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Knut Wittkowski

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Knut M Wittkowski; Mehdi Keddache; Martin P Seybold; Vikas Sonakya; Tingting Song; Martina Durner
From single-SNP to wide-locus: genome-wide association studies identifying functionally related genes and intragenic regions in small sample studies.
Ida Sim; Samson W Tu; Knut M Wittkowski; James Brinkley; Karl Burke; Simona Carini; Swati Chakraborty; Landon T Detwiler; Vojtech Huser; Thomas M Johnson; Harold Lehmann; Shamim A Mollah; Brad H Pollock
Ontology-based federated data access to human studies information.
Doris McGartland Rubio; Leah J Welty; Knut M Wittkowski; Rafia Bhore; Deborah J Del Junco; Dave Demets; Yi-Ju Li; Christopher J Lindsell; Robert A Oster
Evaluation metrics for biostatistical and epidemiological collaborations.

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All Publications

2013: Knut M Wittkowski; Mehdi Keddache; Martin P Seybold; Vikas Sonakya; Tingting Song; Martina Durner
From single-SNP to wide-locus: genome-wide association studies identifying functionally related genes and intragenic regions in small sample studies.
Pharmacogenomics 2013;14(4):391-401.
2012: Ida Sim; Samson W Tu; Knut M Wittkowski; James Brinkley; Karl Burke; Simona Carini; Swati Chakraborty; Landon T Detwiler; Vojtech Huser; Thomas M Johnson; Harold Lehmann; Shamim A Mollah; Brad H Pollock
Ontology-based federated data access to human studies information.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2012;2012():856-65.
2011: Doris McGartland Rubio; Leah J Welty; Knut M Wittkowski; Rafia Bhore; Deborah J Del Junco; Dave Demets; Yi-Ju Li; Christopher J Lindsell; Robert A Oster
Evaluation metrics for biostatistical and epidemiological collaborations.
Statistics in medicine 2011;30(23):2767-77.
2011: Knut M Wittkowski; Jennifer Belasco; Alice Gottlieb; John Gray; Liz Horn; Gerald G Krueger; James G Krueger; Craig Leonardi; Alan Menter; Razieh Soltani-Arabshahi; Paul W Tebbey
Clinical symptoms of skin, nails, and joints manifest independently in patients with concomitant psoriasis and psoriatic arthritis.
PloS one 2011;6(6):e20279.
2011: Te Piao King; Knut M Wittkowski
Hyaluronidase and hyaluronan in insect venom allergy.
International archives of allergy and immunology 2011;156(2):205-11.
2009: Knut M Wittkowski
"Assessment of Multiple Ordinal Endpoints" by L. Häberle, A. Pfahlberg and O. Gefeller: biometrical journal (2009) 51, 217-226 article.
Biometrical journal. Biometrische Zeitschrift 2009;51(5):870-1; author reply 872-3.
2009: Monesha Gupta-Malhotra; Dorota Gruber; Seena S Abraham; Mary J Roman; John B Zabriskie; Lisa C Hudgins; Patrick A Flynn; Daniel M Levine; Uzoma Okorie; Aline Baday; Myles S. Schiller; Janet Maturi; Diane Meehan; Joshua Dyme; Thomas S Parker; Knut M Wittkowski; Welton M Gersony; Rubin S Cooper
Atherosclerosis in survivors of Kawasaki disease.
The Journal of pediatrics 2009;155(4):572-7.
2009: Jasimuddin Ahamed; Christin A Janczak; Knut M Wittkowski; Barry S Coller
In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1.
PloS one 2009;4(8):e6608.
2009: Sreeram V Ramagopalan; Roisin McMahon; David A Dyment; A Dessa Sadovnick; George C Ebers; Knut M Wittkowski
An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1 gene.
BMC medical genetics 2009;10():10.
