FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

David Weaver

Research Profile

Chemicals & Drugs

Physiology

Anatomy

Phenomena

Phosphorylation

Co-author Network

Publications

TOP 3
Lei Jin; Pramod Pandey; Robert E Babine; David Weaver; Sherin S Abdel-Meguid; James E Strickler
Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors.
Lei Jin; Pramod Pandey; Robert E Babine; Joan C Gorga; Katherine J Seidl; Ellen Gelfand; David Weaver; Sherin S Abdel-Meguid; James E Strickler
Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions.
Lei Jin; Scott Pluskey; Eugene C Petrella; Susan M Cantin; Joan C Gorga; Michael J Rynkiewicz; Pramod Pandey; James E Strickler; Robert E Babine; David Weaver; Katherine J Seidl
The three-dimensional structure of the ZAP-70 kinase domain in complex with staurosporine: implications for the design of selective inhibitors.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of David Weaver (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2005: Lei Jin; Pramod Pandey; Robert E Babine; David Weaver; Sherin S Abdel-Meguid; James E Strickler
Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 10):1418-25.
2005: Lei Jin; Pramod Pandey; Robert E Babine; Joan C Gorga; Katherine J Seidl; Ellen Gelfand; David Weaver; Sherin S Abdel-Meguid; James E Strickler
Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions.
The Journal of biological chemistry 2005;280(6):4704-12.
2004: Lei Jin; Scott Pluskey; Eugene C Petrella; Susan M Cantin; Joan C Gorga; Michael J Rynkiewicz; Pramod Pandey; James E Strickler; Robert E Babine; David Weaver; Katherine J Seidl
The three-dimensional structure of the ZAP-70 kinase domain in complex with staurosporine: implications for the design of selective inhibitors.
The Journal of biological chemistry 2004;279(41):42818-25.
2004: Junran Zhang; Henning Willers; Zhihui Feng; Jagadish C Ghosh; Sang Kim; David Weaver; Jay H Chung; Simon Nicholas Powell; Fang Xia
Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.
Molecular and cellular biology 2004;24(2):708-18.
2002: Koji Nakanishi; Toshiyasu Taniguchi; Velvizhi Ranganathan; Helen V New; Lisa A Moreau; Maria Stotsky; Christopher G Mathew; Michael B Kastan; David Weaver; Alan D D'Andrea
Interaction of FANCD2 and NBS1 in the DNA damage response.
Nature cell biology 2002;4(12):913-20.
2001: Velvizhi Ranganathan; WF Heine; David N Ciccone; K L Rudolph; X Wu; S Chang; H Hai; I M Ahearn; David M Livingston; I Resnick; F Rosen; E Seemanova; Petr Jarolim; Ronald A DePinho; David Weaver
Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit.
Current biology : CB 2001;11(12):962-6.
2001: I Han; S Harada; David Weaver; Y Xue; William Stratton Lane; Sigurd Orstavik; B Skalhegg; Elliott Kieff
EBNA-LP associates with cellular proteins including DNA-PK and HA95.
Journal of virology 2001;75(5):2475-81.
2000: X Wu; John H J Petrini; WF Heine; David Weaver; David M Livingston; J Chen
Independence of R/M/N focus formation and the presence of intact BRCA1.
Science (New York, N.Y.) 2000;289(5476):11.
2000: X Wu; Velvizhi Ranganathan; D S Weisman; WF Heine; David N Ciccone; T B O'Neill; K E Crick; K A Pierce; William Stratton Lane; GA Rathbun; David M Livingston; David Weaver
ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response.
Nature 2000;405(6785):477-82.
2000: Surender Kharbanda; V Kumar; S Dhar; Pramod Pandey; C Chen; P Majumder; Zhi-Min Yuan; Young E Whang; W Strauss; Tej K Pandita; David Weaver; Donald Kufe
Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase.
Current biology : CB 2000;10(10):568-75.
2000: X Wu; GA Rathbun; William Stratton Lane; David Weaver; David M Livingston
Interactions of the Nijmegen breakage syndrome protein with ATM and BRCA1.
Cold Spring Harbor symposia on quantitative biology 2000;65():535-45.
1998: M F Reed; V F Liu; MH Ladha; K Ando; James D Griffin; David Weaver; Mark E Ewen
Enforced CDK4 expression in a hematopoietic cell line confers resistance to the G1 arrest induced by ionizing radiation.
Oncogene 1998;17(23):2961-71.
1998: Ajit Bharti; Stine-Kathrein Kraeft; M Gounder; Pramod Pandey; S Jin; Zhi-Min Yuan; Susan Lees-Miller; Ralph Weichselbaum; David Weaver; Lan Bo Chen; Donald Kufe; Surender Kharbanda
Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis.
Molecular and cellular biology 1998;18(11):6719-28.
