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Elke Butt

Research Profile

Chemicals & Drugs

Anatomy

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Phosphorylation

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Amino Acid Sequences

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Publications

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S Mihlan; H J Pavenstädt; C Reiß; Albert Sickmann; P Thalheimer; S Gaetzner; Sabine Herterich; Joachim Kremerskothen; Urs Lewandrowski; Elke Butt
Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions.
Stepan Gambaryan; Joerg Geiger; Anna Kobsar; Viacheslav O Nikolaev; Rimma Parnova; Natalia Rukoyatkina; Elke Butt; Ulrich Walter
The oligopeptide DT-2 is a specific PKG I inhibitor only in vitro, not in living cells.
Thomas G P Grunewald; Kristina Hauer; Urs Lewandrowski; Katharina Lohrig; Carsten Müller-Tidow; Frauke Neff; Stephanie Plehm; Günther H S Richter; Albert Sickmann; Uwe Thiel; Rebekka Unland; Colette Zobywalski; Olivia Prazeres da Costa; Elke Butt; Andrea Cossarizza; Patricia da Silva-Buttkus; Isabel Diebold; Irene Esposito; Agnes Görlach; Stefan Burdach
STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors.

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All Publications

2013: S Mihlan; H J Pavenstädt; C Reiß; Albert Sickmann; P Thalheimer; S Gaetzner; Sabine Herterich; Joachim Kremerskothen; Urs Lewandrowski; Elke Butt
Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions.
Oncogene 2013;32(16):2107-13.
2012: Stepan Gambaryan; Joerg Geiger; Anna Kobsar; Viacheslav O Nikolaev; Rimma Parnova; Natalia Rukoyatkina; Elke Butt; Ulrich Walter
The oligopeptide DT-2 is a specific PKG I inhibitor only in vitro, not in living cells.
British journal of pharmacology 2012;167(4):826-38.
2012: Thomas G P Grunewald; Kristina Hauer; Urs Lewandrowski; Katharina Lohrig; Carsten Müller-Tidow; Frauke Neff; Stephanie Plehm; Günther H S Richter; Albert Sickmann; Uwe Thiel; Rebekka Unland; Colette Zobywalski; Olivia Prazeres da Costa; Elke Butt; Andrea Cossarizza; Patricia da Silva-Buttkus; Isabel Diebold; Irene Esposito; Agnes Görlach; Stefan Burdach
STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors.
Molecular cancer research : MCR 2012;10(1):52-65.
2011: Semjon Willier; Günther H S Richter; Stefan Burdach; Elke Butt; Thomas G P Grunewald
Defining the role of TRIP6 in cell physiology and cancer.
Biology of the cell / under the auspices of the European Cell Biology Organization 2011;103(12):573-91.
2011: Katharina Werner; Jörg Geiger; Hans-Gottfried Genieser; Frank Schwede; Elke Butt
Quantification of cAMP and cGMP analogs in intact cells: pitfalls in enzyme immunoassays for cyclic nucleotides.
Naunyn-Schmiedeberg's archives of pharmacology 2011;384(2):169-76.
2011: Gaby Wangorsch; Elke Butt; Thomas Dandekar; Joerg Geiger; Katharina Hubertus; Regina Mark; Marcus Dittrich
Time-resolved in silico modeling of fine-tuned cAMP signaling in platelets: feedback loops, titrated phosphorylations and pharmacological modulation.
BMC systems biology 2011;5():178.
2010: Christopher Traenka; Marc Remke; Andrey Korshunov; Sebastian Bender; Thomas Hielscher; Paul A Northcott; Hendrik Witt; Marina Ryzhova; Jörg Felsberg; Axel Benner; Stephanie Riester; Wolfram Scheurlen; Thomas G P Grunewald; Andreas von Deimling; Andreas E Kulozik; Guido Reifenberger; Michael D Taylor; Peter Lichter; Elke Butt; Stefan M Pfister
Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma.
Cancer research 2010;70(20):8003-14.
2010: J J Frietsch; T G P Grunewald; S Jasper; Ulrike Kammerer; Sabine Herterich; Michaela Kapp; Arnd Honig; Elke Butt
Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer.
British journal of cancer 2010;102(11):1645-53.
2009: Julia Traenka; Christof R Hauck; Urs Lewandrowski; Albert Sickmann; Stepan Gambaryan; Petra Thalheimer; Elke Butt
Integrin-dependent translocation of LASP-1 to the cytoskeleton of activated platelets correlates with LASP-1 phosphorylation at tyrosine 171 by Src-kinase.
Thrombosis and haemostasis 2009;102(3):520-8.
2007: Martin Vielreicher; Gregory S Harms; Elke Butt; Ulrich Walter; Achim Obergfell
Dynamic interaction between Src and C-terminal Src kinase in integrin alphaIIbbeta3-mediated signaling to the cytoskeleton.
The Journal of biological chemistry 2007;282(46):33623-31.
2007: Thomas Grunewald; Ulrike Kammerer; C Winkler; Detlev Schindler; Albert Sickmann; Arnd Honig; Elke Butt
Overexpression of LASP-1 mediates migration and proliferation of human ovarian cancer cells and influences zyxin localisation.
British journal of cancer 2007;96(2):296-305.
2007: Thomas Grunewald; Ulrike Kammerer; Michaela Kapp; Matthias Eck; Johannes Dietl; Elke Butt; Arnd Honig
