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Bhagirath Singh

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TOP 3
Kelly L Summers; Bhagirath Singh
Research highlights: highlights from the latest articles in immunotherapy.
Bhagirath Singh; Enayat Nikoopour; John F Elliott; Katrina Huszarik; Anthony M Jevnikar
Immunomodulation and regeneration of islet Beta cells by cytokines in autoimmune type 1 diabetes.
Enayat Nikoopour; Christian Sandrock; Katrina Huszarik; Olga Krougly; Edwin Lee-Chan; Emma L Masteller; Jeffrey A Bluestone; Bhagirath Singh
Cutting edge: vasostatin-1-derived peptide ChgA29-42 is an antigenic epitope of diabetogenic BDC2.5 T cells in nonobese diabetic mice.

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All Publications

2012: Kelly L Summers; Bhagirath Singh
Research highlights: highlights from the latest articles in immunotherapy.
Immunotherapy 2012;4(4):363-4.
2011: Bhagirath Singh; Enayat Nikoopour; John F Elliott; Katrina Huszarik; Anthony M Jevnikar
Immunomodulation and regeneration of islet Beta cells by cytokines in autoimmune type 1 diabetes.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2011;31(10):711-9.
2011: Enayat Nikoopour; Christian Sandrock; Katrina Huszarik; Olga Krougly; Edwin Lee-Chan; Emma L Masteller; Jeffrey A Bluestone; Bhagirath Singh
Cutting edge: vasostatin-1-derived peptide ChgA29-42 is an antigenic epitope of diabetogenic BDC2.5 T cells in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(7):3831-5.
2010: Katrina Huszarik; Benjamin Wright; Christina Keller; Enayat Nikoopour; Olga Krougly; Edwin Lee-Chan; Hui-Yu Qin; Mark J Cameron; Werner K Gurr; David J Hill; Robert S Sherwin; David J Kelvin; Bhagirath Singh
Adjuvant immunotherapy increases beta cell regenerative factor Reg2 in the pancreas of diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):5120-9.
2010: Patrick Kilgannon; Zuzana Novak; Arun Fotedar; Bhagirath Singh
Junctional diversity prevents negative selection of an antigen-specific T cell repertoire.
Molecular immunology 2010;47(5):1154-60.
2009: Xiaoxia Zhang; Mawadda Alnaeeli; Bhagirath Singh; Yen-Tung A Teng
Involvement of SOCS3 in regulation of CD11c+ dendritic cell-derived osteoclastogenesis and severe alveolar bone loss.
Infection and immunity 2009;77(5):2000-9.
2009: Michelle B French; Mark B Loeb; Carol Richardson; Bhagirath Singh
Research preparedness paves the way to respond to pandemic H1N1 2009 influenza virus.
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie médicale / AMMI Canada 2009;20(3):63-e66.
2008: Tracey A Stephens; Enayat Nikoopour; Beverley Rider; Matilde Leon-Ponte; Thu A Chau; mikolajczak sebastian; Pratibha Chaturvedi; Edwin Lee-Chan; Richard A Flavell; S M Mansour Haeryfar; Joaquín Madrenas; Bhagirath Singh
Dendritic cell differentiation induced by a self-peptide derived from apolipoprotein E.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):6859-71.
2008: Enayat Nikoopour; Jordan Ari Schwartz; Bhagirath Singh
Therapeutic benefits of regulating inflammation in autoimmunity.
Inflammation & allergy drug targets 2008;7(3):203-10.
2008: Annette M Marleau; Kelly L Summers; Bhagirath Singh
Differential contributions of APC subsets to T cell activation in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(8):5235-49.
2008: Rinee Mukherjee; Pratibha Chaturvedi; Edwin Lee-Chan; Bhagirath Singh
Exogenous CLIP localizes into endocytic compartment of cells upon internalization: implications for antigen presentation by MHC class II molecules.
Molecular immunology 2008;45(8):2166-76.
2007: Leila Bocksch; Beverley Rider; Tracey Stephens; Erbin Dai; Liying Liu; Hong Diao; Kasinath Viswanathan; Ganesh Munuswamy-Ramanujam; Bhagirath Singh; Alexandra Lucas
C-terminal apolipoprotein E-derived peptide, Ep1.B, displays anti-atherogenic activity.
Atherosclerosis 2007;194(1):116-24.
2006: Kelly L Summers; Annette M Marleau; Jeffrey L Mahon; Ruth McManus; Irene Hramiak; Bhagirath Singh
Reduced IFN-alpha secretion by blood dendritic cells in human diabetes.