2008: Damien Chaussabel; Charlie Quinn; Jing Shen; Pinakeen Patel; Casey Glaser; Nicole Baldwin; Dorothee Stichweh; Derek Blankenship; Lei Li; Indira Munagala; Lynda Bennett; Florence Allantaz; Asuncion Mejias; Monica Ardura; Ellen Kaizer; Laurence Monnet; Windy Allman; Henry Randall; Diane Johnson; Aimee Lanier; Marilynn Punaro; Knut M Wittkowski; Perrin White; Joseph Fay; Goran Klintmalm; Octavio Ramilo; A Karolina Palucka; Jacques Banchereau; Virginia Pascual
A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus.
Immunity 2008;29(1):150-64.
2008: Kim A Papp; Philippe Fonjallaz; Florence Casset-Semanaz; James G Krueger; Knut M Wittkowski
Analytical approaches to reporting long-term clinical trial data.
Current medical research and opinion 2008;24(7):2001-8.
2008: Asifa S Haider; Michelle A Lowes; Mayte Suárez-Fariñas; Lisa C Zaba; Irma Cardinale; Artemis Khatcherian; Inna Novitskaya; Knut M Wittkowski; James G Krueger
Identification of cellular pathways of "type 1," Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1913-20.
2008: José F Morales; Tingting Song; Arleen D Auerbach; Knut M Wittkowski
Phenotyping genetic diseases using an extension of mu-scores for multivariate data.
Statistical applications in genetics and molecular biology 2008;7(1):Article 19.
2008: Eric Scott Sills; T M Kling; S S Sills; M J Burns; L P Carroll; L D Parker; Knut M Wittkowski
Women's health measures in two North Carolina regions sampled from the Basic Automated Birth Yearbook (BABY) datasets: experimental findings, methodological limits and future directions.
Clinical and experimental obstetrics & gynecology 2008;35(1):27-31.
2007: Emilio Quaia; Mirko D'Onofrio; paolo cabassa; Francesca Vecchiato; Sabrina Caffarri; Frida Pittiani; Knut M Wittkowski; Maria Cova
Diagnostic value of hepatocellular nodule vascularity after microbubble injection for characterizing malignancy in patients with cirrhosis.
AJR. American journal of roentgenology 2007;189(6):1474-83.
2007: Deborah N Shelley; Evarose Dwyer; Carolyn Johnson; Knut M Wittkowski; Donald Pfaff
Interactions between estrogen effects and hunger effects in ovariectomized female mice. I. Measures of arousal.
Hormones and behavior 2007;52(4):546-53.
2007: Octavio Ramilo; Windy Allman; Wendy Chung; Asuncion Mejias; Monica Ardura; Casey Glaser; Knut M Wittkowski; Bernard Piqueras; Jacques Banchereau; A Karolina Palucka; Damien Chaussabel
Gene expression patterns in blood leukocytes discriminate patients with acute infections.
Blood 2007;109(5):2066-77.
2007: Francesca Chamian; Shao-Lee Lin; Edmund Lee; Toyoko Kikuchi; Patricia Gilleaudeau; Mary Sullivan-Whalen; Irma Cardinale; Artemis Khatcherian; Inna Novitskaya; Knut M Wittkowski; James G Krueger; Michelle A Lowes
Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis.
Journal of translational medicine 2007;5():27.
2006: Maurizio Pellegrino; Mayte Suárez-Fariñas; Marcelo O Magnasco; Knut M Wittkowski
Detecting artifacts on SNP chips.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2006;1():4100-2.
2006: Knut M Wittkowski; Asifa S Haider; Ephraim Sehayek; Mayte Suárez-Fariñas; Maurizio Pellegrino; Alexandre Peshansky; Cameron Coffran; Sanford Coker
Bioinformatics tools enabling u-statistics for microarrays.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2006;1():3464-9.
2005: Michelle A Lowes; Francesca Chamian; Maria Veronica Abello; Judilyn Fuentes-Duculan; Shao-Lee Lin; RACHEL NUSSBAUM; Inna Novitskaya; Henrietta Carbonaro; Irma Cardinale; Toyoko Kikuchi; Patricia Gilleaudeau; Mary Sullivan-Whalen; Knut M Wittkowski; Kim A Papp; Marvin Garovoy; Wolfgang Dummer; Ralph M Steinman; James G Krueger
Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a).
Proceedings of the National Academy of Sciences of the United States of America 2005;102(52):19057-62.
