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Ruud van Gurp

Research Profile

Disorders

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Ad J M Gillis; K Biermann; S Cribbes; Astrid Ferlinz; J Wolter Oosterhuis; M Shannon; hans stoop; E Swartzman; Ruud van Gurp; Leendert H J Looijenga
Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis.
Hendrik Wermann; hans stoop; Ad J M Gillis; Friedemann Honecker; Ruud van Gurp; Ole Ammerpohl; Julia Richter; J Wolter Oosterhuis; Carsten Bokemeyer; Leendert H J Looijenga
Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance.
Jeroen de Jong; hans stoop; Ad J M Gillis; Ruud van Gurp; Gert-Jan M van de Geijn; M de Boer; Remko Hersmus; Philippa Saunders; R A Anderson; J Wolter Oosterhuis; Leendert H J Looijenga
Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications.

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All Publications

2011: Ad J M Gillis; K Biermann; S Cribbes; Astrid Ferlinz; J Wolter Oosterhuis; M Shannon; hans stoop; E Swartzman; Ruud van Gurp; Leendert H J Looijenga
Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis.
International journal of andrology 2011;34(4 Pt 2):e160-74.
2010: Hendrik Wermann; hans stoop; Ad J M Gillis; Friedemann Honecker; Ruud van Gurp; Ole Ammerpohl; Julia Richter; J Wolter Oosterhuis; Carsten Bokemeyer; Leendert H J Looijenga
Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance.
The Journal of pathology 2010;221(4):433-42.
2008: Jeroen de Jong; hans stoop; Ad J M Gillis; Ruud van Gurp; Gert-Jan M van de Geijn; M de Boer; Remko Hersmus; Philippa Saunders; R A Anderson; J Wolter Oosterhuis; Leendert H J Looijenga
Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications.
The Journal of pathology 2008;215(1):21-30.
2008: Jeroen de Jong; hans stoop; Ad J M Gillis; Remko Hersmus; Ruud van Gurp; Gert-Jan M van de Geijn; Ellen van Drunen; Berna Beverloo; Dominik Schneider; Jon K Sherlock; John Baeten; Sohei Kitazawa; Everardus J J van Zoelen; Kees E P van Roozendaal; J Wolter Oosterhuis; Leendert H J Looijenga
Further characterization of the first seminoma cell line TCam-2.
Genes, chromosomes & cancer 2008;47(3):185-96.
2007: Jeroen de Jong; hans stoop; Ad J M Gillis; Ruud van Gurp; Ellen van Drunen; Berna Beverloo; Yun-Fai Chris Lau; Dominik Schneider; Jon K Sherlock; John Baeten; Shingo Hatakeyama; Chikara Ohyama; J Wolter Oosterhuis; Leendert H J Looijenga
JKT-1 is not a human seminoma cell line.
International journal of andrology 2007;30(4):350-65.
2007: Martine Cools; Marjan Boter; Ruud van Gurp; hans stoop; Pino Poddighe; Yun-Fai Chris Lau; Stenvert L S Drop; Katja P Wolffenbuttel; Leendert H J Looijenga
Impact of the Y-containing cell line on histological differentiation patterns in dysgenetic gonads.
Clinical endocrinology 2007;67(2):184-92.
2006: Paul C M S Verhagen; Petra W van Duijn; Karin G Hermans; Leendert H J Looijenga; Ruud van Gurp; hans stoop; Theo Van der Kwast; Jan Trapman
The PTEN gene in locally progressive prostate cancer is preferentially inactivated by bi-allelic gene deletion.
The Journal of pathology 2006;208(5):699-707.
2006: Leendert H J Looijenga; Remko Hersmus; Ad J M Gillis; Rolph Pfundt; hans stoop; Ruud van Gurp; Joris Veltman; Berna Beverloo; Ellen van Drunen; Ad Geurts van Kessel; Renee Reijo Pera; Dominik Schneider; Brenda Summersgill; Janet Shipley; Alan McIntyre; Peter van der Spek; Eric F P M Schoenmakers; J Wolter Oosterhuis
Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene.
Cancer research 2006;66(1):290-302.