Clinical immunology (Orlando, Fla.) 2006;121(1):81-9.
2006: Hui-Yu Qin; Rinee Mukherjee; Edwin Lee-Chan; Catherine Ewen; R Chris Bleackley; Bhagirath Singh
A novel mechanism of regulatory T cell-mediated down-regulation of autoimmunity.
International immunology 2006;18(7):1001-15.
2005: Rinee Mukherjee; Danielle Wagar; Tracey A Stephens; Edwin Lee-Chan; Bhagirath Singh
Identification of CD4+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: a novel beta cell autoantigen in type 1 diabetes.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5306-15.
2005: Matilde Leon-Ponte; Mark G Kirchhof; Tina Sun; Tracey Stephens; Bhagirath Singh; Shabaz Sandhu; Joaquín Madrenas
Polycationic lipids inhibit the pro-inflammatory response to LPS.
Immunology letters 2005;96(1):73-83.
2004: Ashish Rajput; Bhagirath Singh
Gene expression profiling in type 1 diabetes prone NOD mice immunized with a disease protective autoantigenic peptide.
Journal of autoimmunity 2004;23(4):311-21.
2004: Clara Bueno; Kenneth K Lee; Luan A Chau; Edwin Lee-Chan; Bhagirath Singh; Gill H Strejan; Joaquín Madrenas
Mechanism of modulation of T cell responses by N-palmitoylated peptides.
European journal of immunology 2004;34(12):3497-507.
2004: Hui-Yu Qin; Pratibha Chaturvedi; Bhagirath Singh
In vivo apoptosis of diabetogenic T cells in NOD mice by IFN-gamma/TNF-alpha.
International immunology 2004;16(12):1723-32.
2004: Holly Y Young; Peter Zucker; Richard A Flavell; Anthony M Jevnikar; Bhagirath Singh
Characterization of the role of major histocompatibility complex in type 1 diabetes recurrence after islet transplantation.
Transplantation 2004;78(4):509-15.
2004: Bhagirath Singh
Innovation and challenges in funding rapid research responses to emerging infectious diseases: Lessons learned from the outbreak of severe acute respiratory syndrome.
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie médicale / AMMI Canada 2004;15(3):167-70.
2003: Rinee Mukherjee; Pratibha Chaturvedi; Hui-Yu Qin; Bhagirath Singh
CD4+CD25+ regulatory T cells generated in response to insulin B:9-23 peptide prevent adoptive transfer of diabetes by diabetogenic T cells.
Journal of autoimmunity 2003;21(3):221-37.
2003: Hui-Yu Qin; Jeffrey L Mahon; Mark A Atkinson; Pratibha Chaturvedi; Edwin Lee-Chan; Bhagirath Singh
Type 1 diabetes alters anti-hsp90 autoantibody isotype.
Journal of autoimmunity 2003;20(3):237-45.
2002: Annette M Marleau; Bhagirath Singh
Myeloid dendritic cells in non-obese diabetic mice have elevated costimulatory and T helper-1-inducing abilities.
Journal of autoimmunity 2002;19(1-2):23-35.
2002: Anthony M Jevnikar; Sean Prange; Peter Zucker; Bhagirath Singh
Role of donor MHC class III genes in the destruction of transplanted islets in NOD mice.
Annals of the New York Academy of Sciences 2002;958():175-8.
2002: Ezio Bonifacio; Mark Atkinson; George S Eisenbarth; David V Serreze; Thomas W H Kay; Edwin Lee-Chan; Bhagirath Singh
International Workshop on Lessons from Animal Models for Human Type 1 Diabetes: analyzing target autoantigens of humoral immunity in nonobese diabetic mice.
Annals of the New York Academy of Sciences 2002;958():1-2.
2001: Ezio Bonifacio; M Atkinson; George S Eisenbarth; David V Serreze; T W Kay; Edwin Lee-Chan; Bhagirath Singh
International Workshop on Lessons From Animal Models for Human Type 1 Diabetes: identification of insulin but not glutamic acid decarboxylase or IA-2 as specific autoantigens of humoral autoimmunity in nonobese diabetic mice.
Diabetes 2001;50(11):2451-8.
2001: Sean Prange; Peter Zucker; Anthony M Jevnikar; Bhagirath Singh
Transplanted MHC class I-deficient nonobese diabetic mouse islets are protected from autoimmune injury in diabetic nonobese recipients.
Transplantation 2001;71(7):982-5.
