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Ed Buurman

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Suzanne S Stokes; Adam B Shapiro; Robert Albert; Beth Andrews; Ed T Buurman; Oluyinka M Green; Andrew R McKenzie; Ludovic R Otterbein
Inhibitors of the acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridylyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU). Part 2: Optimization of physical properties leading to antibacterial aryl sulfonamides.
Ed T Buurman; Melinda A Foulk; Ning Gao; Valerie A Laganas; David C McKinney; Demetri T Moustakas; Jonathan A Rose; Adam B Shapiro; Paul R Fleming
Novel rapidly diversifiable antimicrobial RNA polymerase switch region inhibitors with confirmed mode of action in Haemophilus influenzae.
Hector Mora-Montes; Steven Bates; Mihai G Netea; Luis Castillo; Alexandra Brand; Ed T Buurman; Diana F Díaz-Jiménez; Bart Jan Kullberg; Alistair J P Brown; Frank C Odds; Neil A R Gow
A multifunctional mannosyltransferase family in Candida albicans determines cell wall mannan structure and host-fungus interactions.

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2012: Suzanne S Stokes; Adam B Shapiro; Robert Albert; Beth Andrews; Ed T Buurman; Oluyinka M Green; Andrew R McKenzie; Ludovic R Otterbein
Inhibitors of the acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridylyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU). Part 2: Optimization of physical properties leading to antibacterial aryl sulfonamides.
Bioorganic & medicinal chemistry letters 2012;22(23):7019-23.
2012: Ed T Buurman; Melinda A Foulk; Ning Gao; Valerie A Laganas; David C McKinney; Demetri T Moustakas; Jonathan A Rose; Adam B Shapiro; Paul R Fleming
Novel rapidly diversifiable antimicrobial RNA polymerase switch region inhibitors with confirmed mode of action in Haemophilus influenzae.
Journal of bacteriology 2012;194(20):5504-12.
2010: Hector Mora-Montes; Steven Bates; Mihai G Netea; Luis Castillo; Alexandra Brand; Ed T Buurman; Diana F Díaz-Jiménez; Bart Jan Kullberg; Alistair J P Brown; Frank C Odds; Neil A R Gow
A multifunctional mannosyltransferase family in Candida albicans determines cell wall mannan structure and host-fungus interactions.
The Journal of biological chemistry 2010;285(16):12087-95.
2006: Mihai G Netea; Neil A R Gow; Carol A Munro; Steven Bates; Claire Collins; Gerben Ferwerda; Richard P Hobson; Gwyneth Bertram; H Bleddyn Hughes; Trees Jansen; Liesbeth Jacobs; Ed T Buurman; Karlijn Gijzen; David L Williams; Ruurd Torensma; Alistair McKinnon; Donna MacCallum; Frank C Odds; Jos W M van der Meer; Alistair J P Brown; Bart Jan Kullberg
Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors.
The Journal of clinical investigation 2006;116(6):1642-50.
2006: Ed T Buurman; Kenneth D Johnson; Roxanne K Kelly; Kathy MacCormack
Different modes of action of naphthyridones in gram-positive and gram-negative bacteria.
Antimicrobial agents and chemotherapy 2006;50(1):385-7.
2005: Steven Bates; Donna MacCallum; Gwyneth Bertram; Carol A Munro; H Bleddyn Hughes; Ed T Buurman; Alistair J P Brown; Frank C Odds; Neil A R Gow
Candida albicans Pmr1p, a secretory pathway P-type Ca2+/Mn2+-ATPase, is required for glycosylation and virulence.
The Journal of biological chemistry 2005;280(24):23408-15.
2005: Ed T Buurman; Beth Andrews; April E Blodgett; Jini S Chavda; Norbert F Schnell
Utilization of target-specific, hypersensitive strains of Saccharomyces cerevisiae to determine the mode of action of antifungal compounds.
Antimicrobial agents and chemotherapy 2005;49(6):2558-60.
2005: Carol A Munro; Steven Bates; Ed T Buurman; H Bleddyn Hughes; Donna MacCallum; Gwyneth Bertram; Abdelmadjid Atrih; Michael A J Ferguson; Judith M Bain; Alexandra Brand; Suzanne Hamilton; Caroline Westwater; Lynn M Thomson; Alistair J P Brown; Frank C Odds; Neil A R Gow
Mnt1p and Mnt2p of Candida albicans are partially redundant alpha-1,2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence.
The Journal of biological chemistry 2005;280(2):1051-60.
2004: Ed T Buurman; Debra McLaggan; Josef Naprstek; Wolfgang Epstein
Multiple paths for nonphysiological transport of K+ in Escherichia coli.
Journal of bacteriology 2004;186(13):4238-45.
2004: Ed T Buurman; April E Blodgett; Kenneth G Hull; Daniel Carcanague
Pyridines and pyrimidines mediating activity against an efflux-negative strain of Candida albicans through putative inhibition of lanosterol demethylase.
Antimicrobial agents and chemotherapy 2004;48(1):313-8.
2002: Ed T Buurman; Weidong Jiang; Melissa McCoy; Devron Averett; Craig M Thompson; C Richard Wobbe
Validation of Cdc68p as a novel antifungal target.
Archives of microbiology 2002;178(6):428-36.
2001: Ed T Buurman; J D Bradley; C E Donnelly; J B Moore; J M Healy; Devron Averett; C M Thompson; C R Wobbe
Regulation of both gene expression and protein stability provides genetically assisted target evaluation (GATE) for microbial target validation.
Pharmacogenomics 2001;2(2):95-106.
1999: Neil A R Gow; Steven Bates; Alistair J P Brown; Ed T Buurman; Lynn M Thomson; Caroline Westwater
Candida cell wall mannosylation: importance in host-fungus interaction and potential as a target for the development of antifungal drugs.
Biochemical Society transactions 1999;27(4):512-6.
1998: Ed T Buurman; Caroline Westwater; B Hube; Alistair J P Brown; Frank C Odds; Neil A R Gow
Molecular analysis of CaMnt1p, a mannosyl transferase important for adhesion and virulence of Candida albicans.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7670-5.
1998: Gustavo Niño-Vega; Ed T Buurman; Graham W Gooday; Gioconda San-Blas; Neil A R Gow
Molecular cloning and sequencing of a chitin synthase gene (CHS2) of Paracoccidioides brasiliensis.
Yeast (Chichester, England) 1998;14(2):181-7.