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rob cross

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Miho Katsuki; Douglas R Drummond; Michael Osei; rob cross
Mal3 masks catastrophe events in Schizosaccharomyces pombe microtubules by inhibiting shrinkage and promoting rescue.
Kuniyoshi Kaseda; Andrew D McAinsh; rob cross
Walking, hopping, diffusing and braking modes of kinesin-5.
Marcus Braun; Douglas R Drummond; rob cross; Andrew D McAinsh
The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism.

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All Publications

2009: Miho Katsuki; Douglas R Drummond; Michael Osei; rob cross
Mal3 masks catastrophe events in Schizosaccharomyces pombe microtubules by inhibiting shrinkage and promoting rescue.
The Journal of biological chemistry 2009;284(43):29246-50.
2009: Kuniyoshi Kaseda; Andrew D McAinsh; rob cross
Walking, hopping, diffusing and braking modes of kinesin-5.
Biochemical Society transactions 2009;37(Pt 5):1045-9.
2009: Marcus Braun; Douglas R Drummond; rob cross; Andrew D McAinsh
The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism.
Nature cell biology 2009;11(6):724-30.
2008: Amédée des Georges; Miho Katsuki; Douglas R Drummond; Michael Osei; rob cross; Linda A Amos
Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice.
Nature structural & molecular biology 2008;15(10):1102-8.
2008: Kuniyoshi Kaseda; Isabelle Crevel; Keiko Hirose; rob cross
Single-headed mode of kinesin-5.
EMBO reports 2008;9(8):761-5.
2008: Sarah Dunn; Ewan E Morrison; Tanniemola B Liverpool; Carmen Molina-París; rob cross; Maria C Alonso; Michelle Peckham
Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells.
Journal of cell science 2008;121(Pt 7):1085-95.
2007: Barry Grant; J Andrew McCammon; Leo S D Caves; rob cross
Multivariate analysis of conserved sequence-structure relationships in kinesins: coupling of the active site and a tubulin-binding sub-domain.
Journal of molecular biology 2007;368(5):1231-48.
2007: Maria C Alonso; Douglas R Drummond; Susan Kain; Julia Hoeng; Linda Amos; rob cross
An ATP gate controls tubulin binding by the tethered head of kinesin-1.
Science (New York, N.Y.) 2007;316(5821):120-3.
2006: Carolyn A Moores; Mylène Perderiset; Caroline Kappeler; Susan Kain; Douglas Drummond; Stephen J Perkins; Jamel Chelly; rob cross; Anne Houdusse; Fiona Francis
Distinct roles of doublecortin modulating the microtubule cytoskeleton.
The EMBO journal 2006;25(19):4448-57.
2006: Dimitrios A Skoufias; Salvatore DeBonis; Yasmina Saoudi; Luc Lebeau; Isabelle Crevel; rob cross; Richard H Wade; David Hackney; Frank Kozielski
S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression.
The Journal of biological chemistry 2006;281(26):17559-69.
2006: rob cross
Myosin's mechanical ratchet.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):8911-2.
2006: Nicholas J Carter; rob cross
Kinesin's moonwalk.
Current opinion in cell biology 2006;18(1):61-7.
2005: Junichiro Yajima; rob cross
A torque component in the kinesin-1 power stroke.
Nature chemical biology 2005;1(6):338-41.
2005: Nicholas J Carter; rob cross
Mechanics of the kinesin step.
Nature 2005;435(7040):308-12.
2004: Verena Eickel; Douglas Drummond; Nick Carter; ANDREW LOCKHART; John Kendrick Jones; rob cross
Kinesin heads fused to hinge-free myosin tails drive efficient motility.
FEBS letters 2004;569(1-3):54-8.
2004: Isabelle Crevel; Maria C Alonso; rob cross
Monastrol stabilises an attached low-friction mode of Eg5.
Current biology : CB 2004;14(11):R411-2.
2004: rob cross
The kinetic mechanism of kinesin.
Trends in biochemical sciences 2004;29(6):301-9.
2004: rob cross
Molecular motors: Dynein's gearbox.
Current biology : CB 2004;14(9):R355-6.
2004: rob cross
Molecular motors: kinesin's interesting limp.
Current biology : CB 2004;14(4):R158-9.