2001: J St Louis; Shashi Uniyal; Luoling Xu; E Chan; Bhagirath Singh; Bosco M C Chan; Gill H Strejan
Tolerance induction by acylated peptides: suppression of EAE in the mouse with palmitoylated PLP peptides.
Journal of neuroimmunology 2001;115(1-2):79-90.
2000: Bhagirath Singh; Terry L Delovitch
Immune mechanisms that regulate susceptibility to autoimmune type I diabetes.
Clinical reviews in allergy & immunology 2000;19(3):247-64.
2000: Yen-Tung A Teng; H Nguyen; X Gao; Y Y Kong; RM Gorczynski; Bhagirath Singh; R P Ellen; Josef M Penninger
Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection.
The Journal of clinical investigation 2000;106(6):R59-67.
2000: Pratibha Chaturvedi; B Agrawal; MA Zechel; Edwin Lee-Chan; Bhagirath Singh
A self MHC class II beta-chain peptide prevents diabetes in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(12):6610-20.
2000: Pratibha Chaturvedi; R Hengeveld; MA Zechel; Edwin Lee-Chan; Bhagirath Singh
The functional role of class II-associated invariant chain peptide (CLIP) in its ability to variably modulate immune responses.
International immunology 2000;12(6):757-65.
2000: Benoît L Salomon; D J Lenschow; L Rhee; N Ashourian; Bhagirath Singh; A Sharpe; Jeffrey A Bluestone
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes.
Immunity 2000;12(4):431-40.
2000: Bhagirath Singh
Stimulation of the developing immune system can prevent autoimmunity.
Journal of autoimmunity 2000;14(1):15-22.
1999: J St Louis; X M Zhang; E Heber-Katz; Shashi Uniyal; D Robbinson; Bhagirath Singh; Gill H Strejan
Tolerance induction by acylated peptides: effect on encephalitogenic T cell lines.
Journal of autoimmunity 1999;12(3):177-89.
1999: Shashi Uniyal; L Boeters; Subrata Chakrabarti; Bhagirath Singh; Bosco M C Chan
Leukocytes utilize both alpha4 and alpha5 integrins for intraislet infiltration in non-obese diabetic mice.
Journal of autoimmunity 1999;12(3):167-76.
1999: Andrew Lazarovits; Lydia Visser; S Asfar; C E LeFeuvre-Haddad; T Zhong; David J Kelvin; C Kong; MH Khandaker; Bhagirath Singh; M White; A M Jevnikar; Z Zhang; Sibrand Poppema
Mechanisms of induction of renal allograft tolerance in CD45RB-treated mice.
Kidney international 1999;55(4):1303-10.
1999: R Rahimpour; G Mitchell; MH Khandaker; C Kong; Bhagirath Singh; Luoling Xu; Atsuo Ochi; Ross D Feldman; J Geoffrey Pickering; BM Gill; David J Kelvin
Bacterial superantigens induce down-modulation of CC chemokine responsiveness in human monocytes via an alternative chemokine ligand-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(4):2299-307.
1998: Hui-Yu Qin; John Elliott; J R Lakey; R V Rajotte; Bhagirath Singh
Endogenous immune response to glutamic acid decarboxylase (GAD67) in NOD mice is modulated by adjuvant immunotherapy.
Journal of autoimmunity 1998;11(6):591-601.
1998: MA Zechel; M D Krawetz; Bhagirath Singh
Epitope dominance: evidence for reciprocal determinant spreading to glutamic acid decarboxylase in non-obese diabetic mice.
Immunological reviews 1998;164():111-8.
1998: C Kong; BM Gill; R Rahimpour; Luoling Xu; Ross D Feldman; Q Xiao; T J McDonald; LAURENT TAUPENOT; Sushil K Mahata; Bhagirath Singh; Daniel O'Connor; David J Kelvin
Secretoneurin and chemoattractant receptor interactions.
Journal of neuroimmunology 1998;88(1-2):91-8.
1998: Bhagirath Singh; Sean Prange; Anthony M Jevnikar
Protective and destructive effects of microbial infection in insulin-dependent diabetes mellitus.
Seminars in immunology 1998;10(1):79-86.
1998: MA Zechel; John Elliott; M A Atkinson; Bhagirath Singh
Characterization of novel T-cell epitopes on 65 kDa and 67 kDa glutamic acid decarboxylase relevant in autoimmune responses in NOD mice.
Journal of autoimmunity 1998;11(1):83-95.