2006: Graham Bignell; Raffaella Smith; Chris Hunter; Philip Stephens; Helen Davies; Chris Greenman; Jon Teague; Adam Butler; Sarah Edkins; Claire Stevens; Sarah O'Meara; Adrian Parker; Tim Avis; Syd Barthorpe; Lisa Brackenbury; Gemma Buck; Jody Clements; Jennifer Cole; Ed Dicks; Ken Edwards; Simon Forbes; Matthew Gorton; Kristian Gray; Kelly Halliday; Rachel Harrison; Katy Hills; Jonathon Hinton; David Jones; Vivienne Kosmidou; Ross Laman; Richard Lugg; Andrew Menzies; Janet Perry; Robert Petty; Keiran Raine; Rebecca Shepherd; Alexandra Small; Helen Solomon; Yvonne Stephens; Calli Tofts; Jennifer Varian; Anthony Webb; Sofie West; Sara Caroline Widaa; Andy Yates; Ad J M Gillis; hans stoop; Ruud van Gurp; J Wolter Oosterhuis; Leendert H J Looijenga; P Andrew Futreal; Richard Wooster; Michael R Stratton
Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults.
Genes, chromosomes & cancer 2006;45(1):42-6.
2005: Alan McIntyre; Brenda Summersgill; Beata Grygalewicz; Ad J M Gillis; J Stoop; Ruud van Gurp; Nening Dennis; Cyril Fisher; Robert A Huddart; Colin Cooper; Jeremy Clark; J Wolter Oosterhuis; Leendert H J Looijenga; Janet Shipley
Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults.
Cancer research 2005;65(18):8085-9.
2003: Leendert H J Looijenga; Hubert P J C de Leeuw; Monique van Oorschot; Ruud van Gurp; hans stoop; Ad J M Gillis; Carlos A de Gouveia Brazao; R F A Weber; Wim J Kirkels; Thamar B van Dijk; Marieke von Lindern; Peter J M Valk; Geczy Lajos; Edit Olah; Jahn M Nesland; Sophie D Fosså; J Wolter Oosterhuis
Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumors.
Cancer research 2003;63(22):7674-8.
2003: Gaetano Zafarana; Beata Grygalewicz; Ad J M Gillis; Lisenka E L M Vissers; Walter van de Vliet; Ruud van Gurp; hans stoop; Maria Debiec-Rychter; J Wolter Oosterhuis; Ad Geurts van Kessel; Eric F P M Schoenmakers; Leendert H J Looijenga; Joris Veltman
12p-amplicon structure analysis in testicular germ cell tumors of adolescents and adults by array CGH.
Oncogene 2003;22(48):7695-701.
2003: Sandrine Rodriguez; Osman Jafer; H Goker; Brenda Summersgill; Gaetano Zafarana; Ad J M Gillis; Ruud van Gurp; J Wolter Oosterhuis; Yong-Jie Lu; Robert A Huddart; C S Cooper; Jeremy Clark; Leendert H J Looijenga; Janet Shipley
Expression profile of genes from 12p in testicular germ cell tumors of adolescents and adults associated with i(12p) and amplification at 12p11.2-p12.1.
Oncogene 2003;22(12):1880-91.
2003: Leendert H J Looijenga; Gaetano Zafarana; Beata Grygalewicz; Brenda Summersgill; Maria Debiec-Rychter; Joris Veltman; Eric F P M Schoenmakers; Sandrine Rodriguez; Osman Jafer; Jeremy Clark; Ad Geurts van Kessel; Janet Shipley; Ruud van Gurp; Ad J M Gillis; J Wolter Oosterhuis
Role of gain of 12p in germ cell tumour development.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):161-71; discussion 172-3.
2002: Camilla Palumbo; Kees E P van Roozendaal; Ad J M Gillis; Ruud van Gurp; Hannie de Munnik; J Wolter Oosterhuis; Everardus J J van Zoelen; Leendert H J Looijenga
Expression of the PDGF alpha-receptor 1.5 kb transcript, OCT-4, and c-KIT in human normal and malignant tissues. Implications for the early diagnosis of testicular germ cell tumours and for our understanding of regulatory mechanisms.
The Journal of pathology 2002;196(4):467-77.
2002: Gaetano Zafarana; Ad J M Gillis; Ruud van Gurp; Per Olsson; Fons Elstrodt; hans stoop; José Luis Millán; J Wolter Oosterhuis; Leendert H J Looijenga
Coamplification of DAD-R, SOX5, and EKI1 in human testicular seminomas, with specific overexpression of DAD-R, correlates with reduced levels of apoptosis and earlier clinical manifestation.
Cancer research 2002;62(6):1822-31.
2001: hans stoop; Ruud van Gurp; Ronald R de Krijger; A Geurts van Kessel; B Köberle; Wolter Oosterhuis; Leendert H J Looijenga
Reactivity of germ cell maturation stage-specific markers in spermatocytic seminoma: diagnostic and etiological implications.
Laboratory investigation; a journal of technical methods and pathology 2001;81(7):919-28.