2004: Isabelle Crevel; Miklós Nyitrai; Maria C Alonso; Stefan Weiss; Michael A Geeves; rob cross
What kinesin does at roadblocks: the coordination mechanism for molecular walking.
The EMBO journal 2004;23(1):23-32.
2003: Salvatore DeBonis; Jean-Pierre Simorre; Isabelle Crevel; Luc Lebeau; Dimitrios A Skoufias; Anne Blangy; Christine Ebel; Pierre Gans; rob cross; David D Hackney; Richard H Wade; Frank Kozielski
Interaction of the mitotic inhibitor monastrol with human kinesin Eg5.
Biochemistry 2003;42(2):338-49.
2002: Douglas R Drummond; N Carter; rob cross
Multiphoton versus confocal high resolution z-sectioning of enhanced green fluorescent microtubules: increased multiphoton photobleaching within the focal plane can be compensated using a Pockels cell and dual widefield detectors.
Journal of microscopy 2002;206(Pt 2):161-9.
2002: Junichiro Yajima; Maria C Alonso; rob cross; Yoko Y Toyoshima
Direct long-term observation of kinesin processivity at low load.
Current biology : CB 2002;12(4):301-6.
2002: Olga Krylyshkina; Irina Kaverina; Wolfgang Kranewitter; Walter Steffen; Maria C Alonso; rob cross; J Victor Small
Modulation of substrate adhesion dynamics via microtubule targeting requires kinesin-1.
The Journal of cell biology 2002;156(2):349-59.
2001: Athina Kallipolitou; Dominga Deluca; U Majdic; Stefan Lakämper; rob cross; Edgar Meyhöfer; Luis Moroder; Manfred Schliwa; Günther Woehlke
Unusual properties of the fungal conventional kinesin neck domain from Neurospora crassa.
The EMBO journal 2001;20(22):6226-35.
2001: K R Rogers; S Weiss; Isabelle Crevel; Peter J Brophy; Michael A Geeves; rob cross
KIF1D is a fast non-processive kinesin that demonstrates novel K-loop-dependent mechanochemistry.
The EMBO journal 2001;20(18):5101-13.
2001: rob cross
Molecular motors: Kinesin's string variable.
Current biology : CB 2001;11(4):R147-9.
2001: Nick Carter; rob cross
An improved microscope for bead and surface-based motility assays.
Methods in molecular biology (Clifton, N.J.) 2001;164():73-89.
2000: K Hirose; U Henningsen; Manfred Schliwa; Chikashi Toyoshima; T Shimizu; M Alonso; rob cross; Linda Amos
Structural comparison of dimeric Eg5, Neurospora kinesin (Nkin) and Ncd head-Nkin neck chimera with conventional kinesin.
The EMBO journal 2000;19(20):5308-14.
2000: rob cross
Motor proteins. Directing direction.
Nature 2000;406(6798):839-40.
2000: Douglas R Drummond; rob cross
Dynamics of interphase microtubules in Schizosaccharomyces pombe.
Current biology : CB 2000;10(13):766-75.
2000: rob cross; Isabelle Crevel; Nicholas J Carter; Maria C Alonso; K Hirose; Linda Amos
The conformational cycle of kinesin.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2000;355(1396):459-64.
2000: rob cross; Nicholas J Carter
Molecular motors.
Current biology : CB 2000;10(5):R177-9.
2000: K I Anderson; rob cross
Contact dynamics during keratocyte motility.
Current biology : CB 2000;10(5):253-60.
2000: Dan Veniamin Nicolau; rob cross
Protein profiled features patterned via confocal microscopy.
Biosensors & bioelectronics 2000;15(1-2):85-91.
2000: rob cross
Molecular motors: Kinesin's dynamically dockable neck.
Current biology : CB 2000;10(3):R124-6.
2000: rob cross
Introduction: the mechano-biochemistry of molecular motors.
Essays in biochemistry 2000;35():1-2.
1999: rob cross
Molecular motors: Walking talking heads.
Current biology : CB 1999;9(22):R854-6.
1999: Isabelle Crevel; Nick Carter; Manfred Schliwa; rob cross
Coupled chemical and mechanical reaction steps in a processive Neurospora kinesin.
The EMBO journal 1999;18(21):5863-72.
1999: K Hirose; Jan Löwe; M Alonso; rob cross; Linda Amos
3D electron microscopy of the interaction of kinesin with tubulin.