1998: A Nabavieh; H Chou; I Volokhov; J E Lee; L E Purdy; John Elliott; Bhagirath Singh; J Madrenas
Development of an I-Ag7-expressing antigen-presenting cell line: intrinsic molecular defect in compact I-Ag7 dimer generation.
Journal of autoimmunity 1998;11(1):63-71.
1997: Bhagirath Singh; J F Elliot
Can progression of IDDM be prevented in newly diagnosed patients by BCG immunotherapy?
Diabetes/metabolism reviews 1997;13(4):320-1.
1997: Terry L Delovitch; Bhagirath Singh
The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.
Immunity 1997;7(6):727-38.
1997: Guillermo A Arreaza; Mark Cameron; A Jaramillo; B M Gill; D Hardy; K B Laupland; M J Rapoport; Peter Zucker; Subrata Chakrabarti; Stephen W Chensue; H Y Qin; Bhagirath Singh; Terry L Delovitch
Neonatal activation of CD28 signaling overcomes T cell anergy and prevents autoimmune diabetes by an IL-4-dependent mechanism.
The Journal of clinical investigation 1997;100(9):2243-53.
1997: S W Ma; D L Zhao; Z Q Yin; Rinee Mukherjee; Bhagirath Singh; Hui-Yu Qin; C R Stiller; Anthony M Jevnikar
Transgenic plants expressing autoantigens fed to mice to induce oral immune tolerance.
Nature medicine 1997;3(7):793-6.
1997: J E Lee; M B Cossoy; Luan A Chau; Bhagirath Singh; Joaquín Madrenas
Inactivation of lck and loss of TCR-mediated signaling upon persistent engagement with complexes of peptide:MHC molecules.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):61-9.
1997: MA Zechel; Pratibha Chaturvedi; Bhagirath Singh
Characterization of immunodominant peptide determinants of IDDM-associated autoantigens in the NOD mouse.
Research in immunology 1997;148(5):338-48.
1997: Hui-Yu Qin; Bhagirath Singh
BCG vaccination prevents insulin-dependent diabetes mellitus (IDDM) in NOD mice after disease acceleration with cyclophosphamide.
Journal of autoimmunity 1997;10(3):271-8.
1997: J St Louis; E L Chan; Bhagirath Singh; Gill H Strejan
Suppression of experimental allergic encephalomyelitis in the Lewis rat, by administration of an acylated synthetic peptide of myelin basic protein.
Journal of neuroimmunology 1997;73(1-2):90-100.
1997: B D Reid; Hui-Yu Qin; Sean Prange; Edwin Lee-Chan; Q Yu; John Elliott; Bhagirath Singh
Modulation and detection of IDDM by membrane associated antigens from the islet beta cell line NIT-1.
Journal of autoimmunity 1997;10(1):27-34.
1997: Pratibha Chaturvedi; Hui-Yu Qin; H Chou; Bhagirath Singh
Modulation of insulin-dependent diabetes mellitus (IDDM) in NOD mice by autoreactive T cells.
Critical reviews in immunology 1997;17(5-6):519-28.
1996: D J Lenschow; KC Herold; L Rhee; B Patel; A Koons; H Y Qin; E Fuchs; Bhagirath Singh; Craig Thompson; Jeffrey A Bluestone
CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes.
Immunity 1996;5(3):285-93.
1996: M S Hanson; Marina Cetkovic-Cvrlje; V K Ramiya; M A Atkinson; N K Maclaren; Bhagirath Singh; John Elliott; David V Serreze; Edward H Leiter
Quantitative thresholds of MHC class II I-E expressed on hemopoietically derived antigen-presenting cells in transgenic NOD/Lt mice determine level of diabetes resistance and indicate mechanism of protection.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(3):1279-87.
1996: MA Zechel; P Chaturvedi; E C Lee-Chan; Beverley Rider; Bhagirath Singh
Modulation of antigen presentation and class II expression by a class II-associated invariant chain peptide.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(11):4232-9.
1996: Beverley Rider; E Fraga; Q Yu; Bhagirath Singh
Immune responses to self peptides naturally presented by murine class II major histocompatibility complex molecules.
Molecular immunology 1996;33(7-8):625-33.
1996: P Chaturvedi; Q Yu; Scott Southwood; A Sette; Bhagirath Singh
Peptide analogs with different affinites for MHC alter the cytokine profile of T helper cells.
International immunology 1996;8(5):745-55.
