown
Yeast glycolytic mRNAs are differentially regulated.
Molecular and cellular biology 1991;11(10):5330-7.
1990: Paul Moore; A J Bettany; Alistair J P Brown
Multiple copies of the pyruvate kinase gene affect yeast cell growth.
Journal of general microbiology 1990;136(12):2359-66.
1990: S D Finlayson; Paul Moore; J R Johnston; David R Berry
Two staining methods for selectively detecting isomaltase and maltase activity in electrophoresis gels.
Analytical biochemistry 1990;186(2):233-5.
1990: Paul Moore; A J Bettany; J P Brown
Expression of a yeast glycolytic gene is subject to dosage limitation.
Gene 1990;89(1):85-92.
1989: A J Bettany; Paul Moore; R Cafferkey; L D Bell; A R Goodey; B L Carter; Alistair J P Brown
5'-secondary structure formation, in contrast to a short string of non-preferred codons, inhibits the translation of the pyruvate kinase mRNA in yeast.
Yeast (Chichester, England) 1989;5(3):187-98.