Cell structure and function 1999;24(5):277-84.
1999: rob cross; J Scholey
Kinesin: the tail unfolds.
Nature cell biology 1999;1(5):E119-21.
1999: K Hirose; Jan Löwe; M Alonso; rob cross; Linda Amos
Congruent docking of dimeric kinesin and ncd into three-dimensional electron cryomicroscopy maps of microtubule-motor ADP complexes.
Molecular biology of the cell 1999;10(6):2063-74.
1998: M Mazumdar; rob cross
Engineering a lever into the kinesin neck.
The Journal of biological chemistry 1998;273(45):29352-9.
1998: K Hirose; rob cross; Linda Amos
Nucleotide-dependent structural changes in dimeric NCD molecules complexed to microtubules.
Journal of molecular biology 1998;278(2):389-400.
1998: Maria C Alonso; J van Damme; J Vandekerckhove; rob cross
Proteolytic mapping of kinesin/ncd-microtubule interface: nucleotide-dependent conformational changes in the loops L8 and L12.
The EMBO journal 1998;17(4):945-51.
1997: Isabelle Crevel; ANDREW LOCKHART; rob cross
Kinetic evidence for low chemical processivity in ncd and Eg5.
Journal of molecular biology 1997;273(1):160-70.
1997: rob cross
Molecular motors: the natural economy of kinesin.
Current biology : CB 1997;7(10):R631-3.
1997: rob cross
Reversing the kinesin ratchet--a diverting tail.
Nature 1997;389(6646):15-6.
1997: Linda Amos; rob cross
Structure and dynamics of molecular motors.
Current opinion in structural biology 1997;7(2):239-46.
1997: K Hirose; W B Amos; ANDREW LOCKHART; rob cross; Linda Amos
Three-dimensional cryoelectron microscopy of 16-protofilament microtubules: structure, polarity, and interaction with motor proteins.
Journal of structural biology 1997;118(2):140-8.
1997: rob cross
A protein-making motor protein.
Nature 1997;385(6611):18-9.
1996: K Hirose; ANDREW LOCKHART; rob cross; Linda Amos
Three-dimensional cryoelectron microscopy of dimeric kinesin and ncd motor domains on microtubules.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9539-44.
1996: J Fan; A D Griffiths; ANDREW LOCKHART; rob cross; Linda Amos
Microtubule minus ends can be labelled with a phage display antibody specific to alpha-tubulin.
Journal of molecular biology 1996;259(3):325-30.
1996: I M Crevel; ANDREW LOCKHART; rob cross
Weak and strong states of kinesin and ncd.
Journal of molecular biology 1996;257(1):66-76.
1996: ANDREW LOCKHART; rob cross
Kinetics and motility of the Eg5 microtubule motor.
Biochemistry 1996;35(7):2365-73.
1995: ANDREW LOCKHART; rob cross; D F McKillop
ADP release is the rate-limiting step of the MT activated ATPase of non-claret disjunctional and kinesin.
FEBS letters 1995;368(3):531-5.
1995: K Hirose; ANDREW LOCKHART; rob cross; Linda Amos
Nucleotide-dependent angular change in kinesin motor domain bound to tubulin.
Nature 1995;376(6537):277-9.
1995: ANDREW LOCKHART; I M Crevel; rob cross
Kinesin and ncd bind through a single head to microtubules and compete for a shared MT binding site.
Journal of molecular biology 1995;249(4):763-71.
1995: rob cross
On the hand-over-hand footsteps of kinesin heads.
Journal of muscle research and cell motility 1995;16(2):91-4.
1994: A J North; Mario Gimona; rob cross; J Victor Small
Calponin is localised in both the contractile apparatus and the cytoskeleton of smooth muscle cells.
Journal of cell science 1994;107 ( Pt 3)():437-44.
1994: ANDREW LOCKHART; rob cross
Origins of reversed directionality in the ncd molecular motor.
The EMBO journal 1994;13(4):751-7.
1993: A R Faruqi; rob cross; John Kendrick-Jones
Structural studies on the conformations of myosin.
Advances in experimental medicine and biology 1993;332():81-9; discussion 89-91.
1992: rob cross; J K Jones
MgATP binding changes neither the shape nor the flexibility of the heads of single myosin molecules.