1996: Christoph Ballestrem; Shashi Uniyal; J I McCormick; T Chau; Bhagirath Singh; Bosco M C Chan
VLA-beta 1 integrin subunit-specific monoclonal antibodies MB1.1 and MB1.2: binding to epitopes not dependent on thymocyte development or regulated by phorbol ester and divalent cations.
Hybridoma 1996;15(2):125-32.
1996: D Robbinson; S Cockle; Bhagirath Singh; Gill H Strejan
Native, but not genetically inactivated, pertussis toxin protects mice against experimental allergic encephalomyelitis.
Cellular immunology 1996;168(2):165-73.
1995: R Mantle; Bhagirath Singh; vladimir hachinski
Do serum antibodies to heat-shock protein 65 relate to age or stroke?
Lancet 1995;346(8991-8992):1715.
1995: Jonathan R T Lakey; Bhagirath Singh; Garth L Warnock; John Elliott; Ray V Rajotte
Dose dependence of bacillus Calmette-Guerin on the prevention of autoimmune diabetes in syngeneic islet transplantation.
Transplantation proceedings 1995;27(6):3413.
1995: Jonathan R T Lakey; Bhagirath Singh; Garth L Warnock; John Elliott; Ray V Rajotte
Long-term survival of syngeneic islet grafts in BCG-treated diabetic NOD mice can be reversed by cyclophosphamide.
Transplantation 1995;59(12):1751-3.
1994: John Elliott; H Y Qin; S Bhatti; D K Smith; R K Singh; T Dillon; J Lauzon; Bhagirath Singh
Immunization with the larger isoform of mouse glutamic acid decarboxylase (GAD67) prevents autoimmune diabetes in NOD mice.
Diabetes 1994;43(12):1494-9.
1994: T T Duong; Fred D Finkelman; Bhagirath Singh; Gill H Strejan
Effect of anti-interferon-gamma monoclonal antibody treatment on the development of experimental allergic encephalomyelitis in resistant mouse strains.
Journal of neuroimmunology 1994;53(1):101-7.
1994: J M St Louis; J M Pasick; C Stein; D Freeman; Bhagirath Singh; S Dales; Gill H Strejan
Lewis rat T cells can reutilize, process, and present myelin basic protein to antigen-specific T cell lines.
Cellular immunology 1994;156(1):36-53.
1994: Jonathan R T Lakey; Bhagirath Singh; Garth L Warnock; Ray V Rajotte
BCG immunotherapy prevents recurrence of diabetes in islet grafts transplanted into spontaneously diabetic NOD mice.
Transplantation 1994;57(8):1213-7.
1994: Jonathan R T Lakey; Garth L Warnock; Bhagirath Singh; Ray V Rajotte
Adjuvant immunotherapy with Bacillus Calmette-Guerin prevents recurrence of diabetes in islet grafts transplanted into NOD mice.
Transplantation proceedings 1994;26(2):736.
1994: Bhagirath Singh; T Dillion; J Lauzon; E Fraga; Anthony S Russell
Tolerance to the HLA-B27 and Klebsiella pneumoniae crossreactive epitope in mice transgenic for HLA-B2705 and human beta 2-microglobulin.
The Journal of rheumatology 1994;21(4):670-4.
1994: Babita Agrawal; E Fraga; K Kane; Bhagirath Singh
Up-regulation of the MHC class II molecules on B cells by peptide ligands.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(3):965-75.
1993: D MacNeil; E Fraga; Bhagirath Singh
Characterization of murine T cell responses to peptides of the variable region of self T cell receptor beta-chains.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(8):4045-54.
1993: W Smart; P A Sastry; W Paranchych; Bhagirath Singh
Immune recognition of polar pili from Pseudomonas aeruginosa O.
Infection and immunity 1993;61(8):3527-9.
1993: H Y Qin; Michel Sadelain; C Hitchon; J Lauzon; Bhagirath Singh
Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer of diabetes in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(5):2072-80.
1993: Bhagirath Singh; Alex Rabinovitch
Influence of microbial agents on the development and prevention of autoimmune diabetes.
Autoimmunity 1993;15(3):209-13.
1992: Jonathan R T Lakey; T Wang; Garth L Warnock; Bhagirath Singh; Ray V Rajotte
Prevention of recurrence of insulin-dependent diabetes mellitus in islet cell-transplanted diabetic NOD mice using adjuvant therapy.
Transplantation proceedings 1992;24(6):2848.
1992: Z Novak; E Fraga; Bhagirath Singh
Evidence for immunodominance between closely related epitopes in the selection of T cell repertoire: hierarchy of T cell epitopes in a repeating sequence.