Nuclear localization and cytosolic overexpression of LASP-1 correlates with tumor size and nodal-positivity of human breast carcinoma.
BMC cancer 2007;7():198.
2006: Thomas Grunewald; Ulrike Kammerer; Elfriede Schulze; Detlev Schindler; Arnd Honig; Michael Zimmer; Elke Butt
Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells.
Experimental cell research 2006;312(7):974-82.
2006: Stepan Gambaryan; Elke Butt; Piet Tas; Albert Smolenski; Bruno Allolio; Ulrich Walter
Regulation of aldosterone production from zona glomerulosa cells by ANG II and cAMP: evidence for PKA-independent activation of CaMK by cAMP.
American journal of physiology. Endocrinology and metabolism 2006;290(3):E423-33.
2004: Christian Keicher; Stepan Gambaryan; Elfriede Schulze; Katrin Marcus; Helmut E Meyer; Elke Butt
Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.
Biochemical and biophysical research communications 2004;324(1):308-16.
2004: Stepan Gambaryan; Joerg Geiger; Ulrike R Schwarz; Elke Butt; Antonija Begonja; Achim Obergfell; Ulrich Walter
Potent inhibition of human platelets by cGMP analogs independent of cGMP-dependent protein kinase.
Blood 2004;103(7):2593-600.
2003: Yoshiaki Hirako; Yuji Nishizawa; Cassian Sitaru; Andreas Opitz; Katrin Marcus; Helmut E Meyer; Elke Butt; Katsushi Owaribe; Detlef Zillikens
The 97-kDa (LABD97) and 120-kDa (LAD-1) fragments of bullous pemphigoid antigen 180/type XVII collagen have different N-termini.
The Journal of investigative dermatology 2003;121(6):1554-6.
2003: Iakov Shimanovich; Yoshiaki Hirako; Cassian Sitaru; Takashi Hashimoto; Eva-B Bröcker; Elke Butt; Detlef Zillikens
The autoantigen of anti-p200 pemphigoid is an acidic noncollagenous N-linked glycoprotein of the cutaneous basement membrane.
The Journal of investigative dermatology 2003;121(6):1402-8.
2003: Yu Shi; Alexey Kotlyarov; Kathrin Laabeta; Achim D Gruber; Elke Butt; Katrin Marcus; Helmut E Meyer; Anke Friedrich; Hans-Dieter Volk; Matthias Gaestel
Elimination of protein kinase MK5/PRAK activity by targeted homologous recombination.
Molecular and cellular biology 2003;23(21):7732-41.
2003: Stepan Gambaryan; Elke Butt; Katrin Marcus; Margarita Glazova; Alois Palmetshofer; gilles guillon; Albert Smolenski
cGMP-dependent protein kinase type II regulates basal level of aldosterone production by zona glomerulosa cells without increasing expression of the steroidogenic acute regulatory protein gene.
The Journal of biological chemistry 2003;278(32):29640-8.
2003: Elke Butt; Stepan Gambaryan; Nina Göttfert; Annette B Galler; Katrin Marcus; Helmut E Meyer
Actin binding of human LIM and SH3 protein is regulated by cGMP- and cAMP-dependent protein kinase phosphorylation on serine 146.
The Journal of biological chemistry 2003;278(18):15601-7.
2002: Kai C Wollert; Beate Fiedler; Stepan Gambaryan; Albert Smolenski; Jörg Heineke; Elke Butt; Christian Trautwein; Suzanne M Lohmann; Helmut Drexler
Gene transfer of cGMP-dependent protein kinase I enhances the antihypertrophic effects of nitric oxide in cardiomyocytes.
Hypertension 2002;39(1):87-92.
2001: B Bader; Elke Butt; Alois Palmetshofer; Ulrich Walter; T Jarchau; P Drueckes
A cGMP-dependent protein kinase assay for high throughput screening based on time-resolved fluorescence resonance energy transfer.
Journal of biomolecular screening 2001;6(4):255-64.
2001: Elke Butt; D Immler ; Helmut E Meyer; Alexey Kotlyarov; Kathrin Laass; Matthias Gaestel
Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants.
The Journal of biological chemistry 2001;276(10):7108-13.
2001: TA Fischer; Alois Palmetshofer; Stepan Gambaryan; Elke Butt; Christian Jassoy; Ulrich Walter; Sieghart Sopper; Suzanne M Lohmann
Activation of cGMP-dependent protein kinase Ibeta inhibits interleukin 2 release and proliferation of T cell receptor-stimulated human peripheral T cells.
The Journal of biological chemistry 2001;276(8):5967-74.
2000: M Burkhardt; Margarita Glazova; Stepan Gambaryan; T Vollkommer; Elke Butt; B Bader; K Heermeier; T M Lincoln; Ulrich Walter; Alois Palmetshofer
KT5823 inhibits cGMP-dependent protein kinase activity in vitro but not in intact human platelets and rat mesangial cells.
The Journal of biological chemistry 2000;275(43):33536-41.
2000: Elke Butt; M Bernhardt; Albert Smolenski; Peter Kotsonis; Lothar G Fröhlich; Albert Sickmann; Helmut E Meyer; Suzanne M Lohmann; Harald Schmidt
Endothelial nitric-oxide synthase (type III) is activated and becomes calcium independent upon phosphorylation by cyclic nucleotide-dependent protein kinases.
The Journal of biological chemistry 2000;275(7):5179-87.
1998: Albert Smolenski; A M Burkhardt; Martin Eigenthaler; Elke Butt; Stepan Gambaryan; Suzanne M Lohmann; Ulrich Walter
Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects.
Naunyn-Schmiedeberg's archives of pharmacology 1998;358(1):134-9.