1998: David Weaver
DNA repair: bacteria to humans. A conference sponsored by the Genetics Society of America, April 16-19, 1998.
Biochimica et biophysica acta 1998;1378(2):R1-9.
1998: S Kumar; Pramod Pandey; Ajit Bharti; S Jin; Ralph Weichselbaum; David Weaver; Donald Kufe; Surender Kharbanda
Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase.
The Journal of biological chemistry 1998;273(40):25654-8.
1998: Yijie Gao; Jayanta Chaudhuri; Chengming Zhu; L Davidson; David Weaver; Frederick W Alt
A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination.
Immunity 1998;9(3):367-76.
1998: David Weaver
Telomeres: moonlighting by DNA repair proteins.
Current biology : CB 1998;8(14):R492-4.
1998: S Jin; S Inoue; David Weaver
Differential etoposide sensitivity of cells deficient in the Ku and DNA-PKcs components of the DNA-dependent protein kinase.
Carcinogenesis 1998;19(6):965-71.
1997: S Jin; David Weaver
Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions.
The EMBO journal 1997;16(22):6874-85.
1997: S Jin; S Kharbanda; B Mayer; Donald Kufe; David Weaver
Binding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunit.
The Journal of biological chemistry 1997;272(40):24763-6.
1997: Y Xiao; David Weaver
Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells.
Nucleic acids research 1997;25(15):2985-91.
1997: David Weaver; F W Alt
V(D)J recombination. From RAGs to stitches.
Nature 1997;388(6641):428-9.
1997: Yansong Gu; S Jin; Yijie Gao; David Weaver; Frederick W Alt
Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(15):8076-81.
1997: Surender Kharbanda; Pramod Pandey; S Jin; S Inoue; Ajit Bharti; Zhi-Min Yuan; Ralph Weichselbaum; David Weaver; Donald Kufe
Functional interaction between DNA-PK and c-Abl in response to DNA damage.
Nature 1997;386(6626):732-5.
1997: Ralph Scully; J Chen; AW Plug; Y Xiao; David Weaver; Jean Feunteun; Terry Ashley; David M Livingston
Association of BRCA1 with Rad51 in mitotic and meiotic cells.
Cell 1997;88(2):265-75.
1997: S Jin; S Inoue; David Weaver
Functions of the DNA dependent protein kinase.
Cancer surveys 1997;29():221-61.
1996: F Liang; P J Romanienko; David Weaver; Penny Jeggo; Maria Jasin
Chromosomal double-strand break repair in Ku80-deficient cells.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):8929-33.
1996: G T Milne; S Jin; Katie Shannon; David Weaver
Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae.
Molecular and cellular biology 1996;16(8):4189-98.
1996: David Weaver
Regulation and repair of double-strand DNA breaks.
Critical reviews in eukaryotic gene expression 1996;6(4):345-75.
1995: N V Boubnov; David Weaver
scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase.
Molecular and cellular biology 1995;15(10):5700-6.
1995: David Weaver
What to do at an end: DNA double-strand-break repair.
Trends in genetics : TIG 1995;11(10):388-92.
1995: John H J Petrini; M E Walsh; C DiMare; X N Chen; julie R korenberg; David Weaver
Isolation and characterization of the human MRE11 homologue.
Genomics 1995;29(1):80-6.
1995: John H J Petrini; Y Xiao; David Weaver
DNA ligase I mediates essential functions in mammalian cells.
Molecular and cellular biology 1995;15(8):4303-8.
1995: V F Liu; N V Boubnov; David Weaver
Cell cycle checkpoints and repair of ionizing radiation damage.
Stem cells (Dayton, Ohio) 1995;13 Suppl 1():117-28.
1995: N V Boubnov; Z P Wills; David Weaver
Coding sequence composition flanking either signal element alters V(D)J recombination efficiency.
Nucleic acids research 1995;23(6):1060-7.
1995: G T Milne; T Ho; David Weaver
Modulation of Saccharomyces cerevisiae DNA double-strand break repair by SRS2 and RAD51.
Genetics 1995;139(3):1189-99.
1995: David Weaver
V(D)J recombination and double-strand break repair.
Advances in immunology 1995;58():29-85.
1994: J W Donovan; G T Milne; David Weaver
Homotypic and heterotypic protein associations control Rad51 function in double-strand break repair.
Genes & development 1994;8(21):2552-62.
1994: Satnam S Banga; K T Hall; A K Sandhu; David Weaver; Raghbir S Athwal
Complementation of V(D)J recombination defect and X-ray sensitivity of scid mouse cells by human chromosome 8.
Mutation research 1994;315(3):239-47.
1994: J E Staunton; David Weaver
scid cells efficiently integrate hairpin and linear DNA substrates.