Molecular immunology 1992;29(12):1467-76.
1992: D K Smith; T Kassam; Bhagirath Singh; John Elliott
Escherichia coli has two homologous glutamate decarboxylase genes that map to distinct loci.
Journal of bacteriology 1992;174(18):5820-6.
1992: D MacNeil; E Fraga; Bhagirath Singh
Inhibition of superantigen recognition by peptides of the variable region of the T cell receptor beta chain.
European journal of immunology 1992;22(4):937-41.
1992: Z Novak; M Boyer; P Kilgannon; E Fraga; Arun Fotedar; Bhagirath Singh
Unusually diverse T cell response to a repeating tripeptide epitope.
Cellular immunology 1992;140(1):206-18.
1992: T Wang; Bhagirath Singh; Garth L Warnock; Ray V Rajotte
Prevention of recurrence of IDDM in islet-transplanted diabetic NOD mice by adjuvant immunotherapy.
Diabetes 1992;41(1):114-7.
1991: Babita Agrawal; M Manickasundari; E Fraga; Bhagirath Singh
T cells that recognize peptide sequences of self MHC class II molecules exist in syngeneic mice.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(2):383-90.
1991: J T Venkatraman; Daniel J Pehowich; Bhagirath Singh; Ray V Rajotte; Alan B R Thomson; M Thomas Clandinin
Effect of dietary fat on diabetes-induced changes in liver microsomal fatty acid composition and glucose-6-phosphatase activity in rats.
Lipids 1991;26(6):441-4.
1991: Reid P Bissonnette; H G Zheng; R T Kubo; Bhagirath Singh; Douglas R Green
A T helper cell hybridoma produces an antigen-specific regulatory activity. Relationship to the T cell receptor by serology and antigenic fine specificity.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(9):2898-907.
1991: JF Krowka; Bhagirath Singh; Daniel P Stites; V C Maino; D Narindray; H Hollander; S Jain; H Chen; L Blackwood; K S Steimer
Epitopes of human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins recognized by antibodies in the sera of HIV-1-infected individuals.
Clinical immunology and immunopathology 1991;59(1):53-64.
1990: Michel Sadelain; H Y Qin; W Sumoski; Nollaig A Parfrey; Bhagirath Singh; Alex Rabinovitch
Prevention of diabetes in the BB rat by early immunotherapy using Freund's adjuvant.
Journal of autoimmunity 1990;3(6):671-80.
1990: Kohtaro Fujihashi; T Taguchi; Jerry R McGhee; John H Eldridge; M G Bruce; D R Green; Bhagirath Singh; Hiroshi Kiyono
Regulatory function for murine intraepithelial lymphocytes. Two subsets of CD3+, T cell receptor-1+ intraepithelial lymphocyte T cells abrogate oral tolerance.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(7):2010-9.
1990: Bhagirath Singh; T Dillon; E Fraga; J Lauzon
Role of the first external domain of I-A beta chain in immune responses and diabetes in non-obese diabetic (NOD) mice.
Journal of autoimmunity 1990;3(5):507-21.
1990: M Boyer; Z Novak; Arun Fotedar; E Fraga; Bhagirath Singh
Critical role of an amino acid residue in a T cell determinant is due to its interaction with a neighboring non-critical residue.
European journal of immunology 1990;20(9):2145-8.
1990: Arun Fotedar; W Smart; M Boyer; T Dillon; E Fraga; J Lauzon; E M Shevach; Bhagirath Singh
Characterization of agretopes and epitopes involved in the presentation of beef insulin to T cells.
Molecular immunology 1990;27(7):603-11.
1990: Michel Sadelain; H Y Qin; J Lauzon; Bhagirath Singh
Prevention of type I diabetes in NOD mice by adjuvant immunotherapy.
Diabetes 1990;39(5):583-9.
1990: Y F Shi; M G Szalay; L Paskar; B M Sahai; M Boyer; Bhagirath Singh; Douglas R Green
Activation-induced cell death in T cell hybridomas is due to apoptosis. Morphologic aspects and DNA fragmentation.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3326-33.
1990: S Fraga; E San-Fabian; S Thornton; Bhagirath Singh
Prediction of the secondary structure and functional sites of major histocompatibility complex molecules.
Journal of molecular recognition : JMR 1990;3(2):65-73.
