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Nywana Sizemore

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Muzaffer Cicek; Ryuichi Fukuyama; Mine S Cicek; Steven Sizemore; Danny R Welch; Nywana Sizemore; Graham Casey
BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-kappaB binding site of the uPA promoter.
Ryuichi Fukuyama; R Niculaita; K P Ng; E Obusez; J Sanchez; Matthew F Kalady; P P Aung; Graham Casey; Nywana Sizemore
Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription.
David B Shultz; John D Fuller; Yonghui Yang; Nywana Sizemore; M R Sandhya Rani; George R Stark
Activation of a subset of genes by IFN-gamma requires IKKbeta but not interferon-dependent activation of NF-kappaB.

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All Publications

2009: Muzaffer Cicek; Ryuichi Fukuyama; Mine S Cicek; Steven Sizemore; Danny R Welch; Nywana Sizemore; Graham Casey
BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-kappaB binding site of the uPA promoter.
Clinical & experimental metastasis 2009;26(3):229-37.
2008: Ryuichi Fukuyama; R Niculaita; K P Ng; E Obusez; J Sanchez; Matthew F Kalady; P P Aung; Graham Casey; Nywana Sizemore
Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription.
Oncogene 2008;27(46):6044-55.
2007: David B Shultz; John D Fuller; Yonghui Yang; Nywana Sizemore; M R Sandhya Rani; George R Stark
Activation of a subset of genes by IFN-gamma requires IKKbeta but not interferon-dependent activation of NF-kappaB.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2007;27(10):875-84.
2007: Steven Sizemore; Muzaffer Cicek; Nywana Sizemore; Kwok Peng Ng; Graham Casey
Podocalyxin increases the aggressive phenotype of breast and prostate cancer cells in vitro through its interaction with ezrin.
Cancer research 2007;67(13):6183-91.
2007: Ryuichi Fukuyama; Kwok Peng Ng; Muzaffer Cicek; Clare Kelleher; Roxana Niculaita; Graham Casey; Nywana Sizemore
Role of IKK and oscillatory NFkappaB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells.
Molecular carcinogenesis 2007;46(5):402-13.
2007: Jianhong Yao; Tae Whan Kim; Jianzhong Qin; Zhengfan Jiang; Youcun Qian; Hui Xiao; Yi Lu; Wen Qian; Muhammet Fatih Gulen; Nywana Sizemore; Joseph A DiDonato; Shintaro Sato; Shizuo Akira; Bing Su; Xiaoxia Li
Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification.
The Journal of biological chemistry 2007;282(9):6075-89.
2005: Minoru Horinaga; Ryuichi Fukuyama; Toru Nishiyama; Kelley M Harsch; Muzaffer Cicek; Warren D W Heston; Nywana Sizemore; Graham Casey; William Larchian
Novel enhanced lung-colonizing variant of murine MBT-2 bladder cancer cells.
Urology 2005;66(3):676-81.
2005: Muzaffer Cicek; Ryuichi Fukuyama; Danny R Welch; Nywana Sizemore; Graham Casey
Breast cancer metastasis suppressor 1 inhibits gene expression by targeting nuclear factor-kappaB activity.
Cancer research 2005;65(9):3586-95.
2005: Anju Agarwal; Kingshuk Das; Natalia Lerner; Swati S Sathe; Muzaffer Cicek; Graham Casey; Nywana Sizemore
The AKT/I kappa B kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-kappa B and beta-catenin.
Oncogene 2005;24(6):1021-31.
2004: Nywana Sizemore; Anju Agarwal; Kingshuk Das; Natalia Lerner; Michael Sulak; Sandhya Rani; Richard M Ransohoff; David Shultz; George R Stark
Inhibitor of kappaB kinase is required to activate a subset of interferon gamma-stimulated genes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(21):7994-8.
2004: Swati S Sathe; Nywana Sizemore; Xiaoxia Li; Kalpa Vithalani; Mairead Commane; Shannon M Swiatkowski; George R Stark
Mutant human cells with constitutive activation of NF-kappaB.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):192-7.
2003: Joo Y Lee; Jianping Ye; Zhanguo Gao; Hyung S Youn; Won H Lee; Ling Zhao; Nywana Sizemore; Daniel H Hwang
Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids.
The Journal of biological chemistry 2003;278(39):37041-51.
2002: M R Sandhya Rani; Linda Hibbert; Nywana Sizemore; George R Stark; Richard M Ransohoff
Requirement of phosphoinositide 3-kinase and Akt for interferon-beta-mediated induction of the beta-R1 (SCYB11) gene.
The Journal of biological chemistry 2002;277(41):38456-61.
2002: Nywana Sizemore; Natalia Lerner; Nicole Dombrowski; Hiroaki Sakurai; George R Stark
Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.
The Journal of biological chemistry 2002;277(6):3863-9.
2001: M R Sandhya Rani; A R Asthagiri; A Singh; Nywana Sizemore; Swati S Sathe; Xiaoxia Li; J D DiDonato; George R Stark; Richard M Ransohoff
A role for NF-kappa B in the induction of beta-R1 by interferon-beta.
The Journal of biological chemistry 2001;276(48):44365-8.
2000: Nada Bulus; H M Sheng; Nywana Sizemore; SM Oldham; Joey V Barnett; Robert J Coffey; DR Beauchamp; John A Barnard
Ras-mediated suppression of TGFbetaRII expression in intestinal epithelial cells involves Raf-independent signaling.
Neoplasia (New York, N.Y.) 2000;2(4):357-64.
1999: Nywana Sizemore; Adrienne D Cox; John A Barnard; SM Oldham; ER Reynolds; Channing J Der; Robert J Coffey
Pharmacological inhibition of Ras-transformed epithelial cell growth is linked to down-regulation of epidermal growth factor-related peptides.
Gastroenterology 1999;117(3):567-76.
1999: Nywana Sizemore; Stewart Leung; George R Stark
Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit.
Molecular and cellular biology 1999;19(7):4798-805.
1998: Nywana Sizemore; Chee-Keong Choo; Richard L Eckert; Ellen A Rorke
Transcriptional regulation of the EGF receptor promoter by HPV16 and retinoic acid in human ectocervical epithelial cells.
Experimental cell research 1998;244(1):349-56.
1998: Ellen A Rorke; Nywana Sizemore; Hasan Mukhtar; Letha H Couch; Paul C Howard
Polycyclic aromatic hydrocarbons enhance terminal cell death of human ectocervical cells.
International journal of oncology 1998;13(3):557-63.
1998: SM Oldham; Adrienne D Cox; ER Reynolds; Nywana Sizemore; Robert J Coffey; Channing J Der
Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade.
Oncogene 1998;16(20):2565-73.
1997: Lisa Gangarosa; Nywana Sizemore; Ramona Graves-Deal; SM Oldham; Channing J Der; Robert J Coffey
A raf-independent epidermal growth factor receptor autocrine loop is necessary for Ras transformation of rat intestinal epithelial cells.
The Journal of biological chemistry 1997;272(30):18926-31.
1996: Nywana Sizemore; R C Dudeck; C M Barksdale; G D Nordblom; W Thomas Mueller; Patrick McConnell; DS Wright; A Guglietta; B S Kuo
Development and validation of two solid-phase enzyme immunoassays (ELISA) for quantitation of human epidermal growth factors (hEGFs).
Pharmaceutical research 1996;13(7):1088-94.
1996: Nywana Sizemore; DS Wright; W Thomas Mueller; B S Kuo
Impact of receptor downregulation on clearance of two human EGFs with different receptor binding activity.
Peptides 1996;17(7):1229-36.
1995: D Macinga; V Jain; Nywana Sizemore; George I Gorodeski; Richard L Eckert; Ellen A Rorke
Tamoxifen regulation of ectocervical cell differentiation.
Journal of the Society for Gynecologic Investigation 1995;2(6):754-61.
1995: Nywana Sizemore; Hasan Mukhtar; Letha H Couch; Paul C Howard; Ellen A Rorke
Differential response of normal and HPV immortalized ectocervical epithelial cells to B[a]P.
Carcinogenesis 1995;16(10):2413-8.
1995: James Jacobberger; Nywana Sizemore; George I Gorodeski; Ellen A Rorke
Transforming growth factor beta regulation of epidermal growth factor receptor in ectocervical epithelial cells.
Experimental cell research 1995;220(2):390-6.
1995: Richard L Eckert; C Agarwal; J R Hembree; C K Choo; Nywana Sizemore; sheila Andreatta-van Leyen; Ellen A Rorke
Human cervical cancer. Retinoids, interferon and human papillomavirus.
Advances in experimental medicine and biology 1995;375():31-44.
1993: Nywana Sizemore; Ellen A Rorke
Human papillomavirus 16 immortalization of normal human ectocervical epithelial cells alters retinoic acid regulation of cell growth and epidermal growth factor receptor expression.
Cancer research 1993;53(19):4511-7.
1993: Nywana Sizemore; Lakshmi Kasturi; George I Gorodeski; Richard L Eckert; A M Jetten; Ellen A Rorke
Retinoid regulation of human ectocervical epithelial cell transglutaminase activity and keratin gene expression.
Differentiation; research in biological diversity 1993;54(3):219-25.
1993: Lakshmi Kasturi; Nywana Sizemore; Richard L Eckert; K Martin; Ellen A Rorke
Calcium modulates cornified envelope formation, involucrin content, and transglutaminase activity in cultured human ectocervical epithelial cells.
Experimental cell research 1993;205(1):84-90.