Journal of structural biology 1992;109(3):208-13.
1992: M Way; Brian J Pope; rob cross; John Kendrick-Jones; Alan G Weeds
Expression of the N-terminal domain of dystrophin in E. coli and demonstration of binding to F-actin.
FEBS letters 1992;301(3):243-5.
1991: rob cross; A Engel
Scanning transmission electron microscopic mass determination of in vitro self-assembled smooth muscle myosin filaments.
Journal of molecular biology 1991;222(3):455-8.
1991: rob cross; M A Geeves; John Kendrick-Jones
A nucleation--elongation mechanism for the self-assembly of side polar sheets of smooth muscle myosin.
The EMBO journal 1991;10(4):747-56.
1991: R J Ankrett; Arthur J Rowe; rob cross; John Kendrick-Jones; Clive R Bagshaw
A folded (10 S) conformer of myosin from a striated muscle and its implications for regulation of ATPase activity.
Journal of molecular biology 1991;217(2):323-35.
1991: A R Faruqi; rob cross; John Kendrick-Jones
Small angle X-ray scattering studies on myosin.
Journal of cell science. Supplement 1991;14():23-6.
1991: rob cross; T P Hodge; John Kendrick-Jones
Self-assembly pathway of nonsarcomeric myosin II.
Journal of cell science. Supplement 1991;14():17-21.
1990: Charles Redwood; Steven B Marston; J Bryan; rob cross; J Kendrick-Jones
The functional properties of full length and mutant chicken gizzard smooth muscle caldesmon expressed in Escherichia coli.
FEBS letters 1990;270(1-2):53-6.
1990: rob cross; Murray Stewart; John Kendrick-Jones
Structural predictions for the central domain of dystrophin.
FEBS letters 1990;262(1):87-92.
1989: S Citi; rob cross; Clive R Bagshaw; John Kendrick-Jones
Parallel modulation of brush border myosin conformation and enzyme activity induced by monoclonal antibodies.
The Journal of cell biology 1989;109(2):549-56.
1989: rob cross
Smooth operators. The molecular mechanics of smooth muscle contraction.
BioEssays : news and reviews in molecular, cellular and developmental biology 1989;11(1):18-21.
1988: J P Bennett; rob cross; John Kendrick-Jones; Alan G Weeds
Spatial pattern of myosin phosphorylation in contracting smooth muscle cells: evidence for contractile zones.
The Journal of cell biology 1988;107(6 Pt 2):2623-9.
1988: rob cross; A P Jackson; S Citi; John Kendrick-Jones; Clive R Bagshaw
Active site trapping of nucleotide by smooth and non-muscle myosins.
Journal of molecular biology 1988;203(1):173-81.
1988: rob cross; S Citi; John Kendrick-Jones
How phosphorylation controls the self-assembly of vertebrate smooth and non-muscle myosins.
Biochemical Society transactions 1988;16(4):501-3.
1988: rob cross
What is 10S myosin for?
Journal of muscle research and cell motility 1988;9(1):108-10.
1987: rob cross; K E Cross; J Victor Small
Salt dependent dimerisation of caldesmon.
FEBS letters 1987;219(2):306-10.
1986: rob cross; K E Cross; Apolinary Sobieszek
ATP-linked monomer-polymer equilibrium of smooth muscle myosin: the free folded monomer traps ADP.Pi.
The EMBO journal 1986;5(10):2637-41.
1986: rob cross; J Vandekerckhove
Solubility-determining domain of smooth muscle myosin rod.
FEBS letters 1986;200(2):355-60.
1986: D O Fürst; rob cross; J De Mey; J Victor Small
Caldesmon is an elongated, flexible molecule localized in the actomyosin domains of smooth muscle.
The EMBO journal 1986;5(2):251-7.
1985: rob cross; Apolinary Sobieszek
Influence of smooth muscle myosin conformation on myosin light chain kinase binding and on phosphorylation.
FEBS letters 1985;188(2):367-74.
1984: rob cross; R G Bardsley; D A Ledward; J Victor Small; Apolinary Sobieszek
Conformational stability of the myosin rod.
European journal of biochemistry / FEBS 1984;145(2):305-10.
1984: rob cross
Bending of smooth muscle myosin rod.
FEBS letters 1984;176(1):197-201.