1990: M Boyer; Z Novak; E Fraga; K Oikawa; C M Kay; Arun Fotedar; Bhagirath Singh
Functional degeneracy of residues in a T cell peptide epitope contributes to its recognition by different T cell hybridomas.
International immunology 1990;2(12):1221-33.
1989: Kohtaro Fujihashi; Hiroshi Kiyono; Wilhelm K Aicher; D R Green; Bhagirath Singh; John H Eldridge; Jerry R McGhee
Immunoregulatory function of CD3+, CD4-, and CD8- T cells. Gamma delta T cell receptor-positive T cells from nude mice abrogate oral tolerance.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(11):3415-22.
1989: Bhagirath Singh; K C Lee; E Fraga
Hydrophobic amino acid residues in peptide antigens determine the genetic control of immune responses.
Peptide research 1989;2(1):120-7.
1988: Bhagirath Singh; J Lauzon; J Venkatraman; Alan B R Thomson; Ray V Rajotte; M Thomas Clandinin
Effect of high/low dietary linoleic acid levels on the function and fatty acid composition of T-lymphocytes of normal and diabetic rats.
Diabetes research (Edinburgh, Scotland) 1988;8(3):129-34.
1988: P Naquet; J Ellis; D Tibensky; A Kenshole; Bhagirath Singh; R Hodges; Terry L Delovitch
T cell autoreactivity to insulin in diabetic and related non-diabetic individuals.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(8):2569-78.
1988: M Boyer; Z Novak; Arun Fotedar; Bhagirath Singh
Contribution of antigen processing to the recognition of a synthetic peptide antigen by specific T cell hybridomas.
Journal of molecular recognition : JMR 1988;1(2):99-106.
1988: H Zheng; M Boyer; Arun Fotedar; Bhagirath Singh; Douglas R Green
An antigen-specific helper T cell hybridoma produces an antigen-specific suppressor inducer molecule with identical antigenic fine specificity. Implications for the antigen recognition and function of helper and suppressor inducer T cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(5):1351-8.
1988: Ray V Rajotte; C L Erickson; M Thomas Clandinin; Alan B R Thomson; Bhagirath Singh
Clinical response to feeding a high polyunsaturated fat diet in normal and diabetic rats.
Diabetes research (Edinburgh, Scotland) 1988;7(1):41-7.
1988: W Smart; P A Sastry; W Paranchych; Bhagirath Singh
Mapping of the T-cell recognition sites of Pseudomonas aeruginosa PAK polar pili.
Infection and immunity 1988;56(1):18-23.
1987: P Naquet; J Ellis; Bhagirath Singh; R S Hodges; Terry L Delovitch
Processing and presentation of insulin. I. Analysis of immunogenic peptides and processing requirements for insulin A loop-specific T cells.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(12):3955-63.
1987: M L Langsford; Neil Gilkes; Bhagirath Singh; Bernhard Moser; R C Miller; R Antony J Warren; Douglas G Kilburn
Glycosylation of bacterial cellulases prevents proteolytic cleavage between functional domains.
FEBS letters 1987;225(1-2):163-7.
1987: B S Fox; C Chen; E Fraga; C A French; Bhagirath Singh; R H Schwartz
Functionally distinct agretopic and epitopic sites. Analysis of the dominant T cell determinant of moth and pigeon cytochromes c with the use of synthetic peptide antigens.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(5):1578-88.
1986: Bhagirath Singh; C A Waters; D Swanlund
Alloantigenic sites on class I major histocompatibility complex antigens: 61-69 region in the first domain of the H-2Kb molecule induces specific antibody and T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(7):2311-8.
1986: J F Krowka; Bhagirath Singh; A Fotedar; TR Mosmann; M A Giedlin; Linda M Pilarski
A requirement for physical linkage between determinants recognized by helper molecules and cytotoxic T cell precursors in the induction of cytotoxic T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(10):3561-6.
1986: P D Kilgannon; E Fraga; Bhagirath Singh
Fine-specificity analysis of antibodies directed to the C-terminal peptides of cytochrome c recognized by T-lymphocytes.
Molecular immunology 1986;23(3):311-8.
1986: R Singh; Bhagirath Singh; S K Malhotra
A new "marker" protein for astrocytes.
Bioscience reports 1986;6(1):73-80.
1985: T Morinaga; A Fotedar; Bhagirath Singh; T G Wegmann; T Tamaoki
Isolation of cDNA clones encoding a T-cell receptor beta-chain from a beef insulin-specific hybridoma.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(23):8163-7.