2005: Francesca Chamian; Michelle A Lowes; Shao-Lee Lin; Edmund Lee; Toyoko Kikuchi; Patricia Gilleaudeau; Mary Sullivan-Whalen; Irma Cardinale; Artemis Khatcherian; Inna Novitskaya; Knut M Wittkowski; James G Krueger
Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2075-80.
2005: Mayte Suárez-Fariñas; Maurizio Pellegrino; Knut M Wittkowski; Marcelo O Magnasco
Harshlight: a "corrective make-up" program for microarray chips.
BMC bioinformatics 2005;6():294.
2005: Mayte Suárez-Fariñas; Asifa S Haider; Knut M Wittkowski
"Harshlighting" small blemishes on microarrays.
BMC bioinformatics 2005;6():65.
2004: Knut M Wittkowski
Effects and non-effects of paired identical observations in comparing proportions with binary matched-pairs data.
Statistics in medicine 2004;23(14):2317.
2004: Sophie Paczesny; Jacques Banchereau; Knut M Wittkowski; Giovanna Saracino; Joseph Fay; A Karolina Palucka
Expansion of melanoma-specific cytolytic CD8+ T cell precursors in patients with metastatic melanoma vaccinated with CD34+ progenitor-derived dendritic cells.
The Journal of experimental medicine 2004;199(11):1503-11.
2004: Knut M Wittkowski; Edmund Lee; RACHEL NUSSBAUM; Francesca Chamian; James G Krueger
Combining several ordinal measures in clinical studies.
Statistics in medicine 2004;23(10):1579-92.
2004: Rudolph Spangler; Knut M Wittkowski; Noel L Goddard; Nicole M Avena; Bartley G Hoebel; Sarah F Leibowitz
Opiate-like effects of sugar on gene expression in reward areas of the rat brain.
Brain research. Molecular brain research 2004;124(2):134-42.
2003: A Karolina Palucka; Madhav V Dhodapkar; Sophie Paczesny; Susan Burkeholder; Knut M Wittkowski; Ralph M Steinman; Joseph Fay; Jacques Banchereau
Single injection of CD34+ progenitor-derived dendritic cell vaccine can lead to induction of T-cell immunity in patients with stage IV melanoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2003;26(5):432-9.
2003: Te Piao King; Sui Yee Jim; Knut M Wittkowski
Inflammatory role of two venom components of yellow jackets (Vespula vulgaris): a mast cell degranulating peptide mastoparan and phospholipase A1.
International archives of allergy and immunology 2003;131(1):25-32.
2003: Jonathan D. Smith; Daylon James; Hayes M Dansky; Knut M Wittkowski; Karen J Moore; Jan L Breslow
In silico quantitative trait locus map for atherosclerosis susceptibility in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(1):117-22.
2002: Eric Scott Sills; Knut M Wittkowski; Michael J Tucker; Mark Perloe; Carolyn R Kaplan; Gianpiero D Palermo
Comparison of centrifugation- and noncentrifugation-based techniques for recovery of motile human sperm in assisted reproduction.
Archives of andrology 2002;48(2):141-5.
2002: Knut M Wittkowski; Xin Liu
A statistically valid alternative to the TDT.
Human heredity 2002;54(3):157-64.
2001: B Rigas; I Hasan; R Rehman; P Donahue; Knut M Wittkowski; E Lebovics
Effect on treatment outcome of coinfection with SEN viruses in patients with hepatitis C.
Lancet 2001;358(9297):1961-2.
2001: Jacques Banchereau; A Karolina Palucka; Madhav V Dhodapkar; Susan Burkeholder; N Taquet; A Rolland; S Taquet; S Coquery; Knut M Wittkowski; N Bhardwaj; LA Pineiro; R Steinman; Joseph Fay
Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine.
Cancer research 2001;61(17):6451-8.
2000: Knut M Wittkowski
Further thoughts about vaginal microbicide testing.
American journal of public health 2000;90(7):1155-6.
2000: Knut M Wittkowski
A new approach to adjust for multivariate confounders in small randomized studies applied to dendritic cell vaccination data.
Studies in health technology and informatics 2000;77():321-4.