2000: Carla Rosenberg; Ruud van Gurp; Eric Geelen; J Wolter Oosterhuis; Leendert H J Looijenga
Overrepresentation of the short arm of chromosome 12 is related to invasive growth of human testicular seminomas and nonseminomas.
Oncogene 2000;19(51):5858-62.
2000: H Roelofs; MC Mostert; K Pompe; Gaetano Zafarana; M van Oorschot; Ruud van Gurp; Ad J M Gillis; hans stoop; Berna Beverloo; J Wolter Oosterhuis; Carsten Bokemeyer; Leendert H J Looijenga
Restricted 12p amplification and RAS mutation in human germ cell tumors of the adult testis.
The American journal of pathology 2000;157(4):1155-66.
2000: Daan Noort; Albert G Hulst; Alex Fidder; Ruud van Gurp; L P A de Jong; Hendrik P Benschop
In vitro adduct formation of phosgene with albumin and hemoglobin in human blood.
Chemical research in toxicology 2000;13(8):719-26.
2000: Leendert H J Looijenga; Carla Rosenberg; Ruud van Gurp; Eric Geelen; Jannie van Echten-Arends; Bauke de Jong; MC Mostert; J Wolter Oosterhuis
Comparative genomic hybridization of microdissected samples from different stages in the development of a seminoma and a non-seminoma.
The Journal of pathology 2000;191(2):187-92.
1999: E M van Schothorst; S Mohkamsing; Ruud van Gurp; J Wolter Oosterhuis; P T van der Saag; Leendert H J Looijenga
Lack of Bcl10 mutations in testicular germ cell tumours and derived cell lines.
British journal of cancer 1999;80(10):1571-4.
1998: H Roelofs; Ruud van Gurp; J Wolter Oosterhuis; Leendert H J Looijenga
Detection of human endogenous retrovirus type K-specific transcripts in testicular parenchyma and testicular germ cell tumors of adolescents and adults: clinical and biological implications.
The American journal of pathology 1998;153(4):1277-82.
1998: AA Caricasole; Ron van Schaik; Laura M Zeinstra; CD Wierikx; Ruud van Gurp; M van den Pol; Leendert H J Looijenga; J Wolter Oosterhuis; M F Pera; A Ward; D de Bruijn; Piet Kramer; Frank de Jong; AJ van den Eijnden-van Raaij
Human growth-differentiation factor 3 (hGDF3): developmental regulation in human teratocarcinoma cell lines and expression in primary testicular germ cell tumours.
Oncogene 1998;16(1):95-103.
1998: Leendert H J Looijenga; AJ Verkerk; MC Dekker; Ruud van Gurp; Ad J M Gillis; J Wolter Oosterhuis
Genomic imprinting in testicular germ cell tumours.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1998;106(1):187-95; discussion 196-7.
1997: Leendert H J Looijenga; Ad J M Gillis; Ruud van Gurp; AJ Verkerk; J Wolter Oosterhuis
X inactivation in human testicular tumors. XIST expression and androgen receptor methylation status.
The American journal of pathology 1997;151(2):581-90.
1997: AJ Verkerk; Ilana Ariel; MC Dekker; T Schneider; Ruud van Gurp; N de Groot; Ad J M Gillis; J Wolter Oosterhuis; Abraham Hochberg; Leendert H J Looijenga
Unique expression patterns of H19 in human testicular cancers of different etiology.
Oncogene 1997;14(1):95-107.
1997: Ad J M Gillis; AJ Verkerk; MC Dekker; Ruud van Gurp; J Wolter Oosterhuis; Leendert H J Looijenga
Methylation similarities of two CpG sites within exon 5 of human H19 between normal tissues and testicular germ cell tumours of adolescents and adults, without correlation with allelic and total level of expression.
British journal of cancer 1997;76(6):725-33.
1995: Jannie van Echten; Ruud van Gurp; M Stoepker; Leendert H J Looijenga; J de Jong; W Oosterhuis
Cytogenetic evidence that carcinoma in situ is the precursor lesion for invasive testicular germ cell tumors.
Cancer genetics and cytogenetics 1995;85(2):133-7.
1994: Ad J M Gillis; J Wolter Oosterhuis; M E Schipper; E J Barten; R van Berlo; Ruud van Gurp; M Abraham; G F Saunders; Leendert H J Looijenga
Origin and biology of a testicular Wilms' tumor.
Genes, chromosomes & cancer 1994;11(2):126-35.
1994: Ruud van Gurp; J Wolter Oosterhuis; Vera Kalscheuer; E C Mariman; Leendert H J Looijenga
Biallelic expression of the H19 and IGF2 genes in human testicular germ cell tumors.