1985: Arun Fotedar; M Boyer; W Smart; J Widtman; E Fraga; Bhagirath Singh
Fine specificity of antigen recognition by T cell hybridoma clones specific for poly-18: a synthetic polypeptide antigen of defined sequence and conformation.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(5):3028-33.
1985: R H Schwartz; B S Fox; E Fraga; C Chen; Bhagirath Singh
The T lymphocyte response to cytochrome c. V. Determination of the minimal peptide size required for stimulation of T cell clones and assessment of the contribution of each residue beyond this size to antigenic potency.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(4):2598-608.
1985: S Fraga; Bhagirath Singh
Theoretical prediction of the determinants of transplantation antigens.
Progress in clinical and biological research 1985;172B():379-88.
1984: M J Poznansky; R Singh; Bhagirath Singh; G Fantus
Insulin: carrier potential for enzyme and drug therapy.
Science (New York, N.Y.) 1984;223(4642):1304-6.
1984: Raj Raghupathy; Bhagirath Singh; T G Wegmann
Fate of antipaternal H-2 antibodies bound to the placenta in vivo.
Transplantation 1984;37(3):296-300.
1984: R Liu; F Pazderka; Bhagirath Singh; J B Dossetor
Detection of IgG in supernatants of pokeweed mitogen-stimulated human lymphocyte cultures by one step solid-phase radioimmunoassay (SPRIA).
Immunological communications 1984;13(2):105-18.
1984: M Jakobisiak; Bhagirath Singh; S Saidman; J Schlaut; J B Dossetor
Anti-IgM antibodies may regulate the humoral response to paternal HLA antigens in pregnant women.
Clinical and investigative medicine. Médecine clinique et experimentale 1984;7(2):123-5.
1983: E A Worobec; P Shastry; W Smart; R Bradley; Bhagirath Singh; W Paranchych
Monoclonal antibodies against colonization factor antigen I pili from enterotoxigenic Escherichia coli.
Infection and immunity 1983;41(3):1296-301.
1982: Bhagirath Singh; Raj Raghupathy; A R Shaw; D G Tews; M S Hamilton; T G Wegmann
Characterization and cross-reactivity of human and mouse oncofetal antigens. Use of a new solid phase assay for detection of cell surface antigens.
Transplantation 1982;33(2):156-62.
1981: E Nisbet-Brown; Bhagirath Singh; E Diener
Antigen recognition. V. Requirement for histocompatibility between antigen-presenting cell and B cell in the response to a thymus-dependent antigen, and lack of allogeneic restriction between T and B cells.
The Journal of experimental medicine 1981;154(3):676-87.
1980: Bhagirath Singh; K C Lee; E Fraga; A Wilkinson; M Wong; M A Barton
Minimum peptide sequences necessary for priming and triggering of humoral and cell-mediated immune responses in mice: use of synthetic peptide antigens of defined structure.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(3):1336-43.
1979: T G Wegmann; T R Mosmann; G A Carlson; O Olijnyk; Bhagirath Singh
The ability of the murine placenta to absorb monoclonal anti-fetal H-2K antibody from the maternal circulation.
Journal of immunology (Baltimore, Md. : 1950) 1979;123(3):1020-3.
1979: T G Wegmann; Bhagirath Singh; G A Carlson
Allogeneic placenta is a paternal strain antigen immunoabsorbent.
Journal of immunology (Baltimore, Md. : 1950) 1979;122(1):270-4.
1979: K C Lee; Bhagirath Singh; M A Barton; A Procyshyn; M Wong
A simple reliable system for studying antigen-specific murine T cell proliferation.
Journal of immunological methods 1979;25(2):159-70.
1978: Bhagirath Singh; E Fraga; M A Barton
Characterization and genetic control of the immune response to synthetic polypeptide antigens of defined geometry.
Journal of immunology (Baltimore, Md. : 1950) 1978;121(2):784-9.
1977: M A Barton; Bhagirath Singh; E Fraga
Synthetic polypeptide antigens of defined geometry.
Journal of the American Chemical Society 1977;99(26):8491-8.
1977: C Shiozawa; Bhagirath Singh; S Rubinstein; E Diener
Molecular control of B cell triggering by antigen-specific T cell-derived helper factor.
Journal of immunology (Baltimore, Md. : 1950) 1977;118(6):2199-205.
1977: E Diener; C Shiozawa; Bhagirath Singh; K C Lee
Cellular and molecular interactions in control of B-cell immunity and tolerance.
Cold Spring Harbor symposia on quantitative biology 1977;41 Pt 1():251-9.