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Jeff Kiefer

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Sungwon Jung; Jeff Kiefer; Michael Berens; Michael Bittner; Daniel Von Hoff; Michael Verdicchio; Seungchan Kim
Learning contextual gene set interaction networks of cancer with condition specificity.
Toni Farley; Jeff Kiefer; Preston Lee; Jeffrey M. Trent; Daniel Von Hoff; Charles Colbourn; Spyro Mousses
The BioIntelligence Framework: a new computational platform for biomedical knowledge computing.
Lifang Xie; Hongwei H Yin; Yu Zhao; Michelle Kassner; Jeff Kiefer; Spyro Mousses; Ruben M Munoz; Qiang Q Que; Daniel D Von Hoff; Haiyong Han
Kinome-wide siRNA screening identifies molecular targets mediating the sensitivity of pancreatic cancer cells to Aurora kinase inhibitors.

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All Publications

2013: Sungwon Jung; Jeff Kiefer; Michael Berens; Michael Bittner; Daniel Von Hoff; Michael Verdicchio; Seungchan Kim
Learning contextual gene set interaction networks of cancer with condition specificity.
BMC genomics 2013;14():110.
2013: Toni Farley; Jeff Kiefer; Preston Lee; Jeffrey M. Trent; Daniel Von Hoff; Charles Colbourn; Spyro Mousses
The BioIntelligence Framework: a new computational platform for biomedical knowledge computing.
Journal of the American Medical Informatics Association : JAMIA 2013;20(1):128-33.
2012: Lifang Xie; Hongwei H Yin; Yu Zhao; Michelle Kassner; Jeff Kiefer; Spyro Mousses; Ruben M Munoz; Qiang Q Que; Daniel D Von Hoff; Haiyong Han
Kinome-wide siRNA screening identifies molecular targets mediating the sensitivity of pancreatic cancer cells to Aurora kinase inhibitors.
Biochemical pharmacology 2012;83(4):452-61.
2011: Christian Ruiz; Michael Shen; Jeffrey M. Trent; Daniel Von Hoff; Tobias Zellweger; Lukas Bubendorf; John D Carpten; Micheal J Demeure; Lisa Evers; Tara Holley; Michael A Hollingsworth; Jeff Kiefer; Elizabeth Lenkiewicz; Spyro Mousses; Donna Prunkard; Peter S Rabinovitch; Alex Robeson; Michael T Barrett
Advancing a clinically relevant perspective of the clonal nature of cancer.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(29):12054-9.
2011: Frederick L Baehner; Mark Lee; Micheal J Demeure; Kimberly J Bussey; Jeff Kiefer; Michael T Barrett
Genomic signatures of cancer: basis for individualized risk assessment, selective staging and therapy.
Journal of surgical oncology 2011;103(6):563-73.
2010: Shilpi Arora; Christian Beaudry; Kristen M Bisanz; Chao Sima; Jeff Kiefer; David Azorsa
A high-content RNAi-screening assay to identify modulators of cholesterol accumulation in Niemann-Pick type C cells.
Assay and drug development technologies 2010;8(3):295-320.
2010: Ofer Eidelman; Catherine Jozwik; Wei Huang; Meera Srivastava; Stephen W Rothwell; David M Jacobowitz; Xiaoduo Ji; Xiuying Zhang; William B Guggino; Jerry Wright; Jeff Kiefer; Cara Olsen; Nima Adimi; Gregory P Mueller; Harvey B Pollard
Gender dependence for a subset of the low-abundance signaling proteome in human platelets.
Human genomics and proteomics : HGP 2010;2010():164906.
2009: Jeff Kiefer; Holly Yin; Qiang Q Que; Spyro Mousses
High-throughput siRNA screening as a method of perturbation of biological systems and identification of targeted pathways coupled with compound screening.
Methods in molecular biology (Clifton, N.J.) 2009;563():275-87.
2009: David Azorsa; Irma M Gonzales; Gargi D Basu; Ashish Choudhary; Shilpi Arora; Kristen M Bisanz; Jeff Kiefer; Meredith C Henderson; Jeffrey M. Trent; Daniel Von Hoff; Spyro Mousses
Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer.
Journal of translational medicine 2009;7():43.
2008: Spyro Mousses; Jeff Kiefer; Daniel Von Hoff; Jeffrey M. Trent
Using biointelligence to search the cancer genome: an epistemological perspective on knowledge recovery strategies to enable precision medical genomics.
Oncogene 2008;27 Suppl 2():S58-66.