1999: Knut M Wittkowski; S J Shiff; J Hirsch
Dietary fat and risk of breast cancer.
JAMA : the journal of the American Medical Association 1999;282(13):1223-4; author reply 1224.
1998: Ezra Susser; Moïse Desvarieux; Knut M Wittkowski
Reporting sexual risk behavior for HIV: a practical risk index and a method for improving risk indices.
American journal of public health 1998;88(4):671-4.
1998: Knut M Wittkowski; Ezra Susser; K Dietz
The protective effect of condoms and nonoxynol-9 against HIV infection.
American journal of public health 1998;88(4):590-6.
1998: Stefan Sell; Christoph Gaissmaier; Jürgen Fritz; G Herr; Stefan A Esenwein; W Küsswetter; Rüdiger Volkmann; Knut M Wittkowski; H Peter Rodemann
Different behavior of human osteoblast-like cells isolated from normal and heterotopic bone In vitro.
Calcified tissue international 1998;62(1):51-9.
1997: Knut M Wittkowski
The efficacy of nonoxynol-9 from an in vivo point of view.
AIDS (London, England) 1997;11(3):392-4.
1996: Knut M Wittkowski
[Epidemiology of HIV in Germany (status: 30 June 1995)--transmission among heterosexuals and value of HIV screening programs].
Gesundheitswesen (Bundesverband der Ärzte des Öffentlichen Gesundheitsdienstes (Germany)) 1996;58(4):229-33.
1995: Hermann Einsele; Gerhard Ehninger; Holger Hebart; Knut M Wittkowski; Ulrich Schuler; Gerhard Jahn; P Mackes; M Herter; Thomas Klingebiel; Jürgen Löffler; S Wagner; CA Müller
Polymerase chain reaction monitoring reduces the incidence of cytomegalovirus disease and the duration and side effects of antiviral therapy after bone marrow transplantation.
Blood 1995;86(7):2815-20.
1995: Knut M Wittkowski
[Epidemiology of HIV in Germany].
Gesundheitswesen (Bundesverband der Ärzte des Öffentlichen Gesundheitsdienstes (Germany)) 1995;57(5):291-8.
1995: Knut M Wittkowski
The potential of nonoxynol-9 for the prevention of HIV infection reconsidered.
AIDS (London, England) 1995;9(3):310-1.
1994: J Seydel; A Krämer; P S Rosenberg; Knut M Wittkowski; M H Gail
Backcalculation of the number infected with human immunodeficiency virus in Germany.
Journal of acquired immune deficiency syndromes 1994;7(1):74-8.
1991: Knut M Wittkowski
A structured visual language for a knowledge-based front-end to statistical analysis systems in biomedical research.
Computer methods and programs in biomedicine 1991;35(1):59-67.
1990: Knut M Wittkowski
Statistical knowledge-based systems--critical remarks and requirements for approval.
Computer methods and programs in biomedicine 1990;33(4):255-9.
1990: T Rammsayer; Knut M Wittkowski
[Time order error and position effect of a standardized stimulus in discrimination of short time duration].
Archiv für Psychologie 1990;142(2):81-9.
1989: J ter Meulen; Knut M Wittkowski; J J Kidenya; M Pöllath; Rüdiger Dörries; K Fleischer; K Dietz; Volker ter Meulen
Evaluation of seroepidemiological associations between HIV-infection, hepatitis B and other sexually transmitted diseases in African patients.
European journal of epidemiology 1989;5(2):158-63.
1989: Knut M Wittkowski
Preventing the heterosexual spread of AIDS: what is the best advice if compliance is taken into account?
AIDS (London, England) 1989;3(3):143-5.
1989: Knut M Wittkowski
[Prevention of HIV infection. I. Assessing the effectiveness of barrier methods for HIV prevention].
AIDS-Forschung : AIFO = Acquired immune deficiency syndrome research 1989;4(1):3-8.
1988: Heinz Guggenberger; T Fritz; E Guggenberger; H Warth; Knut M Wittkowski; D Heuser
[Complaints in the postoperative phase related to anesthetics].
Der Anaesthesist 1988;37(12):746-51.