Journal of the National Cancer Institute 1994;86(14):1070-5.
1994: A C Lambrechts; Lambert C J Dorssers; P E Hupkes; Ruud van Gurp; R Baumgarten; A Hagemeijer; M B van 't Veer; Ivo P Touw
Genomic organization of the translocations (8;14) and (14;18) in a new lymphoma cell line.
Leukemia 1994;8(7):1164-71.
1992: Ivo P Touw; Ruud van Gurp; P Schipper; Ton van Agthoven; Bob Löwenberg
Introduction of the human interleukin-6 (IL-6) receptor in murine IL-3-dependent hematopoietic cells restores responsiveness to IL-6.
Blood 1992;79(11):2867-72.
1991: V Santini; P Colombat; Ruud Delwel; Ruud van Gurp; Ivo P Touw; Bob Löwenberg
Induction of granulocytic maturation in acute myeloid leukemia by G-CSF and retinoic acid.
Leukemia research 1991;15(5):341-50.
1990: Ivo P Touw; K Pouwels; Ton van Agthoven; Ruud van Gurp; Ruud Delwel; A Hagemeijer; Karel Hählen; Bob Löwenberg
Role of interleukin-7 in the growth of acute lymphoblastic leukemia.
Bone marrow transplantation 1990;6 Suppl 1():36-8.
1990: Ivo P Touw; K Pouwels; Ton van Agthoven; Ruud van Gurp; L Budel; H Hoogerbrugge; Ruud Delwel; R Goodwin; A Namen; Bob Löwenberg
Interleukin-7 is a growth factor of precursor B and T acute lymphoblastic leukemia.
Blood 1990;75(11):2097-101.
1989: A Molendijk; Ruud van Gurp; A C Knulst; Robbert Benner
MHC- and Igh-unrestricted interaction between L3T4+, Lyt-2- Ts inducer cells and L3T4-, Lyt-2+ Ts effector cells is required for T cell-dependent suppression of DTH to histocompatibility antigens.
Immunobiology 1989;179(1):56-67.
1989: A Molendijk; L M Hussaarts-Odijk; Ruud van Gurp; H de Ruiter; Robbert Benner
Suppression of antigraft immunity by preimmunization. V. Characterization of suppressor T memory cells.
Immunobiology 1989;178(4-5):351-60.
1988: Ruud Delwel; Ruud van Gurp; Fredrik J Bot; Ivo P Touw; Bob Löwenberg
Phenotyping of acute myelocytic leukemia (AML) progenitors: an approach for tracing minimal numbers of AML cells among normal bone marrow.
Leukemia 1988;2(12):814-9.
1988: Ruud van Gurp
Critical analysis of alternate retrograde filling techniques.
Journal - Connecticut State Dental Association 1988;62(3):121-4.
1988: A Molendijk; A C Knulst; Ruud van Gurp; A van Oudenaren; Robbert Benner
Lipopolysaccharide-induced suppression of graft-versus-host reactivity in mice.
Immunobiology 1988;177(4-5):371-81.
1988: A Molendijk; H Bril; L M Hussaarts-Odijk; Ruud van Gurp; Robbert Benner
Generation of suppressor T cells after local immunization with histocompatibility antigens.
Cellular immunology 1988;113(2):480-93.
1988: A Molendijk; H Bril; L M Hussaarts-Odijk; Ruud van Gurp; Robbert Benner
Lipopolysaccharide-induced suppression of DTH-reactivity to histocompatibility antigens. I. Kinetic aspects and specificity.
Immunobiology 1988;176(3):255-71.
1987: A Molendijk; Ruud van Gurp; I G Donselaar; Robbert Benner
Suppression of delayed-type hypersensitivity to histocompatibility antigens by ultraviolet radiation.
Immunology 1987;62(2):299-305.
1987: A Molendijk; Ruud van Gurp; Robbert Benner
Evidence for an inducer-suppressor T cell in the regulation of DTH to alloantigens.
Transplantation proceedings 1987;19(5):4261-4.
1987: A Molendijk; Ruud van Gurp; Robbert Benner
Suppressor T cells induced by UV-B irradiation suppress DTH to alloantigens.
Transplantation proceedings 1987;19(5):4258-60.
1987: A Molendijk; Ruud van Gurp; A van Oudenaren; Robbert Benner
Induction and suppression of graft-versus-host reactivity in B6.C-H-2 mutant mice.
Transplantation proceedings 1987;19(1 Pt 3):2698-9.