2008: Gargi D Basu; David Azorsa; Jeff Kiefer; Angela M Rojas; Sukru Tuzmen; Michael T Barrett; Jeffrey M. Trent; Olli Kallioniemi; Spyro Mousses
Functional evidence implicating S100P in prostate cancer progression.
International journal of cancer. Journal international du cancer 2008;123(2):330-9.
2008: Hamdi Jarjanazi; Jeff Kiefer; Sevtap Savas; Laurent Briollais; Sukru Tuzmen; Noel Aquino Pabalan; Irada Ibrahim-Zada; Spyro Mousses; Hilmi Ozcelik
Discovery of genetic profiles impacting response to chemotherapy: application to gemcitabine.
Human mutation 2008;29(4):461-7.
2007: Sukru Tuzmen; Jeff Kiefer; Spyro Mousses
Validation of short interfering RNA knockdowns by quantitative real-time PCR.
Methods in molecular biology (Clifton, N.J.) 2007;353():177-203.
2006: Ilsa Coleman; Jeff Kiefer; Lisha G Brown; Tiffany E Pitts; Peter S Nelson; Kristen D Brubaker; Robert L Vessella; Eva Corey
Inhibition of androgen-independent prostate cancer by estrogenic compounds is associated with increased expression of immune-related genes.
Neoplasia (New York, N.Y.) 2006;8(10):862-78.
2005: Alessandro Lugli; Hanspeter Spichtin; Robert Maurer; Martina Mirlacher; Jeff Kiefer; Pia Huusko; David Azorsa; Luigi Terracciano; Guido Sauter; Olli Kallioniemi; Spyro Mousses; Luigi Tornillo
EphB2 expression across 138 human tumor types in a tissue microarray: high levels of expression in gastrointestinal cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(18):6450-8.
2005: Eva Corey; Lisha G Brown; Jeff Kiefer; Janna E Quinn; Tiffany E M Pitts; Julie M Blair; Robert L Vessella
Osteoprotegerin in prostate cancer bone metastasis.
Cancer research 2005;65(5):1710-8.
2004: Pia Huusko; Damaris Ponciano-Jackson; Maija Wolf; Jeff Kiefer; David Azorsa; Sukru Tuzmen; Don Weaver; Christiane Robbins; Tracy Y Moses; Minna Allinen; Sampsa Hautaniemi; Yidong Chen; Abdel G Elkahloun; Mark Basik; G Steven Bova; Lukas Bubendorf; Alessandro Lugli; Guido Sauter; Johanna Schleutker; Hilmi Ozcelik; Sabine Elowe; Tony Pawson; Jeffrey M. Trent; John D Carpten; Olli Kallioniemi; Spyro Mousses
Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer.
Nature genetics 2004;36(9):979-83.
2004: Jeff Kiefer; Robert L Vessella; Janna E Quinn; Austin M Odman; Jian Zhang; Evan T Keller; Paul J Kostenuik; Colin R Dunstan; Eva Corey
The effect of osteoprotegerin administration on the intra-tibial growth of the osteoblastic LuCaP 23.1 prostate cancer xenograft.
Clinical & experimental metastasis 2004;21(5):381-7.
2004: Jeff Kiefer; Angela Alexander; Mary C Farach-Carson
Type I collagen-mediated changes in gene expression and function of prostate cancer cells.
Cancer treatment and research 2004;118():101-24.
2001: Jeff Kiefer; M C Farach-Carson
Type I collagen-mediated proliferation of PC3 prostate carcinoma cell line: implications for enhanced growth in the bone microenvironment.
Matrix biology : journal of the International Society for Matrix Biology 2001;20(7):429-37.
1999: George N Thalmann; Robert A Sikes; R E Devoll; Jeff Kiefer; Regula Markwalder; Irena Klima; C M Farach-Carson; Urs E Studer; Leland W K Chung
Osteopontin: possible role in prostate cancer progression.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(8):2271-7.
1995: A Fernandez; Jeff Kiefer; L Fosdick; David J McConkey
Oxygen radical production and thiol depletion are required for Ca(2+)-mediated endogenous endonuclease activation in apoptotic thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(11):5133-9.
1995: Jeff Kiefer; S Okret; M Jondal; David J McConkey
Functional glucocorticoid receptor expression is required for cAMP-mediated apoptosis in a human leukemic T cell line.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(10):4525-8.
1995: N Neamati; A Fernandez; S Wright; Jeff Kiefer; David J McConkey
Degradation of lamin B1 precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(8):3788-95.