Molecular and cellular biology 1994;14(6):3876-83.
1994: John H J Petrini; J W Donovan; C Dimare; David Weaver
Normal V(D)J coding junction formation in DNA ligase I deficiency syndromes.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(1):176-83.
1993: V F Liu; David Weaver
The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells.
Molecular and cellular biology 1993;13(12):7222-31.
1993: N V Boubnov; Z P Wills; David Weaver
V(D)J recombination coding junction formation without DNA homology: processing of coding termini.
Molecular and cellular biology 1993;13(11):6957-68.
1993: G T Milne; David Weaver
Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52.
Genes & development 1993;7(9):1755-65.
1991: John H J Petrini; K G Huwiler; David Weaver
A wild-type DNA ligase I gene is expressed in Bloom's syndrome cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7615-9.
1991: Eric A Hendrickson; V F Liu; David Weaver
Strand breaks without DNA rearrangement in V (D)J recombination.
Molecular and cellular biology 1991;11(6):3155-62.
1991: Eric A Hendrickson; X Q Qin; E A Bump; D G Schatz; M Oettinger; David Weaver
A link between double-strand break-related repair and V(D)J recombination: the scid mutation.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(10):4061-5.
1990: Eric A Hendrickson; M S Schlissel; David Weaver
Wild-type V(D)J recombination in scid pre-B cells.
Molecular and cellular biology 1990;10(10):5397-407.
1989: T Imanishi-Kari; David Weaver; David Baltimore
On the specificity of BET-1 antibody.
Cell 1989;57(4):515-6.
1989: David Weaver; E Hendrickson
The scid mutation disrupts gene rearrangement at the rejoining of coding strands.
Current topics in microbiology and immunology 1989;152():77-84.
1988: T Imanishi-Kari; M H Reis; David Weaver; David Baltimore
Altered repertoire of endogenous immunoglobulin gene expression in transgenic mice containing a rearranged mu heavy chain gene.
Cell 1988;55(4):541.
1988: Eric A Hendrickson; D G Schatz; David Weaver
The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement.
Genes & development 1988;2(7):817-29.
1987: L A Herzenberg; A M Stall; J Braun; David Weaver; David Baltimore; L A Herzenberg; R Grosschedl
Depletion of the predominant B-cell population in immunoglobulin mu heavy-chain transgenic mice.
Nature 1987;329(6134):71-3.
1987: David Weaver; David Baltimore
B lymphocyte-specific protein binding near an immunoglobulin kappa-chain gene J segment.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(6):1516-20.
1986: M F Charette; David Weaver; M L DePamphilis
Persistence of DNA synthesis arrest sites in the presence of T4 DNA polymerase and T4 gene 32, 44, 45 and 62 DNA polymerase accessory proteins.
Nucleic acids research 1986;14(8):3343-62.
1986: David Weaver; M H Reis; C Albanese; F Costantini; David Baltimore; T Imanishi-Kari
Altered repertoire of endogenous immunoglobulin gene expression in transgenic mice containing a rearranged mu heavy chain gene.
Cell 1986;45(2):247-59.
1985: David Weaver; F Costantini; T Imanishi-Kari; David Baltimore
A transgenic immunoglobulin mu gene prevents rearrangement of endogenous genes.
Cell 1985;42(1):117-27.
1985: David Weaver; S C Fields-Berry; M L DePamphilis
The termination region for SV40 DNA replication directs the mode of separation for the two sibling molecules.
Cell 1985;41(2):565-75.
1985: David Baltimore; R Grosschedl; David Weaver; F Costantini; T Imanishi-Kari
Studies of immunodifferentiation using transgenic mice.
Cold Spring Harbor symposia on quantitative biology 1985;50():417-20.
1984: David Weaver; M L DePamphilis
The role of palindromic and non-palindromic sequences in arresting DNA synthesis in vitro and in vivo.
Journal of molecular biology 1984;180(4):961-86.
1984: R Grosschedl; David Weaver; David Baltimore; F Costantini
Introduction of a mu immunoglobulin gene into the mouse germ line: specific expression in lymphoid cells and synthesis of functional antibody.
Cell 1984;38(3):647-58.
1983: C G Pritchard; David Weaver; E F Baril; M L DePamphilis
DNA polymerase alpha cofactors C1C2 function as primer recognition proteins.
The Journal of biological chemistry 1983;258(16):9810-9.
1982: David Weaver; M L DePamphilis
Specific sequences in native DNA that arrest synthesis by DNA polymerase alpha.
The Journal of biological chemistry 1982;257(4):2075-86.